Details of the Target

General Information of Target

Target ID LDTP04358
Target Name Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)
Gene Name CPT1A
Gene ID 1374
Synonyms
CPT1; Carnitine O-palmitoyltransferase 1, liver isoform; CPT1-L; EC 2.3.1.21; Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPS
SWLIVVVGVMTTMYAKIDPSLGIIAKINRTLETANCMSSQTKNVVSGVLFGTGLWVALIV
TMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPAVK
DTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYI
YLRGRGPLMVNSNYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGST
IPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREME
QQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTL
DETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPI
VAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLL
ANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREG
RTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCL
YVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGY
GVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSNSKK
Target Bioclass
Enzyme
Family
Carnitine/choline acetyltransferase family
Subcellular location
Mitochondrion outer membrane
Function
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in hepatic triglyceride metabolism.
Uniprot ID
P50416
Ensemble ID
ENST00000265641.10
HGNC ID
HGNC:2328
ChEMBL ID
CHEMBL1293194

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CASKI SNV: p.V663L DBIA    Probe Info 
CHL1 SNV: p.R601M .
HCT15 SNV: p.Q495Ter; p.Y514C DBIA    Probe Info 
JURKAT SNV: p.R645H Compound 10    Probe Info 
KYM1 Substitution: p.R29I DBIA    Probe Info 
MCC13 Substitution: p.H277Y DBIA    Probe Info 
MFE319 Deletion: p.E525NfsTer6 .
SUPT1 SNV: p.R123H DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 36 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		9.37  LDD0402  [1]
HDSF-alk
 Probe Info  		2.38  LDD0197  [2]
CY-1
 Probe Info  		100.00  LDD0243  [3]
CY4
 Probe Info  		100.00  LDD0244  [3]
N1
 Probe Info  		100.00  LDD0242  [3]
TH211
 Probe Info  		Y666(7.54)  LDD0260  [4]
YN-1
 Probe Info  		100.00  LDD0444  [5]
YN-4
 Probe Info  		100.00  LDD0445  [5]
STPyne
 Probe Info  		K180(7.64); K285(10.00); K634(8.89); K639(4.91)  LDD0277  [6]
BTD
 Probe Info  		C742(5.62)  LDD1699  [7]
ONAyne
 Probe Info  		K292(10.00)  LDD0275  [6]
JZ128-DTB
 Probe Info  		C96(0.00); C304(0.00)  LDD0462  [8]
Sulforaphane-probe2
 Probe Info  		1.30  LDD0160  [9]
Johansson_61
 Probe Info  		_(11.43)  LDD1485  [10]
Alkyne-RA190
 Probe Info  		5.31  LDD0299  [11]
EA-probe
 Probe Info  		C304(2.54)  LDD2210  [12]
DBIA
 Probe Info  		C96(1.14); C608(0.98); C613(0.98)  LDD0078  [13]
4-Iodoacetamidophenylacetylene
 Probe Info  		C742(0.00); C96(0.00)  LDD0038  [14]
IA-alkyne
 Probe Info  		C742(0.00); C304(0.00); C526(0.00); C96(0.00)  LDD0036  [14]
Lodoacetamide azide
 Probe Info  		C742(0.00); C526(0.00); C96(0.00); C586(0.00)  LDD0037  [14]
JW-RF-010
 Probe Info  		C96(0.00); C742(0.00)  LDD0026  [15]
TFBX
 Probe Info  		N.A.  LDD0027  [15]
WYneN
 Probe Info  		C742(0.00); C96(0.00); C304(0.00)  LDD0021  [16]
WYneO
 Probe Info  		C96(0.00); C742(0.00)  LDD0022  [16]
Compound 10
 Probe Info  		N.A.  LDD2216  [17]
Compound 11
 Probe Info  		N.A.  LDD2213  [17]
ENE
 Probe Info  		N.A.  LDD0006  [16]
IPM
 Probe Info  		C586(0.00); C96(0.00)  LDD0005  [16]
VSF
 Probe Info  		N.A.  LDD0007  [16]
Acrolein
 Probe Info  		C304(0.00); C742(0.00); C608(0.00); C96(0.00)  LDD0217  [18]
Cinnamaldehyde
 Probe Info  		C96(0.00); C613(0.00); C742(0.00)  LDD0220  [18]
Crotonaldehyde
 Probe Info  		C608(0.00); C742(0.00); C96(0.00); C304(0.00)  LDD0219  [18]
Methacrolein
 Probe Info  		C96(0.00); C742(0.00); C608(0.00); C304(0.00)  LDD0218  [18]
W1
 Probe Info  		C304(0.00); C96(0.00)  LDD0236  [19]
AOyne
 Probe Info  		9.70  LDD0443  [20]
NAIA_5
 Probe Info  		C394(0.00); C448(0.00); C586(0.00); C742(0.00)  LDD2223  [21]
PAL-AfBPP Probe
Click To Hide/Show 34 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C027
 Probe Info  		7.57  LDD1733  [22]
C040
 Probe Info  		8.00  LDD1740  [22]
C056
 Probe Info  		22.47  LDD1753  [22]
C143
 Probe Info  		13.74  LDD1825  [22]
C153
 Probe Info  		16.22  LDD1834  [22]
C159
 Probe Info  		7.21  LDD1839  [22]
C169
 Probe Info  		22.32  LDD1849  [22]
C228
 Probe Info  		25.28  LDD1901  [22]
C238
 Probe Info  		12.91  LDD1911  [22]
C243
 Probe Info  		11.63  LDD1916  [22]
C246
 Probe Info  		15.45  LDD1919  [22]
C251
 Probe Info  		35.02  LDD1924  [22]
C252
 Probe Info  		12.64  LDD1925  [22]
C285
 Probe Info  		21.56  LDD1955  [22]
C289
 Probe Info  		39.12  LDD1959  [22]
C299
 Probe Info  		5.74  LDD1968  [22]
C343
 Probe Info  		12.47  LDD2005  [22]
C348
 Probe Info  		10.85  LDD2009  [22]
C349
 Probe Info  		22.94  LDD2010  [22]
C350
 Probe Info  		56.49  LDD2011  [22]
C376
 Probe Info  		6.92  LDD2036  [22]
C382
 Probe Info  		10.85  LDD2041  [22]
C388
 Probe Info  		48.84  LDD2047  [22]
C390
 Probe Info  		39.40  LDD2049  [22]
C403
 Probe Info  		14.93  LDD2061  [22]
C407
 Probe Info  		15.03  LDD2064  [22]
FFF probe11
 Probe Info  		20.00  LDD0471  [23]
FFF probe13
 Probe Info  		20.00  LDD0475  [23]
FFF probe14
 Probe Info  		20.00  LDD0477  [23]
JN0003
 Probe Info  		20.00  LDD0469  [23]
STS-1
 Probe Info  		N.A.  LDD0136  [24]
STS-2
 Probe Info  		N.A.  LDD0138  [24]
VE-P
 Probe Info  		N.A.  LDD0396  [25]
OEA-DA
 Probe Info  		17.27  LDD0046  [26]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C742(1.17)  LDD2142  [7]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C742(1.01)  LDD2112  [7]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C742(0.95)  LDD2095  [7]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C742(0.87)  LDD2130  [7]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C742(1.30); C96(0.98)  LDD2117  [7]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C742(1.51)  LDD2152  [7]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C742(0.65)  LDD2132  [7]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C742(0.75); C96(0.55)  LDD2131  [7]
 LDCM0214  AC1 HCT 116 C96(0.85); C304(1.06); C586(1.17); C608(0.84)  LDD0531  [13]
 LDCM0215  AC10 HCT 116 C96(1.12); C304(0.86); C608(0.93); C613(1.05)  LDD0532  [13]
 LDCM0216  AC100 HCT 116 C96(0.95); C304(0.65); C608(0.66); C613(0.66)  LDD0533  [13]
 LDCM0217  AC101 HCT 116 C96(1.04); C304(0.64); C608(0.72); C613(0.72)  LDD0534  [13]
 LDCM0218  AC102 HCT 116 C96(1.09); C304(0.65); C608(0.95); C613(0.95)  LDD0535  [13]
 LDCM0219  AC103 HCT 116 C96(1.05); C304(0.62); C608(0.59); C613(0.59)  LDD0536  [13]
 LDCM0220  AC104 HCT 116 C96(0.94); C304(0.60); C608(1.07); C613(1.07)  LDD0537  [13]
 LDCM0221  AC105 HCT 116 C96(0.95); C304(0.61); C608(0.77); C613(0.77)  LDD0538  [13]
 LDCM0222  AC106 HCT 116 C96(0.96); C304(0.63); C608(0.84); C613(0.84)  LDD0539  [13]
 LDCM0223  AC107 HCT 116 C96(0.92); C304(0.59); C608(0.94); C613(0.94)  LDD0540  [13]
 LDCM0224  AC108 HCT 116 C96(1.06); C304(0.77); C608(0.70); C613(0.70)  LDD0541  [13]
 LDCM0225  AC109 HCT 116 C96(1.07); C304(0.85); C608(1.06); C613(1.06)  LDD0542  [13]
 LDCM0226  AC11 HCT 116 C96(1.40); C304(0.86); C608(0.95); C613(1.16)  LDD0543  [13]
 LDCM0227  AC110 HCT 116 C96(1.13); C304(0.75); C608(0.67); C613(0.67)  LDD0544  [13]
 LDCM0228  AC111 HCT 116 C96(1.09); C304(0.74); C608(0.80); C613(0.80)  LDD0545  [13]
 LDCM0229  AC112 HCT 116 C96(1.03); C304(0.61); C608(0.65); C613(0.65)  LDD0546  [13]
 LDCM0230  AC113 HCT 116 C96(0.97); C304(1.10); C608(1.10); C613(1.17)  LDD0547  [13]
 LDCM0231  AC114 HCT 116 C96(0.99); C304(1.01); C608(0.89); C613(0.95)  LDD0548  [13]
 LDCM0232  AC115 HCT 116 C96(1.12); C304(0.81); C608(1.06); C613(0.88)  LDD0549  [13]
 LDCM0233  AC116 HCT 116 C96(1.13); C304(0.86); C608(1.06); C613(0.89)  LDD0550  [13]
 LDCM0234  AC117 HCT 116 C96(1.13); C304(0.91); C608(0.98); C613(1.19)  LDD0551  [13]
 LDCM0235  AC118 HCT 116 C96(1.19); C304(1.01); C608(0.98); C613(1.16)  LDD0552  [13]
 LDCM0236  AC119 HCT 116 C96(1.13); C304(0.89); C608(0.94); C613(1.07)  LDD0553  [13]
 LDCM0237  AC12 HCT 116 C96(1.16); C304(1.08); C608(1.03); C613(1.41)  LDD0554  [13]
 LDCM0238  AC120 HCT 116 C96(1.09); C304(0.97); C608(0.81); C613(0.81)  LDD0555  [13]
 LDCM0239  AC121 HCT 116 C96(1.13); C304(1.11); C608(1.08); C613(1.28)  LDD0556  [13]
 LDCM0240  AC122 HCT 116 C96(0.97); C304(0.92); C608(1.07); C613(1.11)  LDD0557  [13]
 LDCM0241  AC123 HCT 116 C96(1.33); C304(1.16); C608(0.80); C613(0.89)  LDD0558  [13]
 LDCM0242  AC124 HCT 116 C96(1.07); C304(1.09); C608(1.02); C613(1.19)  LDD0559  [13]
 LDCM0243  AC125 HCT 116 C96(1.02); C304(0.92); C608(1.04); C613(1.07)  LDD0560  [13]
 LDCM0244  AC126 HCT 116 C96(1.10); C304(0.94); C608(0.97); C613(0.96)  LDD0561  [13]
 LDCM0245  AC127 HCT 116 C96(1.13); C304(0.87); C608(1.04); C613(1.32)  LDD0562  [13]
 LDCM0246  AC128 HCT 116 C96(1.02); C304(1.24); C586(1.34); C608(1.03)  LDD0563  [13]
 LDCM0247  AC129 HCT 116 C96(0.89); C304(1.29); C586(1.16); C608(0.90)  LDD0564  [13]
 LDCM0249  AC130 HCT 116 C96(1.06); C304(1.06); C586(1.19); C608(0.99)  LDD0566  [13]
 LDCM0250  AC131 HCT 116 C96(0.97); C304(1.19); C586(1.12); C608(0.98)  LDD0567  [13]
 LDCM0251  AC132 HCT 116 C96(1.17); C304(1.29); C586(2.04); C608(0.93)  LDD0568  [13]
 LDCM0252  AC133 HCT 116 C96(1.07); C304(1.18); C586(1.58); C608(1.10)  LDD0569  [13]
 LDCM0253  AC134 HCT 116 C96(1.09); C304(1.21); C586(1.17); C608(0.76)  LDD0570  [13]
 LDCM0254  AC135 HCT 116 C96(1.08); C304(1.17); C586(1.39); C608(1.07)  LDD0571  [13]
 LDCM0255  AC136 HCT 116 C96(1.10); C304(1.31); C586(1.34); C608(1.26)  LDD0572  [13]
 LDCM0256  AC137 HCT 116 C96(1.05); C304(1.21); C586(1.88); C608(1.16)  LDD0573  [13]
 LDCM0257  AC138 HCT 116 C96(1.11); C304(1.28); C586(1.30); C608(0.72)  LDD0574  [13]
 LDCM0258  AC139 HCT 116 C96(1.12); C304(1.25); C586(1.62); C608(0.88)  LDD0575  [13]
 LDCM0259  AC14 HCT 116 C96(0.86); C304(0.85); C608(0.93); C613(1.21)  LDD0576  [13]
 LDCM0260  AC140 HCT 116 C96(1.23); C304(1.21); C586(1.78); C608(0.71)  LDD0577  [13]
 LDCM0261  AC141 HCT 116 C96(1.20); C304(1.08); C586(1.77); C608(0.68)  LDD0578  [13]
 LDCM0262  AC142 HCT 116 C96(1.06); C304(1.17); C586(1.89); C608(0.97)  LDD0579  [13]
 LDCM0263  AC143 HCT 116 C96(1.26); C304(0.94); C608(0.96); C613(0.95)  LDD0580  [13]
 LDCM0264  AC144 HCT 116 C742(0.30); C304(0.87); C608(0.97); C613(1.01)  LDD0581  [13]
 LDCM0265  AC145 HCT 116 C742(0.66); C304(1.02); C608(1.09); C613(1.37)  LDD0582  [13]
 LDCM0266  AC146 HCT 116 C742(0.48); C613(0.88); C608(0.91); C304(1.15)  LDD0583  [13]
 LDCM0267  AC147 HCT 116 C742(0.29); C304(0.86); C613(0.91); C608(1.04)  LDD0584  [13]
 LDCM0268  AC148 HCT 116 C742(0.26); C608(0.76); C613(0.97); C304(1.03)  LDD0585  [13]
 LDCM0269  AC149 HCT 116 C742(0.29); C613(0.69); C608(0.84); C304(1.11)  LDD0586  [13]
 LDCM0270  AC15 HCT 116 C742(0.57); C304(0.84); C96(0.86); C608(1.05)  LDD0587  [13]
 LDCM0271  AC150 HCT 116 C742(0.80); C608(0.91); C613(0.92); C304(1.13)  LDD0588  [13]
 LDCM0272  AC151 HCT 116 C613(0.77); C742(0.95); C304(1.01); C608(1.02)  LDD0589  [13]
 LDCM0273  AC152 HCT 116 C742(0.28); C608(0.71); C613(0.89); C304(1.04)  LDD0590  [13]
 LDCM0274  AC153 HCT 116 C742(0.29); C608(0.67); C613(1.04); C304(1.39)  LDD0591  [13]
 LDCM0621  AC154 HCT 116 C96(1.61); C304(1.02); C608(0.85); C613(0.95)  LDD2158  [13]
 LDCM0622  AC155 HCT 116 C96(1.15); C304(1.06); C608(0.95); C613(1.21)  LDD2159  [13]
 LDCM0623  AC156 HCT 116 C96(1.25); C304(1.32); C608(0.82); C613(0.90)  LDD2160  [13]
 LDCM0624  AC157 HCT 116 C96(1.12); C304(1.12); C608(0.76); C613(0.85)  LDD2161  [13]
 LDCM0276  AC17 HCT 116 C586(0.55); C96(0.73); C742(0.80); C613(1.03)  LDD0593  [13]
 LDCM0277  AC18 HCT 116 C742(0.29); C613(0.77); C608(0.78); C586(0.93)  LDD0594  [13]
 LDCM0278  AC19 HCT 116 C742(0.62); C586(0.80); C613(0.88); C608(0.94)  LDD0595  [13]
 LDCM0279  AC2 HCT 116 C608(0.88); C613(0.88); C304(0.94); C586(0.96)  LDD0596  [13]
 LDCM0280  AC20 HCT 116 C586(0.86); C742(0.91); C613(0.91); C608(0.93)  LDD0597  [13]
 LDCM0281  AC21 HCT 116 C586(0.65); C742(0.68); C613(0.81); C608(0.85)  LDD0598  [13]
 LDCM0282  AC22 HCT 116 C586(0.63); C608(0.93); C613(0.94); C96(1.09)  LDD0599  [13]
 LDCM0283  AC23 HCT 116 C586(0.67); C742(0.77); C613(0.96); C608(0.97)  LDD0600  [13]
 LDCM0284  AC24 HCT 116 C586(0.68); C742(0.84); C613(0.93); C608(0.95)  LDD0601  [13]
 LDCM0285  AC25 HCT 116 C608(0.61); C613(0.71); C304(0.90); C742(0.97)  LDD0602  [13]
 LDCM0286  AC26 HCT 116 C613(0.44); C608(0.55); C742(0.72); C304(0.79)  LDD0603  [13]
 LDCM0287  AC27 HCT 116 C613(0.64); C608(0.70); C304(0.80); C742(0.83)  LDD0604  [13]
 LDCM0288  AC28 HCT 116 C613(0.65); C742(0.69); C304(0.88); C608(1.04)  LDD0605  [13]
 LDCM0289  AC29 HCT 116 C613(0.65); C608(0.66); C742(0.72); C304(0.85)  LDD0606  [13]
 LDCM0290  AC3 HCT 116 C613(0.91); C608(0.92); C96(0.97); C304(1.04)  LDD0607  [13]
 LDCM0291  AC30 HCT 116 C613(0.52); C608(0.62); C742(0.74); C304(0.78)  LDD0608  [13]
 LDCM0292  AC31 HCT 116 C613(0.52); C608(0.64); C742(0.78); C304(0.87)  LDD0609  [13]
 LDCM0293  AC32 HCT 116 C613(0.41); C608(0.59); C742(0.61); C304(0.75)  LDD0610  [13]
 LDCM0294  AC33 HCT 116 C742(0.61); C613(0.61); C304(0.70); C608(0.80)  LDD0611  [13]
 LDCM0295  AC34 HCT 116 C742(0.55); C608(0.64); C613(0.69); C304(0.78)  LDD0612  [13]
 LDCM0296  AC35 HCT 116 C304(0.99); C96(1.06); C586(1.19); C608(1.35)  LDD0613  [13]
 LDCM0297  AC36 HCT 116 C304(0.89); C96(0.94); C608(1.17); C586(1.26)  LDD0614  [13]
 LDCM0298  AC37 HCT 116 C304(0.83); C96(0.98); C586(1.28); C608(1.31)  LDD0615  [13]
 LDCM0299  AC38 HCT 116 C304(0.82); C96(1.00); C613(1.00); C608(1.08)  LDD0616  [13]
 LDCM0300  AC39 HCT 116 C304(0.86); C96(1.06); C608(1.06); C613(1.09)  LDD0617  [13]
 LDCM0301  AC4 HCT 116 C608(0.70); C613(0.72); C742(0.73); C96(1.00)  LDD0618  [13]
 LDCM0302  AC40 HCT 116 C304(0.81); C586(0.87); C742(1.03); C96(1.03)  LDD0619  [13]
 LDCM0303  AC41 HCT 116 C304(0.81); C742(1.21); C96(1.22); C613(1.23)  LDD0620  [13]
 LDCM0304  AC42 HCT 116 C304(0.85); C96(1.08); C742(1.12); C613(1.14)  LDD0621  [13]
 LDCM0305  AC43 HCT 116 C304(0.74); C586(1.06); C742(1.13); C96(1.15)  LDD0622  [13]
 LDCM0306  AC44 HCT 116 C304(0.65); C96(0.99); C586(1.06); C742(1.42)  LDD0623  [13]
 LDCM0307  AC45 HCT 116 C304(0.61); C96(1.08); C586(1.17); C742(1.18)  LDD0624  [13]
 LDCM0308  AC46 HCT 116 C304(0.97); C742(0.99); C96(1.16); C586(1.46)  LDD0625  [13]
 LDCM0309  AC47 HCT 116 C586(0.78); C304(0.96); C742(0.96); C96(1.05)  LDD0626  [13]
 LDCM0310  AC48 HCT 116 C304(0.89); C96(1.16); C742(1.27); C586(1.40)  LDD0627  [13]
 LDCM0311  AC49 HCT 116 C586(0.80); C742(0.89); C304(1.03); C96(1.23)  LDD0628  [13]
 LDCM0312  AC5 HCT 116 C742(0.73); C608(0.82); C613(0.85); C96(0.98)  LDD0629  [13]
 LDCM0313  AC50 HCT 116 C742(0.84); C586(0.95); C304(1.05); C96(1.18)  LDD0630  [13]
 LDCM0314  AC51 HCT 116 C586(0.95); C304(1.08); C96(1.24); C742(1.66)  LDD0631  [13]
 LDCM0315  AC52 HCT 116 C742(0.96); C304(1.09); C586(1.14); C96(1.21)  LDD0632  [13]
 LDCM0316  AC53 HCT 116 C742(0.84); C586(0.95); C304(1.04); C96(1.07)  LDD0633  [13]
 LDCM0317  AC54 HCT 116 C742(1.00); C304(1.06); C96(1.09); C586(1.11)  LDD0634  [13]
 LDCM0318  AC55 HCT 116 C742(0.75); C586(0.92); C96(0.95); C304(1.03)  LDD0635  [13]
 LDCM0319  AC56 HCT 116 C586(0.75); C742(1.08); C96(1.12); C304(1.14)  LDD0636  [13]
 LDCM0320  AC57 HCT 116 C742(0.62); C586(0.84); C304(0.99); C608(1.09)  LDD0637  [13]
 LDCM0321  AC58 HCT 116 C742(0.74); C608(0.95); C613(0.99); C586(1.04)  LDD0638  [13]
 LDCM0322  AC59 HCT 116 C742(0.62); C304(0.94); C586(0.96); C608(1.03)  LDD0639  [13]
 LDCM0323  AC6 HCT 116 C742(0.56); C304(0.81); C608(0.86); C96(0.96)  LDD0640  [13]
 LDCM0324  AC60 HCT 116 C742(0.72); C608(0.95); C304(0.95); C613(1.00)  LDD0641  [13]
 LDCM0325  AC61 HCT 116 C586(0.84); C742(0.85); C304(0.91); C96(1.11)  LDD0642  [13]
 LDCM0326  AC62 HCT 116 C742(0.84); C586(0.92); C304(0.97); C608(0.99)  LDD0643  [13]
 LDCM0327  AC63 HCT 116 C586(0.69); C742(0.77); C304(1.02); C613(1.09)  LDD0644  [13]
 LDCM0328  AC64 HCT 116 C742(0.74); C304(0.91); C613(0.97); C608(0.99)  LDD0645  [13]
 LDCM0329  AC65 HCT 116 C586(0.81); C608(0.93); C742(0.95); C613(1.00)  LDD0646  [13]
 LDCM0330  AC66 HCT 116 C608(0.87); C586(0.88); C742(0.93); C613(0.94)  LDD0647  [13]
 LDCM0331  AC67 HCT 116 C742(0.65); C586(0.81); C304(0.95); C608(1.14)  LDD0648  [13]
 LDCM0332  AC68 HCT 116 C742(0.67); C304(0.94); C608(1.00); C96(1.03)  LDD0649  [13]
 LDCM0333  AC69 HCT 116 C742(0.69); C608(0.89); C613(0.95); C96(0.96)  LDD0650  [13]
 LDCM0334  AC7 HCT 116 C742(0.72); C304(0.97); C608(1.11); C613(1.21)  LDD0651  [13]
 LDCM0335  AC70 HCT 116 C742(0.61); C613(0.81); C608(0.81); C304(0.85)  LDD0652  [13]
 LDCM0336  AC71 HCT 116 C742(0.79); C608(0.86); C613(0.96); C96(0.98)  LDD0653  [13]
 LDCM0337  AC72 HCT 116 C742(0.70); C608(0.72); C613(0.74); C304(0.90)  LDD0654  [13]
 LDCM0338  AC73 HCT 116 C742(0.67); C613(0.79); C608(0.80); C304(1.01)  LDD0655  [13]
 LDCM0339  AC74 HCT 116 C742(0.72); C608(0.85); C613(0.85); C304(1.18)  LDD0656  [13]
 LDCM0340  AC75 HCT 116 C608(0.76); C742(0.78); C613(0.81); C304(1.16)  LDD0657  [13]
 LDCM0341  AC76 HCT 116 C742(0.77); C608(0.81); C613(0.82); C304(0.93)  LDD0658  [13]
 LDCM0342  AC77 HCT 116 C742(0.66); C608(0.96); C96(0.97); C304(0.98)  LDD0659  [13]
 LDCM0343  AC78 HCT 116 C96(0.87); C742(0.89); C304(0.93); C608(1.09)  LDD0660  [13]
 LDCM0344  AC79 HCT 116 C742(0.82); C608(0.94); C613(0.99); C304(1.06)  LDD0661  [13]
 LDCM0345  AC8 HCT 116 C742(0.64); C608(0.88); C96(0.91); C304(0.93)  LDD0662  [13]
 LDCM0346  AC80 HCT 116 C742(0.70); C608(0.92); C613(0.96); C304(0.99)  LDD0663  [13]
 LDCM0347  AC81 HCT 116 C742(0.85); C96(1.08); C304(1.09); C608(1.27)  LDD0664  [13]
 LDCM0348  AC82 HCT 116 C742(0.80); C608(0.94); C613(0.95); C304(1.13)  LDD0665  [13]
 LDCM0349  AC83 HCT 116 C742(0.49); C586(0.79); C613(0.87); C304(0.88)  LDD0666  [13]
 LDCM0350  AC84 HCT 116 C742(0.45); C613(0.76); C586(0.77); C304(0.84)  LDD0667  [13]
 LDCM0351  AC85 HCT 116 C742(0.76); C304(0.87); C613(0.91); C586(0.93)  LDD0668  [13]
 LDCM0352  AC86 HCT 116 C742(0.61); C304(0.80); C613(0.99); C608(1.06)  LDD0669  [13]
 LDCM0353  AC87 HCT 116 C742(0.92); C304(0.95); C613(1.00); C586(1.05)  LDD0670  [13]
 LDCM0354  AC88 HCT 116 C742(0.58); C304(0.82); C586(0.84); C613(1.01)  LDD0671  [13]
 LDCM0355  AC89 HCT 116 C742(0.48); C304(0.76); C586(0.77); C613(1.02)  LDD0672  [13]
 LDCM0357  AC90 HCT 116 C586(0.89); C613(0.93); C304(0.97); C96(1.10)  LDD0674  [13]
 LDCM0358  AC91 HCT 116 C742(0.50); C304(0.78); C586(0.85); C613(0.97)  LDD0675  [13]
 LDCM0359  AC92 HCT 116 C742(0.45); C304(0.87); C586(0.89); C613(0.97)  LDD0676  [13]
 LDCM0360  AC93 HCT 116 C742(0.68); C304(0.79); C586(0.81); C613(1.00)  LDD0677  [13]
 LDCM0361  AC94 HCT 116 C742(0.81); C304(0.92); C586(0.95); C96(1.11)  LDD0678  [13]
 LDCM0362  AC95 HCT 116 C742(0.88); C586(0.91); C304(0.93); C613(0.98)  LDD0679  [13]
 LDCM0363  AC96 HCT 116 C742(0.64); C304(0.83); C608(1.06); C586(1.09)  LDD0680  [13]
 LDCM0364  AC97 HCT 116 C742(0.43); C304(0.76); C613(0.80); C586(0.80)  LDD0681  [13]
 LDCM0365  AC98 HCT 116 C742(0.38); C608(0.55); C613(0.55); C304(0.60)  LDD0682  [13]
 LDCM0366  AC99 HCT 116 C742(0.61); C304(0.69); C608(0.70); C613(0.70)  LDD0683  [13]
 LDCM0545  Acetamide MDA-MB-231 C742(0.48)  LDD2138  [7]
 LDCM0248  AKOS034007472 HCT 116 C96(0.96); C304(0.92); C608(0.98); C613(1.11)  LDD0565  [13]
 LDCM0356  AKOS034007680 HCT 116 C742(0.94); C608(1.00); C304(1.06); C96(1.08)  LDD0673  [13]
 LDCM0275  AKOS034007705 HCT 116 C742(0.30); C304(0.78); C608(0.97); C613(1.11)  LDD0592  [13]
 LDCM0020  ARS-1620 HCC44 C96(1.14); C608(0.98); C613(0.98)  LDD0078  [13]
 LDCM0199  BPK-21 T cell C96(10.59)  LDD0517  [27]
 LDCM0200  BPK-25 T cell C96(8.30)  LDD0516  [27]
 LDCM0498  BS-3668 MDA-MB-231 C96(0.57)  LDD2091  [7]
 LDCM0108  Chloroacetamide HeLa C96(0.00); C304(0.00); C742(0.00); C608(0.00)  LDD0222  [18]
 LDCM0632  CL-Sc Hep-G2 C304(2.73)  LDD2227  [21]
 LDCM0367  CL1 HCT 116 C608(1.09); C304(1.09); C613(1.18); C586(1.18)  LDD0684  [13]
 LDCM0368  CL10 HCT 116 C742(0.77); C304(0.88); C586(1.08); C608(1.25)  LDD0685  [13]
 LDCM0369  CL100 HCT 116 C613(0.71); C608(0.75); C742(0.82); C96(0.95)  LDD0686  [13]
 LDCM0370  CL101 HCT 116 C742(0.54); C304(0.78); C608(0.98); C613(1.15)  LDD0687  [13]
 LDCM0371  CL102 HCT 116 C742(0.86); C304(0.88); C608(0.91); C613(1.14)  LDD0688  [13]
 LDCM0372  CL103 HCT 116 C742(0.77); C304(1.00); C608(1.01); C613(1.33)  LDD0689  [13]
 LDCM0373  CL104 HCT 116 C742(0.92); C608(0.99); C304(1.01); C613(1.20)  LDD0690  [13]
 LDCM0374  CL105 HCT 116 C586(0.44); C742(0.56); C608(0.82); C613(0.85)  LDD0691  [13]
 LDCM0375  CL106 HCT 116 C742(0.30); C586(0.43); C608(0.84); C613(0.89)  LDD0692  [13]
 LDCM0376  CL107 HCT 116 C742(0.36); C586(0.47); C613(0.71); C608(0.72)  LDD0693  [13]
 LDCM0377  CL108 HCT 116 C742(0.29); C586(0.43); C613(0.67); C608(0.74)  LDD0694  [13]
 LDCM0378  CL109 HCT 116 C742(0.60); C586(0.66); C613(0.84); C608(0.88)  LDD0695  [13]
 LDCM0379  CL11 HCT 116 C304(0.87); C742(0.96); C586(1.00); C613(1.29)  LDD0696  [13]
 LDCM0380  CL110 HCT 116 C742(0.35); C586(0.41); C608(0.92); C613(1.05)  LDD0697  [13]
 LDCM0381  CL111 HCT 116 C586(0.45); C742(0.74); C613(0.85); C608(0.86)  LDD0698  [13]
 LDCM0382  CL112 HCT 116 C613(0.65); C742(0.77); C608(0.79); C304(0.89)  LDD0699  [13]
 LDCM0383  CL113 HCT 116 C613(0.43); C742(0.53); C608(0.58); C304(0.79)  LDD0700  [13]
 LDCM0384  CL114 HCT 116 C613(0.35); C608(0.46); C742(0.81); C304(1.04)  LDD0701  [13]
 LDCM0385  CL115 HCT 116 C613(0.67); C608(0.72); C742(0.77); C304(0.86)  LDD0702  [13]
 LDCM0386  CL116 HCT 116 C304(0.74); C742(0.78); C608(0.92); C613(1.04)  LDD0703  [13]
 LDCM0387  CL117 HCT 116 C304(0.92); C742(0.97); C586(1.07); C613(1.07)  LDD0704  [13]
 LDCM0388  CL118 HCT 116 C304(0.87); C96(1.03); C613(1.27); C742(1.27)  LDD0705  [13]
 LDCM0389  CL119 HCT 116 C304(0.83); C742(1.06); C96(1.09); C608(1.24)  LDD0706  [13]
 LDCM0390  CL12 HCT 116 C742(0.90); C586(0.93); C304(1.07); C608(1.38)  LDD0707  [13]
 LDCM0391  CL120 HCT 116 C304(0.78); C96(1.05); C742(1.20); C613(1.28)  LDD0708  [13]
 LDCM0392  CL121 HCT 116 C586(0.54); C742(0.69); C304(0.77); C96(1.26)  LDD0709  [13]
 LDCM0393  CL122 HCT 116 C586(1.01); C304(1.04); C742(1.07); C96(1.80)  LDD0710  [13]
 LDCM0394  CL123 HCT 116 C742(0.78); C304(0.96); C586(1.14); C96(14.72)  LDD0711  [13]
 LDCM0395  CL124 HCT 116 C586(0.75); C742(0.82); C304(0.94); C96(2.73)  LDD0712  [13]
 LDCM0396  CL125 HCT 116 C586(0.88); C742(0.91); C304(1.07); C96(1.12)  LDD0713  [13]
 LDCM0397  CL126 HCT 116 C742(0.85); C304(0.97); C586(0.98); C96(1.20)  LDD0714  [13]
 LDCM0398  CL127 HCT 116 C742(0.83); C304(0.96); C608(0.99); C586(1.00)  LDD0715  [13]
 LDCM0399  CL128 HCT 116 C742(0.69); C586(0.75); C304(0.93); C96(1.12)  LDD0716  [13]
 LDCM0400  CL13 HCT 116 C586(1.00); C304(1.03); C742(1.12); C96(1.15)  LDD0717  [13]
 LDCM0401  CL14 HCT 116 C742(0.93); C586(1.01); C608(1.16); C304(1.24)  LDD0718  [13]
 LDCM0402  CL15 HCT 116 C586(1.11); C304(1.19); C608(1.22); C742(1.22)  LDD0719  [13]
 LDCM0403  CL16 HCT 116 C742(0.78); C608(0.82); C613(0.83); C304(0.87)  LDD0720  [13]
 LDCM0404  CL17 HCT 116 C742(0.76); C586(0.89); C613(0.90); C608(1.02)  LDD0721  [13]
 LDCM0405  CL18 HCT 116 C613(0.78); C304(0.82); C96(0.88); C608(0.88)  LDD0722  [13]
 LDCM0406  CL19 HCT 116 C742(0.72); C613(0.84); C304(0.85); C608(0.96)  LDD0723  [13]
 LDCM0407  CL2 HCT 116 C304(0.88); C608(1.06); C96(1.08); C586(1.17)  LDD0724  [13]
 LDCM0408  CL20 HCT 116 C742(0.41); C304(0.78); C613(0.88); C608(0.96)  LDD0725  [13]
 LDCM0409  CL21 HCT 116 C742(0.42); C613(0.97); C304(1.02); C608(1.08)  LDD0726  [13]
 LDCM0410  CL22 HCT 116 C742(0.50); C304(0.97); C613(0.97); C608(0.97)  LDD0727  [13]
 LDCM0411  CL23 HCT 116 C742(0.45); C586(0.82); C304(0.96); C96(1.01)  LDD0728  [13]
 LDCM0412  CL24 HCT 116 C742(0.40); C304(0.82); C586(0.97); C608(1.09)  LDD0729  [13]
 LDCM0413  CL25 HCT 116 C96(3.77); C304(0.93); C586(1.13); C608(0.89)  LDD0730  [13]
 LDCM0414  CL26 HCT 116 C96(1.01); C304(0.91); C586(1.12); C608(0.81)  LDD0731  [13]
 LDCM0415  CL27 HCT 116 C96(1.10); C304(0.80); C586(0.94); C608(0.96)  LDD0732  [13]
 LDCM0416  CL28 HCT 116 C96(1.45); C304(0.73); C586(1.20); C608(0.98)  LDD0733  [13]
 LDCM0417  CL29 HCT 116 C96(1.05); C304(0.72); C586(1.12); C608(1.04)  LDD0734  [13]
 LDCM0418  CL3 HCT 116 C96(1.53); C304(1.09); C586(0.85); C608(1.13)  LDD0735  [13]
 LDCM0419  CL30 HCT 116 C96(1.01); C304(0.87); C586(1.12); C608(0.94)  LDD0736  [13]
 LDCM0420  CL31 HCT 116 C96(1.65); C304(1.01); C586(0.91); C608(1.17)  LDD0737  [13]
 LDCM0421  CL32 HCT 116 C96(1.20); C304(1.08); C586(1.38); C608(1.00)  LDD0738  [13]
 LDCM0422  CL33 HCT 116 C96(8.68); C304(0.92); C586(1.66); C608(0.82)  LDD0739  [13]
 LDCM0423  CL34 HCT 116 C96(2.18); C304(1.02); C586(0.98); C608(1.00)  LDD0740  [13]
 LDCM0424  CL35 HCT 116 C96(0.93); C304(1.05); C586(0.90); C608(0.99)  LDD0741  [13]
 LDCM0425  CL36 HCT 116 C96(1.25); C304(1.21); C586(1.11); C608(0.82)  LDD0742  [13]
 LDCM0426  CL37 HCT 116 C96(1.68); C304(1.14); C586(1.00); C608(1.06)  LDD0743  [13]
 LDCM0428  CL39 HCT 116 C96(1.49); C304(1.06); C586(0.90); C608(0.93)  LDD0745  [13]
 LDCM0429  CL4 HCT 116 C96(1.82); C304(1.11); C586(1.01); C608(0.94)  LDD0746  [13]
 LDCM0430  CL40 HCT 116 C96(0.98); C304(1.03); C586(1.44); C608(0.97)  LDD0747  [13]
 LDCM0431  CL41 HCT 116 C96(1.34); C304(1.04); C586(0.84); C608(1.03)  LDD0748  [13]
 LDCM0432  CL42 HCT 116 C96(2.64); C304(1.31); C586(0.82); C608(0.90)  LDD0749  [13]
 LDCM0433  CL43 HCT 116 C96(1.08); C304(1.01); C586(0.83); C608(0.98)  LDD0750  [13]
 LDCM0434  CL44 HCT 116 C96(0.99); C304(1.09); C586(1.17); C608(1.13)  LDD0751  [13]
 LDCM0435  CL45 HCT 116 C96(1.70); C304(0.98); C586(1.16); C608(0.99)  LDD0752  [13]
 LDCM0436  CL46 HCT 116 C96(1.34); C304(1.12); C586(1.00); C608(1.26)  LDD0753  [13]
 LDCM0437  CL47 HCT 116 C96(1.10); C304(1.16); C586(1.01); C608(1.22)  LDD0754  [13]
 LDCM0438  CL48 HCT 116 C96(1.50); C304(1.23); C586(1.07); C608(1.21)  LDD0755  [13]
 LDCM0439  CL49 HCT 116 C96(5.70); C304(1.08); C586(1.12); C608(1.56)  LDD0756  [13]
 LDCM0440  CL5 HCT 116 C96(1.14); C304(0.99); C586(1.05); C608(1.02)  LDD0757  [13]
 LDCM0441  CL50 HCT 116 C96(1.77); C304(1.21); C586(1.07); C608(1.40)  LDD0758  [13]
 LDCM0442  CL51 HCT 116 C96(3.07); C304(1.08); C586(1.14); C608(1.23)  LDD0759  [13]
 LDCM0443  CL52 HCT 116 C96(2.44); C304(0.99); C586(0.99); C608(1.12)  LDD0760  [13]
 LDCM0444  CL53 HCT 116 C96(2.22); C304(1.07); C586(1.28); C608(0.90)  LDD0761  [13]
 LDCM0445  CL54 HCT 116 C96(3.43); C304(0.98); C586(0.92); C608(1.10)  LDD0762  [13]
 LDCM0446  CL55 HCT 116 C96(1.70); C304(1.12); C586(1.12); C608(1.07)  LDD0763  [13]
 LDCM0447  CL56 HCT 116 C96(1.02); C304(1.09); C586(1.05); C608(1.12)  LDD0764  [13]
 LDCM0448  CL57 HCT 116 C96(1.07); C304(1.06); C586(1.28); C608(1.26)  LDD0765  [13]
 LDCM0449  CL58 HCT 116 C96(1.14); C304(1.09); C586(1.07); C608(1.28)  LDD0766  [13]
 LDCM0450  CL59 HCT 116 C96(1.04); C304(1.02); C586(1.11); C608(1.16)  LDD0767  [13]
 LDCM0451  CL6 HCT 116 C96(1.89); C304(1.05); C586(1.11); C608(1.12)  LDD0768  [13]
 LDCM0452  CL60 HCT 116 C96(1.27); C304(1.06); C586(1.15); C608(1.13)  LDD0769  [13]
 LDCM0453  CL61 HCT 116 C96(1.12); C304(1.11); C586(0.83); C608(0.95)  LDD0770  [13]
 LDCM0454  CL62 HCT 116 C96(1.12); C304(1.10); C586(0.78); C608(0.91)  LDD0771  [13]
 LDCM0455  CL63 HCT 116 C96(2.39); C304(1.31); C586(0.89); C608(1.07)  LDD0772  [13]
 LDCM0456  CL64 HCT 116 C96(3.46); C304(1.10); C586(0.79); C608(1.26)  LDD0773  [13]
 LDCM0457  CL65 HCT 116 C96(1.25); C304(1.51); C586(0.93); C608(1.36)  LDD0774  [13]
 LDCM0458  CL66 HCT 116 C96(1.20); C304(1.21); C586(0.84); C608(1.26)  LDD0775  [13]
 LDCM0459  CL67 HCT 116 C96(1.07); C304(1.20); C586(0.73); C608(1.17)  LDD0776  [13]
 LDCM0460  CL68 HCT 116 C96(1.21); C304(1.30); C586(0.72); C608(1.01)  LDD0777  [13]
 LDCM0461  CL69 HCT 116 C96(1.65); C304(1.09); C586(0.90); C608(1.03)  LDD0778  [13]
 LDCM0462  CL7 HCT 116 C96(1.71); C304(1.09); C586(1.05); C608(1.24)  LDD0779  [13]
 LDCM0463  CL70 HCT 116 C96(1.20); C304(1.08); C586(0.69); C608(1.20)  LDD0780  [13]
 LDCM0464  CL71 HCT 116 C96(1.28); C304(1.24); C586(0.65); C608(1.25)  LDD0781  [13]
 LDCM0465  CL72 HCT 116 C96(1.08); C304(1.04); C586(0.75); C608(1.14)  LDD0782  [13]
 LDCM0466  CL73 HCT 116 C96(1.74); C304(1.24); C586(0.72); C608(1.23)  LDD0783  [13]
 LDCM0467  CL74 HCT 116 C96(1.15); C304(1.22); C586(0.75); C608(1.11)  LDD0784  [13]
 LDCM0469  CL76 HCT 116 C96(1.09); C304(1.01); C586(0.96); C608(0.96)  LDD0786  [13]
 LDCM0470  CL77 HCT 116 C96(1.86); C304(1.13); C586(0.93); C608(1.10)  LDD0787  [13]
 LDCM0471  CL78 HCT 116 C96(1.13); C304(0.97); C586(0.86); C608(1.45)  LDD0788  [13]
 LDCM0472  CL79 HCT 116 C96(0.89); C304(0.99); C586(0.97); C608(1.22)  LDD0789  [13]
 LDCM0473  CL8 HCT 116 C96(1.87); C304(0.84); C586(0.94); C608(0.81)  LDD0790  [13]
 LDCM0474  CL80 HCT 116 C96(1.06); C304(1.05); C586(0.93); C608(1.51)  LDD0791  [13]
 LDCM0475  CL81 HCT 116 C96(1.07); C304(1.14); C586(0.91); C608(1.28)  LDD0792  [13]
 LDCM0476  CL82 HCT 116 C96(1.47); C304(1.13); C586(0.84); C608(1.36)  LDD0793  [13]
 LDCM0477  CL83 HCT 116 C96(5.21); C304(1.07); C586(0.83); C608(1.26)  LDD0794  [13]
 LDCM0478  CL84 HCT 116 C96(3.62); C304(1.08); C586(1.04); C608(1.09)  LDD0795  [13]
 LDCM0479  CL85 HCT 116 C96(1.22); C304(1.10); C586(0.87); C608(1.31)  LDD0796  [13]
 LDCM0480  CL86 HCT 116 C96(1.04); C304(1.15); C586(0.86); C608(1.03)  LDD0797  [13]
 LDCM0481  CL87 HCT 116 C96(1.14); C304(1.10); C586(0.90); C608(1.28)  LDD0798  [13]
 LDCM0482  CL88 HCT 116 C96(1.00); C304(1.05); C586(0.94); C608(1.18)  LDD0799  [13]
 LDCM0483  CL89 HCT 116 C96(1.09); C304(1.16); C586(0.97); C608(1.30)  LDD0800  [13]
 LDCM0484  CL9 HCT 116 C96(1.29); C304(1.02); C586(1.06); C608(1.08)  LDD0801  [13]
 LDCM0485  CL90 HCT 116 C96(5.02); C304(1.47); C586(0.88); C608(1.03)  LDD0802  [13]
 LDCM0486  CL91 HCT 116 C96(1.11); C304(1.00); C586(1.23); C608(0.82)  LDD0803  [13]
 LDCM0487  CL92 HCT 116 C96(1.02); C304(1.14); C586(0.87); C608(0.94)  LDD0804  [13]
 LDCM0488  CL93 HCT 116 C96(0.83); C304(1.10); C586(1.07); C608(0.89)  LDD0805  [13]
 LDCM0489  CL94 HCT 116 C96(1.21); C304(0.95); C586(0.89); C608(0.76)  LDD0806  [13]
 LDCM0490  CL95 HCT 116 C96(3.10); C304(1.15); C586(1.31); C608(0.65)  LDD0807  [13]
 LDCM0491  CL96 HCT 116 C96(1.16); C304(1.03); C586(1.39); C608(0.84)  LDD0808  [13]
 LDCM0492  CL97 HCT 116 C96(1.79); C304(1.10); C586(1.33); C608(0.83)  LDD0809  [13]
 LDCM0493  CL98 HCT 116 C96(0.99); C304(0.94); C586(1.50); C608(0.79)  LDD0810  [13]
 LDCM0494  CL99 HCT 116 C96(0.90); C304(0.93); C586(1.39); C608(0.73)  LDD0811  [13]
 LDCM0495  E2913 HEK-293T C742(0.95); C586(1.06); C659(1.10); C304(0.83)  LDD1698  [28]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C742(3.32)  LDD1702  [7]
 LDCM0175  Ethacrynic acid HeLa C304(2.54)  LDD2210  [12]
 LDCM0202  EV-93 T cell C96(20.00)  LDD0527  [27]
 LDCM0203  EV-96 T cell C96(4.27)  LDD0523  [27]
 LDCM0625  F8 Ramos C96(1.52); C304(1.46)  LDD2187  [29]
 LDCM0572  Fragment10 Ramos 2.38  LDD2189  [29]
 LDCM0573  Fragment11 Ramos 1.24; C96(20.00); C304(13.15)  LDD2190  [29]
 LDCM0574  Fragment12 Ramos 2.56  LDD2191  [29]
 LDCM0575  Fragment13 Ramos C96(1.38); C304(1.58)  LDD2192  [29]
 LDCM0576  Fragment14 Ramos 1.32; C96(1.71)  LDD2193  [29]
 LDCM0580  Fragment21 Ramos C96(1.12); C304(1.48)  LDD2195  [29]
 LDCM0582  Fragment23 Ramos 0.87; C96(0.97); C304(0.65)  LDD2196  [29]
 LDCM0578  Fragment27 Ramos C96(1.00); C304(0.68)  LDD2197  [29]
 LDCM0586  Fragment28 Ramos C96(1.17); C304(0.77)  LDD2198  [29]
 LDCM0588  Fragment30 Ramos C96(2.13); C304(1.87)  LDD2199  [29]
 LDCM0589  Fragment31 Ramos C96(1.51); C304(0.82)  LDD2200  [29]
 LDCM0590  Fragment32 Ramos C96(10.83)  LDD2201  [29]
 LDCM0468  Fragment33 HCT 116 C96(1.10); C304(1.05); C586(0.87); C608(1.15)  LDD0785  [13]
 LDCM0596  Fragment38 Ramos 0.47; C96(2.91); C304(0.72)  LDD2203  [29]
 LDCM0566  Fragment4 Ramos 1.24  LDD2184  [29]
 LDCM0427  Fragment51 HCT 116 C96(1.36); C304(1.19); C586(1.18); C608(0.67)  LDD0744  [13]
 LDCM0610  Fragment52 Ramos C96(2.88); C304(1.66)  LDD2204  [29]
 LDCM0614  Fragment56 Ramos C96(1.15); C304(0.78)  LDD2205  [29]
 LDCM0616  Fragment61 Jurkat _(20.00)  LDD1489  [10]
 LDCM0615  Fragment63-R Jurkat _(20.00)  LDD1487  [10]
 LDCM0617  Fragment63-S Jurkat _(20.00)  LDD1490  [10]
 LDCM0569  Fragment7 Jurkat _(11.43)  LDD1485  [10]
 LDCM0149  GA MCF-7 C96(3.16)  LDD0379  [30]
 LDCM0015  HNE MDA-MB-231 C304(1.18); C96(1.19)  LDD0346  [29]
 LDCM0107  IAA HeLa C304(0.00); C742(0.00); H25(0.00); C613(0.00)  LDD0221  [18]
 LDCM0179  JZ128 PC-3 C96(0.00); C304(0.00)  LDD0462  [8]
 LDCM0022  KB02 HEK-293T C742(0.97); C96(0.86); C586(0.92); C659(1.01)  LDD1492  [28]
 LDCM0023  KB03 Jurkat C96(4.55)  LDD0315  [31]
 LDCM0024  KB05 COLO792 C742(1.33); C659(2.72)  LDD3310  [32]
 LDCM0169  KB63 Ramos 20.00  LDD0432  [33]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C742(0.62)  LDD2121  [7]
 LDCM0109  NEM HeLa H327(0.00); H25(0.00); H445(0.00); H748(0.00)  LDD0223  [18]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C742(0.99)  LDD2089  [7]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C742(1.04)  LDD2093  [7]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C742(0.65)  LDD2094  [7]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C742(0.94)  LDD2098  [7]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C742(1.16); C96(0.90)  LDD2099  [7]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C742(1.49)  LDD2100  [7]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C742(0.62); C96(1.08)  LDD2101  [7]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C742(0.81)  LDD2104  [7]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C742(1.12)  LDD2105  [7]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C742(1.34)  LDD2107  [7]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C742(0.76)  LDD2108  [7]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C742(0.98); C96(0.87)  LDD2109  [7]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C742(1.52); C96(0.63)  LDD2111  [7]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C742(0.72)  LDD2114  [7]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C742(1.80)  LDD2119  [7]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C742(1.03); C96(1.02)  LDD2123  [7]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C742(1.04); C96(0.90)  LDD2125  [7]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C742(1.43)  LDD2127  [7]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C742(1.14)  LDD2129  [7]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C742(0.93)  LDD2135  [7]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C742(1.40); C96(1.26); C613(1.23)  LDD2136  [7]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C742(1.36); C96(0.92)  LDD2137  [7]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C742(2.01)  LDD1700  [7]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C742(1.10)  LDD2140  [7]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C742(0.94)  LDD2141  [7]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C742(2.58)  LDD2144  [7]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C742(1.14)  LDD2146  [7]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C742(0.55); C96(0.39)  LDD2150  [7]
 LDCM0627  NUDT7-COV-1 HEK-293T C96(0.07)  LDD2206  [34]
 LDCM0628  OTUB2-COV-1 HEK-293T C96(0.51)  LDD2207  [34]
 LDCM0131  RA190 MM1.R 5.31  LDD0299  [11]
 LDCM0003  Sulforaphane MDA-MB-231 1.30  LDD0160  [9]
 LDCM0021  THZ1 HCT 116 C96(1.04); C304(1.08)  LDD2173  [13]
 LDCM0112  W16 Hep-G2 C96(0.82)  LDD0239  [19]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Approved
Click To Hide/Show 3 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Glyburide Small molecular drug DB01016
Levocarnitine Small molecular drug DB00583
Perhexiline Small molecular drug DB01074

References

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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD006279
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD029255
16 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007570
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Mass spectrometry data entry: PXD044402
29 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD047840
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