Details of the Target
General Information of Target
| Target ID | LDTP08758 | |||||
|---|---|---|---|---|---|---|
| Target Name | Glypican-2 (GPC2) | |||||
| Gene Name | GPC2 | |||||
| Gene ID | 221914 | |||||
| Synonyms |
Glypican-2 [Cleaved into: Secreted glypican-2] |
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| 3D Structure | ||||||
| Sequence |
MSALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLR
VCPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQH SLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHP QYSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSE ALKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRGLEPDWGNYLDGL LILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAP PPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAA DASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATAR MKTAALGHDLDGQDADEDASGSGGGQQYADDWMAGAVAPPARPPRPPYPPRRDGSGGKGG GGSARYNQGRSRSGGASIGFHTQTILILSLSALALLGPR |
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| Target Bioclass |
Other
|
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| Family |
Glypican family
|
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| Subcellular location |
Secreted, extracellular space; Cell membrane
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| Function | Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
FBPP2 Probe Info |
 |
3.07 | LDD0318 | [1] | |
|
DBIA Probe Info |
 |
C32(3.41) | LDD2275 | [2] | |
|
NAIA_5 Probe Info |
 |
C260(50.00) | LDD2228 | [3] | |
Competitor(s) Related to This Target
References