Details of the Probe

General Information of Probe

Probe ID
LDPC0585
Probe Name
C364
Synonyms
Z4225949754
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 332.8
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C15H13ClN4OS
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-6-chlorothieno[3,2-b]pyridine-3-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2=CSC3=C2N=CC(=C3)Cl
InChI
InChI=1S/C15H13ClN4OS/c1-2-3-4-15(19-20-15)5-6-17-14(21)11-9-22-12-7-10(16)8-18-13(11)12/h1,7-9H,3-6H2,(H,17,21)
InChIKey
LZBMEAOMNUPVFB-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

117 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 27.67  LDD2025 
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (COQ5) LDTP06988 17.03  LDD2025 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 18.25  LDD2025 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 16.45  LDD2025 
Abasic site processing protein HMCES (HMCES) LDTP10322 20.11  LDD2025 
Acid ceramidase (ASAH1) LDTP05905 31.78  LDD2025 
Adenosine deaminase (ADA) LDTP01803 51.63  LDD2025 
Adenosine kinase (ADK) LDTP04689 14.83  LDD2025 
ADP-dependent glucokinase (ADPGK) LDTP11127 26.35  LDD2025 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 56.49  LDD2025 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 27.67  LDD2025 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 22.63  LDD2025 
Atlastin-2 (ATL2) LDTP09251 20.53  LDD2025 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 16.34  LDD2025 
Beta-glucuronidase (GUSB) LDTP02260 15.35  LDD2025 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 31.78  LDD2025 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 41.64  LDD2025 
Cartilage-associated protein (CRTAP) LDTP01300 31.34  LDD2025 
Catechol O-methyltransferase (COMT) LDTP03145 50.91  LDD2025 
Cathepsin B (CTSB) LDTP02223 19.97  LDD2025 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 49.87  LDD2025 
Ceramide glucosyltransferase (UGCG) LDTP06617 23.10  LDD2025 
Ceramide synthase 2 (CERS2) LDTP10329 35.51  LDD2025 
Choline kinase alpha (CHKA) LDTP03787 22.01  LDD2025 
COP9 signalosome complex subunit 5 (COPS5) LDTP09925 15.03  LDD2025 
Creatine kinase B-type (CKB) LDTP02616 16.45  LDD2025 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 19.97  LDD2025 
Cytochrome b5 type B (CYB5B) LDTP00697 79.89  LDD2025 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 25.28  LDD2025 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 20.82  LDD2025 
DCN1-like protein 4 (DCUN1D4) LDTP09799 44.94  LDD2025 
DCN1-like protein 5 (DCUN1D5) LDTP11199 21.86  LDD2025 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 18.13  LDD2025 
Delta(24)-sterol reductase (DHCR24) LDTP06375 22.78  LDD2025 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 16.56  LDD2025 
Dihydrofolate reductase (DHFR) LDTP01769 15.24  LDD2025 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 17.63  LDD2025 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 15.14  LDD2025 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 35.26  LDD2025 
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) LDTP03170 17.15  LDD2025 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 16.22  LDD2025 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 21.26  LDD2025 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 23.26  LDD2025 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 25.63  LDD2025 
Epoxide hydrolase 1 (EPHX1) LDTP02175 17.27  LDD2025 
Ethanolamine kinase 1 (ETNK1) LDTP12197 65.80  LDD2025 
Ferrochelatase, mitochondrial (FECH) LDTP03198 37.27  LDD2025 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 36.50  LDD2025 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 21.86  LDD2025 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 15.24  LDD2025 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 22.01  LDD2025 
Heme oxygenase 1 (HMOX1) LDTP02359 68.59  LDD2025 
Heme oxygenase 2 (HMOX2) LDTP03540 66.72  LDD2025 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 16.34  LDD2025 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 30.70  LDD2025 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 37.01  LDD2025 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 17.39  LDD2025 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 14.83  LDD2025 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 19.03  LDD2025 
Lysosomal acid phosphatase (ACP2) LDTP02539 19.56  LDD2025 
Lysosomal alpha-glucosidase (GAA) LDTP02486 20.82  LDD2025 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 30.91  LDD2025 
Macrophage migration inhibitory factor (MIF) LDTP02713 50.91  LDD2025 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 14.93  LDD2025 
Minor histocompatibility antigen H13 (HM13) LDTP09396 16.34  LDD2025 
Mitochondrial ribonuclease P catalytic subunit (PRORP) LDTP00536 18.00  LDD2025 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 26.91  LDD2025 
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) LDTP00837 16.00  LDD2025 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 15.03  LDD2025 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 22.16  LDD2025 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 53.08  LDD2025 
NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial (NDUFB5) LDTP00831 17.63  LDD2025 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 18.25  LDD2025 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 32.90  LDD2025 
NADP-dependent malic enzyme (ME1) LDTP04164 14.83  LDD2025 
Oligoribonuclease, mitochondrial (REXO2) LDTP13972 17.03  LDD2025 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 99.73  LDD2025 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 17.63  LDD2025 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 19.03  LDD2025 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 14.83  LDD2025 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 25.46  LDD2025 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 63.56  LDD2025 
Phosphoglucomutase-1 (PGM1) LDTP03818 18.25  LDD2025 
Phospholipase A-2-activating protein (PLAA) LDTP13814 27.10  LDD2025 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 18.51  LDD2025 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 16.56  LDD2025 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 17.51  LDD2025 
Procathepsin L (CTSL) LDTP02217 25.28  LDD2025 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 16.45  LDD2025 
Prostaglandin reductase 3 (PTGR3) LDTP15422 25.11  LDD2025 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 18.00  LDD2025 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 23.75  LDD2025 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 17.75  LDD2025 
Protein arginine N-methyltransferase 9 (PRMT9) LDTP07525 24.59  LDD2025 
Protein O-GlcNAcase (OGA) LDTP00988 20.53  LDD2025 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 36.76  LDD2025 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 41.64  LDD2025 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 21.86  LDD2025 
Ras-related protein Rab-1B (RAB1B) LDTP11733 16.68  LDD2025 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 27.67  LDD2025 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 39.40  LDD2025 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 42.22  LDD2025 
Serine/threonine-protein kinase TAO1 (TAOK1) LDTP07975 21.26  LDD2025 
Serine/threonine-protein kinase TAO2 (TAOK2) LDTP13523 22.16  LDD2025 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 20.25  LDD2025 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 46.85  LDD2025 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 19.70  LDD2025 
Squalene synthase (FDFT1) LDTP03842 15.03  LDD2025 
Sulfhydryl oxidase 2 (QSOX2) LDTP07813 14.83  LDD2025 
Terminal uridylyltransferase 4 (TUT4) LDTP07171 17.27  LDD2025 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 18.25  LDD2025 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 25.81  LDD2025 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 19.16  LDD2025 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 23.75  LDD2025 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 16.11  LDD2025 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 15.24  LDD2025 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 23.92  LDD2025 
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⏷ Show the Full List of 117 Enzyme
92 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 21.11  LDD2025 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 65.80  LDD2025 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 30.48  LDD2025 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 21.56  LDD2025 
ATP synthase subunit a (MT-ATP6) LDTP01804 99.73  LDD2025 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 40.50  LDD2025 
BOS complex subunit NCLN (NCLN) LDTP10036 18.90  LDD2025 
BRI3-binding protein (BRI3BP) LDTP15648 28.84  LDD2025 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 15.89  LDD2025 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 26.54  LDD2025 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 19.84  LDD2025 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 41.64  LDD2025 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 30.06  LDD2025 
Derlin-1 (DERL1) LDTP11245 35.75  LDD2025 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 18.00  LDD2025 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 43.41  LDD2025 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 66.26  LDD2025 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 28.64  LDD2025 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 31.56  LDD2025 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 50.21  LDD2025 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 46.85  LDD2025 
Integral membrane protein 2C (ITM2C) LDTP12451 23.92  LDD2025 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 16.11  LDD2025 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 29.65  LDD2025 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 99.04  LDD2025 
Lysosome membrane protein 2 (SCARB2) LDTP06034 28.64  LDD2025 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 74.54  LDD2025 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 29.86  LDD2025 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 80.45  LDD2025 
Metaxin-1 (MTX1) LDTP05900 27.10  LDD2025 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 17.88  LDD2025 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 14.93  LDD2025 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 26.54  LDD2025 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 37.53  LDD2025 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 58.49  LDD2025 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 40.22  LDD2025 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 57.68  LDD2025 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 50.91  LDD2025 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 18.77  LDD2025 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 28.25  LDD2025 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 48.17  LDD2025 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 24.59  LDD2025 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 23.59  LDD2025 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 17.75  LDD2025 
Mpv17-like protein 2 (MPV17L2) LDTP14952 16.80  LDD2025 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 22.63  LDD2025 
Nucleoporin Nup37 (NUP37) LDTP09203 18.00  LDD2025 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 15.67  LDD2025 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 17.39  LDD2025 
Peroxisomal membrane protein 11A (PEX11A) LDTP01160 16.68  LDD2025 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 17.39  LDD2025 
PRA1 family protein 2 (PRAF2) LDTP01060 17.51  LDD2025 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 24.93  LDD2025 
Prosaposin (PSAP) LDTP02215 50.21  LDD2025 
Protein GPR107 (GPR107) LDTP07236 27.86  LDD2025 
Protein GPR108 (GPR108) LDTP12383 32.00  LDD2025 
Protein spinster homolog 1 (SPNS1) LDTP11844 43.11  LDD2025 
Protein tweety homolog 3 (TTYH3) LDTP11615 18.77  LDD2025 
Protein YIPF3 (YIPF3) LDTP11626 23.59  LDD2025 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 50.56  LDD2025 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 16.22  LDD2025 
Renin receptor (ATP6AP2) LDTP01309 18.13  LDD2025 
Reticulon-1 (RTN1) LDTP06633 14.83  LDD2025 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 17.88  LDD2025 
RNA-binding protein with serine-rich domain 1 (RNPS1) LDTP06350 15.14  LDD2025 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 20.11  LDD2025 
Sideroflexin-4 (SFXN4) LDTP07531 20.82  LDD2025 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 20.53  LDD2025 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 99.73  LDD2025 
Sorting nexin-2 (SNX2) LDTP01043 28.44  LDD2025 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 18.00  LDD2025 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 31.12  LDD2025 
Stomatin (STOM) LDTP03380 17.15  LDD2025 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 20.68  LDD2025 
Syntaxin-6 (STX6) LDTP00857 23.59  LDD2025 
Tetraspanin-3 (TSPAN3) LDTP16813 80.45  LDD2025 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 46.85  LDD2025 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 53.08  LDD2025 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 21.26  LDD2025 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 42.81  LDD2025 
Transmembrane protein 126A (TMEM126A) LDTP15948 56.89  LDD2025 
Transmembrane protein 160 (TMEM160) LDTP20002 66.26  LDD2025 
Transmembrane protein 199 (TMEM199) LDTP08881 28.84  LDD2025 
Transmembrane protein 205 (TMEM205) LDTP07667 19.43  LDD2025 
Transmembrane protein 214 (TMEM214) LDTP07477 19.43  LDD2025 
Transmembrane protein 230 (TMEM230) LDTP10065 31.34  LDD2025 
Transmembrane protein 33 (TMEM33) LDTP04787 16.11  LDD2025 
Transmembrane protein 87A (TMEM87A) LDTP15481 21.26  LDD2025 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 24.08  LDD2025 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 33.82  LDD2025 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 36.50  LDD2025 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 31.78  LDD2025 
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⏷ Show the Full List of 92 Transporter and channel
4 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 18.13  LDD2025 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 19.70  LDD2025 
Y-box-binding protein 1 (YBX1) LDTP05065 18.00  LDD2025 
Y-box-binding protein 3 (YBX3) LDTP02870 20.39  LDD2025 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 15.03  LDD2025 
Leukocyte surface antigen CD47 (CD47) LDTP05572 30.70  LDD2025 
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103 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenomatous polyposis coli protein (APC) LDTP03303 15.45  LDD2025 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 21.71  LDD2025 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 15.89  LDD2025 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD2025 
Arfaptin-2 (ARFIP2) LDTP04557 18.64  LDD2025 
Calmodulin-3 (CALM3) LDTP02443 14.93  LDD2025 
Calumenin (CALU) LDTP00887 16.56  LDD2025 
Centrin-2 (CETN2) LDTP03926 29.04  LDD2025 
Clustered mitochondria protein homolog (CLUH) LDTP14486 22.32  LDD2025 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 15.67  LDD2025 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 14.83  LDD2025 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 16.68  LDD2025 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 21.56  LDD2025 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD2025 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 24.59  LDD2025 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 14.83  LDD2025 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 68.59  LDD2025 
DNA replication complex GINS protein PSF3 (GINS3) LDTP11139 16.11  LDD2025 
Dynactin subunit 3 (DCTN3) LDTP01359 19.03  LDD2025 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 24.59  LDD2025 
Emerin (EMD) LDTP04356 16.56  LDD2025 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 19.16  LDD2025 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 16.00  LDD2025 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 30.91  LDD2025 
Endothelial differentiation-related factor 1 (EDF1) LDTP01067 15.78  LDD2025 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 50.56  LDD2025 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 26.35  LDD2025 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 17.39  LDD2025 
Formin-binding protein 1 (FNBP1) LDTP10786 39.67  LDD2025 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 26.35  LDD2025 
Ganglioside GM2 activator (GM2A) LDTP02927 24.08  LDD2025 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 25.11  LDD2025 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 18.25  LDD2025 
Golgi apparatus protein 1 (GLG1) LDTP09920 16.34  LDD2025 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 24.42  LDD2025 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 15.45  LDD2025 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 17.15  LDD2025 
HCLS1-associated protein X-1 (HAX1) LDTP00199 17.03  LDD2025 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 29.04  LDD2025 
Integral membrane protein GPR180 (GPR180) LDTP19625 24.25  LDD2025 
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA) LDTP01259 20.11  LDD2025 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 23.43  LDD2025 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 25.28  LDD2025 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 25.99  LDD2025 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 26.17  LDD2025 
Large proline-rich protein BAG6 (BAG6) LDTP04094 17.75  LDD2025 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 47.50  LDD2025 
LYR motif-containing protein 2 (LYRM2) LDTP18467 33.82  LDD2025 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 18.90  LDD2025 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 18.90  LDD2025 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 30.06  LDD2025 
Mitochondrial fission regulator 2 (MTFR2) LDTP15112 21.86  LDD2025 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 21.41  LDD2025 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 64.00  LDD2025 
Negative elongation factor C/D (NELFCD) LDTP08594 36.00  LDD2025 
Neuferricin (CYB5D2) LDTP15623 15.14  LDD2025 
Neurofilament light polypeptide (NEFL) LDTP02180 17.51  LDD2025 
Neurofilament medium polypeptide (NEFM) LDTP02181 15.35  LDD2025 
Nucleobindin-2 (NUCB2) LDTP05160 33.82  LDD2025 
Nurim (NRM) LDTP08606 24.42  LDD2025 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 24.42  LDD2025 
Optic atrophy 3 protein (OPA3) LDTP16006 49.87  LDD2025 
Oxysterol-binding protein-related protein 2 (OSBPL2) LDTP11774 18.64  LDD2025 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 22.01  LDD2025 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 38.32  LDD2025 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 25.28  LDD2025 
Prefoldin subunit 6 (PFDN6) LDTP00573 17.75  LDD2025 
Programmed cell death protein 5 (PDCD5) LDTP00417 16.56  LDD2025 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 15.35  LDD2025 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 15.78  LDD2025 
Protein CutA (CUTA) LDTP01075 14.83  LDD2025 
Protein ecdysoneless homolog (ECD) LDTP01711 14.93  LDD2025 
Protein FAM114A2 (FAM114A2) LDTP16080 21.71  LDD2025 
Protein FAM162A (FAM162A) LDTP10056 64.45  LDD2025 
Protein Hook homolog 2 (HOOK2) LDTP10255 20.11  LDD2025 
Protein jagunal homolog 1 (JAGN1) LDTP08904 15.14  LDD2025 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 31.12  LDD2025 
Protein LYRIC (MTDH) LDTP08224 16.34  LDD2025 
Protein YIF1A (YIF1A) LDTP01494 18.00  LDD2025 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 15.89  LDD2025 
Reticulocalbin-2 (RCN2) LDTP06097 17.75  LDD2025 
Reticulon-3 (RTN3) LDTP01522 47.50  LDD2025 
Reticulon-4 (RTN4) LDTP12412 34.30  LDD2025 
RNA-binding protein 3 (RBM3) LDTP05226 17.51  LDD2025 
RNA-binding protein FXR1 (FXR1) LDTP04395 17.03  LDD2025 
RNA-binding protein FXR2 (FXR2) LDTP04396 16.34  LDD2025 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 36.00  LDD2025 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 20.25  LDD2025 
Synaptogyrin-2 (SYNGR2) LDTP00859 15.56  LDD2025 
Syntaxin-10 (STX10) LDTP00986 47.18  LDD2025 
Syntaxin-18 (STX18) LDTP13086 99.73  LDD2025 
Syntaxin-7 (STX7) LDTP00632 16.80  LDD2025 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 23.92  LDD2025 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 18.90  LDD2025 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 36.25  LDD2025 
TraB domain-containing protein (TRABD) LDTP19963 29.65  LDD2025 
Trophoblast glycoprotein (TPBG) LDTP05960 24.93  LDD2025 
Tubulin-specific chaperone D (TBCD) LDTP11212 18.13  LDD2025 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 29.86  LDD2025 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 58.89  LDD2025 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 16.91  LDD2025 
Vimentin (VIM) LDTP02297 23.43  LDD2025 
Zinc finger CCCH domain-containing protein 7B (ZC3H7B) LDTP13245 15.78  LDD2025 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2025 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587