Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name CR-1  Probe Info 
Probe concentration 1 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Crenolanib  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Acute monocytic leukemia [ICD-11:2A60]
Model Name Human acute monocytic leukemia cells (MV4-11)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02783  Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) 3.7
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14014  Chromatin target of PRMT1 protein (CHTOP) 3.1
 LDTP04931  10 kDa heat shock protein, mitochondrial (HSPE1) 2.9
 LDTP11179  LIM domain-containing protein 2 (LIMD2) 2.8
 LDTP15701  EF-hand domain-containing protein D2 (EFHD2) 2.5

References

1 Crenolanib-Derived Probes Suitable for Cell- and Tissue-Based Protein Profiling and Single-Cell Imaging. Chembiochem. 2019 Jul 15;20(14):1783-1788. doi: 10.1002/cbic.201900067. Epub 2019 Jul 3.