Details of the Target

General Information of Target

Target ID LDTP07058
Target Name Transmembrane protein 201 (TMEM201)
Gene Name TMEM201
Gene ID 199953
Synonyms
NET5; SAMP1; Transmembrane protein 201; Spindle-associated membrane protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEGVSALLARCPTAGLAGGLGVTACAAAGVLLYRIARRMKPTHTMVNCWFCNQDTLVPYG
NRNCWDCPHCEQYNGFQENGDYNKPIPAQYLEHLNHVVSSAPSLRDPSQPQQWVSSQVLL
CKRCNHHQTTKIKQLAAFAPREEGRYDEEVEVYRHHLEQMYKLCRPCQAAVEYYIKHQNR
QLRALLLSHQFKRREADQTHAQNFSSAVKSPVQVILLRALAFLACAFLLTTALYGASGHF
APGTTVPLALPPGGNGSATPDNGTTPGAEGWRQLLGLLPEHMAEKLCEAWAFGQSHQTGV
VALGLLTCLLAMLLAGRIRLRRIDAFCTCLWALLLGLHLAEQHLQAASPSWLDTLKFSTT
SLCCLVGFTAAVATRKATGPRRFRPRRFFPGDSAGLFPTSPSLAIPHPSVGGSPASLFIP
SPPSFLPLANQQLFRSPRRTSPSSLPGRLSRALSLGTIPSLTRADSGYLFSGSRPPSQVS
RSGEFPVSDYFSLLSGSCPSSPLPSPAPSVAGSVASSSGSLRHRRPLISPARLNLKGQKL
LLFPSPPGEAPTTPSSSDEHSPHNGSLFTMEPPHVPRKPPLQDVKHALDLRSKLERGSAC
SNRSIKKEDDSSQSSTCVVDTTTRGCSEEAATWRGRFGPSLVRGLLAVSLAANALFTSVF
LYQSLR
Target Bioclass
Transporter and channel
Family
TMEM201 family
Subcellular location
Nucleus inner membrane
Function
Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin-dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow. Overexpression can recruit Ran GTPase to the nuclear periphery.; [Isoform 2]: May define a distinct membrane domain in the vicinity of the mitotic spindle. Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina.
Uniprot ID
Q5SNT2
Ensemble ID
ENST00000340305.9
HGNC ID
HGNC:33719

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
22RV1 Deletion: p.P547LfsTer38 DBIA    Probe Info 
AN3CA SNV: p.A201T DBIA    Probe Info 
CAL120 SNV: p.M45T DBIA    Probe Info 
HT115 SNV: p.D392N .
IPC298 SNV: p.S557F DBIA    Probe Info 
JURKAT SNV: p.N179K Compound 10    Probe Info 
KP4 SNV: p.I132V DBIA    Probe Info 
RKO SNV: p.Q294Ter DBIA    Probe Info 
RPMI8226 SNV: p.C51Y .
SNGM SNV: p.P422L DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 18 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HDSF-alk
 Probe Info  		3.28  LDD0197  [1]
CHEMBL5175495
 Probe Info  		6.20  LDD0196  [2]
m-APA
 Probe Info  		13.27  LDD0403  [3]
BTD
 Probe Info  		C600(0.74)  LDD2109  [4]
AHL-Pu-1
 Probe Info  		C626(2.90)  LDD0171  [5]
HPAP
 Probe Info  		4.89  LDD0062  [6]
DBIA
 Probe Info  		C164(1.26); C167(1.26); C626(1.08)  LDD0078  [7]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [8]
Lodoacetamide azide
 Probe Info  		C124(0.00); C600(0.00)  LDD0037  [8]
DA-P3
 Probe Info  		N.A.  LDD0178  [9]
Compound 10
 Probe Info  		N.A.  LDD2216  [10]
ENE
 Probe Info  		N.A.  LDD0006  [11]
IPM
 Probe Info  		N.A.  LDD0005  [11]
STPyne
 Probe Info  		N.A.  LDD0009  [11]
TFBX
 Probe Info  		C124(0.00); C600(0.00)  LDD0148  [12]
VSF
 Probe Info  		N.A.  LDD0007  [11]
AOyne
 Probe Info  		15.00  LDD0443  [13]
NAIA_5
 Probe Info  		C124(0.00); C164(0.00)  LDD2223  [14]
PAL-AfBPP Probe
Click To Hide/Show 40 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C027
 Probe Info  		6.02  LDD1733  [15]
C040
 Probe Info  		8.51  LDD1740  [15]
C091
 Probe Info  		12.64  LDD1782  [15]
C092
 Probe Info  		19.97  LDD1783  [15]
C094
 Probe Info  		46.85  LDD1785  [15]
C100
 Probe Info  		5.06  LDD1789  [15]
C112
 Probe Info  		21.26  LDD1799  [15]
C134
 Probe Info  		23.92  LDD1816  [15]
C158
 Probe Info  		11.16  LDD1838  [15]
C161
 Probe Info  		14.52  LDD1841  [15]
C163
 Probe Info  		5.98  LDD1843  [15]
C165
 Probe Info  		13.45  LDD1845  [15]
C166
 Probe Info  		6.82  LDD1846  [15]
C169
 Probe Info  		21.56  LDD1849  [15]
C201
 Probe Info  		36.25  LDD1877  [15]
C206
 Probe Info  		16.34  LDD1881  [15]
C218
 Probe Info  		15.78  LDD1892  [15]
C220
 Probe Info  		16.91  LDD1894  [15]
C228
 Probe Info  		19.03  LDD1901  [15]
C231
 Probe Info  		16.56  LDD1904  [15]
C232
 Probe Info  		40.22  LDD1905  [15]
C234
 Probe Info  		5.62  LDD1907  [15]
C235
 Probe Info  		32.45  LDD1908  [15]
C246
 Probe Info  		15.14  LDD1919  [15]
C251
 Probe Info  		28.25  LDD1924  [15]
C252
 Probe Info  		9.19  LDD1925  [15]
C264
 Probe Info  		18.51  LDD1935  [15]
C266
 Probe Info  		8.17  LDD1937  [15]
C275
 Probe Info  		5.43  LDD1945  [15]
C285
 Probe Info  		22.32  LDD1955  [15]
C289
 Probe Info  		32.67  LDD1959  [15]
C339
 Probe Info  		5.50  LDD2002  [15]
C349
 Probe Info  		11.79  LDD2010  [15]
C350
 Probe Info  		27.47  LDD2011  [15]
C362
 Probe Info  		37.53  LDD2023  [15]
C388
 Probe Info  		62.25  LDD2047  [15]
C390
 Probe Info  		24.59  LDD2049  [15]
C403
 Probe Info  		16.68  LDD2061  [15]
C407
 Probe Info  		13.83  LDD2064  [15]
OEA-DA
 Probe Info  		5.41  LDD0046  [16]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C600(0.51)  LDD2117  [4]
 LDCM0026  4SU-RNA+native RNA DM93 C626(2.90)  LDD0171  [5]
 LDCM0561  Abegg_cp(-)-10 HeLa C124(2.58)  LDD0312  [12]
 LDCM0214  AC1 HCT 116 C11(0.93); C25(0.93); C121(1.20); C124(0.81)  LDD0531  [7]
 LDCM0215  AC10 HCT 116 C121(1.12); C164(1.03); C167(1.05); C626(1.19)  LDD0532  [7]
 LDCM0216  AC100 HCT 116 C11(0.58); C25(0.58); C121(0.98); C124(0.66)  LDD0533  [7]
 LDCM0217  AC101 HCT 116 C11(0.60); C25(0.60); C121(1.00); C124(0.80)  LDD0534  [7]
 LDCM0218  AC102 HCT 116 C11(0.60); C25(0.60); C121(1.01); C124(0.90)  LDD0535  [7]
 LDCM0219  AC103 HCT 116 C11(0.68); C25(0.68); C121(1.17); C124(1.05)  LDD0536  [7]
 LDCM0220  AC104 HCT 116 C11(0.63); C25(0.63); C121(1.07); C124(0.97)  LDD0537  [7]
 LDCM0221  AC105 HCT 116 C11(0.75); C25(0.75); C121(1.07); C124(0.90)  LDD0538  [7]
 LDCM0222  AC106 HCT 116 C11(0.56); C25(0.56); C121(1.08); C124(0.88)  LDD0539  [7]
 LDCM0223  AC107 HCT 116 C11(0.67); C25(0.78); C121(0.84); C124(0.58)  LDD0540  [7]
 LDCM0224  AC108 HCT 116 C11(0.70); C25(0.69); C121(0.92); C124(1.04)  LDD0541  [7]
 LDCM0225  AC109 HCT 116 C11(0.47); C25(0.54); C121(0.75); C124(1.26)  LDD0542  [7]
 LDCM0226  AC11 HCT 116 C121(1.10); C164(1.25); C167(1.24); C626(1.10)  LDD0543  [7]
 LDCM0227  AC110 HCT 116 C11(0.53); C25(0.55); C121(0.81); C124(1.19)  LDD0544  [7]
 LDCM0228  AC111 HCT 116 C11(0.69); C25(0.70); C121(0.80); C124(1.08)  LDD0545  [7]
 LDCM0229  AC112 HCT 116 C11(0.56); C25(0.54); C121(0.81); C124(0.90)  LDD0546  [7]
 LDCM0230  AC113 HCT 116 C11(1.01); C25(1.01); C121(0.97); C124(0.90)  LDD0547  [7]
 LDCM0231  AC114 HCT 116 C11(0.99); C25(0.99); C121(0.94); C124(0.97)  LDD0548  [7]
 LDCM0232  AC115 HCT 116 C11(0.95); C25(0.95); C121(1.01); C124(1.08)  LDD0549  [7]
 LDCM0233  AC116 HCT 116 C11(1.02); C25(1.02); C121(1.08); C124(1.31)  LDD0550  [7]
 LDCM0234  AC117 HCT 116 C11(1.01); C25(1.01); C121(1.07); C124(1.00)  LDD0551  [7]
 LDCM0235  AC118 HCT 116 C11(1.21); C25(1.21); C121(1.08); C124(1.02)  LDD0552  [7]
 LDCM0236  AC119 HCT 116 C11(1.09); C25(1.09); C121(1.05); C124(1.13)  LDD0553  [7]
 LDCM0237  AC12 HCT 116 C121(1.01); C164(0.98); C167(1.01); C626(1.35)  LDD0554  [7]
 LDCM0238  AC120 HCT 116 C11(0.91); C25(0.91); C121(1.10); C124(1.33)  LDD0555  [7]
 LDCM0239  AC121 HCT 116 C11(0.81); C25(0.81); C121(1.08); C124(1.06)  LDD0556  [7]
 LDCM0240  AC122 HCT 116 C11(0.91); C25(0.91); C121(0.96); C124(0.97)  LDD0557  [7]
 LDCM0241  AC123 HCT 116 C11(2.23); C25(2.23); C121(0.89); C124(0.94)  LDD0558  [7]
 LDCM0242  AC124 HCT 116 C11(1.37); C25(1.37); C121(1.03); C124(1.01)  LDD0559  [7]
 LDCM0243  AC125 HCT 116 C11(0.98); C25(0.98); C121(1.07); C124(0.96)  LDD0560  [7]
 LDCM0244  AC126 HCT 116 C11(1.27); C25(1.27); C121(1.18); C124(1.00)  LDD0561  [7]
 LDCM0245  AC127 HCT 116 C11(1.07); C25(1.07); C121(1.18); C124(1.12)  LDD0562  [7]
 LDCM0246  AC128 HCT 116 C121(1.35); C164(1.15); C167(1.15); C626(0.87)  LDD0563  [7]
 LDCM0247  AC129 HCT 116 C121(0.81); C164(0.89); C167(0.89); C626(1.01)  LDD0564  [7]
 LDCM0249  AC130 HCT 116 C121(1.08); C164(0.94); C167(0.94); C626(0.74)  LDD0566  [7]
 LDCM0250  AC131 HCT 116 C121(0.94); C164(1.15); C167(1.15); C626(0.83)  LDD0567  [7]
 LDCM0251  AC132 HCT 116 C121(0.78); C164(1.08); C167(1.08); C626(1.39)  LDD0568  [7]
 LDCM0252  AC133 HCT 116 C121(0.96); C164(1.00); C167(1.00); C626(0.91)  LDD0569  [7]
 LDCM0253  AC134 HCT 116 C121(0.96); C164(1.56); C167(1.56); C626(1.40)  LDD0570  [7]
 LDCM0254  AC135 HCT 116 C121(1.16); C164(1.24); C167(1.24); C626(0.90)  LDD0571  [7]
 LDCM0255  AC136 HCT 116 C121(1.05); C164(1.45); C167(1.45); C626(2.32)  LDD0572  [7]
 LDCM0256  AC137 HCT 116 C121(0.96); C164(1.51); C167(1.51); C626(1.03)  LDD0573  [7]
 LDCM0257  AC138 HCT 116 C121(0.98); C164(2.58); C167(2.58); C626(2.05)  LDD0574  [7]
 LDCM0258  AC139 HCT 116 C121(0.98); C164(1.80); C167(1.80); C626(2.45)  LDD0575  [7]
 LDCM0259  AC14 HCT 116 C121(1.10); C164(1.23); C167(1.17); C626(1.10)  LDD0576  [7]
 LDCM0260  AC140 HCT 116 C121(0.99); C164(2.06); C167(2.06); C626(1.62)  LDD0577  [7]
 LDCM0261  AC141 HCT 116 C121(0.94); C164(2.02); C167(2.02); C626(1.51)  LDD0578  [7]
 LDCM0262  AC142 HCT 116 C121(0.91); C164(1.54); C167(1.54); C626(1.08)  LDD0579  [7]
 LDCM0263  AC143 HCT 116 C121(1.11); C626(1.12); C164(1.29); C167(1.30)  LDD0580  [7]
 LDCM0264  AC144 HCT 116 C121(1.18); C626(1.39); C164(1.52); C167(1.53)  LDD0581  [7]
 LDCM0265  AC145 HCT 116 C626(1.10); C121(1.12); C164(1.21); C167(1.23)  LDD0582  [7]
 LDCM0266  AC146 HCT 116 C121(1.14); C164(1.38); C167(1.39); C626(1.43)  LDD0583  [7]
 LDCM0267  AC147 HCT 116 C121(1.23); C167(1.32); C164(1.33); C626(1.57)  LDD0584  [7]
 LDCM0268  AC148 HCT 116 C121(1.38); C164(1.48); C167(1.48); C626(2.01)  LDD0585  [7]
 LDCM0269  AC149 HCT 116 C121(1.21); C167(1.42); C164(1.42); C626(2.00)  LDD0586  [7]
 LDCM0270  AC15 HCT 116 C626(1.02); C121(1.08); C164(1.22); C167(1.22)  LDD0587  [7]
 LDCM0271  AC150 HCT 116 C121(1.03); C167(1.22); C164(1.23); C626(1.33)  LDD0588  [7]
 LDCM0272  AC151 HCT 116 C121(0.95); C626(1.17); C164(1.21); C167(1.22)  LDD0589  [7]
 LDCM0273  AC152 HCT 116 C121(1.24); C626(1.64); C167(2.19); C164(2.21)  LDD0590  [7]
 LDCM0274  AC153 HCT 116 C164(1.53); C167(1.56); C121(1.77); C626(2.01)  LDD0591  [7]
 LDCM0621  AC154 HCT 116 C121(1.26); C164(1.30); C167(1.33); C626(1.65)  LDD2158  [7]
 LDCM0622  AC155 HCT 116 C121(1.11); C164(1.22); C167(1.24); C626(1.48)  LDD2159  [7]
 LDCM0623  AC156 HCT 116 C121(1.05); C164(1.13); C167(1.13); C626(1.24)  LDD2160  [7]
 LDCM0624  AC157 HCT 116 C121(0.94); C164(0.99); C167(0.99); C626(1.17)  LDD2161  [7]
 LDCM0276  AC17 HCT 116 C167(0.90); C124(0.90); C164(0.92); C363(0.93)  LDD0593  [7]
 LDCM0277  AC18 HCT 116 C11(0.80); C25(0.80); C363(0.84); C364(0.84)  LDD0594  [7]
 LDCM0278  AC19 HCT 116 C124(0.85); C164(0.91); C167(0.93); C626(0.97)  LDD0595  [7]
 LDCM0279  AC2 HCT 116 C124(0.80); C164(0.82); C11(0.97); C25(0.97)  LDD0596  [7]
 LDCM0280  AC20 HCT 116 C124(0.92); C11(0.95); C25(0.95); C121(1.04)  LDD0597  [7]
 LDCM0281  AC21 HCT 116 C363(0.84); C364(0.84); C124(0.91); C11(0.98)  LDD0598  [7]
 LDCM0282  AC22 HCT 116 C124(0.89); C121(0.98); C164(0.99); C167(0.99)  LDD0599  [7]
 LDCM0283  AC23 HCT 116 C124(0.81); C626(0.85); C121(0.93); C167(1.01)  LDD0600  [7]
 LDCM0284  AC24 HCT 116 C124(0.83); C121(0.95); C363(0.97); C364(0.97)  LDD0601  [7]
 LDCM0285  AC25 HCT 116 C363(0.88); C364(0.88); C164(0.88); C167(0.90)  LDD0602  [7]
 LDCM0286  AC26 HCT 116 C11(0.82); C25(0.82); C363(0.82); C364(0.82)  LDD0603  [7]
 LDCM0287  AC27 HCT 116 C363(0.77); C364(0.77); C164(0.94); C167(0.95)  LDD0604  [7]
 LDCM0288  AC28 HCT 116 C363(0.73); C364(0.73); C164(0.86); C11(0.87)  LDD0605  [7]
 LDCM0289  AC29 HCT 116 C363(0.90); C364(0.90); C167(0.96); C164(0.96)  LDD0606  [7]
 LDCM0290  AC3 HCT 116 C124(0.75); C164(0.82); C626(0.96); C11(1.01)  LDD0607  [7]
 LDCM0291  AC30 HCT 116 C11(0.89); C25(0.89); C363(0.97); C364(0.97)  LDD0608  [7]
 LDCM0292  AC31 HCT 116 C363(0.71); C364(0.71); C11(0.85); C25(0.85)  LDD0609  [7]
 LDCM0293  AC32 HCT 116 C363(0.71); C364(0.71); C11(0.95); C25(0.95)  LDD0610  [7]
 LDCM0294  AC33 HCT 116 C363(0.86); C364(0.86); C626(1.03); C11(1.04)  LDD0611  [7]
 LDCM0295  AC34 HCT 116 C363(0.80); C364(0.80); C11(0.90); C25(0.90)  LDD0612  [7]
 LDCM0296  AC35 HCT 116 C363(0.76); C364(0.76); C11(0.91); C25(0.91)  LDD0613  [7]
 LDCM0297  AC36 HCT 116 C363(0.77); C364(0.77); C164(0.94); C626(0.99)  LDD0614  [7]
 LDCM0298  AC37 HCT 116 C363(0.79); C364(0.79); C164(0.91); C167(1.02)  LDD0615  [7]
 LDCM0299  AC38 HCT 116 C164(0.90); C363(0.98); C364(0.98); C121(0.99)  LDD0616  [7]
 LDCM0300  AC39 HCT 116 C363(0.81); C364(0.81); C164(0.91); C626(0.95)  LDD0617  [7]
 LDCM0301  AC4 HCT 116 C124(0.69); C11(0.92); C25(0.92); C626(0.99)  LDD0618  [7]
 LDCM0302  AC40 HCT 116 C363(1.04); C364(1.04); C626(1.08); C164(1.08)  LDD0619  [7]
 LDCM0303  AC41 HCT 116 C363(0.83); C364(0.83); C121(1.05); C11(1.05)  LDD0620  [7]
 LDCM0304  AC42 HCT 116 C363(0.96); C364(0.96); C121(0.99); C11(1.10)  LDD0621  [7]
 LDCM0305  AC43 HCT 116 C363(0.94); C364(0.94); C11(1.02); C25(1.02)  LDD0622  [7]
 LDCM0306  AC44 HCT 116 C363(0.95); C364(0.95); C626(1.05); C121(1.06)  LDD0623  [7]
 LDCM0307  AC45 HCT 116 C363(0.79); C364(0.79); C121(1.11); C11(1.12)  LDD0624  [7]
 LDCM0308  AC46 HCT 116 C124(0.84); C626(0.97); C11(1.07); C25(1.07)  LDD0625  [7]
 LDCM0309  AC47 HCT 116 C124(0.58); C626(0.94); C121(0.96); C11(0.98)  LDD0626  [7]
 LDCM0310  AC48 HCT 116 C124(0.80); C11(0.87); C25(0.87); C167(0.89)  LDD0627  [7]
 LDCM0311  AC49 HCT 116 C124(0.90); C626(1.08); C11(1.12); C25(1.12)  LDD0628  [7]
 LDCM0312  AC5 HCT 116 C124(0.72); C626(0.92); C164(0.96); C11(1.03)  LDD0629  [7]
 LDCM0313  AC50 HCT 116 C124(0.76); C11(1.01); C25(1.01); C626(1.11)  LDD0630  [7]
 LDCM0314  AC51 HCT 116 C124(0.76); C626(0.77); C121(0.89); C167(0.94)  LDD0631  [7]
 LDCM0315  AC52 HCT 116 C124(0.90); C626(0.94); C121(1.02); C11(1.04)  LDD0632  [7]
 LDCM0316  AC53 HCT 116 C124(0.56); C167(1.12); C626(1.13); C164(1.14)  LDD0633  [7]
 LDCM0317  AC54 HCT 116 C124(0.73); C11(1.10); C25(1.10); C626(1.19)  LDD0634  [7]
 LDCM0318  AC55 HCT 116 C124(0.58); C11(1.19); C25(1.19); C164(1.25)  LDD0635  [7]
 LDCM0319  AC56 HCT 116 C124(0.69); C121(1.32); C11(1.39); C25(1.39)  LDD0636  [7]
 LDCM0320  AC57 HCT 116 C11(0.96); C25(0.96); C164(1.04); C121(1.17)  LDD0637  [7]
 LDCM0321  AC58 HCT 116 C164(1.12); C167(1.16); C11(1.20); C25(1.20)  LDD0638  [7]
 LDCM0322  AC59 HCT 116 C167(1.14); C164(1.19); C11(1.25); C25(1.25)  LDD0639  [7]
 LDCM0323  AC6 HCT 116 C167(1.22); C121(1.26); C164(1.26); C626(1.52)  LDD0640  [7]
 LDCM0324  AC60 HCT 116 C11(0.94); C25(0.94); C167(1.21); C164(1.23)  LDD0641  [7]
 LDCM0325  AC61 HCT 116 C11(0.96); C25(0.96); C164(1.04); C167(1.06)  LDD0642  [7]
 LDCM0326  AC62 HCT 116 C121(1.36); C167(1.37); C164(1.51); C626(1.59)  LDD0643  [7]
 LDCM0327  AC63 HCT 116 C11(1.10); C25(1.10); C167(1.19); C164(1.26)  LDD0644  [7]
 LDCM0328  AC64 HCT 116 C167(1.18); C164(1.19); C121(1.35); C11(1.48)  LDD0645  [7]
 LDCM0329  AC65 HCT 116 C164(1.09); C167(1.11); C11(1.12); C25(1.12)  LDD0646  [7]
 LDCM0330  AC66 HCT 116 C11(1.03); C25(1.03); C167(1.10); C164(1.12)  LDD0647  [7]
 LDCM0331  AC67 HCT 116 C11(0.98); C25(0.98); C164(1.02); C167(1.13)  LDD0648  [7]
 LDCM0332  AC68 HCT 116 C121(1.01); C363(1.03); C364(1.03); C626(1.07)  LDD0649  [7]
 LDCM0333  AC69 HCT 116 C363(0.89); C364(0.89); C121(1.01); C626(1.19)  LDD0650  [7]
 LDCM0334  AC7 HCT 116 C121(1.10); C167(1.10); C164(1.12); C626(1.13)  LDD0651  [7]
 LDCM0335  AC70 HCT 116 C363(0.71); C364(0.71); C11(1.08); C25(1.08)  LDD0652  [7]
 LDCM0336  AC71 HCT 116 C363(0.75); C364(0.75); C121(0.93); C164(0.98)  LDD0653  [7]
 LDCM0337  AC72 HCT 116 C363(0.85); C364(0.85); C11(0.90); C25(0.90)  LDD0654  [7]
 LDCM0338  AC73 HCT 116 C11(1.46); C25(1.46); C363(0.98); C364(0.98)  LDD0655  [7]
 LDCM0339  AC74 HCT 116 C363(0.85); C364(0.85); C11(1.17); C25(1.17)  LDD0656  [7]
 LDCM0340  AC75 HCT 116 C363(1.23); C364(1.23); C121(1.35); C164(1.59)  LDD0657  [7]
 LDCM0341  AC76 HCT 116 C363(0.92); C364(0.92); C121(1.12); C164(1.16)  LDD0658  [7]
 LDCM0342  AC77 HCT 116 C363(1.03); C364(1.03); C121(1.07); C626(1.26)  LDD0659  [7]
 LDCM0343  AC78 HCT 116 C363(0.87); C364(0.87); C121(0.96); C164(1.08)  LDD0660  [7]
 LDCM0344  AC79 HCT 116 C363(0.75); C364(0.75); C121(1.00); C11(1.12)  LDD0661  [7]
 LDCM0345  AC8 HCT 116 C167(1.15); C164(1.17); C121(1.17); C626(1.30)  LDD0662  [7]
 LDCM0346  AC80 HCT 116 C363(0.88); C364(0.88); C11(1.13); C25(1.13)  LDD0663  [7]
 LDCM0347  AC81 HCT 116 C11(0.57); C25(0.57); C363(0.75); C364(0.75)  LDD0664  [7]
 LDCM0348  AC82 HCT 116 C363(1.10); C364(1.10); C121(1.19); C11(1.34)  LDD0665  [7]
 LDCM0349  AC83 HCT 116 C11(1.02); C25(1.02); C164(1.37); C626(1.39)  LDD0666  [7]
 LDCM0350  AC84 HCT 116 C11(0.97); C25(0.97); C626(1.29); C121(1.35)  LDD0667  [7]
 LDCM0351  AC85 HCT 116 C11(0.76); C25(0.76); C164(1.12); C167(1.17)  LDD0668  [7]
 LDCM0352  AC86 HCT 116 C11(0.88); C25(0.88); C164(0.98); C167(1.05)  LDD0669  [7]
 LDCM0353  AC87 HCT 116 C167(0.92); C164(0.92); C11(0.96); C25(0.96)  LDD0670  [7]
 LDCM0354  AC88 HCT 116 C11(0.87); C25(0.87); C164(0.98); C167(1.03)  LDD0671  [7]
 LDCM0355  AC89 HCT 116 C11(0.93); C25(0.93); C164(1.13); C121(1.20)  LDD0672  [7]
 LDCM0357  AC90 HCT 116 C164(0.78); C167(0.83); C121(0.95); C11(1.09)  LDD0674  [7]
 LDCM0358  AC91 HCT 116 C11(1.07); C25(1.07); C164(1.17); C167(1.29)  LDD0675  [7]
 LDCM0359  AC92 HCT 116 C11(1.10); C25(1.10); C164(1.16); C167(1.25)  LDD0676  [7]
 LDCM0360  AC93 HCT 116 C11(0.90); C25(0.90); C626(1.03); C167(1.03)  LDD0677  [7]
 LDCM0361  AC94 HCT 116 C11(0.88); C25(0.88); C164(1.01); C167(1.05)  LDD0678  [7]
 LDCM0362  AC95 HCT 116 C164(0.88); C121(0.99); C11(1.03); C25(1.03)  LDD0679  [7]
 LDCM0363  AC96 HCT 116 C11(0.96); C25(0.96); C164(0.97); C626(1.07)  LDD0680  [7]
 LDCM0364  AC97 HCT 116 C11(0.93); C25(0.93); C164(1.12); C167(1.21)  LDD0681  [7]
 LDCM0365  AC98 HCT 116 C11(0.58); C25(0.58); C164(1.00); C167(1.18)  LDD0682  [7]
 LDCM0366  AC99 HCT 116 C11(0.56); C25(0.56); C124(0.79); C626(0.85)  LDD0683  [7]
 LDCM0248  AKOS034007472 HCT 116 C121(0.98); C164(0.96); C167(0.95); C626(1.57)  LDD0565  [7]
 LDCM0356  AKOS034007680 HCT 116 C626(0.90); C167(1.04); C164(1.04); C121(1.09)  LDD0673  [7]
 LDCM0275  AKOS034007705 HCT 116 C164(1.40); C167(1.40); C626(1.43); C121(1.45)  LDD0592  [7]
 LDCM0156  Aniline NCI-H1299 13.27  LDD0403  [3]
 LDCM0020  ARS-1620 HCC44 C164(1.26); C167(1.26); C626(1.08)  LDD0078  [7]
 LDCM0632  CL-Sc Hep-G2 C124(0.26)  LDD2227  [14]
 LDCM0367  CL1 HCT 116 C363(0.77); C364(0.77); C121(0.95); C167(1.00)  LDD0684  [7]
 LDCM0368  CL10 HCT 116 C363(1.10); C364(1.10); C121(1.22); C167(1.29)  LDD0685  [7]
 LDCM0369  CL100 HCT 116 C124(0.59); C164(0.92); C626(0.93); C11(0.95)  LDD0686  [7]
 LDCM0370  CL101 HCT 116 C626(1.12); C121(1.12); C167(1.13); C164(1.22)  LDD0687  [7]
 LDCM0371  CL102 HCT 116 C121(0.95); C626(1.04); C167(1.13); C164(1.17)  LDD0688  [7]
 LDCM0372  CL103 HCT 116 C121(1.03); C167(1.07); C164(1.08); C626(1.16)  LDD0689  [7]
 LDCM0373  CL104 HCT 116 C121(0.96); C167(1.08); C626(1.14); C164(1.15)  LDD0690  [7]
 LDCM0374  CL105 HCT 116 C167(0.84); C164(0.86); C124(0.87); C363(0.93)  LDD0691  [7]
 LDCM0375  CL106 HCT 116 C164(0.82); C167(0.83); C124(0.89); C363(1.00)  LDD0692  [7]
 LDCM0376  CL107 HCT 116 C363(0.82); C364(0.82); C164(0.84); C167(0.88)  LDD0693  [7]
 LDCM0377  CL108 HCT 116 C626(0.83); C167(0.87); C164(0.92); C11(0.93)  LDD0694  [7]
 LDCM0378  CL109 HCT 116 C124(0.89); C164(0.93); C167(0.98); C363(0.99)  LDD0695  [7]
 LDCM0379  CL11 HCT 116 C363(1.09); C364(1.09); C167(1.27); C11(1.32)  LDD0696  [7]
 LDCM0380  CL110 HCT 116 C626(0.86); C164(0.87); C124(0.88); C363(0.88)  LDD0697  [7]
 LDCM0381  CL111 HCT 116 C124(0.87); C167(0.97); C164(1.06); C11(1.06)  LDD0698  [7]
 LDCM0382  CL112 HCT 116 C363(0.78); C364(0.78); C11(0.79); C25(0.79)  LDD0699  [7]
 LDCM0383  CL113 HCT 116 C11(0.84); C25(0.84); C363(0.85); C364(0.85)  LDD0700  [7]
 LDCM0384  CL114 HCT 116 C363(0.67); C364(0.67); C167(1.03); C124(1.04)  LDD0701  [7]
 LDCM0385  CL115 HCT 116 C363(0.93); C364(0.93); C11(0.97); C25(0.97)  LDD0702  [7]
 LDCM0386  CL116 HCT 116 C363(0.85); C364(0.85); C11(0.90); C25(0.90)  LDD0703  [7]
 LDCM0387  CL117 HCT 116 C363(0.97); C364(0.97); C164(1.15); C626(1.17)  LDD0704  [7]
 LDCM0388  CL118 HCT 116 C363(0.99); C364(0.99); C164(1.07); C121(1.15)  LDD0705  [7]
 LDCM0389  CL119 HCT 116 C363(0.74); C364(0.74); C626(1.00); C164(1.04)  LDD0706  [7]
 LDCM0390  CL12 HCT 116 C626(1.07); C11(1.19); C25(1.19); C167(1.27)  LDD0707  [7]
 LDCM0391  CL120 HCT 116 C363(0.67); C364(0.67); C626(0.95); C11(0.99)  LDD0708  [7]
 LDCM0392  CL121 HCT 116 C124(0.78); C121(1.30); C626(1.32); C167(1.37)  LDD0709  [7]
 LDCM0393  CL122 HCT 116 C124(0.97); C121(1.07); C626(1.10); C167(1.13)  LDD0710  [7]
 LDCM0394  CL123 HCT 116 C124(0.69); C167(1.12); C121(1.12); C164(1.19)  LDD0711  [7]
 LDCM0395  CL124 HCT 116 C124(0.70); C164(1.15); C167(1.16); C121(1.16)  LDD0712  [7]
 LDCM0396  CL125 HCT 116 C164(0.81); C167(0.93); C121(1.02); C11(1.02)  LDD0713  [7]
 LDCM0397  CL126 HCT 116 C121(1.10); C626(1.18); C167(1.22); C164(1.24)  LDD0714  [7]
 LDCM0398  CL127 HCT 116 C11(0.89); C25(0.89); C164(1.03); C121(1.15)  LDD0715  [7]
 LDCM0399  CL128 HCT 116 C11(0.99); C25(0.99); C164(1.00); C167(1.03)  LDD0716  [7]
 LDCM0400  CL13 HCT 116 C626(0.88); C363(0.99); C364(0.99); C11(1.08)  LDD0717  [7]
 LDCM0401  CL14 HCT 116 C167(0.97); C121(0.97); C626(1.01); C164(1.01)  LDD0718  [7]
 LDCM0402  CL15 HCT 116 C121(1.06); C363(1.30); C364(1.30); C164(1.34)  LDD0719  [7]
 LDCM0403  CL16 HCT 116 C121(0.97); C364(0.97); C626(0.98); C11(0.98)  LDD0720  [7]
 LDCM0404  CL17 HCT 116 C121(0.78); C364(0.87); C363(0.99); C164(1.08)  LDD0721  [7]
 LDCM0405  CL18 HCT 116 C364(0.72); C363(0.85); C11(0.88); C25(0.88)  LDD0722  [7]
 LDCM0406  CL19 HCT 116 C11(0.90); C25(0.90); C364(1.02); C164(1.06)  LDD0723  [7]
 LDCM0407  CL2 HCT 116 C363(0.81); C364(0.81); C121(0.95); C11(1.01)  LDD0724  [7]
 LDCM0408  CL20 HCT 116 C121(0.95); C11(1.07); C25(1.07); C363(1.10)  LDD0725  [7]
 LDCM0409  CL21 HCT 116 C364(0.83); C363(0.98); C121(1.13); C167(1.34)  LDD0726  [7]
 LDCM0410  CL22 HCT 116 C121(1.36); C11(1.44); C25(1.44); C363(1.51)  LDD0727  [7]
 LDCM0411  CL23 HCT 116 C11(0.96); C25(0.96); C121(1.10); C626(1.22)  LDD0728  [7]
 LDCM0412  CL24 HCT 116 C11(1.05); C25(1.05); C121(1.23); C164(1.41)  LDD0729  [7]
 LDCM0413  CL25 HCT 116 C11(2.09); C25(2.09); C121(1.06); C164(1.22)  LDD0730  [7]
 LDCM0414  CL26 HCT 116 C11(1.06); C25(1.06); C121(0.96); C164(1.07)  LDD0731  [7]
 LDCM0415  CL27 HCT 116 C11(1.10); C25(1.10); C121(0.97); C164(0.91)  LDD0732  [7]
 LDCM0416  CL28 HCT 116 C11(1.13); C25(1.13); C121(1.17); C164(1.16)  LDD0733  [7]
 LDCM0417  CL29 HCT 116 C11(1.10); C25(1.10); C121(1.25); C164(1.16)  LDD0734  [7]
 LDCM0418  CL3 HCT 116 C11(1.15); C25(1.15); C121(0.93); C164(1.06)  LDD0735  [7]
 LDCM0419  CL30 HCT 116 C11(1.08); C25(1.08); C121(0.89); C164(1.07)  LDD0736  [7]
 LDCM0420  CL31 HCT 116 C11(0.92); C25(0.92); C121(1.05); C124(0.77)  LDD0737  [7]
 LDCM0421  CL32 HCT 116 C11(0.73); C25(0.73); C121(1.15); C124(0.82)  LDD0738  [7]
 LDCM0422  CL33 HCT 116 C11(3.74); C25(3.74); C121(1.08); C124(0.80)  LDD0739  [7]
 LDCM0423  CL34 HCT 116 C11(1.33); C25(1.33); C121(1.27); C124(2.68)  LDD0740  [7]
 LDCM0424  CL35 HCT 116 C11(1.07); C25(1.07); C121(1.32); C124(0.94)  LDD0741  [7]
 LDCM0425  CL36 HCT 116 C11(0.84); C25(0.84); C121(1.24); C124(0.81)  LDD0742  [7]
 LDCM0426  CL37 HCT 116 C11(0.97); C25(0.97); C121(1.30); C124(1.06)  LDD0743  [7]
 LDCM0428  CL39 HCT 116 C11(1.16); C25(1.16); C121(1.21); C124(0.78)  LDD0745  [7]
 LDCM0429  CL4 HCT 116 C11(1.68); C25(1.68); C121(0.97); C164(1.12)  LDD0746  [7]
 LDCM0430  CL40 HCT 116 C11(1.43); C25(1.43); C121(1.11); C124(0.97)  LDD0747  [7]
 LDCM0431  CL41 HCT 116 C11(0.69); C25(0.69); C121(1.13); C124(0.79)  LDD0748  [7]
 LDCM0432  CL42 HCT 116 C11(1.43); C25(1.43); C121(1.78); C124(0.91)  LDD0749  [7]
 LDCM0433  CL43 HCT 116 C11(0.82); C25(0.82); C121(1.38); C124(0.75)  LDD0750  [7]
 LDCM0434  CL44 HCT 116 C11(0.91); C25(0.91); C121(1.16); C124(0.75)  LDD0751  [7]
 LDCM0435  CL45 HCT 116 C11(0.87); C25(0.87); C121(1.38); C124(0.65)  LDD0752  [7]
 LDCM0436  CL46 HCT 116 C121(0.84); C164(0.71); C167(0.90); C626(0.85)  LDD0753  [7]
 LDCM0437  CL47 HCT 116 C121(0.86); C164(0.81); C167(0.93); C626(0.92)  LDD0754  [7]
 LDCM0438  CL48 HCT 116 C121(0.80); C164(0.79); C167(0.84); C626(0.90)  LDD0755  [7]
 LDCM0439  CL49 HCT 116 C121(0.90); C164(0.77); C167(0.92); C626(1.10)  LDD0756  [7]
 LDCM0440  CL5 HCT 116 C11(0.95); C25(0.95); C121(1.02); C164(1.00)  LDD0757  [7]
 LDCM0441  CL50 HCT 116 C121(0.82); C164(0.74); C167(0.85); C626(0.81)  LDD0758  [7]
 LDCM0442  CL51 HCT 116 C121(0.88); C164(0.67); C167(0.89); C626(0.98)  LDD0759  [7]
 LDCM0443  CL52 HCT 116 C121(0.85); C164(0.68); C167(0.82); C626(1.06)  LDD0760  [7]
 LDCM0444  CL53 HCT 116 C121(0.81); C164(0.97); C167(0.99); C626(1.06)  LDD0761  [7]
 LDCM0445  CL54 HCT 116 C121(0.80); C164(0.78); C167(0.85); C626(0.92)  LDD0762  [7]
 LDCM0446  CL55 HCT 116 C121(0.79); C164(0.84); C167(0.88); C626(0.94)  LDD0763  [7]
 LDCM0447  CL56 HCT 116 C121(0.85); C164(0.91); C167(0.94); C626(1.15)  LDD0764  [7]
 LDCM0448  CL57 HCT 116 C121(0.83); C164(0.86); C167(0.86); C626(0.76)  LDD0765  [7]
 LDCM0449  CL58 HCT 116 C121(0.86); C164(0.69); C167(0.92); C626(0.85)  LDD0766  [7]
 LDCM0450  CL59 HCT 116 C121(0.86); C164(0.86); C167(0.95); C626(1.10)  LDD0767  [7]
 LDCM0451  CL6 HCT 116 C11(1.80); C25(1.80); C121(1.05); C164(0.93)  LDD0768  [7]
 LDCM0452  CL60 HCT 116 C121(0.92); C164(0.91); C167(1.05); C626(0.92)  LDD0769  [7]
 LDCM0453  CL61 HCT 116 C11(0.88); C25(0.88); C121(1.05); C164(0.85)  LDD0770  [7]
 LDCM0454  CL62 HCT 116 C11(0.84); C25(0.84); C121(1.03); C164(1.04)  LDD0771  [7]
 LDCM0455  CL63 HCT 116 C11(1.45); C25(1.45); C121(0.96); C164(0.98)  LDD0772  [7]
 LDCM0456  CL64 HCT 116 C11(2.12); C25(2.12); C121(1.01); C164(1.16)  LDD0773  [7]
 LDCM0457  CL65 HCT 116 C11(1.70); C25(1.70); C121(0.96); C164(0.96)  LDD0774  [7]
 LDCM0458  CL66 HCT 116 C11(1.08); C25(1.08); C121(1.23); C164(1.23)  LDD0775  [7]
 LDCM0459  CL67 HCT 116 C11(0.67); C25(0.67); C121(1.10); C164(1.25)  LDD0776  [7]
 LDCM0460  CL68 HCT 116 C11(1.13); C25(1.13); C121(0.98); C164(1.12)  LDD0777  [7]
 LDCM0461  CL69 HCT 116 C11(1.50); C25(1.50); C121(0.97); C164(1.01)  LDD0778  [7]
 LDCM0462  CL7 HCT 116 C11(1.19); C25(1.19); C121(1.28); C164(1.10)  LDD0779  [7]
 LDCM0463  CL70 HCT 116 C11(0.88); C25(0.88); C121(1.04); C164(1.07)  LDD0780  [7]
 LDCM0464  CL71 HCT 116 C11(0.77); C25(0.77); C121(1.06); C164(1.06)  LDD0781  [7]
 LDCM0465  CL72 HCT 116 C11(0.69); C25(0.69); C121(1.04); C164(1.15)  LDD0782  [7]
 LDCM0466  CL73 HCT 116 C11(1.10); C25(1.10); C121(1.01); C164(1.13)  LDD0783  [7]
 LDCM0467  CL74 HCT 116 C11(1.10); C25(1.10); C121(0.95); C164(1.21)  LDD0784  [7]
 LDCM0469  CL76 HCT 116 C121(1.07); C164(1.23); C167(1.08); C626(1.39)  LDD0786  [7]
 LDCM0470  CL77 HCT 116 C121(0.95); C164(1.35); C167(1.22); C626(1.26)  LDD0787  [7]
 LDCM0471  CL78 HCT 116 C121(0.99); C164(1.17); C167(1.08); C626(1.73)  LDD0788  [7]
 LDCM0472  CL79 HCT 116 C121(1.14); C164(1.29); C167(1.22); C626(1.52)  LDD0789  [7]
 LDCM0473  CL8 HCT 116 C11(4.33); C25(4.33); C121(1.30); C164(1.59)  LDD0790  [7]
 LDCM0474  CL80 HCT 116 C121(1.02); C164(1.19); C167(1.21); C626(1.38)  LDD0791  [7]
 LDCM0475  CL81 HCT 116 C121(1.09); C164(1.06); C167(1.06); C626(1.30)  LDD0792  [7]
 LDCM0476  CL82 HCT 116 C121(1.39); C164(1.45); C167(1.43); C626(1.66)  LDD0793  [7]
 LDCM0477  CL83 HCT 116 C121(1.31); C164(1.29); C167(1.27); C626(1.86)  LDD0794  [7]
 LDCM0478  CL84 HCT 116 C121(1.40); C164(1.50); C167(1.43); C626(1.75)  LDD0795  [7]
 LDCM0479  CL85 HCT 116 C121(1.06); C164(1.16); C167(1.10); C626(1.47)  LDD0796  [7]
 LDCM0480  CL86 HCT 116 C121(1.00); C164(1.05); C167(0.99); C626(1.27)  LDD0797  [7]
 LDCM0481  CL87 HCT 116 C121(1.14); C164(1.07); C167(1.02); C626(1.50)  LDD0798  [7]
 LDCM0482  CL88 HCT 116 C121(1.24); C164(1.31); C167(1.22); C626(1.66)  LDD0799  [7]
 LDCM0483  CL89 HCT 116 C121(1.74); C164(1.85); C167(1.74); C626(2.43)  LDD0800  [7]
 LDCM0484  CL9 HCT 116 C11(1.25); C25(1.25); C121(1.12); C164(1.04)  LDD0801  [7]
 LDCM0485  CL90 HCT 116 C121(0.92); C164(0.99); C167(1.00); C626(1.61)  LDD0802  [7]
 LDCM0486  CL91 HCT 116 C11(1.05); C25(1.05); C121(1.16); C124(0.97)  LDD0803  [7]
 LDCM0487  CL92 HCT 116 C11(1.63); C25(1.63); C121(1.07); C124(1.22)  LDD0804  [7]
 LDCM0488  CL93 HCT 116 C11(2.02); C25(2.02); C121(1.08); C124(0.99)  LDD0805  [7]
 LDCM0489  CL94 HCT 116 C11(1.77); C25(1.77); C121(1.03); C124(0.98)  LDD0806  [7]
 LDCM0490  CL95 HCT 116 C11(1.20); C25(1.20); C121(1.15); C124(1.08)  LDD0807  [7]
 LDCM0491  CL96 HCT 116 C11(1.36); C25(1.36); C121(1.10); C124(1.21)  LDD0808  [7]
 LDCM0492  CL97 HCT 116 C11(1.21); C25(1.21); C121(1.20); C124(0.91)  LDD0809  [7]
 LDCM0493  CL98 HCT 116 C11(1.08); C25(1.08); C121(1.23); C124(0.79)  LDD0810  [7]
 LDCM0494  CL99 HCT 116 C11(1.08); C25(1.08); C121(1.18); C124(0.93)  LDD0811  [7]
 LDCM0495  E2913 HEK-293T C600(1.07); C498(1.37); C167(1.05); C121(0.96)  LDD1698  [17]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C167(2.73)  LDD1702  [4]
 LDCM0625  F8 Ramos C600(1.70)  LDD2187  [18]
 LDCM0576  Fragment14 Ramos C600(0.73)  LDD2193  [18]
 LDCM0586  Fragment28 Ramos C600(0.87)  LDD2198  [18]
 LDCM0468  Fragment33 HCT 116 C11(1.18); C25(1.18); C121(0.99); C164(1.05)  LDD0785  [7]
 LDCM0427  Fragment51 HCT 116 C11(0.84); C25(0.84); C121(1.63); C124(0.91)  LDD0744  [7]
 LDCM0022  KB02 HCT 116 C121(2.46)  LDD0080  [7]
 LDCM0023  KB03 HCT 116 C121(3.18)  LDD0081  [7]
 LDCM0024  KB05 HCT 116 C121(2.30)  LDD0082  [7]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C600(0.74)  LDD2109  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C626(0.33)  LDD2206  [19]
 LDCM0014  Panhematin HEK-293T 4.89  LDD0062  [6]
 LDCM0021  THZ1 HCT 116 C626(1.11); C600(1.03); C164(1.04); C167(1.04)  LDD2173  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
NADH-cytochrome b5 reductase 3 (CYB5R3) Flavoprotein pyridine nucleotide cytochrome reductase family P00387
Tyrosine-protein phosphatase non-receptor type 5 (PTPN5) Protein-tyrosine phosphatase family P54829
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Novel acetylcholine receptor chaperone (TMEM35A) DoxX family Q53FP2
G protein-activated inward rectifier potassium channel 3 (KCNJ9) Inward rectifier-type potassium channel family Q92806
LHFPL tetraspan subfamily member 5 protein (LHFPL5) LHFP family Q8TAF8
Thioredoxin-related transmembrane protein 2 (TMX2) . Q9Y320
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
DnaJ homolog subfamily C member 1 (DNAJC1) . Q96KC8
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable G-protein coupled receptor 152 (GPR152) G-protein coupled receptor 1 family Q8TDT2
Other
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2) Complex I NDUFA12 subunit family Q8N183
Complexin-4 (CPLX4) Complexin/synaphin family Q7Z7G2
Major intrinsically disordered Notch2-binding receptor 1 (MINAR1) MINAR family Q9UPX6
C-type lectin domain family 17, member A (CLEC17A) . Q6ZS10
Emerin (EMD) . P50402
FERM domain-containing protein 3 (FRMD3) . A2A2Y4
Fetal and adult testis-expressed transcript protein (FATE1) . Q969F0
Leucine-rich repeat-containing protein 25 (LRRC25) . Q8N386

References

1 Fatty Acyl Sulfonyl Fluoride as an Activity-Based Probe for Profiling Fatty Acid-Associated Proteins in Living Cells. Chembiochem. 2022 Feb 16;23(4):e202100628. doi: 10.1002/cbic.202100628. Epub 2021 Dec 30.
2 Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.
3 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
7 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
8 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
9 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
10 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
11 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
12 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
13 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
14 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
15 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
16 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570
17 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
18 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
19 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.