Details of the Probe

General Information of Probe

Probe ID
LDPC0417
Probe Name
C178
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 313.401
Lipid-water partition coefficient (xlogp) 3.71222
Rotatable Bond Count (rotbonds) 11
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C18H23N3O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N(c2c([H])c(C([H])([H])[H])c([H])c([H])c2OC([H])([H])[H])C([H])([H])C([H])([H])[H])N=N1
InChI
InChI=1S/C18H23N3O2/c1-5-7-11-18(19-20-18)12-10-17(22)21(6-2)15-13-14(3)8-9-16(15)23-4/h1,8-9,13H,6-7,10-12H2,2-4H3
InChIKey
SXXFMJXPTGYBJY-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

121 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 19.56  LDD1857 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 16.22  LDD1857 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 20.39  LDD1857 
Acid ceramidase (ASAH1) LDTP05905 27.10  LDD1857 
Acyl-coenzyme A thioesterase 8 (ACOT8) LDTP00415 22.63  LDD1857 
ADP-dependent glucokinase (ADPGK) LDTP11127 36.76  LDD1857 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 34.30  LDD1857 
Alpha-galactosidase A (GLA) LDTP02141 17.88  LDD1857 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 20.11  LDD1857 
Amidophosphoribosyltransferase (PPAT) LDTP05480 19.43  LDD1857 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 17.27  LDD1857 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 16.80  LDD1857 
Beta-galactosidase (GLB1) LDTP02837 39.67  LDD1857 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 15.89  LDD1857 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 22.32  LDD1857 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 31.12  LDD1857 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 22.63  LDD1857 
Catechol O-methyltransferase (COMT) LDTP03145 18.51  LDD1857 
Ceramide synthase 1 (CERS1) LDTP03394 15.24  LDD1857 
Ceramide synthase 2 (CERS2) LDTP10329 16.11  LDD1857 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 17.75  LDD1857 
COP9 signalosome complex subunit 5 (COPS5) LDTP09925 15.45  LDD1857 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 26.54  LDD1857 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 73.01  LDD1857 
Cytochrome b5 type B (CYB5B) LDTP00697 78.79  LDD1857 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 16.11  LDD1857 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 23.92  LDD1857 
Delta(24)-sterol reductase (DHCR24) LDTP06375 17.03  LDD1857 
Deoxyhypusine synthase (DHPS) LDTP04248 18.64  LDD1857 
Dihydrofolate reductase (DHFR) LDTP01769 99.73  LDD1857 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 31.34  LDD1857 
Dual specificity protein phosphatase 9 (DUSP9) LDTP11016 15.35  LDD1857 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 37.27  LDD1857 
E3 ubiquitin-protein ligase RNF139 (RNF139) LDTP09556 17.15  LDD1857 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 22.78  LDD1857 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 16.91  LDD1857 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 31.78  LDD1857 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 27.47  LDD1857 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 41.93  LDD1857 
Ferrochelatase, mitochondrial (FECH) LDTP03198 21.56  LDD1857 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 25.28  LDD1857 
Heme A synthase COX15 (COX15) LDTP07931 48.17  LDD1857 
Heme oxygenase 1 (HMOX1) LDTP02359 99.73  LDD1857 
Heme oxygenase 2 (HMOX2) LDTP03540 72.50  LDD1857 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 15.24  LDD1857 
Histone-lysine N-methyltransferase SETDB1 (SETDB1) LDTP06295 20.97  LDD1857 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 22.63  LDD1857 
Inactive C-alpha-formylglycine-generating enzyme 2 (SUMF2) LDTP09056 15.45  LDD1857 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 46.85  LDD1857 
Kinesin-like protein KIF11 (KIF11) LDTP04519 20.25  LDD1857 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 26.35  LDD1857 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 14.83  LDD1857 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 18.00  LDD1857 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 22.16  LDD1857 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 28.05  LDD1857 
Lysosomal acid phosphatase (ACP2) LDTP02539 20.39  LDD1857 
Lysosomal alpha-glucosidase (GAA) LDTP02486 17.88  LDD1857 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 25.46  LDD1857 
Lysosomal protective protein (CTSA) LDTP02505 17.15  LDD1857 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 65.80  LDD1857 
m7GpppX diphosphatase (DCPS) LDTP10163 17.63  LDD1857 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) LDTP00975 22.94  LDD1857 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 31.12  LDD1857 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 15.45  LDD1857 
Multiple inositol polyphosphate phosphatase 1 (MINPP1) LDTP13678 15.67  LDD1857 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 19.03  LDD1857 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 40.50  LDD1857 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 16.56  LDD1857 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 91.77  LDD1857 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 63.12  LDD1857 
NADPH--cytochrome P450 reductase (POR) LDTP02848 15.35  LDD1857 
Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 15.78  LDD1857 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 23.10  LDD1857 
Obg-like ATPase 1 (OLA1) LDTP12610 19.56  LDD1857 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 66.72  LDD1857 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 14.72  LDD1857 
Patatin-like phospholipase domain-containing protein 6 (PNPLA6) LDTP08617 14.62  LDD1857 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 51.63  LDD1857 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 17.15  LDD1857 
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) LDTP03374 15.78  LDD1857 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 50.91  LDD1857 
PHD finger protein 10 (PHF10) LDTP09568 15.35  LDD1857 
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C) LDTP09355 14.62  LDD1857 
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) LDTP06638 15.89  LDD1857 
Phospholipase A2 group XV (PLA2G15) LDTP09088 17.39  LDD1857 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 16.00  LDD1857 
Plasma membrane calcium-transporting ATPase 1 (ATP2B1) LDTP03024 18.90  LDD1857 
Plasma membrane calcium-transporting ATPase 4 (ATP2B4) LDTP03249 14.72  LDD1857 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 25.81  LDD1857 
Presequence protease, mitochondrial (PITRM1) LDTP07003 19.56  LDD1857 
Prostaglandin reductase 3 (PTGR3) LDTP15422 17.51  LDD1857 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 21.56  LDD1857 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 29.45  LDD1857 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 35.26  LDD1857 
Protein disulfide-isomerase (P4HB) LDTP02188 24.93  LDD1857 
Protein O-GlcNAcase (OGA) LDTP00988 17.03  LDD1857 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 18.51  LDD1857 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 27.28  LDD1857 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 29.86  LDD1857 
Ras-related protein Rab-11B (RAB11B) LDTP06501 17.27  LDD1857 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 71.51  LDD1857 
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) LDTP03592 15.45  LDD1857 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 15.24  LDD1857 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 30.48  LDD1857 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 16.68  LDD1857 
SEC23-interacting protein (SEC23IP) LDTP14311 18.51  LDD1857 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 19.43  LDD1857 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B) LDTP03523 15.56  LDD1857 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 42.22  LDD1857 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 15.03  LDD1857 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 17.75  LDD1857 
Squalene monooxygenase (SQLE) LDTP06142 18.25  LDD1857 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 22.47  LDD1857 
Twinkle mtDNA helicase (TWNK) LDTP10778 26.91  LDD1857 
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) LDTP14189 17.03  LDD1857 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 19.56  LDD1857 
Ufm1-specific protease 2 (UFSP2) LDTP12641 15.56  LDD1857 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 18.00  LDD1857 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 15.45  LDD1857 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 85.04  LDD1857 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 28.44  LDD1857 
------------------------------------------------------------------------------------
⏷ Show the Full List of 121 Enzyme
75 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 15.14  LDD1857 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 33.82  LDD1857 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 19.56  LDD1857 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 14.62  LDD1857 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 26.91  LDD1857 
ATP synthase subunit a (MT-ATP6) LDTP01804 41.07  LDD1857 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 82.71  LDD1857 
BRI3-binding protein (BRI3BP) LDTP15648 61.39  LDD1857 
CMP-sialic acid transporter (SLC35A1) LDTP05116 19.97  LDD1857 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 15.67  LDD1857 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 19.16  LDD1857 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 22.47  LDD1857 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 16.80  LDD1857 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 66.26  LDD1857 
Exocyst complex component 1 (EXOC1) LDTP12661 15.67  LDD1857 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 15.45  LDD1857 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 15.14  LDD1857 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 25.81  LDD1857 
Importin subunit alpha-1 (KPNA2) LDTP04501 30.48  LDD1857 
Integral membrane protein 2C (ITM2C) LDTP12451 19.03  LDD1857 
Lysosome membrane protein 2 (SCARB2) LDTP06034 26.54  LDD1857 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 21.56  LDD1857 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 23.43  LDD1857 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 44.32  LDD1857 
Metaxin-1 (MTX1) LDTP05900 15.35  LDD1857 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 15.67  LDD1857 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 46.53  LDD1857 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 63.12  LDD1857 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 33.13  LDD1857 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1857 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1857 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 99.73  LDD1857 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 36.76  LDD1857 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 15.89  LDD1857 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 19.16  LDD1857 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 15.78  LDD1857 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 49.18  LDD1857 
Mpv17-like protein 2 (MPV17L2) LDTP14952 41.64  LDD1857 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 20.97  LDD1857 
Nuclear pore complex protein Nup88 (NUP88) LDTP10897 32.00  LDD1857 
Nucleoporin NDC1 (NDC1) LDTP11213 20.68  LDD1857 
Occludin (OCLN) LDTP06581 18.38  LDD1857 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 20.11  LDD1857 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 14.72  LDD1857 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 16.91  LDD1857 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 18.38  LDD1857 
Probable mitochondrial glutathione transporter SLC25A40 (SLC25A40) LDTP18053 16.56  LDD1857 
Prosaposin (PSAP) LDTP02215 31.56  LDD1857 
Protein GPR107 (GPR107) LDTP07236 45.57  LDD1857 
Protein GPR108 (GPR108) LDTP12383 31.34  LDD1857 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 16.80  LDD1857 
Protein spinster homolog 1 (SPNS1) LDTP11844 15.03  LDD1857 
Protein tweety homolog 3 (TTYH3) LDTP11615 80.45  LDD1857 
Protein YIPF3 (YIPF3) LDTP11626 27.47  LDD1857 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 26.17  LDD1857 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 18.51  LDD1857 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 23.59  LDD1857 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 52.71  LDD1857 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 15.35  LDD1857 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 46.53  LDD1857 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 27.67  LDD1857 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 27.47  LDD1857 
Stomatin (STOM) LDTP03380 17.88  LDD1857 
Syntaxin-3 (STX3) LDTP05811 18.77  LDD1857 
Tetraspanin-3 (TSPAN3) LDTP16813 97.01  LDD1857 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 18.38  LDD1857 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 56.10  LDD1857 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 19.29  LDD1857 
Transmembrane protein 126A (TMEM126A) LDTP15948 93.05  LDD1857 
Transmembrane protein 199 (TMEM199) LDTP08881 68.12  LDD1857 
Transmembrane protein 59 (TMEM59) LDTP11406 18.25  LDD1857 
Transportin-1 (TNPO1) LDTP09949 15.24  LDD1857 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 68.12  LDD1857 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 49.52  LDD1857 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 22.32  LDD1857 
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⏷ Show the Full List of 75 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DNA polymerase epsilon subunit 4 (POLE4) LDTP12471 16.45  LDD1857 
PHD finger-like domain-containing protein 5A (PHF5A) LDTP08006 16.22  LDD1857 
------------------------------------------------------------------------------------
3 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 14.62  LDD1857 
IgG receptor FcRn large subunit p51 (FCGRT) LDTP04720 91.14  LDD1857 
Leukocyte surface antigen CD47 (CD47) LDTP05572 19.70  LDD1857 
------------------------------------------------------------------------------------
87 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 15.24  LDD1857 
Adapter molecule crk (CRK) LDTP04091 32.45  LDD1857 
AH receptor-interacting protein (AIP) LDTP00202 15.03  LDD1857 
Anaphase-promoting complex subunit 16 (ANAPC16) LDTP10213 14.93  LDD1857 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 31.12  LDD1857 
Apolipoprotein B-100 (APOB) LDTP02013 14.72  LDD1857 
Armadillo repeat-containing protein 10 (ARMC10) LDTP08793 19.43  LDD1857 
Ataxin-10 (ATXN10) LDTP13091 17.51  LDD1857 
Centrin-2 (CETN2) LDTP03926 39.95  LDD1857 
Centromere protein P (CENPP) LDTP07419 29.86  LDD1857 
Collectin-12 (COLEC12) LDTP07031 23.75  LDD1857 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 17.75  LDD1857 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 38.32  LDD1857 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 15.03  LDD1857 
Dynactin subunit 3 (DCTN3) LDTP01359 16.80  LDD1857 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 34.06  LDD1857 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 38.85  LDD1857 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 78.79  LDD1857 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 71.01  LDD1857 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 15.78  LDD1857 
Golgi apparatus protein 1 (GLG1) LDTP09920 21.71  LDD1857 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 26.35  LDD1857 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 15.67  LDD1857 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 14.62  LDD1857 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 14.62  LDD1857 
Integrator complex subunit 14 (INTS14) LDTP15834 18.13  LDD1857 
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA) LDTP01259 15.45  LDD1857 
Large proline-rich protein BAG6 (BAG6) LDTP04094 26.72  LDD1857 
Large ribosomal subunit protein mL46 (MRPL46) LDTP15976 18.25  LDD1857 
LYR motif-containing protein 2 (LYRM2) LDTP18467 14.62  LDD1857 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 19.56  LDD1857 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 16.45  LDD1857 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 19.16  LDD1857 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 18.51  LDD1857 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 42.22  LDD1857 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 26.35  LDD1857 
Neuferricin (CYB5D2) LDTP15623 16.34  LDD1857 
Nucleobindin-1 (NUCB1) LDTP05375 25.28  LDD1857 
Nucleobindin-2 (NUCB2) LDTP05160 67.65  LDD1857 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 17.75  LDD1857 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 16.45  LDD1857 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 23.59  LDD1857 
Optic atrophy 3 protein (OPA3) LDTP16006 52.71  LDD1857 
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) LDTP05981 17.15  LDD1857 
Phosducin-like protein 3 (PDCL3) LDTP11825 46.53  LDD1857 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 69.07  LDD1857 
Polyamine-modulated factor 1 (PMF1) LDTP07508 22.78  LDD1857 
Programmed cell death protein 5 (PDCD5) LDTP00417 25.63  LDD1857 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 16.00  LDD1857 
Protein CEBPZOS (CEBPZOS) LDTP18883 43.41  LDD1857 
Protein FAM114A2 (FAM114A2) LDTP16080 28.05  LDD1857 
Protein FAM162A (FAM162A) LDTP10056 39.12  LDD1857 
Protein FAM177A1 (FAM177A1) LDTP15398 17.88  LDD1857 
Protein flightless-1 homolog (FLII) LDTP05734 19.84  LDD1857 
Protein SYS1 homolog (SYS1) LDTP08796 48.50  LDD1857 
Protein YIF1A (YIF1A) LDTP01494 18.00  LDD1857 
Protein YIF1B (YIF1B) LDTP06948 20.39  LDD1857 
PSME3-interacting protein (PSME3IP1) LDTP11654 21.41  LDD1857 
RAD50-interacting protein 1 (RINT1) LDTP07476 20.53  LDD1857 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 17.27  LDD1857 
Reticulocalbin-2 (RCN2) LDTP06097 24.76  LDD1857 
Reticulon-3 (RTN3) LDTP01522 33.36  LDD1857 
RNA-binding protein 10 (RBM10) LDTP05224 40.50  LDD1857 
RNA-binding protein 3 (RBM3) LDTP05226 16.56  LDD1857 
RNA-binding protein 5 (RBM5) LDTP04527 43.41  LDD1857 
RUS family member 1 (RUSF1) LDTP10357 17.51  LDD1857 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 32.67  LDD1857 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 15.14  LDD1857 
Small integral membrane protein 12 (SMIM12) LDTP19859 15.35  LDD1857 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 15.03  LDD1857 
Spartin (SPART) LDTP08735 16.34  LDD1857 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 15.67  LDD1857 
Synaptogyrin-2 (SYNGR2) LDTP00859 33.59  LDD1857 
Syntaxin-18 (STX18) LDTP13086 41.07  LDD1857 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 20.39  LDD1857 
Tetraspanin-6 (TSPAN6) LDTP14458 32.45  LDD1857 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 23.10  LDD1857 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 23.59  LDD1857 
TraB domain-containing protein (TRABD) LDTP19963 24.42  LDD1857 
Trophoblast glycoprotein (TPBG) LDTP05960 30.48  LDD1857 
U6 snRNA-associated Sm-like protein LSm5 (LSM5) LDTP14080 15.35  LDD1857 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 25.28  LDD1857 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 82.14  LDD1857 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 17.03  LDD1857 
UBX domain-containing protein 4 (UBXN4) LDTP09806 14.72  LDD1857 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 16.91  LDD1857 
Wings apart-like protein homolog (WAPL) LDTP08094 16.11  LDD1857 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1857 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587