Details of the Probe

General Information of Probe

Probe ID
LDPC0401
Probe Name
C161
Synonyms
Z4225932648
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 360.9
Lipid-water partition coefficient (xlogp) 3.8
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H17ClN4OS
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-3-(5-chloro-1,3-benzothiazol-2-yl)propanamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)CCC2=NC3=C(S2)C=CC(=C3)Cl
InChI
InChI=1S/C17H17ClN4OS/c1-2-3-8-17(21-22-17)9-10-19-15(23)6-7-16-20-13-11-12(18)4-5-14(13)24-16/h1,4-5,11H,3,6-10H2,(H,19,23)
InChIKey
GEQFMWHDSFNYLE-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

195 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 30.06  LDD1841 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 24.93  LDD1841 
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3) LDTP15132 11.47  LDD1841 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 32.90  LDD1841 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 14.03  LDD1841 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 11.24  LDD1841 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 10.93  LDD1841 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 16.56  LDD1841 
Acid ceramidase (ASAH1) LDTP05905 25.28  LDD1841 
Activin receptor type-1B (ACVR1B) LDTP03822 10.85  LDD1841 
Acyl-CoA 6-desaturase (FADS2) LDTP01699 10.48  LDD1841 
Acyl-CoA dehydrogenase family member 11 (ACAD11) LDTP07873 10.78  LDD1841 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 10.13  LDD1841 
Adenosine deaminase (ADA) LDTP01803 19.97  LDD1841 
ADP-dependent glucokinase (ADPGK) LDTP11127 23.26  LDD1841 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 23.59  LDD1841 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 19.84  LDD1841 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 11.88  LDD1841 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 24.59  LDD1841 
Alpha-galactosidase A (GLA) LDTP02141 12.30  LDD1841 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.91  LDD1841 
Antigen peptide transporter 1 (TAP1) LDTP05408 10.41  LDD1841 
Antigen peptide transporter 2 (TAP2) LDTP05409 15.35  LDD1841 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 14.22  LDD1841 
Atlastin-2 (ATL2) LDTP09251 11.47  LDD1841 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 11.88  LDD1841 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 13.18  LDD1841 
ATPase GET3 (GET3) LDTP00836 12.21  LDD1841 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 10.70  LDD1841 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 9.85  LDD1841 
Beta-galactosidase (GLB1) LDTP02837 20.25  LDD1841 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 10.06  LDD1841 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 27.28  LDD1841 
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) LDTP00462 13.64  LDD1841 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 37.53  LDD1841 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 23.59  LDD1841 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 37.53  LDD1841 
Catechol O-methyltransferase (COMT) LDTP03145 20.11  LDD1841 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 18.77  LDD1841 
Cell division cycle protein 23 homolog (CDC23) LDTP13408 19.56  LDD1841 
Ceramide glucosyltransferase (UGCG) LDTP06617 16.45  LDD1841 
Ceramide kinase (CERK) LDTP09391 21.56  LDD1841 
Ceramide synthase 1 (CERS1) LDTP03394 28.05  LDD1841 
Ceramide synthase 2 (CERS2) LDTP10329 25.46  LDD1841 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 14.12  LDD1841 
Choline kinase alpha (CHKA) LDTP03787 12.64  LDD1841 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 14.22  LDD1841 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 12.91  LDD1841 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 10.13  LDD1841 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 12.38  LDD1841 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 59.30  LDD1841 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 36.25  LDD1841 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1841 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 16.22  LDD1841 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 64.45  LDD1841 
DCN1-like protein 4 (DCUN1D4) LDTP09799 12.04  LDD1841 
DCN1-like protein 5 (DCUN1D5) LDTP11199 9.92  LDD1841 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 21.86  LDD1841 
Delta(24)-sterol reductase (DHCR24) LDTP06375 25.63  LDD1841 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 12.04  LDD1841 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 22.78  LDD1841 
Dihydrofolate reductase (DHFR) LDTP01769 21.11  LDD1841 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 19.56  LDD1841 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 20.25  LDD1841 
E3 ubiquitin-protein ligase NEDD4 (NEDD4) LDTP04114 16.11  LDD1841 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 15.03  LDD1841 
E3 ubiquitin-protein ligase RNF13 (RNF13) LDTP00804 19.84  LDD1841 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 9.78  LDD1841 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 10.20  LDD1841 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 14.83  LDD1841 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 11.79  LDD1841 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 13.55  LDD1841 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 12.04  LDD1841 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 27.67  LDD1841 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 24.59  LDD1841 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 19.56  LDD1841 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 10.13  LDD1841 
Ferrochelatase, mitochondrial (FECH) LDTP03198 11.47  LDD1841 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 24.25  LDD1841 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 13.09  LDD1841 
GTP-binding protein SAR1a (SAR1A) LDTP12470 9.85  LDD1841 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 10.78  LDD1841 
Heme oxygenase 1 (HMOX1) LDTP02359 26.72  LDD1841 
Heme oxygenase 2 (HMOX2) LDTP03540 53.82  LDD1841 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 14.03  LDD1841 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 11.55  LDD1841 
Histone-lysine N-methyltransferase SETD1A (SETD1A) LDTP00518 9.85  LDD1841 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 25.99  LDD1841 
Inositol polyphosphate-4-phosphatase type I A (INPP4A) LDTP10676 9.99  LDD1841 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 10.41  LDD1841 
Ketosamine-3-kinase (FN3KRP) LDTP16025 18.00  LDD1841 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 12.73  LDD1841 
Lathosterol oxidase (SC5D) LDTP01329 10.48  LDD1841 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 15.14  LDD1841 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 11.16  LDD1841 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 53.08  LDD1841 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 12.04  LDD1841 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 35.51  LDD1841 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 16.00  LDD1841 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 10.41  LDD1841 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 22.47  LDD1841 
Lysosomal acid phosphatase (ACP2) LDTP02539 12.55  LDD1841 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 24.08  LDD1841 
Lysosomal protective protein (CTSA) LDTP02505 31.34  LDD1841 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 32.45  LDD1841 
m7GpppX diphosphatase (DCPS) LDTP10163 11.31  LDD1841 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) LDTP00975 10.63  LDD1841 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 13.74  LDD1841 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 18.51  LDD1841 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 21.71  LDD1841 
Minor histocompatibility antigen H13 (HM13) LDTP09396 12.04  LDD1841 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 24.25  LDD1841 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 11.55  LDD1841 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 17.03  LDD1841 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 15.56  LDD1841 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 23.75  LDD1841 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 16.91  LDD1841 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 20.82  LDD1841 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 14.32  LDD1841 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 58.08  LDD1841 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 23.75  LDD1841 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 34.30  LDD1841 
Nardilysin (NRDC) LDTP00886 10.63  LDD1841 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 20.97  LDD1841 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 52.71  LDD1841 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 24.59  LDD1841 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 10.13  LDD1841 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 24.59  LDD1841 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 13.36  LDD1841 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 56.49  LDD1841 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 13.45  LDD1841 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 13.64  LDD1841 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 30.48  LDD1841 
Peroxisomal trans-2-enoyl-CoA reductase (PECR) LDTP11437 13.27  LDD1841 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 9.99  LDD1841 
Phospholipase A2 group XV (PLA2G15) LDTP09088 15.14  LDD1841 
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (PHKA1) LDTP04080 9.78  LDD1841 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 11.79  LDD1841 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 31.34  LDD1841 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 28.25  LDD1841 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 15.56  LDD1841 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 9.85  LDD1841 
Prolyl endopeptidase-like (PREPL) LDTP06849 13.83  LDD1841 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 12.91  LDD1841 
Prostaglandin reductase 3 (PTGR3) LDTP15422 16.22  LDD1841 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 26.72  LDD1841 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 17.15  LDD1841 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 17.03  LDD1841 
Protein arginine methyltransferase NDUFAF7, mitochondrial (NDUFAF7) LDTP07961 10.20  LDD1841 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 11.63  LDD1841 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 21.86  LDD1841 
Protein O-GlcNAcase (OGA) LDTP00988 11.00  LDD1841 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 12.91  LDD1841 
Protein phosphatase 1L (PPM1L) LDTP07057 10.70  LDD1841 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 12.55  LDD1841 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 30.70  LDD1841 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 25.28  LDD1841 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 22.16  LDD1841 
Rab-like protein 3 (RABL3) LDTP06986 12.82  LDD1841 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 10.27  LDD1841 
Ras-related protein Rab-24 (RAB24) LDTP10020 14.03  LDD1841 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 67.65  LDD1841 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 30.27  LDD1841 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 27.86  LDD1841 
Retinol dehydrogenase 13 (RDH13) LDTP09061 11.31  LDD1841 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 14.52  LDD1841 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 14.22  LDD1841 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 10.63  LDD1841 
Serine/threonine-protein kinase VRK2 (VRK2) LDTP08378 10.85  LDD1841 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 37.79  LDD1841 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 18.13  LDD1841 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 10.34  LDD1841 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 19.97  LDD1841 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 12.91  LDD1841 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 17.15  LDD1841 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 15.78  LDD1841 
Squalene synthase (FDFT1) LDTP03842 25.99  LDD1841 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 11.63  LDD1841 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 15.35  LDD1841 
Thiol S-methyltransferase TMT1B (TMT1B) LDTP15155 11.31  LDD1841 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 17.27  LDD1841 
Threonine--tRNA ligase, mitochondrial (TARS2) LDTP11319 11.71  LDD1841 
TLC domain-containing protein 1 (TLCD1) LDTP10182 20.68  LDD1841 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 16.11  LDD1841 
Triokinase/FMN cyclase (TKFC) LDTP06779 10.20  LDD1841 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 26.54  LDD1841 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 41.93  LDD1841 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 13.55  LDD1841 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 12.13  LDD1841 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 14.93  LDD1841 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 10.48  LDD1841 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 16.34  LDD1841 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 25.63  LDD1841 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 17.88  LDD1841 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 12.13  LDD1841 
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⏷ Show the Full List of 195 Enzyme
130 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 11.88  LDD1841 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 20.97  LDD1841 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 10.85  LDD1841 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 12.55  LDD1841 
Amyloid-beta precursor protein (APP) LDTP02071 18.38  LDD1841 
Anoctamin-10 (ANO10) LDTP12704 14.93  LDD1841 
Anoctamin-6 (ANO6) LDTP06855 10.48  LDD1841 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 17.75  LDD1841 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 39.40  LDD1841 
BRI3-binding protein (BRI3BP) LDTP15648 16.80  LDD1841 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 9.92  LDD1841 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 39.40  LDD1841 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 17.15  LDD1841 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD1841 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 11.71  LDD1841 
Derlin-1 (DERL1) LDTP11245 23.75  LDD1841 
Derlin-2 (DERL2) LDTP11634 11.16  LDD1841 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 12.82  LDD1841 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 11.16  LDD1841 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 69.07  LDD1841 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 67.18  LDD1841 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 17.39  LDD1841 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 11.71  LDD1841 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 15.03  LDD1841 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 17.75  LDD1841 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 18.13  LDD1841 
Importin subunit alpha-1 (KPNA2) LDTP04501 12.91  LDD1841 
Integral membrane protein 2B (ITM2B) LDTP13833 17.63  LDD1841 
Integral membrane protein 2C (ITM2C) LDTP12451 19.43  LDD1841 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 10.85  LDD1841 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 18.13  LDD1841 
Lysosome membrane protein 2 (SCARB2) LDTP06034 35.02  LDD1841 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 19.29  LDD1841 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 16.34  LDD1841 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 11.88  LDD1841 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 24.25  LDD1841 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 16.80  LDD1841 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 29.04  LDD1841 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 12.47  LDD1841 
Metal transporter CNNM3 (CNNM3) LDTP09144 10.34  LDD1841 
Metal transporter CNNM4 (CNNM4) LDTP07537 9.71  LDD1841 
Metaxin-1 (MTX1) LDTP05900 23.92  LDD1841 
Metaxin-2 (MTX2) LDTP01217 30.70  LDD1841 
MICOS complex subunit MIC26 (APOO) LDTP11250 12.38  LDD1841 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 27.86  LDD1841 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 10.06  LDD1841 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 11.63  LDD1841 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 14.52  LDD1841 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 13.83  LDD1841 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 35.02  LDD1841 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 29.65  LDD1841 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1841 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1841 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 18.13  LDD1841 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 10.85  LDD1841 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 24.42  LDD1841 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 16.00  LDD1841 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 11.47  LDD1841 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 64.45  LDD1841 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 13.18  LDD1841 
Mitoguardin 1 (MIGA1) LDTP09028 15.03  LDD1841 
Mpv17-like protein 2 (MPV17L2) LDTP14952 47.18  LDD1841 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 11.55  LDD1841 
Nucleoporin NDC1 (NDC1) LDTP11213 18.25  LDD1841 
Pannexin-1 (PANX1) LDTP10754 9.99  LDD1841 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 19.43  LDD1841 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 24.08  LDD1841 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 17.51  LDD1841 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 11.39  LDD1841 
Prosaposin (PSAP) LDTP02215 25.11  LDD1841 
Protein FAM8A1 (FAM8A1) LDTP16190 13.83  LDD1841 
Protein GPR107 (GPR107) LDTP07236 56.49  LDD1841 
Protein GPR108 (GPR108) LDTP12383 26.91  LDD1841 
Protein RER1 (RER1) LDTP00590 10.56  LDD1841 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 10.56  LDD1841 
Protein spinster homolog 1 (SPNS1) LDTP11844 26.17  LDD1841 
Protein tweety homolog 3 (TTYH3) LDTP11615 57.28  LDD1841 
Protein wntless homolog (WLS) LDTP07156 13.36  LDD1841 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 23.10  LDD1841 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 16.34  LDD1841 
Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) LDTP07610 11.88  LDD1841 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 18.00  LDD1841 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 18.38  LDD1841 
Reduced folate transporter (SLC19A1) LDTP03952 11.00  LDD1841 
Renin receptor (ATP6AP2) LDTP01309 10.27  LDD1841 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 10.56  LDD1841 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 20.82  LDD1841 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 14.12  LDD1841 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 21.11  LDD1841 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 55.33  LDD1841 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 15.35  LDD1841 
Sodium-driven chloride bicarbonate exchanger (SLC4A10) LDTP07649 9.99  LDD1841 
Solute carrier family 12 member 7 (SLC12A7) LDTP14212 10.56  LDD1841 
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 15.14  LDD1841 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 44.32  LDD1841 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 24.93  LDD1841 
Solute carrier family 25 member 35 (SLC25A35) LDTP17106 24.59  LDD1841 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 10.56  LDD1841 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 16.91  LDD1841 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 13.18  LDD1841 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 43.41  LDD1841 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 62.25  LDD1841 
Sugar transporter SWEET1 (SLC50A1) LDTP11136 19.03  LDD1841 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 14.32  LDD1841 
Syntaxin-3 (STX3) LDTP05811 11.71  LDD1841 
Tetraspanin-3 (TSPAN3) LDTP16813 64.00  LDD1841 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 34.30  LDD1841 
Translocation protein SEC62 (SEC62) LDTP15838 9.78  LDD1841 
Translocator protein (TSPO) LDTP03546 11.79  LDD1841 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 51.98  LDD1841 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 12.73  LDD1841 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 15.67  LDD1841 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 10.34  LDD1841 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 20.82  LDD1841 
Transmembrane protein 126A (TMEM126A) LDTP15948 50.56  LDD1841 
Transmembrane protein 199 (TMEM199) LDTP08881 38.59  LDD1841 
Transmembrane protein 201 (TMEM201) LDTP07058 14.52  LDD1841 
Transmembrane protein 205 (TMEM205) LDTP07667 17.88  LDD1841 
Transmembrane protein 230 (TMEM230) LDTP10065 23.43  LDD1841 
Transmembrane protein 245 (TMEM245) LDTP15979 12.82  LDD1841 
Transmembrane protein 33 (TMEM33) LDTP04787 13.18  LDD1841 
Transmembrane protein 59 (TMEM59) LDTP11406 49.52  LDD1841 
Transmembrane protein 70, mitochondrial (TMEM70) LDTP11229 9.78  LDD1841 
Transportin-1 (TNPO1) LDTP09949 11.00  LDD1841 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 31.12  LDD1841 
Vang-like protein 1 (VANGL1) LDTP09288 9.78  LDD1841 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 42.52  LDD1841 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 55.72  LDD1841 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 18.90  LDD1841 
Wolframin (WFS1) LDTP01380 9.99  LDD1841 
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⏷ Show the Full List of 130 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 14.42  LDD1841 
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3 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 10.06  LDD1841 
Coxsackievirus and adenovirus receptor (CXADR) LDTP05085 13.64  LDD1841 
Leukocyte surface antigen CD47 (CD47) LDTP05572 12.82  LDD1841 
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124 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 10.27  LDD1841 
Anaphase-promoting complex subunit 16 (ANAPC16) LDTP10213 9.78  LDD1841 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 13.18  LDD1841 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 12.13  LDD1841 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 9.78  LDD1841 
Calumenin (CALU) LDTP00887 10.41  LDD1841 
CCR4-NOT transcription complex subunit 2 (CNOT2) LDTP12925 11.00  LDD1841 
Centrin-2 (CETN2) LDTP03926 15.35  LDD1841 
Centromere protein K (CENPK) LDTP11143 12.21  LDD1841 
Clustered mitochondria protein homolog (CLUH) LDTP14486 23.92  LDD1841 
Collectin-12 (COLEC12) LDTP07031 9.92  LDD1841 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 11.71  LDD1841 
Conserved oligomeric Golgi complex subunit 8 (COG8) LDTP10603 9.78  LDD1841 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 60.97  LDD1841 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 14.32  LDD1841 
Divergent protein kinase domain 2A (DIPK2A) LDTP09143 11.47  LDD1841 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 16.91  LDD1841 
DnaJ homolog subfamily C member 16 (DNAJC16) LDTP13863 11.08  LDD1841 
Dynactin subunit 2 (DCTN2) LDTP05922 10.41  LDD1841 
Dynactin subunit 3 (DCTN3) LDTP01359 17.75  LDD1841 
Dynein axonemal assembly factor 5 (DNAAF5) LDTP08387 14.52  LDD1841 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 11.71  LDD1841 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 22.16  LDD1841 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 19.84  LDD1841 
Emerin (EMD) LDTP04356 12.91  LDD1841 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 45.89  LDD1841 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1841 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 9.99  LDD1841 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 11.47  LDD1841 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 10.41  LDD1841 
Galectin-3-binding protein (LGALS3BP) LDTP05558 10.41  LDD1841 
Gamma-tubulin complex component 2 (TUBGCP2) LDTP11159 10.63  LDD1841 
Ganglioside GM2 activator (GM2A) LDTP02927 15.56  LDD1841 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 20.68  LDD1841 
Golgi apparatus protein 1 (GLG1) LDTP09920 10.48  LDD1841 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 31.78  LDD1841 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 12.30  LDD1841 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 12.73  LDD1841 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 10.48  LDD1841 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 14.22  LDD1841 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 9.78  LDD1841 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 11.00  LDD1841 
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA) LDTP01259 10.93  LDD1841 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 11.31  LDD1841 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 19.70  LDD1841 
Kinetochore protein Spc24 (SPC24) LDTP09069 16.80  LDD1841 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 15.35  LDD1841 
Large proline-rich protein BAG6 (BAG6) LDTP04094 9.92  LDD1841 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 15.67  LDD1841 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 10.06  LDD1841 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 9.99  LDD1841 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 38.59  LDD1841 
Mediator of RNA polymerase II transcription subunit 24 (MED24) LDTP01225 23.92  LDD1841 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 18.13  LDD1841 
MICOS complex subunit MIC27 (APOOL) LDTP07718 11.39  LDD1841 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 10.63  LDD1841 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 22.32  LDD1841 
Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B) LDTP14125 10.63  LDD1841 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 12.73  LDD1841 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 22.94  LDD1841 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1841 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 58.49  LDD1841 
Negative elongation factor C/D (NELFCD) LDTP08594 39.40  LDD1841 
Neuferricin (CYB5D2) LDTP15623 11.88  LDD1841 
Neurofilament light polypeptide (NEFL) LDTP02180 10.63  LDD1841 
Neurofilament medium polypeptide (NEFM) LDTP02181 13.74  LDD1841 
Nicastrin (NCSTN) LDTP09787 11.08  LDD1841 
Nuclear inhibitor of protein phosphatase 1 (PPP1R8) LDTP05711 12.47  LDD1841 
Nucleobindin-1 (NUCB1) LDTP05375 54.95  LDD1841 
Nucleobindin-2 (NUCB2) LDTP05160 33.59  LDD1841 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 10.48  LDD1841 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 12.21  LDD1841 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 16.91  LDD1841 
Optic atrophy 3 protein (OPA3) LDTP16006 21.41  LDD1841 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 10.78  LDD1841 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 34.78  LDD1841 
Prohibitin-2 (PHB2) LDTP10924 11.39  LDD1841 
Protein CEBPZOS (CEBPZOS) LDTP18883 51.98  LDD1841 
Protein FAM114A2 (FAM114A2) LDTP16080 13.83  LDD1841 
Protein FAM162A (FAM162A) LDTP10056 19.56  LDD1841 
Protein FAM3C (FAM3C) LDTP09773 12.13  LDD1841 
Protein jagunal homolog 1 (JAGN1) LDTP08904 13.74  LDD1841 
Protein kish-B (TMEM167B) LDTP12545 11.16  LDD1841 
Protein LYRIC (MTDH) LDTP08224 12.21  LDD1841 
Protein SERAC1 (SERAC1) LDTP10487 12.64  LDD1841 
Protein SET (SET) LDTP05277 15.24  LDD1841 
Protein unc-119 homolog A (UNC119) LDTP05868 18.77  LDD1841 
Protein unc-119 homolog B (UNC119B) LDTP00105 26.17  LDD1841 
Protein UXT (UXT) LDTP13125 17.39  LDD1841 
Protein YIF1A (YIF1A) LDTP01494 21.56  LDD1841 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 14.83  LDD1841 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 10.56  LDD1841 
Reticulocalbin-2 (RCN2) LDTP06097 21.56  LDD1841 
Reticulon-2 (RTN2) LDTP01167 16.56  LDD1841 
Reticulon-3 (RTN3) LDTP01522 42.22  LDD1841 
Reticulon-4 (RTN4) LDTP12412 27.10  LDD1841 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 18.90  LDD1841 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 10.13  LDD1841 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 15.56  LDD1841 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 16.56  LDD1841 
Synaptogyrin-2 (SYNGR2) LDTP00859 25.46  LDD1841 
Syntaxin-10 (STX10) LDTP00986 36.76  LDD1841 
Syntaxin-18 (STX18) LDTP13086 37.27  LDD1841 
Syntaxin-7 (STX7) LDTP00632 9.78  LDD1841 
TBC1 domain family member 23 (TBC1D23) LDTP12651 9.71  LDD1841 
Testis-expressed protein 264 (TEX264) LDTP14259 24.93  LDD1841 
Tetraspanin-6 (TSPAN6) LDTP14458 41.07  LDD1841 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 15.24  LDD1841 
Tetratricopeptide repeat protein 39C (TTC39C) LDTP17713 11.96  LDD1841 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 12.13  LDD1841 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 11.00  LDD1841 
TraB domain-containing protein (TRABD) LDTP19963 19.56  LDD1841 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 18.90  LDD1841 
Transducin beta-like protein 2 (TBL2) LDTP16285 9.99  LDD1841 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 9.78  LDD1841 
Translocon-associated protein subunit delta (SSR4) LDTP04425 11.00  LDD1841 
Transmembrane protein 209 (TMEM209) LDTP18272 10.27  LDD1841 
Trophoblast glycoprotein (TPBG) LDTP05960 11.88  LDD1841 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 42.81  LDD1841 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 10.85  LDD1841 
Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) LDTP06808 10.63  LDD1841 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 10.27  LDD1841 
Vimentin (VIM) LDTP02297 10.34  LDD1841 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 12.82  LDD1841 
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⏷ Show the Full List of 124 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1841 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587