Details of the Target

General Information of Target

Target ID LDTP00611
Target Name E3 ubiquitin-protein ligase Midline-1 (MID1)
Gene Name MID1
Gene ID 4281
Synonyms
FXY; RNF59; TRIM18; XPRF; E3 ubiquitin-protein ligase Midline-1; EC 2.3.2.27; Midin; Putative transcription factor XPRF; RING finger protein 59; RING finger protein Midline-1; RING-type E3 ubiquitin transferase Midline-1; Tripartite motif-containing protein 18
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR
HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ
FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED
EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL
LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA
NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD
TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI
FTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLK
TNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR
HYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPH
LRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHL
DCTEQLP
Target Bioclass
Enzyme
Family
TRIM/RBCC family
Subcellular location
Cytoplasm
Function
Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
Uniprot ID
O15344
Ensemble ID
ENST00000317552.9
HGNC ID
HGNC:7095

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CCK81 SNV: p.Y396H DBIA    Probe Info 
COLO679 SNV: p.P655L DBIA    Probe Info 
HEC1 SNV: p.R160C DBIA    Probe Info 
KYSE30 SNV: p.E163D DBIA    Probe Info 
MDAMB453 SNV: p.Q208K DBIA    Probe Info 
NCIH2286 SNV: p.D489Y .
OVK18 SNV: p.T58A DBIA    Probe Info 
U2OS SNV: p.L355F .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 13 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K333(5.88); K74(10.00)  LDD0277  [1]
P11
 Probe Info  		12.45  LDD0201  [2]
BTD
 Probe Info  		C302(0.88)  LDD2093  [3]
DA-P3
 Probe Info  		7.49  LDD0183  [4]
Acrolein
 Probe Info  		N.A.  LDD0222  [5]
DBIA
 Probe Info  		C119(1.04); C122(1.04); C578(0.92)  LDD0078  [6]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [7]
WYneN
 Probe Info  		N.A.  LDD0021  [8]
IPM
 Probe Info  		N.A.  LDD0005  [8]
TFBX
 Probe Info  		C248(0.00); C302(0.00)  LDD0148  [9]
VSF
 Probe Info  		N.A.  LDD0007  [8]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [10]
AOyne
 Probe Info  		14.50  LDD0443  [11]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C302(1.06)  LDD2117  [3]
 LDCM0214  AC1 HCT 116 C119(1.14); C122(1.14); C134(0.59); C145(0.59)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C119(1.21); C122(1.21); C134(1.15); C137(1.02)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C119(0.88); C122(0.88); C142(0.85); C145(0.85)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C119(0.99); C122(0.99); C142(0.92); C145(0.92)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C119(0.99); C122(0.99); C142(0.87); C145(0.87)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C119(1.04); C122(1.04); C142(1.05); C145(1.05)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C119(1.08); C122(1.08); C142(1.01); C145(1.01)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C119(1.15); C122(1.15); C142(0.99); C145(0.99)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C119(1.17); C122(1.17); C142(0.97); C145(0.97)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C119(1.05); C122(1.05); C142(1.01); C145(0.76)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C119(1.07); C122(1.07); C142(0.70); C145(1.09)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C119(0.86); C122(0.86); C142(0.73); C145(1.07)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C119(1.21); C122(1.21); C134(1.55); C137(1.35)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C119(0.94); C122(0.94); C142(0.79); C145(0.73)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C119(0.97); C122(0.97); C142(0.82); C145(0.86)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C119(1.08); C122(1.08); C142(0.98); C145(0.77)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C119(1.04); C122(1.04); C134(0.93); C137(0.93)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C119(0.96); C122(0.83); C134(1.37); C137(1.31)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C119(0.64); C122(0.81); C134(1.19); C137(1.42)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C119(1.08); C122(0.87); C134(1.12); C137(1.26)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C119(1.17); C122(0.99); C134(1.10); C137(1.06)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C119(1.03); C122(0.91); C134(0.94); C137(0.99)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C119(1.25); C122(0.82); C134(1.05); C137(1.10)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C119(1.18); C122(1.18); C134(0.72); C137(0.76)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C119(1.10); C122(1.15); C134(0.78); C137(0.93)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C119(1.53); C122(1.00); C134(1.39); C137(1.60)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C119(1.35); C122(0.92); C134(1.18); C137(1.03)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C119(0.96); C122(0.89); C134(1.29); C137(1.24)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C119(1.29); C122(0.83); C134(0.91); C137(1.02)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C119(1.66); C122(1.04); C134(1.10); C137(1.16)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C119(1.24); C122(1.09); C134(1.09); C137(1.06)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C119(1.40); C122(1.04); C134(1.33); C137(1.44)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C119(0.55); C122(0.55); C137(1.29); C142(0.57)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C119(0.48); C122(0.48); C137(0.98); C142(0.61)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C119(0.58); C122(0.58); C137(1.20); C142(0.59)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C119(0.54); C122(0.54); C137(1.16); C142(0.64)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C119(0.63); C122(0.63); C137(1.02); C142(0.73)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C119(0.59); C122(0.59); C137(1.12); C142(0.55)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C119(0.52); C122(0.52); C137(1.43); C142(0.57)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C119(0.65); C122(0.65); C137(1.38); C142(0.69)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C119(0.60); C122(0.60); C137(1.04); C142(0.72)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C119(0.60); C122(0.60); C137(0.93); C142(0.69)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C119(0.51); C122(0.51); C137(1.18); C142(0.73)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C119(0.63); C122(0.63); C137(1.07); C142(0.98)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C119(1.25); C122(1.25); C134(1.06); C137(1.12)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C119(0.62); C122(0.62); C137(1.20); C142(0.75)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C119(0.67); C122(0.67); C137(1.08); C142(0.80)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C119(0.66); C122(0.66); C137(1.02); C142(0.68)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C248(0.86); C142(0.90); C119(0.94); C122(0.94)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C248(0.91); C580(0.99); C122(1.12); C119(1.13)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C119(0.99); C122(1.02); C248(1.09); C142(1.11)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C248(1.06); C122(1.07); C119(1.10); C145(1.19)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C580(1.00); C248(1.04); C142(1.14); C137(1.24)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C142(1.14); C248(1.18); C137(1.24); C145(1.27)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C248(0.98); C119(1.19); C145(1.25); C137(1.28)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C248(0.80); C578(1.01); C647(1.08); C662(1.08)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C580(0.95); C248(0.98); C119(1.00); C122(1.02)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C248(0.99); C647(1.06); C662(1.06); C580(1.08)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C248(0.98); C119(1.18); C122(1.19); C137(1.19)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C248(1.01); C580(1.31); C137(1.38); C119(1.40)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C119(1.15); C122(1.12); C137(1.17); C142(1.28)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C119(1.14); C122(1.12); C137(1.26); C142(1.48)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C119(1.00); C122(0.95); C137(1.10); C142(1.29)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C119(0.95); C122(0.92); C137(0.99); C142(1.63)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C119(0.61); C122(0.61); C580(1.01); C42(1.02)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C119(0.59); C122(0.59); C42(0.73); C578(0.89)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C119(0.57); C122(0.57); C42(0.76); C580(1.21)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C134(0.64); C145(0.64); C578(0.98); C248(1.06)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C119(0.54); C122(0.54); C42(0.95); C580(1.18)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C119(0.57); C122(0.57); C42(0.84); C580(1.05)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C119(0.56); C122(0.56); C42(0.88); C578(1.03)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C119(0.59); C122(0.59); C42(0.76); C578(1.15)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C119(0.49); C122(0.49); C42(1.01); C580(1.05)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C42(0.71); C375(0.75); C119(0.96); C122(0.96)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C42(0.71); C302(0.83); C375(0.86); C119(1.15)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C42(0.76); C302(0.81); C375(0.86); C142(1.19)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C302(0.81); C42(0.91); C375(0.94); C119(1.04)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C302(0.67); C375(0.85); C42(0.96); C119(1.06)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C134(0.62); C145(0.62); C578(0.83); C42(0.90)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C302(0.63); C375(0.93); C119(1.02); C122(1.02)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C302(0.79); C42(0.86); C375(1.02); C142(1.05)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C302(0.62); C375(0.79); C42(0.88); C119(1.08)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C42(1.03); C375(1.05); C302(1.05); C248(1.16)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C375(0.78); C119(0.90); C122(0.90); C42(0.91)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C647(0.64); C662(0.64); C137(0.85); C578(0.86)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C647(0.70); C662(0.70); C119(0.90); C122(0.90)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C647(0.70); C662(0.70); C137(0.72); C145(0.93)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C647(0.90); C662(0.90); C302(0.99); C119(1.01)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C578(0.78); C302(0.81); C137(0.90); C119(1.02)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C134(0.66); C145(0.66); C42(0.83); C578(0.86)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C137(0.71); C302(0.92); C119(0.95); C122(0.95)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C647(0.71); C662(0.71); C142(0.91); C302(0.95)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C302(0.80); C647(0.92); C662(0.92); C137(0.93)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C647(0.87); C662(0.87); C302(0.91); C248(1.00)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C119(0.85); C122(0.85); C137(0.92); C248(0.96)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C137(0.80); C119(0.83); C122(0.83); C145(0.90)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C580(1.11); C302(1.16); C119(1.16); C122(1.16)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C580(1.06); C302(1.09); C119(1.15); C122(1.15)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C302(1.08); C248(1.12); C580(1.30); C578(1.34)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C302(0.77); C248(1.02); C119(1.08); C122(1.08)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C134(0.69); C145(0.69); C42(0.75); C578(0.88)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C248(1.00); C119(1.03); C122(1.03); C302(1.06)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C375(1.15); C119(1.18); C122(1.18); C248(1.19)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C248(1.13); C580(1.13); C119(1.28); C122(1.28)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C302(0.84); C248(1.10); C580(1.11); C375(1.19)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C580(1.04); C578(1.11); C375(1.14); C302(1.15)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C302(0.89); C580(1.10); C248(1.11); C375(1.26)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C302(0.88); C580(1.17); C248(1.20); C119(1.40)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C302(0.69); C580(0.83); C119(0.93); C122(0.93)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C302(0.68); C119(0.90); C122(0.90); C137(0.94)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C302(0.66); C580(0.83); C119(0.90); C122(0.90)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C248(0.81); C137(0.81); C647(0.91); C662(0.91)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C302(0.66); C580(0.81); C248(1.09); C119(1.11)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C302(0.67); C580(0.89); C248(1.13); C578(1.15)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C302(0.60); C248(0.87); C580(0.89); C119(1.12)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C302(0.60); C580(0.81); C119(1.00); C122(1.00)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C302(0.64); C580(0.74); C248(1.00); C119(1.12)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C302(0.56); C134(0.87); C145(0.96); C248(0.98)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C302(0.58); C580(0.91); C134(0.93); C145(0.94)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C302(0.38); C580(0.71); C248(0.83); C578(0.92)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C647(0.65); C662(0.65); C248(0.71); C578(0.82)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C647(0.78); C662(0.78); C248(0.81); C302(1.00)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C137(0.76); C248(0.78); C134(0.79); C145(0.90)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C42(0.60); C56(0.60); C578(0.80); C248(0.84)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C647(0.81); C662(0.81); C248(0.91); C42(0.92)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C578(0.81); C647(0.84); C662(0.84); C248(0.86)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C42(0.84); C56(0.84); C302(0.88); C248(0.89)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C248(0.86); C42(0.91); C56(0.91); C578(0.95)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C248(0.88); C578(0.97); C42(1.00); C56(1.00)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C248(0.80); C42(0.92); C56(0.92); C302(1.03)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C647(0.83); C662(0.83); C248(0.84); C42(0.84)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C647(0.65); C662(0.65); C42(0.75); C56(0.75)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C647(0.72); C662(0.72); C42(0.83); C56(0.83)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C578(0.82); C248(0.83); C580(1.01); C134(1.07)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C248(0.78); C647(0.85); C662(0.85); C302(0.92)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C647(0.65); C662(0.65); C578(0.72); C42(0.74)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C578(0.70); C42(0.74); C56(0.74); C302(0.92)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C248(0.93); C302(0.95); C578(1.04); C142(1.10)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C248(0.83); C578(0.97); C302(0.99); C142(1.02)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C302(0.96); C248(0.98); C580(0.98); C119(1.00)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C302(0.95); C248(0.99); C119(1.03); C122(1.03)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C302(0.88); C248(0.89); C142(0.94); C580(0.97)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C302(0.86); C248(0.88); C580(0.97); C578(0.99)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C248(0.86); C302(0.98); C142(1.06); C578(1.09)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C302(0.87); C248(0.96); C119(1.12); C122(1.12)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C248(0.85); C142(0.96); C302(1.09); C578(1.15)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C248(0.83); C142(0.88); C302(1.01); C578(1.18)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C580(0.85); C248(0.91); C302(0.99); C578(1.08)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C142(0.80); C248(0.87); C580(0.88); C578(1.08)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C119(0.92); C122(0.92); C302(0.93); C248(0.96)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C248(0.69); C142(0.86); C119(1.13); C122(1.13)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C248(0.84); C302(0.88); C580(1.07); C578(1.11)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C578(0.59); C302(0.82); C119(0.98); C122(0.98)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C647(0.76); C662(0.76); C142(0.77); C145(0.77)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C119(1.10); C122(1.10); C134(0.90); C137(0.86)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C248(0.81); C647(0.84); C662(0.84); C578(0.85)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C248(0.96); C578(0.96); C134(1.03); C137(1.09)  LDD0592  [6]
 LDCM0020  ARS-1620 HCC44 C119(1.04); C122(1.04); C578(0.92)  LDD0078  [6]
 LDCM0088  C45 HEK-293T 12.45  LDD0201  [2]
 LDCM0087  Capsaicin HEK-293T 5.19  LDD0185  [4]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [5]
 LDCM0367  CL1 HCT 116 C647(0.69); C662(0.69); C578(0.77); C119(0.79)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C375(0.77); C578(0.86); C580(0.91); C248(0.94)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C134(0.73); C145(0.73); C578(0.83); C248(0.90)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C248(0.81); C578(1.03); C134(1.20); C137(1.25)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C578(0.79); C248(0.81); C134(0.92); C137(1.05)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C248(0.68); C578(0.81); C137(0.91); C134(0.93)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C137(0.82); C248(0.88); C134(0.91); C647(0.93)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C119(0.55); C122(0.55); C42(0.89); C578(1.05)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C119(0.57); C122(0.57); C42(0.78); C578(0.99)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C119(0.63); C122(0.63); C42(0.90); C578(1.04)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C119(0.52); C122(0.52); C578(0.95); C42(0.99)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C119(0.68); C122(0.68); C42(0.92); C578(1.09)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C42(0.89); C56(0.89); C248(1.01); C580(1.03)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C119(0.66); C122(0.66); C42(0.84); C578(1.03)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C119(0.67); C122(0.67); C42(0.92); C578(1.02)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C42(0.85); C248(0.91); C119(0.96); C122(0.96)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C302(0.69); C119(0.94); C122(0.94); C142(0.99)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C302(0.74); C375(0.79); C119(0.88); C122(0.88)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C302(0.87); C375(1.01); C42(1.09); C119(1.13)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C375(0.88); C248(0.93); C42(0.98); C302(1.06)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C578(0.88); C302(0.91); C137(0.97); C248(1.15)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C119(0.83); C122(0.83); C302(0.96); C647(0.99)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C137(0.72); C302(0.92); C145(0.94); C119(0.96)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C375(1.01); C248(1.09); C42(1.09); C56(1.09)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C647(0.90); C662(0.90); C302(0.90); C119(0.99)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C375(0.88); C578(0.93); C248(1.09); C580(1.18)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C302(0.99); C375(1.10); C580(1.24); C248(1.27)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C302(0.76); C375(1.01); C580(1.13); C578(1.24)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C302(1.12); C580(1.20); C375(1.30); C119(1.33)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C134(0.86); C302(0.87); C145(0.96); C578(1.00)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C302(0.69); C580(0.90); C119(0.91); C122(0.91)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C302(0.75); C580(0.83); C248(0.98); C119(1.05)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C302(0.67); C580(0.77); C119(0.96); C122(0.96)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C578(0.85); C375(0.95); C248(1.01); C580(1.15)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C375(0.87); C248(0.91); C119(0.96); C122(0.96)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C375(0.88); C248(0.89); C578(0.93); C580(1.02)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C578(0.83); C42(0.91); C56(0.91); C302(0.94)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C580(0.77); C119(0.92); C122(0.92); C248(1.05)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C248(0.94); C142(0.97); C145(0.97); C302(0.98)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C580(0.87); C142(0.90); C145(0.90); C248(1.02)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C578(0.66); C647(0.73); C662(0.73); C375(0.86)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C248(1.04); C580(1.06); C302(1.27); C42(1.33)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C580(1.05); C142(1.12); C145(1.12); C248(1.15)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C142(0.97); C145(0.97); C302(1.08); C578(1.09)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C42(0.79); C56(0.79); C580(0.92); C142(0.98)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C578(0.97); C42(0.98); C56(0.98); C580(0.98)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C119(2.00); C122(2.00); C142(1.07); C145(1.07)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C119(1.55); C122(1.55); C142(0.99); C145(0.99)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C119(1.73); C122(1.73); C142(0.84); C145(0.84)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C119(1.67); C122(1.67); C142(1.00); C145(1.00)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C119(1.72); C122(1.72); C142(1.07); C145(1.07)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C119(1.01); C122(1.01); C134(1.39); C137(1.39)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C119(1.58); C122(1.58); C142(0.96); C145(0.96)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C119(0.91); C122(0.91); C142(0.76); C145(0.76)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C119(1.07); C122(1.07); C248(1.03); C302(0.96)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C119(0.85); C122(0.85); C248(0.88); C302(0.78)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C119(1.11); C122(1.11); C248(1.05); C302(0.78)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C119(1.16); C122(1.16); C248(1.07); C302(0.88)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C119(1.12); C122(1.12); C248(1.00); C302(0.95)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C119(1.10); C122(1.10); C248(1.02); C302(0.69)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C119(1.17); C122(1.17); C248(1.03); C302(0.80)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C119(1.10); C122(1.10); C134(0.89); C137(0.89)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C119(1.00); C122(1.00); C248(0.88); C302(0.72)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C119(1.18); C122(1.18); C248(0.96); C302(0.93)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C119(1.16); C122(1.16); C248(0.89); C302(0.70)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C119(1.24); C122(1.24); C248(1.07); C302(0.92)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C119(0.99); C122(0.99); C248(1.08); C302(0.86)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C119(1.04); C122(1.04); C248(1.02); C302(0.73)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C119(0.94); C122(0.94); C248(0.95); C578(0.83)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C119(0.87); C122(0.87); C248(1.08); C578(1.00)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C119(0.95); C122(0.95); C248(0.84); C578(0.95)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C119(0.89); C122(0.89); C248(0.96); C578(0.92)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C119(1.07); C122(1.07); C134(0.82); C137(0.82)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C119(0.87); C122(0.87); C248(0.98); C578(0.91)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C119(1.03); C122(1.03); C248(0.78); C578(0.88)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C119(1.05); C122(1.05); C248(0.93); C578(0.95)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C119(1.00); C122(1.00); C248(0.85); C578(1.21)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C119(1.04); C122(1.04); C248(0.86); C578(1.00)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C119(1.02); C122(1.02); C248(0.87); C578(0.95)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C119(1.24); C122(1.24); C248(0.84); C578(1.09)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C119(0.96); C122(0.96); C248(0.74); C578(1.25)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C119(1.04); C122(1.04); C248(0.97); C578(1.23)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C119(0.98); C122(0.98); C248(1.13); C578(1.14)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C119(1.05); C122(1.05); C134(0.99); C137(0.99)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C119(0.99); C122(0.99); C248(0.91); C578(0.98)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C578(1.06); C580(0.84); C647(1.00); C662(1.00)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C578(0.97); C580(1.02); C647(1.26); C662(1.26)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C578(1.19); C580(0.87); C647(1.21); C662(1.21)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C578(0.91); C580(0.98); C647(1.17); C662(1.17)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C578(1.07); C580(0.68); C647(1.27); C662(1.27)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C578(0.93); C580(0.91); C647(1.54); C662(1.54)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C578(1.34); C580(0.62); C647(1.35); C662(1.35)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C578(1.14); C580(0.50); C647(1.38); C662(1.38)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C578(1.28); C580(0.72); C647(1.14); C662(1.14)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C119(1.14); C122(1.14); C134(1.02); C137(1.02)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C578(1.09); C580(0.36); C647(1.63); C662(1.63)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C578(1.04); C580(0.69); C647(1.27); C662(1.27)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C578(1.18); C580(0.54); C647(0.98); C662(0.98)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C578(1.41); C580(0.68); C647(1.15); C662(1.15)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C578(1.24); C580(0.59); C647(1.60); C662(1.60)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C119(0.92); C122(0.92); C248(1.04); C375(1.51)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C119(0.74); C122(0.74); C248(0.83); C375(0.96)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C119(0.88); C122(0.88); C248(0.88); C375(0.90)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C119(1.16); C122(1.16); C248(1.06); C375(1.20)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C119(1.03); C122(1.03); C134(1.29); C137(1.29)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C119(0.86); C122(0.86); C248(1.20); C375(1.01)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C119(0.94); C122(0.94); C248(1.20); C375(0.97)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C119(1.15); C122(1.15); C248(1.39); C375(1.07)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C119(0.92); C122(0.92); C248(1.22); C375(1.23)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C119(1.08); C122(1.08); C248(1.21); C375(1.16)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C119(0.95); C122(0.95); C248(1.10); C375(0.98)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C119(0.80); C122(0.80); C248(1.01); C375(1.12)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C119(0.82); C122(0.82); C248(1.13); C375(1.05)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C119(0.86); C122(0.86); C248(1.28); C375(1.12)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C119(1.03); C122(1.03); C248(1.41); C375(1.62)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C119(1.19); C122(1.19); C134(1.42); C137(1.42)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C119(0.60); C122(0.60); C248(1.09); C375(0.99)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C119(1.33); C122(1.33); C134(0.66); C145(0.66)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C119(1.13); C122(1.13); C134(0.60); C145(0.60)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C119(0.97); C122(0.97); C134(0.63); C145(0.63)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C119(1.10); C122(1.10); C134(0.88); C145(0.88)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C119(0.92); C122(0.92); C134(0.78); C145(0.78)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C119(1.17); C122(1.17); C134(0.80); C145(0.80)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C119(1.15); C122(1.15); C134(0.61); C145(0.61)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C119(1.17); C122(1.17); C134(0.60); C145(0.60)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C119(1.27); C122(1.27); C134(0.74); C145(0.74)  LDD0811  [6]
 LDCM0495  E2913 HEK-293T C248(0.91); C175(1.00); C375(0.91); C580(0.98)  LDD1698  [12]
 LDCM0031  Epigallocatechin gallate HEK-293T 7.49  LDD0183  [4]
 LDCM0468  Fragment33 HCT 116 C578(1.16); C580(0.73); C647(1.10); C662(1.10)  LDD0785  [6]
 LDCM0427  Fragment51 HCT 116 C119(1.33); C122(1.33); C248(1.07); C302(0.74)  LDD0744  [6]
 LDCM0022  KB02 HCT 116 C137(2.24); C142(2.24); C145(1.95); C302(1.43)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C137(2.03); C142(2.03); C145(1.72); C302(2.74)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C137(2.48); C142(2.48); C145(2.03); C302(1.44)  LDD0082  [6]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C302(0.88)  LDD2093  [3]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C302(1.54)  LDD2099  [3]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C302(1.32)  LDD2107  [3]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C302(0.52)  LDD2109  [3]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C302(1.09)  LDD2111  [3]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C302(0.70)  LDD2125  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C302(0.91)  LDD2127  [3]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C302(1.60)  LDD2135  [3]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C302(1.24)  LDD2136  [3]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C302(1.01)  LDD2137  [3]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C302(0.88)  LDD2140  [3]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C302(2.65)  LDD2144  [3]
 LDCM0628  OTUB2-COV-1 HEK-293T C580(0.67)  LDD2207  [13]
 LDCM0021  THZ1 HCT 116 C580(1.02); C187(1.04); C195(1.04); C142(1.01)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 19 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cryptochrome-2 (CRY2) DNA photolyase class-1 family Q49AN0
Peroxisomal bifunctional enzyme (EHHADH) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family Q08426
NEDD4-binding protein 1 (N4BP1) N4BP1 family O75113
Ubiquitin thioesterase OTUB2 (OTUB2) Peptidase C65 family Q96DC9
Serine/threonine-protein kinase N1 (PKN1) AGC Ser/Thr protein kinase family Q16512
Dual specificity tyrosine-phosphorylation-regulated kinase 4 (DYRK4) CMGC Ser/Thr protein kinase family Q9NR20
Kinesin-like protein KIF9 (KIF9) Kinesin family Q9HAQ2
E3 ubiquitin-protein ligase Midline-1 (MID1) TRIM/RBCC family O15344
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1) Ubiquitin-conjugating enzyme family P51668
Ubiquitin-conjugating enzyme E2 D2 (UBE2D2) Ubiquitin-conjugating enzyme family P62837
Ubiquitin-conjugating enzyme E2 D3 (UBE2D3) Ubiquitin-conjugating enzyme family P61077
Ubiquitin-conjugating enzyme E2 D4 (UBE2D4) Ubiquitin-conjugating enzyme family Q9Y2X8
Ubiquitin-conjugating enzyme E2 E2 (UBE2E2) Ubiquitin-conjugating enzyme family Q96LR5
Ubiquitin-conjugating enzyme E2 E3 (UBE2E3) Ubiquitin-conjugating enzyme family Q969T4
Ubiquitin-conjugating enzyme E2 K (UBE2K) Ubiquitin-conjugating enzyme family P61086
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) Ubiquitin-conjugating enzyme family P68036
Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6) Ubiquitin-conjugating enzyme family O14933
Germ cell-less protein-like 1 (GMCL1) . Q96IK5
Ubiquitin domain-containing protein 1 (UBTD1) . Q9HAC8
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hsp90 co-chaperone Cdc37 (CDC37) CDC37 family Q16543
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 618 (ZNF618) Krueppel C2H2-type zinc-finger protein family Q5T7W0
Homeobox protein MOX-1 (MEOX1) . P50221
Other
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Bystin (BYSL) Bystin family Q13895
Protein FAM50B (FAM50B) FAM50 family Q9Y247
Immunoglobulin-binding protein 1 (IGBP1) IGBP1/TAP42 family P78318
Pentatricopeptide repeat-containing protein 2, mitochondrial (PTCD2) PTCD2 family Q8WV60
Elongin-A (ELOA) . Q14241
Transcription elongation factor A N-terminal and central domain-containing protein (TCEANC) . Q8N8B7

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors. J Am Chem Soc. 2022 Mar 30;144(12):5377-5388. doi: 10.1021/jacs.1c12748. Epub 2022 Mar 2.
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
5 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
8 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
11 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
12 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
13 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.