Details of the Target

General Information of Target

Target ID LDTP15701
Target Name EF-hand domain-containing protein D2 (EFHD2)
Gene Name EFHD2
Gene ID 79180
Synonyms
SWS1; EF-hand domain-containing protein D2; Swiprosin-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MESGLAGNGTGAGLVMKVKQEKPERLLQTLAPQAMLVEKDKENIFQQHRGLPPRQTMGRP
RALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSSGEGHFVCLDCGKRFSWWS
SLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQHLLK
HQKTHSRPATHSCPECERCFRHQVGLRIHQRAHARDRQGSRAGLHELIQDAAARRACRLQ
PGPPRGRPEWAWLGLCQGWWGQPGARAAVSGPEGPGEPRQFICNECGKSFTWWSSLNIHQ
RIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTHL
PGAQAAPCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQ
RSPGARDTLWGRGQAGLAGPGEPRQFICNECGKSFSWWSALTIHQRIHTGERPYPCPECG
RRFSQKPNLTRHRRNHTGERPYLCPACGRGFSQKQHLLKHQRVHRAAPACSPKEEAR
Target Bioclass
Other
Subcellular location
Membrane raft
Function
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Uniprot ID
Q96C19
Ensemble ID
ENST00000375980.9
HGNC ID
HGNC:28670

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 31 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
AZ-9
 Probe Info  		7.39  LDD0393  [2]
CY-1
 Probe Info  		100.00  LDD0243  [3]
SAA-alkyne
 Probe Info  		1.16  LDD0252  [4]
YN-1
 Probe Info  		100.00  LDD0444  [5]
ONAyne
 Probe Info  		K87(5.28)  LDD0274  [6]
STPyne
 Probe Info  		K102(10.00); K134(9.69); K188(10.00); K191(10.00)  LDD0277  [6]
BTD
 Probe Info  		C172(1.12)  LDD2089  [7]
DA-P3
 Probe Info  		4.15  LDD0179  [8]
AHL-Pu-1
 Probe Info  		C53(6.72)  LDD0168  [9]
EA-probe
 Probe Info  		N.A.  LDD0440  [10]
DBIA
 Probe Info  		C172(1.04); C53(0.95)  LDD0078  [11]
ATP probe
 Probe Info  		N.A.  LDD0199  [12]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [13]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [13]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [13]
NAIA_4
 Probe Info  		N.A.  LDD2226  [14]
NAIA_5
 Probe Info  		N.A.  LDD2224  [14]
WYneN
 Probe Info  		N.A.  LDD0021  [15]
WYneO
 Probe Info  		N.A.  LDD0022  [15]
Compound 10
 Probe Info  		N.A.  LDD2216  [16]
Compound 11
 Probe Info  		N.A.  LDD2213  [16]
IPM
 Probe Info  		N.A.  LDD0005  [15]
NHS
 Probe Info  		N.A.  LDD0010  [15]
PF-06672131
 Probe Info  		N.A.  LDD0017  [17]
TFBX
 Probe Info  		N.A.  LDD0148  [18]
VSF
 Probe Info  		N.A.  LDD0007  [15]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [19]
Acrolein
 Probe Info  		N.A.  LDD0217  [20]
Methacrolein
 Probe Info  		N.A.  LDD0218  [20]
AOyne
 Probe Info  		15.00  LDD0443  [21]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C159
 Probe Info  		11.47  LDD1839  [22]
C160
 Probe Info  		8.82  LDD1840  [22]
C161
 Probe Info  		19.84  LDD1841  [22]
CR-1
 Probe Info  		2.53  LDD0430  [23]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C172(0.70)  LDD2112  [7]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C172(0.88)  LDD2117  [7]
 LDCM0025  4SU-RNA HEK-293T C53(6.72)  LDD0168  [9]
 LDCM0026  4SU-RNA+native RNA HEK-293T C172(3.09)  LDD0169  [9]
 LDCM0214  AC1 HCT 116 C172(1.04)  LDD0531  [11]
 LDCM0215  AC10 HCT 116 C172(1.08)  LDD0532  [11]
 LDCM0216  AC100 HCT 116 C172(1.08)  LDD0533  [11]
 LDCM0217  AC101 HCT 116 C172(1.10)  LDD0534  [11]
 LDCM0218  AC102 HCT 116 C172(1.17)  LDD0535  [11]
 LDCM0219  AC103 HCT 116 C172(1.42)  LDD0536  [11]
 LDCM0220  AC104 HCT 116 C172(1.23)  LDD0537  [11]
 LDCM0221  AC105 HCT 116 C172(1.16)  LDD0538  [11]
 LDCM0222  AC106 HCT 116 C172(1.39)  LDD0539  [11]
 LDCM0223  AC107 HCT 116 C172(1.30)  LDD0540  [11]
 LDCM0224  AC108 HCT 116 C172(1.07)  LDD0541  [11]
 LDCM0225  AC109 HCT 116 C172(0.92)  LDD0542  [11]
 LDCM0226  AC11 HCT 116 C172(1.17)  LDD0543  [11]
 LDCM0227  AC110 HCT 116 C172(1.00)  LDD0544  [11]
 LDCM0228  AC111 HCT 116 C172(1.04)  LDD0545  [11]
 LDCM0229  AC112 HCT 116 C172(1.20)  LDD0546  [11]
 LDCM0230  AC113 HCT 116 C172(0.98)  LDD0547  [11]
 LDCM0231  AC114 HCT 116 C172(1.01)  LDD0548  [11]
 LDCM0232  AC115 HCT 116 C172(0.87)  LDD0549  [11]
 LDCM0233  AC116 HCT 116 C172(0.91)  LDD0550  [11]
 LDCM0234  AC117 HCT 116 C172(0.92)  LDD0551  [11]
 LDCM0235  AC118 HCT 116 C172(0.95)  LDD0552  [11]
 LDCM0236  AC119 HCT 116 C172(1.00)  LDD0553  [11]
 LDCM0237  AC12 HCT 116 C172(1.05)  LDD0554  [11]
 LDCM0238  AC120 HCT 116 C172(1.03)  LDD0555  [11]
 LDCM0239  AC121 HCT 116 C172(0.85)  LDD0556  [11]
 LDCM0240  AC122 HCT 116 C172(0.95)  LDD0557  [11]
 LDCM0241  AC123 HCT 116 C172(0.90)  LDD0558  [11]
 LDCM0242  AC124 HCT 116 C172(0.96)  LDD0559  [11]
 LDCM0243  AC125 HCT 116 C172(0.88)  LDD0560  [11]
 LDCM0244  AC126 HCT 116 C172(0.87)  LDD0561  [11]
 LDCM0245  AC127 HCT 116 C172(0.87)  LDD0562  [11]
 LDCM0246  AC128 HCT 116 C172(1.49)  LDD0563  [11]
 LDCM0247  AC129 HCT 116 C172(1.03)  LDD0564  [11]
 LDCM0249  AC130 HCT 116 C172(1.34)  LDD0566  [11]
 LDCM0250  AC131 HCT 116 C172(0.95)  LDD0567  [11]
 LDCM0251  AC132 HCT 116 C172(1.13)  LDD0568  [11]
 LDCM0252  AC133 HCT 116 C172(1.24)  LDD0569  [11]
 LDCM0253  AC134 HCT 116 C172(1.44)  LDD0570  [11]
 LDCM0254  AC135 HCT 116 C172(1.15)  LDD0571  [11]
 LDCM0255  AC136 HCT 116 C172(1.21)  LDD0572  [11]
 LDCM0256  AC137 HCT 116 C172(1.14)  LDD0573  [11]
 LDCM0257  AC138 HCT 116 C172(1.58)  LDD0574  [11]
 LDCM0258  AC139 HCT 116 C172(1.55)  LDD0575  [11]
 LDCM0259  AC14 HCT 116 C172(0.90)  LDD0576  [11]
 LDCM0260  AC140 HCT 116 C172(1.48)  LDD0577  [11]
 LDCM0261  AC141 HCT 116 C172(1.52)  LDD0578  [11]
 LDCM0262  AC142 HCT 116 C172(1.00)  LDD0579  [11]
 LDCM0263  AC143 HCT 116 C172(1.25)  LDD0580  [11]
 LDCM0264  AC144 HCT 116 C172(1.38)  LDD0581  [11]
 LDCM0265  AC145 HCT 116 C172(1.25)  LDD0582  [11]
 LDCM0266  AC146 HCT 116 C172(1.38)  LDD0583  [11]
 LDCM0267  AC147 HCT 116 C172(1.43)  LDD0584  [11]
 LDCM0268  AC148 HCT 116 C172(1.99)  LDD0585  [11]
 LDCM0269  AC149 HCT 116 C172(1.73)  LDD0586  [11]
 LDCM0270  AC15 HCT 116 C172(1.24)  LDD0587  [11]
 LDCM0271  AC150 HCT 116 C172(1.27)  LDD0588  [11]
 LDCM0272  AC151 HCT 116 C172(1.22)  LDD0589  [11]
 LDCM0273  AC152 HCT 116 C172(1.61)  LDD0590  [11]
 LDCM0274  AC153 HCT 116 C172(2.07)  LDD0591  [11]
 LDCM0621  AC154 HCT 116 C172(1.39)  LDD2158  [11]
 LDCM0622  AC155 HCT 116 C172(1.47)  LDD2159  [11]
 LDCM0623  AC156 HCT 116 C172(1.23)  LDD2160  [11]
 LDCM0624  AC157 HCT 116 C172(1.09)  LDD2161  [11]
 LDCM0276  AC17 HCT 116 C172(1.78)  LDD0593  [11]
 LDCM0277  AC18 HCT 116 C172(1.98)  LDD0594  [11]
 LDCM0278  AC19 HCT 116 C172(1.36)  LDD0595  [11]
 LDCM0279  AC2 HCT 116 C172(1.02)  LDD0596  [11]
 LDCM0280  AC20 HCT 116 C172(1.11)  LDD0597  [11]
 LDCM0281  AC21 HCT 116 C172(1.80)  LDD0598  [11]
 LDCM0282  AC22 HCT 116 C172(1.20)  LDD0599  [11]
 LDCM0283  AC23 HCT 116 C172(1.31)  LDD0600  [11]
 LDCM0284  AC24 HCT 116 C172(1.13)  LDD0601  [11]
 LDCM0285  AC25 HCT 116 C172(0.95)  LDD0602  [11]
 LDCM0286  AC26 HCT 116 C172(1.05)  LDD0603  [11]
 LDCM0287  AC27 HCT 116 C172(0.93)  LDD0604  [11]
 LDCM0288  AC28 HCT 116 C172(0.96)  LDD0605  [11]
 LDCM0289  AC29 HCT 116 C172(1.29)  LDD0606  [11]
 LDCM0290  AC3 HCT 116 C172(0.93)  LDD0607  [11]
 LDCM0291  AC30 HCT 116 C172(1.26)  LDD0608  [11]
 LDCM0292  AC31 HCT 116 C172(1.07)  LDD0609  [11]
 LDCM0293  AC32 HCT 116 C172(1.13)  LDD0610  [11]
 LDCM0294  AC33 HCT 116 C172(0.97)  LDD0611  [11]
 LDCM0295  AC34 HCT 116 C172(1.02)  LDD0612  [11]
 LDCM0296  AC35 HCT 116 C172(0.87)  LDD0613  [11]
 LDCM0297  AC36 HCT 116 C172(0.86)  LDD0614  [11]
 LDCM0298  AC37 HCT 116 C172(0.88)  LDD0615  [11]
 LDCM0299  AC38 HCT 116 C172(0.90)  LDD0616  [11]
 LDCM0300  AC39 HCT 116 C172(0.98)  LDD0617  [11]
 LDCM0301  AC4 HCT 116 C172(0.86)  LDD0618  [11]
 LDCM0302  AC40 HCT 116 C172(1.09)  LDD0619  [11]
 LDCM0303  AC41 HCT 116 C172(0.91)  LDD0620  [11]
 LDCM0304  AC42 HCT 116 C172(1.02)  LDD0621  [11]
 LDCM0305  AC43 HCT 116 C172(0.97)  LDD0622  [11]
 LDCM0306  AC44 HCT 116 C172(1.02)  LDD0623  [11]
 LDCM0307  AC45 HCT 116 C172(1.15)  LDD0624  [11]
 LDCM0308  AC46 HCT 116 C172(1.19)  LDD0625  [11]
 LDCM0309  AC47 HCT 116 C172(0.96)  LDD0626  [11]
 LDCM0310  AC48 HCT 116 C172(1.06)  LDD0627  [11]
 LDCM0311  AC49 HCT 116 C172(1.30)  LDD0628  [11]
 LDCM0312  AC5 HCT 116 C172(0.86)  LDD0629  [11]
 LDCM0313  AC50 HCT 116 C172(1.19)  LDD0630  [11]
 LDCM0314  AC51 HCT 116 C172(1.15)  LDD0631  [11]
 LDCM0315  AC52 HCT 116 C172(1.05)  LDD0632  [11]
 LDCM0316  AC53 HCT 116 C172(0.94)  LDD0633  [11]
 LDCM0317  AC54 HCT 116 C172(0.95)  LDD0634  [11]
 LDCM0318  AC55 HCT 116 C172(1.12)  LDD0635  [11]
 LDCM0319  AC56 HCT 116 C172(1.08)  LDD0636  [11]
 LDCM0320  AC57 HCT 116 C172(1.33)  LDD0637  [11]
 LDCM0321  AC58 HCT 116 C172(1.33)  LDD0638  [11]
 LDCM0322  AC59 HCT 116 C172(1.29)  LDD0639  [11]
 LDCM0323  AC6 HCT 116 C172(1.16)  LDD0640  [11]
 LDCM0324  AC60 HCT 116 C172(1.39)  LDD0641  [11]
 LDCM0325  AC61 HCT 116 C172(1.32)  LDD0642  [11]
 LDCM0326  AC62 HCT 116 C172(1.30)  LDD0643  [11]
 LDCM0327  AC63 HCT 116 C172(1.26)  LDD0644  [11]
 LDCM0328  AC64 HCT 116 C172(1.20)  LDD0645  [11]
 LDCM0329  AC65 HCT 116 C172(1.45)  LDD0646  [11]
 LDCM0330  AC66 HCT 116 C172(1.41)  LDD0647  [11]
 LDCM0331  AC67 HCT 116 C172(1.49)  LDD0648  [11]
 LDCM0332  AC68 HCT 116 C172(0.79)  LDD0649  [11]
 LDCM0333  AC69 HCT 116 C172(0.77)  LDD0650  [11]
 LDCM0334  AC7 HCT 116 C172(1.19)  LDD0651  [11]
 LDCM0335  AC70 HCT 116 C172(1.02)  LDD0652  [11]
 LDCM0336  AC71 HCT 116 C172(0.75)  LDD0653  [11]
 LDCM0337  AC72 HCT 116 C172(1.01)  LDD0654  [11]
 LDCM0338  AC73 HCT 116 C172(1.04)  LDD0655  [11]
 LDCM0339  AC74 HCT 116 C172(0.93)  LDD0656  [11]
 LDCM0340  AC75 HCT 116 C172(1.05)  LDD0657  [11]
 LDCM0341  AC76 HCT 116 C172(0.82)  LDD0658  [11]
 LDCM0342  AC77 HCT 116 C172(0.92)  LDD0659  [11]
 LDCM0343  AC78 HCT 116 C172(0.84)  LDD0660  [11]
 LDCM0344  AC79 HCT 116 C172(0.83)  LDD0661  [11]
 LDCM0345  AC8 HCT 116 C172(1.14)  LDD0662  [11]
 LDCM0346  AC80 HCT 116 C172(0.96)  LDD0663  [11]
 LDCM0347  AC81 HCT 116 C172(0.82)  LDD0664  [11]
 LDCM0348  AC82 HCT 116 C172(1.01)  LDD0665  [11]
 LDCM0349  AC83 HCT 116 C172(1.24)  LDD0666  [11]
 LDCM0350  AC84 HCT 116 C172(1.25)  LDD0667  [11]
 LDCM0351  AC85 HCT 116 C172(1.37)  LDD0668  [11]
 LDCM0352  AC86 HCT 116 C172(1.21)  LDD0669  [11]
 LDCM0353  AC87 HCT 116 C172(1.10)  LDD0670  [11]
 LDCM0354  AC88 HCT 116 C172(1.17)  LDD0671  [11]
 LDCM0355  AC89 HCT 116 C172(1.08)  LDD0672  [11]
 LDCM0357  AC90 HCT 116 C172(1.11)  LDD0674  [11]
 LDCM0358  AC91 HCT 116 C172(1.05)  LDD0675  [11]
 LDCM0359  AC92 HCT 116 C172(1.17)  LDD0676  [11]
 LDCM0360  AC93 HCT 116 C172(1.29)  LDD0677  [11]
 LDCM0361  AC94 HCT 116 C172(1.07)  LDD0678  [11]
 LDCM0362  AC95 HCT 116 C172(1.25)  LDD0679  [11]
 LDCM0363  AC96 HCT 116 C172(1.05)  LDD0680  [11]
 LDCM0364  AC97 HCT 116 C172(1.43)  LDD0681  [11]
 LDCM0365  AC98 HCT 116 C172(1.92)  LDD0682  [11]
 LDCM0366  AC99 HCT 116 C172(1.12)  LDD0683  [11]
 LDCM0248  AKOS034007472 HCT 116 C172(0.87)  LDD0565  [11]
 LDCM0356  AKOS034007680 HCT 116 C172(1.10)  LDD0673  [11]
 LDCM0275  AKOS034007705 HCT 116 C172(1.48)  LDD0592  [11]
 LDCM0156  Aniline NCI-H1299 12.04  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C172(1.04); C53(0.95)  LDD0078  [11]
 LDCM0630  CCW28-3 231MFP C172(0.64)  LDD2214  [24]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [20]
 LDCM0367  CL1 HCT 116 C172(1.00)  LDD0684  [11]
 LDCM0368  CL10 HCT 116 C172(1.16)  LDD0685  [11]
 LDCM0369  CL100 HCT 116 C172(1.10)  LDD0686  [11]
 LDCM0370  CL101 HCT 116 C172(1.21)  LDD0687  [11]
 LDCM0371  CL102 HCT 116 C172(1.21)  LDD0688  [11]
 LDCM0372  CL103 HCT 116 C172(1.00)  LDD0689  [11]
 LDCM0373  CL104 HCT 116 C172(1.14)  LDD0690  [11]
 LDCM0374  CL105 HCT 116 C172(1.34)  LDD0691  [11]
 LDCM0375  CL106 HCT 116 C172(2.06)  LDD0692  [11]
 LDCM0376  CL107 HCT 116 C172(1.43)  LDD0693  [11]
 LDCM0377  CL108 HCT 116 C172(1.52)  LDD0694  [11]
 LDCM0378  CL109 HCT 116 C172(1.28)  LDD0695  [11]
 LDCM0379  CL11 HCT 116 C172(1.20)  LDD0696  [11]
 LDCM0380  CL110 HCT 116 C172(1.76)  LDD0697  [11]
 LDCM0381  CL111 HCT 116 C172(1.52)  LDD0698  [11]
 LDCM0382  CL112 HCT 116 C172(1.16)  LDD0699  [11]
 LDCM0383  CL113 HCT 116 C172(1.07)  LDD0700  [11]
 LDCM0384  CL114 HCT 116 C172(1.60)  LDD0701  [11]
 LDCM0385  CL115 HCT 116 C172(1.17)  LDD0702  [11]
 LDCM0386  CL116 HCT 116 C172(1.00)  LDD0703  [11]
 LDCM0387  CL117 HCT 116 C172(1.41)  LDD0704  [11]
 LDCM0388  CL118 HCT 116 C172(1.08)  LDD0705  [11]
 LDCM0389  CL119 HCT 116 C172(1.11)  LDD0706  [11]
 LDCM0390  CL12 HCT 116 C172(1.31)  LDD0707  [11]
 LDCM0391  CL120 HCT 116 C172(1.08)  LDD0708  [11]
 LDCM0392  CL121 HCT 116 C172(1.09)  LDD0709  [11]
 LDCM0393  CL122 HCT 116 C172(0.95)  LDD0710  [11]
 LDCM0394  CL123 HCT 116 C172(1.07)  LDD0711  [11]
 LDCM0395  CL124 HCT 116 C172(1.19)  LDD0712  [11]
 LDCM0396  CL125 HCT 116 C172(1.12)  LDD0713  [11]
 LDCM0397  CL126 HCT 116 C172(1.04)  LDD0714  [11]
 LDCM0398  CL127 HCT 116 C172(1.11)  LDD0715  [11]
 LDCM0399  CL128 HCT 116 C172(1.22)  LDD0716  [11]
 LDCM0400  CL13 HCT 116 C172(1.18)  LDD0717  [11]
 LDCM0401  CL14 HCT 116 C172(1.23)  LDD0718  [11]
 LDCM0402  CL15 HCT 116 C172(1.37)  LDD0719  [11]
 LDCM0403  CL16 HCT 116 C172(1.02)  LDD0720  [11]
 LDCM0404  CL17 HCT 116 C172(1.30)  LDD0721  [11]
 LDCM0405  CL18 HCT 116 C172(0.87)  LDD0722  [11]
 LDCM0406  CL19 HCT 116 C172(0.86)  LDD0723  [11]
 LDCM0407  CL2 HCT 116 C172(1.02)  LDD0724  [11]
 LDCM0408  CL20 HCT 116 C172(0.95)  LDD0725  [11]
 LDCM0409  CL21 HCT 116 C172(1.16)  LDD0726  [11]
 LDCM0410  CL22 HCT 116 C172(1.46)  LDD0727  [11]
 LDCM0411  CL23 HCT 116 C172(1.00)  LDD0728  [11]
 LDCM0412  CL24 HCT 116 C172(1.54)  LDD0729  [11]
 LDCM0413  CL25 HCT 116 C172(1.33)  LDD0730  [11]
 LDCM0414  CL26 HCT 116 C172(1.21)  LDD0731  [11]
 LDCM0415  CL27 HCT 116 C172(1.04)  LDD0732  [11]
 LDCM0416  CL28 HCT 116 C172(1.08)  LDD0733  [11]
 LDCM0417  CL29 HCT 116 C172(1.05)  LDD0734  [11]
 LDCM0418  CL3 HCT 116 C172(0.95)  LDD0735  [11]
 LDCM0419  CL30 HCT 116 C172(0.98)  LDD0736  [11]
 LDCM0420  CL31 HCT 116 C172(0.87)  LDD0737  [11]
 LDCM0421  CL32 HCT 116 C172(1.00)  LDD0738  [11]
 LDCM0422  CL33 HCT 116 C172(1.28)  LDD0739  [11]
 LDCM0423  CL34 HCT 116 C172(0.88)  LDD0740  [11]
 LDCM0424  CL35 HCT 116 C172(0.98)  LDD0741  [11]
 LDCM0425  CL36 HCT 116 C172(1.01)  LDD0742  [11]
 LDCM0426  CL37 HCT 116 C172(0.92)  LDD0743  [11]
 LDCM0428  CL39 HCT 116 C172(1.09)  LDD0745  [11]
 LDCM0429  CL4 HCT 116 C172(0.93)  LDD0746  [11]
 LDCM0430  CL40 HCT 116 C172(1.17)  LDD0747  [11]
 LDCM0431  CL41 HCT 116 C172(0.98)  LDD0748  [11]
 LDCM0432  CL42 HCT 116 C172(0.94)  LDD0749  [11]
 LDCM0433  CL43 HCT 116 C172(0.96)  LDD0750  [11]
 LDCM0434  CL44 HCT 116 C172(1.01)  LDD0751  [11]
 LDCM0435  CL45 HCT 116 C172(1.07)  LDD0752  [11]
 LDCM0436  CL46 HCT 116 C172(1.06)  LDD0753  [11]
 LDCM0437  CL47 HCT 116 C172(0.91)  LDD0754  [11]
 LDCM0438  CL48 HCT 116 C172(0.90)  LDD0755  [11]
 LDCM0439  CL49 HCT 116 C172(0.99)  LDD0756  [11]
 LDCM0440  CL5 HCT 116 C172(0.87)  LDD0757  [11]
 LDCM0441  CL50 HCT 116 C172(0.98)  LDD0758  [11]
 LDCM0442  CL51 HCT 116 C172(1.08)  LDD0759  [11]
 LDCM0443  CL52 HCT 116 C172(1.09)  LDD0760  [11]
 LDCM0444  CL53 HCT 116 C172(0.93)  LDD0761  [11]
 LDCM0445  CL54 HCT 116 C172(0.92)  LDD0762  [11]
 LDCM0446  CL55 HCT 116 C172(0.86)  LDD0763  [11]
 LDCM0447  CL56 HCT 116 C172(0.98)  LDD0764  [11]
 LDCM0448  CL57 HCT 116 C172(0.90)  LDD0765  [11]
 LDCM0449  CL58 HCT 116 C172(0.92)  LDD0766  [11]
 LDCM0450  CL59 HCT 116 C172(0.89)  LDD0767  [11]
 LDCM0451  CL6 HCT 116 C172(1.72)  LDD0768  [11]
 LDCM0452  CL60 HCT 116 C172(1.01)  LDD0769  [11]
 LDCM0453  CL61 HCT 116 C172(1.09)  LDD0770  [11]
 LDCM0454  CL62 HCT 116 C172(1.25)  LDD0771  [11]
 LDCM0455  CL63 HCT 116 C172(1.33)  LDD0772  [11]
 LDCM0456  CL64 HCT 116 C172(1.24)  LDD0773  [11]
 LDCM0457  CL65 HCT 116 C172(1.06)  LDD0774  [11]
 LDCM0458  CL66 HCT 116 C172(1.10)  LDD0775  [11]
 LDCM0459  CL67 HCT 116 C172(0.94)  LDD0776  [11]
 LDCM0460  CL68 HCT 116 C172(1.08)  LDD0777  [11]
 LDCM0461  CL69 HCT 116 C172(1.27)  LDD0778  [11]
 LDCM0462  CL7 HCT 116 C172(1.01)  LDD0779  [11]
 LDCM0463  CL70 HCT 116 C172(0.97)  LDD0780  [11]
 LDCM0464  CL71 HCT 116 C172(1.23)  LDD0781  [11]
 LDCM0465  CL72 HCT 116 C172(1.25)  LDD0782  [11]
 LDCM0466  CL73 HCT 116 C172(1.23)  LDD0783  [11]
 LDCM0467  CL74 HCT 116 C172(1.14)  LDD0784  [11]
 LDCM0469  CL76 HCT 116 C172(0.90)  LDD0786  [11]
 LDCM0470  CL77 HCT 116 C172(1.16)  LDD0787  [11]
 LDCM0471  CL78 HCT 116 C172(1.02)  LDD0788  [11]
 LDCM0472  CL79 HCT 116 C172(0.95)  LDD0789  [11]
 LDCM0473  CL8 HCT 116 C172(3.24)  LDD0790  [11]
 LDCM0474  CL80 HCT 116 C172(0.94)  LDD0791  [11]
 LDCM0475  CL81 HCT 116 C172(0.91)  LDD0792  [11]
 LDCM0476  CL82 HCT 116 C172(0.84)  LDD0793  [11]
 LDCM0477  CL83 HCT 116 C172(1.03)  LDD0794  [11]
 LDCM0478  CL84 HCT 116 C172(1.00)  LDD0795  [11]
 LDCM0479  CL85 HCT 116 C172(0.96)  LDD0796  [11]
 LDCM0480  CL86 HCT 116 C172(0.83)  LDD0797  [11]
 LDCM0481  CL87 HCT 116 C172(0.93)  LDD0798  [11]
 LDCM0482  CL88 HCT 116 C172(0.85)  LDD0799  [11]
 LDCM0483  CL89 HCT 116 C172(0.86)  LDD0800  [11]
 LDCM0484  CL9 HCT 116 C172(1.15)  LDD0801  [11]
 LDCM0485  CL90 HCT 116 C172(1.24)  LDD0802  [11]
 LDCM0486  CL91 HCT 116 C172(0.93)  LDD0803  [11]
 LDCM0487  CL92 HCT 116 C172(1.02)  LDD0804  [11]
 LDCM0488  CL93 HCT 116 C172(0.98)  LDD0805  [11]
 LDCM0489  CL94 HCT 116 C172(1.01)  LDD0806  [11]
 LDCM0490  CL95 HCT 116 C172(1.72)  LDD0807  [11]
 LDCM0491  CL96 HCT 116 C172(0.96)  LDD0808  [11]
 LDCM0492  CL97 HCT 116 C172(0.93)  LDD0809  [11]
 LDCM0493  CL98 HCT 116 C172(1.14)  LDD0810  [11]
 LDCM0494  CL99 HCT 116 C172(1.11)  LDD0811  [11]
 LDCM0168  Crenolanib MV4-11 2.53  LDD0430  [23]
 LDCM0027  Dopamine HEK-293T 4.15  LDD0179  [8]
 LDCM0495  E2913 HEK-293T C172(0.93)  LDD1698  [25]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C172(0.96)  LDD1702  [7]
 LDCM0031  Epigallocatechin gallate HEK-293T 37.17  LDD0183  [8]
 LDCM0175  Ethacrynic acid HeLa N.A.  LDD0440  [10]
 LDCM0625  F8 Ramos C53(0.65)  LDD2187  [26]
 LDCM0572  Fragment10 MDA-MB-231 C172(20.00)  LDD1389  [27]
 LDCM0573  Fragment11 Ramos C172(3.35)  LDD1392  [27]
 LDCM0574  Fragment12 MDA-MB-231 C172(0.94)  LDD1468  [27]
 LDCM0575  Fragment13 MDA-MB-231 C172(0.64)  LDD1395  [27]
 LDCM0576  Fragment14 MDA-MB-231 C172(0.40)  LDD1397  [27]
 LDCM0577  Fragment15 Ramos C172(0.86)  LDD1400  [27]
 LDCM0579  Fragment20 MDA-MB-231 C172(3.24)  LDD1402  [27]
 LDCM0580  Fragment21 MDA-MB-231 C172(1.41)  LDD1404  [27]
 LDCM0582  Fragment23 MDA-MB-231 C172(0.93)  LDD1408  [27]
 LDCM0584  Fragment25 MDA-MB-231 C172(0.87)  LDD1411  [27]
 LDCM0578  Fragment27 MDA-MB-231 C172(0.56)  LDD1401  [27]
 LDCM0587  Fragment29 MDA-MB-231 C172(0.76)  LDD1417  [27]
 LDCM0588  Fragment30 Ramos C172(1.68)  LDD1420  [27]
 LDCM0589  Fragment31 Ramos C172(0.96)  LDD1422  [27]
 LDCM0590  Fragment32 Ramos C172(1.42)  LDD1424  [27]
 LDCM0468  Fragment33 HCT 116 C172(1.21)  LDD0785  [11]
 LDCM0592  Fragment34 Ramos C172(1.79)  LDD1428  [27]
 LDCM0593  Fragment35 Ramos C172(0.63)  LDD1430  [27]
 LDCM0596  Fragment38 MDA-MB-231 C172(0.99)  LDD1433  [27]
 LDCM0566  Fragment4 MDA-MB-231 C172(5.26)  LDD1461  [27]
 LDCM0598  Fragment40 Ramos C172(0.99)  LDD1437  [27]
 LDCM0599  Fragment41 MDA-MB-231 C172(1.22)  LDD1438  [27]
 LDCM0600  Fragment42 Ramos C172(1.14)  LDD1440  [27]
 LDCM0602  Fragment44 MDA-MB-231 C172(0.37)  LDD1443  [27]
 LDCM0604  Fragment46 MDA-MB-231 C172(0.81)  LDD1445  [27]
 LDCM0605  Fragment47 MDA-MB-231 C172(0.89)  LDD1446  [27]
 LDCM0607  Fragment49 MDA-MB-231 C172(1.02)  LDD1448  [27]
 LDCM0608  Fragment50 MDA-MB-231 C172(3.78)  LDD1449  [27]
 LDCM0427  Fragment51 HCT 116 C172(0.93)  LDD0744  [11]
 LDCM0610  Fragment52 MDA-MB-231 C172(0.52)  LDD1452  [27]
 LDCM0569  Fragment7 MDA-MB-231 C172(0.51)  LDD1383  [27]
 LDCM0570  Fragment8 MDA-MB-231 C172(20.00)  LDD1385  [27]
 LDCM0571  Fragment9 MDA-MB-231 C172(1.17)  LDD1387  [27]
 LDCM0022  KB02 HCT 116 C172(3.26)  LDD0080  [11]
 LDCM0023  KB03 HCT 116 C172(1.12)  LDD0081  [11]
 LDCM0024  KB05 HCT 116 C172(1.17)  LDD0082  [11]
 LDCM0030  Luteolin HEK-293T 12.41  LDD0182  [8]
 LDCM0109  NEM HeLa N.A.  LDD0223  [20]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C172(1.12)  LDD2089  [7]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C172(1.09)  LDD2099  [7]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C172(0.89)  LDD2105  [7]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C172(1.03)  LDD2107  [7]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C172(0.75)  LDD2114  [7]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C172(1.44)  LDD2119  [7]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C172(0.86)  LDD2120  [7]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C172(0.80)  LDD2123  [7]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C172(1.00)  LDD2125  [7]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C172(1.08)  LDD2127  [7]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C172(1.24)  LDD2129  [7]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C172(0.34)  LDD2134  [7]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C172(1.14)  LDD2135  [7]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C172(1.03)  LDD2136  [7]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C172(1.00)  LDD2140  [7]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C172(1.10)  LDD2141  [7]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C172(1.32)  LDD2143  [7]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C172(1.11)  LDD2146  [7]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C172(0.83)  LDD2150  [7]
 LDCM0029  Quercetin HEK-293T 8.54  LDD0181  [8]
 LDCM0131  RA190 MM1.R C172(1.35); C53(1.29)  LDD0304  [28]
 LDCM0021  THZ1 HCT 116 C172(1.13)  LDD2173  [11]

References

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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD043348
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD036569
18 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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