General Information of Experiment

Probe Name A-DA  Probe Info 
Probe concentration 5 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name FK866  Competitor Info 
Competitor Concentration 25 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Lung
Disease Model Lung adenocarcinoma [ICD-11:2C25]
Model Name Human lung adenocarcinoma cells (A-549)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 22 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 10.6
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 4.8
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 4.4
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 4.3
 LDTP10887  Synaptic vesicle membrane protein VAT-1 homolog (VAT1) 4.0
 LDTP07504  Lysophospholipid acyltransferase 5 (LPCAT3) 3.3
 LDTP03976  Aldo-keto reductase family 1 member C3 (AKR1C3) 3.3
 LDTP08722  Retinol dehydrogenase 10 (RDH10) 3.1
 LDTP06227  Prostaglandin reductase 1 (PTGR1) 2.7
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 2.6
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 2.4
 LDTP01168  NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) 2.4
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 2.3
 LDTP04453  Arylsulfatase L (ARSL) 2.3
 LDTP07963  Fatty acid 2-hydroxylase (FA2H) 2.2
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 2.2
 LDTP10077  Patatin-like phospholipase domain-containing protein 2 (PNPLA2) 2.2
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 2.1
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 2.1
 LDTP12147  UDP-glucuronosyltransferase 1A7 (UGT1A7) 2.1
 LDTP01349  Short-chain dehydrogenase/reductase 3 (DHRS3) 2.0
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 2.0
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 3.1
 LDTP09769  Zinc transporter SLC39A7 (SLC39A7) 2.3
 LDTP11760  Protein unc-93 homolog B1 (UNC93B1) 2.1
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10567  Regulator of microtubule dynamics protein 2 (RMDN2) 2.1
 LDTP02354  Annexin A4 (ANXA4) 2.0

References

1 A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045.