Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C390  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 170 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05905  Acid ceramidase (ASAH1) 99.7
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 99.7
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 99.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 99.7
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 99.7
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 99.7
 LDTP03540  Heme oxygenase 2 (HMOX2) 99.7
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 99.7
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 99.7
 LDTP02539  Lysosomal acid phosphatase (ACP2) 99.7
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 99.7
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 99.7
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 99.7
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 99.7
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 99.7
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 97.7
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 96.3
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 93.7
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 90.5
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 89.9
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 86.8
 LDTP10020  Ras-related protein Rab-24 (RAB24) 85.6
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 81.6
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 81.0
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 75.6
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 75.6
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 75.1
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 74.5
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 74.5
 LDTP01803  Adenosine deaminase (ADA) 70.0
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 67.6
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 62.7
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 58.5
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 57.3
 LDTP03145  Catechol O-methyltransferase (COMT) 57.3
 LDTP02505  Lysosomal protective protein (CTSA) 57.3
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 56.9
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 56.5
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 56.1
 LDTP00783  Beta-1,4-glucuronyltransferase 1 (B4GAT1) 55.7
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 55.7
 LDTP11127  ADP-dependent glucokinase (ADPGK) 55.3
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 53.8
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 53.8
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 53.4
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 53.4
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 53.1
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 51.6
 LDTP02359  Heme oxygenase 1 (HMOX1) 50.9
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 49.9
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 49.5
 LDTP02837  Beta-galactosidase (GLB1) 49.2
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 48.8
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 48.8
 LDTP16040  Glyoxalase domain-containing protein 4 (GLOD4) 46.9
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 46.2
 LDTP03419  Proteasome subunit beta type-5 (PSMB5) 46.2
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 45.9
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 45.6
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 45.3
 LDTP03816  Oxidized purine nucleoside triphosphate hydrolase (NUDT1) 43.4
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 43.1
 LDTP01665  Geranylgeranyl pyrophosphate synthase (GGPS1) 42.5
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 41.6
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 41.6
 LDTP07931  Heme A synthase COX15 (COX15) 41.1
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 40.8
 LDTP02141  Alpha-galactosidase A (GLA) 39.4
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 39.4
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 39.4
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 38.6
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 38.3
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 38.1
 LDTP06142  Squalene monooxygenase (SQLE) 38.1
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 37.8
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 37.5
 LDTP09251  Atlastin-2 (ATL2) 37.3
 LDTP11284  Phosphatidylserine synthase 2 (PTDSS2) 36.8
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 35.5
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 35.3
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 34.5
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 34.1
 LDTP05638  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) 34.1
 LDTP03787  Choline kinase alpha (CHKA) 32.9
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 32.0
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 31.8
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 31.8
 LDTP12886  Glycerophosphodiester phosphodiesterase 1 (GDE1) 31.8
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 31.6
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 30.7
 LDTP03842  Squalene synthase (FDFT1) 30.7
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 30.5
 LDTP10249  Metalloendopeptidase OMA1, mitochondrial (OMA1) 30.3
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 30.1
 LDTP11187  COP9 signalosome complex subunit 4 (COPS4) 30.1
 LDTP03858  Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) 30.1
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 29.9
 LDTP06750  Prolyl 3-hydroxylase 1 (P3H1) 29.9
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 29.4
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 29.4
 LDTP02006  Tissue alpha-L-fucosidase (FUCA1) 29.4
 LDTP11016  Dual specificity protein phosphatase 9 (DUSP9) 29.2
 LDTP02799  N-acetylglucosamine-6-sulfatase (GNS) 28.8
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 28.6
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 28.6
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 28.4
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 28.4
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 28.2
 LDTP05724  Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) 28.1
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 28.1
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 27.5
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 27.3
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 27.3
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 27.1
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 26.9
 LDTP05337  Dihydroorotate dehydrogenase (quinone), mitochondrial (DHODH) 26.7
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 26.7
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 26.7
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 26.4
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 26.2
 LDTP10530  Beta-1,3-galactosyltransferase 6 (B3GALT6) 26.2
 LDTP10583  E3 SUMO-protein ligase NSE2 (NSMCE2) 25.8
 LDTP05228  Calcium-transporting ATPase type 2C member 1 (ATP2C1) 25.6
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 25.6
 LDTP02757  Cytochrome b-c1 complex subunit 7 (UQCRB) 25.5
 LDTP01515  NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) 25.5
 LDTP11994  Palmitoyltransferase ZDHHC6 (ZDHHC6) 25.3
 LDTP10322  Abasic site processing protein HMCES (HMCES) 25.1
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 25.1
 LDTP11215  Plasma alpha-L-fucosidase (FUCA2) 25.1
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 24.9
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 24.8
 LDTP01769  Dihydrofolate reductase (DHFR) 24.4
 LDTP00316  Ribonuclease T2 (RNASET2) 24.3
 LDTP10432  ATP synthase membrane subunit K, mitochondrial (ATP5MK) 23.9
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 23.8
 LDTP11733  Ras-related protein Rab-1B (RAB1B) 23.8
 LDTP06986  Rab-like protein 3 (RABL3) 23.6
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 23.6
 LDTP04531  Hexokinase-2 (HK2) 23.4
 LDTP11437  Peroxisomal trans-2-enoyl-CoA reductase (PECR) 23.4
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 23.3
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 23.3
 LDTP00400  Torsin-1B (TOR1B) 23.1
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 22.9
 LDTP11259  Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) 22.8
 LDTP01329  Lathosterol oxidase (SC5D) 22.6
 LDTP02260  Beta-glucuronidase (GUSB) 22.3
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD) 22.3
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 22.2
 LDTP12002  Alpha-1,2-mannosyltransferase ALG9 (ALG9) 22.0
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 22.0
 LDTP02486  Lysosomal alpha-glucosidase (GAA) 21.9
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 21.7
 LDTP12679  Trimethyllysine dioxygenase, mitochondrial (TMLHE) 21.7
 LDTP01514  NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) 21.6
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 21.4
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 21.3
 LDTP03024  Plasma membrane calcium-transporting ATPase 1 (ATP2B1) 21.1
 LDTP11535  Ras-related protein Rab-34 (RAB34) 21.1
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 21.0
 LDTP13989  Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) 20.8
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 20.8
 LDTP05422  Copper-transporting ATPase 1 (ATP7A) 20.7
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 20.7
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 20.5
 LDTP01372  Carboxypeptidase D (CPD) 20.5
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 20.5
 LDTP09835  GPI-anchor transamidase (PIGK) 20.5
Transporter and channel
Click to Show/Hide to Show 109 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 99.7
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 99.7
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 99.7
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 99.7
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 99.7
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 99.7
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 99.7
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 99.7
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 99.7
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 99.7
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 99.7
 LDTP16813  Tetraspanin-3 (TSPAN3) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP15481  Transmembrane protein 87A (TMEM87A) 99.7
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 99.7
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 99.7
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 99.7
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 95.0
 LDTP05900  Metaxin-1 (MTX1) 93.1
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 84.4
 LDTP01804  ATP synthase subunit a (MT-ATP6) 82.1
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 82.1
 LDTP15948  Transmembrane protein 126A (TMEM126A) 77.7
 LDTP03064  Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) 76.1
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 71.0
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 70.5
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 64.4
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 63.1
 LDTP09288  Vang-like protein 1 (VANGL1) 61.8
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 61.4
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 54.6
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 54.6
 LDTP10065  Transmembrane protein 230 (TMEM230) 54.2
 LDTP07236  Protein GPR107 (GPR107) 50.9
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 49.2
 LDTP07583  Transmembrane protein 65 (TMEM65) 48.2
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 47.8
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 47.2
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 45.6
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 44.9
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 44.6
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 43.1
 LDTP13320  Prenylated Rab acceptor protein 1 (RABAC1) 41.1
 LDTP11250  MICOS complex subunit MIC26 (APOO) 38.3
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 38.1
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 37.3
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 35.5
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 35.0
 LDTP12809  Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) 34.3
 LDTP06499  V-type proton ATPase subunit S1 (ATP6AP1) 34.1
 LDTP01043  Sorting nexin-2 (SNX2) 33.4
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 32.7
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 32.4
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 31.6
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 31.3
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 30.9
 LDTP08469  Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) 30.3
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 30.3
 LDTP02655  Lysosome-associated membrane glycoprotein 2 (LAMP2) 30.1
 LDTP14174  Sorting nexin-5 (SNX5) 29.9
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 29.9
 LDTP13823  Mitochondrial chaperone BCS1 (BCS1L) 29.4
 LDTP01380  Wolframin (WFS1) 29.0
 LDTP12704  Anoctamin-10 (ANO10) 28.1
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 27.5
 LDTP10343  Vacuole membrane protein 1 (VMP1) 27.3
 LDTP06581  Occludin (OCLN) 27.1
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 26.9
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 26.7
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 26.5
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 26.4
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 26.2
 LDTP00592  Surfeit locus protein 4 (SURF4) 26.0
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 25.5
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 25.3
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 24.8
 LDTP07058  Transmembrane protein 201 (TMEM201) 24.6
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 24.4
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 24.3
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 23.8
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 23.8
 LDTP03405  Calnexin (CANX) 23.6
 LDTP10036  BOS complex subunit NCLN (NCLN) 23.3
 LDTP01455  Erlin-2 (ERLIN2) 23.3
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 23.3
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 23.1
 LDTP03546  Translocator protein (TSPO) 23.1
 LDTP11213  Nucleoporin NDC1 (NDC1) 22.9
 LDTP03061  Cation-dependent mannose-6-phosphate receptor (M6PR) 22.8
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 22.6
 LDTP11041  Calcium uptake protein 1, mitochondrial (MICU1) 22.6
 LDTP07667  Transmembrane protein 205 (TMEM205) 22.6
 LDTP07531  Sideroflexin-4 (SFXN4) 22.3
 LDTP01217  Metaxin-2 (MTX2) 22.2
 LDTP13953  Endophilin-B1 (SH3GLB1) 22.0
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 21.9
 LDTP11245  Derlin-1 (DERL1) 21.7
 LDTP06039  Dystroglycan 1 (DAG1) 21.7
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 21.7
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 21.7
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 21.6
 LDTP04501  Importin subunit alpha-1 (KPNA2) 21.4
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 21.1
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 21.1
 LDTP08633  Transmembrane protein 192 (TMEM192) 21.1
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 20.8
Transcription factor
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 47.2
 LDTP15183  NF-X1-type zinc finger protein NFXL1 (NFXL1) 27.5
Immunoglobulin
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03772  Basigin (BSG) 41.9
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 31.8
 LDTP05085  Coxsackievirus and adenovirus receptor (CXADR) 24.3
 LDTP02491  HLA class I histocompatibility antigen, C alpha chain (HLA-C) 23.8
Other
Click to Show/Hide to Show 125 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 99.7
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 99.7
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP05375  Nucleobindin-1 (NUCB1) 99.7
 LDTP05160  Nucleobindin-2 (NUCB2) 99.7
 LDTP18883  Protein CEBPZOS (CEBPZOS) 99.7
 LDTP10056  Protein FAM162A (FAM162A) 99.7
 LDTP01167  Reticulon-2 (RTN2) 99.7
 LDTP13086  Syntaxin-18 (STX18) 99.7
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 99.7
 LDTP14458  Tetraspanin-6 (TSPAN6) 97.0
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 93.7
 LDTP10113  Mitochondrial import receptor subunit TOM6 homolog (TOMM6) 91.1
 LDTP16006  Optic atrophy 3 protein (OPA3) 88.0
 LDTP01522  Reticulon-3 (RTN3) 82.1
 LDTP13630  Neudesin (NENF) 76.1
 LDTP02927  Ganglioside GM2 activator (GM2A) 75.6
 LDTP12412  Reticulon-4 (RTN4) 75.1
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 73.5
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 67.6
 LDTP00986  Syntaxin-10 (STX10) 65.3
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 63.1
 LDTP06097  Reticulocalbin-2 (RCN2) 61.4
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 55.7
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 52.0
 LDTP19963  TraB domain-containing protein (TRABD) 51.6
 LDTP05558  Galectin-3-binding protein (LGALS3BP) 51.3
 LDTP09773  Protein FAM3C (FAM3C) 51.3
 LDTP16080  Protein FAM114A2 (FAM114A2) 49.9
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 48.5
 LDTP14259  Testis-expressed protein 264 (TEX264) 48.5
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 45.6
 LDTP00632  Syntaxin-7 (STX7) 45.3
 LDTP13802  DNA replication complex GINS protein PSF2 (GINS2) 44.3
 LDTP15398  Protein FAM177A1 (FAM177A1) 44.0
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 43.1
 LDTP10924  Prohibitin-2 (PHB2) 41.9
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 41.6
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 41.4
 LDTP09069  Kinetochore protein Spc24 (SPC24) 41.1
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 41.1
 LDTP04356  Emerin (EMD) 40.8
 LDTP08594  Negative elongation factor C/D (NELFCD) 40.8
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 40.2
 LDTP05226  RNA-binding protein 3 (RBM3) 40.2
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 38.3
 LDTP15793  Protein FAM210A (FAM210A) 38.3
 LDTP09787  Nicastrin (NCSTN) 37.0
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 37.0
 LDTP08682  Ankyrin repeat domain-containing protein 13A (ANKRD13A) 36.3
 LDTP12623  Zinc finger CCHC domain-containing protein 3 (ZCCHC3) 35.0
 LDTP12891  Glycolipid transfer protein (GLTP) 34.5
 LDTP06948  Protein YIF1B (YIF1B) 34.5
 LDTP10452  Conserved oligomeric Golgi complex subunit 3 (COG3) 34.3
 LDTP02180  Neurofilament light polypeptide (NEFL) 34.3
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 34.3
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 32.9
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 32.7
 LDTP08000  Dymeclin (DYM) 32.7
 LDTP08224  Protein LYRIC (MTDH) 32.4
 LDTP02205  Tubulin beta chain (TUBB) 32.0
 LDTP13114  C-type mannose receptor 2 (MRC2) 31.8
 LDTP01661  Synaptosomal-associated protein 29 (SNAP29) 31.8
 LDTP01359  Dynactin subunit 3 (DCTN3) 31.3
 LDTP00859  Synaptogyrin-2 (SYNGR2) 31.3
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 31.1
 LDTP01494  Protein YIF1A (YIF1A) 30.9
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 30.7
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 30.5
 LDTP12192  Kinetochore protein Spc25 (SPC25) 30.3
 LDTP08606  Nurim (NRM) 30.3
 LDTP05960  Trophoblast glycoprotein (TPBG) 30.3
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 29.7
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 29.4
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 29.2
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 29.0
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 28.6
 LDTP00105  Protein unc-119 homolog B (UNC119B) 28.6
 LDTP02297  Vimentin (VIM) 28.6
 LDTP02913  Desmin (DES) 28.4
 LDTP05076  Tubulin beta-4B chain (TUBB4B) 28.4
 LDTP01652  Centrosomal protein 43 (CEP43) 27.7
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 27.3
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 27.3
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 26.9
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 26.7
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 26.5
 LDTP05643  Sterol regulatory element-binding protein cleavage-activating protein (SCAP) 26.0
 LDTP05277  Protein SET (SET) 25.8
 LDTP13273  Ubiquilin-2 (UBQLN2) 25.5
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1) 25.3
 LDTP03926  Centrin-2 (CETN2) 24.6
 LDTP06022  Cold-inducible RNA-binding protein (CIRBP) 24.6
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 24.6
 LDTP13913  Inner nuclear membrane protein Man1 (LEMD3) 24.6
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 24.4
 LDTP11870  BolA-like protein 2 (BOLA2; BOLA2B) 23.9
 LDTP18467  LYR motif-containing protein 2 (LYRM2) 23.9
 LDTP12726  PIH1 domain-containing protein 1 (PIH1D1) 23.9
 LDTP09881  TATA-binding protein-associated factor 2N (TAF15) 23.4
 LDTP11670  Mitochondrial fission factor (MFF) 23.3
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 23.3
 LDTP10849  Regulator of microtubule dynamics protein 3 (RMDN3) 23.1
 LDTP00887  Calumenin (CALU) 22.9
 LDTP18134  Protein CUSTOS (CUSTOS) 22.8
 LDTP14792  Small ribosomal subunit protein uS9m (MRPS9) 22.6
 LDTP06373  Mitochondrial import receptor subunit TOM20 homolog (TOMM20) 22.5
 LDTP05998  Tubulin beta-2A chain (TUBB2A) 22.3
 LDTP11277  Tubulin beta-2B chain (TUBB2B) 22.2
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 22.0
 LDTP04703  Tumor protein D52 (TPD52) 22.0
 LDTP20361  Coiled-coil domain-containing protein 127 (CCDC127) 21.9
 LDTP09410  Protein bicaudal D homolog 2 (BICD2) 21.7
 LDTP13019  Vacuolar protein sorting-associated protein 18 homolog (VPS18) 21.7
 LDTP06515  Coiled-coil domain-containing protein 6 (CCDC6) 21.6
 LDTP11233  Tubulin beta-6 chain (TUBB6) 21.6
 LDTP03465  General transcription factor IIE subunit 1 (GTF2E1) 21.4
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 21.4
 LDTP05922  Dynactin subunit 2 (DCTN2) 21.3
 LDTP09920  Golgi apparatus protein 1 (GLG1) 21.3
 LDTP03850  RNA-binding motif protein, X chromosome (RBMX) 21.1
 LDTP11379  TBC1 domain family member 10A (TBC1D10A) 20.8
 LDTP14277  Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) 20.5

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587