Details of the Probe

General Information of Probe

Probe ID
LDPC0444
Probe Name
C210
Synonyms
Z3433407249
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 346.4
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H18N6O
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-3-(1H-indol-3-yl)-1H-pyrazole-5-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2=CC(=NN2)C3=CNC4=CC=CC=C43
InChI
InChI=1S/C19H18N6O/c1-2-3-8-19(24-25-19)9-10-20-18(26)17-11-16(22-23-17)14-12-21-15-7-5-4-6-13(14)15/h1,4-7,11-12,21H,3,8-10H2,(H,20,26)(H,22,23)
InChIKey
IUIBTTVXFZIYGI-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

108 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 8 (PSMD8) LDTP04196 62.25  LDD1884 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 72.00  LDD1884 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 63.56  LDD1884 
Acyl-CoA dehydrogenase family member 11 (ACAD11) LDTP07873 41.93  LDD1884 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 61.82  LDD1884 
Adenosine deaminase (ADA) LDTP01803 99.73  LDD1884 
ADP-dependent glucokinase (ADPGK) LDTP11127 77.71  LDD1884 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 51.63  LDD1884 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 75.58  LDD1884 
Antigen peptide transporter 1 (TAP1) LDTP05408 46.21  LDD1884 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 39.95  LDD1884 
Atlastin-2 (ATL2) LDTP09251 44.32  LDD1884 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 38.85  LDD1884 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 47.84  LDD1884 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 58.89  LDD1884 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 43.11  LDD1884 
Catechol O-methyltransferase (COMT) LDTP03145 68.12  LDD1884 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 75.06  LDD1884 
Ceramide synthase 1 (CERS1) LDTP03394 44.02  LDD1884 
Ceramide synthase 2 (CERS2) LDTP10329 83.29  LDD1884 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 48.84  LDD1884 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 49.18  LDD1884 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 56.49  LDD1884 
Cullin-1 (CUL1) LDTP05946 43.41  LDD1884 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 51.98  LDD1884 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD1884 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 99.73  LDD1884 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1884 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 82.14  LDD1884 
DCN1-like protein 4 (DCUN1D4) LDTP09799 48.84  LDD1884 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 52.35  LDD1884 
Dehydrogenase/reductase SDR family member 13 (DHRS13) LDTP15154 39.12  LDD1884 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 47.50  LDD1884 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 45.57  LDD1884 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 83.87  LDD1884 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 41.36  LDD1884 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 68.59  LDD1884 
E3 ubiquitin-protein ligase NEDD4 (NEDD4) LDTP04114 66.72  LDD1884 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 59.71  LDD1884 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 41.07  LDD1884 
Endonuclease III-like protein 1 (NTHL1) LDTP05143 65.34  LDD1884 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 69.07  LDD1884 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 39.40  LDD1884 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 55.33  LDD1884 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 39.95  LDD1884 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 68.12  LDD1884 
Heme oxygenase 1 (HMOX1) LDTP02359 54.57  LDD1884 
Heme oxygenase 2 (HMOX2) LDTP03540 69.55  LDD1884 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 60.13  LDD1884 
Holocytochrome c-type synthase (HCCS) LDTP04581 46.85  LDD1884 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 84.45  LDD1884 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 44.94  LDD1884 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 81.57  LDD1884 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 52.35  LDD1884 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 52.35  LDD1884 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 40.22  LDD1884 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 99.04  LDD1884 
Methionine aminopeptidase 1 (METAP1) LDTP04565 55.33  LDD1884 
Mitofusin-1 (MFN1) LDTP08530 44.32  LDD1884 
Myotubularin-related protein 12 (MTMR12) LDTP11617 74.03  LDD1884 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 53.45  LDD1884 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 99.73  LDD1884 
NADH dehydrogenase 1 alpha subcomplex subunit 7 (NDUFA7) LDTP01518 58.89  LDD1884 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 99.73  LDD1884 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 38.85  LDD1884 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 99.73  LDD1884 
NADH dehydrogenase iron-sulfur protein 8, mitochondrial (NDUFS8) LDTP00218 63.56  LDD1884 
Outer mitochondrial transmembrane helix translocase (ATAD1) LDTP09070 46.53  LDD1884 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 41.93  LDD1884 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 56.49  LDD1884 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 48.84  LDD1884 
Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) LDTP11209 40.22  LDD1884 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 64.00  LDD1884 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 79.34  LDD1884 
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1) LDTP09390 39.40  LDD1884 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 70.03  LDD1884 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 89.88  LDD1884 
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) LDTP00645 44.94  LDD1884 
Prostaglandin reductase 3 (PTGR3) LDTP15422 99.73  LDD1884 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 46.53  LDD1884 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 42.22  LDD1884 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 62.68  LDD1884 
Protoporphyrinogen oxidase (PPOX) LDTP04353 45.57  LDD1884 
Ras-related protein Rab-11B (RAB11B) LDTP06501 48.17  LDD1884 
Ras-related protein Rab-24 (RAB24) LDTP10020 65.34  LDD1884 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 61.82  LDD1884 
Retinol dehydrogenase 13 (RDH13) LDTP09061 48.17  LDD1884 
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) LDTP00890 49.18  LDD1884 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 45.25  LDD1884 
Selenocysteine-specific elongation factor (EEFSEC) LDTP14723 56.49  LDD1884 
Serine/threonine-protein kinase PAK 1 (PAK1) LDTP05769 44.63  LDD1884 
Serine/threonine-protein kinase ULK3 (ULK3) LDTP07577 44.02  LDD1884 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 99.73  LDD1884 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 95.01  LDD1884 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 72.00  LDD1884 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 56.10  LDD1884 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 64.89  LDD1884 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 57.68  LDD1884 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 56.49  LDD1884 
Sulfhydryl oxidase 2 (QSOX2) LDTP07813 44.32  LDD1884 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 48.17  LDD1884 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 46.21  LDD1884 
Torsin-1B (TOR1B) LDTP00400 59.30  LDD1884 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 44.63  LDD1884 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 51.98  LDD1884 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 42.81  LDD1884 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 41.64  LDD1884 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 45.57  LDD1884 
------------------------------------------------------------------------------------
⏷ Show the Full List of 108 Enzyme
83 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 41.93  LDD1884 
Anoctamin-10 (ANO10) LDTP12704 39.40  LDD1884 
ATP synthase subunit a (MT-ATP6) LDTP01804 77.17  LDD1884 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 49.87  LDD1884 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 49.87  LDD1884 
BOS complex subunit NCLN (NCLN) LDTP10036 76.11  LDD1884 
BRI3-binding protein (BRI3BP) LDTP15648 68.59  LDD1884 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 43.11  LDD1884 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 58.89  LDD1884 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 60.13  LDD1884 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD1884 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 56.49  LDD1884 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 39.12  LDD1884 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 99.73  LDD1884 
Exportin-4 (XPO4) LDTP11607 53.45  LDD1884 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 94.35  LDD1884 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 42.81  LDD1884 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 72.00  LDD1884 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 99.73  LDD1884 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 54.95  LDD1884 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 78.79  LDD1884 
Metaxin-1 (MTX1) LDTP05900 99.73  LDD1884 
Metaxin-2 (MTX2) LDTP01217 63.56  LDD1884 
MICOS complex subunit MIC26 (APOO) LDTP11250 55.33  LDD1884 
MICOS complex subunit MIC60 (IMMT) LDTP06660 48.84  LDD1884 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 78.25  LDD1884 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 44.63  LDD1884 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 62.68  LDD1884 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 57.28  LDD1884 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 43.11  LDD1884 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 58.49  LDD1884 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 46.85  LDD1884 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 95.01  LDD1884 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1884 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 99.73  LDD1884 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 74.03  LDD1884 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 41.07  LDD1884 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 51.98  LDD1884 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 41.93  LDD1884 
Mitochondrial potassium channel ATP-binding subunit (ABCB8) LDTP12644 47.50  LDD1884 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 55.33  LDD1884 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 99.73  LDD1884 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 41.64  LDD1884 
Nucleoporin NUP35 (NUP35) LDTP09204 41.07  LDD1884 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 53.45  LDD1884 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 57.68  LDD1884 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 42.22  LDD1884 
Prosaposin (PSAP) LDTP02215 56.49  LDD1884 
Protein FAM8A1 (FAM8A1) LDTP16190 99.73  LDD1884 
Protein GPR107 (GPR107) LDTP07236 64.45  LDD1884 
Protein OS-9 (OS9) LDTP05871 39.95  LDD1884 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 58.49  LDD1884 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 62.25  LDD1884 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 84.45  LDD1884 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 85.63  LDD1884 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 39.12  LDD1884 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 99.73  LDD1884 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 99.73  LDD1884 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 99.73  LDD1884 
Sugar transporter SWEET1 (SLC50A1) LDTP11136 42.81  LDD1884 
SUN domain-containing protein 2 (SUN2) LDTP13256 71.51  LDD1884 
Surfeit locus protein 4 (SURF4) LDTP00592 88.65  LDD1884 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 99.73  LDD1884 
Syntaxin-5 (STX5) LDTP05780 48.84  LDD1884 
Syntenin-1 (SDCBP) LDTP00310 47.84  LDD1884 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 45.57  LDD1884 
Translocator protein (TSPO) LDTP03546 76.11  LDD1884 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1884 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 73.01  LDD1884 
Transmembrane protein 126A (TMEM126A) LDTP15948 99.73  LDD1884 
Transmembrane protein 14C (TMEM14C) LDTP12979 53.08  LDD1884 
Transmembrane protein 160 (TMEM160) LDTP20002 99.73  LDD1884 
Transmembrane protein 199 (TMEM199) LDTP08881 70.03  LDD1884 
Transmembrane protein 230 (TMEM230) LDTP10065 54.57  LDD1884 
Transmembrane protein 245 (TMEM245) LDTP15979 64.89  LDD1884 
Transmembrane protein 59 (TMEM59) LDTP11406 48.17  LDD1884 
Transmembrane protein 87A (TMEM87A) LDTP15481 57.68  LDD1884 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 46.85  LDD1884 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 62.68  LDD1884 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 95.67  LDD1884 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 72.50  LDD1884 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 67.18  LDD1884 
Wolframin (WFS1) LDTP01380 48.84  LDD1884 
------------------------------------------------------------------------------------
⏷ Show the Full List of 83 Transporter and channel
5 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 38.85  LDD1884 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 39.40  LDD1884 
Paraspeckle component 1 (PSPC1) LDTP09694 39.40  LDD1884 
Splicing factor, proline- and glutamine-rich (SFPQ) LDTP03212 43.11  LDD1884 
Y-box-binding protein 1 (YBX1) LDTP05065 49.87  LDD1884 
------------------------------------------------------------------------------------
112 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Actin-related protein 3 (ACTR3) LDTP04902 42.22  LDD1884 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 45.57  LDD1884 
Alpha-internexin (INA) LDTP06527 49.87  LDD1884 
Apolipoprotein L2 (APOL2) LDTP11076 92.41  LDD1884 
Ataxin-10 (ATXN10) LDTP13091 41.64  LDD1884 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 59.71  LDD1884 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 68.12  LDD1884 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 49.87  LDD1884 
Calmodulin-3 (CALM3) LDTP02443 85.04  LDD1884 
Calumenin (CALU) LDTP00887 60.13  LDD1884 
Centrin-2 (CETN2) LDTP03926 50.91  LDD1884 
Centrosomal protein of 290 kDa (CEP290) LDTP00531 48.84  LDD1884 
Coatomer subunit delta (ARCN1) LDTP04181 42.81  LDD1884 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 88.65  LDD1884 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 73.01  LDD1884 
DENN domain-containing protein 11 (DENND11) LDTP16577 44.63  LDD1884 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 61.82  LDD1884 
DnaJ homolog subfamily B member 11 (DNAJB11) LDTP13152 40.50  LDD1884 
DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 39.12  LDD1884 
Dynactin subunit 3 (DCTN3) LDTP01359 66.26  LDD1884 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 67.65  LDD1884 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 45.57  LDD1884 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 90.51  LDD1884 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 71.51  LDD1884 
Erbin (ERBIN) LDTP10782 43.71  LDD1884 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 53.08  LDD1884 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 52.71  LDD1884 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 44.94  LDD1884 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 50.56  LDD1884 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 51.63  LDD1884 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 39.40  LDD1884 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 41.36  LDD1884 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 56.89  LDD1884 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 64.00  LDD1884 
Iron-sulfur cluster transfer protein NUBPL (NUBPL) LDTP09325 41.07  LDD1884 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 99.73  LDD1884 
Kinesin light chain 4 (KLC4) LDTP12591 40.79  LDD1884 
Lamin-B2 (LMNB2) LDTP05400 44.94  LDD1884 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 59.71  LDD1884 
Large ribosomal subunit protein mL65 (MRPS30) LDTP16055 57.28  LDD1884 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 72.00  LDD1884 
Leucine-rich repeat-containing protein 1 (LRRC1) LDTP15885 44.94  LDD1884 
LYR motif-containing protein 2 (LYRM2) LDTP18467 48.17  LDD1884 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 53.82  LDD1884 
Membralin (TMEM259) LDTP14939 63.56  LDD1884 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 91.77  LDD1884 
MICOS complex subunit MIC27 (APOOL) LDTP07718 45.89  LDD1884 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 55.33  LDD1884 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1884 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1884 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 41.07  LDD1884 
NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2) LDTP08761 51.27  LDD1884 
Negative elongation factor C/D (NELFCD) LDTP08594 62.68  LDD1884 
Nestin (NES) LDTP04206 38.85  LDD1884 
Neurofilament light polypeptide (NEFL) LDTP02180 59.30  LDD1884 
Neurofilament medium polypeptide (NEFM) LDTP02181 67.65  LDD1884 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 47.50  LDD1884 
Nucleobindin-2 (NUCB2) LDTP05160 59.30  LDD1884 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 40.50  LDD1884 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 55.33  LDD1884 
Optic atrophy 3 protein (OPA3) LDTP16006 55.72  LDD1884 
Phosducin-like protein 3 (PDCL3) LDTP11825 42.81  LDD1884 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 49.52  LDD1884 
Prelamin-A/C (LMNA) LDTP01932 84.45  LDD1884 
Programmed cell death protein 5 (PDCD5) LDTP00417 39.12  LDD1884 
Prohibitin-2 (PHB2) LDTP10924 58.49  LDD1884 
Protein angel homolog 1 (ANGEL1) LDTP16249 44.32  LDD1884 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 48.84  LDD1884 
Protein CEBPZOS (CEBPZOS) LDTP18883 99.73  LDD1884 
Protein FAM162A (FAM162A) LDTP10056 99.73  LDD1884 
Protein jagunal homolog 1 (JAGN1) LDTP08904 40.50  LDD1884 
Protein kish-B (TMEM167B) LDTP12545 50.56  LDD1884 
Protein NipSnap homolog 1 (NIPSNAP1) LDTP19912 43.41  LDD1884 
Protein SET (SET) LDTP05277 80.45  LDD1884 
Protein SYS1 homolog (SYS1) LDTP08796 55.33  LDD1884 
Protein UXT (UXT) LDTP13125 59.30  LDD1884 
Protein YIF1A (YIF1A) LDTP01494 89.26  LDD1884 
RalBP1-associated Eps domain-containing protein 1 (REPS1) LDTP10203 40.22  LDD1884 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 54.19  LDD1884 
Reticulocalbin-2 (RCN2) LDTP06097 41.64  LDD1884 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD1884 
Reticulon-4 (RTN4) LDTP12412 99.73  LDD1884 
RNA polymerase II-associated protein 1 (RPAP1) LDTP11327 43.11  LDD1884 
RNA-binding protein 3 (RBM3) LDTP05226 54.57  LDD1884 
Sec1 family domain-containing protein 2 (SCFD2) LDTP18079 41.93  LDD1884 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 53.82  LDD1884 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 61.39  LDD1884 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 48.50  LDD1884 
Small integral membrane protein 12 (SMIM12) LDTP19859 53.82  LDD1884 
Survival motor neuron protein (SMN1; SMN2) LDTP06587 38.85  LDD1884 
Synaptogyrin-2 (SYNGR2) LDTP00859 58.89  LDD1884 
Syntaxin-10 (STX10) LDTP00986 63.56  LDD1884 
Syntaxin-18 (STX18) LDTP13086 87.43  LDD1884 
Tetraspanin-6 (TSPAN6) LDTP14458 48.17  LDD1884 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 55.72  LDD1884 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 99.73  LDD1884 
TraB domain-containing protein (TRABD) LDTP19963 71.51  LDD1884 
Transformer-2 protein homolog alpha (TRA2A) LDTP05937 40.50  LDD1884 
Translocon-associated protein subunit delta (SSR4) LDTP04425 49.18  LDD1884 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 41.07  LDD1884 
Trophoblast glycoprotein (TPBG) LDTP05960 49.18  LDD1884 
Tropomyosin alpha-1 chain (TPM1) LDTP02351 46.85  LDD1884 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 38.85  LDD1884 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 58.89  LDD1884 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 62.68  LDD1884 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 60.97  LDD1884 
Ubiquitin-associated protein 2 (UBAP2) LDTP07132 40.50  LDD1884 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 50.21  LDD1884 
UPF0449 protein C19orf25 (C19orf25) LDTP13214 43.41  LDD1884 
UPF0489 protein C5orf22 (C5orf22) LDTP17129 42.81  LDD1884 
Vimentin (VIM) LDTP02297 99.73  LDD1884 
WD repeat and coiled-coil-containing protein (WDCP) LDTP11995 44.02  LDD1884 
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⏷ Show the Full List of 112 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1884 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587