Details of the Target

General Information of Target

Target ID	LDTP19963
Target Name	TraB domain-containing protein (TRABD)
Gene Name	TRABD
Gene ID	80305
Synonyms	TTG2; TraB domain-containing protein; Protein TTG2
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MAVFHDEVEIEDFQYDEDSETYFCPCPCGDNFSITKEELENGEGVAMCPGCSLIIKVIYD KDQFACGETVPVPSVNKE
Target Bioclass	Other
Uniprot ID	Q9H4I3
Ensemble ID	ENST00000303434.8
HGNC ID	HGNC:28805

Target Site Mutations in Different Cell Lines

Cell line	Mutation details	Probe for labeling this protein in this cell
MFE296	SNV: p.Q7H	DBIA Probe Info
NCIH1155	SNV: p.A69V	.
REC1	SNV: p.R111C	DBIA Probe Info
SNU1	SNV: p.L129F	DBIA Probe Info

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 18 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
m-APA Probe Info	15.00	LDD0402	[1]
HDSF-alk Probe Info	2.37	LDD0197	[2]
TG42 Probe Info	4.61	LDD0326	[3]
YN-4 Probe Info	100.00	LDD0445	[4]
Curcusone 37 Probe Info	2.07	LDD0188	[5]
Jackson_1 Probe Info	2.39	LDD0120	[6]
AHL-Pu-1 Probe Info	C287(2.07)	LDD0169	[7]
HPAP Probe Info	5.52	LDD0062	[8]
DBIA Probe Info	C287(2.77)	LDD0080	[9]
4-Iodoacetamidophenylacetylene Probe Info	N.A.	LDD0038	[10]
IA-alkyne Probe Info	C108(0.00); C217(0.00)	LDD0036	[10]
Lodoacetamide azide Probe Info	C217(0.00); C108(0.00)	LDD0037	[10]
JW-RF-010 Probe Info	C108(0.00); C366(0.00)	LDD0026	[11]
TFBX Probe Info	C108(0.00); C366(0.00)	LDD0027	[11]
Compound 10 Probe Info	N.A.	LDD2216	[12]
IPM Probe Info	N.A.	LDD0005	[13]
AOyne Probe Info	15.00	LDD0443	[14]
NAIA_5 Probe Info	C184(0.00); C287(0.00)	LDD2223	[15]

PAL-AfBPP Probe

Click To Hide/Show 126 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
C004 Probe Info	10.27	LDD1714	[16]
C022 Probe Info	15.67	LDD1728	[16]
C027 Probe Info	7.16	LDD1733	[16]
C040 Probe Info	12.13	LDD1740	[16]
C041 Probe Info	10.13	LDD1741	[16]
C053 Probe Info	5.50	LDD1751	[16]
C055 Probe Info	16.34	LDD1752	[16]
C056 Probe Info	34.54	LDD1753	[16]
C063 Probe Info	11.96	LDD1760	[16]
C070 Probe Info	14.03	LDD1766	[16]
C072 Probe Info	8.06	LDD1768	[16]
C082 Probe Info	6.87	LDD1774	[16]
C087 Probe Info	12.47	LDD1779	[16]
C091 Probe Info	21.41	LDD1782	[16]
C092 Probe Info	36.00	LDD1783	[16]
C094 Probe Info	64.89	LDD1785	[16]
C100 Probe Info	7.41	LDD1789	[16]
C106 Probe Info	43.11	LDD1793	[16]
C107 Probe Info	7.46	LDD1794	[16]
C108 Probe Info	12.30	LDD1795	[16]
C112 Probe Info	31.78	LDD1799	[16]
C130 Probe Info	7.41	LDD1812	[16]
C134 Probe Info	39.95	LDD1816	[16]
C135 Probe Info	17.27	LDD1817	[16]
C139 Probe Info	10.34	LDD1821	[16]
C141 Probe Info	14.62	LDD1823	[16]
C143 Probe Info	21.71	LDD1825	[16]
C153 Probe Info	32.67	LDD1834	[16]
C158 Probe Info	11.16	LDD1838	[16]
C159 Probe Info	11.55	LDD1839	[16]
C160 Probe Info	9.45	LDD1840	[16]
C161 Probe Info	19.56	LDD1841	[16]
C163 Probe Info	7.84	LDD1843	[16]
C166 Probe Info	7.11	LDD1846	[16]
C169 Probe Info	29.24	LDD1849	[16]
C177 Probe Info	7.41	LDD1856	[16]
C178 Probe Info	24.42	LDD1857	[16]
C186 Probe Info	8.57	LDD1864	[16]
C187 Probe Info	16.56	LDD1865	[16]
C194 Probe Info	15.03	LDD1870	[16]
C196 Probe Info	13.74	LDD1872	[16]
C198 Probe Info	14.72	LDD1874	[16]
C201 Probe Info	44.63	LDD1877	[16]
C206 Probe Info	25.46	LDD1881	[16]
C210 Probe Info	71.51	LDD1884	[16]
C215 Probe Info	5.98	LDD1889	[16]
C218 Probe Info	45.57	LDD1892	[16]
C219 Probe Info	6.96	LDD1893	[16]
C220 Probe Info	23.10	LDD1894	[16]
C225 Probe Info	5.94	LDD1898	[16]
C226 Probe Info	6.11	LDD1899	[16]
C228 Probe Info	30.27	LDD1901	[16]
C229 Probe Info	7.94	LDD1902	[16]
C231 Probe Info	32.45	LDD1904	[16]
C232 Probe Info	68.59	LDD1905	[16]
C233 Probe Info	12.47	LDD1906	[16]
C234 Probe Info	8.06	LDD1907	[16]
C235 Probe Info	42.81	LDD1908	[16]
C238 Probe Info	19.43	LDD1911	[16]
C243 Probe Info	16.56	LDD1916	[16]
C244 Probe Info	18.00	LDD1917	[16]
C246 Probe Info	22.32	LDD1919	[16]
C249 Probe Info	14.52	LDD1922	[16]
C251 Probe Info	38.59	LDD1924	[16]
C252 Probe Info	15.45	LDD1925	[16]
C264 Probe Info	24.25	LDD1935	[16]
C265 Probe Info	20.53	LDD1936	[16]
C269 Probe Info	5.86	LDD1939	[16]
C273 Probe Info	5.17	LDD1943	[16]
C275 Probe Info	5.86	LDD1945	[16]
C277 Probe Info	14.03	LDD1947	[16]
C278 Probe Info	87.43	LDD1948	[16]
C282 Probe Info	21.56	LDD1952	[16]
C284 Probe Info	28.64	LDD1954	[16]
C285 Probe Info	34.06	LDD1955	[16]
C287 Probe Info	12.82	LDD1957	[16]
C288 Probe Info	8.17	LDD1958	[16]
C289 Probe Info	60.13	LDD1959	[16]
C293 Probe Info	36.50	LDD1963	[16]
C296 Probe Info	25.63	LDD1966	[16]
C299 Probe Info	13.83	LDD1968	[16]
C305 Probe Info	10.70	LDD1974	[16]
C310 Probe Info	10.13	LDD1977	[16]
C313 Probe Info	12.30	LDD1980	[16]
C314 Probe Info	14.72	LDD1981	[16]
C322 Probe Info	10.34	LDD1988	[16]
C338 Probe Info	12.04	LDD2001	[16]
C339 Probe Info	9.13	LDD2002	[16]
C343 Probe Info	27.67	LDD2005	[16]
C348 Probe Info	16.11	LDD2009	[16]
C349 Probe Info	24.42	LDD2010	[16]
C350 Probe Info	69.07	LDD2011	[16]
C355 Probe Info	48.50	LDD2016	[16]
C356 Probe Info	14.72	LDD2017	[16]
C357 Probe Info	6.92	LDD2018	[16]
C361 Probe Info	24.08	LDD2022	[16]
C362 Probe Info	99.73	LDD2023	[16]
C363 Probe Info	26.72	LDD2024	[16]
C364 Probe Info	29.65	LDD2025	[16]
C366 Probe Info	11.79	LDD2027	[16]
C367 Probe Info	8.06	LDD2028	[16]
C373 Probe Info	9.78	LDD2033	[16]
C376 Probe Info	12.64	LDD2036	[16]
C382 Probe Info	12.82	LDD2041	[16]
C383 Probe Info	15.35	LDD2042	[16]
C386 Probe Info	6.82	LDD2045	[16]
C388 Probe Info	97.01	LDD2047	[16]
C390 Probe Info	51.63	LDD2049	[16]
C391 Probe Info	19.43	LDD2050	[16]
C399 Probe Info	9.19	LDD2058	[16]
C403 Probe Info	39.67	LDD2061	[16]
C407 Probe Info	34.54	LDD2064	[16]
C413 Probe Info	12.30	LDD2069	[16]
C424 Probe Info	8.46	LDD2079	[16]
C426 Probe Info	21.71	LDD2081	[16]
C429 Probe Info	13.55	LDD2084	[16]
C430 Probe Info	4.96	LDD2085	[16]
C431 Probe Info	19.70	LDD2086	[16]
C433 Probe Info	8.82	LDD2088	[16]
FFF probe11 Probe Info	20.00	LDD0471	[17]
FFF probe13 Probe Info	19.39	LDD0475	[17]
FFF probe14 Probe Info	20.00	LDD0477	[17]
FFF probe2 Probe Info	20.00	LDD0463	[17]
FFF probe3 Probe Info	20.00	LDD0464	[17]
VE-P Probe Info	N.A.	LDD0396	[18]
OEA-DA Probe Info	13.68	LDD0046	[19]

Competitor(s) Related to This Target

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0025	4SU-RNA	DM93	C184(2.45)	LDD0170	[7]
LDCM0026	4SU-RNA+native RNA	HEK-293T	C287(2.07)	LDD0169	[7]
LDCM0214	AC1	HCT 116	C108(1.08); C287(0.83)	LDD0531	[9]
LDCM0215	AC10	HCT 116	C108(0.76); C217(0.87); C287(1.07)	LDD0532	[9]
LDCM0216	AC100	HCT 116	C108(0.60)	LDD0533	[9]
LDCM0217	AC101	HCT 116	C108(0.67)	LDD0534	[9]
LDCM0218	AC102	HCT 116	C108(0.95)	LDD0535	[9]
LDCM0219	AC103	HCT 116	C108(0.98)	LDD0536	[9]
LDCM0220	AC104	HCT 116	C108(0.67)	LDD0537	[9]
LDCM0221	AC105	HCT 116	C108(0.75)	LDD0538	[9]
LDCM0222	AC106	HCT 116	C108(0.89)	LDD0539	[9]
LDCM0223	AC107	HCT 116	C108(0.99)	LDD0540	[9]
LDCM0224	AC108	HCT 116	C108(0.56)	LDD0541	[9]
LDCM0225	AC109	HCT 116	C108(0.66)	LDD0542	[9]
LDCM0226	AC11	HCT 116	C108(0.71); C217(0.87); C287(1.34)	LDD0543	[9]
LDCM0227	AC110	HCT 116	C108(0.62)	LDD0544	[9]
LDCM0228	AC111	HCT 116	C108(0.59)	LDD0545	[9]
LDCM0229	AC112	HCT 116	C108(0.58)	LDD0546	[9]
LDCM0230	AC113	PaTu 8988t	C217(1.11)	LDD1109	[9]
LDCM0231	AC114	PaTu 8988t	C217(0.97)	LDD1110	[9]
LDCM0232	AC115	PaTu 8988t	C217(1.01)	LDD1111	[9]
LDCM0233	AC116	PaTu 8988t	C217(1.13)	LDD1112	[9]
LDCM0234	AC117	PaTu 8988t	C217(0.83)	LDD1113	[9]
LDCM0235	AC118	PaTu 8988t	C217(0.93)	LDD1114	[9]
LDCM0236	AC119	PaTu 8988t	C217(1.07)	LDD1115	[9]
LDCM0237	AC12	HCT 116	C108(0.72); C217(0.87); C287(1.13)	LDD0554	[9]
LDCM0238	AC120	PaTu 8988t	C217(1.47)	LDD1117	[9]
LDCM0239	AC121	PaTu 8988t	C217(1.13)	LDD1118	[9]
LDCM0240	AC122	PaTu 8988t	C217(1.59)	LDD1119	[9]
LDCM0241	AC123	PaTu 8988t	C217(1.65)	LDD1120	[9]
LDCM0242	AC124	PaTu 8988t	C217(1.33)	LDD1121	[9]
LDCM0243	AC125	PaTu 8988t	C217(1.13)	LDD1122	[9]
LDCM0244	AC126	PaTu 8988t	C217(1.18)	LDD1123	[9]
LDCM0245	AC127	PaTu 8988t	C217(1.40)	LDD1124	[9]
LDCM0246	AC128	HCT 116	C108(0.91)	LDD0563	[9]
LDCM0247	AC129	HCT 116	C108(0.82)	LDD0564	[9]
LDCM0249	AC130	HCT 116	C108(1.07)	LDD0566	[9]
LDCM0250	AC131	HCT 116	C108(1.21)	LDD0567	[9]
LDCM0251	AC132	HCT 116	C108(1.49)	LDD0568	[9]
LDCM0252	AC133	HCT 116	C108(1.01)	LDD0569	[9]
LDCM0253	AC134	HCT 116	C108(0.87)	LDD0570	[9]
LDCM0254	AC135	HCT 116	C108(1.16)	LDD0571	[9]
LDCM0255	AC136	HCT 116	C108(1.30)	LDD0572	[9]
LDCM0256	AC137	HCT 116	C108(0.68)	LDD0573	[9]
LDCM0257	AC138	HCT 116	C108(0.65)	LDD0574	[9]
LDCM0258	AC139	HCT 116	C108(1.75)	LDD0575	[9]
LDCM0259	AC14	HCT 116	C108(0.78); C217(0.89); C287(1.25)	LDD0576	[9]
LDCM0260	AC140	HCT 116	C108(1.29)	LDD0577	[9]
LDCM0261	AC141	HCT 116	C108(1.04)	LDD0578	[9]
LDCM0262	AC142	HCT 116	C108(1.01)	LDD0579	[9]
LDCM0263	AC143	HCT 116	C217(0.82); C108(0.94)	LDD0580	[9]
LDCM0264	AC144	HCT 116	C108(0.89); C217(0.93)	LDD0581	[9]
LDCM0265	AC145	HCT 116	C217(0.90); C108(1.05)	LDD0582	[9]
LDCM0266	AC146	HCT 116	C217(0.91); C108(1.04)	LDD0583	[9]
LDCM0267	AC147	HCT 116	C108(0.86); C217(1.11)	LDD0584	[9]
LDCM0268	AC148	HCT 116	C217(1.30); C108(1.64)	LDD0585	[9]
LDCM0269	AC149	HCT 116	C217(0.92); C108(1.28)	LDD0586	[9]
LDCM0270	AC15	HCT 116	C108(0.84); C217(0.97); C287(1.29)	LDD0587	[9]
LDCM0271	AC150	HCT 116	C108(0.93); C217(0.95)	LDD0588	[9]
LDCM0272	AC151	HCT 116	C217(0.78); C108(0.92)	LDD0589	[9]
LDCM0273	AC152	HCT 116	C217(1.08); C108(1.24)	LDD0590	[9]
LDCM0274	AC153	HCT 116	C217(1.14); C108(1.14)	LDD0591	[9]
LDCM0621	AC154	HCT 116	C108(1.11); C217(1.02)	LDD2158	[9]
LDCM0622	AC155	HCT 116	C108(1.24); C217(0.94)	LDD2159	[9]
LDCM0623	AC156	HCT 116	C108(1.31); C217(0.94)	LDD2160	[9]
LDCM0624	AC157	HCT 116	C108(1.01); C217(0.98)	LDD2161	[9]
LDCM0276	AC17	HCT 116	C217(0.87); C287(0.89); C108(1.02)	LDD0593	[9]
LDCM0277	AC18	HCT 116	C108(0.81); C217(0.88); C287(1.10)	LDD0594	[9]
LDCM0278	AC19	HCT 116	C108(0.68); C287(0.87); C217(0.93)	LDD0595	[9]
LDCM0279	AC2	HCT 116	C287(1.02); C108(1.59)	LDD0596	[9]
LDCM0280	AC20	HCT 116	C108(0.71); C217(0.81); C287(0.90)	LDD0597	[9]
LDCM0281	AC21	HCT 116	C108(0.73); C217(0.84); C287(0.89)	LDD0598	[9]
LDCM0282	AC22	HCT 116	C108(0.55); C287(0.74); C217(0.75)	LDD0599	[9]
LDCM0283	AC23	HCT 116	C108(0.61); C287(0.82); C217(0.93)	LDD0600	[9]
LDCM0284	AC24	HCT 116	C108(0.69); C287(0.85); C217(1.04)	LDD0601	[9]
LDCM0285	AC25	HCT 116	C108(0.99)	LDD0602	[9]
LDCM0286	AC26	HCT 116	C108(1.27)	LDD0603	[9]
LDCM0287	AC27	HCT 116	C108(1.25)	LDD0604	[9]
LDCM0288	AC28	HCT 116	C108(1.25)	LDD0605	[9]
LDCM0289	AC29	HCT 116	C108(1.15)	LDD0606	[9]
LDCM0290	AC3	HCT 116	C287(0.98); C108(1.44)	LDD0607	[9]
LDCM0291	AC30	HCT 116	C108(1.18)	LDD0608	[9]
LDCM0292	AC31	HCT 116	C108(1.21)	LDD0609	[9]
LDCM0293	AC32	HCT 116	C108(1.41)	LDD0610	[9]
LDCM0294	AC33	HCT 116	C108(1.24)	LDD0611	[9]
LDCM0295	AC34	HCT 116	C108(1.66)	LDD0612	[9]
LDCM0296	AC35	HCT 116	C287(0.91)	LDD0613	[9]
LDCM0297	AC36	HCT 116	C287(0.85)	LDD0614	[9]
LDCM0298	AC37	HCT 116	C287(0.88)	LDD0615	[9]
LDCM0299	AC38	HCT 116	C287(1.04)	LDD0616	[9]
LDCM0300	AC39	HCT 116	C287(1.08)	LDD0617	[9]
LDCM0301	AC4	HCT 116	C287(1.17); C108(1.41)	LDD0618	[9]
LDCM0302	AC40	HCT 116	C287(1.02)	LDD0619	[9]
LDCM0303	AC41	HCT 116	C287(1.00)	LDD0620	[9]
LDCM0304	AC42	HCT 116	C287(1.14)	LDD0621	[9]
LDCM0305	AC43	HCT 116	C287(0.97)	LDD0622	[9]
LDCM0306	AC44	HCT 116	C287(1.02)	LDD0623	[9]
LDCM0307	AC45	HCT 116	C287(1.13)	LDD0624	[9]
LDCM0308	AC46	HCT 116	C287(0.89)	LDD0625	[9]
LDCM0309	AC47	HCT 116	C287(1.02)	LDD0626	[9]
LDCM0310	AC48	HCT 116	C287(1.19)	LDD0627	[9]
LDCM0311	AC49	HCT 116	C287(1.21)	LDD0628	[9]
LDCM0312	AC5	HCT 116	C287(0.86); C108(1.59)	LDD0629	[9]
LDCM0313	AC50	HCT 116	C287(1.20)	LDD0630	[9]
LDCM0314	AC51	HCT 116	C287(0.93)	LDD0631	[9]
LDCM0315	AC52	HCT 116	C287(1.00)	LDD0632	[9]
LDCM0316	AC53	HCT 116	C287(1.26)	LDD0633	[9]
LDCM0317	AC54	HCT 116	C287(1.01)	LDD0634	[9]
LDCM0318	AC55	HCT 116	C287(1.17)	LDD0635	[9]
LDCM0319	AC56	HCT 116	C287(1.45)	LDD0636	[9]
LDCM0320	AC57	PaTu 8988t	C217(1.45)	LDD1199	[9]
LDCM0321	AC58	PaTu 8988t	C217(1.16)	LDD1200	[9]
LDCM0322	AC59	PaTu 8988t	C217(1.16)	LDD1201	[9]
LDCM0323	AC6	HCT 116	C108(0.71); C217(1.00); C287(1.14)	LDD0640	[9]
LDCM0324	AC60	PaTu 8988t	C217(1.09)	LDD1203	[9]
LDCM0325	AC61	PaTu 8988t	C217(1.06)	LDD1204	[9]
LDCM0326	AC62	PaTu 8988t	C217(1.09)	LDD1205	[9]
LDCM0327	AC63	PaTu 8988t	C217(0.97)	LDD1206	[9]
LDCM0328	AC64	PaTu 8988t	C217(1.11)	LDD1207	[9]
LDCM0329	AC65	PaTu 8988t	C217(1.24)	LDD1208	[9]
LDCM0330	AC66	PaTu 8988t	C217(1.14)	LDD1209	[9]
LDCM0331	AC67	PaTu 8988t	C217(1.00)	LDD1210	[9]
LDCM0332	AC68	HCT 116	C217(1.01)	LDD0649	[9]
LDCM0333	AC69	HCT 116	C217(0.93)	LDD0650	[9]
LDCM0334	AC7	HCT 116	C108(0.79); C217(0.99); C287(1.18)	LDD0651	[9]
LDCM0335	AC70	HCT 116	C217(0.97)	LDD0652	[9]
LDCM0336	AC71	HCT 116	C217(1.13)	LDD0653	[9]
LDCM0337	AC72	HCT 116	C217(1.13)	LDD0654	[9]
LDCM0338	AC73	HCT 116	C217(1.25)	LDD0655	[9]
LDCM0339	AC74	HCT 116	C217(1.16)	LDD0656	[9]
LDCM0340	AC75	HCT 116	C217(1.33)	LDD0657	[9]
LDCM0341	AC76	HCT 116	C217(1.08)	LDD0658	[9]
LDCM0342	AC77	HCT 116	C217(0.99)	LDD0659	[9]
LDCM0343	AC78	HCT 116	C217(0.77)	LDD0660	[9]
LDCM0344	AC79	HCT 116	C217(1.06)	LDD0661	[9]
LDCM0345	AC8	HCT 116	C217(0.95); C108(1.02); C287(1.08)	LDD0662	[9]
LDCM0346	AC80	HCT 116	C217(1.07)	LDD0663	[9]
LDCM0347	AC81	HCT 116	C217(0.42)	LDD0664	[9]
LDCM0348	AC82	HCT 116	C217(1.28)	LDD0665	[9]
LDCM0349	AC83	HEK-293T	C217(0.91)	LDD0947	[9]
LDCM0350	AC84	HEK-293T	C217(1.14)	LDD0948	[9]
LDCM0351	AC85	HEK-293T	C217(1.16)	LDD0949	[9]
LDCM0352	AC86	HEK-293T	C217(1.00)	LDD0950	[9]
LDCM0353	AC87	HEK-293T	C217(1.03)	LDD0951	[9]
LDCM0354	AC88	HEK-293T	C217(1.18)	LDD0952	[9]
LDCM0355	AC89	HEK-293T	C217(1.17)	LDD0953	[9]
LDCM0357	AC90	HEK-293T	C217(1.15)	LDD0955	[9]
LDCM0358	AC91	HEK-293T	C217(1.01)	LDD0956	[9]
LDCM0359	AC92	HEK-293T	C217(1.01)	LDD0957	[9]
LDCM0360	AC93	HEK-293T	C217(1.01)	LDD0958	[9]
LDCM0361	AC94	HEK-293T	C217(1.22)	LDD0959	[9]
LDCM0362	AC95	HEK-293T	C217(1.17)	LDD0960	[9]
LDCM0363	AC96	HEK-293T	C217(1.09)	LDD0961	[9]
LDCM0364	AC97	HEK-293T	C217(1.31)	LDD0962	[9]
LDCM0365	AC98	HCT 116	C108(0.95)	LDD0682	[9]
LDCM0366	AC99	HCT 116	C108(0.69)	LDD0683	[9]
LDCM0248	AKOS034007472	HCT 116	C108(0.78); C217(0.86); C287(1.25)	LDD0565	[9]
LDCM0356	AKOS034007680	HCT 116	C108(0.68); C217(0.88); C287(1.27)	LDD0673	[9]
LDCM0275	AKOS034007705	HCT 116	C108(0.93); C217(1.00); C287(1.94)	LDD0592	[9]
LDCM0070	Cisar_cp37	MDA-MB-231	2.39	LDD0120	[6]
LDCM0632	CL-Sc	Hep-G2	C287(0.94)	LDD2227	[15]
LDCM0367	CL1	HCT 116	C287(0.99); C217(1.00); C108(1.04)	LDD0684	[9]
LDCM0368	CL10	HCT 116	C108(0.98); C287(1.00); C217(1.11)	LDD0685	[9]
LDCM0369	CL100	HCT 116	C287(0.90); C108(1.39)	LDD0686	[9]
LDCM0370	CL101	HCT 116	C108(0.90); C217(0.98); C287(1.30)	LDD0687	[9]
LDCM0371	CL102	HCT 116	C108(0.63); C217(0.94); C287(1.03)	LDD0688	[9]
LDCM0372	CL103	HCT 116	C108(0.72); C217(0.75); C287(1.07)	LDD0689	[9]
LDCM0373	CL104	HCT 116	C108(0.66); C217(0.80); C287(1.23)	LDD0690	[9]
LDCM0374	CL105	HCT 116	C217(0.86); C108(0.89); C287(0.98)	LDD0691	[9]
LDCM0375	CL106	HCT 116	C108(0.53); C217(0.85); C287(1.13)	LDD0692	[9]
LDCM0376	CL107	HCT 116	C108(0.80); C217(0.90); C287(1.37)	LDD0693	[9]
LDCM0377	CL108	HCT 116	C108(0.83); C217(1.09); C287(1.34)	LDD0694	[9]
LDCM0378	CL109	HCT 116	C108(0.83); C217(0.93); C287(0.94)	LDD0695	[9]
LDCM0379	CL11	HCT 116	C217(0.98); C108(1.08); C287(1.09)	LDD0696	[9]
LDCM0380	CL110	HCT 116	C108(1.02); C287(1.10); C217(1.14)	LDD0697	[9]
LDCM0381	CL111	HCT 116	C108(0.68); C287(0.96); C217(1.01)	LDD0698	[9]
LDCM0382	CL112	HCT 116	C108(1.08)	LDD0699	[9]
LDCM0383	CL113	HCT 116	C108(1.27)	LDD0700	[9]
LDCM0384	CL114	HCT 116	C108(1.23)	LDD0701	[9]
LDCM0385	CL115	HCT 116	C108(1.30)	LDD0702	[9]
LDCM0386	CL116	HCT 116	C108(1.08)	LDD0703	[9]
LDCM0387	CL117	HCT 116	C287(1.40)	LDD0704	[9]
LDCM0388	CL118	HCT 116	C287(1.03)	LDD0705	[9]
LDCM0389	CL119	HCT 116	C287(1.07)	LDD0706	[9]
LDCM0390	CL12	HCT 116	C108(1.15); C287(1.15); C217(1.24)	LDD0707	[9]
LDCM0391	CL120	HCT 116	C287(1.04)	LDD0708	[9]
LDCM0392	CL121	HCT 116	C287(0.89)	LDD0709	[9]
LDCM0393	CL122	HCT 116	C287(0.88)	LDD0710	[9]
LDCM0394	CL123	HCT 116	C287(1.35)	LDD0711	[9]
LDCM0395	CL124	HCT 116	C287(1.20)	LDD0712	[9]
LDCM0396	CL125	PaTu 8988t	C217(1.04)	LDD1275	[9]
LDCM0397	CL126	PaTu 8988t	C217(1.04)	LDD1276	[9]
LDCM0398	CL127	PaTu 8988t	C217(1.27)	LDD1277	[9]
LDCM0399	CL128	PaTu 8988t	C217(1.25)	LDD1278	[9]
LDCM0400	CL13	HCT 116	C108(0.78); C217(1.01); C287(1.09)	LDD0717	[9]
LDCM0401	CL14	HCT 116	C287(1.07); C108(1.19); C217(1.20)	LDD0718	[9]
LDCM0402	CL15	HCT 116	C108(0.88); C287(1.08); C217(1.08)	LDD0719	[9]
LDCM0403	CL16	HCT 116	C287(0.95); C217(1.10); C108(1.25)	LDD0720	[9]
LDCM0404	CL17	HCT 116	C108(0.84); C217(1.00); C287(1.06)	LDD0721	[9]
LDCM0405	CL18	HCT 116	C217(0.83); C108(0.96); C287(0.98)	LDD0722	[9]
LDCM0406	CL19	HCT 116	C217(0.93); C287(1.08); C108(1.31)	LDD0723	[9]
LDCM0407	CL2	HCT 116	C217(0.95); C287(1.11); C108(1.33)	LDD0724	[9]
LDCM0408	CL20	HCT 116	C217(1.07); C287(1.08); C108(1.22)	LDD0725	[9]
LDCM0409	CL21	HCT 116	C217(1.06); C108(1.21); C287(1.28)	LDD0726	[9]
LDCM0410	CL22	HCT 116	C217(1.06); C108(1.41); C287(1.55)	LDD0727	[9]
LDCM0411	CL23	HCT 116	C108(1.06); C287(1.10); C217(1.14)	LDD0728	[9]
LDCM0412	CL24	HCT 116	C108(1.28); C217(1.11); C287(1.10)	LDD0729	[9]
LDCM0413	CL25	HCT 116	C108(1.22); C217(1.09); C287(1.21)	LDD0730	[9]
LDCM0414	CL26	HCT 116	C108(1.30); C217(1.14); C287(0.95)	LDD0731	[9]
LDCM0415	CL27	HCT 116	C108(1.03); C217(0.85); C287(1.22)	LDD0732	[9]
LDCM0416	CL28	HCT 116	C108(1.14); C217(1.02); C287(1.06)	LDD0733	[9]
LDCM0417	CL29	HCT 116	C108(1.02); C217(0.89); C287(1.03)	LDD0734	[9]
LDCM0418	CL3	HCT 116	C108(1.24); C217(1.11); C287(1.06)	LDD0735	[9]
LDCM0419	CL30	HCT 116	C108(1.00); C217(0.93); C287(0.94)	LDD0736	[9]
LDCM0420	CL31	HCT 116	C108(1.12)	LDD0737	[9]
LDCM0421	CL32	HCT 116	C108(0.61)	LDD0738	[9]
LDCM0422	CL33	HCT 116	C108(1.05)	LDD0739	[9]
LDCM0423	CL34	HCT 116	C108(0.70)	LDD0740	[9]
LDCM0424	CL35	HCT 116	C108(0.67)	LDD0741	[9]
LDCM0425	CL36	HCT 116	C108(1.18)	LDD0742	[9]
LDCM0426	CL37	HCT 116	C108(0.89)	LDD0743	[9]
LDCM0428	CL39	HCT 116	C108(0.97)	LDD0745	[9]
LDCM0429	CL4	HCT 116	C108(1.04); C217(1.19); C287(1.02)	LDD0746	[9]
LDCM0430	CL40	HCT 116	C108(1.05)	LDD0747	[9]
LDCM0431	CL41	HCT 116	C108(0.70)	LDD0748	[9]
LDCM0432	CL42	HCT 116	C108(1.56)	LDD0749	[9]
LDCM0433	CL43	HCT 116	C108(1.09)	LDD0750	[9]
LDCM0434	CL44	HCT 116	C108(0.75)	LDD0751	[9]
LDCM0435	CL45	HCT 116	C108(1.12)	LDD0752	[9]
LDCM0436	CL46	HEK-293T	C217(0.98)	LDD1034	[9]
LDCM0437	CL47	HEK-293T	C217(0.91)	LDD1035	[9]
LDCM0438	CL48	HEK-293T	C217(0.95)	LDD1036	[9]
LDCM0439	CL49	HEK-293T	C217(1.10)	LDD1037	[9]
LDCM0440	CL5	HCT 116	C108(0.88); C217(1.10); C287(1.05)	LDD0757	[9]
LDCM0441	CL50	HEK-293T	C217(1.40)	LDD1039	[9]
LDCM0442	CL51	HEK-293T	C217(1.16)	LDD1040	[9]
LDCM0443	CL52	HEK-293T	C217(0.88)	LDD1041	[9]
LDCM0444	CL53	HEK-293T	C217(1.06)	LDD1042	[9]
LDCM0445	CL54	HEK-293T	C217(1.04)	LDD1043	[9]
LDCM0446	CL55	HEK-293T	C217(1.04)	LDD1044	[9]
LDCM0447	CL56	HEK-293T	C217(0.99)	LDD1045	[9]
LDCM0448	CL57	HEK-293T	C217(1.22)	LDD1046	[9]
LDCM0449	CL58	HEK-293T	C217(0.98)	LDD1047	[9]
LDCM0450	CL59	HEK-293T	C217(1.16)	LDD1048	[9]
LDCM0451	CL6	HCT 116	C108(1.01); C217(1.03); C287(1.09)	LDD0768	[9]
LDCM0452	CL60	HEK-293T	C217(1.28)	LDD1050	[9]
LDCM0453	CL61	HCT 116	C108(1.07); C217(1.02); C287(1.10)	LDD0770	[9]
LDCM0454	CL62	HCT 116	C108(1.42); C217(1.10); C287(1.28)	LDD0771	[9]
LDCM0455	CL63	HCT 116	C108(1.22); C217(1.09); C287(1.24)	LDD0772	[9]
LDCM0456	CL64	HCT 116	C108(1.29); C217(1.15); C287(1.42)	LDD0773	[9]
LDCM0457	CL65	HCT 116	C108(1.18); C217(1.09); C287(1.30)	LDD0774	[9]
LDCM0458	CL66	HCT 116	C108(1.62); C217(1.35); C287(1.79)	LDD0775	[9]
LDCM0459	CL67	HCT 116	C108(1.35); C217(1.36); C287(1.40)	LDD0776	[9]
LDCM0460	CL68	HCT 116	C108(1.39); C217(1.23); C287(1.33)	LDD0777	[9]
LDCM0461	CL69	HCT 116	C108(0.96); C217(0.86); C287(1.10)	LDD0778	[9]
LDCM0462	CL7	HCT 116	C108(1.07); C217(1.06); C287(1.07)	LDD0779	[9]
LDCM0463	CL70	HCT 116	C108(1.11); C217(1.13); C287(1.26)	LDD0780	[9]
LDCM0464	CL71	HCT 116	C108(1.29); C217(1.19); C287(1.48)	LDD0781	[9]
LDCM0465	CL72	HCT 116	C108(1.05); C217(1.06); C287(1.23)	LDD0782	[9]
LDCM0466	CL73	HCT 116	C108(1.13); C217(1.18); C287(1.29)	LDD0783	[9]
LDCM0467	CL74	HCT 116	C108(1.22); C217(1.33); C287(1.56)	LDD0784	[9]
LDCM0469	CL76	HCT 116	C217(0.79)	LDD0786	[9]
LDCM0470	CL77	HCT 116	C217(0.82)	LDD0787	[9]
LDCM0471	CL78	HCT 116	C217(0.82)	LDD0788	[9]
LDCM0472	CL79	HCT 116	C217(0.97)	LDD0789	[9]
LDCM0473	CL8	HCT 116	C108(1.51); C217(1.28); C287(1.52)	LDD0790	[9]
LDCM0474	CL80	HCT 116	C217(0.80)	LDD0791	[9]
LDCM0475	CL81	HCT 116	C217(0.90)	LDD0792	[9]
LDCM0476	CL82	HCT 116	C217(1.14)	LDD0793	[9]
LDCM0477	CL83	HCT 116	C217(0.99)	LDD0794	[9]
LDCM0478	CL84	HCT 116	C217(1.18)	LDD0795	[9]
LDCM0479	CL85	HCT 116	C217(0.87)	LDD0796	[9]
LDCM0480	CL86	HCT 116	C217(0.77)	LDD0797	[9]
LDCM0481	CL87	HCT 116	C217(0.83)	LDD0798	[9]
LDCM0482	CL88	HCT 116	C217(1.00)	LDD0799	[9]
LDCM0483	CL89	HCT 116	C217(1.18)	LDD0800	[9]
LDCM0484	CL9	HCT 116	C108(0.91); C217(1.11); C287(1.13)	LDD0801	[9]
LDCM0485	CL90	HCT 116	C217(0.96)	LDD0802	[9]
LDCM0486	CL91	HCT 116	C108(1.46); C287(1.08)	LDD0803	[9]
LDCM0487	CL92	HCT 116	C108(1.16); C287(0.95)	LDD0804	[9]
LDCM0488	CL93	HCT 116	C108(1.07); C287(0.90)	LDD0805	[9]
LDCM0489	CL94	HCT 116	C108(1.60); C287(1.01)	LDD0806	[9]
LDCM0490	CL95	HCT 116	C108(1.27); C287(0.91)	LDD0807	[9]
LDCM0491	CL96	HCT 116	C108(1.29); C287(0.84)	LDD0808	[9]
LDCM0492	CL97	HCT 116	C108(1.07); C287(1.02)	LDD0809	[9]
LDCM0493	CL98	HCT 116	C108(1.76); C287(1.33)	LDD0810	[9]
LDCM0494	CL99	HCT 116	C108(1.43); C287(0.98)	LDD0811	[9]
LDCM0033	Curcusone1d	MCF-7	2.07	LDD0188	[5]
LDCM0495	E2913	HEK-293T	C287(1.00); C366(1.02); C108(1.00); C217(0.92)	LDD1698	[20]
LDCM0625	F8	Ramos	C108(0.42); C366(1.07); C287(0.73)	LDD2187	[21]
LDCM0572	Fragment10	Ramos	C108(0.56); C366(2.29)	LDD2189	[21]
LDCM0573	Fragment11	Ramos	C366(1.09); C287(0.79)	LDD2190	[21]
LDCM0574	Fragment12	Ramos	C108(1.17); C366(3.65)	LDD2191	[21]
LDCM0575	Fragment13	Ramos	C108(0.59); C366(0.88)	LDD2192	[21]
LDCM0576	Fragment14	Ramos	C108(1.27); C287(1.10)	LDD2193	[21]
LDCM0579	Fragment20	Ramos	C108(1.05)	LDD2194	[21]
LDCM0580	Fragment21	Ramos	C108(0.70); C366(0.84)	LDD2195	[21]
LDCM0582	Fragment23	Ramos	C108(1.19); C366(1.77)	LDD2196	[21]
LDCM0578	Fragment27	Ramos	C108(0.72); C366(0.70)	LDD2197	[21]
LDCM0586	Fragment28	Ramos	C108(1.61); C366(1.09); C287(0.75)	LDD2198	[21]
LDCM0588	Fragment30	Ramos	C108(0.58); C366(1.00)	LDD2199	[21]
LDCM0589	Fragment31	Ramos	C108(1.12); C366(1.93)	LDD2200	[21]
LDCM0590	Fragment32	Ramos	C108(0.76); C366(3.20)	LDD2201	[21]
LDCM0468	Fragment33	HCT 116	C108(1.39); C217(1.31); C287(1.35)	LDD0785	[9]
LDCM0596	Fragment38	Ramos	C108(0.40); C366(1.45)	LDD2203	[21]
LDCM0566	Fragment4	Ramos	C108(1.24); C366(2.80); C287(0.71)	LDD2184	[21]
LDCM0427	Fragment51	HCT 116	C108(0.96)	LDD0744	[9]
LDCM0610	Fragment52	Ramos	C108(0.48); C366(1.17)	LDD2204	[21]
LDCM0614	Fragment56	Ramos	C108(0.53); C366(0.78)	LDD2205	[21]
LDCM0569	Fragment7	Ramos	C108(0.81); C366(3.04); C287(0.59)	LDD2186	[21]
LDCM0571	Fragment9	Ramos	C108(1.05)	LDD2188	[21]
LDCM0022	KB02	HCT 116	C287(2.77)	LDD0080	[9]
LDCM0023	KB03	HCT 116	C287(1.80)	LDD0081	[9]
LDCM0024	KB05	HCT 116	C287(2.54)	LDD0082	[9]
LDCM0627	NUDT7-COV-1	HEK-293T	C366(0.59)	LDD2206	[22]
LDCM0628	OTUB2-COV-1	HEK-293T	C184(0.37); C366(0.29)	LDD2207	[22]
LDCM0014	Panhematin	HEK-293T	5.52	LDD0062	[8]

References

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6	Appendage and Scaffold Diverse Fully Functionalized Small-Molecule Probes via a Minimalist Terminal Alkyne-Aliphatic Diazirine Isocyanide. J Org Chem. 2018 Sep 21;83(18):11245-11253. doi: 10.1021/acs.joc.8b01831. Epub 2018 Aug 31.
7	Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z. Mass spectrometry data entry: PXD044625
8	A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12. Mass spectrometry data entry: PXD034651
9	Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
10	Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23. Mass spectrometry data entry: PXD028853
11	Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24. Mass spectrometry data entry: PXD029255
12	Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20. Mass spectrometry data entry: PXD022279
13	A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21. Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
14	Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
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16	Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Mass spectrometry data entry: PXD041587
17	Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
18	Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
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Prof. Feng Zhu

Prof. Feng Ni