Details of the Probe

General Information of Probe

Probe ID
LDPC0121
Probe Name
A-DA
Synonyms
SCHEMBL18092677
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 381.6
Lipid-water partition coefficient (xlogp) 5.6
Rotatable Bond Count (rotbonds) 16
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C24H35N3O
IUPAC Name
(5Z,8Z,11Z,14Z)-N-[2-(3-methyldiazirin-3-yl)ethyl]icosa-5,8,11,14-tetraen-19-ynamide
Canonical SMILES
CC1(N=N1)CCNC(=O)CCCC=CCC=CCC=CCC=CCCCC#C
InChI
InChI=1S/C24H35N3O/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23(28)25-22-21-24(2)26-27-24/h1,7-8,10-11,13-14,16-17H,4-6,9,12,15,18-22H2,2H3,(H,25,28)/b8-7-,11-10-,14-13-,17-16-
InChIKey
VCYPOIHJBWLYDA-ZKWNWVNESA-N

The Probe Interaction Atlas

Target(s) List of this Probe

95 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) LDTP09542 20.00  LDD0143 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 2.08  LDD0145 
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (COQ5) LDTP06988 3.43  LDD0145 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 16.03  LDD0144 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 12.90  LDD0145 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 2.10  LDD0143 
ADP-dependent glucokinase (ADPGK) LDTP11127 2.09  LDD0145 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 2.00  LDD0142 
Aldehyde dehydrogenase family 3 member B1 (ALDH3B1) LDTP04036 2.11  LDD0145 
Aldo-keto reductase family 1 member C3 (AKR1C3) LDTP03976 2.17  LDD0140 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 2.31  LDD0145 
Arylsulfatase L (ARSL) LDTP04453 2.29  LDD0142 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 3.60  LDD0331 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 4.38  LDD0142 
Catechol O-methyltransferase (COMT) LDTP03145 2.23  LDD0145 
Cathepsin D (CTSD) LDTP02198 2.05  LDD0145 
Ceramide glucosyltransferase (UGCG) LDTP06617 2.88  LDD0145 
Ceramide synthase 2 (CERS2) LDTP10329 2.52  LDD0145 
Ceramide synthase 6 (CERS6) LDTP07766 2.72  LDD0144 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 2.20  LDD0145 
Choline dehydrogenase, mitochondrial (CHDH) LDTP15505 3.25  LDD0331 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 2.51  LDD0145 
Cytochrome b5 (CYB5A) LDTP01763 2.17  LDD0141 
Cytochrome b5 type B (CYB5B) LDTP00697 2.09  LDD0143 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.68  LDD0143 
Dehydrogenase/reductase SDR family member on chromosome X (DHRSX) LDTP08900 3.74  LDD0143 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 2.10  LDD0143 
Delta(24)-sterol reductase (DHCR24) LDTP06375 2.32  LDD0142 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 5.13  LDD0145 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 2.01  LDD0145 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 2.05  LDD0143 
Epoxide hydrolase 1 (EPHX1) LDTP02175 2.45  LDD0143 
Estradiol 17-beta-dehydrogenase 11 (HSD17B11) LDTP09063 4.60  LDD0143 
Fatty acid 2-hydroxylase (FA2H) LDTP07963 2.22  LDD0142 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 2.09  LDD0143 
Ferrochelatase, mitochondrial (FECH) LDTP03198 4.83  LDD0142 
Ferroptosis suppressor protein 1 (AIFM2) LDTP11124 16.14  LDD0143 
Glycerol-3-phosphate acyltransferase 3 (GPAT3) LDTP06885 2.70  LDD0143 
Glycerol-3-phosphate acyltransferase 4 (GPAT4) LDTP08232 2.35  LDD0145 
GPI ethanolamine phosphate transferase 3 (PIGO) LDTP09505 2.28  LDD0145 
GTP-binding protein SAR1a (SAR1A) LDTP12470 2.27  LDD0143 
GTP-binding protein SAR1b (SAR1B) LDTP14231 2.07  LDD0143 
Heme oxygenase 1 (HMOX1) LDTP02359 2.51  LDD0141 
Heme oxygenase 2 (HMOX2) LDTP03540 3.42  LDD0145 
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) LDTP05301 3.78  LDD0335 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 2.01  LDD0145 
Lanosterol synthase (LSS) LDTP04183 2.34  LDD0141 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 4.63  LDD0145 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 3.06  LDD0145 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 2.10  LDD0143 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 3.29  LDD0142 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 2.09  LDD0145 
Mannosyl-oligosaccharide glucosidase (MOGS) LDTP05971 2.52  LDD0145 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 2.42  LDD0142 
NADH-cytochrome b5 reductase 3 (CYB5R3) LDTP01770 2.28  LDD0143 
NADPH--cytochrome P450 reductase (POR) LDTP02848 2.59  LDD0145 
Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 2.78  LDD0145 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 10.58  LDD0142 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 2.06  LDD0144 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 4.98  LDD0330 
Patatin-like phospholipase domain-containing protein 2 (PNPLA2) LDTP10077 2.17  LDD0142 
Patatin-like phospholipase domain-containing protein 6 (PNPLA6) LDTP08617 20.00  LDD0145 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 2.21  LDD0145 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 2.37  LDD0145 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 2.13  LDD0142 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 2.58  LDD0142 
Presequence protease, mitochondrial (PITRM1) LDTP07003 2.06  LDD0141 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 2.74  LDD0145 
Prostaglandin G/H synthase 2 (PTGS2) LDTP03736 3.73  LDD0140 
Prostaglandin reductase 1 (PTGR1) LDTP06227 2.74  LDD0142 
Prostaglandin reductase 2 (PTGR2) LDTP08979 12.00  LDD0141 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 2.14  LDD0142 
Retinol dehydrogenase 10 (RDH10) LDTP08722 3.13  LDD0142 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 3.21  LDD0331 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 3.85  LDD0330 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 2.20  LDD0142 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 2.26  LDD0145 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 2.12  LDD0145 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 4.27  LDD0142 
Serum paraoxonase/lactonase 3 (PON3) LDTP06334 2.93  LDD0145 
Short-chain dehydrogenase/reductase 3 (DHRS3) LDTP01349 2.04  LDD0142 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 3.27  LDD0145 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 2.99  LDD0145 
Squalene monooxygenase (SQLE) LDTP06142 2.29  LDD0143 
Squalene synthase (FDFT1) LDTP03842 2.46  LDD0145 
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) LDTP06455 3.22  LDD0143 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 4.00  LDD0142 
TLC domain-containing protein 1 (TLCD1) LDTP10182 11.70  LDD0145 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 2.44  LDD0142 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 2.53  LDD0143 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 2.55  LDD0143 
Tubulin alpha-8 chain (TUBA8) LDTP12810 2.73  LDD0143 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 2.12  LDD0143 
UDP-glucuronosyltransferase 1A7 (UGT1A7) LDTP12147 2.11  LDD0142 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 2.97  LDD0145 
------------------------------------------------------------------------------------
⏷ Show the Full List of 95 Enzyme
34 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Calcium load-activated calcium channel (TMCO1) LDTP13599 2.38  LDD0145 
Calnexin (CANX) LDTP03405 2.13  LDD0145 
Caveolin-1 (CAV1) LDTP05394 2.19  LDD0144 
Derlin-1 (DERL1) LDTP11245 2.43  LDD0145 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) LDTP03870 2.03  LDD0145 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 2.24  LDD0145 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 3.41  LDD0332 
Lysosome membrane protein 2 (SCARB2) LDTP06034 2.72  LDD0145 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 2.09  LDD0145 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 3.09  LDD0142 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 6.69  LDD0145 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.00  LDD0145 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 2.76  LDD0144 
Nucleoporin NDC1 (NDC1) LDTP11213 2.78  LDD0145 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 2.38  LDD0145 
Prosaposin (PSAP) LDTP02215 2.34  LDD0144 
Protein GPR107 (GPR107) LDTP07236 2.62  LDD0143 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 2.02  LDD0145 
Protein unc-93 homolog B1 (UNC93B1) LDTP11760 2.06  LDD0142 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 2.06  LDD0145 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 4.77  LDD0145 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 20.00  LDD0144 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 2.08  LDD0145 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 5.25  LDD0145 
Translocation protein SEC63 homolog (SEC63) LDTP13243 2.02  LDD0145 
Transmembrane emp24 domain-containing protein 3 (TMED3) LDTP14002 2.07  LDD0144 
Transmembrane protein 199 (TMEM199) LDTP08881 2.48  LDD0145 
Transmembrane protein 208 (TMEM208) LDTP11214 2.14  LDD0144 
Vacuole membrane protein 1 (VMP1) LDTP10343 2.10  LDD0145 
Vesicular integral-membrane protein VIP36 (LMAN2) LDTP05690 2.04  LDD0143 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 3.34  LDD0145 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 3.35  LDD0145 
Zinc transporter 7 (SLC30A7) LDTP09180 2.14  LDD0145 
Zinc transporter SLC39A7 (SLC39A7) LDTP09769 2.32  LDD0142 
------------------------------------------------------------------------------------
⏷ Show the Full List of 34 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 3.86  LDD0145 
Glucocorticoid receptor (NR3C1) LDTP02016 2.64  LDD0141 
------------------------------------------------------------------------------------
2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 2.40  LDD0144 
Neuroplastin (NPTN) LDTP14205 2.98  LDD0145 
------------------------------------------------------------------------------------
30 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) LDTP08950 14.31  LDD0143 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 3.05  LDD0145 
Annexin A4 (ANXA4) LDTP02354 2.07  LDD0141 
Apolipoprotein L2 (APOL2) LDTP11076 2.16  LDD0143 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 20.00  LDD0336 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 2.10  LDD0143 
FAS-associated factor 2 (FAF2) LDTP10185 4.95  LDD0143 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 2.36  LDD0145 
Integrin alpha-3 (ITGA3) LDTP03342 2.37  LDD0145 
Lipase maturation factor 2 (LMF2) LDTP15887 2.41  LDD0145 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 2.76  LDD0143 
Perilipin-2 (PLIN2) LDTP10889 9.04  LDD0143 
Perilipin-3 (PLIN3) LDTP01021 2.76  LDD0143 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 2.26  LDD0145 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 2.19  LDD0145 
Protein FAM114A2 (FAM114A2) LDTP16080 2.77  LDD0143 
Protein LYRIC (MTDH) LDTP08224 2.06  LDD0145 
Protein YIF1B (YIF1B) LDTP06948 2.09  LDD0145 
Regulator of microtubule dynamics protein 2 (RMDN2) LDTP10567 2.06  LDD0142 
Reticulon-3 (RTN3) LDTP01522 4.54  LDD0145 
Reticulon-4 (RTN4) LDTP12412 2.59  LDD0143 
RUS family member 1 (RUSF1) LDTP10357 2.93  LDD0145 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 2.63  LDD0145 
Torsin-1A-interacting protein 1 (TOR1AIP1) LDTP07012 2.29  LDD0145 
Tubulin beta chain (TUBB) LDTP02205 2.39  LDD0143 
Tubulin beta-2B chain (TUBB2B) LDTP11277 2.31  LDD0143 
Tubulin beta-3 chain (TUBB3) LDTP05904 2.30  LDD0143 
Tubulin beta-4B chain (TUBB4B) LDTP05076 2.35  LDD0143 
Tubulin beta-6 chain (TUBB6) LDTP11233 2.24  LDD0143 
Tumor protein D54 (TPD52L2) LDTP00759 2.79  LDD0143 
------------------------------------------------------------------------------------
⏷ Show the Full List of 30 Other

Competitor(s) Related To This Probe

Competitor ID Name Concentration Cell-system Ref
 LDCM0080  Flurbiprofen 25 uM Human lung adenocarcinoma cells (A-549) [1]
 LDCM0081  Rofecoxib 25 uM Human lung adenocarcinoma cells (A-549) [1]
 LDCM0082  FK866 25 uM Human lung adenocarcinoma cells (A-549) [1]
 LDCM0083  Avasimibe 25 uM Human lung adenocarcinoma cells (A-549) [1]
 LDCM0084  Ro 48-8071 50 uM Human lung adenocarcinoma cells (A-549) [1]
 LDCM0136  SR-4559 5 uM Human normal cells (HEK-293T) [2]
 LDCM0137  SR-4995 5 uM Human normal cells (HEK-293T) [2]
 LDCM0138  KDT501 50 uM Human normal cells (HEK-293T) [2]

Full Information of The Labelling Profiles of This Probe

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
5 uM
Quantitative Method
SILAC
Competitor Name
Flurbiprofen
 Competitor Info 
Competitor Concentration
25 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Lung
Disease Model
Lung adenocarcinoma [ICD-11:2C25]
Model Name
Human lung adenocarcinoma cells (A-549)
Interaction Atlas ID
 LDD0140 
Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
5 uM
Quantitative Method
SILAC
Competitor Name
Rofecoxib
 Competitor Info 
Competitor Concentration
25 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Lung
Disease Model
Lung adenocarcinoma [ICD-11:2C25]
Model Name
Human lung adenocarcinoma cells (A-549)
Interaction Atlas ID
 LDD0141 
Download The Altas
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
5 uM
Quantitative Method
SILAC
Competitor Name
FK866
 Competitor Info 
Competitor Concentration
25 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Lung
Disease Model
Lung adenocarcinoma [ICD-11:2C25]
Model Name
Human lung adenocarcinoma cells (A-549)
Interaction Atlas ID
 LDD0142 
Download The Altas
  
Experiment 4 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
5 uM
Quantitative Method
SILAC
Competitor Name
Avasimibe
 Competitor Info 
Competitor Concentration
25 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Lung
Disease Model
Lung adenocarcinoma [ICD-11:2C25]
Model Name
Human lung adenocarcinoma cells (A-549)
Interaction Atlas ID
 LDD0143 
Download The Altas
  
Experiment 5 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
5 uM
Quantitative Method
SILAC
Competitor Name
Ro 48-8071
 Competitor Info 
Competitor Concentration
5 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Lung
Disease Model
Lung adenocarcinoma [ICD-11:2C25]
Model Name
Human lung adenocarcinoma cells (A-549)
Interaction Atlas ID
 LDD0144 
Download The Altas
  
Experiment 6 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
5 uM
Quantitative Method
SILAC
Competitor Name
Ro 48-8071
 Competitor Info 
Competitor Concentration
50 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Lung
Disease Model
Lung adenocarcinoma [ICD-11:2C25]
Model Name
Human lung adenocarcinoma cells (A-549)
Interaction Atlas ID
 LDD0145 
Download The Altas
  
Experiment 7 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
SR-4559
 Competitor Info 
Competitor Concentration
5 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
 LDD0329 
Download The Altas
  
Experiment 8 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
SR-4559
 Competitor Info 
Competitor Concentration
25 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
 LDD0330 
Download The Altas
  
Experiment 9 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
SR-4995
 Competitor Info 
Competitor Concentration
5 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
 LDD0331 
Download The Altas
  
Experiment 10 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
SR-4995
 Competitor Info 
Competitor Concentration
25 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
 LDD0332 
Download The Altas
  
Experiment 11 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
KDT501
 Competitor Info 
Competitor Concentration
25 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
 LDD0335 
Download The Altas
  
Experiment 12 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
KDT501
 Competitor Info 
Competitor Concentration
50 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
 LDD0336 
Download The Altas

References

1 A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045.
2 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570