Details of the Target

General Information of Target

Target ID LDTP17097
Target Name Heterogeneous nuclear ribonucleoprotein A1-like 2 (HNRNPA1L2)
Gene Name HNRNPA1L2
Gene ID 144983
Synonyms
HNRNPA1L; Heterogeneous nuclear ribonucleoprotein A1-like 2; hnRNP A1-like 2; hnRNP core protein A1-like 2
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MRLHLLLLILLLFSILLSPVRGGLGPAEGHCLNLFGVCRTDVCNIVEDQIGACRRRMKCC
RAWWILMPIPTPLIMSDYQEPLKPNLK
Target Bioclass
Other
Subcellular location
Nucleus
Function Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection.
Uniprot ID
Q32P51
Ensemble ID
ENST00000357495.5
HGNC ID
HGNC:27067

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
AZ-9
 Probe Info  		6.37  LDD2154  [2]
DBIA
 Probe Info  		C43(1.06)  LDD0532  [3]
IA-alkyne
 Probe Info  		C43(0.00); C175(0.00)  LDD0162  [4]
Acrolein
 Probe Info  		C43(0.00); H119(0.00); H156(0.00); H120(0.00)  LDD0217  [5]
Cinnamaldehyde
 Probe Info  		N.A.  LDD0220  [5]
Crotonaldehyde
 Probe Info  		H120(0.00); C43(0.00); H119(0.00); H101(0.00)  LDD0219  [5]
Methacrolein
 Probe Info  		C43(0.00); H120(0.00); H156(0.00); H119(0.00)  LDD0218  [5]
W1
 Probe Info  		N.A.  LDD0236  [1]
NAIA_5
 Probe Info  		N.A.  LDD2223  [6]
HHS-465
 Probe Info  		N.A.  LDD2240  [7]
PAL-AfBPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe11
 Probe Info  		6.02  LDD0471  [8]
FFF probe13
 Probe Info  		8.99  LDD0475  [8]
FFF probe14
 Probe Info  		5.17  LDD0477  [8]
FFF probe2
 Probe Info  		8.59  LDD0463  [8]
FFF probe3
 Probe Info  		8.90  LDD0464  [8]
FFF probe4
 Probe Info  		5.88  LDD0466  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C175(0.82)  LDD1507  [9]
 LDCM0215  AC10 HCT 116 C43(1.06)  LDD0532  [3]
 LDCM0216  AC100 HEK-293T C175(1.21)  LDD0814  [3]
 LDCM0217  AC101 HEK-293T C175(0.98)  LDD0815  [3]
 LDCM0218  AC102 HEK-293T C175(1.20)  LDD0816  [3]
 LDCM0219  AC103 HEK-293T C175(1.29)  LDD0817  [3]
 LDCM0220  AC104 HEK-293T C175(1.20)  LDD0818  [3]
 LDCM0221  AC105 HEK-293T C175(0.98)  LDD0819  [3]
 LDCM0222  AC106 HEK-293T C175(0.93)  LDD0820  [3]
 LDCM0223  AC107 HEK-293T C175(1.09)  LDD0821  [3]
 LDCM0224  AC108 HEK-293T C175(1.02)  LDD0822  [3]
 LDCM0225  AC109 HEK-293T C175(1.09)  LDD0823  [3]
 LDCM0226  AC11 HCT 116 C43(0.98)  LDD0543  [3]
 LDCM0227  AC110 HEK-293T C175(1.79)  LDD0825  [3]
 LDCM0228  AC111 HEK-293T C175(2.29)  LDD0826  [3]
 LDCM0229  AC112 HEK-293T C175(1.81)  LDD0827  [3]
 LDCM0230  AC113 HEK-293T C175(1.00)  LDD0828  [3]
 LDCM0231  AC114 HEK-293T C175(1.02)  LDD0829  [3]
 LDCM0232  AC115 HEK-293T C175(1.08)  LDD0830  [3]
 LDCM0233  AC116 HEK-293T C175(1.39)  LDD0831  [3]
 LDCM0234  AC117 HEK-293T C175(1.23)  LDD0832  [3]
 LDCM0235  AC118 HEK-293T C175(1.29)  LDD0833  [3]
 LDCM0236  AC119 HEK-293T C175(1.32)  LDD0834  [3]
 LDCM0237  AC12 HCT 116 C43(1.11)  LDD0554  [3]
 LDCM0238  AC120 HEK-293T C175(1.34)  LDD0836  [3]
 LDCM0239  AC121 HEK-293T C175(1.37)  LDD0837  [3]
 LDCM0240  AC122 HEK-293T C175(2.13)  LDD0838  [3]
 LDCM0241  AC123 HEK-293T C175(1.94)  LDD0839  [3]
 LDCM0242  AC124 HEK-293T C175(1.30)  LDD0840  [3]
 LDCM0243  AC125 HEK-293T C175(1.83)  LDD0841  [3]
 LDCM0244  AC126 HEK-293T C175(2.35)  LDD0842  [3]
 LDCM0245  AC127 HEK-293T C175(2.59)  LDD0843  [3]
 LDCM0259  AC14 HCT 116 C43(0.99)  LDD0576  [3]
 LDCM0263  AC143 PaTu 8988t C175(0.73)  LDD1142  [3]
 LDCM0264  AC144 PaTu 8988t C175(0.97)  LDD1143  [3]
 LDCM0265  AC145 PaTu 8988t C175(0.83)  LDD1144  [3]
 LDCM0266  AC146 PaTu 8988t C175(0.79)  LDD1145  [3]
 LDCM0267  AC147 PaTu 8988t C175(0.67)  LDD1146  [3]
 LDCM0268  AC148 PaTu 8988t C175(0.55)  LDD1147  [3]
 LDCM0269  AC149 PaTu 8988t C175(0.52)  LDD1148  [3]
 LDCM0270  AC15 HCT 116 C43(1.10)  LDD0587  [3]
 LDCM0271  AC150 PaTu 8988t C175(0.50)  LDD1150  [3]
 LDCM0272  AC151 PaTu 8988t C175(0.09)  LDD1151  [3]
 LDCM0273  AC152 PaTu 8988t C175(0.34)  LDD1152  [3]
 LDCM0274  AC153 PaTu 8988t C175(0.31)  LDD1153  [3]
 LDCM0621  AC154 PaTu 8988t C175(0.24)  LDD2166  [3]
 LDCM0622  AC155 PaTu 8988t C175(0.39)  LDD2167  [3]
 LDCM0623  AC156 PaTu 8988t C175(0.63)  LDD2168  [3]
 LDCM0624  AC157 PaTu 8988t C175(0.33)  LDD2169  [3]
 LDCM0276  AC17 HCT 116 C175(0.81)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C175(0.51)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C175(0.90)  LDD0595  [3]
 LDCM0279  AC2 HEK-293T C175(0.99)  LDD1518  [9]
 LDCM0280  AC20 HCT 116 C175(0.88)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C175(0.81)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C175(0.85)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C175(0.75)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C175(0.92)  LDD0601  [3]
 LDCM0285  AC25 HCT 116 C43(1.10); C175(1.50)  LDD0602  [3]
 LDCM0286  AC26 HCT 116 C175(0.97); C43(0.97)  LDD0603  [3]
 LDCM0287  AC27 HCT 116 C43(0.98); C175(1.09)  LDD0604  [3]
 LDCM0288  AC28 HCT 116 C175(0.81); C43(0.99)  LDD0605  [3]
 LDCM0289  AC29 HCT 116 C43(0.93); C175(0.96)  LDD0606  [3]
 LDCM0290  AC3 HEK-293T C175(0.94)  LDD1529  [9]
 LDCM0291  AC30 HCT 116 C43(0.79); C175(1.08)  LDD0608  [3]
 LDCM0292  AC31 HCT 116 C175(0.87); C43(0.92)  LDD0609  [3]
 LDCM0293  AC32 HCT 116 C175(0.63); C43(0.92)  LDD0610  [3]
 LDCM0294  AC33 HCT 116 C43(0.59); C175(0.96)  LDD0611  [3]
 LDCM0295  AC34 HCT 116 C43(0.49); C175(1.10)  LDD0612  [3]
 LDCM0296  AC35 HCT 116 C43(0.82); C175(1.13)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C43(0.86); C175(1.62)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C43(0.89); C175(1.09)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C43(0.94); C175(1.38)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C43(0.65); C175(1.18)  LDD0617  [3]
 LDCM0301  AC4 HEK-293T C175(0.96)  LDD1540  [9]
 LDCM0302  AC40 HCT 116 C175(0.56); C43(0.79)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C43(0.62); C175(1.04)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C43(0.72); C175(0.81)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C43(0.73); C175(1.09)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C43(0.51); C175(0.72)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C175(0.57); C43(0.63)  LDD0624  [3]
 LDCM0308  AC46 HCT 116 C43(0.83); C175(1.04)  LDD0625  [3]
 LDCM0309  AC47 HCT 116 C43(0.70); C175(1.04)  LDD0626  [3]
 LDCM0310  AC48 HCT 116 C43(0.56); C175(1.91)  LDD0627  [3]
 LDCM0311  AC49 HCT 116 C175(0.36); C43(1.04)  LDD0628  [3]
 LDCM0312  AC5 HEK-293T C175(1.12)  LDD1551  [9]
 LDCM0313  AC50 HCT 116 C175(0.37); C43(1.11)  LDD0630  [3]
 LDCM0314  AC51 HCT 116 C43(1.19); C175(1.55)  LDD0631  [3]
 LDCM0315  AC52 HCT 116 C175(0.89); C43(0.99)  LDD0632  [3]
 LDCM0316  AC53 HCT 116 C175(0.53); C43(0.73)  LDD0633  [3]
 LDCM0317  AC54 HCT 116 C175(0.50); C43(0.83)  LDD0634  [3]
 LDCM0318  AC55 HCT 116 C175(0.29); C43(0.79)  LDD0635  [3]
 LDCM0319  AC56 HCT 116 C175(0.10); C43(0.74)  LDD0636  [3]
 LDCM0320  AC57 HCT 116 C175(1.12)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C175(0.82)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C175(0.72)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C43(0.92)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C175(1.12)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C175(1.32)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C175(0.49)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C175(1.00)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C175(0.61)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C175(0.92)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C175(1.26)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C175(0.19)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C43(0.81)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C43(1.23)  LDD0650  [3]
 LDCM0334  AC7 HCT 116 C43(0.86)  LDD0651  [3]
 LDCM0335  AC70 HCT 116 C43(1.40)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C43(1.78)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C43(1.74)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C43(1.06)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C43(1.30)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C43(1.53)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C43(0.81)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C43(1.30)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C43(1.36)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C43(1.31)  LDD0661  [3]
 LDCM0345  AC8 HCT 116 C43(0.99)  LDD0662  [3]
 LDCM0346  AC80 HCT 116 C43(1.17)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C43(1.11)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C43(1.17)  LDD0665  [3]
 LDCM0349  AC83 HEK-293T C175(0.99)  LDD0947  [3]
 LDCM0350  AC84 HEK-293T C175(1.43)  LDD0948  [3]
 LDCM0351  AC85 HEK-293T C175(1.26)  LDD0949  [3]
 LDCM0352  AC86 HEK-293T C175(1.15)  LDD0950  [3]
 LDCM0353  AC87 HEK-293T C175(1.19)  LDD0951  [3]
 LDCM0354  AC88 HEK-293T C175(1.28)  LDD0952  [3]
 LDCM0355  AC89 HEK-293T C175(1.51)  LDD0953  [3]
 LDCM0357  AC90 HEK-293T C175(1.47)  LDD0955  [3]
 LDCM0358  AC91 HEK-293T C175(1.27)  LDD0956  [3]
 LDCM0359  AC92 HEK-293T C175(1.24)  LDD0957  [3]
 LDCM0360  AC93 HEK-293T C175(1.47)  LDD0958  [3]
 LDCM0361  AC94 HEK-293T C175(1.43)  LDD0959  [3]
 LDCM0362  AC95 HEK-293T C175(1.27)  LDD0960  [3]
 LDCM0363  AC96 HEK-293T C175(1.30)  LDD0961  [3]
 LDCM0364  AC97 HEK-293T C175(3.70)  LDD0962  [3]
 LDCM0365  AC98 HEK-293T C175(1.12)  LDD0963  [3]
 LDCM0366  AC99 HEK-293T C175(0.97)  LDD0964  [3]
 LDCM0248  AKOS034007472 HCT 116 C43(0.98)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C43(0.83)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C43(1.24)  LDD0592  [3]
 LDCM0020  ARS-1620 HCC44 C175(0.94)  LDD2171  [3]
 LDCM0151  AZ-11 HeLa 6.37  LDD2154  [2]
 LDCM0108  Chloroacetamide HeLa C43(0.00); H119(0.00); H120(0.00); H156(0.00)  LDD0222  [5]
 LDCM0367  CL1 HCT 116 C175(1.02)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C175(0.55)  LDD0685  [3]
 LDCM0369  CL100 HEK-293T C175(0.89)  LDD1573  [9]
 LDCM0370  CL101 HCT 116 C43(0.88)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C43(0.85)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C43(1.13)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C43(1.13)  LDD0690  [3]
 LDCM0374  CL105 HCT 116 C175(0.55)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C175(0.56)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C175(0.57)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C175(0.58)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C175(0.64)  LDD0695  [3]
 LDCM0379  CL11 HCT 116 C175(0.44)  LDD0696  [3]
 LDCM0380  CL110 HCT 116 C175(0.56)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C175(0.69)  LDD0698  [3]
 LDCM0382  CL112 HCT 116 C175(0.84); C43(1.00)  LDD0699  [3]
 LDCM0383  CL113 HCT 116 C175(0.67); C43(0.87)  LDD0700  [3]
 LDCM0384  CL114 HCT 116 C175(0.78); C43(1.07)  LDD0701  [3]
 LDCM0385  CL115 HCT 116 C43(0.63); C175(0.83)  LDD0702  [3]
 LDCM0386  CL116 HCT 116 C43(0.74); C175(0.86)  LDD0703  [3]
 LDCM0387  CL117 HCT 116 C175(0.21); C43(0.54)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C175(0.98); C43(1.16)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C175(0.89); C43(0.99)  LDD0706  [3]
 LDCM0390  CL12 HCT 116 C175(0.35)  LDD0707  [3]
 LDCM0391  CL120 HCT 116 C43(0.82); C175(1.22)  LDD0708  [3]
 LDCM0392  CL121 HCT 116 C175(0.50); C43(0.83)  LDD0709  [3]
 LDCM0393  CL122 HCT 116 C175(0.78); C43(0.98)  LDD0710  [3]
 LDCM0394  CL123 HCT 116 C175(0.46); C43(0.75)  LDD0711  [3]
 LDCM0395  CL124 HCT 116 C175(0.38); C43(0.87)  LDD0712  [3]
 LDCM0396  CL125 HCT 116 C175(1.60)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C175(1.23)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C175(1.18)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C175(0.74)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C175(0.80)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C175(0.83)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C175(0.19)  LDD0719  [3]
 LDCM0403  CL16 HCT 116 C43(0.82); C175(0.86)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C43(0.85); C175(0.93)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C175(1.18); C43(1.26)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C43(0.89); C175(0.98)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C175(1.10)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C175(0.49); C43(1.08)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C175(0.43); C43(0.98)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C175(0.13); C43(1.03)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C43(0.63); C175(0.89)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C175(0.43); C43(1.02)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C175(0.54); C43(1.00)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C175(0.80); C43(0.51)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C175(0.86); C43(1.02)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C175(0.63); C43(0.97)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C175(0.59); C43(1.07)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C175(0.99)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C175(0.74); C43(0.97)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C175(0.87); C43(1.27)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C175(1.25); C43(0.85)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C175(0.76); C43(1.06)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C175(0.44); C43(1.07)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C175(0.34); C43(1.32)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C175(0.47); C43(1.27)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C175(0.29); C43(0.73)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C175(0.41); C43(0.93)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C175(0.88)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C175(0.42); C43(1.07)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C175(0.50); C43(1.19)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C175(0.08); C43(1.09)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C175(0.28); C43(1.20)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C175(0.62); C43(1.36)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C175(0.54); C43(1.38)  LDD0752  [3]
 LDCM0436  CL46 HCT 116 C43(1.06)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C43(1.10)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C43(1.01)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C43(0.99)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C175(1.03)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C43(1.13)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C43(1.14)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C43(0.91)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C43(0.45)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C43(0.98)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C43(1.17)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C43(0.99)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C43(1.24)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C43(1.23)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C43(1.16)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C175(0.96)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C43(1.16)  LDD0769  [3]
 LDCM0453  CL61 PaTu 8988t C175(0.97)  LDD1332  [3]
 LDCM0454  CL62 PaTu 8988t C175(0.80)  LDD1333  [3]
 LDCM0455  CL63 PaTu 8988t C175(0.60)  LDD1334  [3]
 LDCM0456  CL64 PaTu 8988t C175(0.59)  LDD1335  [3]
 LDCM0457  CL65 PaTu 8988t C175(0.79)  LDD1336  [3]
 LDCM0458  CL66 PaTu 8988t C175(0.57)  LDD1337  [3]
 LDCM0459  CL67 PaTu 8988t C175(0.75)  LDD1338  [3]
 LDCM0460  CL68 PaTu 8988t C175(0.76)  LDD1339  [3]
 LDCM0461  CL69 PaTu 8988t C175(0.44)  LDD1340  [3]
 LDCM0462  CL7 HCT 116 C175(0.64)  LDD0779  [3]
 LDCM0463  CL70 PaTu 8988t C175(0.85)  LDD1342  [3]
 LDCM0464  CL71 PaTu 8988t C175(0.63)  LDD1343  [3]
 LDCM0465  CL72 PaTu 8988t C175(0.79)  LDD1344  [3]
 LDCM0466  CL73 PaTu 8988t C175(0.49)  LDD1345  [3]
 LDCM0467  CL74 PaTu 8988t C175(0.59)  LDD1346  [3]
 LDCM0469  CL76 HCT 116 C175(0.97); C43(1.11)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C175(0.74); C43(1.09)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C175(0.77); C43(1.05)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C175(0.58); C43(0.63)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C175(0.32)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C175(0.98); C43(1.56)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C175(0.69); C43(1.49)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C175(0.31); C43(2.14)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C175(0.44); C43(1.31)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C175(0.16); C43(0.93)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C175(0.85); C43(1.35)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C175(1.19); C43(1.03)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C175(0.95); C43(1.55)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C175(0.50); C43(1.40)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C175(0.09); C43(1.43)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C175(0.71)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C175(1.27); C43(1.06)  LDD0802  [3]
 LDCM0486  CL91 HEK-293T C175(1.32)  LDD1689  [9]
 LDCM0487  CL92 HEK-293T C175(1.11)  LDD1690  [9]
 LDCM0488  CL93 HEK-293T C175(1.40)  LDD1691  [9]
 LDCM0489  CL94 HEK-293T C175(1.81)  LDD1692  [9]
 LDCM0490  CL95 HEK-293T C175(1.15)  LDD1693  [9]
 LDCM0491  CL96 HEK-293T C175(1.28)  LDD1694  [9]
 LDCM0492  CL97 HEK-293T C175(0.84)  LDD1695  [9]
 LDCM0493  CL98 HEK-293T C175(0.86)  LDD1696  [9]
 LDCM0494  CL99 HEK-293T C175(0.92)  LDD1697  [9]
 LDCM0495  E2913 HEK-293T C175(1.00)  LDD1698  [9]
 LDCM0468  Fragment33 PaTu 8988t C175(0.54)  LDD1347  [3]
 LDCM0427  Fragment51 HCT 116 C175(0.16); C43(1.11)  LDD0744  [3]
 LDCM0107  IAA HeLa C43(0.00); H156(0.00); H119(0.00); H33(0.00)  LDD0221  [5]
 LDCM0022  KB02 HEK-293T C175(0.89)  LDD1492  [9]
 LDCM0023  KB03 HEK-293T C175(1.13)  LDD1497  [9]
 LDCM0024  KB05 COLO792 C64(1.21)  LDD3310  [10]
 LDCM0109  NEM HeLa C43(0.00); H119(0.00); H120(0.00); H156(0.00)  LDD0223  [5]
 LDCM0021  THZ1 HCT 116 C175(0.94)  LDD2173  [3]
 LDCM0113  W17 Hep-G2 E114(0.64)  LDD0240  [1]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
6 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
7 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
8 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840