Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C161  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 195 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 67.6
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 64.4
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 59.3
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 58.1
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 56.5
 LDTP03540  Heme oxygenase 2 (HMOX2) 53.8
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 53.1
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 52.7
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 41.9
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 37.8
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 37.5
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 37.5
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 36.3
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 35.5
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 34.3
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 32.9
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 32.4
 LDTP02505  Lysosomal protective protein (CTSA) 31.3
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 31.3
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 30.7
 LDTP00589  Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) 30.5
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 30.3
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 30.1
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 28.2
 LDTP03394  Ceramide synthase 1 (CERS1) 28.1
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 27.9
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 27.7
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 27.3
 LDTP02359  Heme oxygenase 1 (HMOX1) 26.7
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 26.7
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 26.5
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 26.0
 LDTP03842  Squalene synthase (FDFT1) 26.0
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 25.6
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 25.6
 LDTP10329  Ceramide synthase 2 (CERS2) 25.5
 LDTP05905  Acid ceramidase (ASAH1) 25.3
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 25.3
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) 24.9
 LDTP15097  All-trans-retinol 13,14-reductase (RETSAT) 24.6
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 24.6
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 24.6
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 24.6
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 24.3
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 24.3
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 24.1
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 23.8
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 23.8
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 23.6
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 23.6
 LDTP11127  ADP-dependent glucokinase (ADPGK) 23.3
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 22.8
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 22.5
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 22.2
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 21.9
 LDTP04246  Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) 21.9
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 21.7
 LDTP09391  Ceramide kinase (CERK) 21.6
 LDTP01769  Dihydrofolate reductase (DHFR) 21.1
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 21.0
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 20.8
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 20.7
 LDTP02837  Beta-galactosidase (GLB1) 20.3
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 20.3
 LDTP03145  Catechol O-methyltransferase (COMT) 20.1
 LDTP01803  Adenosine deaminase (ADA) 20.0
 LDTP09395  Signal peptide peptidase-like 2A (SPPL2A) 20.0
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 19.8
 LDTP00804  E3 ubiquitin-protein ligase RNF13 (RNF13) 19.8
 LDTP13408  Cell division cycle protein 23 homolog (CDC23) 19.6
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 19.6
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 19.6
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 18.8
 LDTP10249  Metalloendopeptidase OMA1, mitochondrial (OMA1) 18.5
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 18.1
 LDTP16025  Ketosamine-3-kinase (FN3KRP) 18.0
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 17.9
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 17.3
 LDTP03417  Proteasome subunit beta type-4 (PSMB4) 17.1
 LDTP00544  Sphingolipid delta(4)-desaturase DES1 (DEGS1) 17.1
 LDTP08265  N-alpha-acetyltransferase 40 (NAA40) 17.0
 LDTP03418  Proteasome subunit beta type-6 (PSMB6) 17.0
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 16.9
 LDTP11081  NAD-capped RNA hydrolase NUDT12 (NUDT12) 16.9
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 16.6
 LDTP06617  Ceramide glucosyltransferase (UGCG) 16.4
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 16.3
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 16.2
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 16.2
 LDTP04114  E3 ubiquitin-protein ligase NEDD4 (NEDD4) 16.1
 LDTP07831  Transmembrane protein with metallophosphoesterase domain (TMPPE) 16.1
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 16.0
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 15.8
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 15.6
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 15.6
 LDTP05409  Antigen peptide transporter 2 (TAP2) 15.3
 LDTP14278  Sulfide:quinone oxidoreductase, mitochondrial (SQOR) 15.3
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 15.1
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 15.1
 LDTP10699  E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) 15.0
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 14.9
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 14.8
 LDTP04471  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) 14.5
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 14.3
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 14.2
 LDTP14264  Choline/ethanolaminephosphotransferase 1 (CEPT1) 14.2
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 14.2
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 14.1
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 14.0
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 14.0
 LDTP10020  Ras-related protein Rab-24 (RAB24) 14.0
 LDTP06849  Prolyl endopeptidase-like (PREPL) 13.8
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 13.7
 LDTP00462  Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) 13.6
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 13.6
 LDTP08017  Endoplasmic reticulum metallopeptidase 1 (ERMP1) 13.5
 LDTP07756  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) 13.5
 LDTP01562  Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) 13.5
 LDTP05029  Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) 13.4
 LDTP11437  Peroxisomal trans-2-enoyl-CoA reductase (PECR) 13.3
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 13.2
 LDTP16040  Glyoxalase domain-containing protein 4 (GLOD4) 13.1
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 12.9
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 12.9
 LDTP07868  Protein O-mannosyl-transferase TMTC3 (TMTC3) 12.9
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 12.9
 LDTP06986  Rab-like protein 3 (RABL3) 12.8
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 12.7
 LDTP03787  Choline kinase alpha (CHKA) 12.6
 LDTP02539  Lysosomal acid phosphatase (ACP2) 12.6
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 12.6
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 12.4
 LDTP02141  Alpha-galactosidase A (GLA) 12.3
 LDTP00836  ATPase GET3 (GET3) 12.2
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 12.1
 LDTP12444  Xaa-Pro aminopeptidase 1 (XPNPEP1) 12.1
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 12.0
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 12.0
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 12.0
 LDTP09043  Lysine-specific histone demethylase 2 (KDM1B) 12.0
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 12.0
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 11.9
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B) 11.9
 LDTP07503  Endoplasmic reticulum aminopeptidase 2 (ERAP2) 11.8
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 11.8
 LDTP11319  Threonine--tRNA ligase, mitochondrial (TARS2) 11.7
 LDTP04247  Protein farnesyltransferase subunit beta (FNTB) 11.6
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 11.6
 LDTP01759  Histone-lysine N-methyltransferase NSD2 (NSD2) 11.6
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 11.6
 LDTP15132  2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3) 11.5
 LDTP09251  Atlastin-2 (ATL2) 11.5
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 11.5
 LDTP10163  m7GpppX diphosphatase (DCPS) 11.3
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 11.3
 LDTP15155  Thiol S-methyltransferase TMT1B (TMT1B) 11.3
 LDTP17247  5'-nucleotidase domain-containing protein 1 (NT5DC1) 11.2
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 11.2
 LDTP00988  Protein O-GlcNAcase (OGA) 11.0
 LDTP13131  7-dehydrocholesterol reductase (DHCR7) 10.9
 LDTP03822  Activin receptor type-1B (ACVR1B) 10.9
 LDTP08378  Serine/threonine-protein kinase VRK2 (VRK2) 10.9
 LDTP07873  Acyl-CoA dehydrogenase family member 11 (ACAD11) 10.8
 LDTP13352  GTP:AMP phosphotransferase AK3, mitochondrial (AK3) 10.8
 LDTP10530  Beta-1,3-galactosyltransferase 6 (B3GALT6) 10.7
 LDTP07057  Protein phosphatase 1L (PPM1L) 10.7
 LDTP00975  Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) 10.6
 LDTP00886  Nardilysin (NRDC) 10.6
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 10.6
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 10.5
 LDTP01329  Lathosterol oxidase (SC5D) 10.5
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 10.5
 LDTP05408  Antigen peptide transporter 1 (TAP1) 10.4
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 10.4
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 10.4
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 10.3
 LDTP03608  RAC-beta serine/threonine-protein kinase (AKT2) 10.3
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 10.2
 LDTP07961  Protein arginine methyltransferase NDUFAF7, mitochondrial (NDUFAF7) 10.2
 LDTP06779  Triokinase/FMN cyclase (TKFC) 10.2
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 10.1
 LDTP04263  Cysteine--tRNA ligase, cytoplasmic (CARS1) 10.1
 LDTP02721  Farnesyl pyrophosphate synthase (FDPS) 10.1
 LDTP10101  Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) 10.1
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 10.1
 LDTP10676  Inositol polyphosphate-4-phosphatase type I A (INPP4A) 10.0
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 10.0
 LDTP11199  DCN1-like protein 5 (DCUN1D5) 9.9
 LDTP00783  Beta-1,4-glucuronyltransferase 1 (B4GAT1) 9.8
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 9.8
 LDTP00518  Histone-lysine N-methyltransferase SETD1A (SETD1A) 9.8
 LDTP06750  Prolyl 3-hydroxylase 1 (P3H1) 9.8
 LDTP06511  Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) 9.8
 LDTP04080  Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (PHKA1) 9.8
Transporter and channel
Click to Show/Hide to Show 130 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 99.7
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 69.1
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 67.2
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 64.4
 LDTP16813  Tetraspanin-3 (TSPAN3) 64.0
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 62.2
 LDTP11615  Protein tweety homolog 3 (TTYH3) 57.3
 LDTP07236  Protein GPR107 (GPR107) 56.5
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 55.7
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 55.3
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 52.0
 LDTP15948  Transmembrane protein 126A (TMEM126A) 50.6
 LDTP11406  Transmembrane protein 59 (TMEM59) 49.5
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 47.2
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 44.3
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 43.4
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 42.5
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 39.4
 LDTP16163  Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) 39.4
 LDTP08881  Transmembrane protein 199 (TMEM199) 38.6
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 35.0
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 35.0
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 34.3
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 31.1
 LDTP01217  Metaxin-2 (MTX2) 30.7
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 29.7
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 29.0
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 27.9
 LDTP12383  Protein GPR108 (GPR108) 26.9
 LDTP11844  Protein spinster homolog 1 (SPNS1) 26.2
 LDTP02215  Prosaposin (PSAP) 25.1
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 24.9
 LDTP17106  Solute carrier family 25 member 35 (SLC25A35) 24.6
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 24.4
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 24.3
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 24.1
 LDTP05900  Metaxin-1 (MTX1) 23.9
 LDTP11245  Derlin-1 (DERL1) 23.8
 LDTP10065  Transmembrane protein 230 (TMEM230) 23.4
 LDTP08016  Proton-coupled amino acid transporter 1 (SLC36A1) 23.1
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 21.1
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 21.0
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 20.8
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 20.8
 LDTP12451  Integral membrane protein 2C (ITM2C) 19.4
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 19.4
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 19.3
 LDTP11136  Sugar transporter SWEET1 (SLC50A1) 19.0
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 18.9
 LDTP02071  Amyloid-beta precursor protein (APP) 18.4
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 18.4
 LDTP11213  Nucleoporin NDC1 (NDC1) 18.3
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 18.1
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 18.1
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 18.1
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 18.0
 LDTP07667  Transmembrane protein 205 (TMEM205) 17.9
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 17.8
 LDTP04463  H(+)/Cl(-) exchange transporter 7 (CLCN7) 17.8
 LDTP13833  Integral membrane protein 2B (ITM2B) 17.6
 LDTP14181  Peroxisomal membrane protein PEX16 (PEX16) 17.5
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 17.4
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 17.1
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 16.9
 LDTP15648  BRI3-binding protein (BRI3BP) 16.8
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 16.8
 LDTP02655  Lysosome-associated membrane glycoprotein 2 (LAMP2) 16.3
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 16.3
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 16.0
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 15.7
 LDTP14275  Sodium bicarbonate cotransporter 3 (SLC4A7) 15.3
 LDTP02544  Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) 15.1
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 15.0
 LDTP09028  Mitoguardin 1 (MIGA1) 15.0
 LDTP12704  Anoctamin-10 (ANO10) 14.9
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 14.5
 LDTP07058  Transmembrane protein 201 (TMEM201) 14.5
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 14.3
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 14.1
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 13.8
 LDTP16190  Protein FAM8A1 (FAM8A1) 13.8
 LDTP07156  Protein wntless homolog (WLS) 13.4
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 13.2
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 13.2
 LDTP04787  Transmembrane protein 33 (TMEM33) 13.2
 LDTP04501  Importin subunit alpha-1 (KPNA2) 12.9
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 12.8
 LDTP15979  Transmembrane protein 245 (TMEM245) 12.8
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 12.7
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 12.6
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 12.5
 LDTP11250  MICOS complex subunit MIC26 (APOO) 12.4
 LDTP11116  45 kDa calcium-binding protein (SDF4) 11.9
 LDTP06198  Major facilitator superfamily domain-containing protein 10 (MFSD10) 11.9
 LDTP07610  Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) 11.9
 LDTP03546  Translocator protein (TSPO) 11.8
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 11.7
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 11.7
 LDTP05811  Syntaxin-3 (STX3) 11.7
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 11.6
 LDTP04940  NPC intracellular cholesterol transporter 2 (NPC2) 11.6
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 11.5
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 11.4
 LDTP11634  Derlin-2 (DERL2) 11.2
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 11.2
 LDTP03952  Reduced folate transporter (SLC19A1) 11.0
 LDTP09949  Transportin-1 (TNPO1) 11.0
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 10.9
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 10.9
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 10.9
 LDTP00590  Protein RER1 (RER1) 10.6
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 10.6
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 10.6
 LDTP14212  Solute carrier family 12 member 7 (SLC12A7) 10.6
 LDTP15733  Solute carrier family 25 member 44 (SLC25A44) 10.6
 LDTP06855  Anoctamin-6 (ANO6) 10.5
 LDTP09144  Metal transporter CNNM3 (CNNM3) 10.3
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 10.3
 LDTP01309  Renin receptor (ATP6AP2) 10.3
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 10.1
 LDTP10754  Pannexin-1 (PANX1) 10.0
 LDTP07649  Sodium-driven chloride bicarbonate exchanger (SLC4A10) 10.0
 LDTP01380  Wolframin (WFS1) 10.0
 LDTP08673  Calcium uptake protein 2, mitochondrial (MICU2) 9.9
 LDTP15838  Translocation protein SEC62 (SEC62) 9.8
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 9.8
 LDTP09288  Vang-like protein 1 (VANGL1) 9.8
 LDTP07537  Metal transporter CNNM4 (CNNM4) 9.7
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 14.4
Immunoglobulin
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05085  Coxsackievirus and adenovirus receptor (CXADR) 13.6
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 12.8
 LDTP03772  Basigin (BSG) 10.1
Other
Click to Show/Hide to Show 124 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 61.0
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 58.5
 LDTP05375  Nucleobindin-1 (NUCB1) 54.9
 LDTP18883  Protein CEBPZOS (CEBPZOS) 52.0
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 45.9
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 42.8
 LDTP01522  Reticulon-3 (RTN3) 42.2
 LDTP14458  Tetraspanin-6 (TSPAN6) 41.1
 LDTP08594  Negative elongation factor C/D (NELFCD) 39.4
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 38.6
 LDTP13086  Syntaxin-18 (STX18) 37.3
 LDTP00986  Syntaxin-10 (STX10) 36.8
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 34.8
 LDTP05160  Nucleobindin-2 (NUCB2) 33.6
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 31.8
 LDTP12412  Reticulon-4 (RTN4) 27.1
 LDTP00105  Protein unc-119 homolog B (UNC119B) 26.2
 LDTP00859  Synaptogyrin-2 (SYNGR2) 25.5
 LDTP14259  Testis-expressed protein 264 (TEX264) 24.9
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 23.9
 LDTP01225  Mediator of RNA polymerase II transcription subunit 24 (MED24) 23.9
 LDTP14126  Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) 22.9
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 22.3
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 22.2
 LDTP01494  Protein YIF1A (YIF1A) 21.6
 LDTP06097  Reticulocalbin-2 (RCN2) 21.6
 LDTP16006  Optic atrophy 3 protein (OPA3) 21.4
 LDTP03729  General transcription factor IIF subunit 1 (GTF2F1) 20.7
 LDTP15701  EF-hand domain-containing protein D2 (EFHD2) 19.8
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 19.7
 LDTP10056  Protein FAM162A (FAM162A) 19.6
 LDTP19963  TraB domain-containing protein (TRABD) 19.6
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 18.9
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 18.9
 LDTP05868  Protein unc-119 homolog A (UNC119) 18.8
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 18.1
 LDTP01359  Dynactin subunit 3 (DCTN3) 17.8
 LDTP13125  Protein UXT (UXT) 17.4
 LDTP13802  DNA replication complex GINS protein PSF2 (GINS2) 16.9
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 16.9
 LDTP09069  Kinetochore protein Spc24 (SPC24) 16.8
 LDTP01167  Reticulon-2 (RTN2) 16.6
 LDTP07934  Synaptic vesicle glycoprotein 2A (SV2A) 16.6
 LDTP15269  Large ribosomal subunit protein mL55 (MRPL55) 15.7
 LDTP02927  Ganglioside GM2 activator (GM2A) 15.6
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 15.6
 LDTP03926  Centrin-2 (CETN2) 15.3
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 15.3
 LDTP05277  Protein SET (SET) 15.2
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 15.2
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 14.8
 LDTP08387  Dynein axonemal assembly factor 5 (DNAAF5) 14.5
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 14.3
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 14.2
 LDTP16080  Protein FAM114A2 (FAM114A2) 13.8
 LDTP02181  Neurofilament medium polypeptide (NEFM) 13.7
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 13.7
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 13.2
 LDTP04356  Emerin (EMD) 12.9
 LDTP12623  Zinc finger CCHC domain-containing protein 3 (ZCCHC3) 12.8
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 12.7
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 12.7
 LDTP10487  Protein SERAC1 (SERAC1) 12.6
 LDTP05711  Nuclear inhibitor of protein phosphatase 1 (PPP1R8) 12.5
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 12.3
 LDTP11143  Centromere protein K (CENPK) 12.2
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 12.2
 LDTP08224  Protein LYRIC (MTDH) 12.2
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 12.1
 LDTP09773  Protein FAM3C (FAM3C) 12.1
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 12.1
 LDTP17713  Tetratricopeptide repeat protein 39C (TTC39C) 12.0
 LDTP15623  Neuferricin (CYB5D2) 11.9
 LDTP05960  Trophoblast glycoprotein (TPBG) 11.9
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 11.7
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 11.7
 LDTP09143  Divergent protein kinase domain 2A (DIPK2A) 11.5
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 11.5
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 11.4
 LDTP10924  Prohibitin-2 (PHB2) 11.4
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 11.3
 LDTP12545  Protein kish-B (TMEM167B) 11.2
 LDTP13863  DnaJ homolog subfamily C member 16 (DNAJC16) 11.1
 LDTP09787  Nicastrin (NCSTN) 11.1
 LDTP12925  CCR4-NOT transcription complex subunit 2 (CNOT2) 11.0
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 11.0
 LDTP12780  THUMP domain-containing protein 1 (THUMPD1) 11.0
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 11.0
 LDTP01259  Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA) 10.9
 LDTP17652  Uncharacterized protein KIAA2013 (KIAA2013) 10.9
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 10.8
 LDTP11159  Gamma-tubulin complex component 2 (TUBGCP2) 10.6
 LDTP00871  Microtubule nucleation factor SSNA1 (SSNA1) 10.6
 LDTP14125  Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B) 10.6
 LDTP02180  Neurofilament light polypeptide (NEFL) 10.6
 LDTP06808  Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) 10.6
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 10.6
 LDTP09920  Golgi apparatus protein 1 (GLG1) 10.5
 LDTP03615  Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) 10.5
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 10.5
 LDTP00887  Calumenin (CALU) 10.4
 LDTP05922  Dynactin subunit 2 (DCTN2) 10.4
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 10.4
 LDTP05558  Galectin-3-binding protein (LGALS3BP) 10.4
 LDTP02297  Vimentin (VIM) 10.3
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 10.3
 LDTP18272  Transmembrane protein 209 (TMEM209) 10.3
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 10.3
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 10.1
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1) 10.1
 LDTP04853  Eukaryotic translation initiation factor 3 subunit E (EIF3E) 10.0
 LDTP14217  Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) 10.0
 LDTP16285  Transducin beta-like protein 2 (TBL2) 10.0
 LDTP07031  Collectin-12 (COLEC12) 9.9
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 9.9
 LDTP10213  Anaphase-promoting complex subunit 16 (ANAPC16) 9.8
 LDTP07598  BRCA1-associated ATM activator 1 (BRAT1) 9.8
 LDTP10603  Conserved oligomeric Golgi complex subunit 8 (COG8) 9.8
 LDTP00991  Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) 9.8
 LDTP00632  Syntaxin-7 (STX7) 9.8
 LDTP12476  Translation initiation factor eIF2B subunit gamma (EIF2B3) 9.8
 LDTP12651  TBC1 domain family member 23 (TBC1D23) 9.7

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587