Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0551
Competitor Name
Nucleophilic fragment 5b
Synonyms
N-(2-methyl-5-(trifluoromethyl)phenyl)-2-nitroacetamide
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 262.18
Lipid-water partition coefficient (xlogp) 2.5
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C10H9F3N2O3
IUPAC Name
N-[2-methyl-5-(trifluoromethyl)phenyl]-2-nitroacetamide
Canonical SMILES
CC1=C(C=C(C=C1)C(F)(F)F)NC(=O)C[N+](=O)[O-]
InChI
InChI=1S/C10H9F3N2O3/c1-6-2-3-7(10(11,12)13)4-8(6)14-9(16)5-15(17)18/h2-4H,5H2,1H3,(H,14,16)
InChIKey
BYUSZQLRRSSBKE-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
BTD
 Probe Info  		5 mM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

335 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) LDTP06286 0.37; 0.77  LDD2145 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 0.24  LDD2145 
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 1.34  LDD2145 
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) LDTP01268 0.28  LDD2145 
2-hydroxyacyl-CoA lyase 1 (HACL1) LDTP13375 0.63  LDD2145 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 0.81; 0.43  LDD2145 
2-oxoglutarate dehydrogenase complex component E1 (OGDH) LDTP05341 0.29  LDD2145 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 1.74  LDD2145 
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 7.38; 2.00  LDD2145 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 2.61  LDD2145 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 3.26; 0.25  LDD2145 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 0.39  LDD2145 
26S proteasome regulatory subunit 6A (PSMC3) LDTP02933 0.35; 2.29; 1.49  LDD2145 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.68  LDD2145 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 0.23  LDD2145 
3'(2'),5'-bisphosphate nucleotidase 1 (BPNT1) LDTP01697 0.51  LDD2145 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.24  LDD2145 
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) LDTP07483 1.57  LDD2145 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 0.67  LDD2145 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 3.10; 0.12  LDD2145 
5'-nucleotidase (NT5E) LDTP03120 0.29  LDD2145 
5-hydroxymethyl-dUMP N-hydrolase (DNPH1) LDTP00813 0.40  LDD2145 
6-phosphogluconolactonase (PGLS) LDTP14535 0.63  LDD2145 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.82  LDD2145 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 0.21  LDD2145 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.83; 6.61; 5.94  LDD2145 
Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) LDTP16274 2.42  LDD2145 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 4.74  LDD2145 
Adenosine kinase (ADK) LDTP04689 0.40  LDD2145 
Adenosylhomocysteinase (AHCY) LDTP03242 0.31; 0.76  LDD2145 
Adenylate kinase 2, mitochondrial (AK2) LDTP04636 1.90  LDD2145 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 0.15  LDD2145 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.73  LDD2145 
Aldehyde dehydrogenase 1A1 (ALDH1A1) LDTP01767 0.92; 0.70  LDD2145 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 0.34  LDD2145 
Aldehyde dehydrogenase, mitochondrial (ALDH2) LDTP02074 0.47  LDD2145 
Aldehyde oxidase (AOX1) LDTP05483 0.18  LDD2145 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 11.87; 0.36; 0.31  LDD2145 
Aldo-keto reductase family 1 member B15 (AKR1B15) LDTP00174 0.69  LDD2145 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 1.02  LDD2145 
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) LDTP04253 2.94  LDD2145 
Alpha-enolase (ENO1) LDTP02159 0.29; 0.30; 0.14  LDD2145 
Aminoacylase-1 (ACY1) LDTP05395 0.19  LDD2145 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 0.19  LDD2145 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 1.08  LDD2145 
ATP synthase subunit epsilon-like protein, mitochondrial (ATP5F1EP2) LDTP17268 0.25  LDD2145 
ATP-binding cassette sub-family C member 5 (ABCC5) LDTP00640 0.09  LDD2145 
ATP-citrate synthase (ACLY) LDTP04561 15.05  LDD2145 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.38; 0.66; 0.48 ...  LDD2145 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 0.38  LDD2145 
ATP-dependent RNA helicase DDX18 (DDX18) LDTP12688 2.82  LDD2145 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 13.81  LDD2145 
ATP-dependent RNA helicase DDX3Y (DDX3Y) LDTP00664 5.13  LDD2145 
ATP-dependent RNA helicase DDX42 (DDX42) LDTP08369 0.22  LDD2145 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 0.59  LDD2145 
ATP-dependent RNA helicase DHX30 (DHX30) LDTP07946 13.83; 1.60  LDD2145 
Aurora kinase A (AURKA) LDTP00491 0.85  LDD2145 
Betaine--homocysteine S-methyltransferase 1 (BHMT) LDTP09978 1.83  LDD2145 
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2) LDTP01564 0.87  LDD2145 
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (JMJD6) LDTP07492 0.20  LDD2145 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.18; 0.93  LDD2145 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 0.28  LDD2145 
Bleomycin hydrolase (BLMH) LDTP05992 0.20  LDD2145 
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) LDTP04622 0.32  LDD2145 
Calcyclin-binding protein (CACYBP) LDTP12163 0.28  LDD2145 
Carboxypeptidase D (CPD) LDTP01372 2.16  LDD2145 
Casein kinase II subunit alpha 3 (CSNK2A3) LDTP09176 0.99  LDD2145 
Catalase (CAT) LDTP02001 0.21  LDD2145 
Chromodomain-helicase-DNA-binding protein 8 (CHD8) LDTP12252 4.11  LDD2145 
Citrate synthase, mitochondrial (CS) LDTP01205 1.01  LDD2145 
Cleavage and polyadenylation specificity factor subunit 3 (CPSF3) LDTP13449 1.20  LDD2145 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 0.26  LDD2145 
CTD nuclear envelope phosphatase 1 (CTDNEP1) LDTP01616 5.47  LDD2145 
CTP synthase 1 (CTPS1) LDTP02922 4.80; 2.92  LDD2145 
Cullin-1 (CUL1) LDTP05946 0.96  LDD2145 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 4.18  LDD2145 
Cyclin-dependent kinase 7 (CDK7) LDTP04379 1.21  LDD2145 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 3.44  LDD2145 
Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) LDTP02229 2.25; 1.18; 5.47 ...  LDD2145 
Cytochrome c1, heme protein, mitochondrial (CYC1) LDTP02283 1.00  LDD2145 
Cytokine-like nuclear factor N-PAC (GLYR1) LDTP06828 1.22  LDD2145 
Cytosolic 10-formyltetrahydrofolate dehydrogenase (ALDH1L1) LDTP01341 0.62; 0.97  LDD2145 
Cytosolic beta-glucosidase (GBA3) LDTP11789 0.20  LDD2145 
DDB1- and CUL4-associated factor 1 (DCAF1) LDTP14038 1.17  LDD2145 
Delta(24)-sterol reductase (DHCR24) LDTP06375 4.42  LDD2145 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 0.05; 0.28  LDD2145 
Deoxyribose-phosphate aldolase (DERA) LDTP13941 0.92; 0.36  LDD2145 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) LDTP03669 0.53  LDD2145 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 0.14; 0.82  LDD2145 
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) LDTP02497 0.19  LDD2145 
Dipeptidyl peptidase 9 (DPP9) LDTP08198 1.66  LDD2145 
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) LDTP00403 0.13  LDD2145 
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) LDTP05137 0.22  LDD2145 
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM33) LDTP11512 1.93  LDD2145 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 6.60  LDD2145 
DNA ligase 1 (LIG1) LDTP02971 10.47  LDD2145 
DNA repair protein RAD50 (RAD50) LDTP09912 0.61; 0.20  LDD2145 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 4.22  LDD2145 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 1.62  LDD2145 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 4.94  LDD2145 
DNA topoisomerase 1 (TOP1) LDTP02567 1.15  LDD2145 
DNA topoisomerase 2-alpha (TOP2A) LDTP02568 2.07; 0.20  LDD2145 
DNA topoisomerase 2-beta (TOP2B) LDTP05379 0.50  LDD2145 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 13.01; 11.28; 6.78 ...  LDD2145 
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (POLR2H) LDTP04507 0.49  LDD2145 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 3.16  LDD2145 
Double-strand break repair protein MRE11 (MRE11) LDTP04337 0.16  LDD2145 
Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 0.43; 0.39  LDD2145 
E3 SUMO-protein ligase NSE2 (NSMCE2) LDTP10583 2.61  LDD2145 
E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 0.94; 2.31; 1.55  LDD2145 
E3 ubiquitin-protein ligase Itchy homolog (ITCH) LDTP10441 4.27  LDD2145 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 5.54  LDD2145 
Elongation factor 2 (EEF2) LDTP02672 1.30; 0.13; 0.15 ...  LDD2145 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 5.65  LDD2145 
Enoyl-CoA delta isomerase 2 (ECI2) LDTP01245 0.15  LDD2145 
ERO1-like protein alpha (ERO1A) LDTP10386 3.85; 0.70  LDD2145 
Estradiol 17-beta-dehydrogenase 11 (HSD17B11) LDTP09063 0.54  LDD2145 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 0.66  LDD2145 
Eukaryotic translation initiation factor 2 subunit 3B (EIF2S3B) LDTP14895 0.41  LDD2145 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 5.96  LDD2145 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 4.09  LDD2145 
Exosome complex component 10 (EXOSC10) LDTP05312 7.72  LDD2145 
Exosome complex component MTR3 (EXOSC6) LDTP07054 0.43; 5.89; 0.60 ...  LDD2145 
Exosome complex component RRP42 (EXOSC7) LDTP06283 0.56  LDD2145 
Exosome complex component RRP43 (EXOSC8) LDTP10110 0.47; 4.43  LDD2145 
Exosome complex component RRP46 (EXOSC5) LDTP12433 0.93  LDD2145 
Exosome RNA helicase MTR4 (MTREX) LDTP03975 0.98  LDD2145 
FACT complex subunit SPT16 (SUPT16H) LDTP14109 0.09  LDD2145 
Fatty acid synthase (FASN) LDTP04243 1.50; 1.77  LDD2145 
Fumarylacetoacetase (FAH) LDTP02868 0.19  LDD2145 
Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1) LDTP10264 1.37  LDD2145 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 0.40  LDD2145 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.27  LDD2145 
Glutamate dehydrogenase 1, mitochondrial (GLUD1) LDTP01768 0.13  LDD2145 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 2.44  LDD2145 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 6.95; 13.95  LDD2145 
Glutathione synthetase (GSS) LDTP04200 0.15  LDD2145 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 1.56; 5.88  LDD2145 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 0.22; 0.85  LDD2145 
Glycine--tRNA ligase (GARS1) LDTP03946 15.41  LDD2145 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.50  LDD2145 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 5.98  LDD2145 
GPI-anchor transamidase (PIGK) LDTP09835 2.26  LDD2145 
GTP-binding nuclear protein Ran (RAN) LDTP05007 1.92  LDD2145 
GTP-binding protein 4 (GTPBP4) LDTP11529 1.48; 1.50  LDD2145 
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1) LDTP01061 0.35  LDD2145 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 1.23; 0.07; 0.04  LDD2145 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.16  LDD2145 
Heme oxygenase 2 (HMOX2) LDTP03540 6.92; 4.08  LDD2145 
Hepatocyte growth factor (HGF) LDTP02716 3.83  LDD2145 
Hexokinase-1 (HK1) LDTP02991 6.78  LDD2145 
Hexokinase-2 (HK2) LDTP04531 2.19  LDD2145 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 2.91; 1.04  LDD2145 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 1.54  LDD2145 
Histone deacetylase 2 (HDAC2) LDTP09865 1.67  LDD2145 
Histone-lysine N-methyltransferase SETD7 (SETD7) LDTP09543 1.26  LDD2145 
Hydroxyacid-oxoacid transhydrogenase, mitochondrial (ADHFE1) LDTP08567 0.37  LDD2145 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.56  LDD2145 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 1.97  LDD2145 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 6.46  LDD2145 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.17  LDD2145 
Inositol monophosphatase 1 (IMPA1) LDTP03470 0.23  LDD2145 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 0.48  LDD2145 
Ketohexokinase (KHK) LDTP04340 0.22  LDD2145 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.25  LDD2145 
Lanosterol synthase (LSS) LDTP04183 0.18  LDD2145 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 5.87  LDD2145 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 0.71  LDD2145 
Long-chain-fatty-acid--CoA ligase 5 (ACSL5) LDTP13533 1.03  LDD2145 
Lysine-specific demethylase 3B (KDM3B) LDTP07982 2.84  LDD2145 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.38; 0.30  LDD2145 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.12; 0.19; 0.13  LDD2145 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.13; 0.21; 0.08 ...  LDD2145 
Methionine aminopeptidase 2 (METAP2) LDTP04375 0.35  LDD2145 
Methylmalonyl-CoA mutase, mitochondrial (MMUT) LDTP03150 0.37  LDD2145 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 6.18  LDD2145 
Mitochondrial genome maintenance exonuclease 1 (MGME1) LDTP11090 2.51  LDD2145 
Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 2.71  LDD2145 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 3.28  LDD2145 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 1.84  LDD2145 
mRNA cap guanine-N7 methyltransferase (RNMT) LDTP00686 2.82; 2.51  LDD2145 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 3.43  LDD2145 
Multifunctional protein CAD (CAD) LDTP03401 2.32  LDD2145 
MYG1 exonuclease (MYG1) LDTP12154 0.28  LDD2145 
Myosin-10 (MYH10) LDTP03765 3.12  LDD2145 
Myosin-9 (MYH9) LDTP03764 0.39; 7.10; 7.39  LDD2145 
N-acetyl-D-glucosamine kinase (NAGK) LDTP13372 3.44  LDD2145 
N-acylneuraminate cytidylyltransferase (CMAS) LDTP09228 9.59  LDD2145 
N-alpha-acetyltransferase 25, NatB auxiliary subunit (NAA25) LDTP06262 2.87  LDD2145 
NAD kinase 2, mitochondrial (NADK2) LDTP06839 4.18  LDD2145 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 1.24  LDD2145 
NADH dehydrogenase flavoprotein 1, mitochondrial (NDUFV1) LDTP04317 0.67  LDD2145 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 5.36  LDD2145 
NADH dehydrogenase iron-sulfur protein 6, mitochondrial (NDUFS6) LDTP14493 0.68  LDD2145 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 2.59  LDD2145 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 1.87  LDD2145 
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT) LDTP06346 0.29  LDD2145 
Nuclear pore complex protein Nup98-Nup96 (NUP98) LDTP04547 0.17  LDD2145 
Nucleolar GTP-binding protein 2 (GNL2) LDTP05987 3.29  LDD2145 
Nucleolar RNA helicase 2 (DDX21) LDTP12469 3.40; 0.90  LDD2145 
Nucleoside diphosphate kinase B (NME2) LDTP03169 0.51  LDD2145 
Omega-amidase NIT2 (NIT2) LDTP12428 0.60  LDD2145 
Ornithine aminotransferase, mitochondrial (OAT) LDTP02021 0.72  LDD2145 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 0.05; 0.11  LDD2145 
Parkinson disease protein 7 (PARK7) LDTP10878 0.43; 0.69  LDD2145 
Patatin-like phospholipase domain-containing protein 6 (PNPLA6) LDTP08617 1.50  LDD2145 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 0.24; 0.30; 1.22  LDD2145 
Peptidyl-prolyl cis-trans isomerase B (PPIB) LDTP03216 0.12  LDD2145 
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF) LDTP03534 0.66  LDD2145 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.20  LDD2145 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.15; 0.17  LDD2145 
Peptidyl-prolyl cis-trans isomerase G (PPIG) LDTP05866 0.70  LDD2145 
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1) LDTP13976 0.60  LDD2145 
Peptidyl-prolyl cis-trans isomerase-like 4 (PPIL4) LDTP15620 0.17  LDD2145 
Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) LDTP13989 0.32  LDD2145 
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (PPWD1) LDTP10135 0.12  LDD2145 
Peroxiredoxin-6 (PRDX6) LDTP03510 1.27  LDD2145 
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (DECR2) LDTP12627 0.25  LDD2145 
Peroxisomal acyl-coenzyme A oxidase 2 (ACOX2) LDTP10859 0.46  LDD2145 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 0.08; 1.13  LDD2145 
Persulfide dioxygenase ETHE1, mitochondrial (ETHE1) LDTP01633 0.30  LDD2145 
Phosphoacetylglucosamine mutase (PGM3) LDTP01584 0.35; 0.38  LDD2145 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 1.21  LDD2145 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 0.48  LDD2145 
Phospholipid scramblase 1 (PLSCR1) LDTP00558 1.37  LDD2145 
Phosphopentomutase (PGM2) LDTP10326 1.71; 0.34; 0.39  LDD2145 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 8.08  LDD2145 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 0.22; 0.53; 7.25  LDD2145 
Pre-mRNA-processing factor 19 (PRPF19) LDTP13623 0.84  LDD2145 
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (DHX16) LDTP00915 1.54  LDD2145 
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (FTSJ3) LDTP08629 0.62  LDD2145 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 0.18  LDD2145 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 0.66  LDD2145 
Presequence protease, mitochondrial (PITRM1) LDTP07003 0.17  LDD2145 
Probable ATP-dependent RNA helicase DDX47 (DDX47) LDTP11730 0.30  LDD2145 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 7.30; 1.26  LDD2145 
Probable ATP-dependent RNA helicase DDX6 (DDX6) LDTP03348 0.33  LDD2145 
Probable ATP-dependent RNA helicase DHX37 (DHX37) LDTP08625 0.95  LDD2145 
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG8) LDTP11290 4.83  LDD2145 
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 2.02  LDD2145 
Procollagen galactosyltransferase 1 (COLGALT1) LDTP09055 0.94  LDD2145 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) LDTP05373 0.18  LDD2145 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 0.56  LDD2145 
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) LDTP02095 0.24; 1.25  LDD2145 
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) LDTP02096 1.00; 1.83  LDD2145 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.23; 0.17; 0.23  LDD2145 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 0.16  LDD2145 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 0.18  LDD2145 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 0.11; 0.14  LDD2145 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.12  LDD2145 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 0.17; 0.26  LDD2145 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.05; 0.79  LDD2145 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 0.16  LDD2145 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 0.19  LDD2145 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 7.46  LDD2145 
Protein disulfide-isomerase (P4HB) LDTP02188 0.57; 0.13  LDD2145 
Protein phosphatase 1G (PPM1G) LDTP00616 4.03  LDD2145 
Protein PML (PML) LDTP03496 0.64  LDD2145 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 6.78  LDD2145 
Purine nucleoside phosphorylase (PNP) LDTP01781 0.27  LDD2145 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 10.24  LDD2145 
Pyruvate carboxylase, mitochondrial (PC) LDTP02576 1.73  LDD2145 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 1.05; 1.01  LDD2145 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 0.96  LDD2145 
Pyruvate dehydrogenase protein X component, mitochondrial (PDHX) LDTP00253 0.21  LDD2145 
Pyruvate kinase PKM (PKM) LDTP02733 4.41; 3.05  LDD2145 
Quinone oxidoreductase (CRYZ) LDTP05551 0.43  LDD2145 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.41  LDD2145 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 4.79; 4.81  LDD2145 
Ras-related protein Rab-10 (RAB10) LDTP04895 2.19  LDD2145 
Ras-related protein Rab-14 (RAB14) LDTP04901 3.13  LDD2145 
Ribokinase (RBKS) LDTP11903 0.69  LDD2145 
Ribonucleases P/MRP protein subunit POP1 (POP1) LDTP10903 2.94  LDD2145 
Ribose-5-phosphate isomerase (RPIA) LDTP04236 0.15  LDD2145 
Ribosome biogenesis protein BMS1 homolog (BMS1) LDTP06188 3.23  LDD2145 
RNA cytidine acetyltransferase (NAT10) LDTP11690 1.22; 4.34  LDD2145 
RuvB-like 1 (RUVBL1) LDTP13816 0.58  LDD2145 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.82  LDD2145 
S-formylglutathione hydrolase (ESD) LDTP02521 4.55  LDD2145 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 0.25  LDD2145 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 3.77  LDD2145 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 8.57; 6.42  LDD2145 
Septin-7 (SEPTIN7) LDTP06513 0.19  LDD2145 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 0.30  LDD2145 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 2.18; 0.80; 1.25 ...  LDD2145 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 0.97  LDD2145 
Serine palmitoyltransferase 2 (SPTLC2) LDTP00598 0.38  LDD2145 
Serine--tRNA ligase, cytoplasmic (SARS1) LDTP04265 4.83  LDD2145 
Serine/threonine-protein kinase PRP4 homolog (PRPF4B) LDTP05911 1.65  LDD2145 
Serine/threonine-protein kinase WNK1 (WNK1) LDTP11909 0.13  LDD2145 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 0.19; 0.15  LDD2145 
Serine/threonine-protein phosphatase 4 regulatory subunit 3B (PPP4R3B) LDTP07034 1.95  LDD2145 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 5.98; 3.04  LDD2145 
Sialic acid synthase (NANS) LDTP12473 0.43  LDD2145 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 1.01  LDD2145 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 6.24; 4.09  LDD2145 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 1.40; 1.33; 3.86 ...  LDD2145 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 4.81; 6.62  LDD2145 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 7.38  LDD2145 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 0.64; 2.41; 0.85 ...  LDD2145 
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1) LDTP04566 1.29  LDD2145 
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (OXCT1) LDTP04715 0.22; 0.23  LDD2145 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 1.81  LDD2145 
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) LDTP00931 0.64; 2.67  LDD2145 
Thimet oligopeptidase (THOP1) LDTP04542 1.25; 0.25  LDD2145 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 1.08  LDD2145 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 0.18  LDD2145 
Thioredoxin reductase 2, mitochondrial (TXNRD2) LDTP12297 0.25  LDD2145 
Thymidylate kinase (DTYMK) LDTP03258 3.55  LDD2145 
Transaldolase (TALDO1) LDTP03847 0.55  LDD2145 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 1.79; 4.81  LDD2145 
Transforming protein RhoA (RHOA) LDTP04927 11.71  LDD2145 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.19; 0.19  LDD2145 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 1.35; 0.20  LDD2145 
Triokinase/FMN cyclase (TKFC) LDTP06779 5.12  LDD2145 
Triosephosphate isomerase (TPI1) LDTP04851 0.17; 0.19; 0.06 ...  LDD2145 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 0.24; 8.03  LDD2145 
Tyrosine-protein kinase receptor UFO (AXL) LDTP03542 2.90  LDD2145 
Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) LDTP02935 2.86  LDD2145 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 1.14; 0.33; 0.10  LDD2145 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 3.10  LDD2145 
Ubiquitin-conjugating enzyme E2 S (UBE2S) LDTP06621 2.14  LDD2145 
Ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1) LDTP05853 0.11  LDD2145 
Ubiquitin-like domain-containing CTD phosphatase 1 (UBLCP1) LDTP09629 0.78  LDD2145 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 3.38; 0.90  LDD2145 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 9.62  LDD2145 
Unconventional myosin-Va (MYO5A) LDTP14061 2.53  LDD2145 
Urokinase-type plasminogen activator (PLAU) LDTP01799 1.99  LDD2145 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.10; 8.59  LDD2145 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 1.09  LDD2145 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 1.01  LDD2145 
WD repeat-containing protein 82 (WDR82) LDTP07715 3.49  LDD2145 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 0.39; 3.21  LDD2145 
Xaa-Pro dipeptidase (PEPD) LDTP02639 0.19  LDD2145 
Xanthine dehydrogenase/oxidase (XDH) LDTP04145 0.17  LDD2145 
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⏷ Show the Full List of 335 Enzyme
113 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein gamma (YWHAG) LDTP04953 0.29  LDD2145 
14-3-3 protein theta (YWHAQ) LDTP03385 5.35; 7.72  LDD2145 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.54  LDD2145 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 0.85  LDD2145 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 6.35  LDD2145 
Annexin A1 (ANXA1) LDTP02010 0.98; 0.52  LDD2145 
Annexin A6 (ANXA6) LDTP02247 6.39  LDD2145 
AP-1 complex subunit beta-1 (AP1B1) LDTP05625 2.15  LDD2145 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 1.00; 0.21; 0.46  LDD2145 
AP-2 complex subunit alpha-2 (AP2A2) LDTP01477 0.58  LDD2145 
AP-2 complex subunit mu (AP2M1) LDTP10190 0.45  LDD2145 
Apoptosis regulator BAX (BAX) LDTP05528 2.14  LDD2145 
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) LDTP13490 5.93  LDD2145 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 0.32  LDD2145 
ATP-binding cassette sub-family F member 2 (ABCF2) LDTP18526 0.25  LDD2145 
ATP-binding cassette sub-family F member 3 (ABCF3) LDTP16103 1.87  LDD2145 
B-cell receptor-associated protein 29 (BCAP29) LDTP16201 1.62  LDD2145 
BOS complex subunit NCLN (NCLN) LDTP10036 1.54  LDD2145 
Calreticulin (CALR) LDTP03402 0.41  LDD2145 
CD44 antigen (CD44) LDTP02823 0.55  LDD2145 
Clathrin heavy chain 1 (CLTC) LDTP05252 11.24; 6.01; 2.75  LDD2145 
Clathrin light chain B (CLTB) LDTP02353 2.18  LDD2145 
Copine-3 (CPNE3) LDTP01133 0.13; 0.24  LDD2145 
Cysteine-rich motor neuron 1 protein (CRIM1) LDTP12942 0.78; 6.04  LDD2145 
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) LDTP02504 1.70  LDD2145 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 3.36  LDD2145 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 2.99  LDD2145 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 3.61  LDD2145 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 6.93  LDD2145 
Exportin-1 (XPO1) LDTP00501 4.62  LDD2145 
Exportin-2 (CSE1L) LDTP04662 6.56; 8.26; 2.74 ...  LDD2145 
Fatty acid-binding protein 5 (FABP5) LDTP05292 2.28  LDD2145 
Filamin-A (FLNA) LDTP03107 1.62; 1.67; 2.57 ...  LDD2145 
Filamin-B (FLNB) LDTP01197 1.81; 3.70; 0.45 ...  LDD2145 
Filamin-C (FLNC) LDTP06103 0.30; 0.21; 3.16 ...  LDD2145 
Galectin-3 (LGALS3) LDTP02929 0.20  LDD2145 
Glioma pathogenesis-related protein 1 (GLIPR1) LDTP14694 0.14  LDD2145 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 0.34; 0.74  LDD2145 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 0.51  LDD2145 
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (GNAS) LDTP05040 8.20  LDD2145 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 1.64  LDD2145 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 2.74; 4.29  LDD2145 
Hypoxia up-regulated protein 1 (HYOU1) LDTP14066 0.19  LDD2145 
Importin subunit alpha-7 (KPNA6) LDTP01031 3.21  LDD2145 
Importin subunit beta-1 (KPNB1) LDTP06242 5.13  LDD2145 
Importin-4 (IPO4) LDTP09515 4.08  LDD2145 
Importin-5 (IPO5) LDTP00266 13.46  LDD2145 
Importin-7 (IPO7) LDTP01574 6.79  LDD2145 
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) LDTP06153 5.89; 1.22  LDD2145 
Integral membrane protein 2B (ITM2B) LDTP13833 2.10  LDD2145 
Integrin alpha-6 (ITGA6) LDTP03211 1.61  LDD2145 
Integrin alpha-V (ITGAV) LDTP02166 0.39  LDD2145 
Integrin beta-1 (ITGB1) LDTP02122 0.29  LDD2145 
Kinesin-1 heavy chain (KIF5B) LDTP03664 1.37; 0.19  LDD2145 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 2.40  LDD2145 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 0.89  LDD2145 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 1.87  LDD2145 
MICOS complex subunit MIC10 (MICOS10) LDTP07191 1.67  LDD2145 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 3.28; 0.40  LDD2145 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 3.70  LDD2145 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 2.85  LDD2145 
Myoferlin (MYOF) LDTP12916 3.06; 0.29; 1.08 ...  LDD2145 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 2.65  LDD2145 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 2.07  LDD2145 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 8.12  LDD2145 
Nuclear pore complex protein Nup88 (NUP88) LDTP10897 4.46; 2.90  LDD2145 
Nucleoporin NDC1 (NDC1) LDTP11213 3.65  LDD2145 
Nucleoporin Nup37 (NUP37) LDTP09203 1.46  LDD2145 
Nucleoporin Nup43 (NUP43) LDTP09202 0.14  LDD2145 
Nucleoprotein TPR (TPR) LDTP02612 6.21; 0.91; 1.37  LDD2145 
Podocalyxin (PODXL) LDTP00321 0.59  LDD2145 
Prohibitin 1 (PHB1) LDTP03717 0.23  LDD2145 
Prosaposin (PSAP) LDTP02215 6.35  LDD2145 
Protein RFT1 homolog (RFT1) LDTP10073 2.52  LDD2145 
Protein S100-A10 (S100A10) LDTP04885 9.95  LDD2145 
Protein SEC13 homolog (SEC13) LDTP04707 0.36  LDD2145 
Protein transport protein Sec31A (SEC31A) LDTP01478 1.01  LDD2145 
Protein transport protein Sec61 subunit beta (SEC61B) LDTP04866 6.90  LDD2145 
Protein transport protein Sec61 subunit gamma (SEC61G) LDTP04850 10.04  LDD2145 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 2.47  LDD2145 
Serine incorporator 3 (SERINC3) LDTP05913 4.36  LDD2145 
Signal recognition particle 14 kDa protein (SRP14) LDTP03837 3.33  LDD2145 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 1.19; 3.33  LDD2145 
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) LDTP02068 1.40  LDD2145 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 8.90  LDD2145 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 3.30  LDD2145 
Sorting nexin-12 (SNX12) LDTP13634 1.36  LDD2145 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 0.11; 0.09; 4.72 ...  LDD2145 
Splicing factor, arginine/serine-rich 19 (SCAF1) LDTP12030 0.89  LDD2145 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 7.19  LDD2145 
Syntenin-1 (SDCBP) LDTP00310 0.51  LDD2145 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.22; 4.00; 3.65 ...  LDD2145 
Talin-1 (TLN1) LDTP14031 0.91; 0.50; 4.13 ...  LDD2145 
THO complex subunit 1 (THOC1) LDTP10317 7.52; 3.00  LDD2145 
THO complex subunit 6 homolog (THOC6) LDTP08315 1.94  LDD2145 
THO complex subunit 7 homolog (THOC7) LDTP07397 5.32  LDD2145 
Tissue factor (F3) LDTP02686 0.93  LDD2145 
Transferrin receptor protein 1 (TFRC) LDTP01969 1.08  LDD2145 
Translocation protein SEC62 (SEC62) LDTP15838 0.71; 0.30  LDD2145 
Translocation protein SEC63 homolog (SEC63) LDTP13243 2.62  LDD2145 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 1.09  LDD2145 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 7.98  LDD2145 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 0.35  LDD2145 
Transmembrane protein 214 (TMEM214) LDTP07477 6.90  LDD2145 
Transmembrane protein 33 (TMEM33) LDTP04787 7.66  LDD2145 
Unconventional myosin-Ic (MYO1C) LDTP00196 0.58  LDD2145 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 0.48  LDD2145 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 4.73  LDD2145 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 1.86  LDD2145 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 3.90; 0.81  LDD2145 
Vesicle-associated membrane protein-associated protein B/C (VAPB) LDTP01556 4.97  LDD2145 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 2.42  LDD2145 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 4.13  LDD2145 
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⏷ Show the Full List of 113 Transporter and channel
18 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CCAAT/enhancer-binding protein beta (CEBPB) LDTP02914 3.47  LDD2145 
Cell division cycle 5-like protein (CDC5L) LDTP10868 7.24  LDD2145 
COUP transcription factor 1 (NR2F1) LDTP02501 2.96  LDD2145 
FACT complex subunit SSRP1 (SSRP1) LDTP05577 0.67  LDD2145 
Forkhead box protein K1 (FOXK1) LDTP05201 4.48  LDD2145 
Gamma-interferon-inducible protein 16 (IFI16) LDTP06602 5.24  LDD2145 
General transcription factor II-I (GTF2I) LDTP05101 3.70  LDD2145 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 6.88; 1.65; 1.90  LDD2145 
NF-kappa-B-repressing factor (NKRF) LDTP00576 5.21  LDD2145 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 6.63; 2.66  LDD2145 
Nuclear autoantigen Sp-100 (SP100) LDTP03237 1.57  LDD2145 
Nuclear factor 1 C-type (NFIC) LDTP02296 13.29  LDD2145 
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4) LDTP06231 5.37  LDD2145 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 5.80  LDD2145 
SWI/SNF complex subunit SMARCC1 (SMARCC1) LDTP09932 0.35  LDD2145 
T-cell leukemia homeobox protein 1 (TLX1) LDTP03588 5.85  LDD2145 
THAP domain-containing protein 11 (THAP11) LDTP10262 1.52  LDD2145 
Zinc finger protein 212 (ZNF212) LDTP13188 0.96  LDD2145 
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⏷ Show the Full List of 18 Transcription factor
1 GPCR Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Retinoic acid-induced protein 3 (GPRC5A) LDTP09206 0.82  LDD2145 
------------------------------------------------------------------------------------
3 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Basigin (BSG) LDTP03772 1.54  LDD2145 
CMRF35-like molecule 2 (CD300E) LDTP06824 1.89  LDD2145 
Programmed cell death 1 ligand 1 (CD274) LDTP12930 8.54  LDD2145 
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2 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Interleukin-6 receptor subunit beta (IL6ST) LDTP03881 6.62; 0.14  LDD2145 
Tumor necrosis factor receptor superfamily member 5 (CD40) LDTP03340 1.24  LDD2145 
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331 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 7.02  LDD2145 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 1.04  LDD2145 
5-azacytidine-induced protein 2 (AZI2) LDTP11997 10.13  LDD2145 
60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) LDTP13779 0.69  LDD2145 
A-kinase anchor protein 1, mitochondrial (AKAP1) LDTP09837 2.94  LDD2145 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.35; 1.02  LDD2145 
Actin-like protein 6A (ACTL6A) LDTP01756 0.94; 0.95  LDD2145 
Actin-related protein 2 (ACTR2) LDTP04903 0.14  LDD2145 
Actin-related protein 2/3 complex subunit 1B (ARPC1B) LDTP00550 0.18; 0.90  LDD2145 
Actin-related protein 2/3 complex subunit 2 (ARPC2) LDTP00551 0.29  LDD2145 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 0.33  LDD2145 
Actin-related protein 3 (ACTR3) LDTP04902 0.79  LDD2145 
Actin-related protein T1 (ACTRT1) LDTP09433 7.21  LDD2145 
Activating transcription factor 7-interacting protein 1 (ATF7IP) LDTP07732 0.27  LDD2145 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.20; 0.15  LDD2145 
Alpha-actinin-1 (ACTN1) LDTP02631 0.17; 1.32  LDD2145 
Alpha-parvin (PARVA) LDTP12671 0.61  LDD2145 
Alpha-soluble NSF attachment protein (NAPA) LDTP04647 2.14  LDD2145 
Ankyrin repeat domain-containing protein 17 (ANKRD17) LDTP01155 0.51  LDD2145 
Annexin A3 (ANXA3) LDTP02620 0.21  LDD2145 
BAG family molecular chaperone regulator 2 (BAG2) LDTP01683 0.38  LDD2145 
Bardet-Biedl syndrome 12 protein (BBS12) LDTP07861 0.19  LDD2145 
Barrier-to-autointegration factor (BANF1) LDTP01250 0.27; 0.14  LDD2145 
Calmegin (CLGN) LDTP00493 4.37  LDD2145 
Calpastatin (CAST) LDTP03079 0.34; 3.91  LDD2145 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 3.66  LDD2145 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 10.75  LDD2145 
Caprin-1 (CAPRIN1) LDTP06121 0.34  LDD2145 
Caspase activity and apoptosis inhibitor 1 (CAAP1) LDTP18416 0.84  LDD2145 
Catenin alpha-1 (CTNNA1) LDTP03711 2.73  LDD2145 
Catenin beta-1 (CTNNB1) LDTP03712 0.32  LDD2145 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 1.55; 1.45  LDD2145 
CCN family member 1 (CCN1) LDTP00323 1.71  LDD2145 
CDK-activating kinase assembly factor MAT1 (MNAT1) LDTP04488 0.79  LDD2145 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 3.18  LDD2145 
Charged multivesicular body protein 5 (CHMP5) LDTP12948 4.88  LDD2145 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 6.45  LDD2145 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 7.35  LDD2145 
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) LDTP11718 7.18  LDD2145 
Coactosin-like protein (COTL1) LDTP06024 0.20  LDD2145 
Coatomer subunit beta (COPB1) LDTP04570 9.41; 1.25  LDD2145 
Coatomer subunit beta' (COPB2) LDTP03767 1.96  LDD2145 
Cofilin-1 (CFL1) LDTP03244 9.37; 7.94; 2.32 ...  LDD2145 
Cofilin-2 (CFL2) LDTP13827 1.04  LDD2145 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 0.18  LDD2145 
Complement decay-accelerating factor (CD55) LDTP02253 1.08  LDD2145 
Condensin-2 complex subunit D3 (NCAPD3) LDTP03994 9.12  LDD2145 
Condensin-2 complex subunit G2 (NCAPG2) LDTP08359 0.44  LDD2145 
COP9 signalosome complex subunit 1 (GPS1) LDTP05746 0.14  LDD2145 
Copine-8 (CPNE8) LDTP17607 0.69  LDD2145 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 0.44  LDD2145 
Coronin-1B (CORO1B) LDTP11101 1.43  LDD2145 
Coronin-1C (CORO1C) LDTP13580 6.54; 4.72; 1.09 ...  LDD2145 
Crk-like protein (CRKL) LDTP04092 1.52  LDD2145 
CUB domain-containing protein 1 (CDCP1) LDTP11963 0.11  LDD2145 
CUGBP Elav-like family member 1 (CELF1) LDTP09913 6.50  LDD2145 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 9.35  LDD2145 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.96; 5.30; 3.69 ...  LDD2145 
DAZ-associated protein 1 (DAZAP1) LDTP10271 1.22; 11.05  LDD2145 
Death-inducer obliterator 1 (DIDO1) LDTP11192 7.34  LDD2145 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 4.71; 0.11  LDD2145 
Destrin (DSTN) LDTP04887 6.25  LDD2145 
Disks large homolog 2 (DLG2) LDTP06448 0.20  LDD2145 
DNA damage-binding protein 1 (DDB1) LDTP06543 0.11; 0.20; 0.70  LDD2145 
DnaJ homolog subfamily A member 1 (DNAJA1) LDTP03606 0.88  LDD2145 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 0.22  LDD2145 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 0.68  LDD2145 
Double-strand-break repair protein rad21 homolog (RAD21) LDTP00911 0.13  LDD2145 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 1.64  LDD2145 
Dystonin (DST) LDTP05386 1.47  LDD2145 
Elongation factor 1-delta (EEF1D) LDTP03499 0.63  LDD2145 
Endoplasmic reticulum resident protein 44 (ERP44) LDTP11144 1.39  LDD2145 
Endoplasmin (HSP90B1) LDTP02734 10.22; 0.86  LDD2145 
Epidermal growth factor receptor substrate 15 (EPS15) LDTP03982 0.13  LDD2145 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 0.67  LDD2145 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.78  LDD2145 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.49; 0.31  LDD2145 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 5.27; 6.59  LDD2145 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 0.79  LDD2145 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.26; 0.99  LDD2145 
Eukaryotic translation initiation factor 6 (EIF6) LDTP04743 0.23; 2.47; 0.24 ...  LDD2145 
F-actin-capping protein subunit alpha-1 (CAPZA1) LDTP04544 0.62  LDD2145 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 7.77  LDD2145 
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1) LDTP11544 0.75  LDD2145 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.03  LDD2145 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 1.42; 2.91  LDD2145 
Ferritin light chain (FTL) LDTP01973 0.11  LDD2145 
G-rich sequence factor 1 (GRSF1) LDTP05668 2.18  LDD2145 
Galectin-1 (LGALS1) LDTP02341 4.59; 3.30; 3.51  LDD2145 
General transcription factor IIH subunit 1 (GTF2H1) LDTP03651 9.64  LDD2145 
Gephyrin (GPHN) LDTP12448 0.24; 0.24  LDD2145 
Glycoprotein integral membrane protein 1 (GINM1) LDTP19994 3.92  LDD2145 
Golgi apparatus protein 1 (GLG1) LDTP09920 0.60  LDD2145 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 5.54  LDD2145 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 1.85  LDD2145 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (GNG12) LDTP13120 0.30  LDD2145 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) LDTP05054 0.40  LDD2145 
Guanine nucleotide-binding protein subunit beta-4 (GNB4) LDTP12141 0.76  LDD2145 
H/ACA ribonucleoprotein complex subunit 2 (NHP2) LDTP12754 0.52  LDD2145 
H/ACA ribonucleoprotein complex subunit 3 (NOP10) LDTP12350 0.91  LDD2145 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.20; 0.24; 1.21 ...  LDD2145 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.76; 2.42; 1.20 ...  LDD2145 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 3.96  LDD2145 
Hepatoma-derived growth factor (HDGF) LDTP04483 5.41; 2.06  LDD2145 
Hepatoma-derived growth factor-related protein 2 (HDGFL2) LDTP08081 0.57  LDD2145 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.53  LDD2145 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 1.82  LDD2145 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 1.24; 1.26  LDD2145 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 1.32; 3.18  LDD2145 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 12.87  LDD2145 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 8.16; 1.72; 5.62  LDD2145 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 6.95; 5.31  LDD2145 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 1.98; 0.29; 11.12  LDD2145 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 0.25; 0.25  LDD2145 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.80; 2.40; 0.36 ...  LDD2145 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 0.43  LDD2145 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 1.99  LDD2145 
Histone-binding protein RBBP4 (RBBP4) LDTP05590 0.38  LDD2145 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 0.24; 3.39  LDD2145 
Host cell factor 1 (HCFC1) LDTP04434 0.77  LDD2145 
Inner centromere protein (INCENP) LDTP12432 1.27  LDD2145 
Integrin alpha-2 (ITGA2) LDTP02893 0.17  LDD2145 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 1.30  LDD2145 
Interleukin-17 receptor D (IL17RD) LDTP09211 1.04  LDD2145 
Jupiter microtubule associated homolog 2 (JPT2) LDTP12077 4.43  LDD2145 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 0.16  LDD2145 
Kinectin (KTN1) LDTP08238 3.33  LDD2145 
La-related protein 4B (LARP4B) LDTP09820 0.78  LDD2145 
Large ribosomal subunit protein bL35m (MRPL35) LDTP12894 0.97  LDD2145 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 2.49  LDD2145 
Large ribosomal subunit protein eL15 (RPL15) LDTP04919 0.28  LDD2145 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 3.97  LDD2145 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 3.17; 4.13; 1.01 ...  LDD2145 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 4.61; 3.47  LDD2145 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 3.58  LDD2145 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 1.10  LDD2145 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 8.86; 1.74  LDD2145 
Large ribosomal subunit protein eL36 (RPL36) LDTP14012 0.11  LDD2145 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 11.57  LDD2145 
Large ribosomal subunit protein eL8 (RPL7A) LDTP04990 0.22  LDD2145 
Large ribosomal subunit protein mL38 (MRPL38) LDTP10232 0.88  LDD2145 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 0.40; 0.28; 0.21  LDD2145 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 2.31  LDD2145 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 0.51; 0.90  LDD2145 
Large ribosomal subunit protein uL15m (MRPL15) LDTP16157 1.35  LDD2145 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.74; 0.69  LDD2145 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 9.02; 3.92; 0.91  LDD2145 
Large ribosomal subunit protein uL5 (RPL11) LDTP05026 1.33  LDD2145 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 2.69; 2.19  LDD2145 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 3.20; 3.96; 3.22 ...  LDD2145 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 5.84  LDD2145 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 3.38  LDD2145 
Macrosialin (CD68) LDTP03687 8.36  LDD2145 
Matrin-3 (MATR3) LDTP04027 0.35; 0.17  LDD2145 
Mediator of RNA polymerase II transcription subunit 11 (MED11) LDTP12955 0.30  LDD2145 
Mediator of RNA polymerase II transcription subunit 17 (MED17) LDTP12669 0.17  LDD2145 
Mediator of RNA polymerase II transcription subunit 22 (MED22) LDTP06405 0.22  LDD2145 
Mediator of RNA polymerase II transcription subunit 30 (MED30) LDTP10396 1.06  LDD2145 
Methylosome protein WDR77 (WDR77) LDTP11066 0.30  LDD2145 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 4.17  LDD2145 
Microtubule-associated protein 4 (MAP4) LDTP03404 2.63; 2.85  LDD2145 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 4.43  LDD2145 
Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 4.28  LDD2145 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.65; 2.10  LDD2145 
MKI67 FHA domain-interacting nucleolar phosphoprotein (NIFK) LDTP11457 0.38  LDD2145 
MOB-like protein phocein (MOB4) LDTP13964 0.68; 1.01  LDD2145 
MRG/MORF4L-binding protein (MRGBP) LDTP12658 1.05  LDD2145 
mRNA turnover protein 4 homolog (MRTO4) LDTP16220 0.38; 0.28  LDD2145 
Myb-binding protein 1A (MYBBP1A) LDTP11079 1.04; 4.90  LDD2145 
Myosin light polypeptide 6 (MYL6) LDTP04875 0.92  LDD2145 
NADH dehydrogenase 1 alpha subcomplex assembly factor 4 (NDUFAF4) LDTP12953 6.07  LDD2145 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 2.10  LDD2145 
NHP2-like protein 1 (SNU13) LDTP04708 1.75; 0.14  LDD2145 
NTF2-related export protein 1 (NXT1) LDTP13461 2.15  LDD2145 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 5.02; 0.45  LDD2145 
Nuclear receptor 2C2-associated protein (NR2C2AP) LDTP08338 1.35  LDD2145 
Nuclear receptor coactivator 5 (NCOA5) LDTP12230 0.83  LDD2145 
Nucleolar complex protein 2 homolog (NOC2L) LDTP14011 0.60  LDD2145 
Nucleolar protein 16 (NOP16) LDTP16278 5.17  LDD2145 
Nucleolar protein 56 (NOP56) LDTP00313 0.28  LDD2145 
Nucleolin (NCL) LDTP02990 2.66  LDD2145 
Nucleophosmin (NPM1) LDTP02164 0.08  LDD2145 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 7.63; 1.02  LDD2145 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.59  LDD2145 
Ovarian cancer-related protein 1 (OCR1) LDTP20391 4.16  LDD2145 
Oxysterol-binding protein 1 (OSBP) LDTP03151 0.17  LDD2145 
Paired amphipathic helix protein Sin3a (SIN3A) LDTP10823 0.24; 1.18  LDD2145 
PCNA-associated factor (PCLAF) LDTP06269 2.03  LDD2145 
PDZ and LIM domain protein 1 (PDLIM1) LDTP00193 1.02  LDD2145 
Pentraxin-related protein PTX3 (PTX3) LDTP03345 1.35  LDD2145 
Perilipin-3 (PLIN3) LDTP01021 2.43  LDD2145 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 4.61  LDD2145 
Plastin-2 (LCP1) LDTP02691 0.39; 0.12; 0.38  LDD2145 
Plastin-3 (PLS3) LDTP02692 9.57  LDD2145 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 0.25  LDD2145 
Pleckstrin homology-like domain family B member 2 (PHLDB2) LDTP08172 0.88  LDD2145 
Plectin (PLEC) LDTP06330 7.30; 1.88; 7.53 ...  LDD2145 
Pleiotropic regulator 1 (PLRG1) LDTP00827 0.41; 0.27  LDD2145 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 1.91  LDD2145 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 7.04; 0.35  LDD2145 
Polymerase delta-interacting protein 2 (POLDIP2) LDTP13906 10.24  LDD2145 
Pre-mRNA-processing factor 40 homolog B (PRPF40B) LDTP07485 0.08  LDD2145 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 2.15  LDD2145 
Pre-mRNA-splicing factor ISY1 homolog (ISY1) LDTP13570 1.75  LDD2145 
Prefoldin subunit 5 (PFDN5) LDTP10873 0.28  LDD2145 
Prelamin-A/C (LMNA) LDTP01932 1.45  LDD2145 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 8.80  LDD2145 
Proliferating cell nuclear antigen (PCNA) LDTP02596 4.91  LDD2145 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 4.21; 2.44; 2.84 ...  LDD2145 
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) LDTP08707 5.06  LDD2145 
Proteasomal ubiquitin receptor ADRM1 (ADRM1) LDTP06514 5.41  LDD2145 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 3.97; 0.10  LDD2145 
Proteasome assembly chaperone 2 (PSMG2) LDTP10035 1.56  LDD2145 
Protein CMSS1 (CMSS1) LDTP18287 1.34  LDD2145 
Protein DEK (DEK) LDTP03778 4.74  LDD2145 
Protein ECT2 (ECT2) LDTP12067 3.09  LDD2145 
Protein FAM91A1 (FAM91A1) LDTP15056 2.62  LDD2145 
Protein FAM98B (FAM98B) LDTP06879 3.45  LDD2145 
Protein Hook homolog 3 (HOOK3) LDTP08301 0.22  LDD2145 
Protein LSM12 (LSM12) LDTP06780 5.71; 1.01  LDD2145 
Protein Niban 2 (NIBAN2) LDTP10847 3.38; 5.98  LDD2145 
Protein RCC2 (RCC2) LDTP13020 0.82; 3.42  LDD2145 
Protein SDA1 homolog (SDAD1) LDTP12694 6.21; 1.83  LDD2145 
Protein TASOR 2 (TASOR2) LDTP07241 12.09  LDD2145 
Protein THEM6 (THEM6) LDTP19831 6.05  LDD2145 
Protein unc-13 homolog D (UNC13D) LDTP07888 0.49  LDD2145 
Protein ZNRD2 (ZNRD2) LDTP00916 0.13  LDD2145 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 1.08  LDD2145 
Ras GTPase-activating protein-binding protein 2 (G3BP2) LDTP13647 0.90  LDD2145 
Replication protein A 14 kDa subunit (RPA3) LDTP03723 3.18  LDD2145 
Reticulon-4 (RTN4) LDTP12412 9.33  LDD2145 
Ribosomal L1 domain-containing protein 1 (RSL1D1) LDTP01379 0.54  LDD2145 
Ribosomal protein uL16-like (RPL10L) LDTP10525 6.40  LDD2145 
Ribosomal RNA processing protein 1 homolog A (RRP1) LDTP04729 7.76  LDD2145 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 13.19  LDD2145 
Ribosome biogenesis protein NSA2 homolog (NSA2) LDTP16846 0.59  LDD2145 
Ribosome maturation protein SBDS (SBDS) LDTP13966 2.12; 1.94  LDD2145 
Ribosome-binding protein 1 (RRBP1) LDTP13044 1.98; 2.16  LDD2145 
RNA polymerase-associated protein CTR9 homolog (CTR9) LDTP07563 0.85; 0.27  LDD2145 
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) LDTP03495 0.99  LDD2145 
RNA-binding motif, single-stranded-interacting protein 3 (RBMS3) LDTP07748 0.86  LDD2145 
RNA-binding protein 4B (RBM4B) LDTP11046 2.34  LDD2145 
RNA-binding protein EWS (EWSR1) LDTP05318 1.07; 0.85; 0.68  LDD2145 
RNA-binding protein FUS (FUS) LDTP03775 0.35; 0.64  LDD2145 
RNA-binding protein FXR1 (FXR1) LDTP04395 4.15  LDD2145 
RNA-binding protein Raly (RALY) LDTP13467 2.59  LDD2145 
Scaffold attachment factor B2 (SAFB2) LDTP06054 4.32  LDD2145 
Sequestosome-1 (SQSTM1) LDTP05898 2.08; 0.29  LDD2145 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 6.58  LDD2145 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 0.35  LDD2145 
Serine/arginine-rich splicing factor 11 (SRSF11) LDTP05458 3.50  LDD2145 
Serine/arginine-rich splicing factor 3 (SRSF3) LDTP05197 6.59  LDD2145 
Serine/arginine-rich splicing factor 6 (SRSF6) LDTP05802 1.54  LDD2145 
Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2) LDTP12800 5.28  LDD2145 
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (PPP6R1) LDTP13701 2.23  LDD2145 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 5.91; 5.34; 19.23 ...  LDD2145 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 1.60  LDD2145 
Small nuclear ribonucleoprotein F (SNRPF) LDTP04977 0.26  LDD2145 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 0.18; 0.24  LDD2145 
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) LDTP04983 0.14; 0.19  LDD2145 
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) LDTP02741 0.15  LDD2145 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 3.63; 8.99  LDD2145 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 4.24; 6.09  LDD2145 
Small ribosomal subunit protein eS17 (RPS17) LDTP02302 6.22  LDD2145 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 9.71  LDD2145 
Small ribosomal subunit protein eS27 (RPS27) LDTP03987 6.46  LDD2145 
Small ribosomal subunit protein eS28 (RPS28) LDTP05015 6.96  LDD2145 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 5.58  LDD2145 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 9.49; 4.36  LDD2145 
Small ribosomal subunit protein mS29 (DAP3) LDTP04412 0.20  LDD2145 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 8.43; 2.61  LDD2145 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 5.30  LDD2145 
Small ribosomal subunit protein uS17m (MRPS17) LDTP16269 0.41  LDD2145 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 3.69  LDD2145 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 8.30  LDD2145 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 8.50  LDD2145 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 1.18  LDD2145 
Small ubiquitin-related modifier 1 (SUMO1) LDTP05048 1.00  LDD2145 
Smoothelin (SMTN) LDTP04590 3.06  LDD2145 
SNW domain-containing protein 1 (SNW1) LDTP05930 1.77  LDD2145 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 0.18  LDD2145 
Splicing factor 1 (SF1) LDTP06429 0.33  LDD2145 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 5.27; 3.24  LDD2145 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 2.82; 0.48; 0.14  LDD2145 
Splicing factor 3B subunit 6 (SF3B6) LDTP13970 2.58  LDD2145 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 10.41  LDD2145 
SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) LDTP11645 2.10  LDD2145 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 3.84; 0.58; 1.40 ...  LDD2145 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 2.53; 1.04; 2.89 ...  LDD2145 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 0.08  LDD2145 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 8.32  LDD2145 
Structural maintenance of chromosomes protein 3 (SMC3) LDTP13760 0.29; 0.56; 0.16  LDD2145 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 0.36  LDD2145 
Structural maintenance of chromosomes protein 5 (SMC5) LDTP08618 0.57  LDD2145 
SURP and G-patch domain-containing protein 2 (SUGP2) LDTP08578 4.41  LDD2145 
Synaptophysin-like protein 1 (SYPL1) LDTP06557 2.01  LDD2145 
Syntaxin-7 (STX7) LDTP00632 0.32  LDD2145 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 0.82  LDD2145 
T-complex protein 1 subunit beta (CCT2) LDTP05113 6.39  LDD2145 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 5.24; 2.61; 0.23  LDD2145 
T-complex protein 1 subunit eta (CCT7) LDTP10990 1.01; 1.64; 1.41  LDD2145 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 2.68; 0.40; 0.55  LDD2145 
T-complex protein 1 subunit theta (CCT8) LDTP04390 1.19  LDD2145 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 6.63  LDD2145 
Targeting protein for Xklp2 (TPX2) LDTP13583 1.66  LDD2145 
Transcription elongation factor A protein-like 4 (TCEAL4) LDTP18149 7.14  LDD2145 
Transducin beta-like protein 2 (TBL2) LDTP16285 4.38  LDD2145 
Transforming acidic coiled-coil-containing protein 1 (TACC1) LDTP01210 0.73  LDD2145 
Transgelin-2 (TAGLN2) LDTP03846 1.30  LDD2145 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 0.07  LDD2145 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.77  LDD2145 
Transmembrane protein 161A (TMEM161A) LDTP12762 4.54  LDD2145 
Transport and Golgi organization protein 6 homolog (TANGO6) LDTP18348 1.71  LDD2145 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 0.43  LDD2145 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 0.43  LDD2145 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 5.61  LDD2145 
U3 small nucleolar RNA-associated protein 6 homolog (UTP6) LDTP12830 6.67  LDD2145 
U3 small nucleolar RNA-interacting protein 2 (RRP9) LDTP00876 0.19  LDD2145 
U5 small nuclear ribonucleoprotein 40 kDa protein (SNRNP40) LDTP10217 0.19  LDD2145 
U6 snRNA-associated Sm-like protein LSm4 (LSM4) LDTP14081 0.33; 0.43  LDD2145 
U6 snRNA-associated Sm-like protein LSm5 (LSM5) LDTP14080 0.29  LDD2145 
Ubiquitin-like protein 5 (UBL5) LDTP11545 2.19  LDD2145 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 5.07  LDD2145 
Urokinase plasminogen activator surface receptor (PLAUR) LDTP05404 0.58  LDD2145 
Vigilin (HDLBP) LDTP05239 5.81  LDD2145 
Vimentin (VIM) LDTP02297 8.57  LDD2145 
Vinculin (VCL) LDTP02946 0.18; 0.20; 0.09 ...  LDD2145 
WD repeat-containing protein 1 (WDR1) LDTP01118 0.31; 3.10  LDD2145 
WD repeat-containing protein 43 (WDR43) LDTP06305 8.01  LDD2145 
WD40 repeat-containing protein SMU1 (SMU1) LDTP06726 0.51; 0.66  LDD2145 
Zinc finger RNA-binding protein (ZFR) LDTP15762 5.52; 3.77; 0.37  LDD2145 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 5 mM
Quantitative Method Isotope tag
Experimemt Name ISO-TOP ABPP
Competitor Name Nucleophilic fragment 5b
Competitor Concentration 0.5 mM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD2145  Download The Altas

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761