Details of the Target

General Information of Target

Target ID LDTP08817
Target Name Solute carrier family 35 member F6 (SLC35F6)
Gene Name SLC35F6
Gene ID 54978
Synonyms
C2orf18; Solute carrier family 35 member F6; ANT2-binding protein; ANT2BP; Transport and Golgi organization 9 homolog
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAWTKYQLFLAGLMLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFS
CLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQML
RGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGD
LLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGTEGLFGFVILSLLLVPMYYIPAGSFSG
NPRGTLEDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRT
VVIWALSLALGWEAFHALQILGFLILLIGTALYNGLHRPLLGRLSRGRPLAEESEQERLL
GGTRTPINDAS
Target Bioclass
Transporter and channel
Family
SLC35F solute transporter family
Subcellular location
Mitochondrion
Function
Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter.
Uniprot ID
Q8N357
Ensemble ID
ENST00000344420.10
HGNC ID
HGNC:26055

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FBPP2
 Probe Info  		7.91  LDD0318  [1]
YN-1
 Probe Info  		100.00  LDD0444  [2]
THZ1-DTB
 Probe Info  		C36(2.18)  LDD0461  [3]
DBIA
 Probe Info  		C36(0.43)  LDD0533  [4]
IPM
 Probe Info  		N.A.  LDD2156  [5]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [6]
Methacrolein
 Probe Info  		N.A.  LDD0218  [6]
AOyne
 Probe Info  		15.00  LDD0443  [7]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info  		N.A.  LDD0396  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C36(0.26)  LDD1093  [4]
 LDCM0215  AC10 PaTu 8988t C36(0.60)  LDD1094  [4]
 LDCM0216  AC100 HCT 116 C36(0.43)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C36(0.46)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C36(0.45)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C36(0.33)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C36(0.36)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C36(0.33)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C36(0.37)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C36(0.40)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C36(0.39)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C36(0.48)  LDD0542  [4]
 LDCM0226  AC11 PaTu 8988t C36(0.66)  LDD1105  [4]
 LDCM0227  AC110 HCT 116 C36(0.42)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C36(0.40)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C36(0.40)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C36(1.03)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C36(0.65)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C36(0.56)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C36(0.83)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C36(0.72)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C36(0.70)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C36(0.96)  LDD0553  [4]
 LDCM0237  AC12 PaTu 8988t C36(0.67)  LDD1116  [4]
 LDCM0238  AC120 HCT 116 C36(0.75)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C36(0.80)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C36(0.75)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C36(0.75)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C36(0.61)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C36(0.99)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C36(0.59)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C36(0.61)  LDD0562  [4]
 LDCM0259  AC14 PaTu 8988t C36(0.69)  LDD1138  [4]
 LDCM0263  AC143 HCT 116 C36(0.95)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C36(0.57)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C36(0.36)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C36(0.76)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C36(0.52)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C36(0.49)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C36(0.36)  LDD0586  [4]
 LDCM0270  AC15 PaTu 8988t C36(0.61)  LDD1149  [4]
 LDCM0271  AC150 HCT 116 C36(0.61)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C36(0.81)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C36(0.58)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C36(0.37)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C36(0.40)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C36(0.66)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C36(0.63)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C36(0.56)  LDD2161  [4]
 LDCM0276  AC17 HEK-293T C36(0.96)  LDD1515  [9]
 LDCM0277  AC18 HEK-293T C36(0.90)  LDD1516  [9]
 LDCM0278  AC19 HEK-293T C36(1.10)  LDD1517  [9]
 LDCM0279  AC2 PaTu 8988t C36(0.28)  LDD1158  [4]
 LDCM0280  AC20 HEK-293T C36(0.98)  LDD1519  [9]
 LDCM0281  AC21 HEK-293T C36(0.94)  LDD1520  [9]
 LDCM0282  AC22 HEK-293T C36(1.04)  LDD1521  [9]
 LDCM0283  AC23 HEK-293T C36(1.02)  LDD1522  [9]
 LDCM0284  AC24 HEK-293T C36(0.98)  LDD1523  [9]
 LDCM0285  AC25 HCT 116 C36(0.41)  LDD0602  [4]
 LDCM0286  AC26 HCT 116 C36(0.50)  LDD0603  [4]
 LDCM0287  AC27 HCT 116 C36(0.44)  LDD0604  [4]
 LDCM0288  AC28 HCT 116 C36(0.49)  LDD0605  [4]
 LDCM0289  AC29 HCT 116 C36(0.46)  LDD0606  [4]
 LDCM0290  AC3 PaTu 8988t C36(0.20)  LDD1169  [4]
 LDCM0291  AC30 HCT 116 C36(0.48)  LDD0608  [4]
 LDCM0292  AC31 HCT 116 C36(0.34)  LDD0609  [4]
 LDCM0293  AC32 HCT 116 C36(0.41)  LDD0610  [4]
 LDCM0294  AC33 HCT 116 C36(0.36)  LDD0611  [4]
 LDCM0295  AC34 HCT 116 C36(0.31)  LDD0612  [4]
 LDCM0296  AC35 HCT 116 C36(1.10)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C36(1.05)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C36(1.21)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C36(1.27)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C36(1.19)  LDD0617  [4]
 LDCM0301  AC4 PaTu 8988t C36(0.26)  LDD1180  [4]
 LDCM0302  AC40 HCT 116 C36(1.18)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C36(1.05)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C36(1.16)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C36(1.22)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C36(1.14)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C36(1.07)  LDD0624  [4]
 LDCM0308  AC46 HCT 116 C36(0.98)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C36(1.15)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C36(0.89)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C36(1.10)  LDD0628  [4]
 LDCM0312  AC5 PaTu 8988t C36(0.24)  LDD1191  [4]
 LDCM0313  AC50 HCT 116 C36(0.97)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C36(1.72)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C36(1.36)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C36(0.87)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C36(1.12)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C36(1.01)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C36(0.89)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C36(0.84)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C36(0.58)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C36(0.56)  LDD0639  [4]
 LDCM0323  AC6 PaTu 8988t C36(0.78)  LDD1202  [4]
 LDCM0324  AC60 HCT 116 C36(0.46)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C36(0.56)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C36(0.54)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C36(0.71)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C36(0.64)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C36(0.78)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C36(0.78)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C36(0.49)  LDD0648  [4]
 LDCM0332  AC68 HCT 116 C36(1.16)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C36(1.16)  LDD0650  [4]
 LDCM0334  AC7 PaTu 8988t C36(0.91)  LDD1213  [4]
 LDCM0335  AC70 HCT 116 C36(0.87)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C36(1.65)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C36(1.50)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C36(0.92)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C36(0.97)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C36(0.91)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C36(0.87)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C36(1.10)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C36(1.06)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C36(1.26)  LDD0661  [4]
 LDCM0345  AC8 PaTu 8988t C36(0.74)  LDD1224  [4]
 LDCM0346  AC80 HCT 116 C36(0.97)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C36(0.97)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C36(0.74)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C36(0.56)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C36(0.55)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C36(0.72)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C36(0.77)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C36(0.75)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C36(0.66)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C36(0.57)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C36(1.11)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C36(0.53)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C36(0.60)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C36(0.66)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C36(0.71)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C36(0.66)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C36(0.59)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C36(0.62)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C36(0.20)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C36(0.58)  LDD0683  [4]
 LDCM0248  AKOS034007472 PaTu 8988t C36(0.62)  LDD1127  [4]
 LDCM0356  AKOS034007680 PaTu 8988t C36(0.64)  LDD1235  [4]
 LDCM0275  AKOS034007705 PaTu 8988t C36(0.64)  LDD1154  [4]
 LDCM0367  CL1 PaTu 8988t C36(1.24)  LDD1246  [4]
 LDCM0368  CL10 PaTu 8988t C36(0.80)  LDD1247  [4]
 LDCM0369  CL100 PaTu 8988t C36(0.22)  LDD1248  [4]
 LDCM0370  CL101 PaTu 8988t C36(0.77)  LDD1249  [4]
 LDCM0371  CL102 PaTu 8988t C36(0.73)  LDD1250  [4]
 LDCM0372  CL103 PaTu 8988t C36(0.66)  LDD1251  [4]
 LDCM0373  CL104 PaTu 8988t C36(0.65)  LDD1252  [4]
 LDCM0374  CL105 HEK-293T C36(0.98)  LDD1578  [9]
 LDCM0375  CL106 HEK-293T C36(0.95)  LDD1579  [9]
 LDCM0376  CL107 HEK-293T C36(1.00)  LDD1580  [9]
 LDCM0377  CL108 HEK-293T C36(1.05)  LDD1581  [9]
 LDCM0378  CL109 HEK-293T C36(0.98)  LDD1582  [9]
 LDCM0379  CL11 PaTu 8988t C36(0.81)  LDD1258  [4]
 LDCM0380  CL110 HEK-293T C36(1.18)  LDD1584  [9]
 LDCM0381  CL111 HEK-293T C36(1.12)  LDD1585  [9]
 LDCM0382  CL112 HCT 116 C36(0.51)  LDD0699  [4]
 LDCM0383  CL113 HCT 116 C36(0.52)  LDD0700  [4]
 LDCM0384  CL114 HCT 116 C36(0.48)  LDD0701  [4]
 LDCM0385  CL115 HCT 116 C36(0.40)  LDD0702  [4]
 LDCM0386  CL116 HCT 116 C36(0.60)  LDD0703  [4]
 LDCM0387  CL117 HCT 116 C36(1.12)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C36(1.37)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C36(1.21)  LDD0706  [4]
 LDCM0390  CL12 PaTu 8988t C36(0.54)  LDD1269  [4]
 LDCM0391  CL120 HCT 116 C36(1.17)  LDD0708  [4]
 LDCM0392  CL121 HCT 116 C36(1.20)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C36(1.28)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C36(1.14)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C36(1.08)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C36(1.10)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C36(0.57)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C36(0.76)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C36(0.58)  LDD0716  [4]
 LDCM0400  CL13 PaTu 8988t C36(0.61)  LDD1279  [4]
 LDCM0401  CL14 PaTu 8988t C36(0.58)  LDD1280  [4]
 LDCM0402  CL15 PaTu 8988t C36(0.55)  LDD1281  [4]
 LDCM0403  CL16 PaTu 8988t C36(0.79)  LDD1282  [4]
 LDCM0404  CL17 PaTu 8988t C36(0.79)  LDD1283  [4]
 LDCM0405  CL18 PaTu 8988t C36(0.72)  LDD1284  [4]
 LDCM0406  CL19 PaTu 8988t C36(0.67)  LDD1285  [4]
 LDCM0407  CL2 PaTu 8988t C36(0.47)  LDD1286  [4]
 LDCM0408  CL20 PaTu 8988t C36(0.69)  LDD1287  [4]
 LDCM0409  CL21 PaTu 8988t C36(0.71)  LDD1288  [4]
 LDCM0410  CL22 PaTu 8988t C36(0.77)  LDD1289  [4]
 LDCM0411  CL23 PaTu 8988t C36(0.77)  LDD1290  [4]
 LDCM0412  CL24 PaTu 8988t C36(0.86)  LDD1291  [4]
 LDCM0413  CL25 PaTu 8988t C36(0.77)  LDD1292  [4]
 LDCM0414  CL26 PaTu 8988t C36(0.78)  LDD1293  [4]
 LDCM0415  CL27 PaTu 8988t C36(0.82)  LDD1294  [4]
 LDCM0416  CL28 PaTu 8988t C36(0.77)  LDD1295  [4]
 LDCM0417  CL29 PaTu 8988t C36(0.71)  LDD1296  [4]
 LDCM0418  CL3 PaTu 8988t C36(0.52)  LDD1297  [4]
 LDCM0419  CL30 PaTu 8988t C36(0.79)  LDD1298  [4]
 LDCM0420  CL31 HCT 116 C36(0.58)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C36(0.60)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C36(0.47)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C36(0.42)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C36(0.63)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C36(0.64)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C36(0.50)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C36(0.50)  LDD0745  [4]
 LDCM0429  CL4 PaTu 8988t C36(0.90)  LDD1308  [4]
 LDCM0430  CL40 HCT 116 C36(0.42)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C36(0.51)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C36(0.39)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C36(0.47)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C36(0.60)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C36(0.43)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C36(1.29)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C36(1.16)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C36(1.06)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C36(0.91)  LDD0756  [4]
 LDCM0440  CL5 PaTu 8988t C36(0.57)  LDD1319  [4]
 LDCM0441  CL50 HCT 116 C36(1.05)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C36(1.38)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C36(1.23)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C36(0.97)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C36(1.04)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C36(1.17)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C36(0.89)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C36(1.38)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C36(1.25)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C36(1.10)  LDD0767  [4]
 LDCM0451  CL6 PaTu 8988t C36(0.57)  LDD1330  [4]
 LDCM0452  CL60 HCT 116 C36(1.13)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C36(0.96)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C36(1.56)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C36(1.16)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C36(1.11)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C36(1.39)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C36(0.93)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C36(1.11)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C36(1.10)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C36(1.60)  LDD0778  [4]
 LDCM0462  CL7 PaTu 8988t C36(0.67)  LDD1341  [4]
 LDCM0463  CL70 HCT 116 C36(1.04)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C36(1.44)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C36(1.31)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C36(1.43)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C36(1.07)  LDD0784  [4]
 LDCM0469  CL76 HEK-293T C36(0.96)  LDD1672  [9]
 LDCM0470  CL77 HEK-293T C36(1.07)  LDD1673  [9]
 LDCM0471  CL78 HEK-293T C36(1.01)  LDD1674  [9]
 LDCM0472  CL79 HEK-293T C36(0.97)  LDD1675  [9]
 LDCM0473  CL8 PaTu 8988t C36(0.64)  LDD1352  [4]
 LDCM0474  CL80 HEK-293T C36(1.04)  LDD1677  [9]
 LDCM0475  CL81 HEK-293T C36(0.99)  LDD1678  [9]
 LDCM0476  CL82 HEK-293T C36(1.10)  LDD1679  [9]
 LDCM0477  CL83 HEK-293T C36(1.21)  LDD1680  [9]
 LDCM0478  CL84 HEK-293T C36(1.34)  LDD1681  [9]
 LDCM0479  CL85 HEK-293T C36(1.09)  LDD1682  [9]
 LDCM0480  CL86 HEK-293T C36(1.05)  LDD1683  [9]
 LDCM0481  CL87 HEK-293T C36(1.01)  LDD1684  [9]
 LDCM0482  CL88 HEK-293T C36(1.02)  LDD1685  [9]
 LDCM0483  CL89 HEK-293T C36(1.01)  LDD1686  [9]
 LDCM0484  CL9 PaTu 8988t C36(0.56)  LDD1363  [4]
 LDCM0485  CL90 HEK-293T C36(1.39)  LDD1688  [9]
 LDCM0486  CL91 PaTu 8988t C36(0.37)  LDD1365  [4]
 LDCM0487  CL92 PaTu 8988t C36(0.46)  LDD1366  [4]
 LDCM0488  CL93 PaTu 8988t C36(0.28)  LDD1367  [4]
 LDCM0489  CL94 PaTu 8988t C36(0.33)  LDD1368  [4]
 LDCM0490  CL95 PaTu 8988t C36(0.23)  LDD1369  [4]
 LDCM0491  CL96 PaTu 8988t C36(0.31)  LDD1370  [4]
 LDCM0492  CL97 PaTu 8988t C36(0.34)  LDD1371  [4]
 LDCM0493  CL98 PaTu 8988t C36(0.25)  LDD1372  [4]
 LDCM0494  CL99 PaTu 8988t C36(0.31)  LDD1373  [4]
 LDCM0495  E2913 HEK-293T C36(0.98)  LDD1698  [9]
 LDCM0468  Fragment33 HCT 116 C36(1.49)  LDD0785  [4]
 LDCM0427  Fragment51 HCT 116 C36(0.44)  LDD0744  [4]
 LDCM0022  KB02 HEK-293T C36(1.00)  LDD1492  [9]
 LDCM0023  KB03 HEK-293T C36(0.92)  LDD1497  [9]
 LDCM0024  KB05 HMCB C36(3.85)  LDD3312  [10]
 LDCM0178  THZ531 HeLa S3 C36(2.18)  LDD0461  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ceramide synthase 4 (CERS4) . Q9HA82
Transporter and channel
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Gap junction alpha-8 protein (GJA8) Connexin family P48165
Folate receptor alpha (FOLR1) Folate receptor family P15328
Aquaporin-6 (AQP6) MIP/aquaporin (TC 1.A.8) family Q13520
ADP/ATP translocase 2 (SLC25A5) Mitochondrial carrier (TC 2.A.29) family P05141
Transmembrane protein 14B (TMEM14B) TMEM14 family Q9NUH8
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable G-protein coupled receptor 152 (GPR152) G-protein coupled receptor 1 family Q8TDT2
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) Tim17/Tim22/Tim23 family Q9NPL8

References

1 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580
2 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
3 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
6 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840