Details of the Target

General Information of Target

Target ID LDTP05062
Target Name SUMO-conjugating enzyme UBC9 (UBE2I)
Gene Name UBE2I
Gene ID 7329
Synonyms
UBC9; UBCE9; SUMO-conjugating enzyme UBC9; EC 2.3.2.-; RING-type E3 SUMO transferase UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; p18
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKL
RMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELL
NEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
Target Bioclass
Enzyme
Family
Ubiquitin-conjugating enzyme family
Subcellular location
Nucleus
Function
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.
Uniprot ID
P63279
Ensemble ID
ENST00000325437.9
HGNC ID
HGNC:12485
ChEMBL ID
CHEMBL1741191

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 26 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		14.05  LDD0402  [1]
TH214
 Probe Info  		Y68(6.92)  LDD0258  [2]
TH216
 Probe Info  		Y68(9.01)  LDD0259  [2]
BTD
 Probe Info  		C75(2.45)  LDD1699  [3]
ONAyne
 Probe Info  		K18(0.00); K146(0.00)  LDD0273  [4]
Probe 1
 Probe Info  		Y68(46.60)  LDD3495  [5]
AHL-Pu-1
 Probe Info  		C138(2.23)  LDD0170  [6]
HHS-482
 Probe Info  		Y68(0.40)  LDD0286  [7]
Acrolein
 Probe Info  		H20(0.00); C43(0.00)  LDD0221  [8]
DBIA
 Probe Info  		C43(0.97)  LDD0593  [9]
5E-2FA
 Probe Info  		N.A.  LDD2235  [10]
ATP probe
 Probe Info  		K74(0.00); K76(0.00); K49(0.00)  LDD0199  [11]
4-Iodoacetamidophenylacetylene
 Probe Info  		C43(0.00); C93(0.00); C138(0.00)  LDD0038  [12]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [13]
IPIAA_H
 Probe Info  		C43(0.00); C93(0.00)  LDD0030  [14]
IPIAA_L
 Probe Info  		C93(0.00); C75(0.00); C43(0.00); C138(0.00)  LDD0031  [14]
Lodoacetamide azide
 Probe Info  		C43(0.00); C93(0.00); C138(0.00)  LDD0037  [12]
ATP probe
 Probe Info  		N.A.  LDD0035  [15]
IPM
 Probe Info  		C43(0.00); C138(0.00)  LDD2156  [16]
NHS
 Probe Info  		K18(0.00); K49(0.00)  LDD0010  [17]
SF
 Probe Info  		N.A.  LDD0028  [18]
STPyne
 Probe Info  		K76(0.00); K74(0.00); K18(0.00)  LDD0009  [17]
1c-yne
 Probe Info  		N.A.  LDD0228  [19]
W1
 Probe Info  		C43(0.00); C93(0.00)  LDD0236  [20]
AOyne
 Probe Info  		15.00  LDD0443  [21]
NAIA_5
 Probe Info  		C75(0.00); C43(0.00)  LDD2223  [22]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe13
 Probe Info  		11.21  LDD0475  [23]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C75(0.38)  LDD2142  [3]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C75(0.58)  LDD2112  [3]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C75(0.58)  LDD2095  [3]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C75(0.79)  LDD2117  [3]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C75(1.17)  LDD2152  [3]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C75(0.63)  LDD2131  [3]
 LDCM0025  4SU-RNA DM93 C138(2.23)  LDD0170  [6]
 LDCM0214  AC1 PaTu 8988t C138(1.66)  LDD1093  [9]
 LDCM0215  AC10 HEK-293T C138(0.73)  LDD0813  [9]
 LDCM0216  AC100 HEK-293T C138(0.73)  LDD0814  [9]
 LDCM0217  AC101 HEK-293T C138(0.79)  LDD0815  [9]
 LDCM0218  AC102 HEK-293T C138(0.75)  LDD0816  [9]
 LDCM0219  AC103 HEK-293T C138(0.69)  LDD0817  [9]
 LDCM0220  AC104 HEK-293T C138(0.79)  LDD0818  [9]
 LDCM0221  AC105 HEK-293T C138(1.13)  LDD0819  [9]
 LDCM0222  AC106 HEK-293T C138(1.22)  LDD0820  [9]
 LDCM0223  AC107 HEK-293T C138(0.81)  LDD0821  [9]
 LDCM0224  AC108 HEK-293T C138(1.08)  LDD0822  [9]
 LDCM0225  AC109 HEK-293T C138(1.03)  LDD0823  [9]
 LDCM0226  AC11 HEK-293T C138(0.83)  LDD0824  [9]
 LDCM0227  AC110 HEK-293T C138(0.71)  LDD0825  [9]
 LDCM0228  AC111 HEK-293T C138(0.83)  LDD0826  [9]
 LDCM0229  AC112 HEK-293T C138(0.70)  LDD0827  [9]
 LDCM0230  AC113 HEK-293T C138(1.06)  LDD0828  [9]
 LDCM0231  AC114 HEK-293T C138(0.88)  LDD0829  [9]
 LDCM0232  AC115 HEK-293T C138(0.80)  LDD0830  [9]
 LDCM0233  AC116 HEK-293T C138(0.79)  LDD0831  [9]
 LDCM0234  AC117 HEK-293T C138(0.60)  LDD0832  [9]
 LDCM0235  AC118 HEK-293T C138(0.53)  LDD0833  [9]
 LDCM0236  AC119 HEK-293T C138(0.43)  LDD0834  [9]
 LDCM0237  AC12 HEK-293T C138(0.67)  LDD0835  [9]
 LDCM0238  AC120 HEK-293T C138(0.64)  LDD0836  [9]
 LDCM0239  AC121 HEK-293T C138(0.57)  LDD0837  [9]
 LDCM0240  AC122 HEK-293T C138(0.50)  LDD0838  [9]
 LDCM0241  AC123 HEK-293T C138(0.47)  LDD0839  [9]
 LDCM0242  AC124 HEK-293T C138(0.55)  LDD0840  [9]
 LDCM0243  AC125 HEK-293T C138(0.43)  LDD0841  [9]
 LDCM0244  AC126 HEK-293T C138(0.60)  LDD0842  [9]
 LDCM0245  AC127 HEK-293T C138(0.54)  LDD0843  [9]
 LDCM0246  AC128 HEK-293T C138(0.87)  LDD0844  [9]
 LDCM0247  AC129 HEK-293T C138(0.62)  LDD0845  [9]
 LDCM0249  AC130 HEK-293T C138(0.74)  LDD0847  [9]
 LDCM0250  AC131 HEK-293T C138(1.02)  LDD0848  [9]
 LDCM0251  AC132 HEK-293T C138(0.85)  LDD0849  [9]
 LDCM0252  AC133 HEK-293T C138(0.59)  LDD0850  [9]
 LDCM0253  AC134 HEK-293T C138(0.50)  LDD0851  [9]
 LDCM0254  AC135 HEK-293T C138(0.59)  LDD0852  [9]
 LDCM0255  AC136 HEK-293T C138(0.66)  LDD0853  [9]
 LDCM0256  AC137 HEK-293T C138(0.61)  LDD0854  [9]
 LDCM0257  AC138 HEK-293T C138(0.75)  LDD0855  [9]
 LDCM0258  AC139 HEK-293T C138(0.55)  LDD0856  [9]
 LDCM0259  AC14 HEK-293T C138(0.60)  LDD0857  [9]
 LDCM0260  AC140 HEK-293T C138(0.53)  LDD0858  [9]
 LDCM0261  AC141 HEK-293T C138(0.60)  LDD0859  [9]
 LDCM0262  AC142 HEK-293T C138(0.61)  LDD0860  [9]
 LDCM0263  AC143 HEK-293T C138(0.71)  LDD0861  [9]
 LDCM0264  AC144 HEK-293T C138(0.68)  LDD0862  [9]
 LDCM0265  AC145 HEK-293T C138(0.61)  LDD0863  [9]
 LDCM0266  AC146 HEK-293T C138(0.54)  LDD0864  [9]
 LDCM0267  AC147 HEK-293T C138(0.56)  LDD0865  [9]
 LDCM0268  AC148 HEK-293T C138(0.58)  LDD0866  [9]
 LDCM0269  AC149 HEK-293T C138(0.73)  LDD0867  [9]
 LDCM0270  AC15 HEK-293T C138(0.44)  LDD0868  [9]
 LDCM0271  AC150 HEK-293T C138(0.58)  LDD0869  [9]
 LDCM0272  AC151 HEK-293T C138(0.59)  LDD0870  [9]
 LDCM0273  AC152 HEK-293T C138(0.61)  LDD0871  [9]
 LDCM0274  AC153 HEK-293T C138(0.57)  LDD0872  [9]
 LDCM0621  AC154 HEK-293T C138(0.70)  LDD2162  [9]
 LDCM0622  AC155 HEK-293T C138(0.69)  LDD2163  [9]
 LDCM0623  AC156 HEK-293T C138(0.55)  LDD2164  [9]
 LDCM0624  AC157 HEK-293T C138(0.59)  LDD2165  [9]
 LDCM0276  AC17 HCT 116 C43(0.97)  LDD0593  [9]
 LDCM0277  AC18 HCT 116 C43(0.65)  LDD0594  [9]
 LDCM0278  AC19 HCT 116 C43(0.86)  LDD0595  [9]
 LDCM0279  AC2 PaTu 8988t C138(1.30)  LDD1158  [9]
 LDCM0280  AC20 HCT 116 C43(0.90)  LDD0597  [9]
 LDCM0281  AC21 HCT 116 C43(0.80)  LDD0598  [9]
 LDCM0282  AC22 HCT 116 C43(0.95)  LDD0599  [9]
 LDCM0283  AC23 HCT 116 C43(0.74)  LDD0600  [9]
 LDCM0284  AC24 HCT 116 C43(1.06)  LDD0601  [9]
 LDCM0285  AC25 PaTu 8988t C138(0.92)  LDD1164  [9]
 LDCM0286  AC26 PaTu 8988t C138(1.01)  LDD1165  [9]
 LDCM0287  AC27 PaTu 8988t C138(1.39)  LDD1166  [9]
 LDCM0288  AC28 PaTu 8988t C138(1.43)  LDD1167  [9]
 LDCM0289  AC29 PaTu 8988t C138(1.01)  LDD1168  [9]
 LDCM0290  AC3 PaTu 8988t C138(1.42)  LDD1169  [9]
 LDCM0291  AC30 PaTu 8988t C138(1.33)  LDD1170  [9]
 LDCM0292  AC31 PaTu 8988t C138(1.23)  LDD1171  [9]
 LDCM0293  AC32 PaTu 8988t C138(1.38)  LDD1172  [9]
 LDCM0294  AC33 PaTu 8988t C138(1.17)  LDD1173  [9]
 LDCM0295  AC34 PaTu 8988t C138(1.29)  LDD1174  [9]
 LDCM0296  AC35 HEK-293T C138(0.75)  LDD0894  [9]
 LDCM0297  AC36 HEK-293T C138(0.73)  LDD0895  [9]
 LDCM0298  AC37 HEK-293T C138(0.66)  LDD0896  [9]
 LDCM0299  AC38 HEK-293T C138(0.72)  LDD0897  [9]
 LDCM0300  AC39 HEK-293T C138(0.74)  LDD0898  [9]
 LDCM0301  AC4 PaTu 8988t C138(1.32)  LDD1180  [9]
 LDCM0302  AC40 HEK-293T C138(0.99)  LDD0900  [9]
 LDCM0303  AC41 HEK-293T C138(0.82)  LDD0901  [9]
 LDCM0304  AC42 HEK-293T C138(0.72)  LDD0902  [9]
 LDCM0305  AC43 HEK-293T C138(0.69)  LDD0903  [9]
 LDCM0306  AC44 HEK-293T C138(0.66)  LDD0904  [9]
 LDCM0307  AC45 HEK-293T C138(0.69)  LDD0905  [9]
 LDCM0308  AC46 HCT 116 C43(0.98)  LDD0625  [9]
 LDCM0309  AC47 HCT 116 C43(0.78)  LDD0626  [9]
 LDCM0310  AC48 HCT 116 C43(0.93)  LDD0627  [9]
 LDCM0311  AC49 HCT 116 C43(0.29)  LDD0628  [9]
 LDCM0312  AC5 PaTu 8988t C138(2.06)  LDD1191  [9]
 LDCM0313  AC50 HCT 116 C43(0.36)  LDD0630  [9]
 LDCM0314  AC51 HCT 116 C43(1.37)  LDD0631  [9]
 LDCM0315  AC52 HCT 116 C43(0.90)  LDD0632  [9]
 LDCM0316  AC53 HCT 116 C43(0.58)  LDD0633  [9]
 LDCM0317  AC54 HCT 116 C43(0.56)  LDD0634  [9]
 LDCM0318  AC55 HCT 116 C43(0.32)  LDD0635  [9]
 LDCM0319  AC56 HCT 116 C43(0.08)  LDD0636  [9]
 LDCM0320  AC57 HEK-293T C43(0.78); C93(0.81); C138(0.92); C75(1.12)  LDD1559  [24]
 LDCM0321  AC58 HEK-293T C43(0.97); C93(0.98); C138(1.15)  LDD1560  [24]
 LDCM0322  AC59 HEK-293T C43(0.90); C93(1.10); C138(0.98); C75(1.07)  LDD1561  [24]
 LDCM0323  AC6 HEK-293T C138(1.03)  LDD0921  [9]
 LDCM0324  AC60 HEK-293T C43(0.83); C93(0.90); C138(1.15); C75(0.98)  LDD1563  [24]
 LDCM0325  AC61 HEK-293T C43(1.00); C93(1.08); C138(1.08); C75(1.27)  LDD1564  [24]
 LDCM0326  AC62 HEK-293T C43(0.92); C93(0.94); C138(1.20); C75(1.38)  LDD1565  [24]
 LDCM0327  AC63 HEK-293T C93(1.03); C138(0.91); C75(0.94)  LDD1566  [24]
 LDCM0328  AC64 HEK-293T C93(0.99); C138(1.00); C75(1.12); C75(1.11)  LDD1567  [24]
 LDCM0332  AC68 HEK-293T C138(0.82)  LDD0930  [9]
 LDCM0333  AC69 HEK-293T C138(0.71)  LDD0931  [9]
 LDCM0334  AC7 HEK-293T C138(0.72)  LDD0932  [9]
 LDCM0335  AC70 HEK-293T C138(0.69)  LDD0933  [9]
 LDCM0336  AC71 HEK-293T C138(0.72)  LDD0934  [9]
 LDCM0337  AC72 HEK-293T C138(0.71)  LDD0935  [9]
 LDCM0338  AC73 HEK-293T C138(0.78)  LDD0936  [9]
 LDCM0339  AC74 HEK-293T C138(0.59)  LDD0937  [9]
 LDCM0340  AC75 HEK-293T C138(0.61)  LDD0938  [9]
 LDCM0341  AC76 HEK-293T C138(0.71)  LDD0939  [9]
 LDCM0342  AC77 HEK-293T C138(0.59)  LDD0940  [9]
 LDCM0343  AC78 HEK-293T C138(0.52)  LDD0941  [9]
 LDCM0344  AC79 HEK-293T C138(0.78)  LDD0942  [9]
 LDCM0345  AC8 HEK-293T C138(0.58)  LDD0943  [9]
 LDCM0346  AC80 HEK-293T C138(0.50)  LDD0944  [9]
 LDCM0347  AC81 HEK-293T C138(0.58)  LDD0945  [9]
 LDCM0348  AC82 HEK-293T C138(0.38)  LDD0946  [9]
 LDCM0349  AC83 HEK-293T C138(1.05)  LDD0947  [9]
 LDCM0350  AC84 HEK-293T C138(0.58)  LDD0948  [9]
 LDCM0351  AC85 HEK-293T C138(0.65)  LDD0949  [9]
 LDCM0352  AC86 HEK-293T C138(0.61)  LDD0950  [9]
 LDCM0353  AC87 HEK-293T C138(0.58)  LDD0951  [9]
 LDCM0354  AC88 HEK-293T C138(0.45)  LDD0952  [9]
 LDCM0355  AC89 HEK-293T C138(0.40)  LDD0953  [9]
 LDCM0357  AC90 HEK-293T C138(0.48)  LDD0955  [9]
 LDCM0358  AC91 HEK-293T C138(0.51)  LDD0956  [9]
 LDCM0359  AC92 HEK-293T C138(0.56)  LDD0957  [9]
 LDCM0360  AC93 HEK-293T C138(0.54)  LDD0958  [9]
 LDCM0361  AC94 HEK-293T C138(0.39)  LDD0959  [9]
 LDCM0362  AC95 HEK-293T C138(0.46)  LDD0960  [9]
 LDCM0363  AC96 HEK-293T C138(0.46)  LDD0961  [9]
 LDCM0364  AC97 HEK-293T C138(0.42)  LDD0962  [9]
 LDCM0365  AC98 HEK-293T C138(1.14)  LDD0963  [9]
 LDCM0366  AC99 HEK-293T C138(1.05)  LDD0964  [9]
 LDCM0545  Acetamide MDA-MB-231 C75(0.28)  LDD2138  [3]
 LDCM0520  AKOS000195272 MDA-MB-231 C75(0.57)  LDD2113  [3]
 LDCM0248  AKOS034007472 HEK-293T C138(0.67)  LDD0846  [9]
 LDCM0356  AKOS034007680 HEK-293T C138(0.42)  LDD0954  [9]
 LDCM0275  AKOS034007705 HEK-293T C138(0.46)  LDD0873  [9]
 LDCM0156  Aniline NCI-H1299 12.71  LDD0403  [1]
 LDCM0108  Chloroacetamide HeLa C43(0.00); H20(0.00)  LDD0222  [8]
 LDCM0367  CL1 HCT 116 C43(0.94)  LDD0684  [9]
 LDCM0368  CL10 HCT 116 C43(0.41)  LDD0685  [9]
 LDCM0369  CL100 PaTu 8988t C138(1.20)  LDD1248  [9]
 LDCM0370  CL101 HEK-293T C138(0.50)  LDD0968  [9]
 LDCM0371  CL102 HEK-293T C138(0.47)  LDD0969  [9]
 LDCM0372  CL103 HEK-293T C138(0.44)  LDD0970  [9]
 LDCM0373  CL104 HEK-293T C138(0.54)  LDD0971  [9]
 LDCM0374  CL105 HCT 116 C43(0.70)  LDD0691  [9]
 LDCM0375  CL106 HCT 116 C43(0.35)  LDD0692  [9]
 LDCM0376  CL107 HCT 116 C43(0.53)  LDD0693  [9]
 LDCM0377  CL108 HCT 116 C43(0.43)  LDD0694  [9]
 LDCM0378  CL109 HCT 116 C43(0.69)  LDD0695  [9]
 LDCM0379  CL11 HCT 116 C43(0.38)  LDD0696  [9]
 LDCM0380  CL110 HCT 116 C43(0.57)  LDD0697  [9]
 LDCM0381  CL111 HCT 116 C43(0.74)  LDD0698  [9]
 LDCM0382  CL112 PaTu 8988t C138(1.13)  LDD1261  [9]
 LDCM0383  CL113 PaTu 8988t C138(1.13)  LDD1262  [9]
 LDCM0384  CL114 PaTu 8988t C138(1.15)  LDD1263  [9]
 LDCM0385  CL115 PaTu 8988t C138(1.13)  LDD1264  [9]
 LDCM0386  CL116 PaTu 8988t C138(1.27)  LDD1265  [9]
 LDCM0387  CL117 HEK-293T C138(0.69)  LDD0985  [9]
 LDCM0388  CL118 HEK-293T C138(0.67)  LDD0986  [9]
 LDCM0389  CL119 HEK-293T C138(0.57)  LDD0987  [9]
 LDCM0390  CL12 HCT 116 C43(0.35)  LDD0707  [9]
 LDCM0391  CL120 HEK-293T C138(0.90)  LDD0989  [9]
 LDCM0392  CL121 HCT 116 C43(0.60)  LDD0709  [9]
 LDCM0393  CL122 HCT 116 C43(0.61)  LDD0710  [9]
 LDCM0394  CL123 HCT 116 C43(0.54)  LDD0711  [9]
 LDCM0395  CL124 HCT 116 C43(0.45)  LDD0712  [9]
 LDCM0396  CL125 HEK-293T C43(0.71); C93(1.11); C138(1.19)  LDD1600  [24]
 LDCM0397  CL126 HEK-293T C43(0.90); C93(0.93); C138(1.07)  LDD1601  [24]
 LDCM0398  CL127 HEK-293T C43(0.84); C93(1.04); C138(1.00)  LDD1602  [24]
 LDCM0399  CL128 HEK-293T C43(0.86); C93(0.98); C138(0.88)  LDD1603  [24]
 LDCM0400  CL13 HCT 116 C43(0.46)  LDD0717  [9]
 LDCM0401  CL14 HCT 116 C43(0.80)  LDD0718  [9]
 LDCM0402  CL15 HCT 116 C43(0.24)  LDD0719  [9]
 LDCM0403  CL16 HCT 116 C43(0.88)  LDD0720  [9]
 LDCM0404  CL17 HCT 116 C43(0.78)  LDD0721  [9]
 LDCM0405  CL18 HCT 116 C43(0.66)  LDD0722  [9]
 LDCM0406  CL19 HCT 116 C43(0.56)  LDD0723  [9]
 LDCM0407  CL2 HCT 116 C43(0.90)  LDD0724  [9]
 LDCM0408  CL20 HCT 116 C43(0.45)  LDD0725  [9]
 LDCM0409  CL21 HCT 116 C43(0.32)  LDD0726  [9]
 LDCM0410  CL22 HCT 116 C43(0.10)  LDD0727  [9]
 LDCM0411  CL23 HCT 116 C43(0.50)  LDD0728  [9]
 LDCM0412  CL24 HCT 116 C43(0.34)  LDD0729  [9]
 LDCM0413  CL25 HCT 116 C43(0.39)  LDD0730  [9]
 LDCM0414  CL26 HCT 116 C43(0.54)  LDD0731  [9]
 LDCM0415  CL27 HCT 116 C43(0.63)  LDD0732  [9]
 LDCM0416  CL28 HCT 116 C43(0.46)  LDD0733  [9]
 LDCM0417  CL29 HCT 116 C43(0.41)  LDD0734  [9]
 LDCM0418  CL3 HCT 116 C43(1.25)  LDD0735  [9]
 LDCM0419  CL30 HCT 116 C43(0.67)  LDD0736  [9]
 LDCM0420  CL31 HCT 116 C43(0.70)  LDD0737  [9]
 LDCM0421  CL32 HCT 116 C43(0.66)  LDD0738  [9]
 LDCM0422  CL33 HCT 116 C43(0.59)  LDD0739  [9]
 LDCM0423  CL34 HCT 116 C43(0.28)  LDD0740  [9]
 LDCM0424  CL35 HCT 116 C43(0.34)  LDD0741  [9]
 LDCM0425  CL36 HCT 116 C43(0.45)  LDD0742  [9]
 LDCM0426  CL37 HCT 116 C43(0.33)  LDD0743  [9]
 LDCM0428  CL39 HCT 116 C43(0.38)  LDD0745  [9]
 LDCM0429  CL4 HCT 116 C43(0.87)  LDD0746  [9]
 LDCM0430  CL40 HCT 116 C43(0.47)  LDD0747  [9]
 LDCM0431  CL41 HCT 116 C43(0.49)  LDD0748  [9]
 LDCM0432  CL42 HCT 116 C43(0.10)  LDD0749  [9]
 LDCM0433  CL43 HCT 116 C43(0.24)  LDD0750  [9]
 LDCM0434  CL44 HCT 116 C43(0.39)  LDD0751  [9]
 LDCM0435  CL45 HCT 116 C43(0.25)  LDD0752  [9]
 LDCM0436  CL46 HCT 116 C43(1.92)  LDD0753  [9]
 LDCM0437  CL47 HCT 116 C43(1.83)  LDD0754  [9]
 LDCM0438  CL48 HCT 116 C43(2.20)  LDD0755  [9]
 LDCM0439  CL49 HCT 116 C43(1.37)  LDD0756  [9]
 LDCM0440  CL5 HCT 116 C43(0.90)  LDD0757  [9]
 LDCM0441  CL50 HCT 116 C43(1.37)  LDD0758  [9]
 LDCM0442  CL51 HCT 116 C43(1.69)  LDD0759  [9]
 LDCM0443  CL52 HCT 116 C43(1.73)  LDD0760  [9]
 LDCM0444  CL53 HCT 116 C43(1.41)  LDD0761  [9]
 LDCM0445  CL54 HCT 116 C43(1.71)  LDD0762  [9]
 LDCM0446  CL55 HCT 116 C43(1.81)  LDD0763  [9]
 LDCM0447  CL56 HCT 116 C43(1.46)  LDD0764  [9]
 LDCM0448  CL57 HCT 116 C43(1.83)  LDD0765  [9]
 LDCM0449  CL58 HCT 116 C43(1.61)  LDD0766  [9]
 LDCM0450  CL59 HCT 116 C43(1.37)  LDD0767  [9]
 LDCM0451  CL6 HCT 116 C43(0.65)  LDD0768  [9]
 LDCM0452  CL60 HCT 116 C43(1.35)  LDD0769  [9]
 LDCM0453  CL61 HEK-293T C138(0.81)  LDD1051  [9]
 LDCM0454  CL62 HEK-293T C138(0.61)  LDD1052  [9]
 LDCM0455  CL63 HEK-293T C138(0.59)  LDD1053  [9]
 LDCM0456  CL64 HEK-293T C138(0.85)  LDD1054  [9]
 LDCM0457  CL65 HEK-293T C138(0.58)  LDD1055  [9]
 LDCM0458  CL66 HEK-293T C138(0.60)  LDD1056  [9]
 LDCM0459  CL67 HEK-293T C138(0.65)  LDD1057  [9]
 LDCM0460  CL68 HEK-293T C138(0.48)  LDD1058  [9]
 LDCM0461  CL69 HEK-293T C138(0.90)  LDD1059  [9]
 LDCM0462  CL7 HCT 116 C43(0.49)  LDD0779  [9]
 LDCM0463  CL70 HEK-293T C138(0.71)  LDD1061  [9]
 LDCM0464  CL71 HEK-293T C138(0.63)  LDD1062  [9]
 LDCM0465  CL72 HEK-293T C138(0.89)  LDD1063  [9]
 LDCM0466  CL73 HEK-293T C138(0.57)  LDD1064  [9]
 LDCM0467  CL74 HEK-293T C138(0.31)  LDD1065  [9]
 LDCM0469  CL76 HCT 116 C43(0.84)  LDD0786  [9]
 LDCM0470  CL77 HCT 116 C43(0.81)  LDD0787  [9]
 LDCM0471  CL78 HCT 116 C43(0.88)  LDD0788  [9]
 LDCM0472  CL79 HCT 116 C43(0.56)  LDD0789  [9]
 LDCM0473  CL8 HCT 116 C43(0.31)  LDD0790  [9]
 LDCM0474  CL80 HCT 116 C43(1.05)  LDD0791  [9]
 LDCM0475  CL81 HCT 116 C43(0.84)  LDD0792  [9]
 LDCM0476  CL82 HCT 116 C43(0.30)  LDD0793  [9]
 LDCM0477  CL83 HCT 116 C43(0.39)  LDD0794  [9]
 LDCM0478  CL84 HCT 116 C43(0.18)  LDD0795  [9]
 LDCM0479  CL85 HCT 116 C43(0.76)  LDD0796  [9]
 LDCM0480  CL86 HCT 116 C43(1.12)  LDD0797  [9]
 LDCM0481  CL87 HCT 116 C43(0.80)  LDD0798  [9]
 LDCM0482  CL88 HCT 116 C43(0.46)  LDD0799  [9]
 LDCM0483  CL89 HCT 116 C43(0.09)  LDD0800  [9]
 LDCM0484  CL9 HCT 116 C43(0.70)  LDD0801  [9]
 LDCM0485  CL90 HCT 116 C43(0.96)  LDD0802  [9]
 LDCM0486  CL91 PaTu 8988t C138(1.53)  LDD1365  [9]
 LDCM0487  CL92 PaTu 8988t C138(1.60)  LDD1366  [9]
 LDCM0488  CL93 PaTu 8988t C138(1.47)  LDD1367  [9]
 LDCM0489  CL94 PaTu 8988t C138(3.83)  LDD1368  [9]
 LDCM0490  CL95 PaTu 8988t C138(2.35)  LDD1369  [9]
 LDCM0491  CL96 PaTu 8988t C138(1.14)  LDD1370  [9]
 LDCM0492  CL97 PaTu 8988t C138(1.22)  LDD1371  [9]
 LDCM0493  CL98 PaTu 8988t C138(1.32)  LDD1372  [9]
 LDCM0494  CL99 PaTu 8988t C138(1.36)  LDD1373  [9]
 LDCM0634  CY-0357 Hep-G2 C138(5.48)  LDD2228  [22]
 LDCM0495  E2913 HEK-293T C43(0.86); C93(1.06); C138(0.92)  LDD1698  [24]
 LDCM0625  F8 Ramos C43(7.80)  LDD2187  [25]
 LDCM0572  Fragment10 Ramos C43(0.94)  LDD2189  [25]
 LDCM0573  Fragment11 Ramos C43(0.21)  LDD2190  [25]
 LDCM0574  Fragment12 Ramos C43(0.90)  LDD2191  [25]
 LDCM0575  Fragment13 Ramos C43(0.72)  LDD2192  [25]
 LDCM0576  Fragment14 Ramos C43(0.66)  LDD2193  [25]
 LDCM0579  Fragment20 Ramos C43(0.69)  LDD2194  [25]
 LDCM0580  Fragment21 Ramos C43(0.81)  LDD2195  [25]
 LDCM0586  Fragment28 Ramos C43(0.98)  LDD2198  [25]
 LDCM0588  Fragment30 Ramos C43(2.74)  LDD2199  [25]
 LDCM0589  Fragment31 Ramos C43(2.28)  LDD2200  [25]
 LDCM0590  Fragment32 Ramos C43(1.40)  LDD2201  [25]
 LDCM0468  Fragment33 HEK-293T C138(0.40)  LDD1066  [9]
 LDCM0566  Fragment4 Ramos C43(0.53)  LDD2184  [25]
 LDCM0427  Fragment51 HCT 116 C43(0.18)  LDD0744  [9]
 LDCM0610  Fragment52 Ramos C43(0.83)  LDD2204  [25]
 LDCM0614  Fragment56 Ramos C43(1.08)  LDD2205  [25]
 LDCM0569  Fragment7 Ramos C43(0.55)  LDD2186  [25]
 LDCM0571  Fragment9 Ramos C43(1.83)  LDD2188  [25]
 LDCM0107  IAA HeLa H20(0.00); C43(0.00)  LDD0221  [8]
 LDCM0124  JWB142 DM93 Y68(0.40)  LDD0286  [7]
 LDCM0125  JWB146 DM93 Y68(1.10)  LDD0287  [7]
 LDCM0126  JWB150 DM93 Y68(20.00)  LDD0288  [7]
 LDCM0127  JWB152 DM93 Y68(6.14)  LDD0289  [7]
 LDCM0022  KB02 HEK-293T C43(1.01); C93(0.96); C138(0.82)  LDD1492  [24]
 LDCM0023  KB03 HEK-293T C43(1.05); C93(0.99); C138(0.90)  LDD1497  [24]
 LDCM0024  KB05 HMCB C93(0.95); C138(1.25)  LDD3312  [26]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C75(1.12)  LDD2102  [3]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C75(0.36)  LDD2121  [3]
 LDCM0109  NEM HeLa N.A.  LDD0223  [8]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C75(0.35)  LDD2089  [3]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C75(1.17)  LDD2092  [3]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C75(0.73)  LDD2093  [3]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C75(0.67); C43(0.27)  LDD2096  [3]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C75(0.70)  LDD2097  [3]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C75(0.90)  LDD2098  [3]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C75(0.61)  LDD2099  [3]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C75(0.34)  LDD2100  [3]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C75(0.64)  LDD2101  [3]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C75(0.35)  LDD2104  [3]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C75(1.90)  LDD2105  [3]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C75(0.28)  LDD2106  [3]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C75(0.86); C43(1.16)  LDD2107  [3]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C75(0.65); C43(0.69)  LDD2109  [3]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C75(0.45)  LDD2110  [3]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C75(0.71)  LDD2111  [3]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C75(0.65)  LDD2115  [3]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C43(0.90)  LDD2116  [3]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C75(1.29)  LDD2118  [3]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C75(0.96)  LDD2120  [3]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C75(0.90)  LDD2122  [3]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C75(0.64); C43(0.77)  LDD2123  [3]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C75(1.04)  LDD2124  [3]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C75(0.68)  LDD2125  [3]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C75(1.22); C43(0.43)  LDD2126  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C75(0.92)  LDD2127  [3]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C75(1.00)  LDD2128  [3]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C75(0.66)  LDD2133  [3]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C75(0.66)  LDD2134  [3]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C75(0.90)  LDD2135  [3]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C75(0.69)  LDD2136  [3]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C75(0.88)  LDD2137  [3]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C75(0.95)  LDD1700  [3]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C75(0.49)  LDD2140  [3]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C75(0.51)  LDD2141  [3]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C75(1.03)  LDD2143  [3]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C75(1.81)  LDD2145  [3]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C75(0.63)  LDD2146  [3]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C75(3.87)  LDD2147  [3]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C75(0.69)  LDD2148  [3]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C75(0.98)  LDD2149  [3]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C75(0.25)  LDD2150  [3]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C43(0.47)  LDD2151  [3]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C75(1.83)  LDD2153  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
E3 ubiquitin-protein ligase Arkadia (RNF111) Arkadia family Q6ZNA4
DNA (cytosine-5)-methyltransferase 3B (DNMT3B) C5-methyltransferase family Q9UBC3
Probable helicase senataxin (SETX) DNA2/NAM7 helicase family Q7Z333
Histone deacetylase 4 (HDAC4) Histone deacetylase family P56524
E3 SUMO-protein ligase ZNF451 (ZNF451) Krueppel C2H2-type zinc-finger protein family Q9Y4E5
E3 SUMO-protein ligase PIAS2 (PIAS2) PIAS family O75928
E3 SUMO-protein ligase RanBP2 (RANBP2) RanBP2 E3 ligase family P49792
RuvB-like 1 (RUVBL1) RuvB family Q9Y265
SUMO-activating enzyme subunit 2 (UBA2) Ubiquitin-activating E1 family Q9UBT2
Ubiquitin-like modifier-activating enzyme 1 (UBA1) Ubiquitin-activating E1 family P22314
Germ cell-less protein-like 1 (GMCL1) . Q96IK5
RWD domain-containing protein 3 (RWDD3) . Q9Y3V2
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Importin-13 (IPO13) Importin beta family O94829
Cellular tumor antigen p53 (TP53) P53 family P04637
Ran GTPase-activating protein 1 (RANGAP1) RNA1 family P46060
Transcription factor
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transcription factor AP-2 gamma (TFAP2C) AP-2 family Q92754
Transcription factor AP-2-alpha (TFAP2A) AP-2 family P05549
Mothers against decapentaplegic homolog 4 (SMAD4) Dwarfin/SMAD family Q13485
ETS domain-containing protein Elk-1 (ELK1) ETS family P19419
Alpha-globin transcription factor CP2 (TFCP2) Grh/CP2 family Q12800
Class E basic helix-loop-helix protein 40 (BHLHE40) . O14503
Transcription factor SOX-10 (SOX10) . P56693
Zinc finger and BTB domain-containing protein 26 (ZBTB26) . Q9HCK0
Other
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ataxin-1 (ATXN1) ATXN1 family P54253
Death domain-associated protein 6 (DAXX) DAXX family Q9UER7
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Charged multivesicular body protein 4b (CHMP4B) SNF7 family Q9H444
Small ubiquitin-related modifier 1 (SUMO1) Ubiquitin family P63165
Small ubiquitin-related modifier 2 (SUMO2) Ubiquitin family P61956
Small ubiquitin-related modifier 5 (SUMO1P1) Ubiquitin family G2XKQ0
Ectodysplasin-A receptor-associated adapter protein (EDARADD) . Q8WWZ3
Zinc finger CCHC domain-containing protein 7 (ZCCHC7) . Q8N3Z6

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
5 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
6 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
7 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
8 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
9 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
10 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
11 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
12 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
13 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
14 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
15 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
16 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
17 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
18 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
19 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
20 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
21 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
22 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
23 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
24 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
25 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
26 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840