Details of the Target

General Information of Target

Target ID LDTP11140
Target Name Peroxiredoxin-like 2A (PRXL2A)
Gene Name PRXL2A
Gene ID 84293
Synonyms
C10orf58; FAM213A; PAMM; Peroxiredoxin-like 2A; Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; Protein PAMM; Redox-regulatory protein FAM213A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSEAYFRVESGALGPEENFLSLDDILMSHEKLPVRTETAMPRLGAFFLERSAGAETDNAV
PQGSKLELPLWLAKGLFDNKRRILSVELPKIYQEGWRTVFSADPNVVDLHKMGPHFYGFG
SQLLHFDSPENADISQSLLQTFIGRFRRIMDSSQNAYNEDTSALVARLDEMERGLFQTGQ
KGLNDFQCWEKGQASQITASNLVQNYKKRKFTDMED
Target Bioclass
Other
Family
Peroxiredoxin-like PRXL2 family, PRXL2A subfamily
Subcellular location
Cytoplasm
Function
Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.
Uniprot ID
Q9BRX8
Ensemble ID
ENST00000372181.1
HGNC ID
HGNC:28651
ChEMBL ID
CHEMBL3879824

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
DU4475 SNV: p.V186L .
Ishikawa (Heraklio) 02 ER SNV: p.A26T .
RKO Deletion: p.A24LfsTer29 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 17 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
EN219-alkyne
 Probe Info  		4.85  LDD0297  [1]
CHEMBL5175495
 Probe Info  		16.09  LDD0196  [2]
C-Sul
 Probe Info  		2.30  LDD0066  [3]
FBP2
 Probe Info  		3.84  LDD0317  [4]
YN-1
 Probe Info  		100.00  LDD0444  [5]
YN-4
 Probe Info  		100.00  LDD0445  [5]
STPyne
 Probe Info  		K122(10.00)  LDD0277  [6]
CCW36
 Probe Info  		10.24  LDD2215  [7]
P21
 Probe Info  		2.53  LDD0408  [8]
BTD
 Probe Info  		C85(1.09)  LDD2092  [9]
Johansson_61
 Probe Info  		_(20.00)  LDD1485  [10]
YY4-yne
 Probe Info  		2.51  LDD0400  [11]
IA-alkyne
 Probe Info  		C85(20.00)  LDD1704  [12]
DBIA
 Probe Info  		C85(3.72)  LDD0078  [13]
WYneN
 Probe Info  		N.A.  LDD0021  [14]
IPM
 Probe Info  		N.A.  LDD0005  [14]
Phosphinate-6
 Probe Info  		C85(0.00); C88(0.00)  LDD0018  [15]
PAL-AfBPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C027
 Probe Info  		6.45  LDD1733  [16]
C040
 Probe Info  		8.69  LDD1740  [16]
C094
 Probe Info  		23.10  LDD1785  [16]
C163
 Probe Info  		13.36  LDD1843  [16]
C235
 Probe Info  		20.25  LDD1908  [16]
C299
 Probe Info  		5.70  LDD1968  [16]
C362
 Probe Info  		37.27  LDD2023  [16]
C364
 Probe Info  		22.01  LDD2025  [16]
FFF probe11
 Probe Info  		14.01  LDD0471  [17]
JN0003
 Probe Info  		13.29  LDD0469  [17]
A-DA
 Probe Info  		2.26  LDD0145  [18]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C85(0.89)  LDD2142  [9]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C85(1.52)  LDD2112  [9]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C85(1.06)  LDD2103  [9]
 LDCM0214  AC1 HEK-293T C85(2.61)  LDD0812  [13]
 LDCM0216  AC100 HEK-293T C85(0.78)  LDD0814  [13]
 LDCM0217  AC101 HEK-293T C85(0.92)  LDD0815  [13]
 LDCM0218  AC102 HEK-293T C85(0.92)  LDD0816  [13]
 LDCM0219  AC103 HEK-293T C85(1.19)  LDD0817  [13]
 LDCM0220  AC104 HEK-293T C85(0.92)  LDD0818  [13]
 LDCM0221  AC105 HEK-293T C85(1.01)  LDD0819  [13]
 LDCM0222  AC106 HEK-293T C85(0.96)  LDD0820  [13]
 LDCM0223  AC107 HEK-293T C85(0.79)  LDD0821  [13]
 LDCM0224  AC108 HEK-293T C85(0.95)  LDD0822  [13]
 LDCM0225  AC109 HEK-293T C85(1.49)  LDD0823  [13]
 LDCM0227  AC110 HEK-293T C85(1.03)  LDD0825  [13]
 LDCM0228  AC111 HEK-293T C85(1.58)  LDD0826  [13]
 LDCM0229  AC112 HEK-293T C85(0.85)  LDD0827  [13]
 LDCM0237  AC12 HEK-293T C85(1.01)  LDD1510  [19]
 LDCM0263  AC143 HEK-293T C85(1.06)  LDD0861  [13]
 LDCM0264  AC144 HEK-293T C85(1.06)  LDD0862  [13]
 LDCM0265  AC145 HEK-293T C85(1.32)  LDD0863  [13]
 LDCM0266  AC146 HEK-293T C85(1.61)  LDD0864  [13]
 LDCM0267  AC147 HEK-293T C85(1.27)  LDD0865  [13]
 LDCM0268  AC148 HEK-293T C85(2.04)  LDD0866  [13]
 LDCM0269  AC149 HEK-293T C85(0.94)  LDD0867  [13]
 LDCM0271  AC150 HEK-293T C85(1.06)  LDD0869  [13]
 LDCM0272  AC151 HEK-293T C85(1.18)  LDD0870  [13]
 LDCM0273  AC152 HEK-293T C85(0.86)  LDD0871  [13]
 LDCM0274  AC153 HEK-293T C85(1.34)  LDD0872  [13]
 LDCM0621  AC154 HEK-293T C85(1.10)  LDD2162  [13]
 LDCM0622  AC155 HEK-293T C85(1.16)  LDD2163  [13]
 LDCM0623  AC156 HEK-293T C85(1.13)  LDD2164  [13]
 LDCM0624  AC157 HEK-293T C85(0.88)  LDD2165  [13]
 LDCM0276  AC17 HEK-293T C85(1.60)  LDD0874  [13]
 LDCM0277  AC18 HEK-293T C85(1.67)  LDD0875  [13]
 LDCM0278  AC19 HEK-293T C85(1.36)  LDD0876  [13]
 LDCM0279  AC2 HEK-293T C85(1.22)  LDD0877  [13]
 LDCM0280  AC20 HEK-293T C85(1.23)  LDD0878  [13]
 LDCM0281  AC21 HEK-293T C85(5.52)  LDD0879  [13]
 LDCM0282  AC22 HEK-293T C85(1.03)  LDD0880  [13]
 LDCM0283  AC23 HEK-293T C85(3.11)  LDD0881  [13]
 LDCM0284  AC24 HEK-293T C85(1.12)  LDD0882  [13]
 LDCM0288  AC28 HEK-293T C85(1.00)  LDD1527  [19]
 LDCM0290  AC3 HEK-293T C85(1.82)  LDD0888  [13]
 LDCM0296  AC35 HEK-293T C85(1.16)  LDD0894  [13]
 LDCM0297  AC36 HEK-293T C85(1.08)  LDD0895  [13]
 LDCM0298  AC37 HEK-293T C85(1.10)  LDD0896  [13]
 LDCM0299  AC38 HEK-293T C85(1.53)  LDD0897  [13]
 LDCM0300  AC39 HEK-293T C85(1.12)  LDD0898  [13]
 LDCM0301  AC4 HEK-293T C85(0.99)  LDD0899  [13]
 LDCM0302  AC40 HEK-293T C85(2.72)  LDD0900  [13]
 LDCM0303  AC41 HEK-293T C85(1.21)  LDD0901  [13]
 LDCM0304  AC42 HEK-293T C85(2.03)  LDD0902  [13]
 LDCM0305  AC43 HEK-293T C85(1.15)  LDD0903  [13]
 LDCM0306  AC44 HEK-293T C85(1.25)  LDD0904  [13]
 LDCM0307  AC45 HEK-293T C85(1.14)  LDD0905  [13]
 LDCM0312  AC5 HEK-293T C85(1.38)  LDD0910  [13]
 LDCM0315  AC52 HEK-293T C85(0.95)  LDD1554  [19]
 LDCM0320  AC57 HEK-293T C85(9.07)  LDD0918  [13]
 LDCM0321  AC58 HEK-293T C85(1.17)  LDD0919  [13]
 LDCM0322  AC59 HEK-293T C85(7.04)  LDD0920  [13]
 LDCM0324  AC60 HEK-293T C85(1.51)  LDD0922  [13]
 LDCM0325  AC61 HEK-293T C85(0.97)  LDD0923  [13]
 LDCM0326  AC62 HEK-293T C85(1.54)  LDD0924  [13]
 LDCM0327  AC63 HEK-293T C85(1.53)  LDD0925  [13]
 LDCM0328  AC64 HEK-293T C85(1.12)  LDD0926  [13]
 LDCM0329  AC65 HEK-293T C85(1.06)  LDD0927  [13]
 LDCM0330  AC66 HEK-293T C85(0.97)  LDD0928  [13]
 LDCM0331  AC67 HEK-293T C85(0.95)  LDD0929  [13]
 LDCM0365  AC98 HEK-293T C85(4.84)  LDD0963  [13]
 LDCM0366  AC99 HEK-293T C85(0.91)  LDD0964  [13]
 LDCM0020  ARS-1620 HCC44 C85(3.72)  LDD0078  [13]
 LDCM0631  CCW16 231MFP 10.24  LDD2215  [7]
 LDCM0367  CL1 HEK-293T C85(10.00)  LDD0965  [13]
 LDCM0368  CL10 HEK-293T C85(5.43)  LDD0966  [13]
 LDCM0369  CL100 HEK-293T C85(3.07)  LDD0967  [13]
 LDCM0374  CL105 HEK-293T C85(6.58)  LDD0972  [13]
 LDCM0375  CL106 HEK-293T C85(10.00)  LDD0973  [13]
 LDCM0376  CL107 HEK-293T C85(1.32)  LDD0974  [13]
 LDCM0377  CL108 HEK-293T C85(1.33)  LDD0975  [13]
 LDCM0378  CL109 HEK-293T C85(7.07)  LDD0976  [13]
 LDCM0379  CL11 HEK-293T C85(2.60)  LDD0977  [13]
 LDCM0380  CL110 HEK-293T C85(8.24)  LDD0978  [13]
 LDCM0381  CL111 HEK-293T C85(8.18)  LDD0979  [13]
 LDCM0387  CL117 HEK-293T C85(1.30)  LDD0985  [13]
 LDCM0388  CL118 HEK-293T C85(2.58)  LDD0986  [13]
 LDCM0389  CL119 HEK-293T C85(1.17)  LDD0987  [13]
 LDCM0390  CL12 HEK-293T C85(15.70)  LDD0988  [13]
 LDCM0391  CL120 HEK-293T C85(1.26)  LDD0989  [13]
 LDCM0396  CL125 HEK-293T C85(3.94)  LDD0994  [13]
 LDCM0397  CL126 HEK-293T C85(2.20)  LDD0995  [13]
 LDCM0398  CL127 HEK-293T C85(0.98)  LDD0996  [13]
 LDCM0399  CL128 HEK-293T C85(1.73)  LDD0997  [13]
 LDCM0400  CL13 HEK-293T C85(3.70)  LDD0998  [13]
 LDCM0401  CL14 HEK-293T C85(1.09)  LDD0999  [13]
 LDCM0402  CL15 HEK-293T C85(12.60)  LDD1000  [13]
 LDCM0403  CL16 HEK-293T C85(0.87)  LDD1001  [13]
 LDCM0404  CL17 HEK-293T C85(3.89)  LDD1002  [13]
 LDCM0405  CL18 HEK-293T C85(3.06)  LDD1003  [13]
 LDCM0406  CL19 HEK-293T C85(2.74)  LDD1004  [13]
 LDCM0407  CL2 HEK-293T C85(1.29)  LDD1005  [13]
 LDCM0408  CL20 HEK-293T C85(1.19)  LDD1006  [13]
 LDCM0409  CL21 HEK-293T C85(1.96)  LDD1007  [13]
 LDCM0410  CL22 HEK-293T C85(1.46)  LDD1008  [13]
 LDCM0411  CL23 HEK-293T C85(0.98)  LDD1009  [13]
 LDCM0412  CL24 HEK-293T C85(2.15)  LDD1010  [13]
 LDCM0413  CL25 HEK-293T C85(1.77)  LDD1011  [13]
 LDCM0414  CL26 HEK-293T C85(3.04)  LDD1012  [13]
 LDCM0415  CL27 HEK-293T C85(2.85)  LDD1013  [13]
 LDCM0416  CL28 HEK-293T C85(0.96)  LDD1014  [13]
 LDCM0417  CL29 HEK-293T C85(1.01)  LDD1015  [13]
 LDCM0418  CL3 HEK-293T C85(11.80)  LDD1016  [13]
 LDCM0419  CL30 HEK-293T C85(0.97)  LDD1017  [13]
 LDCM0420  CL31 HEK-293T C85(1.10)  LDD1018  [13]
 LDCM0421  CL32 HEK-293T C85(4.04)  LDD1019  [13]
 LDCM0422  CL33 HEK-293T C85(2.32)  LDD1020  [13]
 LDCM0423  CL34 HEK-293T C85(1.86)  LDD1021  [13]
 LDCM0424  CL35 HEK-293T C85(3.78)  LDD1022  [13]
 LDCM0425  CL36 HEK-293T C85(3.92)  LDD1023  [13]
 LDCM0426  CL37 HEK-293T C85(4.38)  LDD1024  [13]
 LDCM0428  CL39 HEK-293T C85(2.26)  LDD1026  [13]
 LDCM0429  CL4 HEK-293T C85(8.48)  LDD1027  [13]
 LDCM0430  CL40 HEK-293T C85(1.39)  LDD1028  [13]
 LDCM0431  CL41 HEK-293T C85(2.55)  LDD1029  [13]
 LDCM0432  CL42 HEK-293T C85(1.33)  LDD1030  [13]
 LDCM0433  CL43 HEK-293T C85(1.15)  LDD1031  [13]
 LDCM0434  CL44 HEK-293T C85(3.60)  LDD1032  [13]
 LDCM0435  CL45 HEK-293T C85(3.61)  LDD1033  [13]
 LDCM0440  CL5 HEK-293T C85(1.49)  LDD1038  [13]
 LDCM0447  CL56 HEK-293T C85(1.15)  LDD1650  [19]
 LDCM0451  CL6 HEK-293T C85(20.00)  LDD1049  [13]
 LDCM0460  CL68 HEK-293T C85(1.03)  LDD1663  [19]
 LDCM0462  CL7 HEK-293T C85(1.89)  LDD1060  [13]
 LDCM0473  CL8 HEK-293T C85(1.75)  LDD1676  [19]
 LDCM0474  CL80 HEK-293T C85(0.98)  LDD1677  [19]
 LDCM0486  CL91 HEK-293T C85(1.18)  LDD1084  [13]
 LDCM0487  CL92 HEK-293T C85(1.72)  LDD1085  [13]
 LDCM0488  CL93 HEK-293T C85(2.93)  LDD1086  [13]
 LDCM0489  CL94 HEK-293T C85(1.91)  LDD1087  [13]
 LDCM0490  CL95 HEK-293T C85(2.82)  LDD1088  [13]
 LDCM0491  CL96 HEK-293T C85(2.75)  LDD1089  [13]
 LDCM0492  CL97 HEK-293T C85(2.58)  LDD1090  [13]
 LDCM0493  CL98 HEK-293T C85(2.44)  LDD1091  [13]
 LDCM0494  CL99 HEK-293T C85(2.54)  LDD1092  [13]
 LDCM0100  EN219 231MFP 4.90  LDD0298  [1]
 LDCM0427  Fragment51 HEK-293T C85(1.12)  LDD1025  [13]
 LDCM0616  Fragment61 Jurkat _(20.00)  LDD1489  [10]
 LDCM0615  Fragment63-R Jurkat _(15.97)  LDD1487  [10]
 LDCM0569  Fragment7 Jurkat _(20.00)  LDD1485  [10]
 LDCM0022  KB02 HEK-293T C88(0.51); C85(0.25); C88(0.25)  LDD1492  [19]
 LDCM0023  KB03 HEK-293T C88(1.14); C85(0.94); C88(0.94)  LDD1497  [19]
 LDCM0024  KB05 HEK-293T C88(1.01); C85(0.91); C88(0.91)  LDD1502  [19]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C85(1.63)  LDD2102  [9]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C85(1.09)  LDD2092  [9]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C85(0.98)  LDD2093  [9]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C85(1.09)  LDD2094  [9]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C85(1.25)  LDD2098  [9]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C85(0.75)  LDD2104  [9]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C85(2.17)  LDD2106  [9]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C88(0.17)  LDD2109  [9]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C85(3.58)  LDD2122  [9]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C85(0.45)  LDD2123  [9]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C85(1.45)  LDD2135  [9]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C88(0.88)  LDD2137  [9]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C85(0.63)  LDD2141  [9]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C85(4.61)  LDD2145  [9]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C85(1.10)  LDD2146  [9]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C85(1.25)  LDD2151  [9]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C85(2.57)  LDD2153  [9]
 LDCM0158  P27 BxPC-3 2.53  LDD0408  [8]
 LDCM0084  Ro 48-8071 A-549 2.26  LDD0145  [18]
 LDCM0154  YY4 T cell 2.51  LDD0400  [11]

References

1 Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function. Cell Chem Biol. 2021 Apr 15;28(4):559-566.e15. doi: 10.1016/j.chembiol.2021.01.005. Epub 2021 Jan 28.
2 Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.
3 Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells. Anal Chem. 2022 Mar 15;94(10):4366-4372. doi: 10.1021/acs.analchem.1c05129. Epub 2022 Mar 4.
4 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580
5 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
6 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
7 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
8 Integrated phenotypic screening and activity-based protein profiling to reveal potential therapy targets of pancreatic cancer. Chem Commun (Camb). 2019 Jan 31;55(11):1596-1599. doi: 10.1039/c8cc08753a.
9 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
10 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
11 A Chemical Proteomic Probe for the Mitochondrial Pyruvate Carrier Complex. Angew Chem Int Ed Engl. 2020 Mar 2;59(10):3896-3899. doi: 10.1002/anie.201914391. Epub 2020 Feb 11.
12 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
13 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
14 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
15 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
16 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
17 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
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Mass spectrometry data entry: PXD044402