Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C235  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 161 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05917  Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) 99.7
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 99.7
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 92.4
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 87.4
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 81.6
 LDTP07831  Transmembrane protein with metallophosphoesterase domain (TMPPE) 79.3
 LDTP03540  Heme oxygenase 2 (HMOX2) 78.8
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 77.2
 LDTP09285  Atypical kinase COQ8A, mitochondrial (COQ8A) 75.6
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 74.0
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 71.5
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 64.4
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 63.1
 LDTP04581  Holocytochrome c-type synthase (HCCS) 62.2
 LDTP00697  Cytochrome b5 type B (CYB5B) 61.0
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 55.3
 LDTP04689  Adenosine kinase (ADK) 53.8
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 49.5
 LDTP09251  Atlastin-2 (ATL2) 49.2
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 47.2
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 45.9
 LDTP00325  Pirin (PIR) 45.3
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 44.0
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 43.7
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 43.4
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 42.5
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 41.4
 LDTP08598  NAD-dependent protein deacetylase sirtuin-2 (SIRT2) 41.1
 LDTP10020  Ras-related protein Rab-24 (RAB24) 40.8
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 40.2
 LDTP12293  Adipocyte plasma membrane-associated protein (APMAP) 39.7
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 39.7
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 39.7
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 38.3
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 37.0
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 36.8
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 36.8
 LDTP03145  Catechol O-methyltransferase (COMT) 36.5
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 36.5
 LDTP07931  Heme A synthase COX15 (COX15) 36.0
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 36.0
 LDTP02359  Heme oxygenase 1 (HMOX1) 35.5
 LDTP10329  Ceramide synthase 2 (CERS2) 35.0
 LDTP00836  ATPase GET3 (GET3) 34.8
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 34.5
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 34.3
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 34.1
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 33.8
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 33.1
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 32.0
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 32.0
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 32.0
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 31.6
 LDTP10201  Atypical kinase COQ8B, mitochondrial (COQ8B) 31.1
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 31.1
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 31.1
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 30.9
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 30.9
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 30.7
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 30.3
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 29.9
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 29.7
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 29.2
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 29.2
 LDTP01219  NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) 28.8
 LDTP05905  Acid ceramidase (ASAH1) 28.2
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 28.2
 LDTP04892  Ras-related protein Rab-2A (RAB2A) 28.2
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 27.7
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 27.5
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 27.5
 LDTP00544  Sphingolipid delta(4)-desaturase DES1 (DEGS1) 27.3
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 26.5
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 26.5
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 26.4
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 26.4
 LDTP00344  Stearoyl-CoA desaturase (SCD) 25.5
 LDTP14427  Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) 25.1
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 25.1
 LDTP11733  Ras-related protein Rab-1B (RAB1B) 24.9
 LDTP07483  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) 24.8
 LDTP03051  Ras-related protein Rab-6A (RAB6A) 24.6
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 24.4
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 24.4
 LDTP11723  Cytosolic 5'-nucleotidase 3A (NT5C3A) 24.3
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 24.3
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 23.9
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 23.8
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 23.6
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 23.6
 LDTP06142  Squalene monooxygenase (SQLE) 23.4
 LDTP04895  Ras-related protein Rab-10 (RAB10) 23.1
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 22.8
 LDTP06617  Ceramide glucosyltransferase (UGCG) 22.6
 LDTP06371  GTP-binding protein Rheb (RHEB) 22.6
 LDTP08455  Palmitoyltransferase ZDHHC13 (ZDHHC13) 22.6
 LDTP12415  Adenosine 5'-monophosphoramidase HINT3 (HINT3) 22.3
 LDTP06839  NAD kinase 2, mitochondrial (NADK2) 22.3
 LDTP08530  Mitofusin-1 (MFN1) 21.6
 LDTP05588  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) 21.6
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 21.4
 LDTP06657  2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) 21.0
 LDTP01389  Delta(14)-sterol reductase TM7SF2 (TM7SF2) 20.8
 LDTP10362  Alpha/beta hydrolase domain-containing protein 17A (ABHD17A) 20.5
 LDTP00589  Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) 20.5
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 20.5
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 20.4
 LDTP16040  Glyoxalase domain-containing protein 4 (GLOD4) 20.4
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 20.4
 LDTP02757  Cytochrome b-c1 complex subunit 7 (UQCRB) 20.3
 LDTP12752  NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial (NDUFB11) 20.3
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 20.3
 LDTP12312  Ras-related protein Rab-18 (RAB18) 20.3
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 20.0
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 20.0
 LDTP11842  Inorganic pyrophosphatase 2, mitochondrial (PPA2) 19.7
 LDTP06322  [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (PDK3) 19.7
 LDTP10432  ATP synthase membrane subunit K, mitochondrial (ATP5MK) 19.6
 LDTP02539  Lysosomal acid phosphatase (ACP2) 19.6
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 19.6
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 19.4
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 19.4
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 19.3
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 19.3
 LDTP06810  Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) 19.3
 LDTP03163  Sterol carrier protein 2 (SCP2) 19.2
 LDTP01168  NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) 19.0
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 19.0
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 18.9
 LDTP02283  Cytochrome c1, heme protein, mitochondrial (CYC1) 18.9
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 18.8
 LDTP00464  Glutathione S-transferase 3, mitochondrial (MGST3) 18.6
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 18.5
 LDTP06320  [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) 18.5
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 18.4
 LDTP07525  Protein arginine N-methyltransferase 9 (PRMT9) 18.3
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 18.1
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 18.1
 LDTP02713  Macrophage migration inhibitory factor (MIF) 18.1
 LDTP01659  Ras-related protein Rab-3D (RAB3D) 18.0
 LDTP08799  Lysophosphatidylserine lipase ABHD12 (ABHD12) 17.9
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 17.8
 LDTP06384  Ribosomal protein S6 kinase alpha-1 (RPS6KA1) 17.8
 LDTP00400  Torsin-1B (TOR1B) 17.8
 LDTP11535  Ras-related protein Rab-34 (RAB34) 17.6
 LDTP01573  Acyl-protein thioesterase 2 (LYPLA2) 17.5
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 17.5
 LDTP03662  Long-chain-fatty-acid--CoA ligase 1 (ACSL1) 17.5
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 17.5
 LDTP09578  Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (PTPMT1) 17.5
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 17.4
 LDTP12180  Retinol dehydrogenase 14 (RDH14) 17.4
 LDTP04471  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) 17.4
 LDTP00293  Cytochrome c oxidase subunit NDUFA4 (NDUFA4) 17.3
 LDTP03050  Ras-related protein Rab-5A (RAB5A) 17.3
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 17.1
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 17.1
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 17.0
 LDTP04183  Lanosterol synthase (LSS) 16.9
 LDTP16070  Epimerase family protein SDR39U1 (SDR39U1) 16.8
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 16.8
Transporter and channel
Click to Show/Hide to Show 132 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15648  BRI3-binding protein (BRI3BP) 99.7
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 99.7
 LDTP16813  Tetraspanin-3 (TSPAN3) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 96.3
 LDTP01804  ATP synthase subunit a (MT-ATP6) 81.0
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 77.2
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 77.2
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 76.6
 LDTP11927  Essential MCU regulator, mitochondrial (SMDT1) 73.5
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 71.5
 LDTP00592  Surfeit locus protein 4 (SURF4) 71.5
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 70.0
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 66.3
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 65.8
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 64.9
 LDTP15481  Transmembrane protein 87A (TMEM87A) 63.1
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 62.2
 LDTP08469  Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) 61.0
 LDTP07156  Protein wntless homolog (WLS) 59.7
 LDTP15948  Transmembrane protein 126A (TMEM126A) 58.1
 LDTP20002  Transmembrane protein 160 (TMEM160) 53.8
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 52.7
 LDTP14181  Peroxisomal membrane protein PEX16 (PEX16) 52.7
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 52.3
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 51.3
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 50.2
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 50.2
 LDTP10065  Transmembrane protein 230 (TMEM230) 47.8
 LDTP08881  Transmembrane protein 199 (TMEM199) 47.5
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 46.5
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 43.4
 LDTP12383  Protein GPR108 (GPR108) 42.2
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 40.8
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 40.8
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 39.9
 LDTP11281  Voltage-gated monoatomic cation channel TMEM109 (TMEM109) 39.7
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 39.4
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 39.1
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 39.1
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 39.1
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 39.1
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 38.6
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 35.5
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 35.0
 LDTP15000  Solute carrier family 35 member F1 (SLC35F1) 34.5
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 33.4
 LDTP13833  Integral membrane protein 2B (ITM2B) 33.4
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 33.1
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 32.9
 LDTP07667  Transmembrane protein 205 (TMEM205) 32.9
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 32.4
 LDTP07058  Transmembrane protein 201 (TMEM201) 32.4
 LDTP00590  Protein RER1 (RER1) 32.2
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 31.8
 LDTP12191  Vezatin (VEZT) 31.6
 LDTP01060  PRA1 family protein 2 (PRAF2) 30.9
 LDTP04787  Transmembrane protein 33 (TMEM33) 30.9
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 30.7
 LDTP02215  Prosaposin (PSAP) 30.7
 LDTP11250  MICOS complex subunit MIC26 (APOO) 30.5
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 30.3
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 30.3
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 29.9
 LDTP07531  Sideroflexin-4 (SFXN4) 29.9
 LDTP09261  Major facilitator superfamily domain-containing protein 8 (MFSD8) 29.7
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 29.4
 LDTP06221  StAR-related lipid transfer protein 3 (STARD3) 29.4
 LDTP10731  Sodium-coupled neutral amino acid symporter 2 (SLC38A2) 29.2
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 29.0
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 28.1
 LDTP02266  Synaptophysin (SYP) 27.3
 LDTP11245  Derlin-1 (DERL1) 27.1
 LDTP11615  Protein tweety homolog 3 (TTYH3) 27.1
 LDTP01454  SUN domain-containing protein 1 (SUN1) 26.9
 LDTP11732  Magnesium transporter protein 1 (MAGT1) 26.7
 LDTP01352  PRA1 family protein 3 (ARL6IP5) 26.7
 LDTP10343  Vacuole membrane protein 1 (VMP1) 26.4
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 25.8
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 25.6
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 25.6
 LDTP05780  Syntaxin-5 (STX5) 25.5
 LDTP03546  Translocator protein (TSPO) 25.5
 LDTP09288  Vang-like protein 1 (VANGL1) 25.5
 LDTP11213  Nucleoporin NDC1 (NDC1) 25.3
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 25.1
 LDTP05900  Metaxin-1 (MTX1) 24.8
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 24.4
 LDTP06994  ER membrane protein complex subunit 4 (EMC4) 24.4
 LDTP12958  ER membrane protein complex subunit 3 (EMC3) 24.1
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 23.9
 LDTP16190  Protein FAM8A1 (FAM8A1) 23.9
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 23.8
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 22.9
 LDTP03064  Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) 22.9
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 22.5
 LDTP12533  Ubiquilin-4 (UBQLN4) 22.5
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 22.5
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 22.3
 LDTP17362  Magnesium transporter NIPA3 (NIPAL1) 22.3
 LDTP01380  Wolframin (WFS1) 22.3
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 22.0
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 22.0
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 21.7
 LDTP01631  Mitochondrial pyruvate carrier 2 (MPC2) 21.4
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 21.4
 LDTP07152  Acyl-CoA-binding domain-containing protein 5 (ACBD5) 21.1
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 21.0
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 21.0
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 21.0
 LDTP07462  MFS-type transporter SLC18B1 (SLC18B1) 20.8
 LDTP05667  Syntaxin-4 (STX4) 20.8
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 20.7
 LDTP04749  Peroxisomal biogenesis factor 3 (PEX3) 20.1
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 20.0
 LDTP07236  Protein GPR107 (GPR107) 19.8
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 19.7
 LDTP00546  Secretory carrier-associated membrane protein 1 (SCAMP1) 19.6
 LDTP10148  Store-operated calcium entry-associated regulatory factor (SARAF) 19.4
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 19.3
 LDTP03405  Calnexin (CANX) 19.2
 LDTP12979  Transmembrane protein 14C (TMEM14C) 19.2
 LDTP11812  Protein ARV1 (ARV1) 18.6
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 18.5
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 18.0
 LDTP01217  Metaxin-2 (MTX2) 17.9
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 17.6
 LDTP10370  Solute carrier family 41 member 3 (SLC41A3) 17.4
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 17.4
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 16.9
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 16.9
 LDTP11041  Calcium uptake protein 1, mitochondrial (MICU1) 16.8
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 19.6
Immunoglobulin
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 24.3
 LDTP03772  Basigin (BSG) 16.9
Other
Click to Show/Hide to Show 105 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11076  Apolipoprotein L2 (APOL2) 99.7
 LDTP16078  Heme-binding protein 1 (HEBP1) 99.7
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 99.7
 LDTP10056  Protein FAM162A (FAM162A) 99.7
 LDTP01522  Reticulon-3 (RTN3) 99.7
 LDTP10203  RalBP1-associated Eps domain-containing protein 1 (REPS1) 89.9
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 88.6
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 86.2
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 74.5
 LDTP14458  Tetraspanin-6 (TSPAN6) 73.5
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 72.5
 LDTP01494  Protein YIF1A (YIF1A) 70.5
 LDTP12982  Mitochondrial import receptor subunit TOM7 homolog (TOMM7) 69.6
 LDTP03520  Phosphatidylethanolamine-binding protein 1 (PEBP1) 69.1
 LDTP08224  Protein LYRIC (MTDH) 65.8
 LDTP12412  Reticulon-4 (RTN4) 64.0
 LDTP16006  Optic atrophy 3 protein (OPA3) 63.1
 LDTP14939  Membralin (TMEM259) 57.7
 LDTP00859  Synaptogyrin-2 (SYNGR2) 53.4
 LDTP16080  Protein FAM114A2 (FAM114A2) 50.9
 LDTP13086  Syntaxin-18 (STX18) 44.0
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 43.4
 LDTP19963  TraB domain-containing protein (TRABD) 42.8
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 41.4
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 40.8
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 39.4
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 38.3
 LDTP01167  Reticulon-2 (RTN2) 36.5
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 35.8
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 35.3
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 34.5
 LDTP08248  NLR family member X1 (NLRX1) 33.4
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 33.4
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 33.1
 LDTP10357  RUS family member 1 (RUSF1) 32.4
 LDTP05160  Nucleobindin-2 (NUCB2) 31.3
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 31.3
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 30.9
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 30.3
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 30.1
 LDTP14716  ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) 29.7
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 28.6
 LDTP19472  Protein NCBP2AS2 (NCBP2AS2) 28.1
 LDTP18272  Transmembrane protein 209 (TMEM209) 28.1
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 27.7
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 26.9
 LDTP04558  Arfaptin-1 (ARFIP1) 26.5
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 26.0
 LDTP13982  Mitochondrial fission 1 protein (FIS1) 26.0
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 25.3
 LDTP08058  Mitochondrial antiviral-signaling protein (MAVS) 25.3
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 25.3
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 24.1
 LDTP08300  Reticulophagy regulator 3 (RETREG3) 24.1
 LDTP18132  Protein FAM136A (FAM136A) 23.9
 LDTP11044  Polyadenylate-binding protein-interacting protein 2 (PAIP2) 23.8
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 23.6
 LDTP05054  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) 23.4
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 23.3
 LDTP06373  Mitochondrial import receptor subunit TOM20 homolog (TOMM20) 22.8
 LDTP10924  Prohibitin-2 (PHB2) 22.6
 LDTP12606  Structural maintenance of chromosomes protein 4 (SMC4) 22.6
 LDTP06097  Reticulocalbin-2 (RCN2) 22.3
 LDTP00887  Calumenin (CALU) 22.2
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 22.0
 LDTP07655  Pre-mRNA 3'-end-processing factor FIP1 (FIP1L1) 22.0
 LDTP13622  NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) 21.9
 LDTP00875  Striatin (STRN) 21.9
 LDTP04356  Emerin (EMD) 21.7
 LDTP05868  Protein unc-119 homolog A (UNC119) 21.7
 LDTP15778  Protein PRRC1 (PRRC1) 21.1
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 20.7
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 20.7
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 20.4
 LDTP01652  Centrosomal protein 43 (CEP43) 20.3
 LDTP11140  Peroxiredoxin-like 2A (PRXL2A) 20.3
 LDTP05041  Guanine nucleotide-binding protein G(i) subunit alpha-1 (GNAI1) 20.1
 LDTP10207  Mitochondrial import inner membrane translocase subunit TIM14 (DNAJC19) 20.0
 LDTP18435  Plasminogen receptor (KT) (PLGRKT) 19.8
 LDTP12677  DnaJ homolog subfamily C member 11 (DNAJC11) 19.4
 LDTP06527  Alpha-internexin (INA) 19.3
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 19.3
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 18.9
 LDTP13664  Syntaxin-8 (STX8) 18.6
 LDTP11910  Golgi phosphoprotein 3-like (GOLPH3L) 18.5
 LDTP12692  Armadillo repeat-containing protein 1 (ARMC1) 18.4
 LDTP00105  Protein unc-119 homolog B (UNC119B) 18.3
 LDTP10113  Mitochondrial import receptor subunit TOM6 homolog (TOMM6) 18.1
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 18.1
 LDTP10469  Engulfment and cell motility protein 2 (ELMO2) 18.0
 LDTP05226  RNA-binding protein 3 (RBM3) 17.6
 LDTP16285  Transducin beta-like protein 2 (TBL2) 17.6
 LDTP11239  Protein misato homolog 1 (MSTO1) 17.4
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 17.3
 LDTP01711  Protein ecdysoneless homolog (ECD) 17.3
 LDTP09881  TATA-binding protein-associated factor 2N (TAF15) 17.3
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 17.1
 LDTP05960  Trophoblast glycoprotein (TPBG) 17.1
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 17.0
 LDTP15398  Protein FAM177A1 (FAM177A1) 17.0
 LDTP06404  Surfeit locus protein 1 (SURF1) 17.0
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 16.8
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 16.8
 LDTP03615  Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) 16.8
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 16.7

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587