Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | IA-alkyne | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 100 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
TMT
|
|||||
| Competitor Name | BPK-25 | Competitor Info | ||||
| Competitor Concentration | 10 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Cell lysate | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cell lysate (T cell) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP13219 | GTPase IMAP family member 2 (GIMAP2) | C261 | 20.0 | |||
| LDTP09598 | Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) | C207 | 20.0 | |||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | C238 | 17.6 | |||
| LDTP00577 | Dihydroxyacetone phosphate acyltransferase (GNPAT) | C54 | 11.8 | |||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | C282 | 11.1 | |||
| LDTP12835 | Large ribosomal subunit protein mL39 (MRPL39) | C133 | 10.1 | |||
| LDTP12040 | Prostaglandin E synthase 2 (PTGES2) | C110 | 10.0 | |||
| LDTP04565 | Methionine aminopeptidase 1 (METAP1) | C292 | 9.0 | |||
| LDTP04358 | Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) | C96 | 8.3 | |||
| LDTP09841 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (ALG3) | C21 | 7.1 | |||
| LDTP05409 | Antigen peptide transporter 2 (TAP2) | C641 | 6.8 | |||
| LDTP12459 | Baculoviral IAP repeat-containing protein 6 (BIRC6) | C2123 | 6.7 | |||
| LDTP09344 | Prostamide/prostaglandin F synthase (PRXL2B) | C44 | 6.2 | |||
| LDTP06787 | Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) | C265 | 6.0 | |||
| LDTP04573 | LIM domain kinase 1 (LIMK1) | C349 | 4.1 | |||
| LDTP11127 | ADP-dependent glucokinase (ADPGK) | C40 | 4.0 | |||
Transporter and channel
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP05252 | Clathrin heavy chain 1 (CLTC) | C870 | 7.7 | |||
| LDTP13696 | AP-4 complex subunit epsilon-1 (AP4E1) | C1119 | 7.3 | |||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | C210, C227 | 5.1 | |||
| LDTP12548 | Phospholipid scramblase 3 (PLSCR3) | C125, C126 | 4.8 | |||
Immunoglobulin
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP00671 | Tapasin (TAPBP) | C440 | 4.5 | |||
Other
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP05257 | Receptor expression-enhancing protein 5 (REEP5) | C18 | 20.0 | |||
| LDTP09399 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1) | C1266 | 9.5 | |||
| LDTP12412 | Reticulon-4 (RTN4) | C1101 | 9.1 | |||
| LDTP17715 | S1 RNA-binding domain-containing protein 1 (SRBD1) | C294 | 8.4 | |||
| LDTP19719 | Solute carrier family 66 member 3 (SLC66A3) | C135 | 8.4 | |||
| LDTP18484 | Torsin-4A (TOR4A) | C21 | 7.7 | |||
| LDTP06250 | Proteasome activator complex subunit 4 (PSME4) | C1000, C1001 | 4.1 | |||
| LDTP13090 | UV radiation resistance-associated gene protein (UVRAG) | C239 | 4.0 | |||