Details of the Target

General Information of Target

Target ID LDTP16055
Target Name Large ribosomal subunit protein mL65 (MRPS30)
Gene Name MRPS30
Gene ID 10884
Synonyms
PDCD9; Large ribosomal subunit protein mL65; 39S ribosomal protein S30, mitochondrial; MRP-S30; S30mt; Large ribosomal subunit protein mS30; Programmed cell death protein 9
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPDELTEPGRATPARASSFLIENLLAAEAKGAGRATQGDGSREDEEEDDDDPEDEDAEQA
RRRRLQRRRQLLAGTGPGGEARARALLGPGALGLGPRPPPGPGPPFALGCGGAARWYPRA
HGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGPGPGAVQREAAELAARGPAAGTEEAS
ELAEVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASL
QLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQRLVRVPVLYHESPPAAAAAGPPA
TLPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPGLV
Target Bioclass
Other
Family
Mitochondrion-specific ribosomal protein mL65 family
Subcellular location
Mitochondrion
Uniprot ID
Q9NP92
Ensemble ID
ENST00000507110.6
HGNC ID
HGNC:8769

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 17 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
N1
 Probe Info  		100.00  LDD0242  [2]
AHL-Pu-1
 Probe Info  		C147(2.79)  LDD0170  [3]
DBIA
 Probe Info  		C204(0.93)  LDD0078  [4]
CY-1
 Probe Info  		Q232(0.00); Q240(0.00)  LDD0246  [2]
4-Iodoacetamidophenylacetylene
 Probe Info  		C204(0.00); C316(0.00)  LDD0038  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [6]
Lodoacetamide azide
 Probe Info  		C204(0.00); C393(0.00); C266(0.00)  LDD0037  [5]
IPM
 Probe Info  		N.A.  LDD0025  [7]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [7]
NAIA_4
 Probe Info  		N.A.  LDD2226  [8]
TFBX
 Probe Info  		N.A.  LDD0027  [7]
1c-yne
 Probe Info  		N.A.  LDD0228  [9]
Acrolein
 Probe Info  		N.A.  LDD0217  [10]
Methacrolein
 Probe Info  		N.A.  LDD0218  [10]
AOyne
 Probe Info  		9.70  LDD0443  [11]
HHS-465
 Probe Info  		N.A.  LDD2240  [12]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C210
 Probe Info  		57.28  LDD1884  [13]
VE-P
 Probe Info  		N.A.  LDD0396  [14]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C147(2.79)  LDD0170  [3]
 LDCM0214  AC1 HCT 116 C147(0.80); C149(0.80); C204(0.75); C292(0.67)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C147(0.57); C149(0.57); C204(0.67); C292(0.46)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C147(0.34); C149(0.34); C204(0.58); C292(0.61)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C147(0.61); C149(0.61); C204(0.73); C292(0.64)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C147(0.46); C149(0.46); C204(0.67); C292(0.62)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C147(0.13); C149(0.13); C204(0.74); C292(0.48)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C147(0.18); C149(0.18); C204(0.69); C292(0.58)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C147(0.17); C149(0.17); C204(0.65); C292(0.51)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C147(0.16); C149(0.16); C204(0.64); C292(0.53)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C147(0.13); C149(0.13); C204(0.70); C292(0.53)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C147(0.69); C149(0.69); C204(0.68); C292(0.68)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C147(1.04); C149(1.04); C204(0.66); C292(1.10)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C147(0.44); C149(0.44); C204(0.70); C292(0.40)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C147(0.54); C149(0.54); C204(0.65); C292(0.73)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C147(0.90); C149(0.90); C204(0.74); C292(0.71)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C147(0.25); C149(0.25); C204(0.69); C292(0.46)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C204(1.02); C292(0.83); C293(0.83); C393(1.06)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C204(0.79); C292(0.58); C293(0.58); C393(0.80)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C204(0.73); C292(0.44); C293(0.44); C393(1.01)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C204(0.78); C292(0.44); C293(0.44); C393(0.98)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C204(0.80); C292(0.57); C293(0.57); C393(0.86)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C204(0.72); C292(0.69); C293(0.69); C393(0.90)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C204(0.75); C292(0.55); C293(0.55); C393(0.89)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C147(1.19); C149(1.19); C204(0.71); C292(0.67)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C204(0.83); C292(0.76); C293(0.76); C393(0.93)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C204(0.82); C292(1.00); C293(1.00); C393(1.52)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C204(0.79); C292(0.81); C293(0.81); C393(0.84)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C204(1.01); C292(1.06); C293(1.06); C393(0.86)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C204(0.89); C292(0.84); C293(0.84); C393(1.18)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C204(0.95); C292(0.77); C293(0.77); C393(0.93)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C204(0.89); C292(0.61); C293(0.61); C393(0.96)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C204(0.86); C292(0.56); C293(0.56); C393(1.08)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C147(0.51); C149(0.51); C204(1.11); C292(0.76)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C147(1.76); C149(1.76); C204(1.12); C292(1.87)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C147(0.75); C149(0.75); C204(1.10); C292(0.71)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C147(1.50); C149(1.50); C204(1.75); C292(1.95)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C147(1.96); C149(1.96); C204(0.95); C292(1.78)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C147(0.84); C149(0.84); C204(0.94); C292(0.83)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C147(0.60); C149(0.60); C204(1.22); C292(0.73)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C147(0.69); C149(0.69); C204(1.03); C292(0.71)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C147(0.76); C149(0.76); C204(0.98); C292(0.77)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C147(1.24); C149(1.24); C204(0.90); C292(1.10)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C147(0.61); C149(0.61); C204(0.86); C292(0.78)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C147(0.84); C149(0.84); C204(0.94); C292(0.86)  LDD0575  [4]
 LDCM0259  AC14 HCT 116 C147(0.52); C149(0.52); C204(0.77); C292(0.59)  LDD0576  [4]
 LDCM0260  AC140 HCT 116 C147(0.64); C149(0.64); C204(0.85); C292(0.61)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C147(0.73); C149(0.73); C204(0.77); C292(0.76)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C147(2.99); C149(2.99); C204(1.02); C292(2.21)  LDD0579  [4]
 LDCM0263  AC143 HCT 116 C204(0.81); C147(0.87); C149(0.87); C292(0.89)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C292(0.20); C293(0.20); C147(0.25); C149(0.25)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C147(0.60); C149(0.60); C292(0.61); C293(0.61)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C292(0.38); C293(0.38); C147(0.47); C149(0.47)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C292(0.16); C293(0.16); C147(0.19); C149(0.19)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C292(0.14); C293(0.14); C147(0.19); C149(0.19)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C292(0.16); C293(0.16); C147(0.21); C149(0.21)  LDD0586  [4]
 LDCM0270  AC15 HCT 116 C147(0.37); C149(0.37); C292(0.40); C293(0.40)  LDD0587  [4]
 LDCM0271  AC150 HCT 116 C204(0.76); C292(0.76); C293(0.76); C147(0.84)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C204(0.70); C292(1.01); C293(1.01); C147(1.22)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C292(0.17); C293(0.17); C147(0.21); C149(0.21)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C292(0.16); C293(0.16); C147(0.19); C149(0.19)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C147(0.31); C149(0.31); C204(0.71); C292(0.27)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C147(0.30); C149(0.30); C204(0.68); C292(0.25)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C147(0.97); C149(0.97); C204(1.04); C292(0.93)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C147(1.12); C149(1.12); C204(1.77); C292(1.34)  LDD2161  [4]
 LDCM0276  AC17 HCT 116 C204(0.74); C292(0.81); C293(0.81); C147(0.85)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C292(0.22); C293(0.22); C147(0.40); C149(0.40)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C292(0.54); C293(0.54); C393(0.72); C147(0.72)  LDD0595  [4]
 LDCM0279  AC2 HCT 116 C292(0.59); C293(0.59); C204(0.64); C147(0.91)  LDD0596  [4]
 LDCM0280  AC20 HCT 116 C393(0.62); C292(0.78); C293(0.78); C147(0.83)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C292(0.64); C293(0.64); C393(0.68); C147(0.70)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C393(0.76); C204(0.86); C292(1.07); C293(1.07)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C393(0.44); C292(0.66); C293(0.66); C204(0.72)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C393(0.51); C204(0.85); C292(0.89); C293(0.89)  LDD0601  [4]
 LDCM0285  AC25 HCT 116 C292(0.57); C293(0.57); C204(0.64); C147(0.94)  LDD0602  [4]
 LDCM0286  AC26 HCT 116 C292(0.44); C293(0.44); C204(0.60); C147(0.63)  LDD0603  [4]
 LDCM0287  AC27 HCT 116 C292(0.28); C293(0.28); C147(0.51); C149(0.51)  LDD0604  [4]
 LDCM0288  AC28 HCT 116 C292(0.32); C293(0.32); C147(0.56); C149(0.56)  LDD0605  [4]
 LDCM0289  AC29 HCT 116 C292(0.41); C293(0.41); C147(0.60); C149(0.60)  LDD0606  [4]
 LDCM0290  AC3 HCT 116 C292(0.56); C293(0.56); C204(0.58); C147(0.69)  LDD0607  [4]
 LDCM0291  AC30 HCT 116 C292(0.28); C293(0.28); C147(0.53); C149(0.53)  LDD0608  [4]
 LDCM0292  AC31 HCT 116 C292(0.38); C293(0.38); C204(0.63); C147(0.77)  LDD0609  [4]
 LDCM0293  AC32 HCT 116 C292(0.13); C293(0.13); C147(0.26); C149(0.26)  LDD0610  [4]
 LDCM0294  AC33 HCT 116 C292(0.18); C293(0.18); C147(0.29); C149(0.29)  LDD0611  [4]
 LDCM0295  AC34 HCT 116 C292(0.13); C293(0.13); C147(0.23); C149(0.23)  LDD0612  [4]
 LDCM0296  AC35 HCT 116 C147(1.53); C149(1.53); C393(1.64); C292(1.88)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C147(1.34); C149(1.34); C292(1.83); C293(1.83)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C393(1.31); C292(1.52); C293(1.52); C147(1.64)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C393(1.20); C292(1.32); C293(1.32); C147(1.33)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C292(0.91); C293(0.91); C147(0.93); C149(0.93)  LDD0617  [4]
 LDCM0301  AC4 HCT 116 C147(0.45); C149(0.45); C292(0.49); C293(0.49)  LDD0618  [4]
 LDCM0302  AC40 HCT 116 C147(0.70); C149(0.70); C292(0.70); C293(0.70)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C393(0.88); C147(1.05); C149(1.05); C292(1.16)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C393(0.84); C292(0.89); C293(0.89); C147(0.91)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C393(0.87); C292(1.15); C293(1.15); C147(1.20)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C292(0.75); C293(0.75); C393(0.86); C147(0.89)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C292(0.59); C293(0.59); C147(0.81); C149(0.81)  LDD0624  [4]
 LDCM0308  AC46 HCT 116 C292(0.60); C293(0.60); C393(0.78); C204(1.01)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C292(0.63); C293(0.63); C147(0.85); C149(0.85)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C292(0.62); C293(0.62); C393(0.79); C204(0.99)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C147(0.60); C149(0.60); C393(0.70); C292(0.88)  LDD0628  [4]
 LDCM0312  AC5 HCT 116 C147(0.48); C149(0.48); C292(0.49); C293(0.49)  LDD0629  [4]
 LDCM0313  AC50 HCT 116 C292(0.59); C293(0.59); C147(0.60); C149(0.60)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C292(0.75); C293(0.75); C393(0.91); C204(0.97)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C292(0.74); C293(0.74); C204(0.82); C147(0.84)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C147(0.57); C149(0.57); C292(0.72); C293(0.72)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C147(0.55); C149(0.55); C292(0.69); C293(0.69)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C147(0.60); C149(0.60); C292(0.99); C293(0.99)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C147(0.79); C149(0.79); C292(0.91); C293(0.91)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C147(0.31); C149(0.31); C204(0.68); C292(1.03)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C147(0.33); C149(0.33); C204(0.95); C292(1.18)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C147(0.26); C149(0.26); C204(0.80); C292(0.92)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C147(0.37); C149(0.37); C292(0.42); C293(0.42)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C147(0.48); C149(0.48); C204(0.85); C292(0.88)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C204(0.82); C147(0.83); C149(0.83); C292(1.08)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C147(0.23); C149(0.23); C204(0.85); C292(0.86)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C147(0.34); C149(0.34); C204(0.86); C292(1.01)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C147(0.25); C149(0.25); C204(0.81); C292(1.00)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C147(0.31); C149(0.31); C204(0.72); C292(0.96)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C147(0.34); C149(0.34); C204(0.91); C292(1.40)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C147(0.22); C149(0.22); C204(0.74); C292(0.93)  LDD0648  [4]
 LDCM0332  AC68 HCT 116 C147(0.54); C149(0.54); C393(0.90)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C147(0.50); C149(0.50); C393(0.81)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C147(0.51); C149(0.51); C292(0.68); C293(0.68)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C147(0.44); C149(0.44); C393(0.86)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C393(0.99); C147(1.05); C149(1.05)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C147(0.44); C149(0.44); C393(0.94)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C147(0.45); C149(0.45); C393(0.94)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C147(0.45); C149(0.45); C393(1.20)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C147(0.54); C149(0.54); C393(0.99)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C147(0.34); C149(0.34); C393(1.00)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C147(0.33); C149(0.33); C393(0.95)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C393(1.00); C147(1.52); C149(1.52)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C147(0.66); C149(0.66); C393(0.84)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C292(0.48); C293(0.48); C147(0.63); C149(0.63)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C147(0.51); C149(0.51); C393(0.94)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C393(0.98); C147(1.26); C149(1.26)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C147(0.55); C149(0.55); C393(0.82)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C292(0.19); C293(0.19); C147(0.34); C149(0.34)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C292(0.21); C293(0.21); C147(0.36); C149(0.36)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C204(0.65); C292(0.78); C293(0.78); C147(0.94)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C292(0.44); C293(0.44); C204(0.64); C147(0.67)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C204(0.87); C147(1.00); C149(1.00); C393(1.01)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C292(0.61); C293(0.61); C204(0.64); C147(0.81)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C292(0.27); C293(0.27); C147(0.42); C149(0.42)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C204(0.89); C147(0.93); C149(0.93); C393(0.94)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C292(0.18); C293(0.18); C147(0.34); C149(0.34)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C292(0.18); C293(0.18); C147(0.32); C149(0.32)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C292(0.47); C293(0.47); C147(0.63); C149(0.63)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C204(0.62); C147(1.15); C149(1.15); C292(1.17)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C393(1.05); C147(1.05); C149(1.05); C292(1.11)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C292(0.43); C293(0.43); C147(0.60); C149(0.60)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C292(0.22); C293(0.22); C147(0.38); C149(0.38)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C147(0.15); C149(0.15); C292(0.38); C293(0.38)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C147(0.51); C149(0.51); C393(0.76); C204(0.77)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C147(0.66); C149(0.66); C204(0.78); C292(0.93)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C147(0.54); C149(0.54); C292(0.62); C293(0.62)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C292(0.11); C293(0.11); C147(0.13); C149(0.13)  LDD0592  [4]
 LDCM0156  Aniline NCI-H1299 13.69  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C204(0.93)  LDD0078  [4]
 LDCM0108  Chloroacetamide HeLa C33(0.00); C316(0.00)  LDD0222  [10]
 LDCM0367  CL1 HCT 116 C393(1.04); C204(1.06); C292(1.82); C293(1.82)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C292(0.58); C293(0.58); C204(0.96); C393(1.35)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C147(0.37); C149(0.37); C292(0.44); C293(0.44)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C292(0.34); C293(0.34); C147(0.48); C149(0.48)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C147(0.59); C149(0.59); C292(0.68); C293(0.68)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C147(0.46); C149(0.46); C292(0.65); C293(0.65)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C292(0.70); C293(0.70); C147(0.73); C149(0.73)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C292(0.35); C293(0.35); C147(0.49); C149(0.49)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C292(0.21); C293(0.21); C147(0.38); C149(0.38)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C292(0.14); C293(0.14); C147(0.25); C149(0.25)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C292(0.12); C293(0.12); C147(0.21); C149(0.21)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C292(0.35); C293(0.35); C147(0.52); C149(0.52)  LDD0695  [4]
 LDCM0379  CL11 HCT 116 C292(0.45); C293(0.45); C393(0.82); C204(1.24)  LDD0696  [4]
 LDCM0380  CL110 HCT 116 C292(0.23); C293(0.23); C147(0.42); C149(0.42)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C292(0.54); C293(0.54); C393(0.69); C147(0.71)  LDD0698  [4]
 LDCM0382  CL112 HCT 116 C292(0.75); C293(0.75); C204(0.82); C393(0.89)  LDD0699  [4]
 LDCM0383  CL113 HCT 116 C292(0.17); C293(0.17); C147(0.30); C149(0.30)  LDD0700  [4]
 LDCM0384  CL114 HCT 116 C292(0.65); C293(0.65); C147(0.67); C149(0.67)  LDD0701  [4]
 LDCM0385  CL115 HCT 116 C292(0.35); C293(0.35); C147(0.63); C149(0.63)  LDD0702  [4]
 LDCM0386  CL116 HCT 116 C292(0.37); C293(0.37); C147(0.58); C149(0.58)  LDD0703  [4]
 LDCM0387  CL117 HCT 116 C292(0.66); C293(0.66); C147(0.75); C149(0.75)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C292(0.72); C293(0.72); C147(0.91); C149(0.91)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C292(0.67); C293(0.67); C393(0.77); C147(0.83)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C292(0.41); C293(0.41); C204(1.07); C393(1.08)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C292(0.95); C293(0.95); C393(1.02); C147(1.14)  LDD0708  [4]
 LDCM0392  CL121 HCT 116 C292(0.73); C293(0.73); C393(0.75); C204(0.87)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C292(0.89); C293(0.89); C204(0.92); C147(1.02)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C147(0.63); C149(0.63); C292(0.81); C293(0.81)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C147(0.55); C149(0.55); C292(0.68); C293(0.68)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C204(0.67); C292(0.87); C293(0.87); C147(1.22)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C204(1.01); C292(1.02); C293(1.02); C147(1.07)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C147(0.76); C149(0.76); C204(0.82); C292(1.02)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C147(0.24); C149(0.24); C204(0.75); C292(1.11)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C292(0.79); C293(0.79); C393(1.03); C204(1.11)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C292(0.88); C293(0.88); C393(1.00); C204(1.20)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C393(0.97); C204(1.29); C292(1.32); C293(1.32)  LDD0719  [4]
 LDCM0403  CL16 HCT 116 C292(0.63); C293(0.63); C147(0.79); C149(0.79)  LDD0720  [4]
 LDCM0404  CL17 HCT 116 C393(0.71); C147(0.89); C149(0.89); C204(0.92)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C204(0.87); C393(0.92); C292(1.17); C293(1.17)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C292(0.65); C293(0.65); C204(0.96); C147(0.99)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C204(0.96); C393(1.32); C292(2.32); C293(2.32)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C292(0.21); C293(0.21); C147(0.29); C149(0.29)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C292(0.21); C293(0.21); C147(0.30); C149(0.30)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C292(0.20); C293(0.20); C147(0.36); C149(0.36)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C292(0.29); C293(0.29); C147(0.39); C149(0.39)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C292(0.19); C293(0.19); C147(0.35); C149(0.35)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C147(0.27); C149(0.27); C204(0.76); C292(0.19)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C147(0.59); C149(0.59); C204(0.86); C292(0.32)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C147(0.49); C149(0.49); C204(0.84); C292(0.30)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C147(0.42); C149(0.42); C204(0.76); C292(0.28)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C147(0.38); C149(0.38); C204(0.91); C292(0.25)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C204(0.92); C292(1.22); C293(1.22); C393(1.09)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C147(1.20); C149(1.20); C204(0.85); C292(0.62)  LDD0736  [4]
 LDCM0420  CL31 HCT 116 C147(0.74); C149(0.74); C204(0.90); C292(0.59)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C147(1.59); C149(1.59); C204(1.75); C292(1.03)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C147(0.64); C149(0.64); C204(0.97); C292(0.95)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C147(0.25); C149(0.25); C204(1.52); C292(0.21)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C147(0.26); C149(0.26); C204(1.43); C292(0.21)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C147(0.30); C149(0.30); C204(1.38); C292(0.20)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C147(0.27); C149(0.27); C204(1.52); C292(0.19)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C147(0.26); C149(0.26); C204(1.37); C292(0.19)  LDD0745  [4]
 LDCM0429  CL4 HCT 116 C204(0.96); C292(0.97); C293(0.97); C393(1.48)  LDD0746  [4]
 LDCM0430  CL40 HCT 116 C147(0.30); C149(0.30); C204(1.26); C292(0.21)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C147(0.32); C149(0.32); C204(1.19); C292(0.21)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C147(0.35); C149(0.35); C204(1.64); C292(0.21)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C147(0.29); C149(0.29); C204(1.61); C292(0.22)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C147(0.39); C149(0.39); C204(1.62); C292(0.37)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C147(0.36); C149(0.36); C204(1.55); C292(0.21)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C204(0.85); C292(2.11); C293(2.11); C393(0.90)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C204(0.94); C292(1.66); C293(1.66); C393(0.75)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C204(0.87); C292(1.84); C293(1.84); C393(0.65)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C204(0.88); C292(0.91); C293(0.91); C393(0.88)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C204(1.08); C292(0.86); C293(0.86); C393(1.41)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C204(0.91); C292(1.52); C293(1.52); C393(0.80)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C204(0.84); C292(1.39); C293(1.39); C393(0.82)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C204(0.94); C292(1.49); C293(1.49); C393(0.89)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C204(1.19); C292(1.71); C293(1.71); C393(0.57)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C204(0.99); C292(1.56); C293(1.56); C393(0.69)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C204(0.90); C292(1.66); C293(1.66); C393(1.01)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C204(1.11); C292(0.97); C293(0.97); C393(0.68)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C204(1.15); C292(1.69); C293(1.69); C393(0.64)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C204(0.96); C292(1.83); C293(1.83); C393(1.13)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C204(0.99); C292(1.07); C293(1.07); C393(1.14)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C204(1.17); C292(1.56); C293(1.56); C393(1.05)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C204(1.00); C292(1.16); C293(1.16); C393(0.80)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C147(0.77); C149(0.77); C204(0.96); C292(0.78)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C147(0.55); C149(0.55); C204(1.00); C292(0.72)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C147(0.36); C149(0.36); C204(0.77); C292(0.59)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C147(0.20); C149(0.20); C204(0.97); C292(0.51)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C147(0.55); C149(0.55); C204(0.80); C292(0.76)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C147(0.12); C149(0.12); C204(0.87); C292(0.41)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C147(0.16); C149(0.16); C204(0.84); C292(0.68)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C147(0.48); C149(0.48); C204(0.82); C292(0.93)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C147(1.82); C149(1.82); C204(1.60); C292(1.07)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C204(1.15); C292(0.50); C293(0.50); C393(1.05)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C147(0.35); C149(0.35); C204(0.94); C292(0.80)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C147(0.23); C149(0.23); C204(0.78); C292(0.56)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C147(0.81); C149(0.81); C204(0.69); C292(0.81)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C147(0.31); C149(0.31); C204(1.38); C292(0.74)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C147(0.24); C149(0.24); C204(1.14); C292(0.71)  LDD0784  [4]
 LDCM0469  CL76 HCT 116 C147(0.75); C149(0.75); C204(1.04); C292(1.19)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C147(1.25); C149(1.25); C204(1.58); C292(1.17)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C147(0.61); C149(0.61); C204(0.93); C292(0.80)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C147(0.26); C149(0.26); C204(1.22); C292(0.67)  LDD0789  [4]
 LDCM0473  CL8 HCT 116 C204(1.57); C292(0.49); C293(0.49); C393(1.19)  LDD0790  [4]
 LDCM0474  CL80 HCT 116 C147(1.61); C149(1.61); C204(1.81); C292(1.21)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C147(0.46); C149(0.46); C204(1.01); C292(0.69)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C147(0.27); C149(0.27); C204(1.30); C292(0.56)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C147(0.30); C149(0.30); C204(1.23); C292(0.59)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C147(0.32); C149(0.32); C204(1.48); C292(0.49)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C147(0.52); C149(0.52); C204(0.99); C292(0.74)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C147(0.73); C149(0.73); C204(0.91); C292(0.90)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C147(0.46); C149(0.46); C204(0.92); C292(0.71)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C147(0.27); C149(0.27); C204(1.13); C292(0.79)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C147(0.40); C149(0.40); C204(1.36); C292(0.65)  LDD0800  [4]
 LDCM0484  CL9 HCT 116 C204(1.24); C292(0.66); C293(0.66); C393(1.25)  LDD0801  [4]
 LDCM0485  CL90 HCT 116 C147(0.81); C149(0.81); C204(1.23); C292(1.37)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C147(0.53); C149(0.53); C204(0.59); C292(0.67)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C147(0.61); C149(0.61); C204(0.75); C292(0.75)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C147(0.77); C149(0.77); C204(0.89); C292(0.69)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C147(0.45); C149(0.45); C204(0.73); C292(0.50)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C147(0.40); C149(0.40); C204(0.69); C292(0.60)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C147(0.42); C149(0.42); C204(0.64); C292(0.48)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C147(0.49); C149(0.49); C204(0.77); C292(0.48)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C147(0.38); C149(0.38); C204(0.63); C292(0.45)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C147(0.42); C149(0.42); C204(0.62); C292(0.48)  LDD0811  [4]
 LDCM0495  E2913 HEK-293T C393(0.95); C316(1.00); C204(1.04); C293(1.05)  LDD1698  [15]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C204(2.11); C33(1.18)  LDD1702  [16]
 LDCM0625  F8 Ramos C204(0.73)  LDD2187  [17]
 LDCM0576  Fragment14 Ramos C204(0.48)  LDD2193  [17]
 LDCM0468  Fragment33 HCT 116 C147(0.33); C149(0.33); C204(0.73); C292(0.55)  LDD0785  [4]
 LDCM0566  Fragment4 Ramos C204(0.83)  LDD2184  [17]
 LDCM0427  Fragment51 HCT 116 C147(0.31); C149(0.31); C204(1.70); C292(0.19)  LDD0744  [4]
 LDCM0569  Fragment7 Ramos C204(0.75)  LDD2186  [17]
 LDCM0107  IAA HeLa H19(0.00); C316(0.00)  LDD0221  [10]
 LDCM0022  KB02 HCT 116 C204(1.59)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C204(2.37)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C204(1.49)  LDD0082  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C33(0.90)  LDD2206  [18]
 LDCM0021  THZ1 HCT 116 C204(1.16)  LDD2173  [4]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
10 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
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12 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
13 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
14 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
16 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
17 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
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