Details of the Target

General Information of Target

Target ID LDTP03465
Target Name General transcription factor IIE subunit 1 (GTF2E1)
Gene Name GTF2E1
Gene ID 2960
Synonyms
TF2E1; General transcription factor IIE subunit 1; General transcription factor IIE 56 kDa subunit; Transcription initiation factor IIE subunit alpha; TFIIE-alpha
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADPDVLTEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLR
SVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERD
STNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARF
NEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDHAATTAGAASLAGGHHREAWA
TKGPSYEDLYTQNVVINMDDQEDLHRASLEGKSAKERPIWLRESTVQGAYGSEDMKEGGI
DMDAFQEREEGHAGPDDNEEVMRALLIHEKKTSSAMAGSVGAAAPVTAANGSDSESETSE
SDDDSPPRPAAVAVHKREEDEEEDDEFEEVADDPIVMVAGRPFSYSEVSQRPELVAQMTP
EEKEAYIAMGQRMFEDLFE
Target Bioclass
Other
Family
TFIIE alpha subunit family
Subcellular location
Nucleus
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Uniprot ID
P29083
Ensemble ID
ENST00000283875.6
HGNC ID
HGNC:4650

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K19(1.20)  LDD0277  [1]
Probe 1
 Probe Info  		Y290(16.56)  LDD3495  [2]
DBIA
 Probe Info  		C129(1.19); C132(1.19)  LDD1093  [3]
5E-2FA
 Probe Info  		N.A.  LDD2235  [4]
m-APA
 Probe Info  		N.A.  LDD2231  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [5]
TFBX
 Probe Info  		N.A.  LDD0148  [6]
Acrolein
 Probe Info  		N.A.  LDD0217  [7]
AOyne
 Probe Info  		12.80  LDD0443  [8]
PAL-AfBPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C026
 Probe Info  		5.43  LDD1732  [9]
C390
 Probe Info  		21.41  LDD2049  [9]
C391
 Probe Info  		12.64  LDD2050  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C129(1.19); C132(1.19)  LDD1093  [3]
 LDCM0215  AC10 PaTu 8988t C129(1.05); C132(1.05)  LDD1094  [3]
 LDCM0226  AC11 PaTu 8988t C129(0.98); C132(0.98)  LDD1105  [3]
 LDCM0230  AC113 PaTu 8988t C129(0.88); C132(0.88)  LDD1109  [3]
 LDCM0231  AC114 PaTu 8988t C129(0.69); C132(0.69)  LDD1110  [3]
 LDCM0232  AC115 PaTu 8988t C129(0.99); C132(0.99)  LDD1111  [3]
 LDCM0233  AC116 PaTu 8988t C129(0.81); C132(0.81)  LDD1112  [3]
 LDCM0234  AC117 PaTu 8988t C129(0.64); C132(0.64)  LDD1113  [3]
 LDCM0235  AC118 PaTu 8988t C129(0.80); C132(0.80)  LDD1114  [3]
 LDCM0236  AC119 PaTu 8988t C129(0.93); C132(0.93)  LDD1115  [3]
 LDCM0237  AC12 PaTu 8988t C129(1.03); C132(1.03)  LDD1116  [3]
 LDCM0238  AC120 PaTu 8988t C129(0.68); C132(0.68)  LDD1117  [3]
 LDCM0239  AC121 PaTu 8988t C129(0.81); C132(0.81)  LDD1118  [3]
 LDCM0240  AC122 PaTu 8988t C129(0.66); C132(0.66)  LDD1119  [3]
 LDCM0241  AC123 PaTu 8988t C129(0.63); C132(0.63)  LDD1120  [3]
 LDCM0242  AC124 PaTu 8988t C129(0.78); C132(0.78)  LDD1121  [3]
 LDCM0243  AC125 PaTu 8988t C129(0.63); C132(0.63)  LDD1122  [3]
 LDCM0244  AC126 PaTu 8988t C129(0.75); C132(0.75)  LDD1123  [3]
 LDCM0245  AC127 PaTu 8988t C129(0.73); C132(0.73)  LDD1124  [3]
 LDCM0259  AC14 PaTu 8988t C129(0.93); C132(0.93)  LDD1138  [3]
 LDCM0270  AC15 PaTu 8988t C129(1.04); C132(1.04)  LDD1149  [3]
 LDCM0276  AC17 PaTu 8988t C129(0.98); C132(0.98)  LDD1155  [3]
 LDCM0277  AC18 PaTu 8988t C129(0.70); C132(0.70)  LDD1156  [3]
 LDCM0278  AC19 PaTu 8988t C129(0.83); C132(0.83)  LDD1157  [3]
 LDCM0279  AC2 PaTu 8988t C129(1.12); C132(1.12)  LDD1158  [3]
 LDCM0280  AC20 PaTu 8988t C129(0.97); C132(0.97)  LDD1159  [3]
 LDCM0281  AC21 PaTu 8988t C129(1.27); C132(1.27)  LDD1160  [3]
 LDCM0282  AC22 PaTu 8988t C129(1.02); C132(1.02)  LDD1161  [3]
 LDCM0283  AC23 PaTu 8988t C129(0.97); C132(0.97)  LDD1162  [3]
 LDCM0284  AC24 PaTu 8988t C129(1.22); C132(1.22)  LDD1163  [3]
 LDCM0285  AC25 PaTu 8988t C129(1.03); C132(1.03)  LDD1164  [3]
 LDCM0286  AC26 PaTu 8988t C129(0.75); C132(0.75)  LDD1165  [3]
 LDCM0287  AC27 PaTu 8988t C129(0.87); C132(0.87)  LDD1166  [3]
 LDCM0288  AC28 PaTu 8988t C129(1.09); C132(1.09)  LDD1167  [3]
 LDCM0289  AC29 PaTu 8988t C129(0.94); C132(0.94)  LDD1168  [3]
 LDCM0290  AC3 PaTu 8988t C129(0.96); C132(0.96)  LDD1169  [3]
 LDCM0291  AC30 PaTu 8988t C129(1.03); C132(1.03)  LDD1170  [3]
 LDCM0292  AC31 PaTu 8988t C129(0.66); C132(0.66)  LDD1171  [3]
 LDCM0293  AC32 PaTu 8988t C129(1.09); C132(1.09)  LDD1172  [3]
 LDCM0294  AC33 PaTu 8988t C129(1.08); C132(1.08)  LDD1173  [3]
 LDCM0295  AC34 PaTu 8988t C129(0.96); C132(0.96)  LDD1174  [3]
 LDCM0296  AC35 PaTu 8988t C129(0.73); C132(0.73)  LDD1175  [3]
 LDCM0297  AC36 PaTu 8988t C129(1.10); C132(1.10)  LDD1176  [3]
 LDCM0298  AC37 PaTu 8988t C129(0.99); C132(0.99)  LDD1177  [3]
 LDCM0299  AC38 PaTu 8988t C129(1.25); C132(1.25)  LDD1178  [3]
 LDCM0300  AC39 PaTu 8988t C129(0.99); C132(0.99)  LDD1179  [3]
 LDCM0301  AC4 PaTu 8988t C129(0.79); C132(0.79)  LDD1180  [3]
 LDCM0302  AC40 PaTu 8988t C129(1.04); C132(1.04)  LDD1181  [3]
 LDCM0303  AC41 PaTu 8988t C129(1.04); C132(1.04)  LDD1182  [3]
 LDCM0304  AC42 PaTu 8988t C129(1.01); C132(1.01)  LDD1183  [3]
 LDCM0305  AC43 PaTu 8988t C129(0.94); C132(0.94)  LDD1184  [3]
 LDCM0306  AC44 PaTu 8988t C129(1.10); C132(1.10)  LDD1185  [3]
 LDCM0307  AC45 PaTu 8988t C129(0.99); C132(0.99)  LDD1186  [3]
 LDCM0312  AC5 PaTu 8988t C129(1.02); C132(1.02)  LDD1191  [3]
 LDCM0315  AC52 HEK-293T C42(1.26)  LDD1554  [10]
 LDCM0320  AC57 PaTu 8988t C129(0.86); C132(0.86)  LDD1199  [3]
 LDCM0321  AC58 PaTu 8988t C129(1.26); C132(1.26)  LDD1200  [3]
 LDCM0322  AC59 PaTu 8988t C129(1.36); C132(1.36)  LDD1201  [3]
 LDCM0323  AC6 PaTu 8988t C129(0.79); C132(0.79)  LDD1202  [3]
 LDCM0324  AC60 PaTu 8988t C129(1.33); C132(1.33)  LDD1203  [3]
 LDCM0325  AC61 PaTu 8988t C129(0.77); C132(0.77)  LDD1204  [3]
 LDCM0326  AC62 PaTu 8988t C129(0.96); C132(0.96)  LDD1205  [3]
 LDCM0327  AC63 PaTu 8988t C129(1.00); C132(1.00)  LDD1206  [3]
 LDCM0328  AC64 PaTu 8988t C129(1.00); C132(1.00)  LDD1207  [3]
 LDCM0329  AC65 PaTu 8988t C129(0.77); C132(0.77)  LDD1208  [3]
 LDCM0330  AC66 PaTu 8988t C129(1.41); C132(1.41)  LDD1209  [3]
 LDCM0331  AC67 PaTu 8988t C129(1.10); C132(1.10)  LDD1210  [3]
 LDCM0334  AC7 PaTu 8988t C129(1.17); C132(1.17)  LDD1213  [3]
 LDCM0345  AC8 PaTu 8988t C129(1.05); C132(1.05)  LDD1224  [3]
 LDCM0248  AKOS034007472 PaTu 8988t C129(1.00); C132(1.00)  LDD1127  [3]
 LDCM0356  AKOS034007680 PaTu 8988t C129(1.00); C132(1.00)  LDD1235  [3]
 LDCM0275  AKOS034007705 PaTu 8988t C129(0.91); C132(0.91)  LDD1154  [3]
 LDCM0369  CL100 PaTu 8988t C129(1.40); C132(1.40)  LDD1248  [3]
 LDCM0370  CL101 PaTu 8988t C129(0.80); C132(0.80)  LDD1249  [3]
 LDCM0371  CL102 PaTu 8988t C129(0.92); C132(0.92)  LDD1250  [3]
 LDCM0372  CL103 PaTu 8988t C129(1.01); C132(1.01)  LDD1251  [3]
 LDCM0373  CL104 PaTu 8988t C129(1.02); C132(1.02)  LDD1252  [3]
 LDCM0374  CL105 PaTu 8988t C129(0.68); C132(0.68)  LDD1253  [3]
 LDCM0375  CL106 PaTu 8988t C129(0.74); C132(0.74)  LDD1254  [3]
 LDCM0376  CL107 PaTu 8988t C129(0.77); C132(0.77)  LDD1255  [3]
 LDCM0377  CL108 PaTu 8988t C129(1.00); C132(1.00)  LDD1256  [3]
 LDCM0378  CL109 PaTu 8988t C129(1.05); C132(1.05)  LDD1257  [3]
 LDCM0380  CL110 PaTu 8988t C129(0.78); C132(0.78)  LDD1259  [3]
 LDCM0381  CL111 PaTu 8988t C129(1.02); C132(1.02)  LDD1260  [3]
 LDCM0382  CL112 PaTu 8988t C129(1.05); C132(1.05)  LDD1261  [3]
 LDCM0383  CL113 PaTu 8988t C129(0.90); C132(0.90)  LDD1262  [3]
 LDCM0384  CL114 PaTu 8988t C129(0.74); C132(0.74)  LDD1263  [3]
 LDCM0385  CL115 PaTu 8988t C129(0.76); C132(0.76)  LDD1264  [3]
 LDCM0386  CL116 PaTu 8988t C129(1.03); C132(1.03)  LDD1265  [3]
 LDCM0387  CL117 PaTu 8988t C129(1.05); C132(1.05)  LDD1266  [3]
 LDCM0388  CL118 PaTu 8988t C129(2.46); C132(2.46)  LDD1267  [3]
 LDCM0389  CL119 PaTu 8988t C129(0.88); C132(0.88)  LDD1268  [3]
 LDCM0391  CL120 PaTu 8988t C129(0.86); C132(0.86)  LDD1270  [3]
 LDCM0396  CL125 PaTu 8988t C129(0.81); C132(0.81)  LDD1275  [3]
 LDCM0397  CL126 PaTu 8988t C129(0.81); C132(0.81)  LDD1276  [3]
 LDCM0398  CL127 PaTu 8988t C129(0.92); C132(0.92)  LDD1277  [3]
 LDCM0399  CL128 PaTu 8988t C129(1.14); C132(1.14)  LDD1278  [3]
 LDCM0408  CL20 HEK-293T C42(0.49)  LDD1612  [10]
 LDCM0420  CL31 PaTu 8988t C129(1.00); C132(1.00)  LDD1299  [3]
 LDCM0421  CL32 PaTu 8988t C129(0.98); C132(0.98)  LDD1300  [3]
 LDCM0422  CL33 PaTu 8988t C129(0.94); C132(0.94)  LDD1301  [3]
 LDCM0423  CL34 PaTu 8988t C129(1.27); C132(1.27)  LDD1302  [3]
 LDCM0424  CL35 PaTu 8988t C129(1.32); C132(1.32)  LDD1303  [3]
 LDCM0425  CL36 PaTu 8988t C129(0.94); C132(0.94)  LDD1304  [3]
 LDCM0426  CL37 PaTu 8988t C129(1.40); C132(1.40)  LDD1305  [3]
 LDCM0428  CL39 PaTu 8988t C129(1.41); C132(1.41)  LDD1307  [3]
 LDCM0430  CL40 PaTu 8988t C129(1.36); C132(1.36)  LDD1309  [3]
 LDCM0431  CL41 PaTu 8988t C129(1.61); C132(1.61)  LDD1310  [3]
 LDCM0432  CL42 PaTu 8988t C129(1.69); C132(1.69)  LDD1311  [3]
 LDCM0433  CL43 PaTu 8988t C129(2.16); C132(2.16)  LDD1312  [3]
 LDCM0434  CL44 PaTu 8988t C129(1.08); C132(1.08)  LDD1313  [3]
 LDCM0435  CL45 PaTu 8988t C129(1.08); C132(1.08)  LDD1314  [3]
 LDCM0447  CL56 HEK-293T C42(0.61)  LDD1650  [10]
 LDCM0453  CL61 PaTu 8988t C129(1.23); C132(1.23)  LDD1332  [3]
 LDCM0454  CL62 PaTu 8988t C129(0.95); C132(0.95)  LDD1333  [3]
 LDCM0455  CL63 PaTu 8988t C129(1.55); C132(1.55)  LDD1334  [3]
 LDCM0456  CL64 PaTu 8988t C129(1.20); C132(1.20)  LDD1335  [3]
 LDCM0457  CL65 PaTu 8988t C129(0.92); C132(0.92)  LDD1336  [3]
 LDCM0458  CL66 PaTu 8988t C129(1.45); C132(1.45)  LDD1337  [3]
 LDCM0459  CL67 PaTu 8988t C129(1.77); C132(1.77)  LDD1338  [3]
 LDCM0460  CL68 PaTu 8988t C129(2.15); C132(2.15)  LDD1339  [3]
 LDCM0461  CL69 PaTu 8988t C129(1.39); C132(1.39)  LDD1340  [3]
 LDCM0463  CL70 PaTu 8988t C129(1.52); C132(1.52)  LDD1342  [3]
 LDCM0464  CL71 PaTu 8988t C129(0.82); C132(0.82)  LDD1343  [3]
 LDCM0465  CL72 PaTu 8988t C129(0.69); C132(0.69)  LDD1344  [3]
 LDCM0466  CL73 PaTu 8988t C129(1.30); C132(1.30)  LDD1345  [3]
 LDCM0467  CL74 PaTu 8988t C129(1.21); C132(1.21)  LDD1346  [3]
 LDCM0469  CL76 PaTu 8988t C129(0.86); C132(0.86)  LDD1348  [3]
 LDCM0470  CL77 PaTu 8988t C129(0.86); C132(0.86)  LDD1349  [3]
 LDCM0471  CL78 PaTu 8988t C129(1.31); C132(1.31)  LDD1350  [3]
 LDCM0472  CL79 PaTu 8988t C129(1.12); C132(1.12)  LDD1351  [3]
 LDCM0473  CL8 HEK-293T C42(0.57)  LDD1676  [10]
 LDCM0474  CL80 PaTu 8988t C129(1.20); C132(1.20)  LDD1353  [3]
 LDCM0475  CL81 PaTu 8988t C129(0.95); C132(0.95)  LDD1354  [3]
 LDCM0476  CL82 PaTu 8988t C129(1.35); C132(1.35)  LDD1355  [3]
 LDCM0477  CL83 PaTu 8988t C129(1.07); C132(1.07)  LDD1356  [3]
 LDCM0478  CL84 PaTu 8988t C129(1.13); C132(1.13)  LDD1357  [3]
 LDCM0479  CL85 PaTu 8988t C129(0.83); C132(0.83)  LDD1358  [3]
 LDCM0480  CL86 PaTu 8988t C129(0.97); C132(0.97)  LDD1359  [3]
 LDCM0481  CL87 PaTu 8988t C129(1.38); C132(1.38)  LDD1360  [3]
 LDCM0482  CL88 PaTu 8988t C129(1.16); C132(1.16)  LDD1361  [3]
 LDCM0483  CL89 PaTu 8988t C129(0.92); C132(0.92)  LDD1362  [3]
 LDCM0485  CL90 PaTu 8988t C129(0.95); C132(0.95)  LDD1364  [3]
 LDCM0486  CL91 PaTu 8988t C129(0.78); C132(0.78)  LDD1365  [3]
 LDCM0487  CL92 PaTu 8988t C129(0.88); C132(0.88)  LDD1366  [3]
 LDCM0488  CL93 PaTu 8988t C129(1.06); C132(1.06)  LDD1367  [3]
 LDCM0489  CL94 PaTu 8988t C129(1.13); C132(1.13)  LDD1368  [3]
 LDCM0490  CL95 PaTu 8988t C129(0.99); C132(0.99)  LDD1369  [3]
 LDCM0491  CL96 PaTu 8988t C129(0.93); C132(0.93)  LDD1370  [3]
 LDCM0492  CL97 PaTu 8988t C129(1.04); C132(1.04)  LDD1371  [3]
 LDCM0493  CL98 PaTu 8988t C129(0.97); C132(0.97)  LDD1372  [3]
 LDCM0494  CL99 PaTu 8988t C129(1.00); C132(1.00)  LDD1373  [3]
 LDCM0625  F8 Ramos C42(0.73)  LDD2187  [11]
 LDCM0572  Fragment10 Ramos C42(0.54)  LDD2189  [11]
 LDCM0573  Fragment11 Ramos C42(7.54)  LDD2190  [11]
 LDCM0574  Fragment12 Ramos C42(0.65)  LDD2191  [11]
 LDCM0575  Fragment13 Ramos C42(0.69)  LDD2192  [11]
 LDCM0576  Fragment14 Ramos C42(0.77)  LDD2193  [11]
 LDCM0579  Fragment20 Ramos C42(0.69)  LDD2194  [11]
 LDCM0580  Fragment21 Ramos C42(0.80)  LDD2195  [11]
 LDCM0582  Fragment23 Ramos C42(0.71)  LDD2196  [11]
 LDCM0578  Fragment27 Ramos C42(0.76)  LDD2197  [11]
 LDCM0586  Fragment28 Ramos C42(0.62)  LDD2198  [11]
 LDCM0588  Fragment30 Ramos C42(0.46)  LDD2199  [11]
 LDCM0589  Fragment31 Ramos C42(0.64)  LDD2200  [11]
 LDCM0590  Fragment32 Ramos C42(0.55)  LDD2201  [11]
 LDCM0468  Fragment33 PaTu 8988t C129(1.26); C132(1.26)  LDD1347  [3]
 LDCM0596  Fragment38 Ramos C42(0.54)  LDD2203  [11]
 LDCM0566  Fragment4 Ramos C42(0.66)  LDD2184  [11]
 LDCM0427  Fragment51 PaTu 8988t C129(1.47); C132(1.47)  LDD1306  [3]
 LDCM0610  Fragment52 Ramos C42(0.52)  LDD2204  [11]
 LDCM0614  Fragment56 Ramos C42(0.55)  LDD2205  [11]
 LDCM0569  Fragment7 Ramos C42(0.85)  LDD2186  [11]
 LDCM0571  Fragment9 Ramos C42(0.41)  LDD2188  [11]
 LDCM0022  KB02 Ramos C42(0.57)  LDD2182  [11]
 LDCM0023  KB03 Ramos C42(0.73)  LDD2183  [11]
 LDCM0024  KB05 Ramos C42(0.35)  LDD2185  [11]
 LDCM0109  NEM HeLa N.A.  LDD0225  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Notch-regulated ankyrin repeat-containing protein (NRARP) NRARP family Q7Z6K4
General transcription factor IIH subunit 1 (GTF2H1) TFB1 family P32780
Transcription initiation factor IIE subunit beta (GTF2E2) TFIIE beta subunit family P29084
TBC1 domain family member 21 (TBC1D21) . Q8IYX1

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
8 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
9 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578