Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name FBPP2  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
LFQ
Competitor Name Tranylcypromine  Competitor Info 
Competitor Concentration 20 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cell lysate (HeLa)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02217  Procathepsin L (CTSL) 3.2
 LDTP02799  N-acetylglucosamine-6-sulfatase (GNS) 2.6
 LDTP02883  Alpha-N-acetylgalactosaminidase (NAGA) 2.4
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 2.4
 LDTP02141  Alpha-galactosidase A (GLA) 2.2
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 2.3

References

1 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580