Details of the Probe

General Information of Probe

Probe ID
LDPC0349
Probe Name
C100
Synonyms
Z4286591451
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 341.33
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C15H18F3N5O
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-4-propan-2-yl-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide
Canonical SMILES
CC(C)C1=C(NN=C1C(=O)NCCC2(N=N2)CCC#C)C(F)(F)F
InChI
InChI=1S/C15H18F3N5O/c1-4-5-6-14(22-23-14)7-8-19-13(24)11-10(9(2)3)12(21-20-11)15(16,17)18/h1,9H,5-8H2,2-3H3,(H,19,24)(H,20,21)
InChIKey
WCIJAFAMHSTZMG-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

122 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) LDTP09542 5.35  LDD1789 
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) LDTP09542 5.35  LDD1789 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 6.06  LDD1789 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 6.06  LDD1789 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 5.39  LDD1789 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 5.39  LDD1789 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 5.06  LDD1789 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 5.06  LDD1789 
ADP-dependent glucokinase (ADPGK) LDTP11127 5.46  LDD1789 
ADP-dependent glucokinase (ADPGK) LDTP11127 5.46  LDD1789 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 6.45  LDD1789 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 6.45  LDD1789 
Antigen peptide transporter 2 (TAP2) LDTP05409 6.11  LDD1789 
Antigen peptide transporter 2 (TAP2) LDTP05409 6.11  LDD1789 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 5.54  LDD1789 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 5.54  LDD1789 
Atlastin-2 (ATL2) LDTP09251 6.45  LDD1789 
Atlastin-2 (ATL2) LDTP09251 6.45  LDD1789 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 8.82  LDD1789 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 8.82  LDD1789 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 5.82  LDD1789 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 5.82  LDD1789 
Ceramide glucosyltransferase (UGCG) LDTP06617 5.43  LDD1789 
Ceramide glucosyltransferase (UGCG) LDTP06617 5.43  LDD1789 
Ceramide synthase 2 (CERS2) LDTP10329 5.78  LDD1789 
Ceramide synthase 2 (CERS2) LDTP10329 5.78  LDD1789 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 5.28  LDD1789 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 5.28  LDD1789 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 10.70  LDD1789 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 10.70  LDD1789 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 13.09  LDD1789 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 13.09  LDD1789 
Cytochrome b5 type B (CYB5B) LDTP00697 27.28  LDD1789 
Cytochrome b5 type B (CYB5B) LDTP00697 27.28  LDD1789 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 6.06  LDD1789 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 6.06  LDD1789 
Delta(24)-sterol reductase (DHCR24) LDTP06375 7.01  LDD1789 
Delta(24)-sterol reductase (DHCR24) LDTP06375 7.01  LDD1789 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 7.41  LDD1789 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 7.41  LDD1789 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 5.17  LDD1789 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 5.17  LDD1789 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 5.24  LDD1789 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 5.24  LDD1789 
Enolase-phosphatase E1 (ENOPH1) LDTP13314 6.28  LDD1789 
Enolase-phosphatase E1 (ENOPH1) LDTP13314 6.28  LDD1789 
Epoxide hydrolase 1 (EPHX1) LDTP02175 5.28  LDD1789 
Epoxide hydrolase 1 (EPHX1) LDTP02175 5.28  LDD1789 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 7.78  LDD1789 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 7.78  LDD1789 
GTP-binding protein Rheb (RHEB) LDTP06371 5.17  LDD1789 
GTP-binding protein Rheb (RHEB) LDTP06371 5.17  LDD1789 
Heme A synthase COX15 (COX15) LDTP07931 5.90  LDD1789 
Heme A synthase COX15 (COX15) LDTP07931 5.90  LDD1789 
Heme oxygenase 1 (HMOX1) LDTP02359 14.03  LDD1789 
Heme oxygenase 1 (HMOX1) LDTP02359 14.03  LDD1789 
Heme oxygenase 2 (HMOX2) LDTP03540 14.93  LDD1789 
Heme oxygenase 2 (HMOX2) LDTP03540 14.93  LDD1789 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 6.06  LDD1789 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 6.06  LDD1789 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.52  LDD1789 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.52  LDD1789 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 5.17  LDD1789 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 5.17  LDD1789 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 9.92  LDD1789 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 9.92  LDD1789 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 5.35  LDD1789 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 5.35  LDD1789 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 6.23  LDD1789 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 6.23  LDD1789 
Minor histocompatibility antigen H13 (HM13) LDTP09396 10.85  LDD1789 
Minor histocompatibility antigen H13 (HM13) LDTP09396 10.85  LDD1789 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 10.93  LDD1789 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 10.93  LDD1789 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 6.63  LDD1789 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 6.63  LDD1789 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 18.51  LDD1789 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 18.51  LDD1789 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 10.20  LDD1789 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 10.20  LDD1789 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 6.68  LDD1789 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 6.68  LDD1789 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 9.13  LDD1789 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 9.13  LDD1789 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 13.45  LDD1789 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 13.45  LDD1789 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 5.13  LDD1789 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 5.13  LDD1789 
Prostaglandin reductase 3 (PTGR3) LDTP15422 11.96  LDD1789 
Prostaglandin reductase 3 (PTGR3) LDTP15422 11.96  LDD1789 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 8.40  LDD1789 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 8.40  LDD1789 
Ras-related protein Rab-24 (RAB24) LDTP10020 6.92  LDD1789 
Ras-related protein Rab-24 (RAB24) LDTP10020 6.92  LDD1789 
Retinol dehydrogenase 13 (RDH13) LDTP09061 7.36  LDD1789 
Retinol dehydrogenase 13 (RDH13) LDTP09061 7.36  LDD1789 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 7.26  LDD1789 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 7.26  LDD1789 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 5.62  LDD1789 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 5.62  LDD1789 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 10.06  LDD1789 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 10.06  LDD1789 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 7.11  LDD1789 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 7.11  LDD1789 
Squalene monooxygenase (SQLE) LDTP06142 6.92  LDD1789 
Squalene monooxygenase (SQLE) LDTP06142 6.92  LDD1789 
Squalene synthase (FDFT1) LDTP03842 6.68  LDD1789 
Squalene synthase (FDFT1) LDTP03842 6.68  LDD1789 
TLC domain-containing protein 1 (TLCD1) LDTP10182 11.00  LDD1789 
TLC domain-containing protein 1 (TLCD1) LDTP10182 11.00  LDD1789 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 5.74  LDD1789 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 5.74  LDD1789 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 5.58  LDD1789 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 5.58  LDD1789 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 5.54  LDD1789 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 5.54  LDD1789 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 5.58  LDD1789 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 5.58  LDD1789 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 5.46  LDD1789 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 5.46  LDD1789 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 12.30  LDD1789 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 12.30  LDD1789 
------------------------------------------------------------------------------------
⏷ Show the Full List of 122 Enzyme
104 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Aladin (AAAS) LDTP12510 5.54  LDD1789 
Aladin (AAAS) LDTP12510 5.54  LDD1789 
Anoctamin-6 (ANO6) LDTP06855 5.21  LDD1789 
Anoctamin-6 (ANO6) LDTP06855 5.21  LDD1789 
BOS complex subunit NCLN (NCLN) LDTP10036 12.04  LDD1789 
BOS complex subunit NCLN (NCLN) LDTP10036 12.04  LDD1789 
BRI3-binding protein (BRI3BP) LDTP15648 22.78  LDD1789 
BRI3-binding protein (BRI3BP) LDTP15648 22.78  LDD1789 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 9.25  LDD1789 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 9.25  LDD1789 
Cytochrome c oxidase assembly protein COX20, mitochondrial (COX20) LDTP07053 8.57  LDD1789 
Cytochrome c oxidase assembly protein COX20, mitochondrial (COX20) LDTP07053 8.57  LDD1789 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 6.19  LDD1789 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 6.19  LDD1789 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 19.03  LDD1789 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 19.03  LDD1789 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 10.06  LDD1789 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 10.06  LDD1789 
Derlin-1 (DERL1) LDTP11245 4.96  LDD1789 
Derlin-1 (DERL1) LDTP11245 4.96  LDD1789 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 5.46  LDD1789 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 5.46  LDD1789 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 13.09  LDD1789 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 13.09  LDD1789 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 21.56  LDD1789 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 21.56  LDD1789 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 11.31  LDD1789 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 11.31  LDD1789 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 6.15  LDD1789 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 6.15  LDD1789 
Importin-4 (IPO4) LDTP09515 5.28  LDD1789 
Importin-4 (IPO4) LDTP09515 5.28  LDD1789 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 7.26  LDD1789 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 7.26  LDD1789 
Lysosome membrane protein 2 (SCARB2) LDTP06034 5.86  LDD1789 
Lysosome membrane protein 2 (SCARB2) LDTP06034 5.86  LDD1789 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 8.94  LDD1789 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 8.94  LDD1789 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 7.06  LDD1789 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 7.06  LDD1789 
Metaxin-1 (MTX1) LDTP05900 8.88  LDD1789 
Metaxin-1 (MTX1) LDTP05900 8.88  LDD1789 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 11.08  LDD1789 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 11.08  LDD1789 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 7.16  LDD1789 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 7.16  LDD1789 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 17.63  LDD1789 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 17.63  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 25.81  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 25.81  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 34.78  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 34.78  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 13.18  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 13.18  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 5.54  LDD1789 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 5.54  LDD1789 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 8.00  LDD1789 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 8.00  LDD1789 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 5.46  LDD1789 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 5.46  LDD1789 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 8.46  LDD1789 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 8.46  LDD1789 
Mpv17-like protein 2 (MPV17L2) LDTP14952 5.70  LDD1789 
Mpv17-like protein 2 (MPV17L2) LDTP14952 5.70  LDD1789 
Nucleoporin Nup37 (NUP37) LDTP09203 5.21  LDD1789 
Nucleoporin Nup37 (NUP37) LDTP09203 5.21  LDD1789 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 5.39  LDD1789 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 5.39  LDD1789 
Prosaposin (PSAP) LDTP02215 8.06  LDD1789 
Prosaposin (PSAP) LDTP02215 8.06  LDD1789 
Protein tweety homolog 3 (TTYH3) LDTP11615 6.54  LDD1789 
Protein tweety homolog 3 (TTYH3) LDTP11615 6.54  LDD1789 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 6.54  LDD1789 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 6.54  LDD1789 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 8.46  LDD1789 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 8.46  LDD1789 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 14.93  LDD1789 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 14.93  LDD1789 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 7.16  LDD1789 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 7.16  LDD1789 
Tetraspanin-3 (TSPAN3) LDTP16813 9.32  LDD1789 
Tetraspanin-3 (TSPAN3) LDTP16813 9.32  LDD1789 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 19.84  LDD1789 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 19.84  LDD1789 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 9.19  LDD1789 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 9.19  LDD1789 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 6.11  LDD1789 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 6.11  LDD1789 
Transmembrane protein 126A (TMEM126A) LDTP15948 7.78  LDD1789 
Transmembrane protein 126A (TMEM126A) LDTP15948 7.78  LDD1789 
Transmembrane protein 160 (TMEM160) LDTP20002 16.11  LDD1789 
Transmembrane protein 160 (TMEM160) LDTP20002 16.11  LDD1789 
Transmembrane protein 201 (TMEM201) LDTP07058 5.06  LDD1789 
Transmembrane protein 201 (TMEM201) LDTP07058 5.06  LDD1789 
Transmembrane protein 230 (TMEM230) LDTP10065 5.70  LDD1789 
Transmembrane protein 230 (TMEM230) LDTP10065 5.70  LDD1789 
Transmembrane protein 65 (TMEM65) LDTP07583 6.82  LDD1789 
Transmembrane protein 65 (TMEM65) LDTP07583 6.82  LDD1789 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 9.32  LDD1789 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 9.32  LDD1789 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 7.94  LDD1789 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 7.94  LDD1789 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 4.99  LDD1789 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 4.99  LDD1789 
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⏷ Show the Full List of 104 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 5.31  LDD1789 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 5.31  LDD1789 
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78 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 5.58  LDD1789 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 5.58  LDD1789 
Apolipoprotein L2 (APOL2) LDTP11076 12.55  LDD1789 
Apolipoprotein L2 (APOL2) LDTP11076 12.55  LDD1789 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 6.06  LDD1789 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 6.06  LDD1789 
Centromere protein K (CENPK) LDTP11143 5.70  LDD1789 
Centromere protein K (CENPK) LDTP11143 5.70  LDD1789 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 7.57  LDD1789 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 7.57  LDD1789 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 6.77  LDD1789 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 6.77  LDD1789 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 10.06  LDD1789 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 10.06  LDD1789 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 13.09  LDD1789 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 13.09  LDD1789 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 5.50  LDD1789 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 5.50  LDD1789 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 5.50  LDD1789 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 5.50  LDD1789 
Integral membrane protein GPR180 (GPR180) LDTP19625 5.70  LDD1789 
Integral membrane protein GPR180 (GPR180) LDTP19625 5.70  LDD1789 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 9.99  LDD1789 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 9.99  LDD1789 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 4.96  LDD1789 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 4.96  LDD1789 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 5.10  LDD1789 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 5.10  LDD1789 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 13.83  LDD1789 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 13.83  LDD1789 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 28.44  LDD1789 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 28.44  LDD1789 
Nucleobindin-1 (NUCB1) LDTP05375 7.16  LDD1789 
Nucleobindin-1 (NUCB1) LDTP05375 7.16  LDD1789 
Nucleobindin-2 (NUCB2) LDTP05160 16.45  LDD1789 
Nucleobindin-2 (NUCB2) LDTP05160 16.45  LDD1789 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 7.89  LDD1789 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 7.89  LDD1789 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 14.83  LDD1789 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 14.83  LDD1789 
Polyamine-modulated factor 1 (PMF1) LDTP07508 4.99  LDD1789 
Polyamine-modulated factor 1 (PMF1) LDTP07508 4.99  LDD1789 
Protein FAM114A2 (FAM114A2) LDTP16080 6.54  LDD1789 
Protein FAM114A2 (FAM114A2) LDTP16080 6.54  LDD1789 
Protein FAM162A (FAM162A) LDTP10056 13.93  LDD1789 
Protein FAM162A (FAM162A) LDTP10056 13.93  LDD1789 
Protein FAM177A1 (FAM177A1) LDTP15398 9.25  LDD1789 
Protein FAM177A1 (FAM177A1) LDTP15398 9.25  LDD1789 
Protein jagunal homolog 1 (JAGN1) LDTP08904 5.35  LDD1789 
Protein jagunal homolog 1 (JAGN1) LDTP08904 5.35  LDD1789 
Protein S100-A13 (S100A13) LDTP10908 7.46  LDD1789 
Protein S100-A13 (S100A13) LDTP10908 7.46  LDD1789 
Protein YIF1A (YIF1A) LDTP01494 9.19  LDD1789 
Protein YIF1A (YIF1A) LDTP01494 9.19  LDD1789 
Reticulocalbin-2 (RCN2) LDTP06097 5.66  LDD1789 
Reticulocalbin-2 (RCN2) LDTP06097 5.66  LDD1789 
Reticulon-2 (RTN2) LDTP01167 8.06  LDD1789 
Reticulon-2 (RTN2) LDTP01167 8.06  LDD1789 
Reticulon-3 (RTN3) LDTP01522 15.56  LDD1789 
Reticulon-3 (RTN3) LDTP01522 15.56  LDD1789 
Reticulon-4 (RTN4) LDTP12412 12.21  LDD1789 
Reticulon-4 (RTN4) LDTP12412 12.21  LDD1789 
RNA-binding protein 39 (RBM39) LDTP06128 5.28  LDD1789 
RNA-binding protein 39 (RBM39) LDTP06128 5.28  LDD1789 
RUS family member 1 (RUSF1) LDTP10357 5.10  LDD1789 
RUS family member 1 (RUSF1) LDTP10357 5.10  LDD1789 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 6.19  LDD1789 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 6.19  LDD1789 
Synaptogyrin-2 (SYNGR2) LDTP00859 9.13  LDD1789 
Synaptogyrin-2 (SYNGR2) LDTP00859 9.13  LDD1789 
Syntaxin-18 (STX18) LDTP13086 11.24  LDD1789 
Syntaxin-18 (STX18) LDTP13086 11.24  LDD1789 
Tetraspanin-6 (TSPAN6) LDTP14458 5.70  LDD1789 
Tetraspanin-6 (TSPAN6) LDTP14458 5.70  LDD1789 
TraB domain-containing protein (TRABD) LDTP19963 7.41  LDD1789 
TraB domain-containing protein (TRABD) LDTP19963 7.41  LDD1789 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 9.13  LDD1789 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 9.13  LDD1789 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1789 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587