Details of the Probe

General Information of Probe

Probe ID
LDPC0583
Probe Name
C362
Synonyms
Z4225929305
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 348.4
Lipid-water partition coefficient (xlogp) 3.4
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H20N4O2
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-5-cyclopropyl-2-phenyl-1,3-oxazole-4-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2=C(OC(=N2)C3=CC=CC=C3)C4CC4
InChI
InChI=1S/C20H20N4O2/c1-2-3-11-20(23-24-20)12-13-21-18(25)16-17(14-9-10-14)26-19(22-16)15-7-5-4-6-8-15/h1,4-8,14H,3,9-13H2,(H,21,25)
InChIKey
IEVKIWKVJRJURN-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

164 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 25.81  LDD2023 
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 49.18  LDD2023 
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (COQ5) LDTP06988 43.71  LDD2023 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 35.26  LDD2023 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 30.70  LDD2023 
Abasic site processing protein HMCES (HMCES) LDTP10322 38.59  LDD2023 
Acid ceramidase (ASAH1) LDTP05905 68.12  LDD2023 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 29.04  LDD2023 
Acyl-coenzyme A thioesterase 8 (ACOT8) LDTP00415 26.54  LDD2023 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 31.12  LDD2023 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 25.46  LDD2023 
Adenosine deaminase (ADA) LDTP01803 92.41  LDD2023 
ADP-dependent glucokinase (ADPGK) LDTP11127 99.73  LDD2023 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 99.73  LDD2023 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 25.81  LDD2023 
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT2) LDTP05622 31.78  LDD2023 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 49.52  LDD2023 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 39.67  LDD2023 
Atlastin-2 (ATL2) LDTP09251 69.55  LDD2023 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 39.95  LDD2023 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 47.18  LDD2023 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 28.84  LDD2023 
ATPase GET3 (GET3) LDTP00836 38.05  LDD2023 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 45.25  LDD2023 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 29.04  LDD2023 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 99.73  LDD2023 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 26.54  LDD2023 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 99.73  LDD2023 
Cartilage-associated protein (CRTAP) LDTP01300 30.06  LDD2023 
Catechol O-methyltransferase (COMT) LDTP03145 72.00  LDD2023 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 99.73  LDD2023 
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) LDTP00416 28.84  LDD2023 
Ceramide glucosyltransferase (UGCG) LDTP06617 41.64  LDD2023 
Ceramide synthase 2 (CERS2) LDTP10329 99.73  LDD2023 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 44.32  LDD2023 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 31.34  LDD2023 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 54.19  LDD2023 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD2023 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 69.55  LDD2023 
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) LDTP14427 25.81  LDD2023 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 91.77  LDD2023 
DCN1-like protein 4 (DCUN1D4) LDTP09799 88.65  LDD2023 
DCN1-like protein 5 (DCUN1D5) LDTP11199 41.93  LDD2023 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 30.48  LDD2023 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 33.13  LDD2023 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 30.91  LDD2023 
Delta(24)-sterol reductase (DHCR24) LDTP06375 31.12  LDD2023 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 68.59  LDD2023 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 63.12  LDD2023 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 35.26  LDD2023 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 39.40  LDD2023 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 31.78  LDD2023 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 25.99  LDD2023 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 28.84  LDD2023 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 42.22  LDD2023 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 35.75  LDD2023 
Enoyl-CoA delta isomerase 1, mitochondrial (ECI1) LDTP03965 25.28  LDD2023 
Epoxide hydrolase 1 (EPHX1) LDTP02175 55.72  LDD2023 
Ethanolamine kinase 1 (ETNK1) LDTP12197 51.98  LDD2023 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 42.52  LDD2023 
Ferrochelatase, mitochondrial (FECH) LDTP03198 39.67  LDD2023 
Glutathione hydrolase 7 (GGT7) LDTP13367 37.01  LDD2023 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 40.50  LDD2023 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 29.65  LDD2023 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 70.52  LDD2023 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 42.81  LDD2023 
GTP-binding protein 8 (GTPBP8) LDTP17699 31.56  LDD2023 
GTP-binding protein SAR1a (SAR1A) LDTP12470 28.64  LDD2023 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 99.73  LDD2023 
Heme A synthase COX15 (COX15) LDTP07931 52.35  LDD2023 
Heme oxygenase 1 (HMOX1) LDTP02359 99.73  LDD2023 
Heme oxygenase 2 (HMOX2) LDTP03540 82.71  LDD2023 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 55.33  LDD2023 
Holocytochrome c-type synthase (HCCS) LDTP04581 41.07  LDD2023 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 99.73  LDD2023 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 35.26  LDD2023 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 57.68  LDD2023 
Lathosterol oxidase (SC5D) LDTP01329 28.44  LDD2023 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 28.05  LDD2023 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 31.56  LDD2023 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 25.28  LDD2023 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 32.45  LDD2023 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 48.17  LDD2023 
Lysosomal acid phosphatase (ACP2) LDTP02539 32.90  LDD2023 
Lysosomal alpha-glucosidase (GAA) LDTP02486 60.97  LDD2023 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 72.00  LDD2023 
Macrophage migration inhibitory factor (MIF) LDTP02713 32.45  LDD2023 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1) LDTP03677 27.47  LDD2023 
Methionine aminopeptidase 1 (METAP1) LDTP04565 48.50  LDD2023 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 47.18  LDD2023 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 26.35  LDD2023 
Minor histocompatibility antigen H13 (HM13) LDTP09396 66.72  LDD2023 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 38.05  LDD2023 
Mitofusin-1 (MFN1) LDTP08530 29.65  LDD2023 
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) LDTP00837 29.04  LDD2023 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 38.05  LDD2023 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 39.95  LDD2023 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 54.57  LDD2023 
NADH dehydrogenase 1 alpha subcomplex subunit 8 (NDUFA8) LDTP04494 26.35  LDD2023 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 30.70  LDD2023 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 99.73  LDD2023 
NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) LDTP01514 27.47  LDD2023 
NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial (NDUFB5) LDTP00831 39.67  LDD2023 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 91.14  LDD2023 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 27.28  LDD2023 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 95.67  LDD2023 
NADPH--cytochrome P450 reductase (POR) LDTP02848 25.46  LDD2023 
Oxidoreductase HTATIP2 (HTATIP2) LDTP11247 32.00  LDD2023 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 99.73  LDD2023 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 99.73  LDD2023 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 37.27  LDD2023 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 27.28  LDD2023 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 30.48  LDD2023 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 35.51  LDD2023 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 40.50  LDD2023 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 25.46  LDD2023 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 34.06  LDD2023 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 34.54  LDD2023 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 50.21  LDD2023 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 61.39  LDD2023 
Presequence protease, mitochondrial (PITRM1) LDTP07003 25.63  LDD2023 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 39.67  LDD2023 
Prostaglandin reductase 3 (PTGR3) LDTP15422 26.54  LDD2023 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 34.78  LDD2023 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 30.91  LDD2023 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 99.73  LDD2023 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 35.26  LDD2023 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 95.67  LDD2023 
Rab-like protein 3 (RABL3) LDTP06986 27.10  LDD2023 
Ras-related protein Rab-10 (RAB10) LDTP04895 37.01  LDD2023 
Ras-related protein Rab-1A (RAB1A) LDTP05006 26.17  LDD2023 
Ras-related protein Rab-1B (RAB1B) LDTP11733 61.82  LDD2023 
Ras-related protein Rab-2A (RAB2A) LDTP04892 27.47  LDD2023 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 45.57  LDD2023 
Retinol dehydrogenase 13 (RDH13) LDTP09061 37.01  LDD2023 
Ribitol 5-phosphate transferase FKRP (FKRP) LDTP12109 27.86  LDD2023 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 62.25  LDD2023 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 28.25  LDD2023 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 41.64  LDD2023 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 26.91  LDD2023 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 64.00  LDD2023 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 99.73  LDD2023 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 35.75  LDD2023 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 31.56  LDD2023 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 34.06  LDD2023 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 26.72  LDD2023 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 60.55  LDD2023 
Squalene monooxygenase (SQLE) LDTP06142 31.56  LDD2023 
Stearoyl-CoA desaturase (SCD) LDTP00344 38.05  LDD2023 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 27.47  LDD2023 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 56.10  LDD2023 
Thiol S-methyltransferase TMT1B (TMT1B) LDTP15155 27.67  LDD2023 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 33.82  LDD2023 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 29.04  LDD2023 
Torsin-1B (TOR1B) LDTP00400 42.81  LDD2023 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 45.57  LDD2023 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 27.10  LDD2023 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 25.81  LDD2023 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 40.22  LDD2023 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 46.85  LDD2023 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 49.18  LDD2023 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 74.54  LDD2023 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 40.79  LDD2023 
Xyloside xylosyltransferase 1 (XXYLT1) LDTP09053 27.86  LDD2023 
------------------------------------------------------------------------------------
⏷ Show the Full List of 164 Enzyme
144 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 49.87  LDD2023 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 84.45  LDD2023 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 44.02  LDD2023 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 62.25  LDD2023 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 33.36  LDD2023 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 25.81  LDD2023 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 29.04  LDD2023 
Apoptosis regulator BAX (BAX) LDTP05528 29.24  LDD2023 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 99.73  LDD2023 
ATP synthase subunit a (MT-ATP6) LDTP01804 99.73  LDD2023 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 34.06  LDD2023 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 99.73  LDD2023 
ATP-binding cassette sub-family F member 3 (ABCF3) LDTP16103 29.24  LDD2023 
Autophagy-related protein 9A (ATG9A) LDTP08030 39.95  LDD2023 
B-cell receptor-associated protein 29 (BCAP29) LDTP16201 34.78  LDD2023 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 53.82  LDD2023 
Bax inhibitor 1 (TMBIM6) LDTP04663 41.93  LDD2023 
BRI3-binding protein (BRI3BP) LDTP15648 99.73  LDD2023 
Calcium load-activated calcium channel (TMCO1) LDTP13599 27.47  LDD2023 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 26.72  LDD2023 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 28.84  LDD2023 
Calnexin (CANX) LDTP03405 26.35  LDD2023 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 38.05  LDD2023 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 74.54  LDD2023 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 80.45  LDD2023 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD2023 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 99.73  LDD2023 
Derlin-1 (DERL1) LDTP11245 99.73  LDD2023 
Derlin-2 (DERL2) LDTP11634 31.56  LDD2023 
Endophilin-B1 (SH3GLB1) LDTP13953 35.02  LDD2023 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 81.01  LDD2023 
Equilibrative nucleoside transporter 1 (SLC29A1) LDTP10985 27.47  LDD2023 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 71.01  LDD2023 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 99.73  LDD2023 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 99.73  LDD2023 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 91.77  LDD2023 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 99.73  LDD2023 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 74.03  LDD2023 
Integral membrane protein 2C (ITM2C) LDTP12451 48.17  LDD2023 
Integrin beta-1 (ITGB1) LDTP02122 27.47  LDD2023 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 25.28  LDD2023 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 76.64  LDD2023 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 97.01  LDD2023 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 99.73  LDD2023 
Lysosome membrane protein 2 (SCARB2) LDTP06034 49.18  LDD2023 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 99.73  LDD2023 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 99.73  LDD2023 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 99.73  LDD2023 
Metaxin-1 (MTX1) LDTP05900 85.04  LDD2023 
MICOS complex subunit MIC60 (IMMT) LDTP06660 37.27  LDD2023 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 44.63  LDD2023 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 51.98  LDD2023 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 48.17  LDD2023 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 48.84  LDD2023 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 65.34  LDD2023 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 99.73  LDD2023 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 99.73  LDD2023 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 83.87  LDD2023 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 97.68  LDD2023 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 99.73  LDD2023 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 77.71  LDD2023 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 37.53  LDD2023 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 95.01  LDD2023 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 70.03  LDD2023 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 76.11  LDD2023 
Mitochondrial pyruvate carrier 2 (MPC2) LDTP01631 28.64  LDD2023 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 41.36  LDD2023 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 55.33  LDD2023 
Mitoguardin 1 (MIGA1) LDTP09028 26.72  LDD2023 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 30.70  LDD2023 
Mpv17-like protein 2 (MPV17L2) LDTP14952 26.35  LDD2023 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 36.00  LDD2023 
Nuclear envelope pore membrane protein POM 121C (POM121C) LDTP00127 26.17  LDD2023 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 68.12  LDD2023 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 53.82  LDD2023 
Peroxisomal membrane protein 11A (PEX11A) LDTP01160 42.52  LDD2023 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 32.00  LDD2023 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 52.35  LDD2023 
PRA1 family protein 2 (PRAF2) LDTP01060 58.89  LDD2023 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 83.29  LDD2023 
Prosaposin (PSAP) LDTP02215 82.71  LDD2023 
Protein ERGIC-53 (LMAN1) LDTP04237 34.54  LDD2023 
Protein FAM8A1 (FAM8A1) LDTP16190 26.54  LDD2023 
Protein GPR107 (GPR107) LDTP07236 58.89  LDD2023 
Protein GPR108 (GPR108) LDTP12383 58.89  LDD2023 
Protein OS-9 (OS9) LDTP05871 30.48  LDD2023 
Protein RER1 (RER1) LDTP00590 30.70  LDD2023 
Protein RFT1 homolog (RFT1) LDTP10073 39.67  LDD2023 
Protein spinster homolog 1 (SPNS1) LDTP11844 69.07  LDD2023 
Protein tweety homolog 3 (TTYH3) LDTP11615 46.85  LDD2023 
Protein YIPF3 (YIPF3) LDTP11626 65.80  LDD2023 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 99.73  LDD2023 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 49.18  LDD2023 
Renin receptor (ATP6AP2) LDTP01309 49.18  LDD2023 
Reticulon-1 (RTN1) LDTP06633 39.95  LDD2023 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 67.18  LDD2023 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 27.67  LDD2023 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 49.52  LDD2023 
Sideroflexin-2 (SFXN2) LDTP10621 28.44  LDD2023 
Sideroflexin-4 (SFXN4) LDTP07531 42.52  LDD2023 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 28.25  LDD2023 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 30.70  LDD2023 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 40.22  LDD2023 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 99.73  LDD2023 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 29.04  LDD2023 
Sorting nexin-5 (SNX5) LDTP14174 34.54  LDD2023 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 42.81  LDD2023 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 55.33  LDD2023 
Stomatin (STOM) LDTP03380 40.22  LDD2023 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 66.72  LDD2023 
Syntaxin-6 (STX6) LDTP00857 83.29  LDD2023 
Tetraspanin-3 (TSPAN3) LDTP16813 99.73  LDD2023 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 29.45  LDD2023 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 88.03  LDD2023 
Translocation protein SEC62 (SEC62) LDTP15838 27.28  LDD2023 
Translocator protein (TSPO) LDTP03546 33.59  LDD2023 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD2023 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 37.27  LDD2023 
Transmembrane 9 superfamily member 4 (TM9SF4) LDTP09789 32.45  LDD2023 
Transmembrane emp24 domain-containing protein 1 (TMED1) LDTP05875 34.30  LDD2023 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 35.51  LDD2023 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 99.73  LDD2023 
Transmembrane protein 126A (TMEM126A) LDTP15948 99.73  LDD2023 
Transmembrane protein 14C (TMEM14C) LDTP12979 49.18  LDD2023 
Transmembrane protein 160 (TMEM160) LDTP20002 99.73  LDD2023 
Transmembrane protein 199 (TMEM199) LDTP08881 49.52  LDD2023 
Transmembrane protein 201 (TMEM201) LDTP07058 37.53  LDD2023 
Transmembrane protein 205 (TMEM205) LDTP07667 40.22  LDD2023 
Transmembrane protein 214 (TMEM214) LDTP07477 55.72  LDD2023 
Transmembrane protein 230 (TMEM230) LDTP10065 99.73  LDD2023 
Transmembrane protein 245 (TMEM245) LDTP15979 28.84  LDD2023 
Transmembrane protein 33 (TMEM33) LDTP04787 49.18  LDD2023 
Transmembrane protein 70, mitochondrial (TMEM70) LDTP11229 30.70  LDD2023 
Transmembrane protein 87A (TMEM87A) LDTP15481 41.64  LDD2023 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 26.72  LDD2023 
Trimeric intracellular cation channel type B (TMEM38B) LDTP12695 30.48  LDD2023 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 32.67  LDD2023 
Vacuole membrane protein 1 (VMP1) LDTP10343 28.84  LDD2023 
Vang-like protein 1 (VANGL1) LDTP09288 29.24  LDD2023 
Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B) LDTP13201 32.22  LDD2023 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 77.17  LDD2023 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 82.14  LDD2023 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 99.73  LDD2023 
Voltage-gated monoatomic cation channel TMEM109 (TMEM109) LDTP11281 31.12  LDD2023 
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⏷ Show the Full List of 144 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 59.71  LDD2023 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 36.76  LDD2023 
Leukocyte surface antigen CD47 (CD47) LDTP05572 83.29  LDD2023 
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148 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenomatous polyposis coli protein (APC) LDTP03303 26.72  LDD2023 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 76.64  LDD2023 
Alpha-internexin (INA) LDTP06527 29.24  LDD2023 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD2023 
Arfaptin-2 (ARFIP2) LDTP04557 39.40  LDD2023 
Armadillo repeat-containing protein 10 (ARMC10) LDTP08793 36.00  LDD2023 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 35.26  LDD2023 
Bombesin receptor-activated protein C6orf89 (C6orf89) LDTP07681 31.78  LDD2023 
BSD domain-containing protein 1 (BSDC1) LDTP16116 45.89  LDD2023 
C2 domain-containing protein 2 (C2CD2) LDTP18575 26.54  LDD2023 
Calmodulin-3 (CALM3) LDTP02443 27.47  LDD2023 
Centrin-2 (CETN2) LDTP03926 53.82  LDD2023 
Coiled-coil domain-containing protein 127 (CCDC127) LDTP20361 26.72  LDD2023 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 29.45  LDD2023 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 68.59  LDD2023 
COP9 signalosome complex subunit 8 (COPS8) LDTP10927 34.30  LDD2023 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD2023 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 59.30  LDD2023 
DENN domain-containing protein 11 (DENND11) LDTP16577 27.10  LDD2023 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 27.47  LDD2023 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 63.12  LDD2023 
Dynactin subunit 3 (DCTN3) LDTP01359 29.65  LDD2023 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 52.71  LDD2023 
Emerin (EMD) LDTP04356 49.87  LDD2023 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 52.71  LDD2023 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 35.51  LDD2023 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 82.71  LDD2023 
Endothelial differentiation-related factor 1 (EDF1) LDTP01067 27.47  LDD2023 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 56.10  LDD2023 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 44.63  LDD2023 
Ergosterol biosynthetic protein 28 homolog (ERG28) LDTP13478 26.54  LDD2023 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 25.63  LDD2023 
Formin-binding protein 1 (FNBP1) LDTP10786 82.71  LDD2023 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 60.97  LDD2023 
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) LDTP04871 26.72  LDD2023 
Ganglioside GM2 activator (GM2A) LDTP02927 67.18  LDD2023 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 36.25  LDD2023 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 30.70  LDD2023 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 61.82  LDD2023 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 45.89  LDD2023 
Golgin subfamily B member 1 (GOLGB1) LDTP06210 26.54  LDD2023 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 37.01  LDD2023 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 27.28  LDD2023 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 26.17  LDD2023 
HCLS1-associated protein X-1 (HAX1) LDTP00199 37.53  LDD2023 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 36.50  LDD2023 
Hyaluronan mediated motility receptor (HMMR) LDTP01177 25.81  LDD2023 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 45.57  LDD2023 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 88.65  LDD2023 
Integral membrane protein GPR180 (GPR180) LDTP19625 34.78  LDD2023 
Intron Large complex component GCFC2 (GCFC2) LDTP02841 38.32  LDD2023 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 55.33  LDD2023 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 66.26  LDD2023 
Kinesin light chain 4 (KLC4) LDTP12591 26.54  LDD2023 
Kinetochore protein Spc24 (SPC24) LDTP09069 25.28  LDD2023 
Kinetochore-associated protein 1 (KNTC1) LDTP04382 26.17  LDD2023 
Lamin-B1 (LMNB1) LDTP03065 27.47  LDD2023 
Lamin-B2 (LMNB2) LDTP05400 26.35  LDD2023 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 28.44  LDD2023 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 99.73  LDD2023 
Large proline-rich protein BAG6 (BAG6) LDTP04094 26.54  LDD2023 
Large ribosomal subunit protein mL45 (MRPL45) LDTP15863 25.28  LDD2023 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 28.05  LDD2023 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 28.44  LDD2023 
Leucine-rich repeat-containing protein 1 (LRRC1) LDTP15885 25.28  LDD2023 
LYR motif-containing protein 2 (LYRM2) LDTP18467 99.73  LDD2023 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 36.76  LDD2023 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 77.17  LDD2023 
MICOS complex subunit MIC27 (APOOL) LDTP07718 39.40  LDD2023 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 99.73  LDD2023 
Mitochondrial fission regulator 2 (MTFR2) LDTP15112 80.45  LDD2023 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 25.28  LDD2023 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 56.10  LDD2023 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 25.28  LDD2023 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2023 
Negative elongation factor C/D (NELFCD) LDTP08594 88.65  LDD2023 
Neurofilament light polypeptide (NEFL) LDTP02180 38.32  LDD2023 
Neurofilament medium polypeptide (NEFM) LDTP02181 35.02  LDD2023 
Nicastrin (NCSTN) LDTP09787 48.50  LDD2023 
Nucleobindin-1 (NUCB1) LDTP05375 27.28  LDD2023 
Nucleobindin-2 (NUCB2) LDTP05160 98.36  LDD2023 
Nurim (NRM) LDTP08606 66.26  LDD2023 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 79.89  LDD2023 
Optic atrophy 3 protein (OPA3) LDTP16006 99.73  LDD2023 
Oxysterol-binding protein-related protein 2 (OSBPL2) LDTP11774 27.47  LDD2023 
Perilipin-2 (PLIN2) LDTP10889 43.71  LDD2023 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 37.27  LDD2023 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 34.78  LDD2023 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 32.67  LDD2023 
Prefoldin subunit 6 (PFDN6) LDTP00573 30.70  LDD2023 
Prelamin-A/C (LMNA) LDTP01932 72.00  LDD2023 
Progesterone-induced-blocking factor 1 (PIBF1) LDTP09719 26.17  LDD2023 
Prohibitin-2 (PHB2) LDTP10924 51.27  LDD2023 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 25.63  LDD2023 
Protein FAM114A2 (FAM114A2) LDTP16080 65.80  LDD2023 
Protein FAM162A (FAM162A) LDTP10056 99.73  LDD2023 
Protein FAM177A1 (FAM177A1) LDTP15398 26.35  LDD2023 
Protein Hook homolog 2 (HOOK2) LDTP10255 31.78  LDD2023 
Protein jagunal homolog 1 (JAGN1) LDTP08904 54.57  LDD2023 
Protein LYRIC (MTDH) LDTP08224 67.18  LDD2023 
Protein PRRC1 (PRRC1) LDTP15778 36.76  LDD2023 
Protein Smaug homolog 2 (SAMD4B) LDTP07042 28.84  LDD2023 
Protein unc-119 homolog A (UNC119) LDTP05868 26.91  LDD2023 
Protein YIF1A (YIF1A) LDTP01494 61.39  LDD2023 
Protein YIF1B (YIF1B) LDTP06948 26.91  LDD2023 
Protein YIPF4 (YIPF4) LDTP11167 26.35  LDD2023 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 53.08  LDD2023 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 41.07  LDD2023 
Required for meiotic nuclear division protein 1 homolog (RMND1) LDTP12729 36.25  LDD2023 
Reticulocalbin-2 (RCN2) LDTP06097 27.10  LDD2023 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD2023 
Reticulon-4 (RTN4) LDTP12412 99.73  LDD2023 
Reticulophagy regulator 2 (RETREG2) LDTP09080 25.63  LDD2023 
Reticulophagy regulator 3 (RETREG3) LDTP08300 29.65  LDD2023 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 99.73  LDD2023 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 77.17  LDD2023 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 36.50  LDD2023 
Synaptogyrin-2 (SYNGR2) LDTP00859 41.64  LDD2023 
Synaptosomal-associated protein 29 (SNAP29) LDTP01661 26.17  LDD2023 
Syntaxin-10 (STX10) LDTP00986 99.73  LDD2023 
Syntaxin-12 (STX12) LDTP08389 26.54  LDD2023 
Syntaxin-18 (STX18) LDTP13086 99.73  LDD2023 
Syntaxin-7 (STX7) LDTP00632 37.27  LDD2023 
Testis-expressed protein 264 (TEX264) LDTP14259 47.84  LDD2023 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 33.13  LDD2023 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 62.68  LDD2023 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 99.73  LDD2023 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 27.28  LDD2023 
TraB domain-containing protein (TRABD) LDTP19963 99.73  LDD2023 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 35.26  LDD2023 
Transducin beta-like protein 2 (TBL2) LDTP16285 26.72  LDD2023 
Translocon-associated protein subunit delta (SSR4) LDTP04425 35.02  LDD2023 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 44.02  LDD2023 
Transmembrane protein 11, mitochondrial (TMEM11) LDTP02887 30.70  LDD2023 
Transmembrane protein 19 (TMEM19) LDTP10389 27.67  LDD2023 
Trophoblast glycoprotein (TPBG) LDTP05960 58.49  LDD2023 
Tropomyosin alpha-1 chain (TPM1) LDTP02351 27.10  LDD2023 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 26.72  LDD2023 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 46.53  LDD2023 
Tumor protein D52 (TPD52) LDTP04703 55.72  LDD2023 
Tumor protein D53 (TPD52L1) LDTP06659 26.91  LDD2023 
Tumor protein D54 (TPD52L2) LDTP00759 39.67  LDD2023 
Type-1 angiotensin II receptor-associated protein (AGTRAP) LDTP07632 29.86  LDD2023 
Ubiquilin-1 (UBQLN1) LDTP13626 28.05  LDD2023 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 95.67  LDD2023 
UBX domain-containing protein 4 (UBXN4) LDTP09806 27.28  LDD2023 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 58.08  LDD2023 
Vimentin (VIM) LDTP02297 63.56  LDD2023 
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⏷ Show the Full List of 148 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2023 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587