Probe ID	LDPC0260
Probe Name	FFF probe6
Probe Type	PAL-AfBPP Probe
Structure
	2D MOL
Ro5 Violations (Lipinski): 0	Molecular Weight (mw)		324.384
	Lipid-water partition coefficient (xlogp)		2.8898
	Rotatable Bond Count (rotbonds)		7
	Hydrogen Bond Donor Count (hbonddonor)		1
	Hydrogen Bond Acceptor Count (hbondacc)		4
Chemical Identifiers	Formula C18H20N4O2 Canonical SMILES [H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])c2c([H])c([H])c3c(c2[H])C([H])([H])C([H])([H])C(=O)N3C([H])([H])[H])N=N1 InChI InChI=1S/C18H20N4O2/c1-3-4-10-18(20-21-18)11-9-16(23)19-14-6-7-15-13(12-14)5-8-17(24)22(15)2/h1,6-7,12H,4-5,8-11H2,2H3,(H,19,23) InChIKey VZCFSFRUYNMMJK-UHFFFAOYSA-N

135 Enzyme Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 20.00  LDD0467  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) LDTP07483 12.42  LDD0468  5'-3' exonuclease PLD3 (PLD3) LDTP08476 19.08  LDD0467  5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 20.00  LDD0467  Aconitate hydratase, mitochondrial (ACO2) LDTP10982 20.00  LDD0467  Acyl-coenzyme A diphosphatase NUDT19 (NUDT19) LDTP00150 20.00  LDD0467  Acylglycerol kinase, mitochondrial (AGK) LDTP06905 6.64  LDD0467  Adenosine kinase (ADK) LDTP04689 20.00  LDD0468  Adenosylhomocysteinase 3 (AHCYL2) LDTP10394 14.85  LDD0468  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 15.30  LDD0482  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 20.00  LDD0482  Alpha-adducin (ADD1) LDTP03770 20.00  LDD0482  Alpha-galactosidase A (GLA) LDTP02141 14.20  LDD0482  Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 7.10  LDD0467  Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 20.00  LDD0467  ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 8.80  LDD0467  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 20.00  LDD0468  ATP-dependent DNA/RNA helicase DHX36 (DHX36) LDTP11841 12.36  LDD0467  ATP-dependent RNA helicase DDX3X (DDX3X) LDTP00314 6.69  LDD0482  ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 6.26  LDD0467  ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 11.04  LDD0467  ATPase family AAA domain-containing protein 3C (ATAD3C) LDTP19391 8.70  LDD0467  CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 7.45  LDD0467  Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) LDTP05920 11.01  LDD0468  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 13.04  LDD0467  Catalase (CAT) LDTP02001 20.00  LDD0468  Cathepsin D (CTSD) LDTP02198 6.13  LDD0467  Complex I assembly factor ACAD9, mitochondrial (ACAD9) LDTP12048 7.39  LDD0467  Cyclin-dependent kinase 1 (CDK1) LDTP02149 13.63  LDD0482  Cyclin-G-associated kinase (GAK) LDTP00497 20.00  LDD0468  Cystathionine beta-synthase (CBS) LDTP03753 12.04  LDD0468  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 7.79  LDD0467  Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 20.00  LDD0467  dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 15.99  LDD0482  Delta(14)-sterol reductase LBR (LBR) LDTP06200 5.16  LDD0467  Delta(24)-sterol reductase (DHCR24) LDTP06375 20.00  LDD0482  Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 8.68  LDD0467  Deoxyhypusine hydroxylase (DOHH) LDTP11225 20.00  LDD0468  Deoxyhypusine synthase (DHPS) LDTP04248 13.88  LDD0468  Dermcidin (DCD) LDTP05171 20.00  LDD0468  DNA replication licensing factor MCM4 (MCM4) LDTP03680 7.13  LDD0467  DNA replication licensing factor MCM6 (MCM6) LDTP06150 18.37  LDD0467  DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 9.38  LDD0467  Dolichol kinase (DOLK) LDTP13709 20.00  LDD0467  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 6.54  LDD0467  Dynamin-1 (DNM1) LDTP05447 9.73  LDD0467  Dynamin-2 (DNM2) LDTP04374 10.78  LDD0467  Dynamin-3 (DNM3) LDTP13744 9.46  LDD0467  E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 11.86  LDD0468  E3 ubiquitin-protein ligase TRIM33 (TRIM33) LDTP13702 20.00  LDD0467  Elongation factor Tu, mitochondrial (TUFM) LDTP04251 9.09  LDD0467  Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 5.58  LDD0467  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 12.66  LDD0467  Endothelin-converting enzyme 1 (ECE1) LDTP04008 5.69  LDD0467  Enoyl-CoA delta isomerase 2 (ECI2) LDTP01245 7.24  LDD0467  Epoxide hydrolase 1 (EPHX1) LDTP02175 20.00  LDD0467  Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 12.77  LDD0467  Exonuclease 1 (EXO1) LDTP13751 12.64  LDD0467  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 15.32  LDD0467  Fructosamine-3-kinase (FN3K) LDTP11904 20.00  LDD0468  Glutamate dehydrogenase 1, mitochondrial (GLUD1) LDTP01768 15.05  LDD0467  Glutamate dehydrogenase 2, mitochondrial (GLUD2) LDTP04256 5.89  LDD0468  Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 6.00  LDD0467  Glutathione S-transferase omega-1 (GSTO1) LDTP05128 14.62  LDD0482  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 20.00  LDD0467  Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 9.34  LDD0467  Heme oxygenase 2 (HMOX2) LDTP03540 20.00  LDD0467  Holocytochrome c-type synthase (HCCS) LDTP04581 11.79  LDD0468  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 8.13  LDD0468  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 5.79  LDD0467  Isoleucine--tRNA ligase, mitochondrial (IARS2) LDTP12588 8.48  LDD0467  Kinesin-like protein KIF11 (KIF11) LDTP04519 5.30  LDD0467  Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 20.00  LDD0467  Lon protease homolog, mitochondrial (LONP1) LDTP03817 6.88  LDD0467  Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 12.29  LDD0467  Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 20.00  LDD0482  Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 12.91  LDD0482  Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2) LDTP06796 20.00  LDD0467  Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 20.00  LDD0467  Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 6.48  LDD0467  Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 5.13  LDD0467  Myosin-10 (MYH10) LDTP03765 5.30  LDD0467  NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 20.00  LDD0467  NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 13.39  LDD0468  NAD(P)H-hydrate epimerase (NAXE) LDTP09110 6.12  LDD0467  NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 20.00  LDD0467  Nardilysin (NRDC) LDTP00886 9.74  LDD0467  Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 20.00  LDD0467  Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 6.64  LDD0467  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 13.81  LDD0467  Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 14.75  LDD0467  Plasma alpha-L-fucosidase (FUCA2) LDTP11215 16.43  LDD0467  Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 6.55  LDD0467  Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.00  LDD0467  Presequence protease, mitochondrial (PITRM1) LDTP07003 7.34  LDD0467  Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 15.16  LDD0467  Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 6.71  LDD0468  Prolyl endopeptidase-like (PREPL) LDTP06849 12.51  LDD0467  Prostaglandin reductase 2 (PTGR2) LDTP08979 20.00  LDD0482  Proteasome subunit alpha type-1 (PSMA1) LDTP03330 7.72  LDD0467  Proteasome subunit alpha type-4 (PSMA4) LDTP03333 6.88  LDD0467  Proteasome subunit beta type-1 (PSMB1) LDTP03060 7.05  LDD0482  Proteasome subunit beta type-2 (PSMB2) LDTP04285 8.31  LDD0468  Proteasome subunit beta type-3 (PSMB3) LDTP04284 12.40  LDD0467  Proteasome subunit beta type-4 (PSMB4) LDTP03417 6.04  LDD0468  Proteasome subunit beta type-5 (PSMB5) LDTP03419 15.33  LDD0467  Proteasome subunit beta type-6 (PSMB6) LDTP03418 13.02  LDD0468  Proteasome subunit beta type-7 (PSMB7) LDTP10862 7.48  LDD0468  Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 5.85  LDD0468  Protein O-GlcNAcase (OGA) LDTP00988 5.92  LDD0467  Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 20.00  LDD0468  Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 8.39  LDD0467  RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 5.63  LDD0468  Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) LDTP00751 20.00  LDD0468  Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 11.17  LDD0467  Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 13.91  LDD0467  Ribosomal protein S6 kinase alpha-2 (RPS6KA2) LDTP06363 15.98  LDD0468  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 14.21  LDD0467  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 6.01  LDD0468  S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) LDTP00890 17.03  LDD0467  S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 10.89  LDD0482  Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 5.23  LDD0482  Small ribosomal subunit protein uS3 (RPS3) LDTP03223 5.07  LDD0468  Sodium/potassium-transporting ATPase subunit alpha-3 (ATP1A3) LDTP02671 6.77  LDD0467  Squalene synthase (FDFT1) LDTP03842 20.00  LDD0482  STE20-like serine/threonine-protein kinase (SLK) LDTP11819 5.39  LDD0467  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 9.12  LDD0482  Thioredoxin-like protein 1 (TXNL1) LDTP00758 7.23  LDD0468  Threonine--tRNA ligase, mitochondrial (TARS2) LDTP11319 5.56  LDD0467  Tyrosine-protein kinase BAZ1B (BAZ1B) LDTP13344 7.10  LDD0467  Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 5.83  LDD0468  Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 10.88  LDD0468  UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) LDTP00601 9.02  LDD0467  V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 9.85  LDD0482  Xaa-Pro aminopeptidase 3 (XPNPEP3) LDTP12420 20.00  LDD0468  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 135 Enzyme
53 Transporter and channel Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID 45 kDa calcium-binding protein (SDF4) LDTP11116 20.00  LDD0467  Annexin A2 (ANXA2) LDTP02199 7.49  LDD0482  ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 5.25  LDD0467  BOS complex subunit NCLN (NCLN) LDTP10036 20.00  LDD0467  Calnexin (CANX) LDTP03405 10.13  LDD0467  Calreticulin (CALR) LDTP03402 5.83  LDD0467  Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 20.00  LDD0482  Desmoplakin (DSP) LDTP02815 20.00  LDD0482  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 7.15  LDD0467  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 5.25  LDD0467  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 13.41  LDD0467  ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 20.00  LDD0467  Importin subunit alpha-1 (KPNA2) LDTP04501 5.41  LDD0482  Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 11.26  LDD0467  Metaxin-1 (MTX1) LDTP05900 20.00  LDD0467  MICOS complex subunit MIC60 (IMMT) LDTP06660 17.77  LDD0467  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 8.81  LDD0467  Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 8.34  LDD0467  Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 6.88  LDD0468  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 20.00  LDD0482  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.00  LDD0467  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 6.04  LDD0467  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 12.90  LDD0468  Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 16.31  LDD0467  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 20.00  LDD0467  Mpv17-like protein 2 (MPV17L2) LDTP14952 20.00  LDD0467  Nuclear pore complex protein Nup205 (NUP205) LDTP09825 5.25  LDD0468  Nuclear pore complex protein Nup93 (NUP93) LDTP08769 6.81  LDD0467  Nucleoporin NDC1 (NDC1) LDTP11213 20.00  LDD0467  Nucleoprotein TPR (TPR) LDTP02612 5.02  LDD0467  Oxysterol-binding protein-related protein 8 (OSBPL8) LDTP11531 5.49  LDD0467  PAT complex subunit CCDC47 (CCDC47) LDTP10059 6.23  LDD0467  Prosaposin (PSAP) LDTP02215 10.71  LDD0467  Protein SEC13 homolog (SEC13) LDTP04707 5.07  LDD0467  Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 20.00  LDD0467  Protein wntless homolog (WLS) LDTP07156 9.80  LDD0467  Proton-activated chloride channel (PACC1) LDTP12042 8.66  LDD0467  Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 20.00  LDD0467  Scavenger receptor class B member 1 (SCARB1) LDTP09547 6.12  LDD0467  Sideroflexin-1 (SFXN1) LDTP12090 7.17  LDD0467  Solute carrier family 25 member 3 (SLC25A3) LDTP05238 12.94  LDD0467  Solute carrier family 35 member F2 (SLC35F2) LDTP17641 20.00  LDD0482  Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 20.00  LDD0467  Sorting nexin-2 (SNX2) LDTP01043 9.38  LDD0467  Stomatin-like protein 2, mitochondrial (STOML2) LDTP13416 6.21  LDD0467  Surfeit locus protein 4 (SURF4) LDTP00592 7.45  LDD0467  Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 18.77  LDD0467  Translocation protein SEC63 homolog (SEC63) LDTP13243 7.85  LDD0467  Tubulin beta-1 chain (TUBB1) LDTP11916 6.62  LDD0502  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 6.60  LDD0467  Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 20.00  LDD0467  Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 18.94  LDD0467  Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 5.12  LDD0467  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 53 Transporter and channel
9 Transcription factor Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID Cell division cycle 5-like protein (CDC5L) LDTP10868 5.33  LDD0467  DnaJ homolog subfamily C member 2 (DNAJC2) LDTP10891 8.48  LDD0467  Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 5.62  LDD0467  Paraspeckle component 1 (PSPC1) LDTP09694 13.86  LDD0467  Protein polybromo-1 (PBRM1) LDTP08216 6.56  LDD0467  Signal transducer and activator of transcription 2 (STAT2) LDTP04515 20.00  LDD0468  SWI/SNF complex subunit SMARCC1 (SMARCC1) LDTP09932 5.66  LDD0467  Y-box-binding protein 1 (YBX1) LDTP05065 9.43  LDD0467  Y-box-binding protein 3 (YBX3) LDTP02870 5.79  LDD0468  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 9 Transcription factor
112 Other Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID A-kinase anchor protein 8 (AKAP8) LDTP00880 5.69  LDD0468  A-kinase anchor protein 8-like (AKAP8L) LDTP13591 5.55  LDD0467  Acyl carrier protein, mitochondrial (NDUFAB1) LDTP00372 20.00  LDD0468  Afadin (AFDN) LDTP04679 12.48  LDD0467  Annexin A7 (ANXA7) LDTP03030 6.97  LDD0482  BAG family molecular chaperone regulator 4 (BAG4) LDTP01600 20.00  LDD0468  Bromodomain-containing protein 2 (BRD2) LDTP03322 6.14  LDD0467  BTB/POZ domain-containing protein KCTD12 (KCTD12) LDTP15705 7.92  LDD0467  Calumenin (CALU) LDTP00887 20.00  LDD0467  Centrosomal protein 43 (CEP43) LDTP01652 20.00  LDD0482  Clustered mitochondria protein homolog (CLUH) LDTP14486 11.64  LDD0467  DAZ-associated protein 1 (DAZAP1) LDTP10271 5.07  LDD0468  DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 20.00  LDD0467  Drebrin (DBN1) LDTP06588 5.62  LDD0468  Dynactin subunit 2 (DCTN2) LDTP05922 6.10  LDD0467  Emerin (EMD) LDTP04356 5.34  LDD0467  Endoplasmin (HSP90B1) LDTP02734 5.97  LDD0467  Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 20.00  LDD0482  Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 13.34  LDD0467  Far upstream element-binding protein 1 (FUBP1) LDTP10078 5.80  LDD0467  Far upstream element-binding protein 2 (KHSRP) LDTP09938 6.06  LDD0467  Far upstream element-binding protein 3 (FUBP3) LDTP10408 5.87  LDD0468  FAS-associated factor 2 (FAF2) LDTP10185 12.05  LDD0467  Golgi integral membrane protein 4 (GOLIM4) LDTP00281 17.20  LDD0482  Heat shock protein beta-1 (HSPB1) LDTP02053 5.17  LDD0468  Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 6.31  LDD0482  Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 7.21  LDD0468  Heterogeneous nuclear ribonucleoprotein C-like 1 (HNRNPCL1) LDTP01053 7.67  LDD0482  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 8.57  LDD0468  Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 6.37  LDD0468  Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 5.62  LDD0468  Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 5.20  LDD0467  Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 6.37  LDD0468  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 7.21  LDD0467  Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 5.42  LDD0467  Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 5.48  LDD0467  Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 5.79  LDD0467  Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 7.81  LDD0468  Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 5.14  LDD0467  Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 7.82  LDD0468  Hornerin (HRNR) LDTP08425 20.00  LDD0468  Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) LDTP14272 5.17  LDD0468  Junction plakoglobin (JUP) LDTP02756 12.44  LDD0482  KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) LDTP05525 10.00  LDD0482  Kinectin (KTN1) LDTP08238 9.45  LDD0467  Lamin-B1 (LMNB1) LDTP03065 7.47  LDD0467  Lamin-B2 (LMNB2) LDTP05400 20.00  LDD0467  Large proline-rich protein BAG6 (BAG6) LDTP04094 12.16  LDD0467  Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 20.00  LDD0467  Microtubule-associated protein 4 (MAP4) LDTP03404 12.00  LDD0467  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 20.00  LDD0467  Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 5.04  LDD0467  Negative elongation factor C/D (NELFCD) LDTP08594 7.57  LDD0467  Neudesin (NENF) LDTP13630 14.34  LDD0467  NHP2-like protein 1 (SNU13) LDTP04708 12.19  LDD0467  Nucleobindin-1 (NUCB1) LDTP05375 20.00  LDD0467  Nucleobindin-2 (NUCB2) LDTP05160 20.00  LDD0467  Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 5.28  LDD0468  Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 5.27  LDD0468  Phosducin-like protein 3 (PDCL3) LDTP11825 20.00  LDD0468  Plakophilin-3 (PKP3) LDTP14017 11.63  LDD0468  Polymerase delta-interacting protein 2 (POLDIP2) LDTP13906 20.00  LDD0468  Pre-mRNA-processing factor 40 homolog A (PRPF40A) LDTP01208 20.00  LDD0467  Prefoldin subunit 3 (VBP1) LDTP04935 5.74  LDD0468  Prelamin-A/C (LMNA) LDTP01932 17.40  LDD0467  Programmed cell death protein 4 (PDCD4) LDTP06881 12.46  LDD0467  Prohibitin-2 (PHB2) LDTP10924 8.25  LDD0467  Proteasome activator complex subunit 1 (PSME1) LDTP05484 20.00  LDD0482  Proteasome activator complex subunit 2 (PSME2) LDTP13519 7.00  LDD0467  Proteasome assembly chaperone 1 (PSMG1) LDTP01608 20.00  LDD0467  Protein FAM114A2 (FAM114A2) LDTP16080 20.00  LDD0467  Protein misato homolog 1 (MSTO1) LDTP11239 10.67  LDD0467  Protein NipSnap homolog 1 (NIPSNAP1) LDTP19912 5.04  LDD0467  Protein unc-13 homolog D (UNC13D) LDTP07888 5.39  LDD0468  Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 9.66  LDD0467  Replication protein A 70 kDa DNA-binding subunit (RPA1) LDTP03397 12.11  LDD0468  Reticulocalbin-1 (RCN1) LDTP06352 14.68  LDD0482  Reticulocalbin-2 (RCN2) LDTP06097 15.84  LDD0467  RNA binding motif protein, X-linked-like-1 (RBMXL1) LDTP18146 5.72  LDD0467  RNA-binding motif protein, X chromosome (RBMX) LDTP03850 5.22  LDD0467  RNA-binding protein 12B (RBM12B) LDTP17640 6.98  LDD0467  RNA-binding protein 14 (RBM14) LDTP10684 13.32  LDD0467  RNA-binding protein 4 (RBM4) LDTP11324 9.71  LDD0482  RNA-binding protein 4B (RBM4B) LDTP11046 20.00  LDD0467  RNA-binding protein EWS (EWSR1) LDTP05318 5.11  LDD0468  RNA-binding protein FUS (FUS) LDTP03775 7.21  LDD0467  RNA-binding protein FXR1 (FXR1) LDTP04395 5.08  LDD0468  RNA-binding protein FXR2 (FXR2) LDTP04396 12.84  LDD0467  Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 12.36  LDD0482  Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 5.08  LDD0467  Small ribosomal subunit protein mS27 (MRPS27) LDTP09793 5.25  LDD0467  Small ribosomal subunit protein mS39 (PTCD3) LDTP10285 5.17  LDD0467  Splicing factor 3A subunit 1 (SF3A1) LDTP06393 7.00  LDD0467  Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 20.00  LDD0467  Symplekin (SYMPK) LDTP09878 12.97  LDD0467  T-complex protein 1 subunit epsilon (CCT5) LDTP04201 6.35  LDD0467  TATA-binding protein-associated factor 2N (TAF15) LDTP09881 7.12  LDD0468  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 20.00  LDD0467  Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 20.00  LDD0482  TIP41-like protein (TIPRL) LDTP01285 5.08  LDD0468  Tubulin beta chain (TUBB) LDTP02205 9.76  LDD0467  Tubulin beta-2B chain (TUBB2B) LDTP11277 9.92  LDD0467  Tubulin beta-3 chain (TUBB3) LDTP05904 8.75  LDD0467  Tubulin beta-4A chain (TUBB4A) LDTP02037 8.45  LDD0468  Tubulin beta-4B chain (TUBB4B) LDTP05076 8.98  LDD0467  Tubulin beta-6 chain (TUBB6) LDTP11233 8.07  LDD0467  Tubulin beta-8 chain (TUBB8) LDTP06809 8.79  LDD0467  Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 16.88  LDD0482  Vacuolar protein sorting-associated protein 51 homolog (VPS51) LDTP13338 7.21  LDD0467  Vimentin (VIM) LDTP02297 15.04  LDD0467  YLP motif-containing protein 1 (YLPM1) LDTP04290 5.46  LDD0467  Zinc finger protein 503 (ZNF503) LDTP10295 20.00  LDD0467  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 112 Other

Competitor ID	Name	Concentration		Cell-system	Ref
LDCM0181	Compound 41	160 uM		Human normal cells (HEK-293T)	[1]
LDCM0182	Compound 18	160 uM		Human normal cells (HEK-293T)	[1]
LDCM0183	Compound 42	160 uM		Human normal cells (HEK-293T)	[1]

1	Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.