Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | A-DA | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 5 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
SILAC
|
|||||
| Competitor Name | Ro 48-8071 | Competitor Info | ||||
| Competitor Concentration | 5 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Lung | ||||
| Disease Model | Lung adenocarcinoma [ICD-11:2C25] | |||||
| Model Name | Human lung adenocarcinoma cells (A-549) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP04183 | Lanosterol synthase (LSS) | 20.0 | ||||
| LDTP06325 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) | 16.0 | ||||
| LDTP07766 | Ceramide synthase 6 (CERS6) | 2.7 | ||||
| LDTP03736 | Prostaglandin G/H synthase 2 (PTGS2) | 2.5 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 2.5 | ||||
| LDTP06200 | Delta(14)-sterol reductase LBR (LBR) | 2.3 | ||||
| LDTP11124 | Ferroptosis suppressor protein 1 (AIFM2) | 2.2 | ||||
| LDTP08979 | Prostaglandin reductase 2 (PTGR2) | 2.1 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 2.1 | ||||
| LDTP10077 | Patatin-like phospholipase domain-containing protein 2 (PNPLA2) | 2.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 20.0 | ||||
| LDTP00541 | NPC intracellular cholesterol transporter 1 (NPC1) | 2.8 | ||||
| LDTP02215 | Prosaposin (PSAP) | 2.3 | ||||
| LDTP05394 | Caveolin-1 (CAV1) | 2.2 | ||||
| LDTP11214 | Transmembrane protein 208 (TMEM208) | 2.1 | ||||
| LDTP14002 | Transmembrane emp24 domain-containing protein 3 (TMED3) | 2.1 | ||||
Immunoglobulin
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03772 | Basigin (BSG) | 2.4 | ||||
