Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0031
Competitor Name
Epigallocatechin gallate
Synonyms
(-)-Epigallocatechin gallate; EGCG; 989-51-5; Epigallocatechin gallate; Epigallocatechin 3-gallate; Tea catechin; Epigallocatechin-3-gallate; Teavigo; Epigallocatechin-3-monogallate; (-)-Epigallocatechin-3-o-gallate; (-)-epigallocatechin 3-gallate; PF-EGCg 90; (-)-Epigallocatechol gallate; NVP-XAA 723; CCRIS 3729; (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate; Catechin deriv.; UNII-BQM438CTEL; BQM438CTEL; epigallocatechin-3-O-gallate; CHEBI:4806; Epigallocatechingallate; Epigallocatechin-gallate; Epigallocatechol, 3-gallate, (-)-; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate; CHEMBL297453; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate; DTXSID1029889; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate; Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester; EGCG cpd; (-)-Epigallocatechin Gallate (Standard); (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate; Gallic acid, 3-ester with epigallocatechol, (-)-; DTXCID80567; (-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate; epigallo-catechin gallate; (-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate; Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R-cis)-; Benzoic acid, 3,4,5-trihydroxy-,(2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester; CAS-989-51-5; SMR000449288; SR-01000759328; (-)-EPIGALLOCATECHIN-3-O-GALLATE (USP-RS); (-)-EPIGALLOCATECHIN-3-O-GALLATE [USP-RS]; L-Epigallocatechin gallate; Epigallocate; Sunphenon; EPIGALOCATECHIN GALLATE; (-)-EGCG; Epigallocic acid; Teatannin II; 2kdh; 3oob; 4awm; (-)-epigallocatechin 3-O-gallate; KDH; Epigallocatcchin Gallate; Epigallocatechol Gallate; Spectrum_000316; SpecPlus_000277; Spectrum2_000168; Spectrum3_000244; Spectrum4_001541; Spectrum5_000102; Galloyl-L-epigallocatechol; EGCG [WHO-DD]; EGCG [MI]; 3-O-Galloylepigallocatechin; (-)-Epigallocatechin gallat; (-)-Epigallocatehin gallate; SCHEMBL35258; BSPBio_001628; epigallocatechin-gallate-(-); KBioGR_002002; KBioSS_000796; SPECTRUM210239; cid_65064; MLS000758300; MLS001424000; DivK1c_006373; SPBio_000035; Epigallocatechin monogallate, B; GTPL7002; MEGxp0_001166; (-)-Epigallocatechin-3-gallate; ACon1_001054; KBio1_001317; KBio2_000796; KBio2_003364; KBio2_005932; KBio3_001128; HMS2051K21; HMS3649E08; 3-O-Galloyl-(-)-epigallocatechin; EPIGALLOCATECHIN 3-O-GALLATE; Tox21_201468; Tox21_303457; BDBM50070942; CCG-38378; FR-109; HY-13653R; LMPK12030005; MFCD00075940; s2250; AKOS015918182; CS-1258; DB12116; DS-9030; EPIGALLOCATECHIN GALLATE [INCI]; MCULE-3341525983; MCULE-7760530136; NC00078; SDCCGMLS-0066550.P001; (-)-Epigallocatechin gallate, >=95%; (-)-Epigallocatechin-3-gallate; EGCG; NCGC00164319-01; NCGC00164319-02; NCGC00164319-03; NCGC00164319-04; NCGC00164319-06; NCGC00257243-01; NCGC00259019-01; (-)-Epigallocatechin gallate (85% (-)-epigallocatechin gallate, 10% (-)-epigallocatechin, 5% (-)- epicatechin gallate); 1ST40118; AC-34075; BP-30205; HY-13653; CS-0694875; E0694; NS00015163; SW197458-3; C09731; M01719; (-)-Epigallocatechin gallate, >=97.0% (HPLC); (-)-Epigallocatechin gallate, analytical standard; A845931; Q393339; SR-01000946601; Q-100914; SR-01000759328-5; SR-01000759328-6; SR-01000946601-1; Epigallocatechin-3-gallate 1000 microg/mL in Acetonitrile; (-)-Epigallocatechin gallate, >=80% (HPLC), from green tea; Epigallocatechin gallate, primary pharmaceutical reference standard; ((2R,3R)-2-(3,4,5-trihydroxyphenyl)-5,7-dihydroxy-chroman-3-yl) 3,4,5-trihydroxybenzoate; (-)-Epigallocatechin-3-O-gallate, United States Pharmacopeia (USP) Reference Standard; (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl3,4,5-trihydroxybenzoate; [5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 2,3,4-trihydroxybenzoate; Epigallocatechin gallate, Pharmaceutical Secondary Standard; Certified Reference Material; (-)-cis-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-1(2H)-benzopyran-3-yl Gallate; (-)-EPIGALLOCATECHIN GALLATE (85% (-)-EPIGALLOCATECHIN GALLATE, 10% (-)-EPIGALLOCATECHIN, 5% (-)-EPICATECHIN GALLATE); (-)-EPIGALLOCATECHIN-3-O-GALLATE (EGCG) (CONSTITUENT OF POWDERED DECAFFEINATED GREEN TEA EXTRACT); (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl-3,4,5-trihydroxybenzoate; (2R-cis)-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl 3,4,5-Trihydroxybenzoate; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl]3,4,5-trihydroxybenzoate; 2041570-28-7; 3,4-Dihydro-5,7-dihydroxy-2R-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3R-yl-3,4,5-trihydroxybenzoate
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 458.4
Lipid-water partition coefficient (xlogp) 1.2
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 8
Hydrogen Bond Acceptor Count (hbondacc) 11
Chemical Identifiers
Formula
C22H18O11
IUPAC Name
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Canonical SMILES
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
InChI
InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
InChIKey
WMBWREPUVVBILR-WIYYLYMNSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
DA-P3
 Probe Info  		15 uM Human normal cells (HEK-293T) [1]

Target(s) List of this Competitor

118 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(E3-independent) E2 ubiquitin-conjugating enzyme (UBE2O) LDTP11601 14.88  LDD0183 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) LDTP02984 46.21  LDD0183 
3'-5' RNA helicase YTHDC2 (YTHDC2) LDTP11996 11.69  LDD0183 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 27.21  LDD0183 
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1) LDTP05761 12.37  LDD0183 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 11.46  LDD0183 
Activating signal cointegrator 1 complex subunit 3 (ASCC3) LDTP08826 9.97  LDD0183 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 10.18  LDD0183 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 16.19  LDD0183 
Alpha-enolase (ENO1) LDTP02159 5.40  LDD0183 
Amidophosphoribosyltransferase (PPAT) LDTP05480 9.83  LDD0183 
AMP deaminase 2 (AMPD2) LDTP05289 9.99  LDD0183 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 5.73  LDD0183 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 4.93  LDD0183 
ATP-citrate synthase (ACLY) LDTP04561 7.46  LDD0183 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 4.86  LDD0183 
Casein kinase II subunit alpha' (CSNK2A2) LDTP03011 6.89  LDD0183 
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (PDE3B) LDTP05845 11.15  LDD0183 
CTP synthase 1 (CTPS1) LDTP02922 21.69  LDD0183 
Cyclin-dependent kinase 5 (CDK5) LDTP05245 4.25  LDD0183 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 5.44  LDD0183 
E3 ubiquitin-protein ligase HECTD1 (HECTD1) LDTP13574 41.09  LDD0183 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 14.56  LDD0183 
E3 ubiquitin-protein ligase Midline-1 (MID1) LDTP00611 7.49  LDD0183 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 13.85  LDD0183 
Elongation factor 2 (EEF2) LDTP02672 4.98  LDD0183 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 4.58  LDD0183 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 84.41  LDD0183 
Fatty acid synthase (FASN) LDTP04243 10.12  LDD0183 
Galactokinase (GALK1) LDTP04424 9.14  LDD0183 
Glutamate--cysteine ligase regulatory subunit (GCLM) LDTP04186 8.96  LDD0183 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 9.50  LDD0183 
Glutaredoxin-3 (GLRX3) LDTP01374 4.48  LDD0183 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 4.16  LDD0183 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 16.78  LDD0183 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 39.75  LDD0183 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 11.64  LDD0183 
HBS1-like protein (HBS1L) LDTP14019 4.01  LDD0183 
Heme oxygenase 2 (HMOX2) LDTP03540 5.42  LDD0183 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 20.04  LDD0183 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 9.02  LDD0183 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 5.72  LDD0183 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 12.81  LDD0183 
Inorganic pyrophosphatase (PPA1) LDTP14854 6.40  LDD0183 
Inosine triphosphate pyrophosphatase (ITPA) LDTP11432 5.16  LDD0183 
Inositol hexakisphosphate kinase 1 (IP6K1) LDTP09792 5.63  LDD0183 
Inositol-3-phosphate synthase 1 (ISYNA1) LDTP12364 11.63  LDD0183 
Insulin-degrading enzyme (IDE) LDTP02743 9.56  LDD0183 
Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2) LDTP03003 9.72  LDD0183 
Interleukin-1 receptor-associated kinase 1 (IRAK1) LDTP04435 25.35  LDD0183 
Kinesin-like protein KIF11 (KIF11) LDTP04519 9.88  LDD0183 
Kinesin-like protein KIF1A (KIF1A) LDTP05639 29.94  LDD0183 
Kinesin-like protein KIF2C (KIF2C) LDTP10935 23.90  LDD0183 
Kinesin-like protein KIF7 (KIF7) LDTP06695 7.58  LDD0183 
Lactoylglutathione lyase (GLO1) LDTP05434 7.33  LDD0183 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 17.29  LDD0183 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 7.73  LDD0183 
mRNA-decapping enzyme 1A (DCP1A) LDTP12371 4.69  LDD0183 
Myotubularin-related protein 1 (MTMR1) LDTP05943 4.35  LDD0183 
N-acylneuraminate cytidylyltransferase (CMAS) LDTP09228 4.43  LDD0183 
N-alpha-acetyltransferase 10 (NAA10) LDTP03938 15.10  LDD0183 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 5.51  LDD0183 
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (PAN2) LDTP06874 4.21  LDD0183 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 4.01  LDD0183 
Peptidyl-prolyl cis-trans isomerase FKBP3 (FKBP3) LDTP05255 4.65  LDD0183 
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) LDTP06104 6.09  LDD0183 
Phosphatase and actin regulator 4 (PHACTR4) LDTP08684 14.03  LDD0183 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 4.67  LDD0183 
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPSAP2) LDTP00927 12.47  LDD0183 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 7.54  LDD0183 
Phosphoserine aminotransferase (PSAT1) LDTP14198 5.78  LDD0183 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 5.99  LDD0183 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 4.02  LDD0183 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 6.14  LDD0183 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 5.09  LDD0183 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 8.04  LDD0183 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 8.89  LDD0183 
Protein disulfide-isomerase A5 (PDIA5) LDTP06145 4.01  LDD0183 
Protein NDRG3 (NDRG3) LDTP18530 9.00  LDD0183 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 7.51  LDD0183 
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (RPAP2) LDTP08615 34.80  LDD0183 
RAF proto-oncogene serine/threonine-protein kinase (RAF1) LDTP02002 4.68  LDD0183 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 5.57  LDD0183 
RNA-binding protein NOB1 (NOB1) LDTP13589 7.08  LDD0183 
S-formylglutathione hydrolase (ESD) LDTP02521 5.49  LDD0183 
Sentrin-specific protease 1 (SENP1) LDTP12983 4.59  LDD0183 
Serine/threonine-protein kinase mTOR (MTOR) LDTP03980 12.13  LDD0183 
Serine/threonine-protein kinase N2 (PKN2) LDTP06536 5.00  LDD0183 
Serine/threonine-protein kinase Nek9 (NEK9) LDTP09412 131.82  LDD0183 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) LDTP06199 10.81  LDD0183 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 6.29  LDD0183 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 6.86  LDD0183 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 5.24  LDD0183 
Spermidine synthase (SRM) LDTP03008 4.08  LDD0183 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 11.97  LDD0183 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 4.15  LDD0183 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 7.25  LDD0183 
Thimet oligopeptidase (THOP1) LDTP04542 36.01  LDD0183 
Threonine--tRNA ligase 2, cytoplasmic (TARS3) LDTP00047 4.64  LDD0183 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 9.48  LDD0183 
Triosephosphate isomerase (TPI1) LDTP04851 5.45  LDD0183 
tRNA (guanine(6)-N2)-methyltransferase THUMP3 (THUMPD3) LDTP11266 9.23  LDD0183 
tRNA endonuclease ANKZF1 (ANKZF1) LDTP12072 7.76  LDD0183 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 4.59  LDD0183 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 11.57  LDD0183 
Tyrosine-protein kinase CSK (CSK) LDTP03944 4.67  LDD0183 
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) LDTP05475 14.51  LDD0183 
Ubiquitin carboxyl-terminal hydrolase 10 (USP10) LDTP06190 75.51  LDD0183 
Ubiquitin carboxyl-terminal hydrolase 19 (USP19) LDTP01474 18.67  LDD0183 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 7.66  LDD0183 
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL1) LDTP02383 4.20  LDD0183 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 6.49  LDD0183 
Ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2) LDTP06482 4.16  LDD0183 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 32.63  LDD0183 
Ubiquitin-like-conjugating enzyme ATG3 (ATG3) LDTP12599 45.90  LDD0183 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 5.85  LDD0183 
Uridine-cytidine kinase 2 (UCK2) LDTP11571 10.99  LDD0183 
Xaa-Arg dipeptidase (PM20D2) LDTP08666 8.73  LDD0183 
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⏷ Show the Full List of 118 Enzyme
27 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein theta (YWHAQ) LDTP03385 5.93  LDD0183 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 5.37  LDD0183 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 7.16  LDD0183 
Cystatin-B (CSTB) LDTP02009 14.03  LDD0183 
Endophilin-B1 (SH3GLB1) LDTP13953 33.22  LDD0183 
Exocyst complex component 7 (EXOC7) LDTP13716 5.23  LDD0183 
Exocyst complex component 8 (EXOC8) LDTP08651 4.40  LDD0183 
Exportin-5 (XPO5) LDTP12142 5.76  LDD0183 
Exportin-T (XPOT) LDTP00810 4.67  LDD0183 
Extended synaptotagmin-1 (ESYT1) LDTP11161 5.87  LDD0183 
G2/mitotic-specific cyclin-B1 (CCNB1) LDTP02735 5.89  LDD0183 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 4.39  LDD0183 
Importin-4 (IPO4) LDTP09515 10.11  LDD0183 
Importin-5 (IPO5) LDTP00266 8.89  LDD0183 
Importin-7 (IPO7) LDTP01574 6.75  LDD0183 
Methylosome subunit pICln (CLNS1A) LDTP04597 9.20  LDD0183 
Nuclear pore complex protein Nup50 (NUP50) LDTP13498 5.06  LDD0183 
Nuclear pore glycoprotein p62 (NUP62) LDTP03839 5.19  LDD0183 
PDZ domain-containing protein 8 (PDZD8) LDTP09165 5.51  LDD0183 
Pericentriolar material 1 protein (PCM1) LDTP06331 14.29  LDD0183 
Phosphatidylinositol transfer protein alpha isoform (PITPNA) LDTP05236 4.53  LDD0183 
Reticulon-1 (RTN1) LDTP06633 10.17  LDD0183 
Signal recognition particle 19 kDa protein (SRP19) LDTP02330 96.52  LDD0183 
Sorting nexin-6 (SNX6) LDTP13661 6.72  LDD0183 
Syntaxin-17 (STX17) LDTP04770 9.73  LDD0183 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 4.18  LDD0183 
Wolframin (WFS1) LDTP01380 4.44  LDD0183 
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⏷ Show the Full List of 27 Transporter and channel
7 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 4.24  LDD0183 
DnaJ homolog subfamily C member 2 (DNAJC2) LDTP10891 9.31  LDD0183 
Ribosome quality control complex subunit TCF25 (TCF25) LDTP11060 11.48  LDD0183 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 104.51  LDD0183 
Transcription factor BTF3 (BTF3) LDTP03043 6.28  LDD0183 
Transcriptional activator protein Pur-alpha (PURA) LDTP05248 19.54  LDD0183 
Zinc finger protein 629 (ZNF629) LDTP13198 4.82  LDD0183 
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⏷ Show the Full List of 7 Transcription factor
126 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
A-kinase anchor protein 1, mitochondrial (AKAP1) LDTP09837 4.08  LDD0183 
A-kinase anchor protein 11 (AKAP11) LDTP13439 29.36  LDD0183 
ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) LDTP08950 20.17  LDD0183 
AH receptor-interacting protein (AIP) LDTP00202 9.83  LDD0183 
Anamorsin (CIAPIN1) LDTP07385 10.36  LDD0183 
Anillin (ANLN) LDTP12443 40.00  LDD0183 
Ankyrin repeat and KH domain-containing protein 1 (ANKHD1) LDTP08573 46.59  LDD0183 
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (ACAP1) LDTP06285 4.86  LDD0183 
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) LDTP10656 29.50  LDD0183 
Ataxin-10 (ATXN10) LDTP13091 5.42  LDD0183 
Ataxin-2 (ATXN2) LDTP10947 4.68  LDD0183 
Ataxin-2-like protein (ATXN2L) LDTP09655 8.70  LDD0183 
BAG family molecular chaperone regulator 2 (BAG2) LDTP01683 14.70  LDD0183 
BAG family molecular chaperone regulator 3 (BAG3) LDTP01684 46.43  LDD0183 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 5.54  LDD0183 
BLOC-1-related complex subunit 6 (BORCS6) LDTP10361 5.46  LDD0183 
BolA-like protein 2 (BOLA2; BOLA2B) LDTP11870 23.53  LDD0183 
BTB/POZ domain-containing protein KCTD12 (KCTD12) LDTP15705 35.28  LDD0183 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 17.01  LDD0183 
Calmodulin-regulated spectrin-associated protein 3 (CAMSAP3) LDTP13005 7.01  LDD0183 
Calpastatin (CAST) LDTP03079 31.43  LDD0183 
Calponin-3 (CNN3) LDTP06383 10.30  LDD0183 
Centriolar coiled-coil protein of 110 kDa (CCP110) LDTP00737 22.30  LDD0183 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 4.30  LDD0183 
CLIP-associating protein 2 (CLASP2) LDTP01129 6.59  LDD0183 
Clustered mitochondria protein homolog (CLUH) LDTP14486 10.89  LDD0183 
Coatomer subunit beta (COPB1) LDTP04570 7.76  LDD0183 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 90.26  LDD0183 
Condensin complex subunit 2 (NCAPH) LDTP06268 77.26  LDD0183 
Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A) LDTP12883 5.76  LDD0183 
COP9 signalosome complex subunit 2 (COPS2) LDTP04906 5.21  LDD0183 
Crk-like protein (CRKL) LDTP04092 25.60  LDD0183 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 10.18  LDD0183 
Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1) LDTP04560 12.13  LDD0183 
Density-regulated protein (DENR) LDTP00808 4.37  LDD0183 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 37.17  LDD0183 
Elongation factor 1-gamma (EEF1G) LDTP03367 6.09  LDD0183 
Elongator complex protein 1 (ELP1) LDTP01511 13.25  LDD0183 
Endophilin-A2 (SH3GL1) LDTP11019 8.26  LDD0183 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 11.13  LDD0183 
FLYWCH family member 2 (FLYWCH2) LDTP19852 4.63  LDD0183 
G2 and S phase-expressed protein 1 (GTSE1) LDTP12865 12.71  LDD0183 
Gamma-taxilin (TXLNG) LDTP12640 15.86  LDD0183 
Gem-associated protein 5 (GEMIN5) LDTP09504 13.93  LDD0183 
General vesicular transport factor p115 (USO1) LDTP01048 6.77  LDD0183 
GH3 domain-containing protein (GHDC) LDTP08795 10.18  LDD0183 
Glycogen debranching enzyme (AGL) LDTP03762 9.66  LDD0183 
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (GBF1) LDTP09783 6.08  LDD0183 
Golgin subfamily A member 3 (GOLGA3) LDTP05556 9.85  LDD0183 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 6.65  LDD0183 
Hsp70-binding protein 1 (HSPBP1) LDTP12914 12.11  LDD0183 
Jupiter microtubule associated homolog 2 (JPT2) LDTP12077 6.16  LDD0183 
La-related protein 1 (LARP1) LDTP07605 7.52  LDD0183 
La-related protein 4 (LARP4) LDTP07903 4.48  LDD0183 
La-related protein 4B (LARP4B) LDTP09820 7.95  LDD0183 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 4.04  LDD0183 
Leucine zipper protein 1 (LUZP1) LDTP08273 4.48  LDD0183 
Leucine-rich repeat-containing protein 40 (LRRC40) LDTP19976 15.10  LDD0183 
LIM domain-containing protein 1 (LIMD1) LDTP13241 25.59  LDD0183 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 5.77  LDD0183 
MAP7 domain-containing protein 1 (MAP7D1) LDTP14910 14.51  LDD0183 
MAP7 domain-containing protein 3 (MAP7D3) LDTP08535 19.37  LDD0183 
Melanoma-associated antigen D2 (MAGED2) LDTP13657 34.48  LDD0183 
Microtubule-associated protein 4 (MAP4) LDTP03404 17.79  LDD0183 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 21.71  LDD0183 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 4.31  LDD0183 
Nuclear migration protein nudC (NUDC) LDTP13817 8.15  LDD0183 
Nuclear transport factor 2 (NUTF2) LDTP04951 5.86  LDD0183 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 7.68  LDD0183 
Oxysterol-binding protein-related protein 9 (OSBPL9) LDTP10825 6.28  LDD0183 
PALM2-AKAP2 fusion protein (PALM2AKAP2) LDTP16261 5.57  LDD0183 
PDZ and LIM domain protein 5 (PDLIM5) LDTP10383 5.78  LDD0183 
Pericentrin (PCNT) LDTP01637 11.98  LDD0183 
Plastin-3 (PLS3) LDTP02692 5.05  LDD0183 
Pleckstrin homology domain-containing family A member 3 (PLEKHA3) LDTP12156 9.16  LDD0183 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 4.96  LDD0183 
Prefoldin subunit 2 (PFDN2) LDTP13309 4.71  LDD0183 
Prefoldin subunit 3 (VBP1) LDTP04935 39.26  LDD0183 
Profilin-1 (PFN1) LDTP02218 5.96  LDD0183 
Profilin-2 (PFN2) LDTP03706 5.70  LDD0183 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 9.30  LDD0183 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 5.72  LDD0183 
Protein diaphanous homolog 1 (DIAPH1) LDTP01011 13.59  LDD0183 
Protein diaphanous homolog 2 (DIAPH2) LDTP01069 4.24  LDD0183 
Protein diaphanous homolog 3 (DIAPH3) LDTP12596 7.60  LDD0183 
Protein HEXIM1 (HEXIM1) LDTP01484 4.40  LDD0183 
Protein LTV1 homolog (LTV1) LDTP15727 68.25  LDD0183 
Protein NEDD1 (NEDD1) LDTP09266 9.50  LDD0183 
Protein odr-4 homolog (ODR4) LDTP17214 6.36  LDD0183 
Protein PRRC2A (PRRC2A) LDTP04199 5.70  LDD0183 
Protein PRRC2B (PRRC2B) LDTP14978 17.47  LDD0183 
Protein PRRC2C (PRRC2C) LDTP14085 5.69  LDD0183 
Protein SGT1 homolog (SUGT1) LDTP13935 15.19  LDD0183 
Protein transport protein Sec24C (SEC24C) LDTP04594 9.67  LDD0183 
Pumilio homolog 1 (PUM1) LDTP06174 5.77  LDD0183 
Rab11 family-interacting protein 1 (RAB11FIP1) LDTP07742 10.31  LDD0183 
Rab3 GTPase-activating protein catalytic subunit (RAB3GAP1) LDTP06292 4.06  LDD0183 
Ran-binding protein 9 (RANBP9) LDTP10802 19.66  LDD0183 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 4.96  LDD0183 
Reticulon-3 (RTN3) LDTP01522 16.41  LDD0183 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 11.08  LDD0183 
Rho GTPase-activating protein 21 (ARHGAP21) LDTP07124 10.56  LDD0183 
Serine-threonine kinase receptor-associated protein (STRAP) LDTP13991 4.80  LDD0183 
SH3 and PX domain-containing protein 2B (SH3PXD2B) LDTP00039 22.88  LDD0183 
Shootin-1 (SHTN1) LDTP00019 39.87  LDD0183 
SLAIN motif-containing protein 1 (SLAIN1) LDTP09118 8.54  LDD0183 
Spartin (SPART) LDTP08735 12.66  LDD0183 
Src substrate cortactin (CTTN) LDTP06094 4.27  LDD0183 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 19.36  LDD0183 
Striatin-4 (STRN4) LDTP12519 5.84  LDD0183 
Survival motor neuron protein (SMN1; SMN2) LDTP06587 4.70  LDD0183 
Synapse-associated protein 1 (SYAP1) LDTP10062 9.30  LDD0183 
T-complex protein 1 subunit theta (CCT8) LDTP04390 4.14  LDD0183 
TATA element modulatory factor (TMF1) LDTP05172 16.65  LDD0183 
TBC1 domain family member 15 (TBC1D15) LDTP09363 20.46  LDD0183 
Tether containing UBX domain for GLUT4 (ASPSCR1) LDTP11530 21.27  LDD0183 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 7.71  LDD0183 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 8.64  LDD0183 
TRAF-type zinc finger domain-containing protein 1 (TRAFD1) LDTP14426 5.13  LDD0183 
Transforming acidic coiled-coil-containing protein 1 (TACC1) LDTP01210 8.55  LDD0183 
Transforming acidic coiled-coil-containing protein 3 (TACC3) LDTP14228 200.12  LDD0183 
Transgelin-2 (TAGLN2) LDTP03846 4.30  LDD0183 
Translation initiation factor eIF2B subunit delta (EIF2B4) LDTP13318 6.17  LDD0183 
Ubiquitin-fold modifier-conjugating enzyme 1 (UFC1) LDTP13978 5.06  LDD0183 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 10.51  LDD0183 
Vigilin (HDLBP) LDTP05239 7.82  LDD0183 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 15 uM
Quantitative Method LFQ
Competitor Name Epigallocatechin gallate
Competitor Concentration 150 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Interaction Atlas ID  LDD0183  Download The Altas

References

1 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348