Details of the Target

General Information of Target

Target ID LDTP02266
Target Name Synaptophysin (SYP)
Gene Name SYP
Gene ID 6855
Synonyms
Synaptophysin; Major synaptic vesicle protein p38
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANK
TESDLSIEVEFEYPFRLHQVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMG
ALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEM
PVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAP
EKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGDYGQQGY
GPQGAPTSFSNQM
Target Bioclass
Transporter and channel
Family
Synaptophysin/synaptobrevin family
Subcellular location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Function
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Uniprot ID
P08247
Ensemble ID
ENST00000263233.9
HGNC ID
HGNC:11506

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.V97I .
JURKAT Deletion: p.E241RfsTer193 .
NCIH1993 SNV: p.A239S .
OVCAR5 SNV: p.V155I .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C72(1.59)  LDD3340  [1]
BTD
 Probe Info  		C190(0.66)  LDD2099  [2]
FBPP2
 Probe Info  		2.85  LDD0054  [3]
IPM
 Probe Info  		C190(0.00); C87(0.00)  LDD2156  [4]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C231
 Probe Info  		24.08  LDD1904  [5]
C235
 Probe Info  		27.28  LDD1908  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C190(1.07); C87(1.04)  LDD1507  [6]
 LDCM0215  AC10 HEK-293T C190(1.07); C87(1.08)  LDD1508  [6]
 LDCM0226  AC11 HEK-293T C190(1.00); C87(1.09)  LDD1509  [6]
 LDCM0237  AC12 HEK-293T C190(0.98); C87(1.08)  LDD1510  [6]
 LDCM0259  AC14 HEK-293T C190(1.05); C87(1.02)  LDD1512  [6]
 LDCM0270  AC15 HEK-293T C190(0.91); C87(1.01)  LDD1513  [6]
 LDCM0276  AC17 HEK-293T C190(1.04); C87(1.04)  LDD1515  [6]
 LDCM0277  AC18 HEK-293T C190(1.08); C87(1.19)  LDD1516  [6]
 LDCM0278  AC19 HEK-293T C190(1.43); C87(1.17)  LDD1517  [6]
 LDCM0279  AC2 HEK-293T C190(1.08); C87(0.98)  LDD1518  [6]
 LDCM0280  AC20 HEK-293T C190(1.09); C87(1.08)  LDD1519  [6]
 LDCM0281  AC21 HEK-293T C190(0.97); C87(0.94)  LDD1520  [6]
 LDCM0282  AC22 HEK-293T C190(0.97); C87(1.02)  LDD1521  [6]
 LDCM0283  AC23 HEK-293T C190(0.94); C87(0.89)  LDD1522  [6]
 LDCM0284  AC24 HEK-293T C190(0.98); C87(0.90)  LDD1523  [6]
 LDCM0285  AC25 HEK-293T C190(1.09); C87(0.96)  LDD1524  [6]
 LDCM0286  AC26 HEK-293T C190(1.11); C87(1.11)  LDD1525  [6]
 LDCM0287  AC27 HEK-293T C190(1.03); C87(1.04)  LDD1526  [6]
 LDCM0288  AC28 HEK-293T C190(0.97); C87(1.05)  LDD1527  [6]
 LDCM0289  AC29 HEK-293T C190(0.96); C87(0.94)  LDD1528  [6]
 LDCM0290  AC3 HEK-293T C190(0.98); C87(1.04)  LDD1529  [6]
 LDCM0291  AC30 HEK-293T C190(1.07); C87(0.98)  LDD1530  [6]
 LDCM0292  AC31 HEK-293T C190(0.97); C87(1.05)  LDD1531  [6]
 LDCM0293  AC32 HEK-293T C190(1.01); C87(0.91)  LDD1532  [6]
 LDCM0294  AC33 HEK-293T C190(0.99); C87(0.85)  LDD1533  [6]
 LDCM0295  AC34 HEK-293T C190(1.05); C87(1.06)  LDD1534  [6]
 LDCM0296  AC35 HEK-293T C190(0.92); C87(0.95)  LDD1535  [6]
 LDCM0297  AC36 HEK-293T C190(0.79); C87(0.96)  LDD1536  [6]
 LDCM0298  AC37 HEK-293T C190(0.86); C87(1.01)  LDD1537  [6]
 LDCM0299  AC38 HEK-293T C190(0.97); C87(1.10)  LDD1538  [6]
 LDCM0300  AC39 HEK-293T C190(0.86); C87(0.97)  LDD1539  [6]
 LDCM0301  AC4 HEK-293T C190(1.05); C87(1.09)  LDD1540  [6]
 LDCM0302  AC40 HEK-293T C190(0.94); C87(1.07)  LDD1541  [6]
 LDCM0303  AC41 HEK-293T C190(1.00); C87(0.97)  LDD1542  [6]
 LDCM0304  AC42 HEK-293T C190(1.11); C87(0.97)  LDD1543  [6]
 LDCM0305  AC43 HEK-293T C190(0.93); C87(1.02)  LDD1544  [6]
 LDCM0306  AC44 HEK-293T C190(0.89); C87(1.08)  LDD1545  [6]
 LDCM0307  AC45 HEK-293T C190(0.90); C87(0.95)  LDD1546  [6]
 LDCM0308  AC46 HEK-293T C190(0.93); C87(1.06)  LDD1547  [6]
 LDCM0309  AC47 HEK-293T C190(0.91); C87(0.99)  LDD1548  [6]
 LDCM0310  AC48 HEK-293T C190(0.89); C87(0.99)  LDD1549  [6]
 LDCM0311  AC49 HEK-293T C190(0.98); C87(0.95)  LDD1550  [6]
 LDCM0312  AC5 HEK-293T C190(0.96); C87(0.95)  LDD1551  [6]
 LDCM0313  AC50 HEK-293T C190(1.04); C87(1.06)  LDD1552  [6]
 LDCM0314  AC51 HEK-293T C190(0.96); C87(0.97)  LDD1553  [6]
 LDCM0315  AC52 HEK-293T C190(1.03); C87(1.07)  LDD1554  [6]
 LDCM0316  AC53 HEK-293T C190(0.90); C87(0.90)  LDD1555  [6]
 LDCM0317  AC54 HEK-293T C190(1.01); C87(0.96)  LDD1556  [6]
 LDCM0318  AC55 HEK-293T C190(0.88); C87(1.06)  LDD1557  [6]
 LDCM0319  AC56 HEK-293T C190(0.93); C87(1.04)  LDD1558  [6]
 LDCM0320  AC57 HEK-293T C190(1.12); C87(1.12)  LDD1559  [6]
 LDCM0321  AC58 HEK-293T C190(1.12); C87(1.23)  LDD1560  [6]
 LDCM0322  AC59 HEK-293T C190(0.99); C87(0.98)  LDD1561  [6]
 LDCM0323  AC6 HEK-293T C190(1.06); C87(0.98)  LDD1562  [6]
 LDCM0324  AC60 HEK-293T C190(0.95); C87(1.08)  LDD1563  [6]
 LDCM0325  AC61 HEK-293T C190(0.99); C87(0.99)  LDD1564  [6]
 LDCM0326  AC62 HEK-293T C190(1.09); C87(1.00)  LDD1565  [6]
 LDCM0327  AC63 HEK-293T C190(0.97); C87(1.13)  LDD1566  [6]
 LDCM0328  AC64 HEK-293T C190(0.99); C87(0.97)  LDD1567  [6]
 LDCM0334  AC7 HEK-293T C190(1.00); C87(1.01)  LDD1568  [6]
 LDCM0345  AC8 HEK-293T C190(0.96); C87(1.05)  LDD1569  [6]
 LDCM0248  AKOS034007472 HEK-293T C190(0.97); C87(0.95)  LDD1511  [6]
 LDCM0356  AKOS034007680 HEK-293T C190(1.06); C87(0.95)  LDD1570  [6]
 LDCM0275  AKOS034007705 HEK-293T C190(0.97); C87(1.07)  LDD1514  [6]
 LDCM0367  CL1 HEK-293T C190(1.03); C87(1.12)  LDD1571  [6]
 LDCM0368  CL10 HEK-293T C190(1.26); C87(1.62)  LDD1572  [6]
 LDCM0369  CL100 HEK-293T C190(1.05); C87(0.97)  LDD1573  [6]
 LDCM0370  CL101 HEK-293T C190(1.05); C87(1.08)  LDD1574  [6]
 LDCM0371  CL102 HEK-293T C190(1.02); C87(1.02)  LDD1575  [6]
 LDCM0372  CL103 HEK-293T C190(0.92); C87(0.89)  LDD1576  [6]
 LDCM0373  CL104 HEK-293T C190(0.98); C87(1.00)  LDD1577  [6]
 LDCM0374  CL105 HEK-293T C190(1.04); C87(1.01)  LDD1578  [6]
 LDCM0375  CL106 HEK-293T C190(1.06); C87(0.98)  LDD1579  [6]
 LDCM0376  CL107 HEK-293T C190(0.90); C87(0.88)  LDD1580  [6]
 LDCM0377  CL108 HEK-293T C190(1.01); C87(1.06)  LDD1581  [6]
 LDCM0378  CL109 HEK-293T C190(0.99); C87(1.18)  LDD1582  [6]
 LDCM0379  CL11 HEK-293T C190(0.81); C87(1.08)  LDD1583  [6]
 LDCM0380  CL110 HEK-293T C190(1.08); C87(1.00)  LDD1584  [6]
 LDCM0381  CL111 HEK-293T C190(0.91); C87(0.99)  LDD1585  [6]
 LDCM0382  CL112 HEK-293T C190(1.04); C87(1.00)  LDD1586  [6]
 LDCM0383  CL113 HEK-293T C190(0.99); C87(0.99)  LDD1587  [6]
 LDCM0384  CL114 HEK-293T C190(1.05); C87(0.97)  LDD1588  [6]
 LDCM0385  CL115 HEK-293T C190(0.98); C87(0.89)  LDD1589  [6]
 LDCM0386  CL116 HEK-293T C190(0.99); C87(0.90)  LDD1590  [6]
 LDCM0387  CL117 HEK-293T C190(1.00); C87(1.01)  LDD1591  [6]
 LDCM0388  CL118 HEK-293T C190(1.07); C87(0.95)  LDD1592  [6]
 LDCM0389  CL119 HEK-293T C190(1.05); C87(0.91)  LDD1593  [6]
 LDCM0390  CL12 HEK-293T C190(1.06); C87(1.02)  LDD1594  [6]
 LDCM0391  CL120 HEK-293T C190(1.04); C87(0.88)  LDD1595  [6]
 LDCM0392  CL121 HEK-293T C190(0.98); C87(1.01)  LDD1596  [6]
 LDCM0393  CL122 HEK-293T C190(0.96); C87(1.06)  LDD1597  [6]
 LDCM0394  CL123 HEK-293T C190(1.10); C87(0.88)  LDD1598  [6]
 LDCM0395  CL124 HEK-293T C190(1.05); C87(1.00)  LDD1599  [6]
 LDCM0396  CL125 HEK-293T C190(1.17); C87(1.14)  LDD1600  [6]
 LDCM0397  CL126 HEK-293T C190(1.07); C87(1.13)  LDD1601  [6]
 LDCM0398  CL127 HEK-293T C190(1.03); C87(0.92)  LDD1602  [6]
 LDCM0399  CL128 HEK-293T C190(1.07); C87(0.99)  LDD1603  [6]
 LDCM0400  CL13 HEK-293T C190(1.04); C87(1.03)  LDD1604  [6]
 LDCM0401  CL14 HEK-293T C190(1.00); C87(0.87)  LDD1605  [6]
 LDCM0402  CL15 HEK-293T C190(1.32); C87(1.06)  LDD1606  [6]
 LDCM0403  CL16 HEK-293T C190(1.03); C87(0.95)  LDD1607  [6]
 LDCM0404  CL17 HEK-293T C190(1.16); C87(1.13)  LDD1608  [6]
 LDCM0405  CL18 HEK-293T C190(1.04); C87(1.10)  LDD1609  [6]
 LDCM0406  CL19 HEK-293T C190(0.94); C87(1.10)  LDD1610  [6]
 LDCM0407  CL2 HEK-293T C190(1.02); C87(1.04)  LDD1611  [6]
 LDCM0408  CL20 HEK-293T C190(0.89); C87(1.12)  LDD1612  [6]
 LDCM0409  CL21 HEK-293T C190(0.84); C87(1.12)  LDD1613  [6]
 LDCM0410  CL22 HEK-293T C190(1.05); C87(1.09)  LDD1614  [6]
 LDCM0411  CL23 HEK-293T C190(0.78); C87(0.95)  LDD1615  [6]
 LDCM0412  CL24 HEK-293T C190(1.02); C87(0.98)  LDD1616  [6]
 LDCM0413  CL25 HEK-293T C190(1.11); C87(1.14)  LDD1617  [6]
 LDCM0414  CL26 HEK-293T C190(1.00); C87(0.91)  LDD1618  [6]
 LDCM0415  CL27 HEK-293T C190(0.93); C87(0.85)  LDD1619  [6]
 LDCM0416  CL28 HEK-293T C190(1.02); C87(1.01)  LDD1620  [6]
 LDCM0417  CL29 HEK-293T C190(1.00); C87(1.05)  LDD1621  [6]
 LDCM0418  CL3 HEK-293T C190(1.06); C87(0.91)  LDD1622  [6]
 LDCM0419  CL30 HEK-293T C190(1.05); C87(1.21)  LDD1623  [6]
 LDCM0420  CL31 HEK-293T C190(0.99); C87(1.02)  LDD1624  [6]
 LDCM0421  CL32 HEK-293T C190(0.94); C87(1.22)  LDD1625  [6]
 LDCM0422  CL33 HEK-293T C190(0.98); C87(1.32)  LDD1626  [6]
 LDCM0423  CL34 HEK-293T C190(1.05); C87(1.16)  LDD1627  [6]
 LDCM0424  CL35 HEK-293T C190(0.85); C87(1.02)  LDD1628  [6]
 LDCM0425  CL36 HEK-293T C190(0.91); C87(0.96)  LDD1629  [6]
 LDCM0426  CL37 HEK-293T C190(1.03); C87(1.01)  LDD1630  [6]
 LDCM0428  CL39 HEK-293T C190(0.95); C87(0.97)  LDD1632  [6]
 LDCM0429  CL4 HEK-293T C190(1.04); C87(1.08)  LDD1633  [6]
 LDCM0430  CL40 HEK-293T C190(1.01); C87(0.96)  LDD1634  [6]
 LDCM0431  CL41 HEK-293T C190(1.07); C87(1.10)  LDD1635  [6]
 LDCM0432  CL42 HEK-293T C190(1.09); C87(1.20)  LDD1636  [6]
 LDCM0433  CL43 HEK-293T C190(0.95); C87(0.95)  LDD1637  [6]
 LDCM0434  CL44 HEK-293T C190(0.96); C87(1.03)  LDD1638  [6]
 LDCM0435  CL45 HEK-293T C190(0.86); C87(1.12)  LDD1639  [6]
 LDCM0436  CL46 HEK-293T C190(0.98); C87(1.06)  LDD1640  [6]
 LDCM0437  CL47 HEK-293T C190(0.97); C87(1.02)  LDD1641  [6]
 LDCM0438  CL48 HEK-293T C190(0.94); C87(0.98)  LDD1642  [6]
 LDCM0439  CL49 HEK-293T C190(1.00); C87(1.05)  LDD1643  [6]
 LDCM0440  CL5 HEK-293T C190(0.98); C87(1.07)  LDD1644  [6]
 LDCM0441  CL50 HEK-293T C190(0.98); C87(0.97)  LDD1645  [6]
 LDCM0443  CL52 HEK-293T C190(0.95); C87(1.01)  LDD1646  [6]
 LDCM0444  CL53 HEK-293T C190(1.03); C87(1.18)  LDD1647  [6]
 LDCM0445  CL54 HEK-293T C190(1.07); C87(1.15)  LDD1648  [6]
 LDCM0446  CL55 HEK-293T C190(0.89); C87(1.07)  LDD1649  [6]
 LDCM0447  CL56 HEK-293T C190(0.83); C87(1.14)  LDD1650  [6]
 LDCM0448  CL57 HEK-293T C190(0.86); C87(1.28)  LDD1651  [6]
 LDCM0449  CL58 HEK-293T C190(0.97); C87(1.07)  LDD1652  [6]
 LDCM0450  CL59 HEK-293T C190(0.83); C87(1.04)  LDD1653  [6]
 LDCM0451  CL6 HEK-293T C190(1.14); C87(1.42)  LDD1654  [6]
 LDCM0452  CL60 HEK-293T C190(0.96); C87(1.02)  LDD1655  [6]
 LDCM0453  CL61 HEK-293T C190(1.07); C87(0.98)  LDD1656  [6]
 LDCM0454  CL62 HEK-293T C190(0.94); C87(0.96)  LDD1657  [6]
 LDCM0455  CL63 HEK-293T C190(0.88); C87(0.83)  LDD1658  [6]
 LDCM0456  CL64 HEK-293T C190(1.02); C87(1.03)  LDD1659  [6]
 LDCM0457  CL65 HEK-293T C190(1.02); C87(1.03)  LDD1660  [6]
 LDCM0458  CL66 HEK-293T C190(1.07); C87(1.12)  LDD1661  [6]
 LDCM0459  CL67 HEK-293T C190(0.93); C87(1.14)  LDD1662  [6]
 LDCM0460  CL68 HEK-293T C190(1.10); C87(1.12)  LDD1663  [6]
 LDCM0461  CL69 HEK-293T C190(0.87); C87(1.15)  LDD1664  [6]
 LDCM0462  CL7 HEK-293T C190(0.90); C87(1.13)  LDD1665  [6]
 LDCM0463  CL70 HEK-293T C190(1.02); C87(0.95)  LDD1666  [6]
 LDCM0464  CL71 HEK-293T C190(0.81); C87(1.02)  LDD1667  [6]
 LDCM0465  CL72 HEK-293T C190(0.89); C87(0.87)  LDD1668  [6]
 LDCM0466  CL73 HEK-293T C190(1.09); C87(1.05)  LDD1669  [6]
 LDCM0467  CL74 HEK-293T C190(0.98); C87(1.00)  LDD1670  [6]
 LDCM0469  CL76 HEK-293T C190(0.98); C87(1.00)  LDD1672  [6]
 LDCM0470  CL77 HEK-293T C190(1.02); C87(1.18)  LDD1673  [6]
 LDCM0471  CL78 HEK-293T C190(1.05); C87(1.03)  LDD1674  [6]
 LDCM0472  CL79 HEK-293T C190(0.94); C87(1.01)  LDD1675  [6]
 LDCM0473  CL8 HEK-293T C190(1.07); C87(1.80)  LDD1676  [6]
 LDCM0474  CL80 HEK-293T C190(0.86); C87(1.05)  LDD1677  [6]
 LDCM0475  CL81 HEK-293T C190(0.85); C87(0.99)  LDD1678  [6]
 LDCM0476  CL82 HEK-293T C190(1.00); C87(0.97)  LDD1679  [6]
 LDCM0477  CL83 HEK-293T C190(0.85); C87(1.18)  LDD1680  [6]
 LDCM0478  CL84 HEK-293T C190(0.93); C87(0.95)  LDD1681  [6]
 LDCM0479  CL85 HEK-293T C190(1.05); C87(0.95)  LDD1682  [6]
 LDCM0480  CL86 HEK-293T C190(0.98); C87(1.16)  LDD1683  [6]
 LDCM0481  CL87 HEK-293T C190(0.98); C87(0.84)  LDD1684  [6]
 LDCM0482  CL88 HEK-293T C190(1.04); C87(1.07)  LDD1685  [6]
 LDCM0483  CL89 HEK-293T C190(1.01); C87(1.02)  LDD1686  [6]
 LDCM0484  CL9 HEK-293T C190(0.83); C87(1.11)  LDD1687  [6]
 LDCM0485  CL90 HEK-293T C190(1.44); C87(1.44)  LDD1688  [6]
 LDCM0486  CL91 HEK-293T C190(0.94); C87(1.11)  LDD1689  [6]
 LDCM0487  CL92 HEK-293T C190(0.91); C87(1.18)  LDD1690  [6]
 LDCM0488  CL93 HEK-293T C190(0.86); C87(1.11)  LDD1691  [6]
 LDCM0489  CL94 HEK-293T C190(1.02); C87(1.02)  LDD1692  [6]
 LDCM0490  CL95 HEK-293T C190(1.07); C87(1.23)  LDD1693  [6]
 LDCM0491  CL96 HEK-293T C190(0.94); C87(1.10)  LDD1694  [6]
 LDCM0492  CL97 HEK-293T C190(1.05); C87(1.12)  LDD1695  [6]
 LDCM0493  CL98 HEK-293T C190(1.02); C87(1.00)  LDD1696  [6]
 LDCM0494  CL99 HEK-293T C190(0.97); C87(0.88)  LDD1697  [6]
 LDCM0495  E2913 HEK-293T C190(0.89); C87(0.92)  LDD1698  [6]
 LDCM0468  Fragment33 HEK-293T C190(0.98); C87(0.92)  LDD1671  [6]
 LDCM0427  Fragment51 HEK-293T C190(1.00); C87(0.96)  LDD1631  [6]
 LDCM0022  KB02 HEK-293T C190(0.83); C87(1.05)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C190(0.92); C87(1.00)  LDD1497  [6]
 LDCM0024  KB05 NB1 C72(1.59)  LDD3340  [1]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C190(0.66)  LDD2099  [2]
 LDCM0008  Tranylcypromine SH-SY5Y 2.85  LDD0054  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Maspardin (SPG21) AB hydrolase superfamily Q9NZD8
Cullin-associated NEDD8-dissociated protein 2 (CAND2) CAND family O75155
rRNA methyltransferase 1, mitochondrial (MRM1) RNA methyltransferase TrmH family Q6IN84
Phenylalanine--tRNA ligase, mitochondrial (FARS2) Class-II aminoacyl-tRNA synthetase family O95363
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF) Cyclophilin-type PPIase family P30405
Bifunctional polynucleotide phosphatase/kinase (PNKP) DNA 3' phosphatase family Q96T60
MYG1 exonuclease (MYG1) MYG1 family Q9HB07
Peroxynitrite isomerase THAP4 (THAP4) Nitrobindin family Q8WY91
Tyrosine-protein phosphatase non-receptor type 9 (PTPN9) Protein-tyrosine phosphatase family P43378
Josephin-2 (JOSD2) . Q8TAC2
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Amyloid-beta precursor protein (APP) APP family P05067
Endophilin-B1 (SH3GLB1) Endophilin family Q9Y371
Huntingtin (HTT) Huntingtin family P42858
Sorting nexin-1 (SNX1) Sorting nexin family Q13596
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Heat shock transcription factor, X-linked (HSFX1; HSFX2) HSF family Q9UBD0
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CD160 antigen (CD160) . O95971
Other
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transcription termination factor 3, mitochondrial (MTERF3) MTERF family Q96E29
Perilipin-3 (PLIN3) Perilipin family O60664
Pentatricopeptide repeat-containing protein 1, mitochondrial (PTCD1) PTCD1 family O75127
Putative ribosome-binding factor A, mitochondrial (RBFA) RbfA family Q8N0V3
Ribosome-recycling factor, mitochondrial (MRRF) RRF family Q96E11
Mitochondrial dynamics protein MIEF1 (MIEF1) SMCR7 family Q9NQG6
Nonsense-mediated mRNA decay factor SMG9 (SMG9) SMG9 family Q9H0W8
Tubulin beta-2A chain (TUBB2A) Tubulin family Q13885
Arfaptin-2 (ARFIP2) . P53365
Diablo IAP-binding mitochondrial protein (DIABLO) . Q9NR28
StAR-related lipid transfer protein 4 (STARD4) . Q96DR4
WD repeat and FYVE domain-containing protein 2 (WDFY2) . Q96P53

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580
4 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
5 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402