General Information of Experiment

Probe Name A-DA  Probe Info 
Probe concentration 5 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Ro 48-8071  Competitor Info 
Competitor Concentration 5 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Lung
Disease Model Lung adenocarcinoma [ICD-11:2C25]
Model Name Human lung adenocarcinoma cells (A-549)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04183  Lanosterol synthase (LSS) 20.0
 LDTP06325  3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) 16.0
 LDTP07766  Ceramide synthase 6 (CERS6) 2.7
 LDTP03736  Prostaglandin G/H synthase 2 (PTGS2) 2.5
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 2.5
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 2.3
 LDTP11124  Ferroptosis suppressor protein 1 (AIFM2) 2.2
 LDTP08979  Prostaglandin reductase 2 (PTGR2) 2.1
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 2.1
 LDTP10077  Patatin-like phospholipase domain-containing protein 2 (PNPLA2) 2.0
Transporter and channel
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 20.0
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 2.8
 LDTP02215  Prosaposin (PSAP) 2.3
 LDTP05394  Caveolin-1 (CAV1) 2.2
 LDTP11214  Transmembrane protein 208 (TMEM208) 2.1
 LDTP14002  Transmembrane emp24 domain-containing protein 3 (TMED3) 2.1
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03772  Basigin (BSG) 2.4

References

1 A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045.