Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | A-DA | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 5 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
SILAC
|
|||||
| Competitor Name | FK866 | Competitor Info | ||||
| Competitor Concentration | 25 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Lung | ||||
| Disease Model | Lung adenocarcinoma [ICD-11:2C25] | |||||
| Model Name | Human lung adenocarcinoma cells (A-549) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP04051 | Nicotinamide phosphoribosyltransferase (NAMPT) | 10.6 | ||||
| LDTP03198 | Ferrochelatase, mitochondrial (FECH) | 4.8 | ||||
| LDTP03257 | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) | 4.4 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 4.3 | ||||
| LDTP10887 | Synaptic vesicle membrane protein VAT-1 homolog (VAT1) | 4.0 | ||||
| LDTP07504 | Lysophospholipid acyltransferase 5 (LPCAT3) | 3.3 | ||||
| LDTP03976 | Aldo-keto reductase family 1 member C3 (AKR1C3) | 3.3 | ||||
| LDTP08722 | Retinol dehydrogenase 10 (RDH10) | 3.1 | ||||
| LDTP06227 | Prostaglandin reductase 1 (PTGR1) | 2.7 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 2.6 | ||||
| LDTP03912 | Trifunctional enzyme subunit alpha, mitochondrial (HADHA) | 2.4 | ||||
| LDTP01168 | NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) | 2.4 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 2.3 | ||||
| LDTP04453 | Arylsulfatase L (ARSL) | 2.3 | ||||
| LDTP07963 | Fatty acid 2-hydroxylase (FA2H) | 2.2 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 2.2 | ||||
| LDTP10077 | Patatin-like phospholipase domain-containing protein 2 (PNPLA2) | 2.2 | ||||
| LDTP09666 | Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) | 2.1 | ||||
| LDTP08859 | Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) | 2.1 | ||||
| LDTP12147 | UDP-glucuronosyltransferase 1A7 (UGT1A7) | 2.1 | ||||
| LDTP01349 | Short-chain dehydrogenase/reductase 3 (DHRS3) | 2.0 | ||||
| LDTP04437 | Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) | 2.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 3.1 | ||||
| LDTP09769 | Zinc transporter SLC39A7 (SLC39A7) | 2.3 | ||||
| LDTP11760 | Protein unc-93 homolog B1 (UNC93B1) | 2.1 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10567 | Regulator of microtubule dynamics protein 2 (RMDN2) | 2.1 | ||||
| LDTP02354 | Annexin A4 (ANXA4) | 2.0 | ||||
