General Information of Probe

Probe ID
LDPC0054
Probe Name
FBPP2
Probe Type
ABPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 269.348
Lipid-water partition coefficient (xlogp) 2.8456
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C16H19N3O
Canonical SMILES
C#CCCC1(CCOc2ccc(C3CC3N)cc2)N=N1
InChI
InChI=1S/C16H19N3O/c1-2-3-8-16(18-19-16)9-10-20-13-6-4-12(5-7-13)14-11-15(14)17/h1,4-7,14-15H,3,8-11,17H2/t14?,15-/m0/s1
InChIKey
AVLRFIDTIQOWMV-LOACHALJSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

120 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-aminoethanethiol dioxygenase (ADO) LDTP10828 4.36  LDD0318 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 6.97  LDD0324 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 8.50  LDD0318 
72 kDa type IV collagenase (MMP2) LDTP02267 24.07  LDD0318 
Acid ceramidase (ASAH1) LDTP05905 152.19  LDD0318 
ADP-ribose glycohydrolase MACROD1 (MACROD1) LDTP11059 8.43  LDD0054 
ADP-ribosylation factor 5 (ARF5) LDTP05193 14.12  LDD0318 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 3.97  LDD0318 
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (MGAT5) LDTP05593 7.71  LDD0318 
Alpha-galactosidase A (GLA) LDTP02141 4.00  LDD0054 
Alpha-L-iduronidase (IDUA) LDTP03748 3.52  LDD0054 
Alpha-N-acetylgalactosaminidase (NAGA) LDTP02883 2.40  LDD0054 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 2.07  LDD0054 
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 (ST8SIA3) LDTP00699 4.47  LDD0318 
Amine oxidase [flavin-containing] A (MAOA) LDTP03109 2.92  LDD0318 
Aminoacylase-1 (ACY1) LDTP05395 2.56  LDD0318 
Arylsulfatase A (ARSA) LDTP02776 3.02  LDD0324 
Arylsulfatase B (ARSB) LDTP02807 2.09  LDD0054 
ATP-binding cassette sub-family B member 6 (ABCB6) LDTP12303 2.98  LDD0318 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 4.40  LDD0318 
Beta-galactosidase (GLB1) LDTP02837 9.03  LDD0318 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 2.97  LDD0054 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 2.99  LDD0054 
Beta-mannosidase (MANBA) LDTP00282 2.11  LDD0054 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 30.18  LDD0318 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 2.73  LDD0318 
Carbohydrate sulfotransferase 12 (CHST12) LDTP12494 8.85  LDD0318 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 6.42  LDD0318 
Carboxypeptidase D (CPD) LDTP01372 7.23  LDD0318 
Carboxypeptidase E (CPE) LDTP02865 2.17  LDD0054 
Cathepsin B (CTSB) LDTP02223 3.35  LDD0054 
Cathepsin D (CTSD) LDTP02198 131.86  LDD0318 
Cathepsin F (CTSF) LDTP13172 3.86  LDD0054 
Cathepsin Z (CTSZ) LDTP13147 14.12  LDD0324 
Ceramide glucosyltransferase (UGCG) LDTP06617 39.88  LDD0318 
Copper-transporting ATPase 1 (ATP7A) LDTP05422 3.60  LDD0318 
Cytochrome b5 type B (CYB5B) LDTP00697 13.66  LDD0318 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 25.72  LDD0318 
Deoxyhypusine synthase (DHPS) LDTP04248 2.92  LDD0324 
Deoxyribonuclease-2-alpha (DNASE2) LDTP00185 2.33  LDD0054 
Di-N-acetylchitobiase (CTBS) LDTP14801 7.33  LDD0054 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 3.17  LDD0318 
Dihydrofolate reductase (DHFR) LDTP01769 6.68  LDD0318 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 2.24  LDD0054 
Dipeptidyl peptidase 2 (DPP7) LDTP13294 3.29  LDD0054 
Discoidin domain-containing receptor 2 (DDR2) LDTP06644 7.36  LDD0318 
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) LDTP05137 2.86  LDD0318 
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22) LDTP12962 7.54  LDD0318 
Dolichyl-phosphate beta-glucosyltransferase (ALG5) LDTP14214 10.61  LDD0318 
Dopamine beta-hydroxylase (DBH) LDTP02331 6.76  LDD0318 
EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) LDTP00888 4.67  LDD0324 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 3.87  LDD0318 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 224.17  LDD0318 
Epoxide hydrolase 1 (EPHX1) LDTP02175 2.82  LDD0318 
Furin (FURIN) LDTP02384 2.62  LDD0324 
Galactocerebrosidase (GALC) LDTP04635 6.21  LDD0318 
Gamma-glutamyl hydrolase (GGH) LDTP09886 2.29  LDD0054 
Gamma-interferon-inducible lysosomal thiol reductase (IFI30) LDTP02651 30.35  LDD0318 
Glucosidase 2 subunit beta (PRKCSH) LDTP02718 2.54  LDD0318 
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (C1GALT1) LDTP12553 2.71  LDD0318 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 2.19  LDD0324 
Heme oxygenase 2 (HMOX2) LDTP03540 12.98  LDD0318 
Heparan-sulfate 6-O-sulfotransferase 2 (HS6ST2) LDTP10591 8.34  LDD0318 
Histamine N-methyltransferase (HNMT) LDTP04341 5.10  LDD0324 
Legumain (LGMN) LDTP10888 3.27  LDD0054 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 13.19  LDD0318 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 4.32  LDD0318 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 2.45  LDD0054 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 39.82  LDD0318 
Lysosomal acid phosphatase (ACP2) LDTP02539 2.01  LDD0054 
Lysosomal alpha-glucosidase (GAA) LDTP02486 5.97  LDD0318 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 7.62  LDD0054 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 3.57  LDD0054 
Lysosomal protective protein (CTSA) LDTP02505 29.57  LDD0318 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 26.02  LDD0318 
Minor histocompatibility antigen H13 (HM13) LDTP09396 2.54  LDD0318 
N-acetylgalactosaminyltransferase 7 (GALNT7) LDTP08164 3.41  LDD0318 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 6.72  LDD0054 
N-sulphoglucosamine sulphohydrolase (SGSH) LDTP04452 3.55  LDD0318 
NAD(P)H-hydrate epimerase (NAXE) LDTP09110 2.66  LDD0318 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 2.76  LDD0318 
NADPH--cytochrome P450 reductase (POR) LDTP02848 2.20  LDD0318 
Neurotrypsin (PRSS12) LDTP04759 2.14  LDD0318 
Oxidized purine nucleoside triphosphate hydrolase (NUDT1) LDTP03816 25.67  LDD0318 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 4.10  LDD0054 
Peptidyl-glycine alpha-amidating monooxygenase (PAM) LDTP02976 19.68  LDD0318 
Phospholipase A2 group XV (PLA2G15) LDTP09088 2.80  LDD0054 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 8.98  LDD0054 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 6.10  LDD0318 
Polypeptide N-acetylgalactosaminyltransferase 13 (GALNT13) LDTP08447 10.58  LDD0318 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 2.05  LDD0318 
Pro-cathepsin H (CTSH) LDTP02366 5.70  LDD0054 
Probable carboxypeptidase X1 (CPXM1) LDTP15831 4.70  LDD0318 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 3.74  LDD0054 
Procathepsin L (CTSL) LDTP02217 7.07  LDD0054 
Procollagen C-endopeptidase enhancer 1 (PCOLCE) LDTP06318 92.98  LDD0318 
Prostaglandin reductase 2 (PTGR2) LDTP08979 18.17  LDD0318 
Protein disulfide isomerase CRELD1 (CRELD1) LDTP10384 8.05  LDD0318 
Proto-oncogene tyrosine-protein kinase receptor Ret (RET) LDTP02233 2.72  LDD0318 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 2.24  LDD0324 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 5.46  LDD0054 
Ras-related protein Rab-11B (RAB11B) LDTP06501 4.73  LDD0318 
Ras-related protein Ral-A (RALA) LDTP02557 2.94  LDD0318 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 5.29  LDD0054 
Ribonuclease T2 (RNASET2) LDTP00316 3.61  LDD0054 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 11.78  LDD0318 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 2.70  LDD0318 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 22.21  LDD0318 
Sialate O-acetylesterase (SIAE) LDTP12135 4.18  LDD0054 
Sialidase-1 (NEU1) LDTP10884 13.03  LDD0054 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 2.27  LDD0318 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 16.56  LDD0318 
Sulfhydryl oxidase 2 (QSOX2) LDTP07813 8.12  LDD0318 
Superoxide dismutase [Cu-Zn] (SOD1) LDTP01776 677.32  LDD0318 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 2.76  LDD0054 
Torsin-1B (TOR1B) LDTP00400 3.29  LDD0318 
Transmembrane ascorbate-dependent reductase CYB561 (CYB561) LDTP04255 2.02  LDD0054 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 2.80  LDD0054 
Ubiquitin-conjugating enzyme E2 E1 (UBE2E1) LDTP04493 5.26  LDD0318 
V-type proton ATPase 116 kDa subunit a 3 (TCIRG1) LDTP05891 2.26  LDD0324 
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⏷ Show the Full List of 120 Enzyme
108 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 20.43  LDD0318 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 2.35  LDD0318 
ADP-ribosylation factor-binding protein GGA3 (GGA3) LDTP12874 4.93  LDD0054 
Amyloid-beta precursor protein (APP) LDTP02071 157.08  LDD0318 
Anoctamin-10 (ANO10) LDTP12704 2.60  LDD0318 
Apoptosis regulator BAX (BAX) LDTP05528 3.69  LDD0324 
Bone marrow stromal antigen 2 (BST2) LDTP05631 38.73  LDD0324 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 2.69  LDD0054 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 4.64  LDD0318 
CD151 antigen (CD151) LDTP04187 5.51  LDD0318 
CD44 antigen (CD44) LDTP02823 4.36  LDD0324 
CD63 antigen (CD63) LDTP02320 30.38  LDD0318 
CD81 antigen (CD81) LDTP04849 8.50  LDD0318 
CD9 antigen (CD9) LDTP03142 25.09  LDD0318 
Chromaffin granule amine transporter (SLC18A1) LDTP04603 24.32  LDD0318 
Cochlin (COCH) LDTP00761 6.01  LDD0318 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 2.62  LDD0318 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 30.84  LDD0318 
Endophilin-B1 (SH3GLB1) LDTP13953 2.75  LDD0318 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 2.02  LDD0324 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 2.36  LDD0054 
H(+)/Cl(-) exchange transporter 6 (CLCN6) LDTP04462 3.69  LDD0318 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 16.75  LDD0318 
Integral membrane protein 2B (ITM2B) LDTP13833 4.74  LDD0318 
Integral membrane protein 2C (ITM2C) LDTP12451 9.75  LDD0318 
Integrin alpha-11 (ITGA11) LDTP13497 2.37  LDD0324 
Integrin alpha-5 (ITGA5) LDTP02295 5.53  LDD0324 
Integrin alpha-6 (ITGA6) LDTP03211 4.05  LDD0324 
Integrin alpha-V (ITGAV) LDTP02166 25.12  LDD0318 
Integrin beta-1 (ITGB1) LDTP02122 5.33  LDD0318 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 5.05  LDD0318 
Lysosome membrane protein 2 (SCARB2) LDTP06034 44.37  LDD0318 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 2.21  LDD0054 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 10.31  LDD0324 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 4.01  LDD0318 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 6.29  LDD0318 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 10.70  LDD0318 
Mitochondrial chaperone BCS1 (BCS1L) LDTP13823 2.27  LDD0318 
Mitochondrial glutamate carrier 1 (SLC25A22) LDTP12078 12.54  LDD0318 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 11.69  LDD0318 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 9.59  LDD0324 
Neuroligin-2 (NLGN2) LDTP09235 2.63  LDD0318 
Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3) LDTP03639 6.06  LDD0318 
Neutral amino acid transporter B(0) (SLC1A5) LDTP06462 4.18  LDD0318 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 20.65  LDD0318 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 177.55  LDD0318 
Osteopetrosis-associated transmembrane protein 1 (OSTM1) LDTP08327 3.50  LDD0054 
Podocalyxin (PODXL) LDTP00321 9.05  LDD0318 
Prolow-density lipoprotein receptor-related protein 1 (LRP1) LDTP05538 3.55  LDD0318 
Prosaposin (PSAP) LDTP02215 1,782.93  LDD0318 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 2.82  LDD0318 
Protein tweety homolog 3 (TTYH3) LDTP11615 9.96  LDD0318 
Proton-activated chloride channel (PACC1) LDTP12042 5.36  LDD0054 
Proton-coupled zinc antiporter SLC30A1 (SLC30A1) LDTP14274 5.62  LDD0324 
Proton-transporting V-type ATPase complex assembly regulator TMEM9 (TMEM9) LDTP12981 4.29  LDD0054 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 3.05  LDD0318 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 2.08  LDD0318 
Reticulon-1 (RTN1) LDTP06633 3.25  LDD0318 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 14.23  LDD0324 
Secretogranin-1 (CHGB) LDTP02069 18.90  LDD0318 
Secretory carrier-associated membrane protein 4 (SCAMP4) LDTP09987 7.42  LDD0318 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 2.86  LDD0054 
Sodium-dependent glucose transporter 1 (MFSD4B) LDTP17246 3.75  LDD0054 
Sodium-dependent multivitamin transporter (SLC5A6) LDTP13834 2.20  LDD0318 
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) LDTP02068 3.16  LDD0318 
Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) LDTP04624 3.49  LDD0318 
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 6.21  LDD0318 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 6.64  LDD0318 
Solute carrier family 35 member F6 (SLC35F6) LDTP08817 7.91  LDD0318 
Sortilin (SORT1) LDTP10885 2.43  LDD0054 
Sortilin-related receptor (SORL1) LDTP09838 4.41  LDD0318 
Sorting nexin-5 (SNX5) LDTP14174 5.05  LDD0318 
SPARC (SPARC) LDTP02349 3.94  LDD0318 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 6.86  LDD0318 
Synaptophysin (SYP) LDTP02266 2.85  LDD0054 
Synaptosomal-associated protein 23 (SNAP23) LDTP00198 3.70  LDD0318 
Synaptotagmin-1 (SYT1) LDTP03117 10.00  LDD0318 
Syntaxin-6 (STX6) LDTP00857 5.02  LDD0318 
Syntenin-1 (SDCBP) LDTP00310 2.03  LDD0324 
Tetraspanin-3 (TSPAN3) LDTP16813 9.86  LDD0318 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 2.48  LDD0318 
Transferrin receptor protein 1 (TFRC) LDTP01969 3.43  LDD0318 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 4.54  LDD0318 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 9.80  LDD0318 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 2.72  LDD0318 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 2.06  LDD0318 
Transmembrane emp24 domain-containing protein 1 (TMED1) LDTP05875 2.67  LDD0318 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 2.29  LDD0318 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 4.90  LDD0318 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 12.00  LDD0318 
Transmembrane protein 106B (TMEM106B) LDTP12635 20.60  LDD0318 
Transmembrane protein 192 (TMEM192) LDTP08633 5.05  LDD0318 
Transmembrane protein 199 (TMEM199) LDTP08881 29.96  LDD0318 
Transmembrane protein 87A (TMEM87A) LDTP15481 25.97  LDD0318 
Transmembrane protein 87B (TMEM87B) LDTP15756 16.17  LDD0318 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 5.17  LDD0318 
Vesicle-associated membrane protein 2 (VAMP2) LDTP05039 38.09  LDD0318 
Vesicle-associated membrane protein 3 (VAMP3) LDTP06490 4.88  LDD0318 
Vesicle-associated membrane protein 8 (VAMP8) LDTP11265 3.91  LDD0324 
Vesicular acetylcholine transporter (SLC18A3) LDTP06561 6.68  LDD0318 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 13.33  LDD0318 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 8.33  LDD0318 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 2.32  LDD0318 
Voltage-dependent calcium channel subunit alpha-2/delta-1 (CACNA2D1) LDTP04612 4.50  LDD0318 
Voltage-dependent calcium channel subunit alpha-2/delta-2 (CACNA2D2) LDTP12805 4.41  LDD0318 
VPS10 domain-containing receptor SorCS1 (SORCS1) LDTP09724 3.30  LDD0318 
Zinc transporter ZIP1 (SLC39A1) LDTP12799 8.07  LDD0318 
Zinc transporter ZIP10 (SLC39A10) LDTP13543 2.60  LDD0318 
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⏷ Show the Full List of 108 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 2.02  LDD0324 
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3 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adhesion G protein-coupled receptor L2 (ADGRL2) LDTP01622 6.27  LDD0318 
Alpha-2A adrenergic receptor (ADRA2A) LDTP02317 4.40  LDD0324 
Muscarinic acetylcholine receptor M3 (CHRM3) LDTP03045 4.98  LDD0318 
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19 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 35.79  LDD0318 
CD166 antigen (ALCAM) LDTP05973 12.59  LDD0318 
CD276 antigen (CD276) LDTP07280 17.93  LDD0318 
Cell adhesion molecule 1 (CADM1) LDTP11441 39.05  LDD0318 
Cell surface glycoprotein MUC18 (MCAM) LDTP04020 5.09  LDD0324 
Contactin-1 (CNTN1) LDTP05672 2.41  LDD0318 
Immunoglobulin superfamily containing leucine-rich repeat protein 2 (ISLR2) LDTP07712 15.07  LDD0318 
Immunoglobulin superfamily member 1 (IGSF1) LDTP08927 9.85  LDD0318 
Immunoglobulin superfamily member 3 (IGSF3) LDTP01108 4.22  LDD0318 
Insulin-like growth factor-binding protein-like 1 (IGFBPL1) LDTP15641 18.19  LDD0318 
Nectin-1 (NECTIN1) LDTP06340 22.44  LDD0318 
Netrin receptor UNC5B (UNC5B) LDTP08703 7.07  LDD0318 
Netrin receptor UNC5C (UNC5C) LDTP01520 3.18  LDD0318 
Neural cell adhesion molecule 1 (NCAM1) LDTP02666 4.44  LDD0318 
Neural cell adhesion molecule L1 (L1CAM) LDTP03624 13.72  LDD0318 
Neuronal cell adhesion molecule (NRCAM) LDTP09887 3.95  LDD0318 
Poliovirus receptor (PVR) LDTP02767 5.06  LDD0318 
Prostaglandin F2 receptor negative regulator (PTGFRN) LDTP13034 19.41  LDD0318 
Semaphorin-4C (SEMA4C) LDTP11598 8.04  LDD0318 
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⏷ Show the Full List of 19 Immunoglobulin
2 Cytokine and receptor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ciliary neurotrophic factor receptor subunit alpha (CNTFR) LDTP03377 2.14  LDD0054 
Interferon gamma receptor 1 (IFNGR1) LDTP02775 2.94  LDD0318 
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115 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 5.87  LDD0318 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 2.87  LDD0318 
Actin-related protein 2/3 complex subunit 1A (ARPC1A) LDTP15664 2.80  LDD0318 
Amyloid beta precursor like protein 1 (APLP1) LDTP04455 8.16  LDD0318 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 20.54  LDD0318 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 2.05  LDD0324 
Anthrax toxin receptor 1 (ANTXR1) LDTP12004 5.46  LDD0318 
Apolipoprotein B-100 (APOB) LDTP02013 8.47  LDD0318 
Apolipoprotein L2 (APOL2) LDTP11076 3.62  LDD0318 
Atrial natriuretic peptide receptor 3 (NPR3) LDTP02895 4.07  LDD0324 
C-type mannose receptor 2 (MRC2) LDTP13114 14.29  LDD0318 
Cadherin-13 (CDH13) LDTP04698 3.68  LDD0324 
Cadherin-2 (CDH2) LDTP02977 5.85  LDD0318 
Calmodulin-3 (CALM3) LDTP02443 16.59  LDD0318 
Calumenin (CALU) LDTP00887 5.94  LDD0318 
CD109 antigen (CD109) LDTP07760 2.39  LDD0324 
CD59 glycoprotein (CD59) LDTP02704 11.61  LDD0318 
CD99 antigen (CD99) LDTP02715 2.71  LDD0054 
Cell cycle exit and neuronal differentiation protein 1 (CEND1) LDTP15395 8.16  LDD0318 
Chromogranin-A (CHGA) LDTP02512 1,006.68  LDD0318 
Clusterin (CLU) LDTP02526 5.75  LDD0324 
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) LDTP14251 7.14  LDD0318 
Cystatin-C (CST3) LDTP01818 3.85  LDD0318 
Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) LDTP15980 4.37  LDD0318 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 5.98  LDD0318 
Desmoglein-2 (DSG2) LDTP06042 2.40  LDD0324 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 7.80  LDD0318 
Dickkopf-related protein 1 (DKK1) LDTP01457 3.21  LDD0318 
DnaJ homolog subfamily B member 11 (DNAJB11) LDTP13152 2.84  LDD0318 
DnaJ homolog subfamily C member 5 (DNAJC5) LDTP11894 5.85  LDD0318 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 2.97  LDD0318 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 2.27  LDD0318 
Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 (ELAPOR2) LDTP14398 12.06  LDD0318 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 2.23  LDD0318 
Galanin peptides (GAL) LDTP03175 2.76  LDD0054 
Galectin-3-binding protein (LGALS3BP) LDTP05558 16.83  LDD0318 
Gamma-soluble NSF attachment protein (NAPG) LDTP10969 2.30  LDD0324 
Ganglioside GM2 activator (GM2A) LDTP02927 2.76  LDD0054 
Glypican-2 (GPC2) LDTP08758 3.07  LDD0318 
Golgi apparatus protein 1 (GLG1) LDTP09920 8.38  LDD0318 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 71.99  LDD0318 
Golgi membrane protein 1 (GOLM1) LDTP09054 36.55  LDD0318 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 3.24  LDD0318 
Histone H2A type 1-J (H2AC14) LDTP10999 2.50  LDD0318 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 2.29  LDD0318 
Insulin-like growth factor-binding protein 2 (IGFBP2) LDTP02937 2.96  LDD0054 
Integrin alpha-2 (ITGA2) LDTP02893 3.06  LDD0324 
Integrin alpha-3 (ITGA3) LDTP03342 3.86  LDD0324 
Integrin beta-5 (ITGB5) LDTP02941 16.78  LDD0318 
Interleukin-17 receptor D (IL17RD) LDTP09211 2.85  LDD0318 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 2.60  LDD0324 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 20.12  LDD0318 
Large ribosomal subunit protein P2 (RPLP2) LDTP02108 2.42  LDD0318 
Large ribosomal subunit protein uL11m (MRPL11) LDTP13971 2.28  LDD0318 
Low-density lipoprotein receptor-related protein 8 (LRP8) LDTP06036 2.33  LDD0324 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 49.53  LDD0318 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 8.66  LDD0318 
Metalloproteinase inhibitor 3 (TIMP3) LDTP03773 3.22  LDD0054 
Microfibrillar-associated protein 2 (MFAP2) LDTP04650 2.26  LDD0054 
Mitochondrial fission 1 protein (FIS1) LDTP13982 4.38  LDD0318 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 2.31  LDD0318 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 29.51  LDD0318 
Myristoylated alanine-rich C-kinase substrate (MARCKS) LDTP03503 3.48  LDD0318 
Neudesin (NENF) LDTP13630 362.11  LDD0318 
Neurofilament light polypeptide (NEFL) LDTP02180 2.88  LDD0318 
Neurosecretory protein VGF (VGF) LDTP00584 31.34  LDD0318 
Nicastrin (NCSTN) LDTP09787 24.68  LDD0318 
Nucleobindin-1 (NUCB1) LDTP05375 13.01  LDD0318 
Nucleobindin-2 (NUCB2) LDTP05160 24.62  LDD0318 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 6.74  LDD0318 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 3.18  LDD0318 
Nurim (NRM) LDTP08606 5.38  LDD0318 
Perilipin-2 (PLIN2) LDTP10889 2.46  LDD0054 
Plasminogen receptor (KT) (PLGRKT) LDTP18435 3.82  LDD0318 
Plexin domain-containing protein 2 (PLXDC2) LDTP07698 3.37  LDD0324 
Prefoldin subunit 2 (PFDN2) LDTP13309 2.25  LDD0318 
Pro-neuropeptide Y (NPY) LDTP01855 62.80  LDD0318 
Prohibitin-2 (PHB2) LDTP10924 3.11  LDD0318 
ProSAAS (PCSK1N) LDTP13281 2.88  LDD0054 
Protein canopy homolog 2 (CNPY2) LDTP13841 2.94  LDD0318 
Protein delta homolog 1 (DLK1) LDTP05162 17.92  LDD0318 
Protein FAM114A2 (FAM114A2) LDTP16080 7.39  LDD0318 
Protein FAM162A (FAM162A) LDTP10056 12.56  LDD0318 
Protein GOLM2 (GOLM2) LDTP15115 38.12  LDD0318 
Protein LYRIC (MTDH) LDTP08224 2.02  LDD0318 
Protein S100-A13 (S100A13) LDTP10908 3.46  LDD0324 
Protein SET (SET) LDTP05277 9.01  LDD0318 
Rab proteins geranylgeranyltransferase component A 2 (CHML) LDTP03355 5.11  LDD0318 
Required for meiotic nuclear division protein 1 homolog (RMND1) LDTP12729 2.21  LDD0318 
Reticulocalbin-1 (RCN1) LDTP06352 12.73  LDD0318 
Reticulocalbin-2 (RCN2) LDTP06097 21.44  LDD0318 
Reticulon-3 (RTN3) LDTP01522 7.06  LDD0318 
Reticulon-4 (RTN4) LDTP12412 5.35  LDD0318 
Rho GTPase-activating protein 36 (ARHGAP36) LDTP17482 4.62  LDD0318 
Secretogranin-2 (SCG2) LDTP02661 110.09  LDD0318 
Secretogranin-3 (SCG3) LDTP09689 3,620.23  LDD0318 
Seizure 6-like protein (SEZ6L) LDTP11461 2.47  LDD0054 
Seizure 6-like protein 2 (SEZ6L2) LDTP07703 2.14  LDD0054 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 2.17  LDD0318 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 2.68  LDD0318 
Stathmin (STMN1) LDTP02869 4.51  LDD0318 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 11.45  LDD0318 
Synaptogyrin-2 (SYNGR2) LDTP00859 12.49  LDD0318 
Synaptophysin-like protein 1 (SYPL1) LDTP06557 2.40  LDD0324 
Syntaxin-12 (STX12) LDTP08389 3.13  LDD0318 
Tissue factor pathway inhibitor 2 (TFPI2) LDTP04172 4.46  LDD0054 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 2.59  LDD0054 
Transmembrane emp24 domain-containing protein 4 (TMED4) LDTP08153 20.11  LDD0318 
Trophoblast glycoprotein (TPBG) LDTP05960 7.05  LDD0318 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 4.03  LDD0318 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 2.54  LDD0318 
Tumor protein D54 (TPD52L2) LDTP00759 3.08  LDD0318 
Vang-like protein 2 (VANGL2) LDTP13560 2.17  LDD0318 
Very low-density lipoprotein receptor (VLDLR) LDTP05215 3.68  LDD0318 
Zinc finger protein ZPR1 (ZPR1) LDTP01171 2.75  LDD0318 
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⏷ Show the Full List of 115 Other

Competitor(s) Related To This Probe

Competitor ID Name Concentration Cell-system Ref
 LDCM0008  Tranylcypromine 20 uM Human endocervical adenocarcinoma cell lysate (HeLa) [1]

Full Information of The Labelling Profiles of This Probe

Quantification: Probe vs DMSO
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
LFQ
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Adrenal
Disease Model
Bone marrow neuroblastoma [ICD11: 2A00]
Model Name
Human neuroblastoma cells (SH-SY5Y)
Interaction Atlas ID
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
LFQ
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Cervix uteri
Disease Model
Endocervical adenocarcinoma [ICD-11:2C77]
Model Name
Human endocervical adenocarcinoma cell lysate (HeLa)
Interaction Atlas ID
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
LFQ
Competitor Name
Tranylcypromine
Competitor Concentration
100 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Adrenal
Disease Model
Bone marrow neuroblastoma [ICD11: 2A00]
Model Name
Human neuroblastoma cells (SH-SY5Y)
Interaction Atlas ID
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
LFQ
Competitor Name
Tranylcypromine
Competitor Concentration
20 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Cervix uteri
Disease Model
Endocervical adenocarcinoma [ICD-11:2C77]
Model Name
Human endocervical adenocarcinoma cell lysate (HeLa)
Interaction Atlas ID

References

1 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580