Details of the Target

General Information of Target

Target ID LDTP11179
Target Name LIM domain-containing protein 2 (LIMD2)
Gene Name LIMD2
Gene ID 80774
Synonyms
LIM domain-containing protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAASCLVLLALCLLLPLLLLGGWKRWRRGRAARHVVAVVLGDVGRSPRMQYHALSLAMHG
FSVTLLGFCNSKPHDELLQNNRIQIVGLTELQSLAVGPRVFQYGVKVVLQAMYLLWKLMW
REPGAYIFLQNPPGLPSIAVCWFVGCLCGSKLVIDWHNYGYSIMGLVHGPNHPLVLLAKW
YEKFFGRLSHLNLCVTNAMREDLADNWHIRAVTVYDKPASFFKETPLDLQHRLFMKLGSM
HSPFRARSEPEDPVTERSAFTERDAGSGLVTRLRERPALLVSSTSWTEDEDFSILLAALE
KFEQLTLDGHNLPSLVCVITGKGPLREYYSRLIHQKHFQHIQVCTPWLEAEDYPLLLGSA
DLGVCLHTSSSGLDLPMKVVDMFGCCLPVCAVNFKCLHELVKHEENGLVFEDSEELAAQL
QMLFSNFPDPAGKLNQFRKNLRESQQLRWDESWVQTVLPLVMDT
Target Bioclass
Other
Subcellular location
Cytoplasm
Function Acts as an activator of the protein-kinase ILK, thereby regulating cell motility.
Uniprot ID
Q9BT23
Ensemble ID
ENST00000259006.8
HGNC ID
HGNC:28142

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K99(3.56)  LDD2218  [1]
IA-alkyne
 Probe Info  		0.78  LDD2182  [2]
DBIA
 Probe Info  		C40(1.07); C43(1.07)  LDD0078  [3]
HHS-465
 Probe Info  		N.A.  LDD2240  [4]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CR-1
 Probe Info  		2.76  LDD0430  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C40(0.75)  LDD0812  [3]
 LDCM0215  AC10 HEK-293T C40(1.12); C43(1.12)  LDD0813  [3]
 LDCM0226  AC11 HEK-293T C40(1.13); C43(1.13)  LDD0824  [3]
 LDCM0230  AC113 HEK-293T C40(0.68)  LDD0828  [3]
 LDCM0231  AC114 HEK-293T C40(0.79)  LDD0829  [3]
 LDCM0232  AC115 HEK-293T C40(0.82)  LDD0830  [3]
 LDCM0233  AC116 HEK-293T C40(0.69)  LDD0831  [3]
 LDCM0234  AC117 HEK-293T C40(0.71)  LDD0832  [3]
 LDCM0235  AC118 HEK-293T C40(0.73)  LDD0833  [3]
 LDCM0236  AC119 HEK-293T C40(0.71)  LDD0834  [3]
 LDCM0237  AC12 HEK-293T C40(1.09); C43(1.09)  LDD0835  [3]
 LDCM0238  AC120 HEK-293T C40(0.88)  LDD0836  [3]
 LDCM0239  AC121 HEK-293T C40(0.59)  LDD0837  [3]
 LDCM0240  AC122 HEK-293T C40(0.60)  LDD0838  [3]
 LDCM0241  AC123 HEK-293T C40(0.78)  LDD0839  [3]
 LDCM0242  AC124 HEK-293T C40(0.78)  LDD0840  [3]
 LDCM0243  AC125 HEK-293T C40(0.61)  LDD0841  [3]
 LDCM0244  AC126 HEK-293T C40(0.56)  LDD0842  [3]
 LDCM0245  AC127 HEK-293T C40(0.77)  LDD0843  [3]
 LDCM0246  AC128 HEK-293T C40(0.77)  LDD0844  [3]
 LDCM0247  AC129 HEK-293T C40(0.74)  LDD0845  [3]
 LDCM0249  AC130 HEK-293T C40(0.70)  LDD0847  [3]
 LDCM0250  AC131 HEK-293T C40(0.69)  LDD0848  [3]
 LDCM0251  AC132 HEK-293T C40(0.82)  LDD0849  [3]
 LDCM0252  AC133 HEK-293T C40(0.73)  LDD0850  [3]
 LDCM0253  AC134 HEK-293T C40(0.63)  LDD0851  [3]
 LDCM0254  AC135 HEK-293T C40(0.96)  LDD0852  [3]
 LDCM0255  AC136 HEK-293T C40(0.66)  LDD0853  [3]
 LDCM0256  AC137 HEK-293T C40(0.52)  LDD0854  [3]
 LDCM0257  AC138 HEK-293T C40(0.57)  LDD0855  [3]
 LDCM0258  AC139 HEK-293T C40(0.56)  LDD0856  [3]
 LDCM0259  AC14 HEK-293T C40(1.43); C43(1.43)  LDD0857  [3]
 LDCM0260  AC140 HEK-293T C40(0.60)  LDD0858  [3]
 LDCM0261  AC141 HEK-293T C40(0.55)  LDD0859  [3]
 LDCM0262  AC142 HEK-293T C40(0.58)  LDD0860  [3]
 LDCM0263  AC143 HEK-293T C40(0.94)  LDD0861  [3]
 LDCM0264  AC144 HEK-293T C40(0.64)  LDD0862  [3]
 LDCM0265  AC145 HEK-293T C40(0.67)  LDD0863  [3]
 LDCM0266  AC146 HEK-293T C40(0.69)  LDD0864  [3]
 LDCM0267  AC147 HEK-293T C40(0.69)  LDD0865  [3]
 LDCM0268  AC148 HEK-293T C40(0.95)  LDD0866  [3]
 LDCM0269  AC149 HEK-293T C40(1.27)  LDD0867  [3]
 LDCM0270  AC15 HEK-293T C40(1.36); C43(1.36)  LDD0868  [3]
 LDCM0271  AC150 HEK-293T C40(0.90)  LDD0869  [3]
 LDCM0272  AC151 HEK-293T C40(0.81)  LDD0870  [3]
 LDCM0273  AC152 HEK-293T C40(0.95)  LDD0871  [3]
 LDCM0274  AC153 HEK-293T C40(0.79)  LDD0872  [3]
 LDCM0621  AC154 HEK-293T C40(0.90)  LDD2162  [3]
 LDCM0622  AC155 HEK-293T C40(0.89)  LDD2163  [3]
 LDCM0623  AC156 HEK-293T C40(0.76)  LDD2164  [3]
 LDCM0624  AC157 HEK-293T C40(0.66)  LDD2165  [3]
 LDCM0276  AC17 HEK-293T C40(0.80); C43(0.95)  LDD0874  [3]
 LDCM0277  AC18 HEK-293T C40(0.86); C43(0.88)  LDD0875  [3]
 LDCM0278  AC19 HEK-293T C40(0.74); C43(0.83)  LDD0876  [3]
 LDCM0279  AC2 HEK-293T C40(1.17)  LDD0877  [3]
 LDCM0280  AC20 HEK-293T C40(0.81); C43(0.74)  LDD0878  [3]
 LDCM0281  AC21 HEK-293T C40(0.88); C43(0.79)  LDD0879  [3]
 LDCM0282  AC22 HEK-293T C40(0.82); C43(0.84)  LDD0880  [3]
 LDCM0283  AC23 HEK-293T C40(0.97); C43(0.91)  LDD0881  [3]
 LDCM0284  AC24 HEK-293T C40(1.02); C43(1.00)  LDD0882  [3]
 LDCM0285  AC25 HEK-293T C40(1.10)  LDD0883  [3]
 LDCM0286  AC26 HEK-293T C40(1.16)  LDD0884  [3]
 LDCM0287  AC27 HEK-293T C40(1.21)  LDD0885  [3]
 LDCM0288  AC28 HEK-293T C40(1.89)  LDD0886  [3]
 LDCM0289  AC29 HEK-293T C40(1.34)  LDD0887  [3]
 LDCM0290  AC3 HEK-293T C40(0.96)  LDD0888  [3]
 LDCM0291  AC30 HEK-293T C40(1.30)  LDD0889  [3]
 LDCM0292  AC31 HEK-293T C40(1.28)  LDD0890  [3]
 LDCM0293  AC32 HEK-293T C40(1.28)  LDD0891  [3]
 LDCM0294  AC33 HEK-293T C40(1.21)  LDD0892  [3]
 LDCM0295  AC34 HEK-293T C40(1.11)  LDD0893  [3]
 LDCM0296  AC35 HEK-293T C40(1.03); C43(0.92)  LDD0894  [3]
 LDCM0297  AC36 HEK-293T C40(1.07); C43(1.03)  LDD0895  [3]
 LDCM0298  AC37 HEK-293T C40(1.11); C43(1.03)  LDD0896  [3]
 LDCM0299  AC38 HEK-293T C40(1.20); C43(1.20)  LDD0897  [3]
 LDCM0300  AC39 HEK-293T C40(1.07); C43(0.86)  LDD0898  [3]
 LDCM0301  AC4 HEK-293T C40(0.80)  LDD0899  [3]
 LDCM0302  AC40 HEK-293T C40(0.94); C43(1.03)  LDD0900  [3]
 LDCM0303  AC41 HEK-293T C40(1.19); C43(1.21)  LDD0901  [3]
 LDCM0304  AC42 HEK-293T C40(0.98); C43(0.94)  LDD0902  [3]
 LDCM0305  AC43 HEK-293T C40(1.10); C43(1.12)  LDD0903  [3]
 LDCM0306  AC44 HEK-293T C40(1.15); C43(1.14)  LDD0904  [3]
 LDCM0307  AC45 HEK-293T C40(1.34); C43(1.23)  LDD0905  [3]
 LDCM0308  AC46 HEK-293T C40(1.52); C43(1.52)  LDD0906  [3]
 LDCM0309  AC47 HEK-293T C40(1.16); C43(1.16)  LDD0907  [3]
 LDCM0310  AC48 HEK-293T C40(1.92); C43(1.92)  LDD0908  [3]
 LDCM0311  AC49 HEK-293T C40(1.53); C43(1.53)  LDD0909  [3]
 LDCM0312  AC5 HEK-293T C40(1.00)  LDD0910  [3]
 LDCM0313  AC50 HEK-293T C40(1.31); C43(1.31)  LDD0911  [3]
 LDCM0314  AC51 HEK-293T C40(1.21); C43(1.21)  LDD0912  [3]
 LDCM0315  AC52 HEK-293T C40(1.16); C43(1.16)  LDD0913  [3]
 LDCM0316  AC53 HEK-293T C40(1.42); C43(1.42)  LDD0914  [3]
 LDCM0317  AC54 HEK-293T C40(1.55); C43(1.55)  LDD0915  [3]
 LDCM0318  AC55 HEK-293T C40(1.29); C43(1.29)  LDD0916  [3]
 LDCM0319  AC56 HEK-293T C40(1.62); C43(1.62)  LDD0917  [3]
 LDCM0320  AC57 HEK-293T C40(0.79)  LDD0918  [3]
 LDCM0321  AC58 HEK-293T C40(0.84)  LDD0919  [3]
 LDCM0322  AC59 HEK-293T C40(0.92)  LDD0920  [3]
 LDCM0323  AC6 HEK-293T C40(1.04); C43(1.04)  LDD0921  [3]
 LDCM0324  AC60 HEK-293T C40(0.54)  LDD0922  [3]
 LDCM0325  AC61 HEK-293T C40(0.80)  LDD0923  [3]
 LDCM0326  AC62 HEK-293T C40(0.77)  LDD0924  [3]
 LDCM0327  AC63 HEK-293T C40(0.66)  LDD0925  [3]
 LDCM0328  AC64 HEK-293T C40(0.84)  LDD0926  [3]
 LDCM0329  AC65 HEK-293T C40(1.08)  LDD0927  [3]
 LDCM0330  AC66 HEK-293T C40(0.71)  LDD0928  [3]
 LDCM0331  AC67 HEK-293T C40(0.67)  LDD0929  [3]
 LDCM0332  AC68 HEK-293T C40(0.91)  LDD0930  [3]
 LDCM0333  AC69 HEK-293T C40(1.06)  LDD0931  [3]
 LDCM0334  AC7 HEK-293T C40(1.06); C43(1.06)  LDD0932  [3]
 LDCM0335  AC70 HEK-293T C40(1.12)  LDD0933  [3]
 LDCM0336  AC71 HEK-293T C40(1.07)  LDD0934  [3]
 LDCM0337  AC72 HEK-293T C40(1.37)  LDD0935  [3]
 LDCM0338  AC73 HEK-293T C40(1.12)  LDD0936  [3]
 LDCM0339  AC74 HEK-293T C40(1.13)  LDD0937  [3]
 LDCM0340  AC75 HEK-293T C40(1.17)  LDD0938  [3]
 LDCM0341  AC76 HEK-293T C40(1.14)  LDD0939  [3]
 LDCM0342  AC77 HEK-293T C40(1.37)  LDD0940  [3]
 LDCM0343  AC78 HEK-293T C40(0.99)  LDD0941  [3]
 LDCM0344  AC79 HEK-293T C40(1.05)  LDD0942  [3]
 LDCM0345  AC8 HEK-293T C40(0.96); C43(0.96)  LDD0943  [3]
 LDCM0346  AC80 HEK-293T C40(1.16)  LDD0944  [3]
 LDCM0347  AC81 HEK-293T C40(1.02)  LDD0945  [3]
 LDCM0348  AC82 HEK-293T C40(0.86)  LDD0946  [3]
 LDCM0349  AC83 HEK-293T C40(0.96)  LDD0947  [3]
 LDCM0350  AC84 HEK-293T C40(1.01)  LDD0948  [3]
 LDCM0351  AC85 HEK-293T C40(1.11)  LDD0949  [3]
 LDCM0352  AC86 HEK-293T C40(1.17)  LDD0950  [3]
 LDCM0353  AC87 HEK-293T C40(0.84)  LDD0951  [3]
 LDCM0354  AC88 HEK-293T C40(0.89)  LDD0952  [3]
 LDCM0355  AC89 HEK-293T C40(1.06)  LDD0953  [3]
 LDCM0357  AC90 HEK-293T C40(0.98)  LDD0955  [3]
 LDCM0358  AC91 HEK-293T C40(1.06)  LDD0956  [3]
 LDCM0359  AC92 HEK-293T C40(1.05)  LDD0957  [3]
 LDCM0360  AC93 HEK-293T C40(1.01)  LDD0958  [3]
 LDCM0361  AC94 HEK-293T C40(0.90)  LDD0959  [3]
 LDCM0362  AC95 HEK-293T C40(1.07)  LDD0960  [3]
 LDCM0363  AC96 HEK-293T C40(1.15)  LDD0961  [3]
 LDCM0364  AC97 HEK-293T C40(0.76)  LDD0962  [3]
 LDCM0248  AKOS034007472 HEK-293T C40(1.13); C43(1.13)  LDD0846  [3]
 LDCM0356  AKOS034007680 HEK-293T C40(1.35); C43(1.35)  LDD0954  [3]
 LDCM0275  AKOS034007705 HEK-293T C40(1.30); C43(1.30)  LDD0873  [3]
 LDCM0020  ARS-1620 HCC44 C40(1.07); C43(1.07)  LDD0078  [3]
 LDCM0369  CL100 HEK-293T C40(1.39)  LDD0967  [3]
 LDCM0370  CL101 HEK-293T C40(0.84); C43(0.84)  LDD0968  [3]
 LDCM0371  CL102 HEK-293T C40(0.90); C43(0.90)  LDD0969  [3]
 LDCM0372  CL103 HEK-293T C40(0.95); C43(0.95)  LDD0970  [3]
 LDCM0373  CL104 HEK-293T C40(0.97); C43(0.97)  LDD0971  [3]
 LDCM0374  CL105 HEK-293T C40(0.77); C43(0.80)  LDD0972  [3]
 LDCM0375  CL106 HEK-293T C40(0.89); C43(0.81)  LDD0973  [3]
 LDCM0376  CL107 HEK-293T C40(0.84); C43(1.08)  LDD0974  [3]
 LDCM0377  CL108 HEK-293T C40(0.73); C43(0.93)  LDD0975  [3]
 LDCM0378  CL109 HEK-293T C40(0.84); C43(0.92)  LDD0976  [3]
 LDCM0380  CL110 HEK-293T C40(0.76); C43(0.76)  LDD0978  [3]
 LDCM0381  CL111 HEK-293T C40(1.00); C43(1.02)  LDD0979  [3]
 LDCM0382  CL112 HEK-293T C40(1.12)  LDD0980  [3]
 LDCM0383  CL113 HEK-293T C40(0.96)  LDD0981  [3]
 LDCM0384  CL114 HEK-293T C40(1.15)  LDD0982  [3]
 LDCM0385  CL115 HEK-293T C40(1.00)  LDD0983  [3]
 LDCM0386  CL116 HEK-293T C40(1.04)  LDD0984  [3]
 LDCM0387  CL117 HEK-293T C40(1.21); C43(1.15)  LDD0985  [3]
 LDCM0388  CL118 HEK-293T C40(1.09); C43(1.19)  LDD0986  [3]
 LDCM0389  CL119 HEK-293T C40(1.10); C43(1.29)  LDD0987  [3]
 LDCM0391  CL120 HEK-293T C40(1.10); C43(1.06)  LDD0989  [3]
 LDCM0392  CL121 HEK-293T C40(1.19); C43(1.19)  LDD0990  [3]
 LDCM0393  CL122 HEK-293T C40(1.06); C43(1.06)  LDD0991  [3]
 LDCM0394  CL123 HEK-293T C40(1.19); C43(1.19)  LDD0992  [3]
 LDCM0395  CL124 HEK-293T C40(1.36); C43(1.36)  LDD0993  [3]
 LDCM0396  CL125 HEK-293T C40(0.86)  LDD0994  [3]
 LDCM0397  CL126 HEK-293T C40(0.76)  LDD0995  [3]
 LDCM0398  CL127 HEK-293T C40(0.86)  LDD0996  [3]
 LDCM0399  CL128 HEK-293T C40(0.49)  LDD0997  [3]
 LDCM0403  CL16 HEK-293T C40(1.09); C43(1.09)  LDD1001  [3]
 LDCM0404  CL17 HEK-293T C40(1.15); C43(1.03)  LDD1002  [3]
 LDCM0405  CL18 HEK-293T C40(0.94); C43(0.92)  LDD1003  [3]
 LDCM0406  CL19 HEK-293T C40(1.01); C43(1.03)  LDD1004  [3]
 LDCM0408  CL20 HEK-293T C40(1.16); C43(0.97)  LDD1006  [3]
 LDCM0409  CL21 HEK-293T C40(0.94); C43(0.87)  LDD1007  [3]
 LDCM0410  CL22 HEK-293T C40(0.90); C43(0.99)  LDD1008  [3]
 LDCM0411  CL23 HEK-293T C40(0.94); C43(1.06)  LDD1009  [3]
 LDCM0412  CL24 HEK-293T C40(1.15); C43(1.07)  LDD1010  [3]
 LDCM0413  CL25 HEK-293T C40(1.12); C43(0.99)  LDD1011  [3]
 LDCM0414  CL26 HEK-293T C40(1.14); C43(1.17)  LDD1012  [3]
 LDCM0415  CL27 HEK-293T C40(1.00); C43(1.21)  LDD1013  [3]
 LDCM0416  CL28 HEK-293T C40(1.14); C43(1.16)  LDD1014  [3]
 LDCM0417  CL29 HEK-293T C40(1.15); C43(1.12)  LDD1015  [3]
 LDCM0419  CL30 HEK-293T C40(1.04); C43(1.12)  LDD1017  [3]
 LDCM0420  CL31 HEK-293T C40(1.01); C43(1.24)  LDD1018  [3]
 LDCM0421  CL32 HEK-293T C40(1.11); C43(1.10)  LDD1019  [3]
 LDCM0422  CL33 HEK-293T C40(0.70); C43(0.68)  LDD1020  [3]
 LDCM0423  CL34 HEK-293T C40(1.02); C43(0.99)  LDD1021  [3]
 LDCM0424  CL35 HEK-293T C40(1.09); C43(1.05)  LDD1022  [3]
 LDCM0425  CL36 HEK-293T C40(0.95); C43(0.95)  LDD1023  [3]
 LDCM0426  CL37 HEK-293T C40(1.07); C43(1.20)  LDD1024  [3]
 LDCM0428  CL39 HEK-293T C40(0.87); C43(0.69)  LDD1026  [3]
 LDCM0430  CL40 HEK-293T C40(0.91); C43(0.90)  LDD1028  [3]
 LDCM0431  CL41 HEK-293T C40(1.23); C43(0.96)  LDD1029  [3]
 LDCM0432  CL42 HEK-293T C40(0.97); C43(0.81)  LDD1030  [3]
 LDCM0433  CL43 HEK-293T C40(1.10); C43(0.89)  LDD1031  [3]
 LDCM0434  CL44 HEK-293T C40(1.20); C43(1.17)  LDD1032  [3]
 LDCM0435  CL45 HEK-293T C40(0.86); C43(0.76)  LDD1033  [3]
 LDCM0436  CL46 HEK-293T C43(1.08)  LDD1034  [3]
 LDCM0437  CL47 HEK-293T C43(1.28)  LDD1035  [3]
 LDCM0438  CL48 HEK-293T C43(1.36)  LDD1036  [3]
 LDCM0439  CL49 HEK-293T C43(1.17)  LDD1037  [3]
 LDCM0441  CL50 HEK-293T C43(0.69)  LDD1039  [3]
 LDCM0442  CL51 HEK-293T C43(0.93)  LDD1040  [3]
 LDCM0443  CL52 HEK-293T C43(1.27)  LDD1041  [3]
 LDCM0444  CL53 HEK-293T C43(1.10)  LDD1042  [3]
 LDCM0445  CL54 HEK-293T C43(1.25)  LDD1043  [3]
 LDCM0446  CL55 HEK-293T C43(1.17)  LDD1044  [3]
 LDCM0447  CL56 HEK-293T C43(1.18)  LDD1045  [3]
 LDCM0448  CL57 HEK-293T C43(1.24)  LDD1046  [3]
 LDCM0449  CL58 HEK-293T C43(0.98)  LDD1047  [3]
 LDCM0450  CL59 HEK-293T C43(0.82)  LDD1048  [3]
 LDCM0452  CL60 HEK-293T C43(0.91)  LDD1050  [3]
 LDCM0469  CL76 HEK-293T C40(0.93); C43(0.93)  LDD1067  [3]
 LDCM0470  CL77 HEK-293T C40(0.67); C43(0.67)  LDD1068  [3]
 LDCM0471  CL78 HEK-293T C40(0.99); C43(0.99)  LDD1069  [3]
 LDCM0472  CL79 HEK-293T C40(0.81); C43(0.81)  LDD1070  [3]
 LDCM0474  CL80 HEK-293T C40(0.99); C43(0.99)  LDD1072  [3]
 LDCM0475  CL81 HEK-293T C40(0.99); C43(0.99)  LDD1073  [3]
 LDCM0476  CL82 HEK-293T C40(0.98); C43(0.98)  LDD1074  [3]
 LDCM0477  CL83 HEK-293T C40(0.97); C43(0.97)  LDD1075  [3]
 LDCM0478  CL84 HEK-293T C40(0.97); C43(0.97)  LDD1076  [3]
 LDCM0479  CL85 HEK-293T C40(1.08); C43(1.08)  LDD1077  [3]
 LDCM0480  CL86 HEK-293T C40(0.82); C43(0.82)  LDD1078  [3]
 LDCM0481  CL87 HEK-293T C40(0.98); C43(0.98)  LDD1079  [3]
 LDCM0482  CL88 HEK-293T C40(1.10); C43(1.10)  LDD1080  [3]
 LDCM0483  CL89 HEK-293T C40(1.12); C43(1.12)  LDD1081  [3]
 LDCM0485  CL90 HEK-293T C40(0.87); C43(0.87)  LDD1083  [3]
 LDCM0486  CL91 HEK-293T C40(1.01)  LDD1084  [3]
 LDCM0487  CL92 HEK-293T C40(0.88)  LDD1085  [3]
 LDCM0488  CL93 HEK-293T C40(0.83)  LDD1086  [3]
 LDCM0489  CL94 HEK-293T C40(0.71)  LDD1087  [3]
 LDCM0490  CL95 HEK-293T C40(0.80)  LDD1088  [3]
 LDCM0491  CL96 HEK-293T C40(0.97)  LDD1089  [3]
 LDCM0492  CL97 HEK-293T C40(1.19)  LDD1090  [3]
 LDCM0493  CL98 HEK-293T C40(0.88)  LDD1091  [3]
 LDCM0494  CL99 HEK-293T C40(1.07)  LDD1092  [3]
 LDCM0168  Crenolanib MV4-11 2.76  LDD0430  [5]
 LDCM0625  F8 Ramos 1.17  LDD2187  [2]
 LDCM0572  Fragment10 Ramos 0.58  LDD2189  [2]
 LDCM0573  Fragment11 Ramos 4.19  LDD2190  [2]
 LDCM0574  Fragment12 Ramos 0.77  LDD2191  [2]
 LDCM0575  Fragment13 Ramos 1.38  LDD2192  [2]
 LDCM0576  Fragment14 Ramos 1.83  LDD2193  [2]
 LDCM0579  Fragment20 Ramos 0.57  LDD2194  [2]
 LDCM0580  Fragment21 Ramos 0.93  LDD2195  [2]
 LDCM0582  Fragment23 Ramos 0.93  LDD2196  [2]
 LDCM0578  Fragment27 Ramos 1.07  LDD2197  [2]
 LDCM0586  Fragment28 Ramos 0.84  LDD2198  [2]
 LDCM0588  Fragment30 Ramos 0.90  LDD2199  [2]
 LDCM0589  Fragment31 Ramos 1.23  LDD2200  [2]
 LDCM0590  Fragment32 Ramos 0.77  LDD2201  [2]
 LDCM0468  Fragment33 Ramos 0.96  LDD2202  [2]
 LDCM0596  Fragment38 Ramos 1.15  LDD2203  [2]
 LDCM0566  Fragment4 Ramos 0.82  LDD2184  [2]
 LDCM0427  Fragment51 HEK-293T C40(1.19); C43(1.05)  LDD1025  [3]
 LDCM0610  Fragment52 Ramos 1.31  LDD2204  [2]
 LDCM0614  Fragment56 Ramos 2.17  LDD2205  [2]
 LDCM0569  Fragment7 Ramos 0.81  LDD2186  [2]
 LDCM0571  Fragment9 Ramos 0.71  LDD2188  [2]
 LDCM0022  KB02 HCT 116 C40(1.65); C43(1.65)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C40(1.67); C43(1.67)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C40(1.90); C43(1.90)  LDD0082  [3]
 LDCM0021  THZ1 HCT 116 C40(1.46); C43(1.46)  LDD2173  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Proteasome subunit alpha type-6 (PSMA6) Peptidase T1A family P60900

References

1 Global profiling of lysine reactivity and ligandability in the human proteome. Nat Chem. 2017 Dec;9(12):1181-1190. doi: 10.1038/nchem.2826. Epub 2017 Jul 31.
2 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
5 Crenolanib-Derived Probes Suitable for Cell- and Tissue-Based Protein Profiling and Single-Cell Imaging. Chembiochem. 2019 Jul 15;20(14):1783-1788. doi: 10.1002/cbic.201900067. Epub 2019 Jul 3.