Details of the Target

General Information of Target

Target ID LDTP04306
Target Name Adenosine 5'-monophosphoramidase HINT1 (HINT1)
Gene Name HINT1
Gene ID 3094
Synonyms
HINT; PKCI1; PRKCNH1; Adenosine 5'-monophosphoramidase HINT1; EC 3.9.1.-; Desumoylating isopeptidase HINT1; EC 3.4.22.-; Histidine triad nucleotide-binding protein 1; Protein kinase C inhibitor 1; Protein kinase C-interacting protein 1; PKCI-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI
SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ
MHWPPG
Target Bioclass
Enzyme
Family
HINT family
Subcellular location
Cytoplasm
Function
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Hydrolyzes 3-indolepropionic acyl-adenylate, tryptamine adenosine phosphoramidate monoester and other fluorogenic purine nucleoside tryptamine phosphoramidates in vitro . Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. Also exhibits SUMO-specific isopeptidase activity, deconjugating SUMO1 from RGS17. Deconjugates SUMO1 from RANGAP1.
Uniprot ID
P49773
Ensemble ID
ENST00000304043.10
HGNC ID
HGNC:4912
ChEMBL ID
CHEMBL5878

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 36 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C-Sul
 Probe Info  		2.93  LDD0066  [1]
TH214
 Probe Info  		Y94(16.22)  LDD0258  [2]
ONAyne
 Probe Info  		K21(4.34)  LDD0274  [3]
STPyne
 Probe Info  		K21(9.72); K30(2.62); K83(5.56); K92(1.08)  LDD0277  [3]
BTD
 Probe Info  		C84(4.12)  LDD1699  [4]
AZ-9
 Probe Info  		D87(0.93)  LDD2208  [5]
OPA-S-S-alkyne
 Probe Info  		K30(1.48)  LDD3494  [6]
HHS-475
 Probe Info  		Y109(0.83)  LDD0264  [7]
HHS-465
 Probe Info  		Y109(8.47)  LDD2237  [8]
Acrolein
 Probe Info  		N.A.  LDD0222  [9]
DBIA
 Probe Info  		C84(0.97); C38(0.92)  LDD0078  [10]
5E-2FA
 Probe Info  		H51(0.00); H42(0.00); H59(0.00); H110(0.00)  LDD2235  [11]
ATP probe
 Probe Info  		K21(0.00); K7(0.00); K30(0.00)  LDD0199  [12]
m-APA
 Probe Info  		H51(0.00); H42(0.00); H59(0.00); H110(0.00)  LDD2231  [11]
4-Iodoacetamidophenylacetylene
 Probe Info  		C84(0.00); C38(0.00)  LDD0038  [13]
IA-alkyne
 Probe Info  		C84(0.00); C38(0.00)  LDD0032  [14]
IPIAA_H
 Probe Info  		N.A.  LDD0030  [15]
IPIAA_L
 Probe Info  		C84(0.00); C38(0.00)  LDD0031  [15]
Lodoacetamide azide
 Probe Info  		C38(0.00); C84(0.00)  LDD0037  [13]
ATP probe
 Probe Info  		K7(0.00); K30(0.00)  LDD0035  [16]
IPM
 Probe Info  		N.A.  LDD0025  [17]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [17]
NAIA_4
 Probe Info  		N.A.  LDD2226  [18]
TFBX
 Probe Info  		N.A.  LDD0027  [17]
WYneN
 Probe Info  		N.A.  LDD0021  [19]
WYneO
 Probe Info  		N.A.  LDD0022  [19]
Compound 10
 Probe Info  		C38(0.00); C84(0.00)  LDD2216  [20]
Compound 11
 Probe Info  		N.A.  LDD2213  [20]
NHS
 Probe Info  		N.A.  LDD0010  [19]
NPM
 Probe Info  		N.A.  LDD0016  [19]
PF-06672131
 Probe Info  		N.A.  LDD0152  [21]
SF
 Probe Info  		N.A.  LDD0028  [22]
1c-yne
 Probe Info  		N.A.  LDD0228  [23]
1d-yne
 Probe Info  		N.A.  LDD0357  [23]
NAIA_5
 Probe Info  		C84(0.00); C38(0.00)  LDD2223  [18]
HHS-482
 Probe Info  		Y109(1.65)  LDD2239  [8]
PAL-AfBPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe3
 Probe Info  		6.50  LDD0464  [24]
STS-1
 Probe Info  		N.A.  LDD0136  [25]
Staurosporine capture compound
 Probe Info  		2.50  LDD0083  [26]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C84(0.41)  LDD2142  [4]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C84(0.78)  LDD2112  [4]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C84(0.36)  LDD2095  [4]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C84(1.01)  LDD2130  [4]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C84(0.89); C38(0.95)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C84(1.43)  LDD2152  [4]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C84(1.71)  LDD2103  [4]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C84(0.28)  LDD2132  [4]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C84(0.56)  LDD2131  [4]
 LDCM0214  AC1 HCT 116 C38(0.88)  LDD0531  [10]
 LDCM0215  AC10 HCT 116 C38(1.02)  LDD0532  [10]
 LDCM0216  AC100 HCT 116 C84(0.43)  LDD0533  [10]
 LDCM0217  AC101 HCT 116 C84(0.82)  LDD0534  [10]
 LDCM0218  AC102 HCT 116 C84(1.39)  LDD0535  [10]
 LDCM0219  AC103 HCT 116 C84(0.86)  LDD0536  [10]
 LDCM0220  AC104 HCT 116 C84(1.12)  LDD0537  [10]
 LDCM0221  AC105 HCT 116 C84(0.75)  LDD0538  [10]
 LDCM0222  AC106 HCT 116 C84(0.51)  LDD0539  [10]
 LDCM0223  AC107 HCT 116 C84(0.96)  LDD0540  [10]
 LDCM0224  AC108 HCT 116 C84(0.87)  LDD0541  [10]
 LDCM0225  AC109 HCT 116 C84(1.24)  LDD0542  [10]
 LDCM0226  AC11 HCT 116 C38(1.06)  LDD0543  [10]
 LDCM0227  AC110 HCT 116 C84(0.63)  LDD0544  [10]
 LDCM0228  AC111 HCT 116 C84(0.69)  LDD0545  [10]
 LDCM0229  AC112 HCT 116 C84(0.68)  LDD0546  [10]
 LDCM0237  AC12 HCT 116 C38(1.05)  LDD0554  [10]
 LDCM0246  AC128 HCT 116 C38(1.33); C84(0.97)  LDD0563  [10]
 LDCM0247  AC129 HCT 116 C38(1.24); C84(1.20)  LDD0564  [10]
 LDCM0249  AC130 HCT 116 C38(1.07); C84(1.39)  LDD0566  [10]
 LDCM0250  AC131 HCT 116 C38(1.18); C84(1.19)  LDD0567  [10]
 LDCM0251  AC132 HCT 116 C38(0.86); C84(1.51)  LDD0568  [10]
 LDCM0252  AC133 HCT 116 C38(1.12); C84(1.32)  LDD0569  [10]
 LDCM0253  AC134 HCT 116 C38(0.84); C84(1.39)  LDD0570  [10]
 LDCM0254  AC135 HCT 116 C38(0.82); C84(1.18)  LDD0571  [10]
 LDCM0255  AC136 HCT 116 C38(0.80); C84(1.24)  LDD0572  [10]
 LDCM0256  AC137 HCT 116 C38(0.90); C84(1.15)  LDD0573  [10]
 LDCM0257  AC138 HCT 116 C38(0.60); C84(1.30)  LDD0574  [10]
 LDCM0258  AC139 HCT 116 C38(0.66); C84(1.30)  LDD0575  [10]
 LDCM0259  AC14 HCT 116 C38(1.14)  LDD0576  [10]
 LDCM0260  AC140 HCT 116 C38(0.63); C84(1.37)  LDD0577  [10]
 LDCM0261  AC141 HCT 116 C38(0.64); C84(1.16)  LDD0578  [10]
 LDCM0262  AC142 HCT 116 C38(0.79); C84(1.12)  LDD0579  [10]
 LDCM0263  AC143 HCT 116 C38(0.94)  LDD0580  [10]
 LDCM0264  AC144 HCT 116 C38(0.70)  LDD0581  [10]
 LDCM0265  AC145 HCT 116 C38(0.90)  LDD0582  [10]
 LDCM0266  AC146 HCT 116 C38(0.85)  LDD0583  [10]
 LDCM0267  AC147 HCT 116 C38(0.74)  LDD0584  [10]
 LDCM0268  AC148 HCT 116 C38(0.48)  LDD0585  [10]
 LDCM0269  AC149 HCT 116 C38(0.67)  LDD0586  [10]
 LDCM0270  AC15 HCT 116 C38(1.16)  LDD0587  [10]
 LDCM0271  AC150 HCT 116 C38(0.95)  LDD0588  [10]
 LDCM0272  AC151 HCT 116 C38(0.87)  LDD0589  [10]
 LDCM0273  AC152 HCT 116 C38(0.71)  LDD0590  [10]
 LDCM0274  AC153 HCT 116 C38(0.40)  LDD0591  [10]
 LDCM0621  AC154 HCT 116 C38(0.80)  LDD2158  [10]
 LDCM0622  AC155 HCT 116 C38(0.88)  LDD2159  [10]
 LDCM0623  AC156 HCT 116 C38(1.08)  LDD2160  [10]
 LDCM0624  AC157 HCT 116 C38(0.89)  LDD2161  [10]
 LDCM0276  AC17 PaTu 8988t C38(0.82)  LDD1155  [10]
 LDCM0277  AC18 PaTu 8988t C38(0.58)  LDD1156  [10]
 LDCM0278  AC19 PaTu 8988t C38(0.78)  LDD1157  [10]
 LDCM0279  AC2 HCT 116 C38(0.87)  LDD0596  [10]
 LDCM0280  AC20 PaTu 8988t C38(0.59)  LDD1159  [10]
 LDCM0281  AC21 PaTu 8988t C38(0.53)  LDD1160  [10]
 LDCM0282  AC22 PaTu 8988t C38(0.46)  LDD1161  [10]
 LDCM0283  AC23 PaTu 8988t C38(0.54)  LDD1162  [10]
 LDCM0284  AC24 PaTu 8988t C38(0.43)  LDD1163  [10]
 LDCM0285  AC25 HCT 116 C38(1.24)  LDD0602  [10]
 LDCM0286  AC26 HCT 116 C38(0.68)  LDD0603  [10]
 LDCM0287  AC27 HCT 116 C38(0.88)  LDD0604  [10]
 LDCM0288  AC28 HCT 116 C38(0.64)  LDD0605  [10]
 LDCM0289  AC29 HCT 116 C38(0.49)  LDD0606  [10]
 LDCM0290  AC3 HCT 116 C38(0.76)  LDD0607  [10]
 LDCM0291  AC30 HCT 116 C38(0.50)  LDD0608  [10]
 LDCM0292  AC31 HCT 116 C38(0.56)  LDD0609  [10]
 LDCM0293  AC32 HCT 116 C38(0.42)  LDD0610  [10]
 LDCM0294  AC33 HCT 116 C38(1.04)  LDD0611  [10]
 LDCM0295  AC34 HCT 116 C38(1.10)  LDD0612  [10]
 LDCM0296  AC35 PaTu 8988t C38(1.04)  LDD1175  [10]
 LDCM0297  AC36 PaTu 8988t C38(0.61)  LDD1176  [10]
 LDCM0298  AC37 PaTu 8988t C38(0.79)  LDD1177  [10]
 LDCM0299  AC38 PaTu 8988t C38(0.88)  LDD1178  [10]
 LDCM0300  AC39 PaTu 8988t C38(0.70)  LDD1179  [10]
 LDCM0301  AC4 HCT 116 C38(0.77)  LDD0618  [10]
 LDCM0302  AC40 PaTu 8988t C38(0.68)  LDD1181  [10]
 LDCM0303  AC41 PaTu 8988t C38(0.93)  LDD1182  [10]
 LDCM0304  AC42 PaTu 8988t C38(1.01)  LDD1183  [10]
 LDCM0305  AC43 PaTu 8988t C38(0.97)  LDD1184  [10]
 LDCM0306  AC44 PaTu 8988t C38(0.83)  LDD1185  [10]
 LDCM0307  AC45 PaTu 8988t C38(1.01)  LDD1186  [10]
 LDCM0308  AC46 HCT 116 C84(1.17)  LDD0625  [10]
 LDCM0309  AC47 HCT 116 C84(1.16)  LDD0626  [10]
 LDCM0310  AC48 HCT 116 C84(1.11)  LDD0627  [10]
 LDCM0311  AC49 HCT 116 C84(0.62)  LDD0628  [10]
 LDCM0312  AC5 HCT 116 C38(0.70)  LDD0629  [10]
 LDCM0313  AC50 HCT 116 C84(0.79)  LDD0630  [10]
 LDCM0314  AC51 HCT 116 C84(1.31)  LDD0631  [10]
 LDCM0315  AC52 HCT 116 C84(1.19)  LDD0632  [10]
 LDCM0316  AC53 HCT 116 C84(0.84)  LDD0633  [10]
 LDCM0317  AC54 HCT 116 C84(0.92)  LDD0634  [10]
 LDCM0318  AC55 HCT 116 C84(0.63)  LDD0635  [10]
 LDCM0319  AC56 HCT 116 C84(0.22)  LDD0636  [10]
 LDCM0320  AC57 PaTu 8988t C38(0.89)  LDD1199  [10]
 LDCM0321  AC58 PaTu 8988t C38(0.80)  LDD1200  [10]
 LDCM0322  AC59 PaTu 8988t C38(0.84)  LDD1201  [10]
 LDCM0323  AC6 HCT 116 C38(0.97)  LDD0640  [10]
 LDCM0324  AC60 PaTu 8988t C38(0.56)  LDD1203  [10]
 LDCM0325  AC61 PaTu 8988t C38(0.82)  LDD1204  [10]
 LDCM0326  AC62 PaTu 8988t C38(0.82)  LDD1205  [10]
 LDCM0327  AC63 PaTu 8988t C38(0.79)  LDD1206  [10]
 LDCM0328  AC64 PaTu 8988t C38(0.90)  LDD1207  [10]
 LDCM0329  AC65 PaTu 8988t C38(0.85)  LDD1208  [10]
 LDCM0330  AC66 PaTu 8988t C38(0.59)  LDD1209  [10]
 LDCM0331  AC67 PaTu 8988t C38(0.80)  LDD1210  [10]
 LDCM0332  AC68 HCT 116 C84(0.85); C38(0.93)  LDD0649  [10]
 LDCM0333  AC69 HCT 116 C84(0.65); C38(0.87)  LDD0650  [10]
 LDCM0334  AC7 HCT 116 C38(1.00)  LDD0651  [10]
 LDCM0335  AC70 HCT 116 C84(0.47); C38(0.60)  LDD0652  [10]
 LDCM0336  AC71 HCT 116 C84(0.66); C38(0.96)  LDD0653  [10]
 LDCM0337  AC72 HCT 116 C84(0.77); C38(0.81)  LDD0654  [10]
 LDCM0338  AC73 HCT 116 C84(0.37); C38(0.51)  LDD0655  [10]
 LDCM0339  AC74 HCT 116 C84(0.37); C38(0.72)  LDD0656  [10]
 LDCM0340  AC75 HCT 116 C84(0.18); C38(0.40)  LDD0657  [10]
 LDCM0341  AC76 HCT 116 C84(0.66); C38(0.98)  LDD0658  [10]
 LDCM0342  AC77 HCT 116 C84(0.59); C38(0.73)  LDD0659  [10]
 LDCM0343  AC78 HCT 116 C84(0.61); C38(0.83)  LDD0660  [10]
 LDCM0344  AC79 HCT 116 C84(0.76); C38(0.78)  LDD0661  [10]
 LDCM0345  AC8 HCT 116 C38(0.96)  LDD0662  [10]
 LDCM0346  AC80 HCT 116 C84(0.75); C38(0.92)  LDD0663  [10]
 LDCM0347  AC81 HCT 116 C84(0.65); C38(0.78)  LDD0664  [10]
 LDCM0348  AC82 HCT 116 C84(0.13); C38(0.54)  LDD0665  [10]
 LDCM0349  AC83 HCT 116 C84(0.58)  LDD0666  [10]
 LDCM0350  AC84 HCT 116 C84(0.71)  LDD0667  [10]
 LDCM0351  AC85 HCT 116 C84(0.89)  LDD0668  [10]
 LDCM0352  AC86 HCT 116 C84(0.97)  LDD0669  [10]
 LDCM0353  AC87 HCT 116 C84(1.04)  LDD0670  [10]
 LDCM0354  AC88 HCT 116 C84(0.84)  LDD0671  [10]
 LDCM0355  AC89 HCT 116 C84(0.83)  LDD0672  [10]
 LDCM0357  AC90 HCT 116 C84(1.06)  LDD0674  [10]
 LDCM0358  AC91 HCT 116 C84(0.67)  LDD0675  [10]
 LDCM0359  AC92 HCT 116 C84(0.82)  LDD0676  [10]
 LDCM0360  AC93 HCT 116 C84(0.86)  LDD0677  [10]
 LDCM0361  AC94 HCT 116 C84(0.91)  LDD0678  [10]
 LDCM0362  AC95 HCT 116 C84(1.22)  LDD0679  [10]
 LDCM0363  AC96 HCT 116 C84(0.87)  LDD0680  [10]
 LDCM0364  AC97 HCT 116 C84(0.78)  LDD0681  [10]
 LDCM0365  AC98 HCT 116 C84(0.70)  LDD0682  [10]
 LDCM0366  AC99 HCT 116 C84(0.80)  LDD0683  [10]
 LDCM0545  Acetamide MDA-MB-231 C84(0.46)  LDD2138  [4]
 LDCM0520  AKOS000195272 MDA-MB-231 C84(0.73)  LDD2113  [4]
 LDCM0248  AKOS034007472 HCT 116 C38(1.16)  LDD0565  [10]
 LDCM0356  AKOS034007680 HCT 116 C38(1.21)  LDD0673  [10]
 LDCM0275  AKOS034007705 HCT 116 C38(0.69)  LDD0592  [10]
 LDCM0020  ARS-1620 HCC44 C84(0.97); C38(0.92)  LDD0078  [10]
 LDCM0498  BS-3668 MDA-MB-231 C84(0.60)  LDD2091  [4]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [9]
 LDCM0632  CL-Sc Hep-G2 C38(0.79)  LDD2227  [18]
 LDCM0367  CL1 HCT 116 C38(0.78)  LDD0684  [10]
 LDCM0368  CL10 HCT 116 C38(0.41)  LDD0685  [10]
 LDCM0369  CL100 HCT 116 C38(0.78)  LDD0686  [10]
 LDCM0370  CL101 HCT 116 C38(1.01)  LDD0687  [10]
 LDCM0371  CL102 HCT 116 C38(1.02)  LDD0688  [10]
 LDCM0372  CL103 HCT 116 C38(1.07)  LDD0689  [10]
 LDCM0373  CL104 HCT 116 C38(1.03)  LDD0690  [10]
 LDCM0374  CL105 PaTu 8988t C38(0.78)  LDD1253  [10]
 LDCM0375  CL106 PaTu 8988t C38(0.72)  LDD1254  [10]
 LDCM0376  CL107 PaTu 8988t C38(0.74)  LDD1255  [10]
 LDCM0377  CL108 PaTu 8988t C38(0.79)  LDD1256  [10]
 LDCM0378  CL109 PaTu 8988t C38(0.65)  LDD1257  [10]
 LDCM0379  CL11 HCT 116 C38(0.51)  LDD0696  [10]
 LDCM0380  CL110 PaTu 8988t C38(0.62)  LDD1259  [10]
 LDCM0381  CL111 PaTu 8988t C38(0.41)  LDD1260  [10]
 LDCM0382  CL112 HCT 116 C38(0.92)  LDD0699  [10]
 LDCM0383  CL113 HCT 116 C38(0.54)  LDD0700  [10]
 LDCM0384  CL114 HCT 116 C38(0.50)  LDD0701  [10]
 LDCM0385  CL115 HCT 116 C38(0.71)  LDD0702  [10]
 LDCM0386  CL116 HCT 116 C38(1.04)  LDD0703  [10]
 LDCM0387  CL117 PaTu 8988t C38(0.95)  LDD1266  [10]
 LDCM0388  CL118 PaTu 8988t C38(1.09)  LDD1267  [10]
 LDCM0389  CL119 PaTu 8988t C38(0.88)  LDD1268  [10]
 LDCM0390  CL12 HCT 116 C38(0.52)  LDD0707  [10]
 LDCM0391  CL120 PaTu 8988t C38(0.73)  LDD1270  [10]
 LDCM0392  CL121 HCT 116 C84(1.01)  LDD0709  [10]
 LDCM0393  CL122 HCT 116 C84(0.73)  LDD0710  [10]
 LDCM0394  CL123 HCT 116 C84(0.83)  LDD0711  [10]
 LDCM0395  CL124 HCT 116 C84(0.69)  LDD0712  [10]
 LDCM0396  CL125 PaTu 8988t C38(0.90)  LDD1275  [10]
 LDCM0397  CL126 PaTu 8988t C38(0.94)  LDD1276  [10]
 LDCM0398  CL127 PaTu 8988t C38(0.87)  LDD1277  [10]
 LDCM0399  CL128 PaTu 8988t C38(0.96)  LDD1278  [10]
 LDCM0400  CL13 HCT 116 C38(0.48)  LDD0717  [10]
 LDCM0401  CL14 HCT 116 C38(0.65)  LDD0718  [10]
 LDCM0402  CL15 HCT 116 C38(0.45)  LDD0719  [10]
 LDCM0403  CL16 HCT 116 C38(1.01)  LDD0720  [10]
 LDCM0404  CL17 HCT 116 C38(0.88)  LDD0721  [10]
 LDCM0405  CL18 HCT 116 C38(0.84)  LDD0722  [10]
 LDCM0406  CL19 HCT 116 C38(0.85)  LDD0723  [10]
 LDCM0407  CL2 HCT 116 C38(0.76)  LDD0724  [10]
 LDCM0408  CL20 HCT 116 C38(0.82)  LDD0725  [10]
 LDCM0409  CL21 HCT 116 C38(0.57)  LDD0726  [10]
 LDCM0410  CL22 HCT 116 C38(0.27)  LDD0727  [10]
 LDCM0411  CL23 HCT 116 C38(1.12)  LDD0728  [10]
 LDCM0412  CL24 HCT 116 C38(0.80)  LDD0729  [10]
 LDCM0413  CL25 HCT 116 C38(0.75)  LDD0730  [10]
 LDCM0414  CL26 HCT 116 C38(0.93)  LDD0731  [10]
 LDCM0415  CL27 HCT 116 C38(0.87)  LDD0732  [10]
 LDCM0416  CL28 HCT 116 C38(0.78)  LDD0733  [10]
 LDCM0417  CL29 HCT 116 C38(0.70)  LDD0734  [10]
 LDCM0418  CL3 HCT 116 C38(0.77)  LDD0735  [10]
 LDCM0419  CL30 HCT 116 C38(0.84)  LDD0736  [10]
 LDCM0420  CL31 HCT 116 C38(0.83)  LDD0737  [10]
 LDCM0421  CL32 HCT 116 C38(0.68)  LDD0738  [10]
 LDCM0422  CL33 HCT 116 C38(0.68)  LDD0739  [10]
 LDCM0423  CL34 HCT 116 C38(0.43)  LDD0740  [10]
 LDCM0424  CL35 HCT 116 C38(0.52)  LDD0741  [10]
 LDCM0425  CL36 HCT 116 C38(0.61)  LDD0742  [10]
 LDCM0426  CL37 HCT 116 C38(0.47)  LDD0743  [10]
 LDCM0428  CL39 HCT 116 C38(0.53)  LDD0745  [10]
 LDCM0429  CL4 HCT 116 C38(0.71)  LDD0746  [10]
 LDCM0430  CL40 HCT 116 C38(0.63)  LDD0747  [10]
 LDCM0431  CL41 HCT 116 C38(0.66)  LDD0748  [10]
 LDCM0432  CL42 HCT 116 C38(0.18)  LDD0749  [10]
 LDCM0433  CL43 HCT 116 C38(0.44)  LDD0750  [10]
 LDCM0434  CL44 HCT 116 C38(0.53)  LDD0751  [10]
 LDCM0435  CL45 HCT 116 C38(0.35)  LDD0752  [10]
 LDCM0436  CL46 HEK-293T C38(1.03)  LDD1640  [27]
 LDCM0437  CL47 HEK-293T C84(1.14); C38(1.06)  LDD1641  [27]
 LDCM0438  CL48 HEK-293T C84(1.07); C38(1.04)  LDD1642  [27]
 LDCM0439  CL49 HEK-293T C84(0.95); C38(1.00)  LDD1643  [27]
 LDCM0440  CL5 HCT 116 C38(0.72)  LDD0757  [10]
 LDCM0441  CL50 HEK-293T C84(0.98); C38(0.98)  LDD1645  [27]
 LDCM0443  CL52 HEK-293T C84(0.90); C38(1.05)  LDD1646  [27]
 LDCM0444  CL53 HEK-293T C84(0.97); C38(0.93)  LDD1647  [27]
 LDCM0445  CL54 HEK-293T C84(0.93); C38(0.89)  LDD1648  [27]
 LDCM0446  CL55 HEK-293T C84(1.05); C38(0.97)  LDD1649  [27]
 LDCM0447  CL56 HEK-293T C84(1.04); C38(0.99)  LDD1650  [27]
 LDCM0448  CL57 HEK-293T C84(1.00); C38(0.97)  LDD1651  [27]
 LDCM0449  CL58 HEK-293T C38(0.97)  LDD1652  [27]
 LDCM0450  CL59 HEK-293T C84(1.17); C38(1.07)  LDD1653  [27]
 LDCM0451  CL6 HCT 116 C38(0.57)  LDD0768  [10]
 LDCM0452  CL60 HEK-293T C84(1.00); C38(0.94)  LDD1655  [27]
 LDCM0453  CL61 HCT 116 C38(0.86)  LDD0770  [10]
 LDCM0454  CL62 HCT 116 C38(0.76)  LDD0771  [10]
 LDCM0455  CL63 HCT 116 C38(0.66)  LDD0772  [10]
 LDCM0456  CL64 HCT 116 C38(0.63)  LDD0773  [10]
 LDCM0457  CL65 HCT 116 C38(0.68)  LDD0774  [10]
 LDCM0458  CL66 HCT 116 C38(0.53)  LDD0775  [10]
 LDCM0459  CL67 HCT 116 C38(0.68)  LDD0776  [10]
 LDCM0460  CL68 HCT 116 C38(0.75)  LDD0777  [10]
 LDCM0461  CL69 HCT 116 C38(0.88)  LDD0778  [10]
 LDCM0462  CL7 HCT 116 C38(0.53)  LDD0779  [10]
 LDCM0463  CL70 HCT 116 C38(0.75)  LDD0780  [10]
 LDCM0464  CL71 HCT 116 C38(0.72)  LDD0781  [10]
 LDCM0465  CL72 HCT 116 C38(0.83)  LDD0782  [10]
 LDCM0466  CL73 HCT 116 C38(0.75)  LDD0783  [10]
 LDCM0467  CL74 HCT 116 C38(0.81)  LDD0784  [10]
 LDCM0469  CL76 HCT 116 C38(0.75)  LDD0786  [10]
 LDCM0470  CL77 HCT 116 C38(0.82)  LDD0787  [10]
 LDCM0471  CL78 HCT 116 C38(0.77)  LDD0788  [10]
 LDCM0472  CL79 HCT 116 C38(0.69)  LDD0789  [10]
 LDCM0473  CL8 HCT 116 C38(0.48)  LDD0790  [10]
 LDCM0474  CL80 HCT 116 C38(0.89)  LDD0791  [10]
 LDCM0475  CL81 HCT 116 C38(0.83)  LDD0792  [10]
 LDCM0476  CL82 HCT 116 C38(0.55)  LDD0793  [10]
 LDCM0477  CL83 HCT 116 C38(0.61)  LDD0794  [10]
 LDCM0478  CL84 HCT 116 C38(0.30)  LDD0795  [10]
 LDCM0479  CL85 HCT 116 C38(0.78)  LDD0796  [10]
 LDCM0480  CL86 HCT 116 C38(0.95)  LDD0797  [10]
 LDCM0481  CL87 HCT 116 C38(0.74)  LDD0798  [10]
 LDCM0482  CL88 HCT 116 C38(0.61)  LDD0799  [10]
 LDCM0483  CL89 HCT 116 C38(0.19)  LDD0800  [10]
 LDCM0484  CL9 HCT 116 C38(0.70)  LDD0801  [10]
 LDCM0485  CL90 HCT 116 C38(0.76)  LDD0802  [10]
 LDCM0486  CL91 HCT 116 C38(0.89)  LDD0803  [10]
 LDCM0487  CL92 HCT 116 C38(0.70)  LDD0804  [10]
 LDCM0488  CL93 HCT 116 C38(0.85)  LDD0805  [10]
 LDCM0489  CL94 HCT 116 C38(0.73)  LDD0806  [10]
 LDCM0490  CL95 HCT 116 C38(0.65)  LDD0807  [10]
 LDCM0491  CL96 HCT 116 C38(0.78)  LDD0808  [10]
 LDCM0492  CL97 HCT 116 C38(0.76)  LDD0809  [10]
 LDCM0493  CL98 HCT 116 C38(0.78)  LDD0810  [10]
 LDCM0494  CL99 HCT 116 C38(0.84)  LDD0811  [10]
 LDCM0191  Compound 21 HEK-293T 3.35  LDD0508  [24]
 LDCM0190  Compound 34 HEK-293T 3.25  LDD0510  [24]
 LDCM0193  Compound 36 HEK-293T 3.13  LDD0511  [24]
 LDCM0495  E2913 HEK-293T C84(1.09); C38(0.98)  LDD1698  [27]
 LDCM0625  F8 Ramos C84(0.66); C38(1.44)  LDD2187  [28]
 LDCM0572  Fragment10 MDA-MB-231 C84(0.89)  LDD1389  [29]
 LDCM0573  Fragment11 MDA-MB-231 C84(0.76)  LDD1391  [29]
 LDCM0574  Fragment12 MDA-MB-231 C84(0.86)  LDD1393  [29]
 LDCM0575  Fragment13 MDA-MB-231 C84(0.87)  LDD1395  [29]
 LDCM0576  Fragment14 MDA-MB-231 C84(0.89)  LDD1397  [29]
 LDCM0577  Fragment15 Ramos C84(0.80)  LDD1400  [29]
 LDCM0579  Fragment20 MDA-MB-231 C84(0.55)  LDD1402  [29]
 LDCM0580  Fragment21 MDA-MB-231 C84(0.68)  LDD1404  [29]
 LDCM0582  Fragment23 Ramos C84(1.09)  LDD1409  [29]
 LDCM0583  Fragment24 Ramos C84(1.11)  LDD1410  [29]
 LDCM0578  Fragment27 MDA-MB-231 C84(1.03)  LDD1401  [29]
 LDCM0586  Fragment28 Ramos C84(0.50); C38(0.83)  LDD2198  [28]
 LDCM0587  Fragment29 MDA-MB-231 C84(0.59)  LDD1417  [29]
 LDCM0588  Fragment30 Ramos C84(1.22); C38(0.30)  LDD2199  [28]
 LDCM0589  Fragment31 Ramos C84(0.80)  LDD1422  [29]
 LDCM0590  Fragment32 MDA-MB-231 C84(0.73)  LDD1423  [29]
 LDCM0468  Fragment33 HCT 116 C38(0.70)  LDD0785  [10]
 LDCM0596  Fragment38 Ramos C84(1.55); C38(1.43)  LDD2203  [28]
 LDCM0566  Fragment4 MDA-MB-231 C84(0.64)  LDD1378  [29]
 LDCM0598  Fragment40 MDA-MB-231 C84(0.76)  LDD1436  [29]
 LDCM0603  Fragment45 MDA-MB-231 C84(0.85)  LDD1444  [29]
 LDCM0604  Fragment46 MDA-MB-231 C84(0.80)  LDD1445  [29]
 LDCM0605  Fragment47 MDA-MB-231 C84(0.87)  LDD1446  [29]
 LDCM0607  Fragment49 MDA-MB-231 C84(0.81)  LDD1448  [29]
 LDCM0427  Fragment51 HCT 116 C38(0.29)  LDD0744  [10]
 LDCM0610  Fragment52 Ramos C84(1.13); C38(0.57)  LDD2204  [28]
 LDCM0611  Fragment53 MDA-MB-231 C84(0.56)  LDD1454  [29]
 LDCM0614  Fragment56 MDA-MB-231 C84(0.58)  LDD1458  [29]
 LDCM0569  Fragment7 Ramos C84(0.54); C38(0.56)  LDD2186  [28]
 LDCM0570  Fragment8 MDA-MB-231 C84(20.00)  LDD1385  [29]
 LDCM0571  Fragment9 MDA-MB-231 C84(0.86)  LDD1387  [29]
 LDCM0116  HHS-0101 DM93 Y109(0.83)  LDD0264  [7]
 LDCM0117  HHS-0201 DM93 Y109(0.79)  LDD0265  [7]
 LDCM0118  HHS-0301 DM93 Y109(1.02)  LDD0266  [7]
 LDCM0119  HHS-0401 DM93 Y109(0.78)  LDD0267  [7]
 LDCM0120  HHS-0701 DM93 Y109(0.84)  LDD0268  [7]
 LDCM0022  KB02 HCT 116 C84(1.33)  LDD0080  [10]
 LDCM0023  KB03 HCT 116 C84(1.41)  LDD0081  [10]
 LDCM0024  KB05 HCT 116 C84(1.45)  LDD0082  [10]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C84(1.22)  LDD2102  [4]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C84(0.71)  LDD2121  [4]
 LDCM0109  NEM HeLa N.A.  LDD0230  [9]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C84(0.66)  LDD2089  [4]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C84(0.99)  LDD2090  [4]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C84(1.43)  LDD2092  [4]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C84(1.65)  LDD2093  [4]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C84(2.89)  LDD2094  [4]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C84(0.24)  LDD2096  [4]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C84(0.90)  LDD2097  [4]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C84(1.26)  LDD2098  [4]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C84(1.31)  LDD2099  [4]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C84(0.52)  LDD2100  [4]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C84(1.07)  LDD2101  [4]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C84(0.51)  LDD2104  [4]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C84(1.90)  LDD2105  [4]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C84(0.35)  LDD2106  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C84(0.82)  LDD2107  [4]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C84(0.48)  LDD2108  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C84(0.69)  LDD2109  [4]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C84(0.66)  LDD2110  [4]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C84(0.97)  LDD2111  [4]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C84(0.49)  LDD2114  [4]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C84(0.40)  LDD2115  [4]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C84(0.53)  LDD2116  [4]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C84(0.57)  LDD2118  [4]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C84(0.69)  LDD2119  [4]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C84(0.77)  LDD2120  [4]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C84(0.41)  LDD2122  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C84(0.74); C38(0.87)  LDD2123  [4]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C84(0.38)  LDD2124  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C84(0.90)  LDD2125  [4]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C84(0.39)  LDD2126  [4]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C84(1.08)  LDD2127  [4]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C84(0.74)  LDD2128  [4]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C84(1.38)  LDD2129  [4]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C84(0.55)  LDD2133  [4]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C84(0.51)  LDD2134  [4]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C84(1.39)  LDD2135  [4]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C84(1.16)  LDD2136  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C84(1.02)  LDD2137  [4]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C84(2.92)  LDD1700  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C84(0.87)  LDD2140  [4]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C84(0.44)  LDD2141  [4]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C84(0.74)  LDD2143  [4]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C84(3.08)  LDD2144  [4]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C84(4.74)  LDD2145  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C84(0.98)  LDD2146  [4]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C84(2.25)  LDD2147  [4]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C84(0.45)  LDD2148  [4]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C84(0.50)  LDD2149  [4]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C84(0.54)  LDD2150  [4]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C84(0.39)  LDD2151  [4]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C84(1.08)  LDD2153  [4]
 LDCM0131  RA190 MM1.R C84(1.34)  LDD0304  [30]
 LDCM0019  Staurosporine Hep-G2 2.50  LDD0083  [26]
 LDCM0021  THZ1 HCT 116 C84(1.07); C38(1.03)  LDD2173  [10]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Approved
Click To Hide/Show 2 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Adenosine Phosphate Small molecular drug DB00131
Sofosbuvir Small molecular drug DB08934
Investigative
Click To Hide/Show 4 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
8-bromo-adenosine-5'-monophosphate Small molecular drug DB03349
Guanosine-5'-monophosphate Small molecular drug DB01972
5'-o-(N-ethyl-sulfamoyl)Adenosine . DB02162
Adenosine-5'-ditungstate . DB02183

References

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2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.
6 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
7 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
8 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
9 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
10 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
11 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
12 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
13 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
14 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
15 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
16 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
17 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
18 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
19 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
20 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
21 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
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Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD044402
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