Details of the Target

General Information of Target

Target ID LDTP03846
Target Name Transgelin-2 (TAGLN2)
Gene Name TAGLN2
Gene ID 8407
Synonyms
KIAA0120; Transgelin-2; Epididymis tissue protein Li 7e; SM22-alpha homolog
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
Download
Sequence
MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
NRGASQAGMTGYGMPRQIL
Target Type
Literature-reported
Target Bioclass
Other
Family
Calponin family
TTD ID
T93147
Uniprot ID
P37802
DrugMap ID
TTP6BIJ
Ensemble ID
ENST00000320307.8
HGNC ID
HGNC:11554

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 56 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
P2
 Probe Info  		1.62  LDD0449  [2]
P3
 Probe Info  		2.82  LDD0450  [2]
P8
 Probe Info  		2.36  LDD0451  [2]
A-EBA
 Probe Info  		4.45  LDD0215  [3]
CY-1
 Probe Info  		100.00  LDD0243  [4]
CY4
 Probe Info  		100.00  LDD0244  [4]
TH211
 Probe Info  		Y103(6.44)  LDD0257  [5]
TH214
 Probe Info  		Y192(20.00)  LDD0258  [5]
TH216
 Probe Info  		Y8(6.03)  LDD0259  [5]
YN-1
 Probe Info  		100.00  LDD0444  [6]
BTD
 Probe Info  		C124(4.43)  LDD1699  [7]
AZ-9
 Probe Info  		E50(0.95); E169(1.02); E91(1.10); D41(1.45)  LDD2208  [8]
ONAyne
 Probe Info  		K40(0.00); K17(0.00); K156(0.00); K171(0.00)  LDD0273  [9]
OPA-S-S-alkyne
 Probe Info  		K156(1.43); K154(1.43); K40(2.67); K171(8.20)  LDD3494  [10]
Probe 1
 Probe Info  		Y8(17.14); Y192(150.98)  LDD3495  [11]
JZ128-DTB
 Probe Info  		C124(0.00); C38(0.00); C63(0.00)  LDD0462  [12]
THZ1-DTB
 Probe Info  		C63(1.10); C38(1.05); C124(0.96)  LDD0460  [12]
DA-P3
 Probe Info  		4.30  LDD0183  [13]
AHL-Pu-1
 Probe Info  		C38(3.84)  LDD0171  [14]
HHS-482
 Probe Info  		Y103(0.91); Y192(0.94); Y8(0.91)  LDD0285  [15]
HHS-475
 Probe Info  		Y8(0.81); Y192(0.88)  LDD0264  [16]
HHS-465
 Probe Info  		Y192(5.28); Y8(6.37)  LDD2237  [17]
DBIA
 Probe Info  		C124(1.05)  LDD0078  [18]
AMP probe
 Probe Info  		K153(0.00); K154(0.00)  LDD0200  [19]
ATP probe
 Probe Info  		K153(0.00); K154(0.00); K171(0.00); K79(0.00)  LDD0199  [19]
4-Iodoacetamidophenylacetylene
 Probe Info  		C63(0.00); C124(0.00); C38(0.00)  LDD0038  [20]
IA-alkyne
 Probe Info  		C38(0.00); C63(0.00); C124(0.00)  LDD0032  [21]
IPIAA_H
 Probe Info  		N.A.  LDD0030  [22]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [22]
Lodoacetamide azide
 Probe Info  		C63(0.00); C124(0.00); C38(0.00)  LDD0037  [20]
ATP probe
 Probe Info  		K78(0.00); K20(0.00); K88(0.00); K79(0.00)  LDD0035  [23]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [24]
NAIA_4
 Probe Info  		N.A.  LDD2226  [25]
TFBX
 Probe Info  		N.A.  LDD0027  [24]
WYneN
 Probe Info  		N.A.  LDD0021  [26]
WYneO
 Probe Info  		N.A.  LDD0022  [26]
1d-yne
 Probe Info  		N.A.  LDD0356  [27]
Compound 10
 Probe Info  		N.A.  LDD2216  [28]
ENE
 Probe Info  		N.A.  LDD0006  [26]
IPM
 Probe Info  		N.A.  LDD0005  [26]
NHS
 Probe Info  		K79(0.00); K171(0.00)  LDD0010  [26]
OSF
 Probe Info  		N.A.  LDD0029  [29]
PF-06672131
 Probe Info  		N.A.  LDD0152  [30]
SF
 Probe Info  		K17(0.00); K79(0.00); Y8(0.00); Y192(0.00)  LDD0028  [29]
STPyne
 Probe Info  		N.A.  LDD0009  [26]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [31]
1c-yne
 Probe Info  		K171(0.00); K153(0.00); K88(0.00); K20(0.00)  LDD0228  [27]
Acrolein
 Probe Info  		C38(0.00); C124(0.00)  LDD0217  [32]
Cinnamaldehyde
 Probe Info  		N.A.  LDD0220  [32]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [32]
Methacrolein
 Probe Info  		N.A.  LDD0218  [32]
MPP-AC
 Probe Info  		N.A.  LDD0428  [33]
NAIA_5
 Probe Info  		C63(0.00); C38(0.00); C124(0.00)  LDD2223  [25]
TER-AC
 Probe Info  		N.A.  LDD0426  [33]
TPP-AC
 Probe Info  		N.A.  LDD0427  [33]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe13
 Probe Info  		5.09  LDD0475  [34]
FFF probe3
 Probe Info  		5.29  LDD0464  [34]
STS-2
 Probe Info  		N.A.  LDD0139  [35]
STS-1
 Probe Info  		N.A.  LDD0069  [36]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C124(0.55)  LDD2142  [7]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C124(0.74)  LDD2112  [7]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C124(0.56)  LDD2095  [7]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C124(0.81)  LDD2130  [7]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C124(1.11)  LDD2117  [7]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C124(1.65)  LDD2152  [7]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C124(0.92)  LDD2103  [7]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C124(0.56)  LDD2132  [7]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C124(0.82)  LDD2131  [7]
 LDCM0026  4SU-RNA+native RNA DM93 C38(3.84)  LDD0171  [14]
 LDCM0214  AC1 HCT 116 C124(1.07)  LDD0531  [18]
 LDCM0215  AC10 HCT 116 C124(0.72)  LDD0532  [18]
 LDCM0216  AC100 HCT 116 C124(0.93)  LDD0533  [18]
 LDCM0217  AC101 HCT 116 C124(1.11)  LDD0534  [18]
 LDCM0218  AC102 HCT 116 C124(1.15)  LDD0535  [18]
 LDCM0219  AC103 HCT 116 C124(1.03)  LDD0536  [18]
 LDCM0220  AC104 HCT 116 C124(0.96)  LDD0537  [18]
 LDCM0221  AC105 HCT 116 C124(1.17)  LDD0538  [18]
 LDCM0222  AC106 HCT 116 C124(0.95)  LDD0539  [18]
 LDCM0223  AC107 HCT 116 C124(0.91)  LDD0540  [18]
 LDCM0224  AC108 HCT 116 C124(1.05)  LDD0541  [18]
 LDCM0225  AC109 HCT 116 C124(0.94)  LDD0542  [18]
 LDCM0226  AC11 HCT 116 C124(0.78)  LDD0543  [18]
 LDCM0227  AC110 HCT 116 C124(1.26)  LDD0544  [18]
 LDCM0228  AC111 HCT 116 C124(1.13)  LDD0545  [18]
 LDCM0229  AC112 HCT 116 C124(1.04)  LDD0546  [18]
 LDCM0230  AC113 HCT 116 C124(1.20)  LDD0547  [18]
 LDCM0231  AC114 HCT 116 C124(1.09)  LDD0548  [18]
 LDCM0232  AC115 HCT 116 C124(1.23)  LDD0549  [18]
 LDCM0233  AC116 HCT 116 C124(1.23)  LDD0550  [18]
 LDCM0234  AC117 HCT 116 C124(1.21)  LDD0551  [18]
 LDCM0235  AC118 HCT 116 C124(1.10)  LDD0552  [18]
 LDCM0236  AC119 HCT 116 C124(1.02)  LDD0553  [18]
 LDCM0237  AC12 HCT 116 C124(0.83)  LDD0554  [18]
 LDCM0238  AC120 HCT 116 C124(1.00)  LDD0555  [18]
 LDCM0239  AC121 HCT 116 C124(1.06)  LDD0556  [18]
 LDCM0240  AC122 HCT 116 C124(1.09)  LDD0557  [18]
 LDCM0241  AC123 HCT 116 C124(0.97)  LDD0558  [18]
 LDCM0242  AC124 HCT 116 C124(1.04)  LDD0559  [18]
 LDCM0243  AC125 HCT 116 C124(1.16)  LDD0560  [18]
 LDCM0244  AC126 HCT 116 C124(1.24)  LDD0561  [18]
 LDCM0245  AC127 HCT 116 C124(1.25)  LDD0562  [18]
 LDCM0246  AC128 HEK-293T C124(1.39)  LDD0844  [18]
 LDCM0247  AC129 HEK-293T C124(1.11)  LDD0845  [18]
 LDCM0249  AC130 HEK-293T C124(0.94)  LDD0847  [18]
 LDCM0250  AC131 HEK-293T C124(0.93)  LDD0848  [18]
 LDCM0251  AC132 HEK-293T C124(1.17)  LDD0849  [18]
 LDCM0252  AC133 HEK-293T C124(0.88)  LDD0850  [18]
 LDCM0253  AC134 HEK-293T C124(1.14)  LDD0851  [18]
 LDCM0254  AC135 HEK-293T C124(0.87)  LDD0852  [18]
 LDCM0255  AC136 HEK-293T C124(1.12)  LDD0853  [18]
 LDCM0256  AC137 HEK-293T C124(1.16)  LDD0854  [18]
 LDCM0257  AC138 HEK-293T C124(1.00)  LDD0855  [18]
 LDCM0258  AC139 HEK-293T C124(1.18)  LDD0856  [18]
 LDCM0259  AC14 HCT 116 C124(0.77)  LDD0576  [18]
 LDCM0260  AC140 HEK-293T C124(1.07)  LDD0858  [18]
 LDCM0261  AC141 HEK-293T C124(1.11)  LDD0859  [18]
 LDCM0262  AC142 HEK-293T C124(1.11)  LDD0860  [18]
 LDCM0263  AC143 HCT 116 C124(1.06)  LDD0580  [18]
 LDCM0264  AC144 HCT 116 C124(1.08)  LDD0581  [18]
 LDCM0265  AC145 HCT 116 C124(1.14)  LDD0582  [18]
 LDCM0266  AC146 HCT 116 C124(1.22)  LDD0583  [18]
 LDCM0267  AC147 HCT 116 C124(1.16)  LDD0584  [18]
 LDCM0268  AC148 HCT 116 C124(1.25)  LDD0585  [18]
 LDCM0269  AC149 HCT 116 C124(1.27)  LDD0586  [18]
 LDCM0270  AC15 HCT 116 C124(0.84)  LDD0587  [18]
 LDCM0271  AC150 HCT 116 C124(0.91)  LDD0588  [18]
 LDCM0272  AC151 HCT 116 C124(1.01)  LDD0589  [18]
 LDCM0273  AC152 HCT 116 C124(1.05)  LDD0590  [18]
 LDCM0274  AC153 HCT 116 C124(1.46)  LDD0591  [18]
 LDCM0621  AC154 HCT 116 C124(1.10)  LDD2158  [18]
 LDCM0622  AC155 HCT 116 C124(1.00)  LDD2159  [18]
 LDCM0623  AC156 HCT 116 C124(0.95)  LDD2160  [18]
 LDCM0624  AC157 HCT 116 C124(0.95)  LDD2161  [18]
 LDCM0276  AC17 HCT 116 C124(1.05)  LDD0593  [18]
 LDCM0277  AC18 HCT 116 C124(1.07)  LDD0594  [18]
 LDCM0278  AC19 HCT 116 C124(1.03)  LDD0595  [18]
 LDCM0279  AC2 HCT 116 C124(0.88)  LDD0596  [18]
 LDCM0280  AC20 HCT 116 C124(1.02)  LDD0597  [18]
 LDCM0281  AC21 HCT 116 C124(0.99)  LDD0598  [18]
 LDCM0282  AC22 HCT 116 C124(1.15)  LDD0599  [18]
 LDCM0283  AC23 HCT 116 C124(1.08)  LDD0600  [18]
 LDCM0284  AC24 HCT 116 C124(0.95)  LDD0601  [18]
 LDCM0285  AC25 HCT 116 C124(1.11)  LDD0602  [18]
 LDCM0286  AC26 HCT 116 C124(1.45)  LDD0603  [18]
 LDCM0287  AC27 HCT 116 C124(1.00)  LDD0604  [18]
 LDCM0288  AC28 HCT 116 C124(1.00)  LDD0605  [18]
 LDCM0289  AC29 HCT 116 C124(1.17)  LDD0606  [18]
 LDCM0290  AC3 HCT 116 C124(1.42)  LDD0607  [18]
 LDCM0291  AC30 HCT 116 C124(1.11)  LDD0608  [18]
 LDCM0292  AC31 HCT 116 C124(1.23)  LDD0609  [18]
 LDCM0293  AC32 HCT 116 C124(1.89)  LDD0610  [18]
 LDCM0294  AC33 HCT 116 C124(1.07)  LDD0611  [18]
 LDCM0295  AC34 HCT 116 C124(1.21)  LDD0612  [18]
 LDCM0296  AC35 HCT 116 C124(0.95)  LDD0613  [18]
 LDCM0297  AC36 HCT 116 C124(1.07)  LDD0614  [18]
 LDCM0298  AC37 HCT 116 C124(1.10)  LDD0615  [18]
 LDCM0299  AC38 HCT 116 C124(1.13)  LDD0616  [18]
 LDCM0300  AC39 HCT 116 C124(1.32)  LDD0617  [18]
 LDCM0301  AC4 HCT 116 C124(1.12)  LDD0618  [18]
 LDCM0302  AC40 HCT 116 C124(1.29)  LDD0619  [18]
 LDCM0303  AC41 HCT 116 C124(0.95)  LDD0620  [18]
 LDCM0304  AC42 HCT 116 C124(0.90)  LDD0621  [18]
 LDCM0305  AC43 HCT 116 C124(1.18)  LDD0622  [18]
 LDCM0306  AC44 HCT 116 C124(1.29)  LDD0623  [18]
 LDCM0307  AC45 HCT 116 C124(1.20)  LDD0624  [18]
 LDCM0308  AC46 HEK-293T C124(0.93); C38(0.89); C63(1.12)  LDD0906  [18]
 LDCM0309  AC47 HEK-293T C124(0.94); C38(0.89); C63(1.13)  LDD0907  [18]
 LDCM0310  AC48 HEK-293T C124(1.06); C38(0.75); C63(1.11)  LDD0908  [18]
 LDCM0311  AC49 HEK-293T C124(1.00); C38(0.83); C63(1.14)  LDD0909  [18]
 LDCM0312  AC5 HCT 116 C124(1.22)  LDD0629  [18]
 LDCM0313  AC50 HEK-293T C124(1.11); C38(0.70); C63(1.09)  LDD0911  [18]
 LDCM0314  AC51 HEK-293T C124(1.29); C38(0.83); C63(1.21)  LDD0912  [18]
 LDCM0315  AC52 HEK-293T C124(1.20); C38(0.86); C63(1.30)  LDD0913  [18]
 LDCM0316  AC53 HEK-293T C124(1.07); C38(0.87); C63(1.12)  LDD0914  [18]
 LDCM0317  AC54 HEK-293T C124(1.29); C38(0.85); C63(1.46)  LDD0915  [18]
 LDCM0318  AC55 HEK-293T C124(1.23); C38(0.82); C63(1.31)  LDD0916  [18]
 LDCM0319  AC56 HEK-293T C124(1.18); C38(0.78); C63(1.19)  LDD0917  [18]
 LDCM0320  AC57 HEK-293T C124(0.96); C38(0.99); C63(1.32)  LDD1559  [37]
 LDCM0321  AC58 HEK-293T C124(0.99); C38(1.11); C63(1.62)  LDD1560  [37]
 LDCM0322  AC59 HEK-293T C124(1.07); C38(1.31); C63(1.48)  LDD1561  [37]
 LDCM0323  AC6 HCT 116 C124(0.67)  LDD0640  [18]
 LDCM0324  AC60 HEK-293T C124(0.99); C38(1.22); C63(1.40)  LDD1563  [37]
 LDCM0325  AC61 HEK-293T C124(1.02); C38(1.23); C63(1.25)  LDD1564  [37]
 LDCM0326  AC62 HEK-293T C124(0.98); C38(1.16); C63(1.37)  LDD1565  [37]
 LDCM0327  AC63 HEK-293T C124(1.06); C38(1.22); C63(1.18)  LDD1566  [37]
 LDCM0328  AC64 HEK-293T C124(1.06); C38(1.23); C63(1.30)  LDD1567  [37]
 LDCM0332  AC68 PaTu 8988t C124(1.05); C63(1.16); C38(0.93)  LDD1211  [18]
 LDCM0333  AC69 PaTu 8988t C124(1.30); C63(1.19); C38(1.07)  LDD1212  [18]
 LDCM0334  AC7 HCT 116 C124(0.73)  LDD0651  [18]
 LDCM0335  AC70 PaTu 8988t C124(1.20); C63(1.13); C38(1.14)  LDD1214  [18]
 LDCM0336  AC71 PaTu 8988t C124(1.18); C63(0.95); C38(0.98)  LDD1215  [18]
 LDCM0337  AC72 PaTu 8988t C124(1.05); C63(0.93); C38(0.89)  LDD1216  [18]
 LDCM0338  AC73 PaTu 8988t C124(0.95); C63(1.24); C38(1.29)  LDD1217  [18]
 LDCM0339  AC74 PaTu 8988t C124(1.18); C63(1.05); C38(1.30)  LDD1218  [18]
 LDCM0340  AC75 PaTu 8988t C124(1.32); C63(0.98); C38(1.07)  LDD1219  [18]
 LDCM0341  AC76 PaTu 8988t C124(1.17); C63(0.86); C38(0.82)  LDD1220  [18]
 LDCM0342  AC77 PaTu 8988t C124(1.05); C63(0.95); C38(0.85)  LDD1221  [18]
 LDCM0343  AC78 PaTu 8988t C124(1.05); C63(1.01); C38(1.21)  LDD1222  [18]
 LDCM0344  AC79 PaTu 8988t C124(1.15); C63(1.09); C38(1.18)  LDD1223  [18]
 LDCM0345  AC8 HCT 116 C124(0.85)  LDD0662  [18]
 LDCM0346  AC80 PaTu 8988t C124(1.03); C63(1.03); C38(1.02)  LDD1225  [18]
 LDCM0347  AC81 PaTu 8988t C124(1.14); C63(1.07); C38(1.09)  LDD1226  [18]
 LDCM0348  AC82 PaTu 8988t C124(1.09); C63(1.16); C38(1.29)  LDD1227  [18]
 LDCM0349  AC83 HCT 116 C124(1.45)  LDD0666  [18]
 LDCM0350  AC84 HCT 116 C124(1.39)  LDD0667  [18]
 LDCM0351  AC85 HCT 116 C124(1.21)  LDD0668  [18]
 LDCM0352  AC86 HCT 116 C124(1.15)  LDD0669  [18]
 LDCM0353  AC87 HCT 116 C124(1.01)  LDD0670  [18]
 LDCM0354  AC88 HCT 116 C124(0.96)  LDD0671  [18]
 LDCM0355  AC89 HCT 116 C124(0.97)  LDD0672  [18]
 LDCM0357  AC90 HCT 116 C124(1.31)  LDD0674  [18]
 LDCM0358  AC91 HCT 116 C124(1.10)  LDD0675  [18]
 LDCM0359  AC92 HCT 116 C124(1.33)  LDD0676  [18]
 LDCM0360  AC93 HCT 116 C124(1.23)  LDD0677  [18]
 LDCM0361  AC94 HCT 116 C124(1.11)  LDD0678  [18]
 LDCM0362  AC95 HCT 116 C124(1.06)  LDD0679  [18]
 LDCM0363  AC96 HCT 116 C124(1.17)  LDD0680  [18]
 LDCM0364  AC97 HCT 116 C124(1.39)  LDD0681  [18]
 LDCM0365  AC98 HCT 116 C124(1.17)  LDD0682  [18]
 LDCM0366  AC99 HCT 116 C124(1.17)  LDD0683  [18]
 LDCM0545  Acetamide MDA-MB-231 C124(0.43)  LDD2138  [7]
 LDCM0520  AKOS000195272 MDA-MB-231 C124(0.82)  LDD2113  [7]
 LDCM0248  AKOS034007472 HCT 116 C124(0.68)  LDD0565  [18]
 LDCM0356  AKOS034007680 HCT 116 C124(0.74)  LDD0673  [18]
 LDCM0275  AKOS034007705 HCT 116 C124(0.85)  LDD0592  [18]
 LDCM0156  Aniline NCI-H1299 13.03  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C124(1.05)  LDD0078  [18]
 LDCM0498  BS-3668 MDA-MB-231 C124(0.28)  LDD2091  [7]
 LDCM0630  CCW28-3 231MFP C63(1.58)  LDD2214  [38]
 LDCM0108  Chloroacetamide HeLa C124(0.00); C38(0.00)  LDD0222  [32]
 LDCM0632  CL-Sc Hep-G2 C124(1.82)  LDD2227  [25]
 LDCM0367  CL1 HCT 116 C124(0.78)  LDD0684  [18]
 LDCM0368  CL10 HCT 116 C124(0.93)  LDD0685  [18]
 LDCM0369  CL100 HCT 116 C124(1.26)  LDD0686  [18]
 LDCM0370  CL101 HCT 116 C124(0.62)  LDD0687  [18]
 LDCM0371  CL102 HCT 116 C124(0.53)  LDD0688  [18]
 LDCM0372  CL103 HCT 116 C124(0.72)  LDD0689  [18]
 LDCM0373  CL104 HCT 116 C124(0.97)  LDD0690  [18]
 LDCM0374  CL105 HCT 116 C124(1.18)  LDD0691  [18]
 LDCM0375  CL106 HCT 116 C124(1.28)  LDD0692  [18]
 LDCM0376  CL107 HCT 116 C124(1.31)  LDD0693  [18]
 LDCM0377  CL108 HCT 116 C124(1.41)  LDD0694  [18]
 LDCM0378  CL109 HCT 116 C124(1.25)  LDD0695  [18]
 LDCM0379  CL11 HCT 116 C124(0.89)  LDD0696  [18]
 LDCM0380  CL110 HCT 116 C124(1.20)  LDD0697  [18]
 LDCM0381  CL111 HCT 116 C124(1.22)  LDD0698  [18]
 LDCM0382  CL112 HCT 116 C124(1.15)  LDD0699  [18]
 LDCM0383  CL113 HCT 116 C124(1.35)  LDD0700  [18]
 LDCM0384  CL114 HCT 116 C124(1.14)  LDD0701  [18]
 LDCM0385  CL115 HCT 116 C124(1.15)  LDD0702  [18]
 LDCM0386  CL116 HCT 116 C124(1.19)  LDD0703  [18]
 LDCM0387  CL117 HCT 116 C124(0.64)  LDD0704  [18]
 LDCM0388  CL118 HCT 116 C124(1.07)  LDD0705  [18]
 LDCM0389  CL119 HCT 116 C124(1.46)  LDD0706  [18]
 LDCM0390  CL12 HCT 116 C124(0.84)  LDD0707  [18]
 LDCM0391  CL120 HCT 116 C124(1.14)  LDD0708  [18]
 LDCM0392  CL121 HEK-293T C124(0.91); C38(0.85); C63(1.34)  LDD0990  [18]
 LDCM0393  CL122 HEK-293T C124(1.18); C38(0.93); C63(1.21)  LDD0991  [18]
 LDCM0394  CL123 HEK-293T C124(1.01); C38(0.79); C63(1.09)  LDD0992  [18]
 LDCM0395  CL124 HEK-293T C124(1.26); C38(0.89); C63(1.16)  LDD0993  [18]
 LDCM0396  CL125 HEK-293T C124(0.98); C38(1.29); C63(1.78)  LDD1600  [37]
 LDCM0397  CL126 HEK-293T C124(0.98); C38(1.44); C63(1.48)  LDD1601  [37]
 LDCM0398  CL127 HEK-293T C124(1.03); C38(1.08); C63(1.51)  LDD1602  [37]
 LDCM0399  CL128 HEK-293T C124(1.02); C38(1.37); C63(1.47)  LDD1603  [37]
 LDCM0400  CL13 HCT 116 C124(0.98)  LDD0717  [18]
 LDCM0401  CL14 HCT 116 C124(0.78)  LDD0718  [18]
 LDCM0402  CL15 HCT 116 C124(0.73)  LDD0719  [18]
 LDCM0403  CL16 HCT 116 C124(1.15)  LDD0720  [18]
 LDCM0404  CL17 HCT 116 C124(0.77)  LDD0721  [18]
 LDCM0405  CL18 HCT 116 C124(1.11)  LDD0722  [18]
 LDCM0406  CL19 HCT 116 C124(0.90)  LDD0723  [18]
 LDCM0407  CL2 HCT 116 C124(0.86)  LDD0724  [18]
 LDCM0408  CL20 HCT 116 C124(1.06)  LDD0725  [18]
 LDCM0409  CL21 HCT 116 C124(0.87)  LDD0726  [18]
 LDCM0410  CL22 HCT 116 C124(1.05)  LDD0727  [18]
 LDCM0411  CL23 HCT 116 C124(1.07)  LDD0728  [18]
 LDCM0412  CL24 HCT 116 C124(1.26)  LDD0729  [18]
 LDCM0413  CL25 HCT 116 C124(1.31)  LDD0730  [18]
 LDCM0414  CL26 HCT 116 C124(1.11)  LDD0731  [18]
 LDCM0415  CL27 HCT 116 C124(1.12)  LDD0732  [18]
 LDCM0416  CL28 HCT 116 C124(1.29)  LDD0733  [18]
 LDCM0417  CL29 HCT 116 C124(1.29)  LDD0734  [18]
 LDCM0418  CL3 HCT 116 C124(0.84)  LDD0735  [18]
 LDCM0419  CL30 HCT 116 C124(1.24)  LDD0736  [18]
 LDCM0420  CL31 HCT 116 C124(0.90)  LDD0737  [18]
 LDCM0421  CL32 HCT 116 C124(1.05)  LDD0738  [18]
 LDCM0422  CL33 HCT 116 C124(1.02)  LDD0739  [18]
 LDCM0423  CL34 HCT 116 C124(1.00)  LDD0740  [18]
 LDCM0424  CL35 HCT 116 C124(1.12)  LDD0741  [18]
 LDCM0425  CL36 HCT 116 C124(1.04)  LDD0742  [18]
 LDCM0426  CL37 HCT 116 C124(1.06)  LDD0743  [18]
 LDCM0428  CL39 HCT 116 C124(1.03)  LDD0745  [18]
 LDCM0429  CL4 HCT 116 C124(0.75)  LDD0746  [18]
 LDCM0430  CL40 HCT 116 C124(0.95)  LDD0747  [18]
 LDCM0431  CL41 HCT 116 C124(1.02)  LDD0748  [18]
 LDCM0432  CL42 HCT 116 C124(0.97)  LDD0749  [18]
 LDCM0433  CL43 HCT 116 C124(1.04)  LDD0750  [18]
 LDCM0434  CL44 HCT 116 C124(1.10)  LDD0751  [18]
 LDCM0435  CL45 HCT 116 C124(1.12)  LDD0752  [18]
 LDCM0436  CL46 HCT 116 C124(0.85)  LDD0753  [18]
 LDCM0437  CL47 HCT 116 C124(0.85)  LDD0754  [18]
 LDCM0438  CL48 HCT 116 C124(0.89)  LDD0755  [18]
 LDCM0439  CL49 HCT 116 C124(0.86)  LDD0756  [18]
 LDCM0440  CL5 HCT 116 C124(0.87)  LDD0757  [18]
 LDCM0441  CL50 HCT 116 C124(1.02)  LDD0758  [18]
 LDCM0442  CL51 HCT 116 C124(0.95)  LDD0759  [18]
 LDCM0443  CL52 HCT 116 C124(0.94)  LDD0760  [18]
 LDCM0444  CL53 HCT 116 C124(0.82)  LDD0761  [18]
 LDCM0445  CL54 HCT 116 C124(0.83)  LDD0762  [18]
 LDCM0446  CL55 HCT 116 C124(0.81)  LDD0763  [18]
 LDCM0447  CL56 HCT 116 C124(0.92)  LDD0764  [18]
 LDCM0448  CL57 HCT 116 C124(0.97)  LDD0765  [18]
 LDCM0449  CL58 HCT 116 C124(0.87)  LDD0766  [18]
 LDCM0450  CL59 HCT 116 C124(0.95)  LDD0767  [18]
 LDCM0451  CL6 HCT 116 C124(0.89)  LDD0768  [18]
 LDCM0452  CL60 HCT 116 C124(0.92)  LDD0769  [18]
 LDCM0453  CL61 HCT 116 C124(1.31)  LDD0770  [18]
 LDCM0454  CL62 HCT 116 C124(1.36)  LDD0771  [18]
 LDCM0455  CL63 HCT 116 C124(1.23)  LDD0772  [18]
 LDCM0456  CL64 HCT 116 C124(1.34)  LDD0773  [18]
 LDCM0457  CL65 HCT 116 C124(1.11)  LDD0774  [18]
 LDCM0458  CL66 HCT 116 C124(1.36)  LDD0775  [18]
 LDCM0459  CL67 HCT 116 C124(1.19)  LDD0776  [18]
 LDCM0460  CL68 HCT 116 C124(1.12)  LDD0777  [18]
 LDCM0461  CL69 HCT 116 C124(1.26)  LDD0778  [18]
 LDCM0462  CL7 HCT 116 C124(0.93)  LDD0779  [18]
 LDCM0463  CL70 HCT 116 C124(0.99)  LDD0780  [18]
 LDCM0464  CL71 HCT 116 C124(1.12)  LDD0781  [18]
 LDCM0465  CL72 HCT 116 C124(1.09)  LDD0782  [18]
 LDCM0466  CL73 HCT 116 C124(1.16)  LDD0783  [18]
 LDCM0467  CL74 HCT 116 C124(1.00)  LDD0784  [18]
 LDCM0469  CL76 HCT 116 C124(1.03)  LDD0786  [18]
 LDCM0470  CL77 HCT 116 C124(1.14)  LDD0787  [18]
 LDCM0471  CL78 HCT 116 C124(1.74)  LDD0788  [18]
 LDCM0472  CL79 HCT 116 C124(1.37)  LDD0789  [18]
 LDCM0473  CL8 HCT 116 C124(0.82)  LDD0790  [18]
 LDCM0474  CL80 HCT 116 C124(1.11)  LDD0791  [18]
 LDCM0475  CL81 HCT 116 C124(1.27)  LDD0792  [18]
 LDCM0476  CL82 HCT 116 C124(1.32)  LDD0793  [18]
 LDCM0477  CL83 HCT 116 C124(1.30)  LDD0794  [18]
 LDCM0478  CL84 HCT 116 C124(1.86)  LDD0795  [18]
 LDCM0479  CL85 HCT 116 C124(1.35)  LDD0796  [18]
 LDCM0480  CL86 HCT 116 C124(1.25)  LDD0797  [18]
 LDCM0481  CL87 HCT 116 C124(1.39)  LDD0798  [18]
 LDCM0482  CL88 HCT 116 C124(1.42)  LDD0799  [18]
 LDCM0483  CL89 HCT 116 C124(1.64)  LDD0800  [18]
 LDCM0484  CL9 HCT 116 C124(0.98)  LDD0801  [18]
 LDCM0485  CL90 HCT 116 C124(1.12)  LDD0802  [18]
 LDCM0486  CL91 HCT 116 C124(1.02)  LDD0803  [18]
 LDCM0487  CL92 HCT 116 C124(0.79)  LDD0804  [18]
 LDCM0488  CL93 HCT 116 C124(1.13)  LDD0805  [18]
 LDCM0489  CL94 HCT 116 C124(1.09)  LDD0806  [18]
 LDCM0490  CL95 HCT 116 C124(0.87)  LDD0807  [18]
 LDCM0491  CL96 HCT 116 C124(1.17)  LDD0808  [18]
 LDCM0492  CL97 HCT 116 C124(1.38)  LDD0809  [18]
 LDCM0493  CL98 HCT 116 C124(1.36)  LDD0810  [18]
 LDCM0494  CL99 HCT 116 C124(0.99)  LDD0811  [18]
 LDCM0634  CY-0357 Hep-G2 C124(0.94)  LDD2228  [25]
 LDCM0495  E2913 HEK-293T C124(1.05); C38(0.94); C63(0.90)  LDD1698  [37]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C124(1.01)  LDD1702  [7]
 LDCM0031  Epigallocatechin gallate HEK-293T 4.30  LDD0183  [13]
 LDCM0625  F8 Ramos C124(0.88); C63(0.65)  LDD2187  [39]
 LDCM0572  Fragment10 Ramos C124(0.79); C63(0.47)  LDD2189  [39]
 LDCM0573  Fragment11 Ramos C124(0.00)  LDD2190  [39]
 LDCM0574  Fragment12 Ramos C124(0.73); C63(0.40)  LDD2191  [39]
 LDCM0575  Fragment13 Ramos C124(0.92); C63(0.67)  LDD2192  [39]
 LDCM0576  Fragment14 Ramos C124(0.79); C63(1.16)  LDD2193  [39]
 LDCM0579  Fragment20 Ramos C124(0.56); C63(0.37)  LDD2194  [39]
 LDCM0580  Fragment21 Ramos C124(0.99); C63(0.79)  LDD2195  [39]
 LDCM0582  Fragment23 Ramos C124(0.61); C63(0.69)  LDD2196  [39]
 LDCM0578  Fragment27 Ramos C124(1.02); C63(0.83)  LDD2197  [39]
 LDCM0586  Fragment28 Ramos C124(0.74); C63(0.66)  LDD2198  [39]
 LDCM0588  Fragment30 Ramos C124(1.13); C63(0.68)  LDD2199  [39]
 LDCM0589  Fragment31 Ramos C124(1.08); C63(0.84)  LDD2200  [39]
 LDCM0590  Fragment32 Ramos C124(0.62); C63(0.45)  LDD2201  [39]
 LDCM0468  Fragment33 HCT 116 C124(1.32)  LDD0785  [18]
 LDCM0596  Fragment38 Ramos C124(0.99); C63(0.53)  LDD2203  [39]
 LDCM0566  Fragment4 Ramos C124(0.64); C63(0.48)  LDD2184  [39]
 LDCM0427  Fragment51 HCT 116 C124(0.98)  LDD0744  [18]
 LDCM0610  Fragment52 Ramos C124(1.03); C63(0.59)  LDD2204  [39]
 LDCM0614  Fragment56 Ramos C124(1.30); C63(0.88)  LDD2205  [39]
 LDCM0569  Fragment7 Ramos C124(0.66); C63(0.58)  LDD2186  [39]
 LDCM0571  Fragment9 Ramos C124(0.53); C63(0.49)  LDD2188  [39]
 LDCM0116  HHS-0101 DM93 Y8(0.81); Y192(0.88)  LDD0264  [16]
 LDCM0117  HHS-0201 DM93 Y8(0.74); Y192(0.84)  LDD0265  [16]
 LDCM0118  HHS-0301 DM93 Y8(0.75); Y192(0.81)  LDD0266  [16]
 LDCM0119  HHS-0401 DM93 Y192(0.80); Y8(0.80)  LDD0267  [16]
 LDCM0120  HHS-0701 DM93 Y8(0.85); Y192(0.96)  LDD0268  [16]
 LDCM0107  IAA HeLa N.A.  LDD0221  [32]
 LDCM0123  JWB131 DM93 Y103(0.91); Y192(0.94); Y8(0.91)  LDD0285  [15]
 LDCM0124  JWB142 DM93 Y103(0.61); Y192(0.79); Y8(0.78)  LDD0286  [15]
 LDCM0125  JWB146 DM93 Y103(1.10); Y192(0.90); Y8(1.03)  LDD0287  [15]
 LDCM0126  JWB150 DM93 Y103(6.46); Y192(4.18); Y8(3.23)  LDD0288  [15]
 LDCM0127  JWB152 DM93 Y103(4.77); Y192(2.56); Y8(2.09)  LDD0289  [15]
 LDCM0128  JWB198 DM93 Y103(0.21); Y192(1.61); Y8(1.36)  LDD0290  [15]
 LDCM0129  JWB202 DM93 Y103(0.76); Y192(0.75); Y8(0.66)  LDD0291  [15]
 LDCM0130  JWB211 DM93 Y103(0.56); Y192(1.06); Y8(1.02)  LDD0292  [15]
 LDCM0179  JZ128 PC-3 C124(0.00); C38(0.00); C63(0.00)  LDD0462  [12]
 LDCM0022  KB02 HCT 116 C124(1.07)  LDD0080  [18]
 LDCM0023  KB03 HCT 116 C124(1.10)  LDD0081  [18]
 LDCM0024  KB05 HCT 116 C124(1.42)  LDD0082  [18]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C124(1.00)  LDD2102  [7]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C124(0.45)  LDD2121  [7]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C124(0.46)  LDD2089  [7]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C124(1.50)  LDD2090  [7]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C124(1.06)  LDD2092  [7]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C124(2.49)  LDD2093  [7]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C124(2.10)  LDD2094  [7]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C124(0.69)  LDD2097  [7]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C124(0.47)  LDD2098  [7]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C124(1.14)  LDD2099  [7]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C124(0.48)  LDD2100  [7]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C124(1.10)  LDD2101  [7]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C124(0.84)  LDD2104  [7]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C124(1.54)  LDD2105  [7]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C124(0.97)  LDD2106  [7]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C124(1.04)  LDD2107  [7]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C124(0.27)  LDD2108  [7]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C124(1.06)  LDD2109  [7]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C124(3.17)  LDD2110  [7]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C124(1.26)  LDD2111  [7]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C124(1.00)  LDD2114  [7]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C124(0.73)  LDD2115  [7]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C124(0.17)  LDD2118  [7]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C124(4.17)  LDD2119  [7]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C124(0.99)  LDD2120  [7]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C124(0.06)  LDD2122  [7]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C124(1.03)  LDD2123  [7]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C124(0.05)  LDD2124  [7]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C124(1.24)  LDD2125  [7]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C124(0.06)  LDD2126  [7]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C124(1.24)  LDD2127  [7]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C124(1.52)  LDD2128  [7]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C124(1.53)  LDD2129  [7]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C124(0.86)  LDD2133  [7]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C124(0.69)  LDD2134  [7]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C124(1.42)  LDD2135  [7]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C124(1.12)  LDD2136  [7]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C124(1.21)  LDD2137  [7]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C124(1.26)  LDD1700  [7]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C124(0.96)  LDD2140  [7]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C124(0.30)  LDD2141  [7]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C124(1.08)  LDD2143  [7]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C124(5.00)  LDD2144  [7]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C124(1.30)  LDD2145  [7]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C124(1.30)  LDD2146  [7]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C124(3.28)  LDD2147  [7]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C124(0.82)  LDD2148  [7]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C124(0.05)  LDD2149  [7]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C124(0.39)  LDD2150  [7]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C124(0.07)  LDD2151  [7]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C124(1.34)  LDD2153  [7]
 LDCM0627  NUDT7-COV-1 HEK-293T C124(0.87); C124(0.70)  LDD2206  [40]
 LDCM0628  OTUB2-COV-1 HEK-293T C124(0.77); C124(0.71)  LDD2207  [40]
 LDCM0131  RA190 MM1.R C63(1.32); C38(1.28); C124(1.13)  LDD0304  [41]
 LDCM0021  THZ1 HeLa S3 C63(1.10); C38(1.05); C124(0.96)  LDD0460  [12]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Actin, cytoplasmic 1 (ACTB) Actin family P60709
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ganglioside-induced differentiation-associated protein 1 (GDAP1) GST superfamily Q8TB36
Survival motor neuron protein (SMN1; SMN2) SMN family Q16637

The Drug(s) Related To This Target

Approved
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Artenimol . DB11638

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem. 2022 Dec 16;23(24):e202200389. doi: 10.1002/cbic.202200389. Epub 2022 Nov 22.
3 2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print.
Mass spectrometry data entry: PXD037665
4 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
5 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
6 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD042888
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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24 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
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30 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
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31 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
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38 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
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40 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
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