Details of the Probe

General Information of Probe

Probe ID
LDPC0258
Probe Name
FFF probe4
Synonyms
SCHEMBL20419339
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 311.4
Lipid-water partition coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C17H17N3OS
IUPAC Name
N-(1-benzothiophen-5-ylmethyl)-3-(3-but-3-ynyldiazirin-3-yl)propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NCC2=CC3=C(C=C2)SC=C3
InChI
InChI=1S/C17H17N3OS/c1-2-3-8-17(19-20-17)9-6-16(21)18-12-13-4-5-15-14(11-13)7-10-22-15/h1,4-5,7,10-11H,3,6,8-9,12H2,(H,18,21)
InChIKey
NAPYCTNPMLSLEK-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

128 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 5.42  LDD0466 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 6.36  LDD0466 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 12.21  LDD0466 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 6.99  LDD0466 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 20.00  LDD0466 
5'-nucleotidase domain-containing protein 3 (NT5DC3) LDTP15290 20.00  LDD0466 
Acyl-coenzyme A diphosphatase NUDT19 (NUDT19) LDTP00150 20.00  LDD0466 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 12.83  LDD0466 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 9.66  LDD0466 
ADP-ribosylation factor 5 (ARF5) LDTP05193 6.72  LDD0466 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 19.61  LDD0466 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 6.73  LDD0481 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 12.01  LDD0466 
Alpha-galactosidase A (GLA) LDTP02141 12.78  LDD0466 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 12.98  LDD0466 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 20.00  LDD0466 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 6.34  LDD0466 
Beta-galactosidase (GLB1) LDTP02837 18.01  LDD0466 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 14.66  LDD0466 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 13.29  LDD0466 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 20.00  LDD0466 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 5.94  LDD0466 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 12.13  LDD0466 
Calcyclin-binding protein (CACYBP) LDTP12163 20.00  LDD0466 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 18.05  LDD0466 
Catechol O-methyltransferase (COMT) LDTP03145 20.00  LDD0466 
Cathepsin B (CTSB) LDTP02223 11.66  LDD0466 
Cathepsin D (CTSD) LDTP02198 16.31  LDD0466 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 18.26  LDD0466 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 12.39  LDD0466 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 13.75  LDD0466 
Cytochrome b5 type B (CYB5B) LDTP00697 20.00  LDD0466 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 15.62  LDD0466 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 20.00  LDD0466 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 5.90  LDD0466 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 16.07  LDD0466 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 17.88  LDD0466 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 13.14  LDD0466 
Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) LDTP04646 6.20  LDD0466 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 18.55  LDD0466 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 20.00  LDD0466 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 10.39  LDD0466 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 13.08  LDD0466 
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) LDTP05369 15.62  LDD0466 
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) LDTP03808 9.36  LDD0466 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 5.00  LDD0466 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 12.50  LDD0466 
Epoxide hydrolase 1 (EPHX1) LDTP02175 19.07  LDD0466 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 5.84  LDD0466 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 5.14  LDD0466 
Ferrochelatase, mitochondrial (FECH) LDTP03198 20.00  LDD0466 
Fumarate hydratase, mitochondrial (FH) LDTP02235 20.00  LDD0466 
Glutathione reductase, mitochondrial (GSR) LDTP01771 20.00  LDD0466 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 13.00  LDD0466 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 5.43  LDD0466 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 6.13  LDD0466 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 19.80  LDD0466 
Haloacid dehalogenase-like hydrolase domain-containing protein 3 (HDHD3) LDTP15879 20.00  LDD0466 
Heme oxygenase 2 (HMOX2) LDTP03540 16.44  LDD0466 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 16.83  LDD0466 
Holocytochrome c-type synthase (HCCS) LDTP04581 10.04  LDD0466 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 5.33  LDD0466 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 20.00  LDD0466 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 6.70  LDD0466 
Insulin-degrading enzyme (IDE) LDTP02743 13.68  LDD0466 
Kinesin-like protein KIF11 (KIF11) LDTP04519 10.31  LDD0466 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 12.30  LDD0466 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 16.62  LDD0466 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 9.77  LDD0466 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 20.00  LDD0466 
Lysosomal alpha-glucosidase (GAA) LDTP02486 15.28  LDD0466 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 12.82  LDD0466 
Lysosomal protective protein (CTSA) LDTP02505 20.00  LDD0466 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 20.00  LDD0466 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 8.16  LDD0466 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 20.00  LDD0466 
Minor histocompatibility antigen H13 (HM13) LDTP09396 20.00  LDD0466 
Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) LDTP06810 14.29  LDD0466 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 9.27  LDD0466 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 14.41  LDD0466 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 12.61  LDD0466 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 13.05  LDD0466 
NADH-cytochrome b5 reductase 3 (CYB5R3) LDTP01770 20.00  LDD0466 
NADPH--cytochrome P450 reductase (POR) LDTP02848 7.27  LDD0466 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 12.68  LDD0466 
Outer mitochondrial transmembrane helix translocase (ATAD1) LDTP09070 14.42  LDD0466 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 20.00  LDD0466 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 20.00  LDD0466 
Phenylalanine--tRNA ligase alpha subunit (FARSA) LDTP13831 20.00  LDD0466 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 12.13  LDD0466 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 20.00  LDD0466 
Pre-mRNA-processing factor 19 (PRPF19) LDTP13623 5.53  LDD0466 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 17.03  LDD0466 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 20.00  LDD0466 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 5.00  LDD0466 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 15.50  LDD0466 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) LDTP05373 10.20  LDD0466 
Prolyl endopeptidase-like (PREPL) LDTP06849 20.00  LDD0466 
Prostaglandin reductase 3 (PTGR3) LDTP15422 20.00  LDD0466 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 20.00  LDD0466 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 20.00  LDD0466 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 14.44  LDD0466 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 13.31  LDD0466 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 20.00  LDD0466 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 5.36  LDD0466 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 20.00  LDD0466 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 12.95  LDD0466 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 14.11  LDD0466 
Ras-related protein Rab-11A (RAB11A) LDTP04992 20.00  LDD0466 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 20.00  LDD0466 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 14.29  LDD0466 
rRNA 2'-O-methyltransferase fibrillarin (FBL) LDTP03155 11.62  LDD0466 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 20.00  LDD0466 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 14.17  LDD0466 
Superoxide dismutase [Mn], mitochondrial (SOD2) LDTP02019 15.02  LDD0466 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 13.97  LDD0466 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 16.11  LDD0466 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 14.54  LDD0466 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 6.94  LDD0466 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 6.42  LDD0466 
Tubulin alpha-8 chain (TUBA8) LDTP12810 6.12  LDD0466 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 20.00  LDD0466 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 5.03  LDD0466 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 14.18  LDD0466 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 13.36  LDD0466 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 15.82  LDD0466 
Vesicle-fusing ATPase (NSF) LDTP04096 8.30  LDD0466 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 12.45  LDD0466 
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⏷ Show the Full List of 128 Enzyme
63 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 17.41  LDD0466 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 11.36  LDD0466 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 8.99  LDD0466 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 8.93  LDD0466 
AP-3 complex subunit delta-1 (AP3D1) LDTP00383 12.65  LDD0466 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 14.28  LDD0466 
BOS complex subunit NCLN (NCLN) LDTP10036 17.25  LDD0466 
Calnexin (CANX) LDTP03405 12.05  LDD0466 
Cystatin-B (CSTB) LDTP02009 6.63  LDD0466 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 11.68  LDD0466 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 7.26  LDD0466 
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) LDTP01301 11.82  LDD0466 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 6.94  LDD0466 
Endophilin-B1 (SH3GLB1) LDTP13953 7.42  LDD0466 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 18.30  LDD0466 
Flotillin-1 (FLOT1) LDTP01366 20.00  LDD0466 
Hemoglobin subunit alpha (HBA1; HBA2) LDTP05084 20.00  LDD0466 
Importin-4 (IPO4) LDTP09515 8.78  LDD0466 
Lysosome membrane protein 2 (SCARB2) LDTP06034 20.00  LDD0466 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 14.82  LDD0466 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 14.95  LDD0466 
Metaxin-1 (MTX1) LDTP05900 20.00  LDD0466 
MICOS complex subunit MIC26 (APOO) LDTP11250 19.49  LDD0466 
MICOS complex subunit MIC60 (IMMT) LDTP06660 12.19  LDD0466 
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 5.19  LDD0466 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 12.53  LDD0466 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 20.00  LDD0481 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 18.58  LDD0466 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 18.47  LDD0466 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 20.00  LDD0466 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.00  LDD0466 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 6.80  LDD0466 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 13.43  LDD0466 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 15.15  LDD0466 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 20.00  LDD0466 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 12.11  LDD0466 
Nucleoporin NDC1 (NDC1) LDTP11213 20.00  LDD0466 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 12.55  LDD0466 
Prohibitin 1 (PHB1) LDTP03717 13.09  LDD0466 
Prosaposin (PSAP) LDTP02215 20.00  LDD0466 
Protein FAM8A1 (FAM8A1) LDTP16190 20.00  LDD0466 
Protein spinster homolog 1 (SPNS1) LDTP11844 20.00  LDD0466 
Proton-activated chloride channel (PACC1) LDTP12042 6.32  LDD0466 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 10.16  LDD0466 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 20.00  LDD0466 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 12.52  LDD0466 
Sideroflexin-1 (SFXN1) LDTP12090 12.73  LDD0466 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 12.32  LDD0466 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 20.00  LDD0466 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 20.00  LDD0466 
Stomatin-like protein 2, mitochondrial (STOML2) LDTP13416 20.00  LDD0481 
Surfeit locus protein 4 (SURF4) LDTP00592 14.09  LDD0466 
T-complex protein 1 subunit delta (CCT4) LDTP04391 5.05  LDD0466 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 18.74  LDD0466 
Translocation protein SEC63 homolog (SEC63) LDTP13243 20.00  LDD0466 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 20.00  LDD0466 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 20.00  LDD0466 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 16.59  LDD0466 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 20.00  LDD0466 
Vesicular integral-membrane protein VIP36 (LMAN2) LDTP05690 8.35  LDD0466 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 20.00  LDD0466 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 19.11  LDD0466 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 16.79  LDD0466 
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⏷ Show the Full List of 63 Transporter and channel
6 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
High mobility group protein B1 (HMGB1) LDTP02343 7.22  LDD0466 
High mobility group protein B2 (HMGB2) LDTP03363 9.99  LDD0466 
Homeobox protein Meis2 (MEIS2) LDTP00425 20.00  LDD0466 
Splicing factor, proline- and glutamine-rich (SFPQ) LDTP03212 12.42  LDD0466 
Y-box-binding protein 3 (YBX3) LDTP02870 20.00  LDD0466 
Zinc finger protein 24 (ZNF24) LDTP02879 20.00  LDD0466 
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⏷ Show the Full List of 6 Transcription factor
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 12.31  LDD0466 
------------------------------------------------------------------------------------
86 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 12.87  LDD0466 
Adapter molecule crk (CRK) LDTP04091 20.00  LDD0466 
Alpha-actinin-4 (ACTN4) LDTP00843 6.11  LDD0466 
Apoptosis inhibitor 5 (API5) LDTP11575 14.75  LDD0466 
Band 4.1-like protein 2 (EPB41L2) LDTP00778 20.00  LDD0466 
BRO1 domain-containing protein BROX (BROX) LDTP07234 7.46  LDD0466 
Calumenin (CALU) LDTP00887 20.00  LDD0466 
Clustered mitochondria protein homolog (CLUH) LDTP14486 14.50  LDD0466 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 20.00  LDD0466 
Dynactin subunit 2 (DCTN2) LDTP05922 10.84  LDD0466 
ELAV-like protein 1 (ELAVL1) LDTP06450 7.79  LDD0466 
Emerin (EMD) LDTP04356 20.00  LDD0466 
Endoplasmic reticulum resident protein 44 (ERP44) LDTP11144 6.05  LDD0466 
Endoplasmin (HSP90B1) LDTP02734 5.21  LDD0466 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 20.00  LDD0466 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 7.90  LDD0466 
Eukaryotic translation initiation factor 3 subunit H (EIF3H) LDTP00620 5.08  LDD0466 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 7.12  LDD0466 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 12.88  LDD0466 
HCLS1-associated protein X-1 (HAX1) LDTP00199 19.88  LDD0466 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 12.99  LDD0466 
Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) LDTP05768 6.02  LDD0466 
Heterogeneous nuclear ribonucleoprotein A1-like 2 (HNRNPA1L2) LDTP17097 5.88  LDD0466 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 6.52  LDD0466 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 5.80  LDD0466 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 13.10  LDD0466 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 6.53  LDD0466 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 15.06  LDD0466 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 6.36  LDD0466 
Histone H2AX (H2AX) LDTP02825 5.16  LDD0466 
Hornerin (HRNR) LDTP08425 20.00  LDD0466 
Interleukin enhancer-binding factor 2 (ILF2) LDTP05688 8.01  LDD0466 
Kinectin (KTN1) LDTP08238 20.00  LDD0466 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 20.00  LDD0466 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 20.00  LDD0466 
Large proline-rich protein BAG6 (BAG6) LDTP04094 17.16  LDD0466 
Large ribosomal subunit protein eL8 (RPL7A) LDTP04990 5.05  LDD0466 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 20.00  LDD0466 
Large ribosomal subunit protein uL24 (RPL26) LDTP04914 6.61  LDD0466 
Matrin-3 (MATR3) LDTP04027 5.35  LDD0466 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 7.36  LDD0466 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 18.69  LDD0466 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 7.84  LDD0466 
Neudesin (NENF) LDTP13630 13.04  LDD0466 
Nicastrin (NCSTN) LDTP09787 13.17  LDD0466 
Nucleobindin-1 (NUCB1) LDTP05375 20.00  LDD0466 
Nucleobindin-2 (NUCB2) LDTP05160 20.00  LDD0466 
Nucleolysin TIAR (TIAL1) LDTP05274 20.00  LDD0466 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 13.35  LDD0466 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 17.58  LDD0466 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 12.12  LDD0466 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 20.00  LDD0466 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 14.59  LDD0466 
Pre-mRNA-splicing factor SPF27 (BCAS2) LDTP01358 20.00  LDD0466 
Prefoldin subunit 3 (VBP1) LDTP04935 6.79  LDD0466 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 6.41  LDD0466 
Prohibitin-2 (PHB2) LDTP10924 14.34  LDD0466 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 20.00  LDD0466 
Protein FAM114A2 (FAM114A2) LDTP16080 20.00  LDD0466 
Protein FAM98A (FAM98A) LDTP09086 6.54  LDD0466 
Protein LYRIC (MTDH) LDTP08224 16.47  LDD0466 
Protein NipSnap homolog 1 (NIPSNAP1) LDTP19912 14.97  LDD0466 
Protein SET (SET) LDTP05277 14.18  LDD0466 
Required for meiotic nuclear division protein 1 homolog (RMND1) LDTP12729 17.90  LDD0466 
Reticulocalbin-1 (RCN1) LDTP06352 20.00  LDD0466 
Reticulocalbin-2 (RCN2) LDTP06097 11.19  LDD0466 
Reticulon-4 (RTN4) LDTP12412 20.00  LDD0466 
Ribonucleoprotein PTB-binding 1 (RAVER1) LDTP15356 20.00  LDD0466 
Ribosomal RNA processing protein 1 homolog B (RRP1B) LDTP06182 18.79  LDD0466 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 12.22  LDD0466 
RNA-binding protein 14 (RBM14) LDTP10684 12.18  LDD0466 
RNA-binding protein 39 (RBM39) LDTP06128 5.35  LDD0466 
Scaffold attachment factor B1 (SAFB) LDTP06385 13.28  LDD0466 
Serine/arginine-rich splicing factor 9 (SRSF9) LDTP05800 7.10  LDD0466 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 18.63  LDD0466 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 6.87  LDD0466 
Tetraspanin-6 (TSPAN6) LDTP14458 20.00  LDD0466 
Transformer-2 protein homolog beta (TRA2B) LDTP05036 14.58  LDD0466 
Transmembrane protein 209 (TMEM209) LDTP18272 17.60  LDD0466 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 20.00  LDD0466 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 20.00  LDD0466 
Tubulin beta-3 chain (TUBB3) LDTP05904 6.57  LDD0466 
Tubulin beta-6 chain (TUBB6) LDTP11233 10.39  LDD0466 
Ubiquilin-1 (UBQLN1) LDTP13626 20.00  LDD0466 
Ubiquitin-ribosomal protein eL40 fusion protein (UBA52) LDTP05034 5.17  LDD0466 
Vimentin (VIM) LDTP02297 13.14  LDD0466 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:200uM; negative probe:200uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD0466 
Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:20uM; negative probe:20uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD0481 
Download The Altas

References

1 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.