Details of the Probe

General Information of Probe

Probe ID
LDPC0399
Probe Name
C159
Synonyms
Z3410164786
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 358.4
Lipid-water partition coefficient (xlogp) 3.5
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C21H18N4O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[2-(3-cyanophenoxy)phenyl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC2=CC=CC=C2OC3=CC=CC(=C3)C#N
InChI
InChI=1S/C21H18N4O2/c1-2-3-12-21(24-25-21)13-11-20(26)23-18-9-4-5-10-19(18)27-17-8-6-7-16(14-17)15-22/h1,4-10,14H,3,11-13H2,(H,23,26)
InChIKey
KACWCQZQAFKALR-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

148 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 10.27  LDD1839 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 11.63  LDD1839 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 16.00  LDD1839 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 9.78  LDD1839 
Acid ceramidase (ASAH1) LDTP05905 23.92  LDD1839 
Adenosine deaminase (ADA) LDTP01803 25.46  LDD1839 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 15.35  LDD1839 
ADP-dependent glucokinase (ADPGK) LDTP11127 17.15  LDD1839 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 7.31  LDD1839 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 16.34  LDD1839 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 8.40  LDD1839 
Alpha-galactosidase A (GLA) LDTP02141 7.16  LDD1839 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 10.63  LDD1839 
Antigen peptide transporter 1 (TAP1) LDTP05408 8.34  LDD1839 
Antigen peptide transporter 2 (TAP2) LDTP05409 22.78  LDD1839 
Atlastin-2 (ATL2) LDTP09251 7.26  LDD1839 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 10.20  LDD1839 
Beta-galactosidase (GLB1) LDTP02837 9.85  LDD1839 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 9.99  LDD1839 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 15.35  LDD1839 
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) LDTP00462 7.31  LDD1839 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 24.76  LDD1839 
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) LDTP05920 12.21  LDD1839 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 14.52  LDD1839 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 7.21  LDD1839 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 20.53  LDD1839 
Catechol O-methyltransferase (COMT) LDTP03145 8.22  LDD1839 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 12.82  LDD1839 
Ceramide glucosyltransferase (UGCG) LDTP06617 10.70  LDD1839 
Ceramide kinase (CERK) LDTP09391 18.38  LDD1839 
Ceramide synthase 1 (CERS1) LDTP03394 17.39  LDD1839 
Ceramide synthase 2 (CERS2) LDTP10329 11.08  LDD1839 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 10.48  LDD1839 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 10.06  LDD1839 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 23.75  LDD1839 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 22.63  LDD1839 
Cytochrome b5 type B (CYB5B) LDTP00697 74.54  LDD1839 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 13.18  LDD1839 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 15.03  LDD1839 
DCN1-like protein 4 (DCUN1D4) LDTP09799 24.93  LDD1839 
DCN1-like protein 5 (DCUN1D5) LDTP11199 54.95  LDD1839 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 10.48  LDD1839 
Delta(24)-sterol reductase (DHCR24) LDTP06375 18.64  LDD1839 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 9.38  LDD1839 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 8.17  LDD1839 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 10.13  LDD1839 
Dihydrofolate reductase (DHFR) LDTP01769 24.25  LDD1839 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 8.69  LDD1839 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 11.47  LDD1839 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 11.24  LDD1839 
E3 ubiquitin-protein ligase NEDD4 (NEDD4) LDTP04114 11.08  LDD1839 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 9.92  LDD1839 
E3 ubiquitin-protein ligase RNF13 (RNF13) LDTP00804 10.27  LDD1839 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 17.27  LDD1839 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 8.46  LDD1839 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 13.45  LDD1839 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 16.45  LDD1839 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 16.45  LDD1839 
Epoxide hydrolase 1 (EPHX1) LDTP02175 12.47  LDD1839 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 19.70  LDD1839 
Ferrochelatase, mitochondrial (FECH) LDTP03198 18.25  LDD1839 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 29.86  LDD1839 
Heme oxygenase 1 (HMOX1) LDTP02359 45.57  LDD1839 
Heme oxygenase 2 (HMOX2) LDTP03540 45.89  LDD1839 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 12.47  LDD1839 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 17.63  LDD1839 
Ketosamine-3-kinase (FN3KRP) LDTP16025 8.69  LDD1839 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 8.11  LDD1839 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 15.67  LDD1839 
Lathosterol oxidase (SC5D) LDTP01329 7.31  LDD1839 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 16.68  LDD1839 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 21.56  LDD1839 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 11.96  LDD1839 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 7.84  LDD1839 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 8.06  LDD1839 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 7.89  LDD1839 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 16.22  LDD1839 
Lysosomal alpha-glucosidase (GAA) LDTP02486 9.06  LDD1839 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 15.03  LDD1839 
Lysosomal protective protein (CTSA) LDTP02505 25.46  LDD1839 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 13.83  LDD1839 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 15.35  LDD1839 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 17.39  LDD1839 
Minor histocompatibility antigen H13 (HM13) LDTP09396 10.78  LDD1839 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 19.43  LDD1839 
N-acetylgalactosamine-6-sulfatase (GALNS) LDTP03683 8.63  LDD1839 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 11.08  LDD1839 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 13.64  LDD1839 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 9.45  LDD1839 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 8.17  LDD1839 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 39.12  LDD1839 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 15.89  LDD1839 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 8.28  LDD1839 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 15.45  LDD1839 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 8.63  LDD1839 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 31.78  LDD1839 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 7.21  LDD1839 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 8.51  LDD1839 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 11.71  LDD1839 
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) LDTP03374 9.65  LDD1839 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 13.83  LDD1839 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 16.68  LDD1839 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 8.57  LDD1839 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 7.26  LDD1839 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 7.67  LDD1839 
Phospholipase A2 group XV (PLA2G15) LDTP09088 10.63  LDD1839 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 9.71  LDD1839 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 9.71  LDD1839 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 8.22  LDD1839 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 32.67  LDD1839 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 17.27  LDD1839 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 19.84  LDD1839 
Prolyl endopeptidase-like (PREPL) LDTP06849 7.36  LDD1839 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 7.46  LDD1839 
Prostaglandin reductase 2 (PTGR2) LDTP08979 7.46  LDD1839 
Prostaglandin reductase 3 (PTGR3) LDTP15422 17.27  LDD1839 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 12.21  LDD1839 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 9.58  LDD1839 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 9.58  LDD1839 
Protein O-GlcNAcase (OGA) LDTP00988 17.15  LDD1839 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 19.43  LDD1839 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 8.94  LDD1839 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 10.20  LDD1839 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 8.88  LDD1839 
Ras-related protein Rab-24 (RAB24) LDTP10020 10.85  LDD1839 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 10.34  LDD1839 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 24.08  LDD1839 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 8.94  LDD1839 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 7.78  LDD1839 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 7.46  LDD1839 
Serine/threonine-protein kinase VRK2 (VRK2) LDTP08378 7.21  LDD1839 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 44.94  LDD1839 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 14.12  LDD1839 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 17.15  LDD1839 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 8.34  LDD1839 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 62.25  LDD1839 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 9.32  LDD1839 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 8.63  LDD1839 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 8.51  LDD1839 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 8.69  LDD1839 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 28.25  LDD1839 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 16.34  LDD1839 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 16.91  LDD1839 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 19.97  LDD1839 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 7.16  LDD1839 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 10.20  LDD1839 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 15.35  LDD1839 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 10.48  LDD1839 
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⏷ Show the Full List of 148 Enzyme
98 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 16.68  LDD1839 
Amyloid-beta precursor protein (APP) LDTP02071 10.78  LDD1839 
Anoctamin-10 (ANO10) LDTP12704 8.69  LDD1839 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 9.92  LDD1839 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 25.99  LDD1839 
BRI3-binding protein (BRI3BP) LDTP15648 9.99  LDD1839 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 8.00  LDD1839 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 20.11  LDD1839 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 8.34  LDD1839 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 20.53  LDD1839 
Derlin-1 (DERL1) LDTP11245 10.70  LDD1839 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 7.94  LDD1839 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 49.87  LDD1839 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 19.70  LDD1839 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 9.85  LDD1839 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 9.00  LDD1839 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 9.32  LDD1839 
Integral membrane protein 2B (ITM2B) LDTP13833 12.21  LDD1839 
Integral membrane protein 2C (ITM2C) LDTP12451 9.99  LDD1839 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 7.41  LDD1839 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 11.16  LDD1839 
Lysosome membrane protein 2 (SCARB2) LDTP06034 39.40  LDD1839 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 15.14  LDD1839 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 10.06  LDD1839 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 22.47  LDD1839 
Metal transporter CNNM3 (CNNM3) LDTP09144 7.41  LDD1839 
Metaxin-1 (MTX1) LDTP05900 8.00  LDD1839 
Metaxin-2 (MTX2) LDTP01217 8.82  LDD1839 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 7.46  LDD1839 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 8.51  LDD1839 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 8.46  LDD1839 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 20.39  LDD1839 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 14.72  LDD1839 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1839 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1839 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 9.58  LDD1839 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 10.85  LDD1839 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 9.92  LDD1839 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 39.40  LDD1839 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 7.84  LDD1839 
Mitoguardin 1 (MIGA1) LDTP09028 7.31  LDD1839 
Mpv17-like protein 2 (MPV17L2) LDTP14952 28.25  LDD1839 
Nucleoporin NDC1 (NDC1) LDTP11213 11.47  LDD1839 
Nucleoporin NUP35 (NUP35) LDTP09204 7.94  LDD1839 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 9.38  LDD1839 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 7.67  LDD1839 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 7.84  LDD1839 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 9.92  LDD1839 
Prosaposin (PSAP) LDTP02215 14.62  LDD1839 
Protein FAM8A1 (FAM8A1) LDTP16190 10.63  LDD1839 
Protein GPR107 (GPR107) LDTP07236 34.78  LDD1839 
Protein GPR108 (GPR108) LDTP12383 22.47  LDD1839 
Protein spinster homolog 1 (SPNS1) LDTP11844 14.42  LDD1839 
Protein tweety homolog 3 (TTYH3) LDTP11615 33.82  LDD1839 
Protein wntless homolog (WLS) LDTP07156 9.58  LDD1839 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 9.25  LDD1839 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 10.63  LDD1839 
Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) LDTP07610 8.57  LDD1839 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 13.45  LDD1839 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 13.36  LDD1839 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 7.62  LDD1839 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 19.70  LDD1839 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 9.65  LDD1839 
Sideroflexin-4 (SFXN4) LDTP07531 15.89  LDD1839 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 17.39  LDD1839 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 8.40  LDD1839 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 9.00  LDD1839 
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 8.63  LDD1839 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 22.94  LDD1839 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 10.34  LDD1839 
Solute carrier family 25 member 35 (SLC25A35) LDTP17106 9.19  LDD1839 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 7.57  LDD1839 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 11.55  LDD1839 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 18.90  LDD1839 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 24.08  LDD1839 
Sugar transporter SWEET1 (SLC50A1) LDTP11136 23.92  LDD1839 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 8.17  LDD1839 
T-complex protein 1 subunit delta (CCT4) LDTP04391 7.52  LDD1839 
Tetraspanin-3 (TSPAN3) LDTP16813 31.12  LDD1839 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 20.25  LDD1839 
Translocation protein SEC62 (SEC62) LDTP15838 7.57  LDD1839 
Translocator protein (TSPO) LDTP03546 19.16  LDD1839 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 34.30  LDD1839 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 17.03  LDD1839 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 10.93  LDD1839 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 40.50  LDD1839 
Transmembrane protein 126A (TMEM126A) LDTP15948 23.75  LDD1839 
Transmembrane protein 199 (TMEM199) LDTP08881 27.67  LDD1839 
Transmembrane protein 230 (TMEM230) LDTP10065 13.55  LDD1839 
Transmembrane protein 245 (TMEM245) LDTP15979 9.85  LDD1839 
Transmembrane protein 33 (TMEM33) LDTP04787 7.41  LDD1839 
Transmembrane protein 59 (TMEM59) LDTP11406 32.67  LDD1839 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 16.80  LDD1839 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 8.28  LDD1839 
Vang-like protein 1 (VANGL1) LDTP09288 9.19  LDD1839 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 40.79  LDD1839 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 35.51  LDD1839 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 9.71  LDD1839 
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⏷ Show the Full List of 98 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 10.70  LDD1839 
Glucocorticoid receptor (NR3C1) LDTP02016 8.11  LDD1839 
Protein Wiz (WIZ) LDTP01674 9.32  LDD1839 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Coxsackievirus and adenovirus receptor (CXADR) LDTP05085 8.40  LDD1839 
Leukocyte surface antigen CD47 (CD47) LDTP05572 8.94  LDD1839 
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92 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 10.93  LDD1839 
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (ACAP2) LDTP06302 12.04  LDD1839 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 8.69  LDD1839 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 16.22  LDD1839 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 7.89  LDD1839 
Centrin-2 (CETN2) LDTP03926 7.52  LDD1839 
Centromere protein K (CENPK) LDTP11143 9.13  LDD1839 
Clustered mitochondria protein homolog (CLUH) LDTP14486 11.24  LDD1839 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 7.21  LDD1839 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 45.57  LDD1839 
Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) LDTP10281 7.73  LDD1839 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 7.21  LDD1839 
Desmocollin-3 (DSC3) LDTP06154 7.84  LDD1839 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 9.25  LDD1839 
Dynactin subunit 3 (DCTN3) LDTP01359 7.26  LDD1839 
Dynactin subunit 4 (DCTN4) LDTP13402 7.16  LDD1839 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 17.03  LDD1839 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 9.65  LDD1839 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 11.47  LDD1839 
Emerin (EMD) LDTP04356 7.94  LDD1839 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 28.05  LDD1839 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1839 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 14.22  LDD1839 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 7.57  LDD1839 
Galectin-3-binding protein (LGALS3BP) LDTP05558 7.62  LDD1839 
Ganglioside GM2 activator (GM2A) LDTP02927 10.48  LDD1839 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 16.34  LDD1839 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 8.88  LDD1839 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 8.22  LDD1839 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 7.89  LDD1839 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 11.31  LDD1839 
Kinetochore protein Spc24 (SPC24) LDTP09069 10.85  LDD1839 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 10.13  LDD1839 
Large proline-rich protein BAG6 (BAG6) LDTP04094 12.47  LDD1839 
Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1) LDTP13210 10.20  LDD1839 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 23.43  LDD1839 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 12.21  LDD1839 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 8.69  LDD1839 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 17.75  LDD1839 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 8.22  LDD1839 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 66.72  LDD1839 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 25.63  LDD1839 
Neurofilament medium polypeptide (NEFM) LDTP02181 7.73  LDD1839 
Nicastrin (NCSTN) LDTP09787 7.21  LDD1839 
Nuclear inhibitor of protein phosphatase 1 (PPP1R8) LDTP05711 9.71  LDD1839 
Nucleobindin-1 (NUCB1) LDTP05375 25.63  LDD1839 
Nucleobindin-2 (NUCB2) LDTP05160 21.26  LDD1839 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 8.40  LDD1839 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.06  LDD1839 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 9.13  LDD1839 
Optic atrophy 3 protein (OPA3) LDTP16006 16.34  LDD1839 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 16.80  LDD1839 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 9.51  LDD1839 
Protein CEBPZOS (CEBPZOS) LDTP18883 29.04  LDD1839 
Protein FAM114A2 (FAM114A2) LDTP16080 11.08  LDD1839 
Protein FAM162A (FAM162A) LDTP10056 10.78  LDD1839 
Protein FAM3C (FAM3C) LDTP09773 7.62  LDD1839 
Protein jagunal homolog 1 (JAGN1) LDTP08904 9.06  LDD1839 
Protein kish-B (TMEM167B) LDTP12545 8.06  LDD1839 
Protein LYRIC (MTDH) LDTP08224 9.65  LDD1839 
Protein unc-119 homolog A (UNC119) LDTP05868 14.83  LDD1839 
Protein unc-119 homolog B (UNC119B) LDTP00105 15.78  LDD1839 
Protein YIF1A (YIF1A) LDTP01494 10.27  LDD1839 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 9.06  LDD1839 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 10.70  LDD1839 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 7.52  LDD1839 
Reticulocalbin-2 (RCN2) LDTP06097 9.19  LDD1839 
Reticulon-2 (RTN2) LDTP01167 10.70  LDD1839 
Reticulon-3 (RTN3) LDTP01522 22.63  LDD1839 
Reticulon-4 (RTN4) LDTP12412 19.56  LDD1839 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 16.68  LDD1839 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 9.13  LDD1839 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 8.46  LDD1839 
Synaptogyrin-2 (SYNGR2) LDTP00859 14.52  LDD1839 
Syntaxin-10 (STX10) LDTP00986 21.11  LDD1839 
Syntaxin-18 (STX18) LDTP13086 22.01  LDD1839 
Tetraspanin-6 (TSPAN6) LDTP14458 29.86  LDD1839 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 8.88  LDD1839 
Tetratricopeptide repeat protein 39C (TTC39C) LDTP17713 7.73  LDD1839 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 9.32  LDD1839 
TraB domain-containing protein (TRABD) LDTP19963 11.55  LDD1839 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 10.34  LDD1839 
Transmembrane protein 209 (TMEM209) LDTP18272 9.06  LDD1839 
Trophoblast glycoprotein (TPBG) LDTP05960 8.82  LDD1839 
Tubulin beta chain (TUBB) LDTP02205 25.63  LDD1839 
Tubulin beta-2B chain (TUBB2B) LDTP11277 29.65  LDD1839 
Tubulin beta-4A chain (TUBB4A) LDTP02037 23.75  LDD1839 
Tubulin beta-6 chain (TUBB6) LDTP11233 16.22  LDD1839 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 38.59  LDD1839 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 10.06  LDD1839 
Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) LDTP06808 7.67  LDD1839 
Wings apart-like protein homolog (WAPL) LDTP08094 7.21  LDD1839 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1839 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587