Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | Johansson_61 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 10 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
SILAC
|
|||||
| Competitor Name | Fragment61 | Competitor Info | ||||
| Competitor Concentration | 30 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Cell lysate | |||
| Derived Tissue |
|
Bone marrow | ||||
| Disease Model | T acute lymphoblastic leukemia [ICD-11:2A90] | |||||
| Model Name | Human T acute lymphoblastic leukemia cell lysate (Jurkat) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03458 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) | 20.0 | ||||
| LDTP06699 | AP2-associated protein kinase 1 (AAK1) | 20.0 | ||||
| LDTP04358 | Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) | 20.0 | ||||
| LDTP19892 | DGAT1/2-independent enzyme synthesizing storage lipids (TMEM68) | 20.0 | ||||
| LDTP05128 | Glutathione S-transferase omega-1 (GSTO1) | 20.0 | ||||
| LDTP13219 | GTPase IMAP family member 2 (GIMAP2) | 20.0 | ||||
| LDTP02852 | Methylated-DNA--protein-cysteine methyltransferase (MGMT) | 20.0 | ||||
| LDTP07591 | Neutral cholesterol ester hydrolase 1 (NCEH1) | 20.0 | ||||
| LDTP01649 | Phosphatidate cytidylyltransferase 2 (CDS2) | 20.0 | ||||
| LDTP03831 | Phospholipid hydroperoxide glutathione peroxidase GPX4 (GPX4) | 20.0 | ||||
| LDTP13904 | Probable ATP-dependent RNA helicase DDX52 (DDX52) | 20.0 | ||||
| LDTP09023 | Probable E3 ubiquitin-protein ligase MARCHF10 (MARCHF10) | 20.0 | ||||
| LDTP05850 | Probable methyltransferase TARBP1 (TARBP1) | 20.0 | ||||
| LDTP12040 | Prostaglandin E synthase 2 (PTGES2) | 20.0 | ||||
| LDTP11294 | Protein adenylyltransferase SelO, mitochondrial (SELENOO) | 20.0 | ||||
| LDTP17022 | Secernin-3 (SCRN3) | 20.0 | ||||
| LDTP03163 | Sterol carrier protein 2 (SCP2) | 20.0 | ||||
| LDTP04988 | Thioredoxin reductase-like selenoprotein T (SELENOT) | 20.0 | ||||
| LDTP09749 | Titin (TTN) | 20.0 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 17.9 | ||||
| LDTP08232 | Glycerol-3-phosphate acyltransferase 4 (GPAT4) | 17.3 | ||||
| LDTP09344 | Prostamide/prostaglandin F synthase (PRXL2B) | 17.0 | ||||
| LDTP06721 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) | 15.4 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 15.1 | ||||
| LDTP11178 | Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) | 14.8 | ||||
| LDTP11107 | Serine/threonine-protein phosphatase CPPED1 (CPPED1) | 14.7 | ||||
| LDTP14264 | Choline/ethanolaminephosphotransferase 1 (CEPT1) | 14.4 | ||||
| LDTP15370 | Pseudouridylate synthase RPUSD2 (RPUSD2) | 12.4 | ||||
| LDTP01704 | Phosphatidylserine lipase ABHD16A (ABHD16A) | 12.1 | ||||
| LDTP01039 | Protein-S-isoprenylcysteine O-methyltransferase (ICMT) | 11.5 | ||||
| LDTP04471 | Ribosomal protein S6 kinase alpha-3 (RPS6KA3) | 11.5 | ||||
| LDTP12444 | Xaa-Pro aminopeptidase 1 (XPNPEP1) | 10.3 | ||||
| LDTP01394 | DNA fragmentation factor subunit beta (DFFB) | 8.5 | ||||
| LDTP03230 | Tyrosine-protein kinase JAK1 (JAK1) | 7.9 | ||||
| LDTP06363 | Ribosomal protein S6 kinase alpha-2 (RPS6KA2) | 6.1 | ||||
| LDTP12297 | Thioredoxin reductase 2, mitochondrial (TXNRD2) | 5.3 | ||||
| LDTP02860 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) | 5.2 | ||||
| LDTP04333 | GMP synthase [glutamine-hydrolyzing] (GMPS) | 4.9 | ||||
| LDTP02622 | Creatine kinase U-type, mitochondrial (CKMT1A; CKMT1B) | 4.6 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP11987 | Reticulophagy regulator 1 (RETREG1) | 20.0 | ||||
| LDTP00970 | Gasdermin-E (GSDME) | 13.0 | ||||
| LDTP03559 | High affinity cationic amino acid transporter 1 (SLC7A1) | 10.5 | ||||
| LDTP09038 | Mixed lineage kinase domain-like protein (MLKL) | 8.7 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 6.8 | ||||
| LDTP01060 | PRA1 family protein 2 (PRAF2) | 4.1 | ||||
Transcription factor
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP06690 | DNA-binding protein RFX7 (RFX7) | 15.3 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP14095 | Ankyrin repeat and SOCS box protein 3 (ASB3) | 20.0 | ||||
| LDTP07419 | Centromere protein P (CENPP) | 20.0 | ||||
| LDTP01002 | Cyclin-T1 (CCNT1) | 20.0 | ||||
| LDTP06804 | Girdin (CCDC88A) | 20.0 | ||||
| LDTP12904 | Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) | 20.0 | ||||
| LDTP09969 | Lipoma-preferred partner (LPP) | 20.0 | ||||
| LDTP11140 | Peroxiredoxin-like 2A (PRXL2A) | 20.0 | ||||
| LDTP01522 | Reticulon-3 (RTN3) | 20.0 | ||||
| LDTP14236 | Selenoprotein K (SELENOK) | 20.0 | ||||
| LDTP15599 | UPF0729 protein C18orf32 (C18orf32) | 20.0 | ||||
| LDTP12412 | Reticulon-4 (RTN4) | 16.0 | ||||
| LDTP10357 | RUS family member 1 (RUSF1) | 12.7 | ||||
| LDTP18400 | DENN domain-containing protein 2D (DENND2D) | 10.8 | ||||
| LDTP05648 | General transcription factor 3C polypeptide 1 (GTF3C1) | 10.6 | ||||
| LDTP13786 | TRAF3-interacting JNK-activating modulator (TRAF3IP3) | 10.5 | ||||
| LDTP01195 | Core histone macro-H2A.1 (MACROH2A1) | 10.3 | ||||
| LDTP05257 | Receptor expression-enhancing protein 5 (REEP5) | 9.9 | ||||