Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0553
Competitor Name
Nucleophilic fragment 6b
Synonyms
1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-2-nitroethan-1-one
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 280.28
Lipid-water partition coefficient (xlogp) 1.2
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C13H16N2O5
IUPAC Name
1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-2-nitroethanone
Canonical SMILES
COC1=C(C=C2CN(CCC2=C1)C(=O)C[N+](=O)[O-])OC
InChI
InChI=1S/C13H16N2O5/c1-19-11-5-9-3-4-14(13(16)8-15(17)18)7-10(9)6-12(11)20-2/h5-6H,3-4,7-8H2,1-2H3
InChIKey
WCRMWKKLHLVGBI-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
BTD
 Probe Info  		5 mM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

300 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(E3-independent) E2 ubiquitin-conjugating enzyme (UBE2O) LDTP11601 0.41  LDD2147 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) LDTP02984 2.12  LDD2147 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 3.03  LDD2147 
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 2.99  LDD2147 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 3.30  LDD2147 
2-iminobutanoate/2-iminopropanoate deaminase (RIDA) LDTP04529 2.19  LDD2147 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 2.43; 0.45; 0.99  LDD2147 
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 4.21; 1.36  LDD2147 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.94  LDD2147 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 1.82  LDD2147 
26S proteasome non-ATPase regulatory subunit 4 (PSMD4) LDTP04655 1.31  LDD2147 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.85; 1.16  LDD2147 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 1.50  LDD2147 
26S proteasome regulatory subunit 6A (PSMC3) LDTP02933 4.82  LDD2147 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 0.98  LDD2147 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 1.61  LDD2147 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 2.16  LDD2147 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 3.41  LDD2147 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 2.06  LDD2147 
6-phosphogluconolactonase (PGLS) LDTP14535 3.04  LDD2147 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 2.33  LDD2147 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.85; 2.95  LDD2147 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 1.99  LDD2147 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 1.74  LDD2147 
Acyl-protein thioesterase 2 (LYPLA2) LDTP01573 1.28  LDD2147 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 1.89  LDD2147 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 2.25  LDD2147 
Adenosylhomocysteinase (AHCY) LDTP03242 1.32; 2.76; 1.15  LDD2147 
Adenylate kinase 2, mitochondrial (AK2) LDTP04636 2.27  LDD2147 
Adenylosuccinate lyase (ADSL) LDTP03551 2.93  LDD2147 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 1.43  LDD2147 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 2.97  LDD2147 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 3.64  LDD2147 
Aldehyde dehydrogenase, mitochondrial (ALDH2) LDTP02074 1.22  LDD2147 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 1.11; 0.68; 1.79 ...  LDD2147 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 0.98; 1.04  LDD2147 
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) LDTP04253 2.60  LDD2147 
Alpha-enolase (ENO1) LDTP02159 0.73; 0.91; 1.66  LDD2147 
Amidophosphoribosyltransferase (PPAT) LDTP05480 1.31  LDD2147 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 0.83  LDD2147 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 3.41  LDD2147 
Aspartyl aminopeptidase (DNPEP) LDTP13527 2.47  LDD2147 
Aspartyl/asparaginyl beta-hydroxylase (ASPH) LDTP05652 2.50  LDD2147 
ATP-citrate synthase (ACLY) LDTP04561 0.95  LDD2147 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 2.60; 1.35  LDD2147 
ATP-dependent RNA helicase A (DHX9) LDTP05550 2.51; 2.56; 1.00 ...  LDD2147 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 2.95; 2.82  LDD2147 
ATP-dependent RNA helicase DDX3Y (DDX3Y) LDTP00664 1.58; 2.47  LDD2147 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 4.83  LDD2147 
ATP-dependent RNA helicase DHX30 (DHX30) LDTP07946 3.20  LDD2147 
ATPase family AAA domain-containing protein 2 (ATAD2) LDTP07607 3.13  LDD2147 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 3.23  LDD2147 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 1.07  LDD2147 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 2.88; 0.95  LDD2147 
Bleomycin hydrolase (BLMH) LDTP05992 1.34; 1.88  LDD2147 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 2.15  LDD2147 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 1.34; 4.04; 2.41  LDD2147 
cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) LDTP02909 5.18  LDD2147 
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (CMTR1) LDTP08773 0.10  LDD2147 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 3.21  LDD2147 
Catalase (CAT) LDTP02001 1.21; 1.56  LDD2147 
Cathepsin B (CTSB) LDTP02223 1.08  LDD2147 
Cathepsin Z (CTSZ) LDTP13147 1.94  LDD2147 
CCA tRNA nucleotidyltransferase 1, mitochondrial (TRNT1) LDTP10716 0.67  LDD2147 
Choline-phosphate cytidylyltransferase A (PCYT1A) LDTP04261 2.97  LDD2147 
Citrate synthase, mitochondrial (CS) LDTP01205 3.18; 3.39  LDD2147 
CTP synthase 1 (CTPS1) LDTP02922 1.59; 2.49  LDD2147 
Cullin-1 (CUL1) LDTP05946 2.39  LDD2147 
Cullin-2 (CUL2) LDTP05947 1.51  LDD2147 
Cullin-4A (CUL4A) LDTP05949 2.59  LDD2147 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 1.13  LDD2147 
Cytoplasmic aconitate hydratase (ACO1) LDTP03110 1.92; 2.08; 1.86  LDD2147 
Cytosol aminopeptidase (LAP3) LDTP03455 2.99; 2.04  LDD2147 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 1.11  LDD2147 
D-dopachrome decarboxylase (DDT) LDTP03513 1.22  LDD2147 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 0.98  LDD2147 
Deoxyribose-phosphate aldolase (DERA) LDTP13941 0.84  LDD2147 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) LDTP03669 1.94  LDD2147 
Dipeptidyl peptidase 9 (DPP9) LDTP08198 4.02  LDD2147 
Diphosphomevalonate decarboxylase (MVD) LDTP04567 3.09  LDD2147 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 0.82  LDD2147 
DNA repair protein RAD50 (RAD50) LDTP09912 3.75  LDD2147 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 2.51; 1.03  LDD2147 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 2.58  LDD2147 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 2.38  LDD2147 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 1.08  LDD2147 
DNA topoisomerase 1 (TOP1) LDTP02567 1.53; 1.15  LDD2147 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 2.10; 1.57; 1.90 ...  LDD2147 
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) LDTP02993 0.91  LDD2147 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 4.11  LDD2147 
Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 0.59  LDD2147 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 1.38  LDD2147 
Dynamin-2 (DNM2) LDTP04374 2.28  LDD2147 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 1.01  LDD2147 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 4.99  LDD2147 
E3 ubiquitin-protein ligase Itchy homolog (ITCH) LDTP10441 0.80  LDD2147 
E3 ubiquitin-protein ligase RBX1 (RBX1) LDTP05019 3.92  LDD2147 
E3 ubiquitin-protein ligase RING1 (RING1) LDTP05496 2.00  LDD2147 
E3 ubiquitin-protein ligase RNF114 (RNF114) LDTP14083 3.62  LDD2147 
E3 ubiquitin-protein ligase SMURF2 (SMURF2) LDTP12138 1.65  LDD2147 
E3 ubiquitin-protein ligase ZFP91 (ZFP91) LDTP10481 2.40  LDD2147 
E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) LDTP06098 0.60; 0.75  LDD2147 
Egl nine homolog 1 (EGLN1) LDTP11649 2.72  LDD2147 
Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA) LDTP02694 1.38; 1.19  LDD2147 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.57  LDD2147 
Elongation factor 2 (EEF2) LDTP02672 1.03; 2.09; 2.40 ...  LDD2147 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 3.39  LDD2147 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 3.05  LDD2147 
Ephrin type-A receptor 2 (EPHA2) LDTP03474 2.01  LDD2147 
Epidermal growth factor receptor (EGFR) LDTP01785 4.15  LDD2147 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 1.32  LDD2147 
Eukaryotic translation initiation factor 2 subunit 3B (EIF2S3B) LDTP14895 1.57  LDD2147 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 4.07; 1.82; 1.13 ...  LDD2147 
Exosome complex component 10 (EXOSC10) LDTP05312 2.69  LDD2147 
Exosome complex component MTR3 (EXOSC6) LDTP07054 1.91; 2.02  LDD2147 
F-box only protein 11 (FBXO11) LDTP08361 1.92  LDD2147 
Fatty acid synthase (FASN) LDTP04243 3.48; 4.24; 2.07 ...  LDD2147 
Gamma-glutamylcyclotransferase (GGCT) LDTP01164 1.78  LDD2147 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 1.56  LDD2147 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.82  LDD2147 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 4.06  LDD2147 
Glutaredoxin-3 (GLRX3) LDTP01374 1.22  LDD2147 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 3.33; 1.78  LDD2147 
Glutathione S-transferase P (GSTP1) LDTP02333 1.64; 2.44; 1.28  LDD2147 
Glutathione synthetase (GSS) LDTP04200 1.67  LDD2147 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 2.29; 1.15; 2.22  LDD2147 
Glycine--tRNA ligase (GARS1) LDTP03946 0.71; 1.46  LDD2147 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.91; 1.05; 3.91  LDD2147 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 2.63  LDD2147 
GMP reductase 1 (GMPR) LDTP03830 1.58  LDD2147 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 2.70; 1.83  LDD2147 
GTP-binding nuclear protein Ran (RAN) LDTP05007 2.24  LDD2147 
Guanine nucleotide-binding protein-like 3 (GNL3) LDTP11297 2.13  LDD2147 
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1) LDTP01061 3.06  LDD2147 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 1.68  LDD2147 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 1.00  LDD2147 
Heme oxygenase 2 (HMOX2) LDTP03540 2.53; 3.15  LDD2147 
Hexokinase-1 (HK1) LDTP02991 1.68; 1.23  LDD2147 
Hexokinase-2 (HK2) LDTP04531 1.40  LDD2147 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 2.47; 1.19  LDD2147 
Histone deacetylase 1 (HDAC1) LDTP05918 2.38  LDD2147 
Histone PARylation factor 1 (HPF1) LDTP12743 2.40  LDD2147 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 4.92  LDD2147 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 1.15  LDD2147 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 4.13  LDD2147 
Inorganic pyrophosphatase (PPA1) LDTP14854 0.95  LDD2147 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 2.12; 3.19  LDD2147 
Inositol monophosphatase 1 (IMPA1) LDTP03470 0.79  LDD2147 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 2.19  LDD2147 
Integrin-linked protein kinase (ILK) LDTP05859 2.24  LDD2147 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 2.56  LDD2147 
Isoleucine--tRNA ligase, mitochondrial (IARS2) LDTP12588 1.81  LDD2147 
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) LDTP06006 1.80  LDD2147 
Kinesin-like protein KIF14 (KIF14) LDTP06303 1.19  LDD2147 
Kinesin-like protein KIF21A (KIF21A) LDTP08077 2.00  LDD2147 
Kinesin-like protein KIF2A (KIF2A) LDTP00188 1.64  LDD2147 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 2.99  LDD2147 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 3.20  LDD2147 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 1.53  LDD2147 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 2.51  LDD2147 
Lysine-specific demethylase 3B (KDM3B) LDTP07982 1.56; 0.39  LDD2147 
Lysosomal acid phosphatase (ACP2) LDTP02539 1.37  LDD2147 
Macrophage migration inhibitory factor (MIF) LDTP02713 3.22; 2.65  LDD2147 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 2.02; 1.22; 2.95  LDD2147 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 2.10  LDD2147 
Matrix metalloproteinase-14 (MMP14) LDTP04352 1.96  LDD2147 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 3.91  LDD2147 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 1.16  LDD2147 
Mitogen-activated protein kinase 14 (MAPK14) LDTP06547 1.90  LDD2147 
Multifunctional protein CAD (CAD) LDTP03401 2.93; 0.90; 1.61 ...  LDD2147 
MYG1 exonuclease (MYG1) LDTP12154 3.18  LDD2147 
Myosin-9 (MYH9) LDTP03764 1.08; 3.63; 0.99 ...  LDD2147 
N-acetyl-D-glucosamine kinase (NAGK) LDTP13372 3.33  LDD2147 
N-alpha-acetyltransferase 10 (NAA10) LDTP03938 4.48  LDD2147 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 1.88  LDD2147 
N-alpha-acetyltransferase 16, NatA auxiliary subunit (NAA16) LDTP07455 1.68  LDD2147 
NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10) LDTP01561 1.40  LDD2147 
NADH dehydrogenase 1 alpha subcomplex subunit 5 (NDUFA5) LDTP06614 3.24  LDD2147 
NADH dehydrogenase 1 alpha subcomplex subunit 8 (NDUFA8) LDTP04494 1.30  LDD2147 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.74; 1.21  LDD2147 
Neurolysin, mitochondrial (NLN) LDTP11494 1.74  LDD2147 
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT) LDTP06346 1.10  LDD2147 
Nitric oxide synthase-interacting protein (NOSIP) LDTP13940 1.93  LDD2147 
Nucleolar GTP-binding protein 2 (GNL2) LDTP05987 3.85  LDD2147 
Obg-like ATPase 1 (OLA1) LDTP12610 1.59  LDD2147 
Oligoribonuclease, mitochondrial (REXO2) LDTP13972 3.76  LDD2147 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 1.52  LDD2147 
Pappalysin-2 (PAPPA2) LDTP11399 3.29  LDD2147 
Parkinson disease protein 7 (PARK7) LDTP10878 1.71  LDD2147 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.27; 0.93; 0.85  LDD2147 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 1.53  LDD2147 
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) LDTP03374 2.93  LDD2147 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 1.48; 3.44; 1.75  LDD2147 
Peptidyl-prolyl cis-trans isomerase G (PPIG) LDTP05866 0.82  LDD2147 
Peroxiredoxin-1 (PRDX1) LDTP05503 9.02  LDD2147 
Peroxiredoxin-6 (PRDX6) LDTP03510 1.56  LDD2147 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 1.56  LDD2147 
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (INPPL1) LDTP00617 2.51  LDD2147 
Phosphoacetylglucosamine mutase (PGM3) LDTP01584 0.96  LDD2147 
Phosphoglucomutase-1 (PGM1) LDTP03818 2.00  LDD2147 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 1.26; 0.70  LDD2147 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 0.89  LDD2147 
Platelet-activating factor acetylhydrolase IB subunit alpha2 (PAFAH1B2) LDTP05078 1.81  LDD2147 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 2.92; 2.01; 3.66  LDD2147 
Probable ATP-dependent RNA helicase DDX17 (DDX17) LDTP09899 4.09  LDD2147 
Probable ATP-dependent RNA helicase DDX23 (DDX23) LDTP11248 2.58  LDD2147 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 4.53; 3.72  LDD2147 
Probable ATP-dependent RNA helicase DHX37 (DHX37) LDTP08625 1.57  LDD2147 
Probable cysteine--tRNA ligase, mitochondrial (CARS2) LDTP16026 1.23  LDD2147 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 1.40  LDD2147 
Probable global transcription activator SNF2L1 (SMARCA1) LDTP03442 2.46  LDD2147 
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 0.57  LDD2147 
Procollagen galactosyltransferase 1 (COLGALT1) LDTP09055 2.88  LDD2147 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) LDTP00285 3.76  LDD2147 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 3.75; 1.20  LDD2147 
Prolyl 3-hydroxylase 2 (P3H2) LDTP08504 1.27  LDD2147 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 0.93  LDD2147 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.95  LDD2147 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 2.34  LDD2147 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 1.59  LDD2147 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 2.35; 2.11  LDD2147 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 3.97  LDD2147 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 0.79; 1.02; 1.15  LDD2147 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 1.44; 1.16  LDD2147 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 1.80  LDD2147 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 3.91  LDD2147 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 1.37  LDD2147 
Protein disulfide-isomerase (P4HB) LDTP02188 5.15; 1.05  LDD2147 
Protein phosphatase 1G (PPM1G) LDTP00616 2.35; 1.83  LDD2147 
Protein PML (PML) LDTP03496 0.95  LDD2147 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 1.68; 1.76; 0.67 ...  LDD2147 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 2.66  LDD2147 
Purine nucleoside phosphorylase (PNP) LDTP01781 1.23  LDD2147 
Pyruvate kinase PKM (PKM) LDTP02733 1.03; 2.59; 0.99 ...  LDD2147 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 2.29  LDD2147 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 3.47  LDD2147 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 3.90  LDD2147 
Ras-related protein Rab-10 (RAB10) LDTP04895 1.44  LDD2147 
Ras-related protein Rab-13 (RAB13) LDTP04401 2.58  LDD2147 
Ras-related protein Rab-14 (RAB14) LDTP04901 0.94  LDD2147 
Ras-related protein Rab-1A (RAB1A) LDTP05006 3.11  LDD2147 
Ras-related protein Rab-7a (RAB7A) LDTP04399 1.73  LDD2147 
Ras-related protein Rab-8A (RAB8A) LDTP04888 3.21  LDD2147 
Regulator of nonsense transcripts 1 (UPF1) LDTP09921 2.08  LDD2147 
Replication factor C subunit 5 (RFC5) LDTP03910 2.67  LDD2147 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 3.07; 3.12  LDD2147 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 3.92; 1.24  LDD2147 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 1.31  LDD2147 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 2.53  LDD2147 
S-phase kinase-associated protein 1 (SKP1) LDTP05052 2.86; 1.70  LDD2147 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 3.86; 0.77; 1.98 ...  LDD2147 
Secernin-1 (SCRN1) LDTP05640 0.93  LDD2147 
Sepiapterin reductase (SPR) LDTP03730 2.54  LDD2147 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 2.74  LDD2147 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 8.41; 1.92; 1.66 ...  LDD2147 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 1.76  LDD2147 
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) LDTP05046 4.08  LDD2147 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 2.88; 0.94  LDD2147 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 2.17; 3.68; 1.09 ...  LDD2147 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 1.10; 1.17  LDD2147 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 0.39; 3.38; 1.87 ...  LDD2147 
Spermine synthase (SMS) LDTP04530 1.45  LDD2147 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 2.54; 3.30  LDD2147 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 2.13  LDD2147 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 1.86  LDD2147 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 2.42  LDD2147 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 1.13  LDD2147 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 2.53  LDD2147 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 3.87  LDD2147 
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) LDTP00931 3.63  LDD2147 
Telomerase RNA component interacting RNase (TRIR) LDTP11055 3.15  LDD2147 
Thimet oligopeptidase (THOP1) LDTP04542 3.09  LDD2147 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 3.74  LDD2147 
Thymidylate kinase (DTYMK) LDTP03258 1.67  LDD2147 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 1.08  LDD2147 
Transforming protein RhoA (RHOA) LDTP04927 3.64; 1.82  LDD2147 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 1.70; 2.48; 1.05  LDD2147 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 2.37  LDD2147 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 4.28  LDD2147 
Triosephosphate isomerase (TPI1) LDTP04851 2.29; 1.11; 2.05 ...  LDD2147 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 1.94  LDD2147 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 3.08; 1.67  LDD2147 
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) LDTP05475 2.28  LDD2147 
Tyrosine-protein phosphatase non-receptor type 14 (PTPN14) LDTP06443 2.18  LDD2147 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 2.71  LDD2147 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 1.11  LDD2147 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 3.06; 3.86  LDD2147 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 2.29  LDD2147 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 2.48; 1.14; 3.37  LDD2147 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 3.65  LDD2147 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 1.66  LDD2147 
UMP-CMP kinase (CMPK1) LDTP03519 4.13  LDD2147 
Unconventional myosin-Ie (MYO1E) LDTP05708 3.88  LDD2147 
Unconventional myosin-IXb (MYO9B) LDTP05879 3.14  LDD2147 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 3.22  LDD2147 
Vacuolar protein sorting-associated protein 4B (VPS4B) LDTP01186 1.17  LDD2147 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 1.18  LDD2147 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 2.67  LDD2147 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 2.06  LDD2147 
Xaa-Pro dipeptidase (PEPD) LDTP02639 1.39  LDD2147 
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⏷ Show the Full List of 300 Enzyme
92 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein theta (YWHAQ) LDTP03385 2.93; 2.95  LDD2147 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 3.05  LDD2147 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 1.23  LDD2147 
Annexin A6 (ANXA6) LDTP02247 4.19; 0.26  LDD2147 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 1.09  LDD2147 
AP-2 complex subunit beta (AP2B1) LDTP05038 3.56; 1.47; 3.67  LDD2147 
AP-2 complex subunit mu (AP2M1) LDTP10190 1.39; 1.05  LDD2147 
AP-3 complex subunit delta-1 (AP3D1) LDTP00383 2.78  LDD2147 
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) LDTP13490 2.72; 1.58  LDD2147 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 1.41  LDD2147 
Calreticulin (CALR) LDTP03402 3.08  LDD2147 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 1.34  LDD2147 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 0.94; 2.00  LDD2147 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 5.87  LDD2147 
Clathrin heavy chain 1 (CLTC) LDTP05252 1.38; 2.14; 2.22 ...  LDD2147 
Copine-3 (CPNE3) LDTP01133 1.30  LDD2147 
Cysteine-rich motor neuron 1 protein (CRIM1) LDTP12942 2.65  LDD2147 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 2.49  LDD2147 
Dysferlin (DYSF) LDTP01355 3.37; 2.41  LDD2147 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 3.83  LDD2147 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 2.49  LDD2147 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 1.96  LDD2147 
Exportin-1 (XPO1) LDTP00501 1.37; 4.90; 1.61  LDD2147 
Exportin-2 (CSE1L) LDTP04662 2.53; 2.98; 3.63 ...  LDD2147 
Fatty acid-binding protein 5 (FABP5) LDTP05292 2.48; 2.93; 1.84 ...  LDD2147 
Filamin-A (FLNA) LDTP03107 1.71; 2.97; 2.03 ...  LDD2147 
Filamin-B (FLNB) LDTP01197 2.60; 1.35; 2.04 ...  LDD2147 
Filamin-C (FLNC) LDTP06103 2.81; 3.63; 1.43 ...  LDD2147 
Galectin-3 (LGALS3) LDTP02929 6.54  LDD2147 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 1.45; 1.88  LDD2147 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 1.57; 3.00  LDD2147 
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (GNAS) LDTP05040 2.11  LDD2147 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 3.21; 1.49  LDD2147 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 4.16; 3.01  LDD2147 
Importin subunit alpha-7 (KPNA6) LDTP01031 1.51  LDD2147 
Importin subunit beta-1 (KPNB1) LDTP06242 2.24  LDD2147 
Importin-4 (IPO4) LDTP09515 1.30  LDD2147 
Importin-5 (IPO5) LDTP00266 2.60; 2.26; 2.77  LDD2147 
Importin-7 (IPO7) LDTP01574 2.95  LDD2147 
Importin-9 (IPO9) LDTP10663 2.14; 0.60  LDD2147 
Integrin alpha-6 (ITGA6) LDTP03211 0.89  LDD2147 
Kinesin-1 heavy chain (KIF5B) LDTP03664 3.14; 5.08  LDD2147 
LETM1 domain-containing protein LETM2, mitochondrial (LETM2) LDTP14898 1.98  LDD2147 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 1.98  LDD2147 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 1.95  LDD2147 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 3.27; 4.67; 1.57  LDD2147 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 1.32  LDD2147 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 0.60  LDD2147 
Myoferlin (MYOF) LDTP12916 2.42; 1.72; 2.85 ...  LDD2147 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 2.59; 2.26; 3.14  LDD2147 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 4.74  LDD2147 
Nuclear pore complex protein Nup50 (NUP50) LDTP13498 1.78  LDD2147 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 1.21  LDD2147 
Nucleoporin p58/p45 (NUP58) LDTP11293 1.55  LDD2147 
Nucleoprotein TPR (TPR) LDTP02612 3.43; 5.79  LDD2147 
Optineurin (OPTN) LDTP10189 4.23  LDD2147 
Phospholipid transfer protein C2CD2L (C2CD2L) LDTP00360 2.87  LDD2147 
Phosphorylated adapter RNA export protein (PHAX) LDTP12043 0.78  LDD2147 
Pinin (PNN) LDTP11855 1.94  LDD2147 
Podocalyxin (PODXL) LDTP00321 3.77  LDD2147 
Prohibitin 1 (PHB1) LDTP03717 2.42  LDD2147 
Protein S100-A10 (S100A10) LDTP04885 3.42  LDD2147 
Protein transport protein Sec31A (SEC31A) LDTP01478 1.67  LDD2147 
Protein transport protein Sec61 subunit beta (SEC61B) LDTP04866 4.85  LDD2147 
Protein transport protein Sec61 subunit gamma (SEC61G) LDTP04850 7.24  LDD2147 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 2.28; 0.81  LDD2147 
Serine incorporator 3 (SERINC3) LDTP05913 1.01  LDD2147 
Serine/arginine repetitive matrix protein 1 (SRRM1) LDTP08637 1.95  LDD2147 
Signal recognition particle 14 kDa protein (SRP14) LDTP03837 2.73  LDD2147 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 1.40  LDD2147 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 2.95; 1.71  LDD2147 
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) LDTP02068 2.80  LDD2147 
Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) LDTP04624 2.54  LDD2147 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 1.20  LDD2147 
Sorting nexin-12 (SNX12) LDTP13634 2.55  LDD2147 
Sorting nexin-7 (SNX7) LDTP13660 0.56  LDD2147 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 2.48  LDD2147 
T-complex protein 1 subunit delta (CCT4) LDTP04391 2.73; 3.02  LDD2147 
Talin-1 (TLN1) LDTP14031 4.07; 3.75; 1.25 ...  LDD2147 
TBC1 domain family member 4 (TBC1D4) LDTP00958 2.42  LDD2147 
THO complex subunit 1 (THOC1) LDTP10317 1.27  LDD2147 
THO complex subunit 2 (THOC2) LDTP09279 3.69  LDD2147 
THO complex subunit 7 homolog (THOC7) LDTP07397 1.55  LDD2147 
Transferrin receptor protein 1 (TFRC) LDTP01969 2.66  LDD2147 
Translocation protein SEC62 (SEC62) LDTP15838 3.81  LDD2147 
Translocation protein SEC63 homolog (SEC63) LDTP13243 1.99  LDD2147 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 2.76  LDD2147 
Transportin-3 (TNPO3) LDTP14133 1.77  LDD2147 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 1.68  LDD2147 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 1.38; 1.89  LDD2147 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 3.36  LDD2147 
Vesicle-associated membrane protein-associated protein B/C (VAPB) LDTP01556 1.77  LDD2147 
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⏷ Show the Full List of 92 Transporter and channel
15 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Cell division cycle 5-like protein (CDC5L) LDTP10868 0.48  LDD2147 
Core-binding factor subunit beta (CBFB) LDTP06012 1.98  LDD2147 
Dr1-associated corepressor (DRAP1) LDTP06229 2.97  LDD2147 
eIF5-mimic protein 1 (BZW2) LDTP14241 2.88  LDD2147 
Forkhead box protein K1 (FOXK1) LDTP05201 1.08  LDD2147 
Gamma-interferon-inducible protein 16 (IFI16) LDTP06602 0.64  LDD2147 
General transcription factor II-I (GTF2I) LDTP05101 1.54  LDD2147 
High mobility group protein B1 (HMGB1) LDTP02343 3.67  LDD2147 
Interferon regulatory factor 3 (IRF3) LDTP06168 1.30  LDD2147 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 2.25  LDD2147 
PHD finger-like domain-containing protein 5A (PHF5A) LDTP08006 2.15  LDD2147 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 1.05  LDD2147 
Transcription factor A, mitochondrial (TFAM) LDTP05235 2.80  LDD2147 
Transcription factor YY2 (YY2) LDTP00626 0.28  LDD2147 
Transcriptional activator protein Pur-alpha (PURA) LDTP05248 1.26  LDD2147 
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⏷ Show the Full List of 15 Transcription factor
1 GPCR Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Adhesion G-protein coupled receptor G1 (ADGRG1) LDTP14207 1.49  LDD2147 
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2 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CD166 antigen (ALCAM) LDTP05973 0.60; 1.37  LDD2147 
Intercellular adhesion molecule 1 (ICAM1) LDTP02106 0.58  LDD2147 
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2 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Endoglin (ENG) LDTP02923 2.35; 1.35  LDD2147 
Interleukin-8 (CXCL8) LDTP02477 0.31  LDD2147 
------------------------------------------------------------------------------------
323 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 1.92; 1.61  LDD2147 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 2.90  LDD2147 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 2.97; 3.29  LDD2147 
Actin-related protein 2 (ACTR2) LDTP04903 2.12; 0.90  LDD2147 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 5.44  LDD2147 
Actin-related protein T1 (ACTRT1) LDTP09433 1.09  LDD2147 
Active regulator of SIRT1 (RPS19BP1) LDTP08345 1.14  LDD2147 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 1.84; 1.80; 3.48 ...  LDD2147 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 0.92  LDD2147 
Alpha-centractin (ACTR1A) LDTP04904 0.89  LDD2147 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 0.69  LDD2147 
Annexin A7 (ANXA7) LDTP03030 1.99  LDD2147 
Armadillo repeat-containing protein 6 (ARMC6) LDTP15101 1.21  LDD2147 
Astrocytic phosphoprotein PEA-15 (PEA15) LDTP06323 4.50  LDD2147 
Barrier-to-autointegration factor (BANF1) LDTP01250 2.29; 1.65  LDD2147 
Bcl-2-associated transcription factor 1 (BCLAF1) LDTP12826 3.13  LDD2147 
Beta-soluble NSF attachment protein (NAPB) LDTP11744 3.89  LDD2147 
BRCA2 and CDKN1A-interacting protein (BCCIP) LDTP13030 2.52  LDD2147 
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) LDTP12518 1.11  LDD2147 
Calcium homeostasis endoplasmic reticulum protein (CHERP) LDTP08570 1.79  LDD2147 
Calmegin (CLGN) LDTP00493 3.29  LDD2147 
Calpain small subunit 1 (CAPNS1) LDTP02047 1.81  LDD2147 
Calponin-2 (CNN2) LDTP10864 0.89  LDD2147 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 2.61; 4.99  LDD2147 
Caprin-1 (CAPRIN1) LDTP06121 4.20  LDD2147 
Caspase activity and apoptosis inhibitor 1 (CAAP1) LDTP18416 1.29  LDD2147 
Catenin alpha-1 (CTNNA1) LDTP03711 1.92; 1.02  LDD2147 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 2.11; 1.91; 1.58 ...  LDD2147 
CD59 glycoprotein (CD59) LDTP02704 1.00  LDD2147 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 1.55  LDD2147 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 2.25  LDD2147 
Centrosomal protein of 170 kDa (CEP170) LDTP07071 2.82  LDD2147 
Centrosomal protein of 55 kDa (CEP55) LDTP06886 4.44  LDD2147 
Charged multivesicular body protein 1b (CHMP1B) LDTP07984 8.79  LDD2147 
Charged multivesicular body protein 5 (CHMP5) LDTP12948 1.10  LDD2147 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 3.52; 4.95  LDD2147 
Cleavage stimulation factor subunit 1 (CSTF1) LDTP14812 1.25  LDD2147 
CLIP-associating protein 2 (CLASP2) LDTP01129 0.64  LDD2147 
Clustered mitochondria protein homolog (CLUH) LDTP14486 1.94  LDD2147 
Coactosin-like protein (COTL1) LDTP06024 3.26  LDD2147 
Coatomer subunit alpha (COPA) LDTP04571 2.13; 2.25  LDD2147 
Coatomer subunit beta (COPB1) LDTP04570 3.21; 1.91; 1.56  LDD2147 
Coatomer subunit delta (ARCN1) LDTP04181 0.92; 1.62  LDD2147 
Cofilin-1 (CFL1) LDTP03244 6.88; 0.92; 1.97 ...  LDD2147 
Cofilin-2 (CFL2) LDTP13827 1.90; 2.13  LDD2147 
Coiled-coil domain-containing protein 15 (CCDC15) LDTP19222 3.87  LDD2147 
Complement decay-accelerating factor (CD55) LDTP02253 0.58  LDD2147 
Condensin complex subunit 1 (NCAPD2) LDTP06281 4.25; 1.64  LDD2147 
Condensin complex subunit 3 (NCAPG) LDTP11040 2.03  LDD2147 
COP9 signalosome complex subunit 1 (GPS1) LDTP05746 1.05  LDD2147 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 0.91  LDD2147 
Coronin-1B (CORO1B) LDTP11101 2.99; 0.95; 3.94  LDD2147 
Coronin-1C (CORO1C) LDTP13580 1.85; 2.80; 3.65 ...  LDD2147 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 3.25  LDD2147 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 2.21; 1.44; 2.08 ...  LDD2147 
Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 2.28; 6.23  LDD2147 
DAZ-associated protein 1 (DAZAP1) LDTP10271 3.70  LDD2147 
Destrin (DSTN) LDTP04887 0.35; 1.16; 1.80 ...  LDD2147 
DNA damage-binding protein 1 (DDB1) LDTP06543 2.02  LDD2147 
DNA fragmentation factor subunit alpha (DFFA) LDTP00239 2.28; 2.60  LDD2147 
DNA mismatch repair protein Msh2 (MSH2) LDTP04028 1.59  LDD2147 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 1.58; 3.22  LDD2147 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 1.78; 0.60  LDD2147 
DnaJ homolog subfamily C member 7 (DNAJC7) LDTP10920 1.30; 1.98  LDD2147 
Drebrin (DBN1) LDTP06588 3.38  LDD2147 
Dynactin subunit 1 (DCTN1) LDTP06082 2.68  LDD2147 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.90  LDD2147 
Early endosome antigen 1 (EEA1) LDTP06310 3.38; 3.51  LDD2147 
Elongation factor 1-beta (EEF1B2) LDTP03283 1.56  LDD2147 
Elongation factor 1-gamma (EEF1G) LDTP03367 0.92  LDD2147 
Elongin-B (ELOB) LDTP06369 3.11  LDD2147 
Endoplasmin (HSP90B1) LDTP02734 5.28  LDD2147 
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2) LDTP11998 1.68  LDD2147 
Epsin-1 (EPN1) LDTP14256 4.34  LDD2147 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 4.31; 1.25; 2.63 ...  LDD2147 
Eukaryotic translation initiation factor 2A (EIF2A) LDTP11436 3.35  LDD2147 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 3.44; 2.18; 2.05  LDD2147 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 1.14  LDD2147 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 1.90  LDD2147 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 2.94  LDD2147 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 1.18  LDD2147 
Eukaryotic translation initiation factor 3 subunit K (EIF3K) LDTP13143 1.66  LDD2147 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 1.27  LDD2147 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 2.01  LDD2147 
Eukaryotic translation initiation factor 6 (EIF6) LDTP04743 1.27  LDD2147 
Exosome complex component RRP40 (EXOSC3) LDTP12434 0.83  LDD2147 
F-BAR domain only protein 2 (FCHO2) LDTP05605 0.96  LDD2147 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 2.62  LDD2147 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 2.54; 4.16  LDD2147 
Far upstream element-binding protein 3 (FUBP3) LDTP10408 3.40; 2.12  LDD2147 
GA-binding protein subunit beta-1 (GABPB1) LDTP05495 0.37  LDD2147 
Galectin-1 (LGALS1) LDTP02341 2.25; 1.91; 0.67 ...  LDD2147 
Gephyrin (GPHN) LDTP12448 1.76  LDD2147 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 4.84  LDD2147 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 1.57  LDD2147 
Heat shock protein 105 kDa (HSPH1) LDTP09811 1.65; 3.03; 1.22  LDD2147 
Hepatoma-derived growth factor (HDGF) LDTP04483 1.55; 2.34  LDD2147 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 2.97  LDD2147 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 2.28  LDD2147 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 2.49  LDD2147 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 3.41  LDD2147 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 2.78  LDD2147 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 2.41  LDD2147 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.01; 1.57; 0.77  LDD2147 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 2.52; 2.46; 1.83 ...  LDD2147 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 1.43; 1.17; 3.06 ...  LDD2147 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 2.63  LDD2147 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 4.31; 0.92; 1.25 ...  LDD2147 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 2.01  LDD2147 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 1.37  LDD2147 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 0.93  LDD2147 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 2.39  LDD2147 
Histone-binding protein RBBP4 (RBBP4) LDTP05590 2.09  LDD2147 
Integrin alpha-3 (ITGA3) LDTP03342 0.32  LDD2147 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 0.89; 3.42  LDD2147 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 0.71  LDD2147 
Kinesin light chain 1 (KLC1) LDTP05533 1.42  LDD2147 
Kinesin light chain 2 (KLC2) LDTP11695 2.45  LDD2147 
Lamin-B1 (LMNB1) LDTP03065 1.86  LDD2147 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 2.93; 2.15; 0.64  LDD2147 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 3.09  LDD2147 
Large ribosomal subunit protein eL15 (RPL15) LDTP04919 1.84  LDD2147 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 0.95; 1.82  LDD2147 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 2.78; 1.03  LDD2147 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 3.22  LDD2147 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 1.41  LDD2147 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 1.23  LDD2147 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 3.52; 2.20; 2.02  LDD2147 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 1.34  LDD2147 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 2.30  LDD2147 
Large ribosomal subunit protein eL8 (RPL7A) LDTP04990 1.36  LDD2147 
Large ribosomal subunit protein mL50 (MRPL50) LDTP15429 1.67  LDD2147 
Large ribosomal subunit protein mL53 (MRPL53) LDTP10266 1.76  LDD2147 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 1.37  LDD2147 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 2.92  LDD2147 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 1.29; 2.01  LDD2147 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 2.22  LDD2147 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 1.48  LDD2147 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 1.97; 0.46; 1.60 ...  LDD2147 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 1.07; 1.95  LDD2147 
Large ribosomal subunit protein uL5 (RPL11) LDTP05026 0.98; 2.75  LDD2147 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 3.54  LDD2147 
LEM domain-containing protein 2 (LEMD2) LDTP09082 0.95  LDD2147 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 2.19; 2.45; 2.28 ...  LDD2147 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 0.95; 1.11; 1.94  LDD2147 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 2.55  LDD2147 
Matrin-3 (MATR3) LDTP04027 1.39; 0.90  LDD2147 
Mediator of DNA damage checkpoint protein 1 (MDC1) LDTP06176 1.81  LDD2147 
Mesencephalic astrocyte-derived neurotrophic factor (MANF) LDTP04676 3.19  LDD2147 
Metallothionein-1H (MT1H) LDTP14783 1.67; 0.52  LDD2147 
Metallothionein-1X (MT1X) LDTP05159 1.76; 0.54  LDD2147 
Methylosome protein WDR77 (WDR77) LDTP11066 1.94  LDD2147 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 2.91; 0.98  LDD2147 
Microtubule-associated protein 4 (MAP4) LDTP03404 1.17; 3.26  LDD2147 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 1.03; 1.60  LDD2147 
Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) LDTP14136 0.47  LDD2147 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.26  LDD2147 
Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1) LDTP14239 1.62  LDD2147 
Muscleblind-like protein 1 (MBNL1) LDTP12478 0.33; 2.55  LDD2147 
NEDD8 ultimate buster 1 (NUB1) LDTP14104 1.92  LDD2147 
Neurabin-2 (PPP1R9B) LDTP10808 1.60  LDD2147 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 2.24; 3.22  LDD2147 
NHP2-like protein 1 (SNU13) LDTP04708 1.63  LDD2147 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 2.59  LDD2147 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 1.19; 1.67  LDD2147 
Nuclear receptor 2C2-associated protein (NR2C2AP) LDTP08338 1.60  LDD2147 
Nucleolar protein 16 (NOP16) LDTP16278 2.45  LDD2147 
Nucleolar protein 56 (NOP56) LDTP00313 2.25  LDD2147 
Nucleolin (NCL) LDTP02990 5.02  LDD2147 
Nucleophosmin (NPM1) LDTP02164 0.99  LDD2147 
OCIA domain-containing protein 2 (OCIAD2) LDTP17157 1.82  LDD2147 
Ovarian cancer-related protein 1 (OCR1) LDTP20391 5.36  LDD2147 
PDZ domain-containing protein GIPC1 (GIPC1) LDTP00472 1.56  LDD2147 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 5.08  LDD2147 
Plastin-2 (LCP1) LDTP02691 2.60; 1.66; 3.15 ...  LDD2147 
Pleckstrin homology domain-containing family O member 2 (PLEKHO2) LDTP18061 1.73  LDD2147 
Pleckstrin homology-like domain family B member 2 (PHLDB2) LDTP08172 3.46  LDD2147 
Plectin (PLEC) LDTP06330 2.09; 2.64; 1.38 ...  LDD2147 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 2.05; 1.95  LDD2147 
Poly(rC)-binding protein 3 (PCBP3) LDTP04793 1.00; 1.89  LDD2147 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 0.96  LDD2147 
Pre-mRNA-processing factor 6 (PRPF6) LDTP01456 2.59  LDD2147 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 1.42; 4.33  LDD2147 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 2.13  LDD2147 
Pre-mRNA-splicing factor ISY1 homolog (ISY1) LDTP13570 2.51  LDD2147 
Prelamin-A/C (LMNA) LDTP01932 2.09  LDD2147 
Probable rRNA-processing protein EBP2 (EBNA1BP2) LDTP10993 1.50  LDD2147 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 1.14  LDD2147 
Proliferating cell nuclear antigen (PCNA) LDTP02596 2.15  LDD2147 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 1.45  LDD2147 
Proteasomal ubiquitin receptor ADRM1 (ADRM1) LDTP06514 0.72  LDD2147 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 2.63; 3.10  LDD2147 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 3.17  LDD2147 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 1.49  LDD2147 
Protein FAM98A (FAM98A) LDTP09086 5.46  LDD2147 
Protein flightless-1 homolog (FLII) LDTP05734 2.31  LDD2147 
Protein IWS1 homolog (IWS1) LDTP10822 2.88  LDD2147 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 2.87  LDD2147 
Protein LSM12 (LSM12) LDTP06780 2.98  LDD2147 
Protein LTV1 homolog (LTV1) LDTP15727 1.58  LDD2147 
Protein MIS12 homolog (MIS12) LDTP11685 0.33  LDD2147 
Protein MON2 homolog (MON2) LDTP08041 4.99  LDD2147 
Protein Niban 1 (NIBAN1) LDTP11559 2.82  LDD2147 
Protein Niban 2 (NIBAN2) LDTP10847 2.23; 2.11; 4.06  LDD2147 
Protein PRRC2C (PRRC2C) LDTP14085 3.28; 2.52  LDD2147 
Protein RRP5 homolog (PDCD11) LDTP06186 0.95  LDD2147 
Protein THEM6 (THEM6) LDTP19831 1.71  LDD2147 
Protein unc-13 homolog D (UNC13D) LDTP07888 1.08  LDD2147 
Protein unc-45 homolog A (UNC45A) LDTP11890 0.92; 0.93  LDD2147 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 4.08; 0.77; 1.68  LDD2147 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.88  LDD2147 
Raftlin (RFTN1) LDTP06193 3.28  LDD2147 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 0.53  LDD2147 
Replication protein A 32 kDa subunit (RPA2) LDTP02816 3.12  LDD2147 
Replication termination factor 2 (RTF2) LDTP11434 1.81; 0.70  LDD2147 
Reticulon-4 (RTN4) LDTP12412 2.44  LDD2147 
Retinoblastoma-binding protein 5 (RBBP5) LDTP06351 2.23  LDD2147 
Rho GTPase-activating protein 18 (ARHGAP18) LDTP08822 1.68  LDD2147 
Ribonuclease inhibitor (RNH1) LDTP02656 2.48; 1.90  LDD2147 
Ribosomal L1 domain-containing protein 1 (RSL1D1) LDTP01379 1.52; 2.99  LDD2147 
Ribosomal protein eS27-like (RPS27L) LDTP07909 1.69  LDD2147 
Ribosomal protein uL16-like (RPL10L) LDTP10525 1.53; 1.45  LDD2147 
Ribosomal RNA processing protein 1 homolog A (RRP1) LDTP04729 3.69  LDD2147 
Ribosome biogenesis protein BOP1 (BOP1) LDTP06046 2.35  LDD2147 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 1.24  LDD2147 
Ribosome maturation protein SBDS (SBDS) LDTP13966 0.98  LDD2147 
RNA transcription, translation and transport factor protein (RTRAF) LDTP13782 3.00  LDD2147 
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) LDTP03495 5.37  LDD2147 
RNA-binding protein 14 (RBM14) LDTP10684 2.87  LDD2147 
RNA-binding protein 24 (RBM24) LDTP11351 0.76  LDD2147 
RNA-binding protein FUS (FUS) LDTP03775 2.09; 1.62  LDD2147 
RNA-binding protein FXR1 (FXR1) LDTP04395 2.37  LDD2147 
RNA-binding protein Raly (RALY) LDTP13467 3.03  LDD2147 
RNA-binding protein RO60 (RO60) LDTP02480 1.86  LDD2147 
Scaffold attachment factor B1 (SAFB) LDTP06385 6.94  LDD2147 
Semaphorin-4B (SEMA4B) LDTP12382 0.48  LDD2147 
Sequestosome-1 (SQSTM1) LDTP05898 3.39  LDD2147 
Serine-threonine kinase receptor-associated protein (STRAP) LDTP13991 0.60  LDD2147 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 0.84; 1.86  LDD2147 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 3.59  LDD2147 
Serine/arginine-rich splicing factor 11 (SRSF11) LDTP05458 6.76  LDD2147 
Serine/arginine-rich splicing factor 3 (SRSF3) LDTP05197 1.40; 2.32  LDD2147 
SERPINE1 mRNA-binding protein 1 (SERBP1) LDTP09081 1.91  LDD2147 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 1.34; 3.44  LDD2147 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 1.82  LDD2147 
Signal transducing adapter molecule 2 (STAM2) LDTP01339 1.31  LDD2147 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 1.47; 4.58  LDD2147 
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) LDTP04983 1.38  LDD2147 
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) LDTP02741 1.23; 1.90  LDD2147 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.64; 1.63; 1.01  LDD2147 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 1.41; 2.37; 0.84  LDD2147 
Small ribosomal subunit protein eS17 (RPS17) LDTP02302 1.60  LDD2147 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 4.32; 1.20  LDD2147 
Small ribosomal subunit protein eS25 (RPS25) LDTP05013 3.20  LDD2147 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 1.81; 1.35  LDD2147 
Small ribosomal subunit protein eS28 (RPS28) LDTP05015 6.77  LDD2147 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 2.51; 1.94  LDD2147 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 2.52  LDD2147 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 5.42; 1.51  LDD2147 
Small ribosomal subunit protein mS27 (MRPS27) LDTP09793 3.85  LDD2147 
Small ribosomal subunit protein mS35 (MRPS35) LDTP14788 4.97  LDD2147 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 4.39; 0.97  LDD2147 
Small ribosomal subunit protein uS14 (RPS29) LDTP04973 0.77  LDD2147 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 2.35  LDD2147 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.26; 1.56; 0.39  LDD2147 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 3.17  LDD2147 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 1.85  LDD2147 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 3.12  LDD2147 
Small ubiquitin-related modifier 1 (SUMO1) LDTP05048 1.53  LDD2147 
Splicing factor 1 (SF1) LDTP06429 5.99  LDD2147 
Splicing factor 3A subunit 1 (SF3A1) LDTP06393 2.15  LDD2147 
Splicing factor 3A subunit 2 (SF3A2) LDTP06387 1.28  LDD2147 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 2.56  LDD2147 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 2.94; 1.88  LDD2147 
Splicing factor U2AF 35 kDa subunit (U2AF1) LDTP05272 1.46  LDD2147 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 1.00; 2.47  LDD2147 
SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) LDTP11645 1.85  LDD2147 
Src substrate cortactin (CTTN) LDTP06094 3.30; 3.65  LDD2147 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 2.48; 2.95  LDD2147 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 3.17; 3.73; 2.77  LDD2147 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 2.27; 2.77; 3.56 ...  LDD2147 
Striatin-4 (STRN4) LDTP12519 1.09; 1.48  LDD2147 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 3.12; 4.16  LDD2147 
Suppressor of SWI4 1 homolog (PPAN) LDTP12396 3.26  LDD2147 
Survival of motor neuron-related-splicing factor 30 (SMNDC1) LDTP01362 3.42  LDD2147 
Synembryn-A (RIC8A) LDTP12381 1.75  LDD2147 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 1.32  LDD2147 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.35; 1.61; 1.19 ...  LDD2147 
T-complex protein 1 subunit eta (CCT7) LDTP10990 1.52; 0.63  LDD2147 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 2.19; 1.04  LDD2147 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 5.05; 3.11  LDD2147 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 1.54  LDD2147 
Tetratricopeptide repeat protein 39C (TTC39C) LDTP17713 3.00  LDD2147 
Transgelin-2 (TAGLN2) LDTP03846 3.28  LDD2147 
Translation initiation factor eIF2B subunit alpha (EIF2B1) LDTP06088 0.99; 3.52  LDD2147 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 1.21  LDD2147 
Translationally-controlled tumor protein (TPT1) LDTP02683 3.10; 1.97  LDD2147 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 1.33  LDD2147 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 1.19  LDD2147 
Tubulin beta-6 chain (TUBB6) LDTP11233 3.03  LDD2147 
Tubulin-folding cofactor B (TBCB) LDTP10860 4.65  LDD2147 
Tubulin-specific chaperone A (TBCA) LDTP01184 1.84  LDD2147 
Tubulin-specific chaperone E (TBCE) LDTP06479 0.31  LDD2147 
Tumor protein D54 (TPD52L2) LDTP00759 4.18  LDD2147 
Twinfilin-2 (TWF2) LDTP07404 2.14  LDD2147 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 3.73  LDD2147 
U2 snRNP-associated SURP motif-containing protein (U2SURP) LDTP00517 2.28  LDD2147 
U3 small nucleolar ribonucleoprotein protein MPP10 (MPHOSPH10) LDTP00312 1.28  LDD2147 
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31) LDTP09671 2.92  LDD2147 
U6 snRNA-associated Sm-like protein LSm4 (LSM4) LDTP14081 1.08  LDD2147 
U6 snRNA-associated Sm-like protein LSm7 (LSM7) LDTP13425 1.05  LDD2147 
Ubiquitin-like protein 5 (UBL5) LDTP11545 3.38  LDD2147 
Ubiquitin-ribosomal protein eL40 fusion protein (UBA52) LDTP05034 1.88  LDD2147 
UPF0688 protein C1orf174 (C1orf174) LDTP17648 0.94  LDD2147 
Urokinase plasminogen activator surface receptor (PLAUR) LDTP05404 0.51  LDD2147 
Vimentin (VIM) LDTP02297 2.71  LDD2147 
Vinculin (VCL) LDTP02946 3.05; 2.07; 4.00 ...  LDD2147 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 3.37  LDD2147 
WD repeat-containing protein 1 (WDR1) LDTP01118 0.73; 1.28; 1.25  LDD2147 
WD repeat-containing protein 43 (WDR43) LDTP06305 1.07  LDD2147 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 2.45; 0.47  LDD2147 
Zinc finger protein 185 (ZNF185) LDTP00580 3.00; 6.98  LDD2147 
Zinc finger RNA-binding protein (ZFR) LDTP15762 1.85  LDD2147 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 5 mM
Quantitative Method Isotope tag
Experimemt Name ISO-TOP ABPP
Competitor Name Nucleophilic fragment 6b
Competitor Concentration 0.5 mM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD2147  Download The Altas

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761