Details of the Target

General Information of Target

Target ID LDTP18467
Target Name LYR motif-containing protein 2 (LYRM2)
Gene Name LYRM2
Gene ID 57226
Synonyms
LYR motif-containing protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDPALAAQMSEAVAEKMLQYRRDTAGWKICREGNGVSVSWRPSVEFPGNLYRGEGIVYGT
LEEVWDCVKPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLV
LVKRYEDGTISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDL
SGYLPQNVVDSFFPRSMTRFYANLQKAVKQFHE
Target Bioclass
Other
Family
Complex I LYR family
Subcellular location
Mitochondrion
Function Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.
Uniprot ID
Q9NU23
Ensemble ID
ENST00000523377.2
HGNC ID
HGNC:25229

Probe(s) Labeling This Target

PAL-AfBPP Probe
Click To Hide/Show 21 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C056
 Probe Info  		54.19  LDD1753  [1]
C163
 Probe Info  		6.19  LDD1843  [1]
C165
 Probe Info  		30.27  LDD1845  [1]
C177
 Probe Info  		9.00  LDD1856  [1]
C178
 Probe Info  		14.62  LDD1857  [1]
C210
 Probe Info  		48.17  LDD1884  [1]
C218
 Probe Info  		34.54  LDD1892  [1]
C220
 Probe Info  		36.00  LDD1894  [1]
C228
 Probe Info  		54.57  LDD1901  [1]
C313
 Probe Info  		28.84  LDD1980  [1]
C314
 Probe Info  		14.22  LDD1981  [1]
C362
 Probe Info  		99.73  LDD2023  [1]
C363
 Probe Info  		39.12  LDD2024  [1]
C364
 Probe Info  		33.82  LDD2025  [1]
C366
 Probe Info  		8.34  LDD2027  [1]
C367
 Probe Info  		6.32  LDD2028  [1]
C373
 Probe Info  		7.62  LDD2033  [1]
C383
 Probe Info  		34.06  LDD2042  [1]
C386
 Probe Info  		8.22  LDD2045  [1]
C388
 Probe Info  		41.07  LDD2047  [1]
C390
 Probe Info  		23.92  LDD2049  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein FAM9B (FAM9B) FAM9 family Q8IZU0

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587