Details of the Target

General Information of Target

Target ID LDTP04519
Target Name Kinesin-like protein KIF11 (KIF11)
Gene Name KIF11
Gene ID 3832
Synonyms
EG5; KNSL1; TRIP5; Kinesin-like protein KIF11; Kinesin-like protein 1; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADK
SSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERS
PNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSE
RLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFS
VTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT
ALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIL
NKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIV
ELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY
ITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNS
LFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHV
SQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKT
SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ
ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS
QELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNER
EQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNE
TIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLM
MLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGK
DKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL
Target Type
Clinical trial
Target Bioclass
Enzyme
Family
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily
Subcellular location
Cytoplasm
Function
Motor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface.
TTD ID
T28484
Uniprot ID
P52732
DrugMap ID
TTTRP0H
Ensemble ID
ENST00000260731.5
HGNC ID
HGNC:6388
ChEMBL ID
CHEMBL4581

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 28 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
TH211
 Probe Info  		Y211(20.00)  LDD0257  [2]
STPyne
 Probe Info  		K280(1.32); K715(10.00)  LDD0277  [3]
Probe 1
 Probe Info  		Y378(21.11)  LDD3495  [4]
BTD
 Probe Info  		C723(1.29)  LDD1700  [5]
DA-P3
 Probe Info  		4.27  LDD0181  [6]
AHL-Pu-1
 Probe Info  		C854(3.94); C740(3.73)  LDD0168  [7]
Alkyne-RA190
 Probe Info  		2.39  LDD0299  [8]
HHS-465
 Probe Info  		Y932(6.84); Y934(4.32)  LDD2237  [9]
DBIA
 Probe Info  		C723(1.08); C773(0.95)  LDD0078  [10]
ATP probe
 Probe Info  		K521(0.00); K1045(0.00)  LDD0199  [11]
4-Iodoacetamidophenylacetylene
 Probe Info  		C740(0.00); C773(0.00); C450(0.00); C704(0.00)  LDD0038  [12]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [13]
Lodoacetamide azide
 Probe Info  		C43(0.00); C740(0.00); C773(0.00); C734(0.00)  LDD0037  [12]
NAIA_4
 Probe Info  		N.A.  LDD2226  [14]
Compound 10
 Probe Info  		N.A.  LDD2216  [15]
ENE
 Probe Info  		N.A.  LDD0006  [16]
IPM
 Probe Info  		C723(0.00); C734(0.00); C911(0.00)  LDD0005  [16]
NPM
 Probe Info  		N.A.  LDD0016  [16]
SF
 Probe Info  		N.A.  LDD0028  [17]
TFBX
 Probe Info  		C740(0.00); C773(0.00)  LDD0148  [18]
VSF
 Probe Info  		C819(0.00); C740(0.00)  LDD0007  [16]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [19]
1c-yne
 Probe Info  		N.A.  LDD0228  [20]
Acrolein
 Probe Info  		C450(0.00); C911(0.00)  LDD0217  [21]
AOyne
 Probe Info  		14.70  LDD0443  [22]
NAIA_5
 Probe Info  		C43(0.00); C740(0.00); C25(0.00); C723(0.00)  LDD2223  [14]
HHS-482
 Probe Info  		Y352(0.60)  LDD2239  [9]
PAL-AfBPP Probe
Click To Hide/Show 14 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C173
 Probe Info  		5.43  LDD1853  [23]
C178
 Probe Info  		20.25  LDD1857  [23]
C367
 Probe Info  		5.82  LDD2028  [23]
C386
 Probe Info  		7.41  LDD2045  [23]
FFF probe11
 Probe Info  		20.00  LDD0471  [24]
FFF probe13
 Probe Info  		15.15  LDD0475  [24]
FFF probe14
 Probe Info  		20.00  LDD0477  [24]
FFF probe2
 Probe Info  		20.00  LDD0463  [24]
FFF probe3
 Probe Info  		17.12  LDD0464  [24]
FFF probe4
 Probe Info  		10.31  LDD0466  [24]
FFF probe6
 Probe Info  		5.30  LDD0467  [24]
STS-2
 Probe Info  		N.A.  LDD0139  [25]
VE-P
 Probe Info  		N.A.  LDD0396  [26]
OEA-DA
 Probe Info  		3.29  LDD0046  [27]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C819(0.41)  LDD2142  [5]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C723(1.01); C819(1.19)  LDD2152  [5]
 LDCM0025  4SU-RNA HEK-293T C854(3.94); C740(3.73)  LDD0168  [7]
 LDCM0026  4SU-RNA+native RNA HEK-293T C911(2.62); C740(3.72); C450(5.82)  LDD0169  [7]
 LDCM0214  AC1 HCT 116 C450(1.03); C734(1.33); C773(1.06); C854(0.85)  LDD0531  [10]
 LDCM0215  AC10 HCT 116 C450(1.27); C723(1.12); C734(1.49); C773(1.15)  LDD0532  [10]
 LDCM0216  AC100 HCT 116 C450(0.91); C723(1.03); C734(0.72); C773(0.93)  LDD0533  [10]
 LDCM0217  AC101 HCT 116 C450(1.11); C723(1.11); C734(0.86); C773(0.83)  LDD0534  [10]
 LDCM0218  AC102 HCT 116 C450(0.86); C723(1.04); C734(0.81); C773(0.90)  LDD0535  [10]
 LDCM0219  AC103 HCT 116 C450(1.10); C723(1.40); C734(0.90); C773(1.11)  LDD0536  [10]
 LDCM0220  AC104 HCT 116 C450(0.99); C723(1.25); C734(0.87); C773(1.07)  LDD0537  [10]
 LDCM0221  AC105 HCT 116 C450(1.10); C723(1.33); C734(0.86); C773(1.04)  LDD0538  [10]
 LDCM0222  AC106 HCT 116 C450(1.11); C723(1.34); C734(0.86); C773(1.08)  LDD0539  [10]
 LDCM0223  AC107 HCT 116 C450(1.18); C723(1.48); C734(1.05); C773(0.89)  LDD0540  [10]
 LDCM0224  AC108 HCT 116 C450(0.98); C723(0.78); C734(0.77); C773(1.00)  LDD0541  [10]
 LDCM0225  AC109 HCT 116 C450(0.83); C723(0.90); C734(0.67); C773(0.80)  LDD0542  [10]
 LDCM0226  AC11 HCT 116 C450(1.17); C723(1.21); C734(1.64); C773(1.27)  LDD0543  [10]
 LDCM0227  AC110 HCT 116 C450(1.03); C723(0.84); C734(0.72); C773(1.06)  LDD0544  [10]
 LDCM0228  AC111 HCT 116 C450(1.05); C723(0.95); C734(0.77); C773(1.05)  LDD0545  [10]
 LDCM0229  AC112 HCT 116 C450(0.98); C723(1.14); C734(0.91); C773(1.00)  LDD0546  [10]
 LDCM0230  AC113 HCT 116 C450(0.97); C723(0.93); C734(1.14); C773(1.14)  LDD0547  [10]
 LDCM0231  AC114 HCT 116 C450(1.21); C723(1.07); C734(0.95); C773(1.28)  LDD0548  [10]
 LDCM0232  AC115 HCT 116 C450(1.32); C723(1.13); C734(1.22); C773(1.27)  LDD0549  [10]
 LDCM0233  AC116 HCT 116 C450(1.39); C723(1.19); C734(1.14); C773(1.25)  LDD0550  [10]
 LDCM0234  AC117 HCT 116 C450(1.19); C723(1.07); C734(1.15); C773(1.14)  LDD0551  [10]
 LDCM0235  AC118 HCT 116 C450(1.23); C723(0.98); C734(1.02); C773(1.12)  LDD0552  [10]
 LDCM0236  AC119 HCT 116 C450(1.03); C723(1.10); C734(1.25); C773(1.23)  LDD0553  [10]
 LDCM0237  AC12 HCT 116 C450(1.00); C723(0.99); C734(1.48); C773(1.18)  LDD0554  [10]
 LDCM0238  AC120 HCT 116 C450(1.37); C723(1.11); C734(0.85); C773(1.20)  LDD0555  [10]
 LDCM0239  AC121 HCT 116 C450(1.14); C723(0.95); C734(0.80); C773(1.17)  LDD0556  [10]
 LDCM0240  AC122 HCT 116 C450(1.41); C723(0.93); C734(1.19); C773(1.10)  LDD0557  [10]
 LDCM0241  AC123 HCT 116 C450(1.07); C723(0.88); C734(0.77); C773(1.17)  LDD0558  [10]
 LDCM0242  AC124 HCT 116 C450(1.18); C723(0.90); C734(1.00); C773(1.11)  LDD0559  [10]
 LDCM0243  AC125 HCT 116 C450(1.48); C723(1.03); C734(0.95); C773(1.20)  LDD0560  [10]
 LDCM0244  AC126 HCT 116 C450(1.34); C723(1.14); C734(1.05); C773(1.56)  LDD0561  [10]
 LDCM0245  AC127 HCT 116 C450(1.41); C723(1.14); C734(0.98); C773(1.19)  LDD0562  [10]
 LDCM0246  AC128 HCT 116 C450(1.46); C723(1.21); C734(0.99); C773(0.96)  LDD0563  [10]
 LDCM0247  AC129 HCT 116 C450(1.01); C723(0.84); C734(0.94); C773(0.73)  LDD0564  [10]
 LDCM0249  AC130 HCT 116 C450(1.31); C723(1.11); C734(0.94); C773(0.96)  LDD0566  [10]
 LDCM0250  AC131 HCT 116 C450(1.01); C723(0.97); C734(1.03); C773(0.75)  LDD0567  [10]
 LDCM0251  AC132 HCT 116 C450(1.29); C723(1.02); C734(1.14); C773(0.95)  LDD0568  [10]
 LDCM0252  AC133 HCT 116 C450(1.44); C723(1.07); C734(1.05); C773(0.84)  LDD0569  [10]
 LDCM0253  AC134 HCT 116 C450(1.41); C723(1.21); C734(1.14); C773(1.03)  LDD0570  [10]
 LDCM0254  AC135 HCT 116 C450(1.51); C723(1.14); C734(1.03); C773(0.93)  LDD0571  [10]
 LDCM0255  AC136 HCT 116 C450(1.23); C723(1.20); C734(0.98); C773(0.83)  LDD0572  [10]
 LDCM0256  AC137 HCT 116 C450(1.11); C723(1.07); C734(1.11); C773(0.85)  LDD0573  [10]
 LDCM0257  AC138 HCT 116 C450(1.37); C723(1.26); C734(1.16); C773(0.99)  LDD0574  [10]
 LDCM0258  AC139 HCT 116 C450(1.68); C723(1.26); C734(1.23); C773(1.14)  LDD0575  [10]
 LDCM0259  AC14 HCT 116 C450(1.30); C723(1.10); C734(1.49); C773(1.23)  LDD0576  [10]
 LDCM0260  AC140 HCT 116 C450(1.53); C723(1.26); C734(1.38); C773(1.08)  LDD0577  [10]
 LDCM0261  AC141 HCT 116 C450(1.45); C723(1.19); C734(1.36); C773(0.97)  LDD0578  [10]
 LDCM0262  AC142 HCT 116 C450(1.39); C723(1.01); C734(1.14); C773(0.93)  LDD0579  [10]
 LDCM0263  AC143 HCT 116 C734(0.94); C773(0.94); C911(1.09); C450(1.12)  LDD0580  [10]
 LDCM0264  AC144 HCT 116 C911(0.98); C773(1.00); C734(1.04); C450(1.23)  LDD0581  [10]
 LDCM0265  AC145 HCT 116 C911(0.93); C734(1.06); C450(1.13); C773(1.16)  LDD0582  [10]
 LDCM0266  AC146 HCT 116 C734(0.96); C911(0.98); C773(1.23); C450(1.33)  LDD0583  [10]
 LDCM0267  AC147 HCT 116 C911(0.90); C773(0.92); C734(1.15); C450(1.39)  LDD0584  [10]
 LDCM0268  AC148 HCT 116 C911(0.98); C734(1.20); C773(1.27); C450(1.76)  LDD0585  [10]
 LDCM0269  AC149 HCT 116 C734(1.09); C911(1.14); C773(1.32); C450(1.62)  LDD0586  [10]
 LDCM0270  AC15 HCT 116 C911(0.96); C854(1.05); C855(1.05); C450(1.14)  LDD0587  [10]
 LDCM0271  AC150 HCT 116 C911(0.93); C734(1.00); C450(1.01); C723(1.21)  LDD0588  [10]
 LDCM0272  AC151 HCT 116 C773(0.91); C911(1.02); C734(1.06); C723(1.16)  LDD0589  [10]
 LDCM0273  AC152 HCT 116 C773(0.88); C911(0.93); C734(1.07); C450(1.31)  LDD0590  [10]
 LDCM0274  AC153 HCT 116 C911(1.03); C773(1.34); C734(1.38); C450(2.09)  LDD0591  [10]
 LDCM0621  AC154 HCT 116 C450(1.26); C723(1.40); C734(1.08); C773(1.15)  LDD2158  [10]
 LDCM0622  AC155 HCT 116 C450(1.12); C723(1.36); C734(1.07); C773(1.16)  LDD2159  [10]
 LDCM0623  AC156 HCT 116 C450(0.96); C723(1.00); C734(0.93); C773(1.15)  LDD2160  [10]
 LDCM0624  AC157 HCT 116 C450(1.06); C723(0.93); C734(0.90); C773(1.03)  LDD2161  [10]
 LDCM0276  AC17 HCT 116 C734(0.81); C911(0.96); C450(1.01); C723(1.03)  LDD0593  [10]
 LDCM0277  AC18 HCT 116 C911(0.74); C734(0.94); C450(0.98); C773(1.19)  LDD0594  [10]
 LDCM0278  AC19 HCT 116 C734(0.85); C911(0.93); C450(1.05); C773(1.17)  LDD0595  [10]
 LDCM0279  AC2 HCT 116 C854(0.78); C855(0.78); C450(0.95); C911(1.00)  LDD0596  [10]
 LDCM0280  AC20 HCT 116 C734(0.74); C450(1.04); C723(1.09); C911(1.16)  LDD0597  [10]
 LDCM0281  AC21 HCT 116 C911(0.90); C734(1.01); C723(1.08); C450(1.10)  LDD0598  [10]
 LDCM0282  AC22 HCT 116 C734(0.84); C723(0.93); C911(1.08); C450(1.09)  LDD0599  [10]
 LDCM0283  AC23 HCT 116 C734(0.81); C911(0.94); C773(1.04); C450(1.04)  LDD0600  [10]
 LDCM0284  AC24 HCT 116 C734(0.72); C450(0.91); C723(0.98); C773(1.08)  LDD0601  [10]
 LDCM0285  AC25 HCT 116 C734(0.82); C723(0.92); C773(1.01); C911(1.11)  LDD0602  [10]
 LDCM0286  AC26 HCT 116 C723(0.93); C734(0.97); C773(1.07); C450(1.19)  LDD0603  [10]
 LDCM0287  AC27 HCT 116 C450(0.96); C734(1.04); C911(1.04); C723(1.07)  LDD0604  [10]
 LDCM0288  AC28 HCT 116 C723(1.01); C773(1.20); C450(1.26); C911(1.30)  LDD0605  [10]
 LDCM0289  AC29 HCT 116 C734(1.06); C450(1.13); C723(1.15); C911(1.22)  LDD0606  [10]
 LDCM0290  AC3 HCT 116 C854(0.76); C855(0.76); C911(0.98); C450(1.08)  LDD0607  [10]
 LDCM0291  AC30 HCT 116 C773(1.09); C734(1.23); C723(1.24); C450(1.25)  LDD0608  [10]
 LDCM0292  AC31 HCT 116 C723(0.89); C734(0.96); C773(1.11); C911(1.21)  LDD0609  [10]
 LDCM0293  AC32 HCT 116 C723(0.91); C734(1.04); C911(1.38); C773(1.42)  LDD0610  [10]
 LDCM0294  AC33 HCT 116 C723(0.82); C734(1.11); C450(1.15); C911(1.20)  LDD0611  [10]
 LDCM0295  AC34 HCT 116 C723(0.88); C734(1.10); C450(1.23); C773(1.28)  LDD0612  [10]
 LDCM0296  AC35 HCT 116 C854(0.70); C855(0.70); C450(0.85); C773(0.93)  LDD0613  [10]
 LDCM0297  AC36 HCT 116 C854(0.55); C855(0.55); C450(0.86); C773(0.88)  LDD0614  [10]
 LDCM0298  AC37 HCT 116 C773(0.94); C854(1.09); C855(1.09); C450(1.26)  LDD0615  [10]
 LDCM0299  AC38 HCT 116 C854(0.60); C855(0.60); C773(0.96); C450(1.30)  LDD0616  [10]
 LDCM0300  AC39 HCT 116 C854(0.73); C855(0.73); C450(1.10); C773(1.12)  LDD0617  [10]
 LDCM0301  AC4 HCT 116 C854(0.78); C855(0.78); C911(0.84); C450(1.05)  LDD0618  [10]
 LDCM0302  AC40 HCT 116 C854(0.71); C855(0.71); C773(1.24); C450(1.32)  LDD0619  [10]
 LDCM0303  AC41 HCT 116 C854(0.68); C855(0.68); C773(1.09); C450(1.18)  LDD0620  [10]
 LDCM0304  AC42 HCT 116 C854(0.61); C855(0.61); C773(1.12); C450(1.34)  LDD0621  [10]
 LDCM0305  AC43 HCT 116 C854(0.56); C855(0.56); C773(1.14); C450(1.17)  LDD0622  [10]
 LDCM0306  AC44 HCT 116 C854(0.74); C855(0.74); C773(1.04); C450(1.38)  LDD0623  [10]
 LDCM0307  AC45 HCT 116 C854(0.90); C855(0.90); C773(1.23); C450(1.30)  LDD0624  [10]
 LDCM0308  AC46 HCT 116 C734(0.94); C773(1.36); C450(1.39); C911(1.42)  LDD0625  [10]
 LDCM0309  AC47 HCT 116 C734(1.01); C773(1.17); C450(1.18); C911(1.23)  LDD0626  [10]
 LDCM0310  AC48 HCT 116 C734(0.97); C773(1.09); C911(1.38); C450(1.40)  LDD0627  [10]
 LDCM0311  AC49 HCT 116 C773(1.30); C734(1.44); C450(1.50); C911(1.59)  LDD0628  [10]
 LDCM0312  AC5 HCT 116 C854(0.72); C855(0.72); C911(0.85); C450(0.98)  LDD0629  [10]
 LDCM0313  AC50 HCT 116 C734(1.23); C773(1.35); C911(1.41); C450(1.66)  LDD0630  [10]
 LDCM0314  AC51 HCT 116 C734(0.82); C773(1.17); C450(1.33); C911(1.57)  LDD0631  [10]
 LDCM0315  AC52 HCT 116 C734(0.86); C773(1.04); C450(1.29); C911(1.44)  LDD0632  [10]
 LDCM0316  AC53 HCT 116 C911(1.10); C734(1.11); C450(1.12); C773(1.23)  LDD0633  [10]
 LDCM0317  AC54 HCT 116 C734(1.16); C773(1.21); C450(1.39); C911(1.42)  LDD0634  [10]
 LDCM0318  AC55 HCT 116 C911(1.14); C773(1.15); C734(1.36); C450(1.44)  LDD0635  [10]
 LDCM0319  AC56 HCT 116 C773(1.51); C911(1.57); C450(1.59); C734(1.75)  LDD0636  [10]
 LDCM0320  AC57 HCT 116 C911(0.87); C854(0.88); C855(0.88); C773(0.96)  LDD0637  [10]
 LDCM0321  AC58 HCT 116 C773(0.84); C854(0.93); C855(0.93); C911(1.10)  LDD0638  [10]
 LDCM0322  AC59 HCT 116 C854(0.61); C855(0.61); C911(0.83); C773(0.93)  LDD0639  [10]
 LDCM0323  AC6 HCT 116 C854(1.06); C855(1.06); C911(1.07); C734(1.16)  LDD0640  [10]
 LDCM0324  AC60 HCT 116 C911(0.83); C773(0.91); C854(1.07); C855(1.07)  LDD0641  [10]
 LDCM0325  AC61 HCT 116 C854(0.73); C855(0.73); C911(0.94); C773(0.95)  LDD0642  [10]
 LDCM0326  AC62 HCT 116 C911(0.77); C854(0.85); C855(0.85); C773(0.98)  LDD0643  [10]
 LDCM0327  AC63 HCT 116 C854(0.71); C855(0.71); C911(0.75); C773(0.79)  LDD0644  [10]
 LDCM0328  AC64 HCT 116 C911(0.65); C854(0.86); C855(0.86); C773(1.00)  LDD0645  [10]
 LDCM0329  AC65 HCT 116 C854(0.98); C855(0.98); C773(0.98); C911(1.05)  LDD0646  [10]
 LDCM0330  AC66 HCT 116 C854(0.91); C855(0.91); C773(0.96); C911(1.02)  LDD0647  [10]
 LDCM0331  AC67 HCT 116 C854(0.77); C855(0.77); C911(0.82); C773(0.98)  LDD0648  [10]
 LDCM0332  AC68 HCT 116 C450(1.12); C723(1.14); C773(1.19); C734(1.22)  LDD0649  [10]
 LDCM0333  AC69 HCT 116 C911(1.00); C773(1.10); C723(1.16); C854(1.23)  LDD0650  [10]
 LDCM0334  AC7 HCT 116 C854(0.89); C855(0.89); C911(0.97); C773(1.13)  LDD0651  [10]
 LDCM0335  AC70 HCT 116 C734(0.87); C854(1.16); C855(1.16); C773(1.25)  LDD0652  [10]
 LDCM0336  AC71 HCT 116 C911(0.89); C734(0.98); C723(0.99); C773(1.06)  LDD0653  [10]
 LDCM0337  AC72 HCT 116 C773(0.95); C450(1.12); C723(1.13); C854(1.19)  LDD0654  [10]
 LDCM0338  AC73 HCT 116 C854(1.27); C855(1.27); C773(1.35); C734(1.51)  LDD0655  [10]
 LDCM0339  AC74 HCT 116 C911(0.99); C854(1.00); C855(1.00); C773(1.10)  LDD0656  [10]
 LDCM0340  AC75 HCT 116 C854(1.34); C855(1.34); C911(1.38); C450(1.55)  LDD0657  [10]
 LDCM0341  AC76 HCT 116 C911(0.93); C854(1.11); C855(1.11); C773(1.12)  LDD0658  [10]
 LDCM0342  AC77 HCT 116 C911(1.13); C723(1.27); C854(1.27); C855(1.27)  LDD0659  [10]
 LDCM0343  AC78 HCT 116 C734(1.04); C723(1.08); C773(1.09); C911(1.10)  LDD0660  [10]
 LDCM0344  AC79 HCT 116 C773(1.00); C723(1.14); C911(1.21); C450(1.31)  LDD0661  [10]
 LDCM0345  AC8 HCT 116 C450(1.00); C773(1.03); C854(1.05); C855(1.05)  LDD0662  [10]
 LDCM0346  AC80 HCT 116 C911(0.78); C773(0.91); C734(1.08); C723(1.20)  LDD0663  [10]
 LDCM0347  AC81 HCT 116 C450(0.99); C723(1.00); C773(1.07); C854(1.09)  LDD0664  [10]
 LDCM0348  AC82 HCT 116 C854(1.05); C855(1.05); C911(1.11); C773(1.21)  LDD0665  [10]
 LDCM0349  AC83 HCT 116 C723(1.08); C911(1.23); C734(1.31); C450(1.34)  LDD0666  [10]
 LDCM0350  AC84 HCT 116 C723(1.08); C911(1.15); C450(1.23); C773(1.26)  LDD0667  [10]
 LDCM0351  AC85 HCT 116 C723(0.97); C450(1.08); C773(1.16); C734(1.19)  LDD0668  [10]
 LDCM0352  AC86 HCT 116 C723(1.08); C734(1.14); C773(1.14); C911(1.32)  LDD0669  [10]
 LDCM0353  AC87 HCT 116 C734(1.08); C450(1.09); C911(1.18); C773(1.19)  LDD0670  [10]
 LDCM0354  AC88 HCT 116 C734(1.07); C450(1.14); C773(1.15); C723(1.31)  LDD0671  [10]
 LDCM0355  AC89 HCT 116 C723(0.99); C734(1.21); C773(1.31); C450(1.35)  LDD0672  [10]
 LDCM0357  AC90 HCT 116 C723(1.01); C773(1.04); C734(1.08); C450(1.24)  LDD0674  [10]
 LDCM0358  AC91 HCT 116 C723(0.77); C911(0.97); C773(1.29); C450(1.40)  LDD0675  [10]
 LDCM0359  AC92 HCT 116 C723(1.01); C911(1.19); C773(1.20); C734(1.30)  LDD0676  [10]
 LDCM0360  AC93 HCT 116 C450(1.08); C723(1.10); C773(1.11); C734(1.19)  LDD0677  [10]
 LDCM0361  AC94 HCT 116 C723(0.76); C911(0.87); C773(1.09); C734(1.10)  LDD0678  [10]
 LDCM0362  AC95 HCT 116 C734(1.05); C773(1.07); C723(1.20); C911(1.23)  LDD0679  [10]
 LDCM0363  AC96 HCT 116 C723(0.81); C911(0.99); C773(1.09); C734(1.16)  LDD0680  [10]
 LDCM0364  AC97 HCT 116 C723(1.10); C773(1.19); C450(1.31); C734(1.38)  LDD0681  [10]
 LDCM0365  AC98 HCT 116 C734(0.92); C773(1.26); C911(1.32); C450(1.39)  LDD0682  [10]
 LDCM0366  AC99 HCT 116 C734(0.69); C450(0.91); C773(0.91); C723(0.96)  LDD0683  [10]
 LDCM0248  AKOS034007472 HCT 116 C450(1.19); C723(1.01); C734(1.23); C773(1.17)  LDD0565  [10]
 LDCM0356  AKOS034007680 HCT 116 C911(0.88); C854(0.96); C855(0.96); C723(1.04)  LDD0673  [10]
 LDCM0275  AKOS034007705 HCT 116 C911(1.22); C734(1.23); C450(1.36); C854(1.47)  LDD0592  [10]
 LDCM0156  Aniline NCI-H1299 11.45  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C723(1.08); C773(0.95)  LDD0078  [10]
 LDCM0102  BDHI 8 Jurkat C683(31.33); C695(31.33); CAmbiguous(8.48)  LDD0204  [28]
 LDCM0498  BS-3668 MDA-MB-231 C723(0.74)  LDD2091  [5]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [21]
 LDCM0632  CL-Sc Hep-G2 C911(2.51); C911(1.11)  LDD2227  [14]
 LDCM0367  CL1 HCT 116 C854(0.62); C855(0.62); C450(0.87); C723(1.00)  LDD0684  [10]
 LDCM0368  CL10 HCT 116 C723(0.82); C854(0.87); C855(0.87); C734(1.09)  LDD0685  [10]
 LDCM0369  CL100 HCT 116 C854(0.80); C855(0.80); C911(0.85); C450(0.91)  LDD0686  [10]
 LDCM0370  CL101 HCT 116 C854(0.99); C855(0.99); C911(1.05); C773(1.14)  LDD0687  [10]
 LDCM0371  CL102 HCT 116 C911(0.90); C723(0.90); C854(0.91); C855(0.91)  LDD0688  [10]
 LDCM0372  CL103 HCT 116 C911(0.90); C854(1.03); C855(1.03); C723(1.06)  LDD0689  [10]
 LDCM0373  CL104 HCT 116 C911(0.93); C854(0.99); C855(0.99); C450(1.07)  LDD0690  [10]
 LDCM0374  CL105 HCT 116 C911(0.75); C773(1.02); C734(1.07); C450(1.10)  LDD0691  [10]
 LDCM0375  CL106 HCT 116 C911(0.66); C734(0.95); C450(1.19); C773(1.28)  LDD0692  [10]
 LDCM0376  CL107 HCT 116 C911(0.68); C734(0.98); C773(1.15); C450(1.30)  LDD0693  [10]
 LDCM0377  CL108 HCT 116 C911(0.74); C734(1.11); C450(1.17); C773(1.29)  LDD0694  [10]
 LDCM0378  CL109 HCT 116 C734(0.88); C911(0.92); C773(1.05); C450(1.16)  LDD0695  [10]
 LDCM0379  CL11 HCT 116 C723(0.87); C911(0.94); C734(0.95); C854(1.12)  LDD0696  [10]
 LDCM0380  CL110 HCT 116 C734(0.90); C911(1.01); C450(1.24); C773(1.28)  LDD0697  [10]
 LDCM0381  CL111 HCT 116 C911(1.04); C450(1.06); C734(1.14); C723(1.32)  LDD0698  [10]
 LDCM0382  CL112 HCT 116 C773(0.96); C723(0.98); C450(1.00); C734(1.02)  LDD0699  [10]
 LDCM0383  CL113 HCT 116 C723(0.80); C734(1.01); C911(1.14); C450(1.14)  LDD0700  [10]
 LDCM0384  CL114 HCT 116 C723(0.95); C734(1.04); C773(1.11); C450(1.26)  LDD0701  [10]
 LDCM0385  CL115 HCT 116 C723(1.05); C450(1.10); C773(1.15); C734(1.37)  LDD0702  [10]
 LDCM0386  CL116 HCT 116 C723(0.86); C773(1.08); C734(1.11); C450(1.16)  LDD0703  [10]
 LDCM0387  CL117 HCT 116 C450(1.11); C854(1.24); C855(1.24); C773(1.29)  LDD0704  [10]
 LDCM0388  CL118 HCT 116 C450(0.85); C854(0.91); C855(0.91); C773(1.05)  LDD0705  [10]
 LDCM0389  CL119 HCT 116 C854(0.75); C855(0.75); C773(1.12); C450(2.28)  LDD0706  [10]
 LDCM0390  CL12 HCT 116 C723(0.82); C854(1.01); C855(1.01); C911(1.03)  LDD0707  [10]
 LDCM0391  CL120 HCT 116 C854(0.63); C855(0.63); C450(1.10); C773(1.25)  LDD0708  [10]
 LDCM0392  CL121 HCT 116 C773(1.06); C450(1.08); C911(1.13); C734(1.36)  LDD0709  [10]
 LDCM0393  CL122 HCT 116 C734(1.02); C911(1.23); C773(1.27); C450(1.38)  LDD0710  [10]
 LDCM0394  CL123 HCT 116 C773(1.09); C450(1.17); C911(1.18); C734(1.28)  LDD0711  [10]
 LDCM0395  CL124 HCT 116 C734(1.25); C773(1.26); C911(1.42); C450(1.62)  LDD0712  [10]
 LDCM0396  CL125 HCT 116 C773(0.75); C854(0.80); C855(0.80); C734(0.95)  LDD0713  [10]
 LDCM0397  CL126 HCT 116 C854(0.57); C855(0.57); C773(0.64); C723(0.88)  LDD0714  [10]
 LDCM0398  CL127 HCT 116 C854(0.63); C855(0.63); C773(0.84); C450(0.92)  LDD0715  [10]
 LDCM0399  CL128 HCT 116 C854(0.81); C855(0.81); C773(0.92); C911(0.95)  LDD0716  [10]
 LDCM0400  CL13 HCT 116 C723(0.76); C734(0.86); C854(1.21); C855(1.21)  LDD0717  [10]
 LDCM0401  CL14 HCT 116 C854(0.67); C855(0.67); C723(0.87); C734(0.94)  LDD0718  [10]
 LDCM0402  CL15 HCT 116 C734(0.78); C723(0.80); C854(0.81); C855(0.81)  LDD0719  [10]
 LDCM0403  CL16 HCT 116 C911(0.92); C723(0.98); C773(1.04); C734(1.08)  LDD0720  [10]
 LDCM0404  CL17 HCT 116 C773(0.81); C450(0.91); C723(0.97); C734(1.05)  LDD0721  [10]
 LDCM0405  CL18 HCT 116 C723(0.86); C773(0.90); C734(1.00); C450(1.06)  LDD0722  [10]
 LDCM0406  CL19 HCT 116 C773(0.93); C450(0.95); C723(1.03); C911(1.15)  LDD0723  [10]
 LDCM0407  CL2 HCT 116 C854(0.47); C855(0.47); C734(0.89); C450(0.96)  LDD0724  [10]
 LDCM0408  CL20 HCT 116 C450(1.03); C734(1.11); C723(1.15); C773(1.23)  LDD0725  [10]
 LDCM0409  CL21 HCT 116 C450(0.95); C734(1.04); C773(1.10); C723(1.29)  LDD0726  [10]
 LDCM0410  CL22 HCT 116 C773(0.85); C450(0.97); C734(1.17); C911(1.41)  LDD0727  [10]
 LDCM0411  CL23 HCT 116 C734(0.94); C773(0.97); C450(1.07); C723(1.13)  LDD0728  [10]
 LDCM0412  CL24 HCT 116 C773(0.91); C911(1.15); C450(1.18); C723(1.22)  LDD0729  [10]
 LDCM0413  CL25 HCT 116 C450(1.06); C723(1.23); C734(1.29); C773(0.79)  LDD0730  [10]
 LDCM0414  CL26 HCT 116 C450(1.05); C723(0.92); C734(1.19); C773(0.92)  LDD0731  [10]
 LDCM0415  CL27 HCT 116 C450(1.05); C723(1.02); C734(1.04); C773(1.08)  LDD0732  [10]
 LDCM0416  CL28 HCT 116 C450(1.19); C723(1.10); C734(1.14); C773(0.85)  LDD0733  [10]
 LDCM0417  CL29 HCT 116 C450(1.24); C723(1.17); C734(1.10); C773(0.84)  LDD0734  [10]
 LDCM0418  CL3 HCT 116 C450(0.99); C723(0.97); C734(0.93); C773(1.20)  LDD0735  [10]
 LDCM0419  CL30 HCT 116 C450(1.24); C723(0.98); C734(1.21); C773(0.90)  LDD0736  [10]
 LDCM0420  CL31 HCT 116 C450(0.97); C723(1.24); C773(0.98); C911(1.08)  LDD0737  [10]
 LDCM0421  CL32 HCT 116 C450(1.13); C723(1.14); C734(1.07); C773(1.01)  LDD0738  [10]
 LDCM0422  CL33 HCT 116 C450(1.08); C723(1.00); C734(0.98); C773(1.09)  LDD0739  [10]
 LDCM0423  CL34 HCT 116 C450(1.20); C723(2.03); C734(1.04); C773(1.12)  LDD0740  [10]
 LDCM0424  CL35 HCT 116 C450(1.25); C723(1.51); C734(0.98); C773(1.06)  LDD0741  [10]
 LDCM0425  CL36 HCT 116 C450(1.09); C723(1.50); C734(0.98); C773(0.99)  LDD0742  [10]
 LDCM0426  CL37 HCT 116 C450(1.22); C723(1.86); C734(1.14); C773(1.05)  LDD0743  [10]
 LDCM0428  CL39 HCT 116 C450(1.19); C723(1.69); C734(1.11); C773(1.13)  LDD0745  [10]
 LDCM0429  CL4 HCT 116 C450(1.00); C723(0.95); C734(1.01); C773(1.31)  LDD0746  [10]
 LDCM0430  CL40 HCT 116 C450(1.28); C723(1.30); C734(1.16); C773(0.97)  LDD0747  [10]
 LDCM0431  CL41 HCT 116 C450(1.14); C723(1.54); C734(0.88); C773(0.91)  LDD0748  [10]
 LDCM0432  CL42 HCT 116 C450(1.41); C723(2.23); C734(0.95); C773(0.93)  LDD0749  [10]
 LDCM0433  CL43 HCT 116 C450(1.26); C723(1.82); C734(1.01); C773(1.05)  LDD0750  [10]
 LDCM0434  CL44 HCT 116 C450(1.17); C723(1.40); C734(0.90); C773(1.03)  LDD0751  [10]
 LDCM0435  CL45 HCT 116 C450(1.22); C723(1.86); C734(0.90); C773(1.11)  LDD0752  [10]
 LDCM0436  CL46 HCT 116 C450(0.98); C723(0.77); C734(1.01); C773(0.73)  LDD0753  [10]
 LDCM0437  CL47 HCT 116 C450(0.91); C723(0.84); C734(1.69); C773(0.83)  LDD0754  [10]
 LDCM0438  CL48 HCT 116 C450(0.90); C723(0.75); C734(1.58); C773(0.64)  LDD0755  [10]
 LDCM0439  CL49 HCT 116 C450(1.06); C723(0.92); C734(0.96); C773(0.86)  LDD0756  [10]
 LDCM0440  CL5 HCT 116 C450(1.03); C723(0.79); C734(0.93); C773(1.28)  LDD0757  [10]
 LDCM0441  CL50 HCT 116 C450(0.98); C723(0.82); C734(1.34); C773(0.76)  LDD0758  [10]
 LDCM0442  CL51 HCT 116 C450(1.10); C723(0.90); C734(1.24); C773(1.02)  LDD0759  [10]
 LDCM0443  CL52 HCT 116 C450(1.01); C723(0.79); C734(1.60); C773(0.95)  LDD0760  [10]
 LDCM0444  CL53 HCT 116 C450(0.96); C723(0.77); C734(1.51); C773(0.84)  LDD0761  [10]
 LDCM0445  CL54 HCT 116 C450(0.98); C723(0.78); C734(1.42); C773(0.73)  LDD0762  [10]
 LDCM0446  CL55 HCT 116 C450(0.90); C723(0.78); C734(1.23); C773(0.68)  LDD0763  [10]
 LDCM0447  CL56 HCT 116 C450(0.91); C723(0.99); C734(1.29); C773(0.79)  LDD0764  [10]
 LDCM0448  CL57 HCT 116 C450(0.97); C723(0.81); C734(1.52); C773(0.74)  LDD0765  [10]
 LDCM0449  CL58 HCT 116 C450(0.94); C723(0.80); C734(1.01); C773(0.79)  LDD0766  [10]
 LDCM0450  CL59 HCT 116 C450(0.98); C723(1.00); C734(1.13); C773(0.75)  LDD0767  [10]
 LDCM0451  CL6 HCT 116 C450(1.04); C723(0.92); C734(0.93); C773(1.89)  LDD0768  [10]
 LDCM0452  CL60 HCT 116 C450(0.94); C723(0.94); C734(1.69); C773(0.83)  LDD0769  [10]
 LDCM0453  CL61 HCT 116 C450(1.15); C723(1.04); C773(0.92); C854(1.31)  LDD0770  [10]
 LDCM0454  CL62 HCT 116 C450(1.11); C723(1.13); C773(1.04); C854(1.11)  LDD0771  [10]
 LDCM0455  CL63 HCT 116 C450(1.21); C723(1.23); C773(1.00); C854(1.73)  LDD0772  [10]
 LDCM0456  CL64 HCT 116 C450(1.17); C723(1.20); C773(1.07); C854(1.34)  LDD0773  [10]
 LDCM0457  CL65 HCT 116 C450(1.26); C723(1.11); C773(1.06); C854(1.46)  LDD0774  [10]
 LDCM0458  CL66 HCT 116 C450(1.48); C723(1.47); C773(1.07); C854(1.25)  LDD0775  [10]
 LDCM0459  CL67 HCT 116 C450(1.20); C723(1.38); C773(0.95); C854(1.12)  LDD0776  [10]
 LDCM0460  CL68 HCT 116 C450(1.23); C723(1.17); C773(1.03); C854(1.30)  LDD0777  [10]
 LDCM0461  CL69 HCT 116 C450(1.13); C723(1.09); C773(1.06); C854(1.00)  LDD0778  [10]
 LDCM0462  CL7 HCT 116 C450(1.23); C723(0.75); C734(0.97); C773(1.50)  LDD0779  [10]
 LDCM0463  CL70 HCT 116 C450(1.30); C723(1.12); C773(1.16); C854(1.58)  LDD0780  [10]
 LDCM0464  CL71 HCT 116 C450(1.23); C723(1.20); C773(1.01); C854(1.82)  LDD0781  [10]
 LDCM0465  CL72 HCT 116 C450(1.13); C723(1.05); C773(0.89); C854(1.11)  LDD0782  [10]
 LDCM0466  CL73 HCT 116 C450(1.12); C723(1.12); C773(0.92); C854(0.89)  LDD0783  [10]
 LDCM0467  CL74 HCT 116 C450(1.17); C723(1.23); C773(1.10); C854(1.33)  LDD0784  [10]
 LDCM0469  CL76 HCT 116 C450(0.97); C734(1.14); C773(0.88); C911(0.98)  LDD0786  [10]
 LDCM0470  CL77 HCT 116 C450(0.89); C734(0.98); C773(1.37); C911(1.13)  LDD0787  [10]
 LDCM0471  CL78 HCT 116 C450(0.99); C734(1.12); C773(1.11); C911(1.02)  LDD0788  [10]
 LDCM0472  CL79 HCT 116 C450(1.24); C734(1.02); C773(1.03); C911(1.10)  LDD0789  [10]
 LDCM0473  CL8 HCT 116 C450(1.21); C723(1.05); C734(1.00); C773(1.36)  LDD0790  [10]
 LDCM0474  CL80 HCT 116 C450(1.05); C734(1.06); C773(1.06); C911(0.88)  LDD0791  [10]
 LDCM0475  CL81 HCT 116 C450(1.21); C734(1.01); C773(1.15); C911(1.08)  LDD0792  [10]
 LDCM0476  CL82 HCT 116 C450(1.38); C734(1.06); C773(0.89); C911(0.79)  LDD0793  [10]
 LDCM0477  CL83 HCT 116 C450(1.23); C734(1.19); C773(0.95); C911(1.03)  LDD0794  [10]
 LDCM0478  CL84 HCT 116 C450(1.54); C734(1.05); C773(1.17); C911(1.06)  LDD0795  [10]
 LDCM0479  CL85 HCT 116 C450(1.12); C734(1.09); C773(1.11); C911(1.03)  LDD0796  [10]
 LDCM0480  CL86 HCT 116 C450(1.02); C734(1.00); C773(0.93); C911(0.98)  LDD0797  [10]
 LDCM0481  CL87 HCT 116 C450(1.11); C734(1.27); C773(1.09); C911(0.94)  LDD0798  [10]
 LDCM0482  CL88 HCT 116 C450(1.31); C734(1.07); C773(1.10); C911(0.91)  LDD0799  [10]
 LDCM0483  CL89 HCT 116 C450(1.63); C734(1.00); C773(1.25); C911(0.88)  LDD0800  [10]
 LDCM0484  CL9 HCT 116 C450(1.17); C723(0.86); C734(0.99); C773(1.27)  LDD0801  [10]
 LDCM0485  CL90 HCT 116 C450(0.90); C734(1.00); C773(1.00); C911(1.22)  LDD0802  [10]
 LDCM0486  CL91 HCT 116 C450(1.02); C734(1.29); C773(1.16); C854(0.94)  LDD0803  [10]
 LDCM0487  CL92 HCT 116 C450(0.79); C734(1.00); C773(1.03); C854(0.77)  LDD0804  [10]
 LDCM0488  CL93 HCT 116 C450(1.04); C734(1.16); C773(0.96); C854(0.82)  LDD0805  [10]
 LDCM0489  CL94 HCT 116 C450(0.84); C734(1.68); C773(0.89); C854(0.93)  LDD0806  [10]
 LDCM0490  CL95 HCT 116 C450(0.93); C734(1.17); C773(0.89); C854(0.78)  LDD0807  [10]
 LDCM0491  CL96 HCT 116 C450(0.98); C734(1.25); C773(1.07); C854(0.95)  LDD0808  [10]
 LDCM0492  CL97 HCT 116 C450(0.85); C734(1.61); C773(1.06); C854(0.85)  LDD0809  [10]
 LDCM0493  CL98 HCT 116 C450(0.98); C734(1.39); C773(1.33); C854(0.75)  LDD0810  [10]
 LDCM0494  CL99 HCT 116 C450(0.93); C734(1.20); C773(1.18); C854(0.85)  LDD0811  [10]
 LDCM0634  CY-0357 Hep-G2 C723(1.00)  LDD2228  [14]
 LDCM0495  E2913 HEK-293T C819(0.87); C450(1.10); C25(0.94); C773(0.94)  LDD1698  [29]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C911(2.42); C723(1.20)  LDD1702  [5]
 LDCM0031  Epigallocatechin gallate HEK-293T 9.88  LDD0183  [6]
 LDCM0625  F8 Ramos C773(1.57); C911(1.12)  LDD2187  [30]
 LDCM0572  Fragment10 Ramos C773(1.04)  LDD2189  [30]
 LDCM0573  Fragment11 Ramos C773(0.78); C911(2.14); C819(20.00)  LDD2190  [30]
 LDCM0574  Fragment12 Ramos C773(0.99); C911(0.97); C819(0.74)  LDD2191  [30]
 LDCM0575  Fragment13 Ramos C773(1.05); C911(0.76)  LDD2192  [30]
 LDCM0576  Fragment14 Ramos C773(1.42); C911(1.28); C819(0.26)  LDD2193  [30]
 LDCM0579  Fragment20 Ramos C773(1.13); C911(1.30); C819(0.76)  LDD2194  [30]
 LDCM0580  Fragment21 Ramos C773(1.25); C911(0.63); C819(0.61)  LDD2195  [30]
 LDCM0582  Fragment23 Ramos C773(1.28); C819(0.57)  LDD2196  [30]
 LDCM0578  Fragment27 Ramos C773(1.22); C911(0.91)  LDD2197  [30]
 LDCM0586  Fragment28 Ramos C773(0.75); C911(0.64)  LDD2198  [30]
 LDCM0588  Fragment30 Ramos C773(1.10); C911(0.63)  LDD2199  [30]
 LDCM0589  Fragment31 Ramos C773(1.13); C911(0.88)  LDD2200  [30]
 LDCM0590  Fragment32 Ramos C773(1.07); C911(1.05)  LDD2201  [30]
 LDCM0468  Fragment33 HCT 116 C450(1.32); C723(1.20); C773(1.00); C854(1.50)  LDD0785  [10]
 LDCM0596  Fragment38 Ramos C773(0.97); C911(0.81); C819(0.63)  LDD2203  [30]
 LDCM0566  Fragment4 Ramos C773(1.20); C911(0.90)  LDD2184  [30]
 LDCM0427  Fragment51 HCT 116 C450(1.39); C723(2.17); C734(1.02); C773(0.84)  LDD0744  [10]
 LDCM0610  Fragment52 Ramos C773(1.23); C911(0.84)  LDD2204  [30]
 LDCM0614  Fragment56 Ramos C773(1.21); C911(1.11)  LDD2205  [30]
 LDCM0569  Fragment7 Ramos C773(2.83); C911(1.50)  LDD2186  [30]
 LDCM0571  Fragment9 Ramos C773(0.96); C819(1.15)  LDD2188  [30]
 LDCM0022  KB02 HCT 116 C854(4.21); C855(4.21); C704(3.57); C911(2.52)  LDD0080  [10]
 LDCM0023  KB03 HCT 116 C854(6.73); C855(6.73); C704(5.40); C911(1.65)  LDD0081  [10]
 LDCM0024  KB05 HCT 116 C854(10.06); C855(10.06); C704(4.34); C911(1.48)  LDD0082  [10]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C723(1.41)  LDD2121  [5]
 LDCM0109  NEM HeLa N.A.  LDD0224  [21]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C723(0.95)  LDD2092  [5]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C723(1.42)  LDD2093  [5]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C723(0.62); C819(0.27)  LDD2096  [5]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C723(0.82); C819(0.99)  LDD2098  [5]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C723(0.95)  LDD2099  [5]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C819(0.28)  LDD2106  [5]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C723(0.83); C734(1.30)  LDD2107  [5]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C819(0.36)  LDD2108  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C723(1.06)  LDD2109  [5]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C819(0.62)  LDD2110  [5]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C723(0.98)  LDD2111  [5]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C819(0.42)  LDD2114  [5]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C819(0.47)  LDD2116  [5]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C819(0.61)  LDD2118  [5]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C734(0.50)  LDD2119  [5]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C819(1.07)  LDD2120  [5]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C734(1.43)  LDD2123  [5]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C819(0.39)  LDD2124  [5]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C723(0.82); C819(0.93)  LDD2125  [5]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C819(0.28)  LDD2126  [5]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C819(1.00)  LDD2128  [5]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C723(0.80)  LDD2135  [5]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C723(0.91)  LDD2137  [5]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C723(1.29)  LDD1700  [5]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C723(1.42)  LDD2140  [5]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C723(1.10)  LDD2144  [5]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C723(0.64); C819(0.84)  LDD2146  [5]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C819(0.43)  LDD2148  [5]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C819(0.51)  LDD2149  [5]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C723(0.74)  LDD2150  [5]
 LDCM0032  Oleacein HEK-293T 5.43  LDD0184  [6]
 LDCM0029  Quercetin HEK-293T 4.27  LDD0181  [6]
 LDCM0131  RA190 MM1.R 2.39  LDD0299  [8]
 LDCM0021  THZ1 HCT 116 C723(1.16); C911(0.94)  LDD2173  [10]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Phase 2
Click To Hide/Show 5 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Arry-520 Small molecular drug D04VWJ
Azd-4877 Small molecular drug D02AAO
Ispinesib Small molecular drug D0PW4N
Ly2523355 Small molecular drug D0W9SL
Sb-743921 Small molecular drug D0U4EU
Phase 1
Click To Hide/Show 3 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Arq 621 Small molecular drug D07BKR
Mk-0731 Small molecular drug D0V2YJ
4sc-205 . D08OPX
Investigative
Click To Hide/Show 11 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Monastrol Small molecular drug D0ZK2G
(1s)-1-cyclopropyl-2-[(2s)-4-(25-difluorophenyl)-2-phenyl-25-dihydro-1h-pyrrol-1-yl]-2-oxoethanamine . DB08244
(2s)-4-(25-difluorophenyl)-n-methyl-2-phenyl-n-piperidin-4-yl-25-dihydro-1h-pyrrole-1-carboxamide . DB08239
(2s)-4-(25-difluorophenyl)-nn-dimethyl-2-phenyl-25-dihydro-1h-pyrrole-1-carboxamide . DB08246
(4r)-4-(3-hydroxyphenyl)-nn78-tetramethyl-34-dihydroisoquinoline-2(1h)-carboxamide . DB07064
(5r)-nn-diethyl-5-methyl-2-[(Thiophen-2-ylcarbonyl)Amino]-4567-tetrahydro-1-benzothiophene-3-carboxamide . DB08033
(5s)-5-(3-aminopropyl)-3-(25-difluorophenyl)-n-ethyl-5-phenyl-45-dihydro-1h-pyrazole-1-carboxamide . DB08250
3-[(5s)-1-acetyl-3-(2-chlorophenyl)-45-dihydro-1h-pyrazol-5-yl]Phenol . DB03996
Filanesib . DB06040
Nn-diethyl-2-[(2-thienylcarbonyl)Amino]-4567-tetrahydro-1-benzothiophene-3-carboxamide . DB08032
[(4r)-4-(3-hydroxyphenyl)-16-dimethyl-2-thioxo-1234-tetrahydropyrimidin-5-yl](Phenyl)Methanone . DB08198

References

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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD043348
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
14 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007570
28 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578