Details of the Target
General Information of Target
Target ID | LDTP15838 | |||||
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Target Name | Translocation protein SEC62 (SEC62) | |||||
Gene Name | SEC62 | |||||
Gene ID | 7095 | |||||
Synonyms |
TLOC1; Translocation protein SEC62; Translocation protein 1; TP-1; hTP-1 |
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3D Structure | ||||||
Sequence |
MGTWILFACLVGAAFAMPLPPHPGHPGYINFSYENSHSQAINVDRIALVLTPLKWYQSMI
RPPYSSYGYEPMGGWLHHQIIPVVSQQHPLTHTLQSHHHIPVVPAQQPRVRQQALMPVPG QQSMTPTQHHQPNLPLPAQQPFQPQPVQPQPHQPMQPQPPVQPMQPLLPQPPLPPMFPLR PLPPILPDLHLEAWPATDKTKQEEVD |
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Target Bioclass |
Transporter and channel
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Family |
SEC62 family
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Subcellular location |
Endoplasmic reticulum membrane
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Function |
Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen.
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Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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CHEMBL5175495 Probe Info |
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10.35 | LDD0196 | [1] | |
TG42 Probe Info |
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10.65 | LDD0326 | [2] | |
TH211 Probe Info |
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Y102(18.11) | LDD0260 | [3] | |
STPyne Probe Info |
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K22(0.96); K26(3.47); K60(4.19); K65(10.00) | LDD0277 | [4] | |
IPM Probe Info |
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N.A. | LDD0241 | [5] | |
m-APA Probe Info |
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11.90 | LDD0403 | [6] | |
BTD Probe Info |
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C32(1.55); C82(1.15) | LDD1700 | [7] | |
Curcusone 37 Probe Info |
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2.25 | LDD0188 | [8] | |
HPAP Probe Info |
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4.33 | LDD0062 | [9] | |
Alkyne-RA190 Probe Info |
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2.51 | LDD0300 | [10] | |
DBIA Probe Info |
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C82(1.12) | LDD0080 | [11] | |
ATP probe Probe Info |
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K19(0.00); K22(0.00); K26(0.00) | LDD0199 | [12] | |
4-Iodoacetamidophenylacetylene Probe Info |
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C82(0.00); C55(0.00) | LDD0038 | [13] | |
IA-alkyne Probe Info |
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C32(0.00); C82(0.00) | LDD0032 | [14] | |
Lodoacetamide azide Probe Info |
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C55(0.00); C82(0.00) | LDD0037 | [13] | |
PF-06672131 Probe Info |
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N.A. | LDD0152 | [15] | |
SF Probe Info |
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N.A. | LDD0028 | [16] | |
TFBX Probe Info |
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C82(0.00); C55(0.00) | LDD0148 | [17] | |
Acrolein Probe Info |
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C55(0.00); C32(0.00); C82(0.00) | LDD0217 | [18] | |
Cinnamaldehyde Probe Info |
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N.A. | LDD0220 | [18] | |
Crotonaldehyde Probe Info |
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C82(0.00); C55(0.00); C32(0.00); H42(0.00) | LDD0219 | [18] | |
Methacrolein Probe Info |
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C55(0.00); C82(0.00); C32(0.00) | LDD0218 | [18] | |
W1 Probe Info |
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N.A. | LDD0236 | [5] | |
AOyne Probe Info |
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8.10 | LDD0443 | [19] | |
NAIA_5 Probe Info |
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C55(0.00); C32(0.00) | LDD2223 | [20] |
PAL-AfBPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
DR-1 Probe Info |
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2.83 | LDD0398 | [21] | |
C040 Probe Info |
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10.34 | LDD1740 | [22] | |
C056 Probe Info |
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17.03 | LDD1753 | [22] | |
C091 Probe Info |
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11.47 | LDD1782 | [22] | |
C159 Probe Info |
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7.57 | LDD1839 | [22] | |
C161 Probe Info |
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9.78 | LDD1841 | [22] | |
C218 Probe Info |
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13.09 | LDD1892 | [22] | |
C287 Probe Info |
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9.06 | LDD1957 | [22] | |
C289 Probe Info |
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25.99 | LDD1959 | [22] | |
C296 Probe Info |
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11.47 | LDD1966 | [22] | |
C349 Probe Info |
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9.85 | LDD2010 | [22] | |
C350 Probe Info |
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23.59 | LDD2011 | [22] | |
C362 Probe Info |
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27.28 | LDD2023 | [22] | |
FFF probe11 Probe Info |
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20.00 | LDD0471 | [23] | |
OEA-DA Probe Info |
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13.80 | LDD0046 | [24] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0519 | 1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one | MDA-MB-231 | C32(0.67) | LDD2112 | [7] |
LDCM0524 | 2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide | MDA-MB-231 | C82(1.13); C32(0.62) | LDD2117 | [7] |
LDCM0558 | 2-Cyano-N-phenylacetamide | MDA-MB-231 | C82(1.83); C32(1.00); C55(1.23) | LDD2152 | [7] |
LDCM0510 | 3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile | MDA-MB-231 | C32(1.46) | LDD2103 | [7] |
LDCM0538 | 4-(Cyanoacetyl)morpholine | MDA-MB-231 | C32(0.95); C55(0.63) | LDD2131 | [7] |
LDCM0214 | AC1 | HEK-293T | C55(0.90) | LDD1507 | [25] |
LDCM0216 | AC100 | HCT 116 | C82(1.12) | LDD0533 | [11] |
LDCM0217 | AC101 | HCT 116 | C82(0.78) | LDD0534 | [11] |
LDCM0218 | AC102 | HCT 116 | C82(0.66) | LDD0535 | [11] |
LDCM0219 | AC103 | HCT 116 | C82(0.82) | LDD0536 | [11] |
LDCM0220 | AC104 | HCT 116 | C82(0.66) | LDD0537 | [11] |
LDCM0221 | AC105 | HCT 116 | C82(0.49) | LDD0538 | [11] |
LDCM0222 | AC106 | HCT 116 | C82(0.66) | LDD0539 | [11] |
LDCM0223 | AC107 | HCT 116 | C82(0.85) | LDD0540 | [11] |
LDCM0224 | AC108 | HCT 116 | C82(0.89) | LDD0541 | [11] |
LDCM0225 | AC109 | HCT 116 | C82(1.03) | LDD0542 | [11] |
LDCM0227 | AC110 | HCT 116 | C82(0.68) | LDD0544 | [11] |
LDCM0228 | AC111 | HCT 116 | C82(0.98) | LDD0545 | [11] |
LDCM0229 | AC112 | HCT 116 | C82(0.70) | LDD0546 | [11] |
LDCM0230 | AC113 | HCT 116 | C82(1.17) | LDD0547 | [11] |
LDCM0231 | AC114 | HCT 116 | C82(1.02) | LDD0548 | [11] |
LDCM0232 | AC115 | HCT 116 | C82(1.01) | LDD0549 | [11] |
LDCM0233 | AC116 | HCT 116 | C82(0.71) | LDD0550 | [11] |
LDCM0234 | AC117 | HCT 116 | C82(0.88) | LDD0551 | [11] |
LDCM0235 | AC118 | HCT 116 | C82(0.86) | LDD0552 | [11] |
LDCM0236 | AC119 | HCT 116 | C82(0.93) | LDD0553 | [11] |
LDCM0238 | AC120 | HCT 116 | C82(0.84) | LDD0555 | [11] |
LDCM0239 | AC121 | HCT 116 | C82(1.13) | LDD0556 | [11] |
LDCM0240 | AC122 | HCT 116 | C82(1.48) | LDD0557 | [11] |
LDCM0241 | AC123 | HCT 116 | C82(0.77) | LDD0558 | [11] |
LDCM0242 | AC124 | HCT 116 | C82(1.38) | LDD0559 | [11] |
LDCM0243 | AC125 | HCT 116 | C82(1.12) | LDD0560 | [11] |
LDCM0244 | AC126 | HCT 116 | C82(1.16) | LDD0561 | [11] |
LDCM0245 | AC127 | HCT 116 | C82(0.94) | LDD0562 | [11] |
LDCM0246 | AC128 | HCT 116 | C82(0.47) | LDD0563 | [11] |
LDCM0247 | AC129 | HCT 116 | C82(0.59) | LDD0564 | [11] |
LDCM0249 | AC130 | HCT 116 | C82(0.57) | LDD0566 | [11] |
LDCM0250 | AC131 | HCT 116 | C82(0.51) | LDD0567 | [11] |
LDCM0251 | AC132 | HCT 116 | C82(0.58) | LDD0568 | [11] |
LDCM0252 | AC133 | HCT 116 | C82(0.63) | LDD0569 | [11] |
LDCM0253 | AC134 | HCT 116 | C82(0.75) | LDD0570 | [11] |
LDCM0254 | AC135 | HCT 116 | C82(0.80) | LDD0571 | [11] |
LDCM0255 | AC136 | HCT 116 | C82(0.71) | LDD0572 | [11] |
LDCM0256 | AC137 | HCT 116 | C82(0.55) | LDD0573 | [11] |
LDCM0257 | AC138 | HCT 116 | C82(0.51) | LDD0574 | [11] |
LDCM0258 | AC139 | HCT 116 | C82(0.70) | LDD0575 | [11] |
LDCM0260 | AC140 | HCT 116 | C82(0.74) | LDD0577 | [11] |
LDCM0261 | AC141 | HCT 116 | C82(0.66) | LDD0578 | [11] |
LDCM0262 | AC142 | HCT 116 | C82(0.88) | LDD0579 | [11] |
LDCM0263 | AC143 | HCT 116 | C82(0.91) | LDD0580 | [11] |
LDCM0264 | AC144 | HCT 116 | C82(0.50) | LDD0581 | [11] |
LDCM0265 | AC145 | HCT 116 | C82(0.64) | LDD0582 | [11] |
LDCM0266 | AC146 | HCT 116 | C82(0.64) | LDD0583 | [11] |
LDCM0267 | AC147 | HCT 116 | C82(0.58) | LDD0584 | [11] |
LDCM0268 | AC148 | HCT 116 | C82(0.41) | LDD0585 | [11] |
LDCM0269 | AC149 | HCT 116 | C82(0.55) | LDD0586 | [11] |
LDCM0271 | AC150 | HCT 116 | C82(0.76) | LDD0588 | [11] |
LDCM0272 | AC151 | HCT 116 | C82(0.80) | LDD0589 | [11] |
LDCM0273 | AC152 | HCT 116 | C82(0.50) | LDD0590 | [11] |
LDCM0274 | AC153 | HCT 116 | C82(0.39) | LDD0591 | [11] |
LDCM0621 | AC154 | HCT 116 | C82(0.53) | LDD2158 | [11] |
LDCM0622 | AC155 | HCT 116 | C82(0.53) | LDD2159 | [11] |
LDCM0623 | AC156 | HCT 116 | C82(0.76) | LDD2160 | [11] |
LDCM0624 | AC157 | HCT 116 | C82(0.83) | LDD2161 | [11] |
LDCM0276 | AC17 | HEK-293T | C55(0.83) | LDD1515 | [25] |
LDCM0281 | AC21 | HEK-293T | C55(1.03) | LDD1520 | [25] |
LDCM0285 | AC25 | HEK-293T | C55(0.95) | LDD1524 | [25] |
LDCM0289 | AC29 | HEK-293T | C55(1.07) | LDD1528 | [25] |
LDCM0294 | AC33 | HEK-293T | C55(0.89) | LDD1533 | [25] |
LDCM0298 | AC37 | HEK-293T | C55(1.07) | LDD1537 | [25] |
LDCM0303 | AC41 | HEK-293T | C55(0.89) | LDD1542 | [25] |
LDCM0307 | AC45 | HEK-293T | C55(1.03) | LDD1546 | [25] |
LDCM0311 | AC49 | HEK-293T | C55(0.87) | LDD1550 | [25] |
LDCM0312 | AC5 | HEK-293T | C55(1.05) | LDD1551 | [25] |
LDCM0316 | AC53 | HEK-293T | C55(1.03) | LDD1555 | [25] |
LDCM0320 | AC57 | HEK-293T | C55(0.78) | LDD1559 | [25] |
LDCM0325 | AC61 | HEK-293T | C55(0.95) | LDD1564 | [25] |
LDCM0332 | AC68 | HCT 116 | C82(1.17) | LDD0649 | [11] |
LDCM0333 | AC69 | HCT 116 | C82(0.94) | LDD0650 | [11] |
LDCM0335 | AC70 | HCT 116 | C82(0.72) | LDD0652 | [11] |
LDCM0336 | AC71 | HCT 116 | C82(1.35) | LDD0653 | [11] |
LDCM0337 | AC72 | HCT 116 | C82(1.11) | LDD0654 | [11] |
LDCM0338 | AC73 | HCT 116 | C82(0.66) | LDD0655 | [11] |
LDCM0339 | AC74 | HCT 116 | C82(0.77) | LDD0656 | [11] |
LDCM0340 | AC75 | HCT 116 | C82(0.59) | LDD0657 | [11] |
LDCM0341 | AC76 | HCT 116 | C82(0.86) | LDD0658 | [11] |
LDCM0342 | AC77 | HCT 116 | C82(0.82) | LDD0659 | [11] |
LDCM0343 | AC78 | HCT 116 | C82(1.97) | LDD0660 | [11] |
LDCM0344 | AC79 | HCT 116 | C82(0.94) | LDD0661 | [11] |
LDCM0346 | AC80 | HCT 116 | C82(0.90) | LDD0663 | [11] |
LDCM0347 | AC81 | HCT 116 | C82(3.40) | LDD0664 | [11] |
LDCM0348 | AC82 | HCT 116 | C82(0.31) | LDD0665 | [11] |
LDCM0365 | AC98 | HCT 116 | C82(0.31) | LDD0682 | [11] |
LDCM0366 | AC99 | HCT 116 | C82(0.77) | LDD0683 | [11] |
LDCM0545 | Acetamide | MDA-MB-231 | C32(0.78); C55(0.96) | LDD2138 | [7] |
LDCM0520 | AKOS000195272 | MDA-MB-231 | C32(0.98); C55(1.01) | LDD2113 | [7] |
LDCM0248 | AKOS034007472 | HEK-293T | C55(1.04) | LDD1511 | [25] |
LDCM0356 | AKOS034007680 | HEK-293T | C55(0.87) | LDD1570 | [25] |
LDCM0156 | Aniline | NCI-H1299 | 11.90 | LDD0403 | [6] |
LDCM0498 | BS-3668 | MDA-MB-231 | C32(0.66) | LDD2091 | [7] |
LDCM0108 | Chloroacetamide | HeLa | C55(0.00); C32(0.00) | LDD0222 | [18] |
LDCM0367 | CL1 | PaTu 8988t | C82(1.03) | LDD1246 | [11] |
LDCM0368 | CL10 | PaTu 8988t | C82(0.60) | LDD1247 | [11] |
LDCM0379 | CL11 | PaTu 8988t | C82(0.79) | LDD1258 | [11] |
LDCM0390 | CL12 | PaTu 8988t | C82(0.68) | LDD1269 | [11] |
LDCM0400 | CL13 | PaTu 8988t | C82(0.49) | LDD1279 | [11] |
LDCM0401 | CL14 | PaTu 8988t | C82(0.39) | LDD1280 | [11] |
LDCM0402 | CL15 | PaTu 8988t | C82(0.75) | LDD1281 | [11] |
LDCM0403 | CL16 | PaTu 8988t | C82(1.33) | LDD1282 | [11] |
LDCM0404 | CL17 | PaTu 8988t | C82(0.71) | LDD1283 | [11] |
LDCM0405 | CL18 | PaTu 8988t | C82(0.93) | LDD1284 | [11] |
LDCM0406 | CL19 | PaTu 8988t | C82(0.80) | LDD1285 | [11] |
LDCM0407 | CL2 | PaTu 8988t | C82(0.78) | LDD1286 | [11] |
LDCM0408 | CL20 | PaTu 8988t | C82(0.75) | LDD1287 | [11] |
LDCM0409 | CL21 | PaTu 8988t | C82(0.81) | LDD1288 | [11] |
LDCM0410 | CL22 | PaTu 8988t | C82(0.63) | LDD1289 | [11] |
LDCM0411 | CL23 | PaTu 8988t | C82(0.88) | LDD1290 | [11] |
LDCM0412 | CL24 | PaTu 8988t | C82(0.96) | LDD1291 | [11] |
LDCM0413 | CL25 | PaTu 8988t | C82(0.57) | LDD1292 | [11] |
LDCM0414 | CL26 | PaTu 8988t | C82(0.79) | LDD1293 | [11] |
LDCM0415 | CL27 | PaTu 8988t | C82(0.54) | LDD1294 | [11] |
LDCM0416 | CL28 | PaTu 8988t | C82(0.63) | LDD1295 | [11] |
LDCM0417 | CL29 | PaTu 8988t | C82(0.94) | LDD1296 | [11] |
LDCM0418 | CL3 | PaTu 8988t | C82(1.27) | LDD1297 | [11] |
LDCM0419 | CL30 | PaTu 8988t | C82(0.72) | LDD1298 | [11] |
LDCM0420 | CL31 | HCT 116 | C82(0.81) | LDD0737 | [11] |
LDCM0421 | CL32 | HCT 116 | C82(1.68) | LDD0738 | [11] |
LDCM0422 | CL33 | HCT 116 | C82(1.53) | LDD0739 | [11] |
LDCM0423 | CL34 | HCT 116 | C82(0.95) | LDD0740 | [11] |
LDCM0424 | CL35 | HCT 116 | C82(1.08) | LDD0741 | [11] |
LDCM0425 | CL36 | HCT 116 | C82(1.09) | LDD0742 | [11] |
LDCM0426 | CL37 | HCT 116 | C82(1.27) | LDD0743 | [11] |
LDCM0428 | CL39 | HCT 116 | C82(1.04) | LDD0745 | [11] |
LDCM0429 | CL4 | PaTu 8988t | C82(2.04) | LDD1308 | [11] |
LDCM0430 | CL40 | HCT 116 | C82(0.88) | LDD0747 | [11] |
LDCM0431 | CL41 | HCT 116 | C82(1.10) | LDD0748 | [11] |
LDCM0432 | CL42 | HCT 116 | C82(1.07) | LDD0749 | [11] |
LDCM0433 | CL43 | HCT 116 | C82(1.07) | LDD0750 | [11] |
LDCM0434 | CL44 | HCT 116 | C82(1.11) | LDD0751 | [11] |
LDCM0435 | CL45 | HCT 116 | C82(1.10) | LDD0752 | [11] |
LDCM0436 | CL46 | HCT 116 | C82(0.97) | LDD0753 | [11] |
LDCM0437 | CL47 | HCT 116 | C82(1.30) | LDD0754 | [11] |
LDCM0438 | CL48 | HCT 116 | C82(1.14) | LDD0755 | [11] |
LDCM0439 | CL49 | HCT 116 | C82(1.10) | LDD0756 | [11] |
LDCM0440 | CL5 | PaTu 8988t | C82(0.53) | LDD1319 | [11] |
LDCM0441 | CL50 | HCT 116 | C82(0.97) | LDD0758 | [11] |
LDCM0442 | CL51 | HCT 116 | C82(1.18) | LDD0759 | [11] |
LDCM0443 | CL52 | HCT 116 | C82(1.11) | LDD0760 | [11] |
LDCM0444 | CL53 | HCT 116 | C82(1.01) | LDD0761 | [11] |
LDCM0445 | CL54 | HCT 116 | C82(0.95) | LDD0762 | [11] |
LDCM0446 | CL55 | HCT 116 | C82(0.98) | LDD0763 | [11] |
LDCM0447 | CL56 | HCT 116 | C82(0.89) | LDD0764 | [11] |
LDCM0448 | CL57 | HCT 116 | C82(1.07) | LDD0765 | [11] |
LDCM0449 | CL58 | HCT 116 | C82(1.34) | LDD0766 | [11] |
LDCM0450 | CL59 | HCT 116 | C82(0.93) | LDD0767 | [11] |
LDCM0451 | CL6 | PaTu 8988t | C82(0.66) | LDD1330 | [11] |
LDCM0452 | CL60 | HCT 116 | C82(0.76) | LDD0769 | [11] |
LDCM0453 | CL61 | HCT 116 | C82(0.94) | LDD0770 | [11] |
LDCM0454 | CL62 | HCT 116 | C82(0.93) | LDD0771 | [11] |
LDCM0455 | CL63 | HCT 116 | C82(1.25) | LDD0772 | [11] |
LDCM0456 | CL64 | HCT 116 | C82(0.85) | LDD0773 | [11] |
LDCM0457 | CL65 | HCT 116 | C82(0.94) | LDD0774 | [11] |
LDCM0458 | CL66 | HCT 116 | C82(0.81) | LDD0775 | [11] |
LDCM0459 | CL67 | HCT 116 | C82(0.80) | LDD0776 | [11] |
LDCM0460 | CL68 | HCT 116 | C82(0.99) | LDD0777 | [11] |
LDCM0461 | CL69 | HCT 116 | C82(1.52) | LDD0778 | [11] |
LDCM0462 | CL7 | PaTu 8988t | C82(0.63) | LDD1341 | [11] |
LDCM0463 | CL70 | HCT 116 | C82(1.08) | LDD0780 | [11] |
LDCM0464 | CL71 | HCT 116 | C82(0.80) | LDD0781 | [11] |
LDCM0465 | CL72 | HCT 116 | C82(1.13) | LDD0782 | [11] |
LDCM0466 | CL73 | HCT 116 | C82(0.91) | LDD0783 | [11] |
LDCM0467 | CL74 | HCT 116 | C82(0.76) | LDD0784 | [11] |
LDCM0470 | CL77 | HEK-293T | C55(0.79) | LDD1673 | [25] |
LDCM0473 | CL8 | PaTu 8988t | C82(0.70) | LDD1352 | [11] |
LDCM0475 | CL81 | HEK-293T | C55(1.10) | LDD1678 | [25] |
LDCM0483 | CL89 | HEK-293T | C55(0.92) | LDD1686 | [25] |
LDCM0484 | CL9 | PaTu 8988t | C82(0.56) | LDD1363 | [11] |
LDCM0488 | CL93 | HEK-293T | C55(1.12) | LDD1691 | [25] |
LDCM0033 | Curcusone1d | MCF-7 | 2.25 | LDD0188 | [8] |
LDCM0213 | Electrophilic fragment 2 | MDA-MB-231 | C32(2.02) | LDD1702 | [7] |
LDCM0468 | Fragment33 | HCT 116 | C82(0.87) | LDD0785 | [11] |
LDCM0427 | Fragment51 | HCT 116 | C82(1.27) | LDD0744 | [11] |
LDCM0107 | IAA | HeLa | N.A. | LDD0221 | [18] |
LDCM0022 | KB02 | HCT 116 | C82(1.12) | LDD0080 | [11] |
LDCM0023 | KB03 | HCT 116 | C82(1.44) | LDD0081 | [11] |
LDCM0024 | KB05 | HCT 116 | C82(1.25) | LDD0082 | [11] |
LDCM0509 | N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide | MDA-MB-231 | C32(0.90) | LDD2102 | [7] |
LDCM0109 | NEM | HeLa | N.A. | LDD0223 | [18] |
LDCM0496 | Nucleophilic fragment 11a | MDA-MB-231 | C32(0.55) | LDD2089 | [7] |
LDCM0497 | Nucleophilic fragment 11b | MDA-MB-231 | C32(1.65) | LDD2090 | [7] |
LDCM0499 | Nucleophilic fragment 12b | MDA-MB-231 | C32(0.98) | LDD2092 | [7] |
LDCM0504 | Nucleophilic fragment 15a | MDA-MB-231 | C32(0.79); C55(1.00) | LDD2097 | [7] |
LDCM0505 | Nucleophilic fragment 15b | MDA-MB-231 | C32(0.86) | LDD2098 | [7] |
LDCM0506 | Nucleophilic fragment 16a | MDA-MB-231 | C82(1.31); C32(0.81); C55(1.24) | LDD2099 | [7] |
LDCM0507 | Nucleophilic fragment 16b | MDA-MB-231 | C32(0.44); C55(0.52) | LDD2100 | [7] |
LDCM0508 | Nucleophilic fragment 17a | MDA-MB-231 | C55(0.99) | LDD2101 | [7] |
LDCM0511 | Nucleophilic fragment 18b | MDA-MB-231 | C32(0.75) | LDD2104 | [7] |
LDCM0512 | Nucleophilic fragment 19a | MDA-MB-231 | C32(1.32) | LDD2105 | [7] |
LDCM0514 | Nucleophilic fragment 20a | MDA-MB-231 | C82(1.00); C32(0.70); C55(1.04) | LDD2107 | [7] |
LDCM0515 | Nucleophilic fragment 20b | MDA-MB-231 | C55(0.47) | LDD2108 | [7] |
LDCM0516 | Nucleophilic fragment 21a | MDA-MB-231 | C82(0.46); C32(0.70) | LDD2109 | [7] |
LDCM0517 | Nucleophilic fragment 21b | MDA-MB-231 | C55(0.86) | LDD2110 | [7] |
LDCM0518 | Nucleophilic fragment 22a | MDA-MB-231 | C82(1.03); C32(0.86) | LDD2111 | [7] |
LDCM0522 | Nucleophilic fragment 24a | MDA-MB-231 | C32(0.65) | LDD2115 | [7] |
LDCM0525 | Nucleophilic fragment 25b | MDA-MB-231 | C32(0.55) | LDD2118 | [7] |
LDCM0526 | Nucleophilic fragment 26a | MDA-MB-231 | C82(1.50); C32(2.49) | LDD2119 | [7] |
LDCM0527 | Nucleophilic fragment 26b | MDA-MB-231 | C32(1.01) | LDD2120 | [7] |
LDCM0530 | Nucleophilic fragment 28a | MDA-MB-231 | C82(1.01); C32(0.76) | LDD2123 | [7] |
LDCM0531 | Nucleophilic fragment 28b | MDA-MB-231 | C32(0.49) | LDD2124 | [7] |
LDCM0532 | Nucleophilic fragment 29a | MDA-MB-231 | C82(0.77); C32(0.66) | LDD2125 | [7] |
LDCM0533 | Nucleophilic fragment 29b | MDA-MB-231 | C32(0.35) | LDD2126 | [7] |
LDCM0534 | Nucleophilic fragment 30a | MDA-MB-231 | C32(0.66) | LDD2127 | [7] |
LDCM0535 | Nucleophilic fragment 30b | MDA-MB-231 | C32(1.00) | LDD2128 | [7] |
LDCM0536 | Nucleophilic fragment 31 | MDA-MB-231 | C82(1.62); C32(0.97) | LDD2129 | [7] |
LDCM0540 | Nucleophilic fragment 35 | MDA-MB-231 | C32(0.68); C55(0.61) | LDD2133 | [7] |
LDCM0542 | Nucleophilic fragment 37 | MDA-MB-231 | C82(1.38); C32(1.10) | LDD2135 | [7] |
LDCM0543 | Nucleophilic fragment 38 | MDA-MB-231 | C82(1.21); C32(0.77); C55(0.95) | LDD2136 | [7] |
LDCM0544 | Nucleophilic fragment 39 | MDA-MB-231 | C82(0.83); C32(0.80); C55(1.04) | LDD2137 | [7] |
LDCM0211 | Nucleophilic fragment 3b | MDA-MB-231 | C32(1.55); C82(1.15) | LDD1700 | [7] |
LDCM0546 | Nucleophilic fragment 40 | MDA-MB-231 | C82(0.93); C32(0.58); C55(1.05) | LDD2140 | [7] |
LDCM0547 | Nucleophilic fragment 41 | MDA-MB-231 | C32(0.51); C55(1.01) | LDD2141 | [7] |
LDCM0549 | Nucleophilic fragment 43 | MDA-MB-231 | C32(1.05) | LDD2143 | [7] |
LDCM0550 | Nucleophilic fragment 5a | MDA-MB-231 | C82(1.99); C32(3.38) | LDD2144 | [7] |
LDCM0551 | Nucleophilic fragment 5b | MDA-MB-231 | C32(0.71); C55(0.30) | LDD2145 | [7] |
LDCM0552 | Nucleophilic fragment 6a | MDA-MB-231 | C82(1.04); C32(0.85) | LDD2146 | [7] |
LDCM0553 | Nucleophilic fragment 6b | MDA-MB-231 | C32(3.81) | LDD2147 | [7] |
LDCM0554 | Nucleophilic fragment 7a | MDA-MB-231 | C32(0.63); C55(0.68) | LDD2148 | [7] |
LDCM0556 | Nucleophilic fragment 8a | MDA-MB-231 | C55(0.64) | LDD2150 | [7] |
LDCM0014 | Panhematin | HEK-293T | 4.33 | LDD0062 | [9] |
LDCM0131 | RA190 | MM1.R | 2.51 | LDD0300 | [10] |
References