General Information of Experiment

Probe Name THZ1-DTB  Probe Info 
Probe concentration 2 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
iTRAQ
Competitor Name THZ1  Competitor Info 
Competitor Concentration 5 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Cervix uteri
Disease Model Cervical cancer [ICD11: 2C77]
Model Name Human cervical adenocarcinoma cell lysate (HeLa S3)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 289 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP04379  Cyclin-dependent kinase 7 (CDK7) C312 8.0
 LDTP12852  Cyclin-dependent kinase 12 (CDK12) C1039 6.2
 LDTP06019  Cyclin-dependent kinase 13 (CDK13) C1017 3.8
 LDTP07546  Serine/threonine-protein kinase N3 (PKN3) C840 3.3
 LDTP05433  Protein kinase C theta type (PRKCQ) C661 2.8
 LDTP06608  Cytochrome P450 1B1 (CYP1B1) C92 1.7
 LDTP04319  Glycogen synthase kinase-3 beta (GSK3B) C14 1.5
 LDTP00491  Aurora kinase A (AURKA) C33 1.4
 LDTP04499  6-phosphogluconate dehydrogenase, decarboxylating (PGD) C171 1.3
 LDTP00747  Mitogen-activated protein kinase kinase kinase 7 (MAP3K7) C302 1.3
 LDTP03679  Dual specificity protein kinase TTK (TTK) C465 1.3
 LDTP02824  Ribosyldihydronicotinamide dehydrogenase [quinone] (NQO2) C223 1.2
 LDTP02733  Pyruvate kinase PKM (PKM) C49 1.2
 LDTP04074  Ubiquitin carboxyl-terminal hydrolase 5 (USP5) C335 1.2
 LDTP04471  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) C579 1.2
 LDTP05052  S-phase kinase-associated protein 1 (SKP1) C62 1.2
 LDTP05481  Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) C264 1.2
 LDTP04251  Elongation factor Tu, mitochondrial (TUFM) C293 1.2
 LDTP04243  Fatty acid synthase (FASN) C2468 1.2
 LDTP02225  Heat shock protein HSP 90-alpha (HSP90AA1) C481 1.2
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) C184 1.2
 LDTP03591  Carbamoyl-phosphate synthase [ammonia], mitochondrial (CPS1) C1337 1.2
 LDTP05503  Peroxiredoxin-1 (PRDX1) C173 1.1
 LDTP02038  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) C152 1.1
 LDTP02502  Thioredoxin (TXN) C73 1.1
 LDTP02672  Elongation factor 2 (EEF2) C728 1.1
 LDTP03510  Peroxiredoxin-6 (PRDX6) C91 1.1
 LDTP02222  Bifunctional glutamate/proline--tRNA ligase (EPRS1) C1448 1.1
 LDTP03626  Peroxiredoxin-2 (PRDX2) C172 1.1
 LDTP04243  Fatty acid synthase (FASN) C212 1.1
 LDTP03591  Carbamoyl-phosphate synthase [ammonia], mitochondrial (CPS1) C1327 1.1
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) C369 1.1
 LDTP02452  Tubulin alpha-3C chain (TUBA3C) C347 1.1
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA) C178 1.1
 LDTP03541  Adenylosuccinate synthetase isozyme 2 (ADSS2) C182 1.1
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC) C3347 1.1
 LDTP04164  NADP-dependent malic enzyme (ME1) C468 1.1
 LDTP04243  Fatty acid synthase (FASN) C2202 1.1
 LDTP14092  Protein phosphatase methylesterase 1 (PPME1) C381 1.1
 LDTP03947  Isoleucine--tRNA ligase, cytoplasmic (IARS1) C400 1.1
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC) C223 1.1
 LDTP04963  26S proteasome regulatory subunit 8 (PSMC5) C112 1.1
 LDTP02159  Alpha-enolase (ENO1) C119 1.1
 LDTP02038  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) C156 1.1
 LDTP03908  Malate dehydrogenase, mitochondrial (MDH2) C212 1.1
 LDTP01766  L-lactate dehydrogenase A chain (LDHA) C163 1.1
 LDTP01787  Phosphoglycerate kinase 1 (PGK1) C99 1.1
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) C64 1.1
 LDTP02924  Probable ATP-dependent RNA helicase DDX5 (DDX5) C234 1.1
 LDTP05007  GTP-binding nuclear protein Ran (RAN) C120 1.1
 LDTP00418  Protein arginine N-methyltransferase 5 (PRMT5) C22 1.1
 LDTP03859  V-type proton ATPase catalytic subunit A (ATP6V1A) C240 1.1
 LDTP05009  Ras-related protein Rap-1A (RAP1A) C139 1.1
 LDTP03915  Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) C434 1.1
 LDTP03680  DNA replication licensing factor MCM4 (MCM4) C212 1.1
 LDTP03145  Catechol O-methyltransferase (COMT) C145 1.1
 LDTP05623  Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) C229 1.1
 LDTP05991  Spliceosome RNA helicase DDX39B (DDX39B) C75 1.1
 LDTP04876  Actin, cytoplasmic 1 (ACTB) C217 1.1
 LDTP02672  Elongation factor 2 (EEF2) C693 1.1
 LDTP00866  Asparagine--tRNA ligase, cytoplasmic (NARS1) C202 1.1
 LDTP03365  Threonine--tRNA ligase 1, cytoplasmic (TARS1) C107 1.1
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) C213 1.1
 LDTP03487  Transketolase (TKT) C386 1.1
 LDTP02713  Macrophage migration inhibitory factor (MIF) C81 1.1
 LDTP02768  Ras-related C3 botulinum toxin substrate 2 (RAC2) C157 1.1
 LDTP03365  Threonine--tRNA ligase 1, cytoplasmic (TARS1) C630 1.1
 LDTP05481  Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) C55 1.1
 LDTP02261  ATP-dependent 6-phosphofructokinase, muscle type (PFKM) C550 1.1
 LDTP05075  Tubulin alpha-4A chain (TUBA4A) C54 1.1
 LDTP02733  Pyruvate kinase PKM (PKM) C152 1.1
 LDTP00285  Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) C562 1.1
 LDTP03891  Nicotinamide N-methyltransferase (NNMT) C170 1.1
 LDTP04851  Triosephosphate isomerase (TPI1) C127 1.1
 LDTP00407  Prostaglandin E synthase (PTGES) C137 1.1
 LDTP03522  Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) C148 1.1
 LDTP14198  Phosphoserine aminotransferase (PSAT1) C80 1.1
 LDTP01245  Enoyl-CoA delta isomerase 2 (ECI2) C282 1.1
 LDTP05258  Sorbitol dehydrogenase (SORD) C130 1.1
 LDTP03591  Carbamoyl-phosphate synthase [ammonia], mitochondrial (CPS1) C1126 1.1
 LDTP05434  Lactoylglutathione lyase (GLO1) C139 1.1
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) C315 1.1
 LDTP01807  Argininosuccinate synthase (ASS1) C132 1.1
 LDTP04665  Transitional endoplasmic reticulum ATPase (VCP) C572 1.1
 LDTP03398  DNA repair nuclease/redox regulator APEX1 (APEX1) C208 1.1
 LDTP04096  Vesicle-fusing ATPase (NSF) C599 1.1
 LDTP03915  Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) C269 1.1
 LDTP04243  Fatty acid synthase (FASN) C1992 1.1
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA) C339 1.1
 LDTP03166  Ubiquitin-like modifier-activating enzyme 1 (UBA1) C278 1.1
 LDTP02248  Rho-related GTP-binding protein RhoC (RHOC) C16 1.1
 LDTP02770  Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) C276 1.1
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) C347 1.1
 LDTP02225  Heat shock protein HSP 90-alpha (HSP90AA1) C529 1.1
 LDTP05007  GTP-binding nuclear protein Ran (RAN) C112 1.1
 LDTP03872  Flap endonuclease 1 (FEN1) C235 1.1
 LDTP03366  Valine--tRNA ligase (VARS1) C112 1.1
 LDTP11070  Vitamin K epoxide reductase complex subunit 1 (VKORC1) C43 1.1
 LDTP02672  Elongation factor 2 (EEF2) C651 1.1
 LDTP03222  Tryptophan--tRNA ligase, cytoplasmic (WARS1) C309 1.1
 LDTP14198  Phosphoserine aminotransferase (PSAT1) C98 1.1
 LDTP05192  ADP-ribosylation factor 1 (ARF1) C159 1.1
 LDTP04999  Actin, aortic smooth muscle (ACTA2) C219 1.1
 LDTP13409  Anaphase-promoting complex subunit 7 (ANAPC7) C417 1.1
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) C281 1.1
 LDTP02733  Pyruvate kinase PKM (PKM) C326 1.1
 LDTP15993  Aminopeptidase B (RNPEP) C181 1.1
 LDTP05314  ATP-dependent 6-phosphofructokinase, platelet type (PFKP) C641 1.1
 LDTP02159  Alpha-enolase (ENO1) C339 1.1
 LDTP02225  Heat shock protein HSP 90-alpha (HSP90AA1) C597 1.1
 LDTP02220  Adenine phosphoribosyltransferase (APRT) C83 1.1
 LDTP03947  Isoleucine--tRNA ligase, cytoplasmic (IARS1) C87 1.1
 LDTP01782  Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) C106 1.1
 LDTP02672  Elongation factor 2 (EEF2) C591 1.1
 LDTP01787  Phosphoglycerate kinase 1 (PGK1) C367 1.1
 LDTP03689  Serine hydroxymethyltransferase, mitochondrial (SHMT2) C119 1.1
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) C411 1.1
 LDTP13618  ATP-dependent RNA helicase DDX19B (DDX19B) C225 1.1
 LDTP03730  Sepiapterin reductase (SPR) C159 1.1
 LDTP04243  Fatty acid synthase (FASN) C1127 1.1
 LDTP02198  Cathepsin D (CTSD) C329 1.1
 LDTP03577  S-adenosylmethionine synthase isoform type-2 (MAT2A) C149 1.1
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC) C232 1.1
 LDTP04392  Sodium/potassium-transporting ATPase subunit alpha-2 (ATP1A2) C372 1.1
 LDTP03591  Carbamoyl-phosphate synthase [ammonia], mitochondrial (CPS1) C600 1.1
 LDTP04886  Cell division control protein 42 homolog (CDC42) C157 1.1
 LDTP03159  Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) C288 1.1
 LDTP04531  Hexokinase-2 (HK2) C628 1.1
 LDTP09110  NAD(P)H-hydrate epimerase (NAXE) C127 1.1
 LDTP03365  Threonine--tRNA ligase 1, cytoplasmic (TARS1) C343 1.1
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) C234 1.1
 LDTP02672  Elongation factor 2 (EEF2) C812 1.1
 LDTP03591  Carbamoyl-phosphate synthase [ammonia], mitochondrial (CPS1) C761 1.1
 LDTP01508  Aflatoxin B1 aldehyde reductase member 3 (AKR7A3) C186 1.1
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC) C2093 1.1
 LDTP02592  Ribose-phosphate pyrophosphokinase 2 (PRPS2) C91 1.1
 LDTP02522  60 kDa heat shock protein, mitochondrial (HSPD1) C447 1.1
 LDTP00218  NADH dehydrogenase iron-sulfur protein 8, mitochondrial (NDUFS8) C121 1.1
 LDTP02452  Tubulin alpha-3C chain (TUBA3C) C25 1.1
 LDTP01787  Phosphoglycerate kinase 1 (PGK1) C50 1.1
 LDTP02452  Tubulin alpha-3C chain (TUBA3C) C376 1.1
 LDTP04561  ATP-citrate synthase (ACLY) C633 1.1
 LDTP02721  Farnesyl pyrophosphate synthase (FDPS) C333 1.1
 LDTP13750  Proliferation-associated protein 2G4 (PA2G4) C49 1.1
 LDTP02963  Phosphoglycerate mutase 1 (PGAM1) C55 1.1
 LDTP04987  26S proteasome regulatory subunit 10B (PSMC6) C193 1.1
 LDTP03859  V-type proton ATPase catalytic subunit A (ATP6V1A) C532 1.1
 LDTP02521  S-formylglutathione hydrolase (ESD) C176 1.1
 LDTP02733  Pyruvate kinase PKM (PKM) C358 1.1
 LDTP04601  Arginine--tRNA ligase, cytoplasmic (RARS1) C369 1.1
 LDTP03223  Small ribosomal subunit protein uS3 (RPS3) C97 1.1
 LDTP01787  Phosphoglycerate kinase 1 (PGK1) C380 1.1
 LDTP03166  Ubiquitin-like modifier-activating enzyme 1 (UBA1) C1040 1.1
 LDTP02733  Pyruvate kinase PKM (PKM) C474 1.1
 LDTP03572  Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) C89 1.1
 LDTP03847  Transaldolase (TALDO1) C250 1.1
 LDTP09110  NAD(P)H-hydrate epimerase (NAXE) C115 1.1
 LDTP04243  Fatty acid synthase (FASN) C1141 1.1
 LDTP02521  S-formylglutathione hydrolase (ESD) C181 1.1
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA) C290 1.1
 LDTP02672  Elongation factor 2 (EEF2) C369 1.1
 LDTP03522  Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) C390 1.1
 LDTP11074  Tubulin alpha-1C chain (TUBA1C) C376 1.1
 LDTP03891  Nicotinamide N-methyltransferase (NNMT) C159 1.0
 LDTP04253  Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) C478 1.0
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) C295 1.0
 LDTP06192  Neutral alpha-glucosidase AB (GANAB) C502 1.0
 LDTP01766  L-lactate dehydrogenase A chain (LDHA) C293 1.0
 LDTP05369  Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) C376 1.0
 LDTP02452  Tubulin alpha-3C chain (TUBA3C) C295 1.0
 LDTP03366  Valine--tRNA ligase (VARS1) C917 1.0
 LDTP05028  Peptidyl-prolyl cis-trans isomerase A (PPIA) C62 1.0
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) C315 1.0
 LDTP00558  Phospholipid scramblase 1 (PLSCR1) C148 1.0
 LDTP02541  Heat shock cognate 71 kDa protein (HSPA8) C17 1.0
 LDTP14092  Protein phosphatase methylesterase 1 (PPME1) C347 1.0
 LDTP02222  Bifunctional glutamate/proline--tRNA ligase (EPRS1) C1480 1.0
 LDTP04243  Fatty acid synthase (FASN) C1448 1.0
 LDTP02963  Phosphoglycerate mutase 1 (PGAM1) C153 1.0
 LDTP02162  Glucose-6-phosphate isomerase (GPI) C404 1.0
 LDTP02796  Nucleoside diphosphate kinase A (NME1) C109 1.0
 LDTP06006  Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) C80 1.0
 LDTP06192  Neutral alpha-glucosidase AB (GANAB) C423 1.0
 LDTP03166  Ubiquitin-like modifier-activating enzyme 1 (UBA1) C234 1.0
 LDTP03644  Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) C262 1.0
 LDTP04262  Alanine--tRNA ligase, cytoplasmic (AARS1) C947 1.0
 LDTP06294  Lysine--tRNA ligase (KARS1) C427 1.0
 LDTP04243  Fatty acid synthase (FASN) C496 1.0
 LDTP02521  S-formylglutathione hydrolase (ESD) C243 1.0
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) C370 1.0
 LDTP01220  Mitochondrial-processing peptidase subunit beta (PMPCB) C419 1.0
 LDTP04730  Methionine--tRNA ligase, cytoplasmic (MARS1) C12 1.0
 LDTP16025  Ketosamine-3-kinase (FN3KRP) C24 1.0
 LDTP02770  Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) C237 1.0
 LDTP02159  Alpha-enolase (ENO1) C337 1.0
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) C363 1.0
 LDTP04243  Fatty acid synthase (FASN) C1459 1.0
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) C106 1.0
 LDTP09110  NAD(P)H-hydrate epimerase (NAXE) C91 1.0
 LDTP02179  L-lactate dehydrogenase B chain (LDHB) C294 1.0
 LDTP09126  Probable aminopeptidase NPEPL1 (NPEPL1) C67 1.0
 LDTP02796  Nucleoside diphosphate kinase A (NME1) C145 1.0
 LDTP04243  Fatty acid synthase (FASN) C2273 1.0
 LDTP02452  Tubulin alpha-3C chain (TUBA3C) C20 1.0
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) C200 1.0
 LDTP04618  Ubiquitin carboxyl-terminal hydrolase 14 (USP14) C415 1.0
 LDTP11690  RNA cytidine acetyltransferase (NAT10) C255 1.0
 LDTP04333  GMP synthase [glutamine-hydrolyzing] (GMPS) C456 1.0
 LDTP04442  Ubiquitin-conjugating enzyme E2 D1 (UBE2D1) C85 1.0
 LDTP03689  Serine hydroxymethyltransferase, mitochondrial (SHMT2) C80 1.0
 LDTP15371  Aldehyde dehydrogenase family 16 member A1 (ALDH16A1) C71 1.0
 LDTP03366  Valine--tRNA ligase (VARS1) C41 1.0
 LDTP04243  Fatty acid synthase (FASN) C1471 1.0
 LDTP03166  Ubiquitin-like modifier-activating enzyme 1 (UBA1) C1039 1.0
 LDTP05314  ATP-dependent 6-phosphofructokinase, platelet type (PFKP) C123 1.0
 LDTP02159  Alpha-enolase (ENO1) C119 1.0
 LDTP02159  Alpha-enolase (ENO1) C389 1.0
 LDTP03515  Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) C229 1.0
 LDTP05028  Peptidyl-prolyl cis-trans isomerase A (PPIA) C161 1.0
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA) C73 1.0
 LDTP03510  Peroxiredoxin-6 (PRDX6) C47 1.0
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) C233 1.0
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) C120 1.0
 LDTP03591  Carbamoyl-phosphate synthase [ammonia], mitochondrial (CPS1) C516 1.0
 LDTP04665  Transitional endoplasmic reticulum ATPase (VCP) C415 1.0
 LDTP02672  Elongation factor 2 (EEF2) C466 1.0
 LDTP05258  Sorbitol dehydrogenase (SORD) C120 1.0
 LDTP02264  Asparagine synthetase [glutamine-hydrolyzing] (ASNS) C158 1.0
 LDTP11070  Vitamin K epoxide reductase complex subunit 1 (VKORC1) C51 1.0
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC) C1432 1.0
 LDTP00527  Phosphoribosylformylglycinamidine synthase (PFAS) C1285 1.0
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) C65 1.0
 LDTP00866  Asparagine--tRNA ligase, cytoplasmic (NARS1) C438 1.0
 LDTP03730  Sepiapterin reductase (SPR) C10 1.0
 LDTP02924  Probable ATP-dependent RNA helicase DDX5 (DDX5) C221 1.0
 LDTP03156  Trifunctional purine biosynthetic protein adenosine-3 (GART) C646 1.0
 LDTP11059  ADP-ribose glycohydrolase MACROD1 (MACROD1) C246 1.0
 LDTP03680  DNA replication licensing factor MCM4 (MCM4) C572 1.0
 LDTP02038  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) C247 1.0
 LDTP06314  Protein disulfide-isomerase A6 (PDIA6) C297 1.0
 LDTP03487  Transketolase (TKT) C417 1.0
 LDTP00527  Phosphoribosylformylglycinamidine synthase (PFAS) C1287 1.0
 LDTP03908  Malate dehydrogenase, mitochondrial (MDH2) C89 1.0
 LDTP05588  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) C673 1.0
 LDTP05314  ATP-dependent 6-phosphofructokinase, platelet type (PFKP) C718 1.0
 LDTP01787  Phosphoglycerate kinase 1 (PGK1) C316 1.0
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) C713 1.0
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) C200 1.0
 LDTP02534  Endoplasmic reticulum chaperone BiP (HSPA5) C420 1.0
 LDTP04876  Actin, cytoplasmic 1 (ACTB) C257 1.0
 LDTP08135  E3 ubiquitin-protein ligase HUWE1 (HUWE1) C612 1.0
 LDTP09921  Regulator of nonsense transcripts 1 (UPF1) C657 1.0
 LDTP03891  Nicotinamide N-methyltransferase (NNMT) C165 1.0
 LDTP04886  Cell division control protein 42 homolog (CDC42) C105 1.0
 LDTP03907  Malate dehydrogenase, cytoplasmic (MDH1) C137 1.0
 LDTP12297  Thioredoxin reductase 2, mitochondrial (TXNRD2) C91 1.0
 LDTP00527  Phosphoribosylformylglycinamidine synthase (PFAS) C697 1.0
 LDTP04876  Actin, cytoplasmic 1 (ACTB) C272 1.0
 LDTP01787  Phosphoglycerate kinase 1 (PGK1) C108 1.0
 LDTP03947  Isoleucine--tRNA ligase, cytoplasmic (IARS1) C357 1.0
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) C254 1.0
 LDTP15391  Probable phosphoglycerate mutase 4 (PGAM4) C55 1.0
 LDTP03908  Malate dehydrogenase, mitochondrial (MDH2) C93 1.0
 LDTP03166  Ubiquitin-like modifier-activating enzyme 1 (UBA1) C632 1.0
 LDTP04876  Actin, cytoplasmic 1 (ACTB) C285 1.0
 LDTP12297  Thioredoxin reductase 2, mitochondrial (TXNRD2) C86 1.0
 LDTP03159  Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) C295 1.0
 LDTP06314  Protein disulfide-isomerase A6 (PDIA6) C55 1.0
 LDTP03156  Trifunctional purine biosynthetic protein adenosine-3 (GART) C237 1.0
 LDTP11074  Tubulin alpha-1C chain (TUBA1C) C295 1.0
 LDTP03487  Transketolase (TKT) C413 1.0
 LDTP02522  60 kDa heat shock protein, mitochondrial (HSPD1) C442 1.0
 LDTP04618  Ubiquitin carboxyl-terminal hydrolase 14 (USP14) C114 1.0
 LDTP02672  Elongation factor 2 (EEF2) C751 1.0
 LDTP14198  Phosphoserine aminotransferase (PSAT1) C291 1.0
 LDTP12473  Sialic acid synthase (NANS) C180 1.0
 LDTP03947  Isoleucine--tRNA ligase, cytoplasmic (IARS1) C433 1.0
 LDTP02587  Alcohol dehydrogenase class-3 (ADH5) C97 1.0
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) C275 1.0
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) C421 1.0
 LDTP02587  Alcohol dehydrogenase class-3 (ADH5) C100 1.0
 LDTP06314  Protein disulfide-isomerase A6 (PDIA6) C58 1.0
 LDTP01766  L-lactate dehydrogenase A chain (LDHA) C185 0.9
 LDTP02922  CTP synthase 1 (CTPS1) C216 0.9
 LDTP09865  Histone deacetylase 2 (HDAC2) C111 0.9
 LDTP04243  Fatty acid synthase (FASN) C1881 0.9
 LDTP03611  3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) C199 0.9
 LDTP10954  3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) C214 0.8
 LDTP03541  Adenylosuccinate synthetase isozyme 2 (ADSS2) C280 0.7
Transporter and channel
Click to Show/Hide to Show 60 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP03385  14-3-3 protein theta (YWHAQ) C237 1.4
 LDTP01574  Importin-7 (IPO7) C736 1.2
 LDTP05252  Clathrin heavy chain 1 (CLTC) C1205 1.2
 LDTP00501  Exportin-1 (XPO1) C164 1.2
 LDTP04391  T-complex protein 1 subunit delta (CCT4) C252 1.2
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) C129 1.1
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) C129 1.1
 LDTP00266  Importin-5 (IPO5) C420 1.1
 LDTP11934  EH domain-containing protein 1 (EHD1) C138 1.1
 LDTP06242  Importin subunit beta-1 (KPNB1) C228 1.1
 LDTP03385  14-3-3 protein theta (YWHAQ) C134 1.1
 LDTP01574  Importin-7 (IPO7) C757 1.1
 LDTP09949  Transportin-1 (TNPO1) C103 1.1
 LDTP04707  Protein SEC13 homolog (SEC13) C245 1.1
 LDTP04662  Exportin-2 (CSE1L) C85 1.1
 LDTP01969  Transferrin receptor protein 1 (TFRC) C558 1.1
 LDTP05057  Small ribosomal subunit protein RACK1 (RACK1) C168 1.1
 LDTP05057  Small ribosomal subunit protein RACK1 (RACK1) C153 1.1
 LDTP09949  Transportin-1 (TNPO1) C285 1.1
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1) C590 1.1
 LDTP11877  Golgi resident protein GCP60 (ACBD3) C129 1.1
 LDTP04501  Importin subunit alpha-1 (KPNA2) C133 1.1
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1) C521 1.1
 LDTP00266  Importin-5 (IPO5) C733 1.1
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) C277 1.1
 LDTP05057  Small ribosomal subunit protein RACK1 (RACK1) C249 1.1
 LDTP03061  Cation-dependent mannose-6-phosphate receptor (M6PR) C244 1.1
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) C129 1.1
 LDTP02307  Annexin A5 (ANXA5) C316 1.1
 LDTP04662  Exportin-2 (CSE1L) C842 1.1
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) C59 1.1
 LDTP00244  Chloride intracellular channel protein 1 (CLIC1) C178 1.1
 LDTP09949  Transportin-1 (TNPO1) C790 1.1
 LDTP04501  Importin subunit alpha-1 (KPNA2) C272 1.1
 LDTP05252  Clathrin heavy chain 1 (CLTC) C753 1.1
 LDTP05252  Clathrin heavy chain 1 (CLTC) C934 1.0
 LDTP04662  Exportin-2 (CSE1L) C344 1.0
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1) C589 1.0
 LDTP03327  ATP synthase subunit alpha, mitochondrial (ATP5F1A) C294 1.0
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1) C366 1.0
 LDTP04707  Protein SEC13 homolog (SEC13) C234 1.0
 LDTP00244  Chloride intracellular channel protein 1 (CLIC1) C223 1.0
 LDTP09949  Transportin-1 (TNPO1) C142 1.0
 LDTP12142  Exportin-5 (XPO5) C941 1.0
 LDTP00266  Importin-5 (IPO5) C944 1.0
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) C159 1.0
 LDTP03546  Translocator protein (TSPO) C19 1.0
 LDTP05057  Small ribosomal subunit protein RACK1 (RACK1) C286 1.0
 LDTP01031  Importin subunit alpha-7 (KPNA6) C340 1.0
 LDTP11916  Tubulin beta-1 chain (TUBB1) C201 1.0
 LDTP04624  Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) C154 1.0
 LDTP05252  Clathrin heavy chain 1 (CLTC) C328 1.0
 LDTP11916  Tubulin beta-1 chain (TUBB1) C211 1.0
 LDTP04391  T-complex protein 1 subunit delta (CCT4) C120 1.0
 LDTP06462  Neutral amino acid transporter B(0) (SLC1A5) C39 1.0
 LDTP01133  Copine-3 (CPNE3) C506 1.0
 LDTP00266  Importin-5 (IPO5) C1078 1.0
 LDTP09149  ATP-binding cassette sub-family F member 1 (ABCF1) C365 1.0
 LDTP06242  Importin subunit beta-1 (KPNB1) C585 1.0
 LDTP04624  Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) C170 1.0
Transcription factor
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP05194  Enhancer of rudimentary homolog (ERH) C28 1.1
 LDTP03903  Signal transducer and activator of transcription 3 (STAT3) C259 1.1
 LDTP03970  Signal transducer and activator of transcription 6 (STAT6) C356 1.1
 LDTP07940  eIF5-mimic protein 2 (BZW1) C35 1.0
 LDTP03969  Signal transducer and activator of transcription 1-alpha/beta (STAT1) C255 1.0
 LDTP05577  FACT complex subunit SSRP1 (SSRP1) C200 0.9
Other
Click to Show/Hide to Show 170 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP03404  Microtubule-associated protein 4 (MAP4) C126 1.8
 LDTP04110  Small ribosomal subunit protein uS7 (RPS5) C155 1.2
 LDTP00119  Tubulin beta 8B (TUBB8B) C303 1.2
 LDTP12412  Reticulon-4 (RTN4) C1110 1.2
 LDTP10990  T-complex protein 1 subunit eta (CCT7) C326 1.2
 LDTP05024  Large ribosomal subunit protein uL1 (RPL10A) C74 1.2
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) C102 1.2
 LDTP13991  Serine-threonine kinase receptor-associated protein (STRAP) C305 1.2
 LDTP02109  Large ribosomal subunit protein uL10 (RPLP0) C27 1.2
 LDTP03815  Large ribosomal subunit protein uL4 (RPL4) C125 1.2
 LDTP04510  Rho GDP-dissociation inhibitor 1 (ARHGDIA) C79 1.1
 LDTP00766  Eukaryotic translation initiation factor 4 gamma 3 (EIF4G3) C928 1.1
 LDTP03554  Sorcin (SRI) C194 1.1
 LDTP04105  Large ribosomal subunit protein uL15 (RPL27A) C70 1.1
 LDTP10035  Proteasome assembly chaperone 2 (PSMG2) C178 1.1
 LDTP03367  Elongation factor 1-gamma (EEF1G) C194 1.1
 LDTP13813  Eukaryotic translation initiation factor 3 subunit L (EIF3L) C417 1.1
 LDTP05484  Proteasome activator complex subunit 1 (PSME1) C106 1.1
 LDTP03719  Serpin B6 (SERPINB6) C100 1.1
 LDTP13839  Nck-associated protein 1 (NCKAP1) C622 1.1
 LDTP06367  Poly(rC)-binding protein 2 (PCBP2) C217 1.1
 LDTP04249  T-complex protein 1 subunit gamma (CCT3) C366 1.1
 LDTP04355  Rab GDP dissociation inhibitor beta (GDI2) C414 1.1
 LDTP08018  Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) C513 1.1
 LDTP04249  T-complex protein 1 subunit gamma (CCT3) C182 1.1
 LDTP05024  Large ribosomal subunit protein uL1 (RPL10A) C66 1.1
 LDTP02809  Small ribosomal subunit protein uS5 (RPS2) C229 1.1
 LDTP03367  Elongation factor 1-gamma (EEF1G) C68 1.1
 LDTP04390  T-complex protein 1 subunit theta (CCT8) C244 1.1
 LDTP02037  Tubulin beta-4A chain (TUBB4A) C239 1.1
 LDTP02734  Endoplasmin (HSP90B1) C645 1.1
 LDTP04201  T-complex protein 1 subunit epsilon (CCT5) C253 1.1
 LDTP03865  Large ribosomal subunit protein uL3 (RPL3) C114 1.1
 LDTP01379  Ribosomal L1 domain-containing protein 1 (RSL1D1) C96 1.1
 LDTP04201  T-complex protein 1 subunit epsilon (CCT5) C429 1.1
 LDTP03825  Serpin B5 (SERPINB5) C34 1.1
 LDTP04997  Small ribosomal subunit protein eS4, X isoform (RPS4X) C41 1.1
 LDTP05026  Large ribosomal subunit protein uL5 (RPL11) C25 1.1
 LDTP03106  Cysteine and glycine-rich protein 1 (CSRP1) C167 1.1
 LDTP03846  Transgelin-2 (TAGLN2) C63 1.1
 LDTP00114  Putative annexin A2-like protein (ANXA2P2) C133 1.1
 LDTP06444  Microtubule-associated protein RP/EB family member 1 (MAPRE1) C228 1.1
 LDTP04106  Large ribosomal subunit protein uL18 (RPL5) C100 1.1
 LDTP04951  Nuclear transport factor 2 (NUTF2) C114 1.1
 LDTP05049  Dynein light chain 1, cytoplasmic (DYNLL1) C24 1.1
 LDTP02692  Plastin-3 (PLS3) C566 1.1
 LDTP04110  Small ribosomal subunit protein uS7 (RPS5) C172 1.1
 LDTP13519  Proteasome activator complex subunit 2 (PSME2) C91 1.1
 LDTP03620  Protein S100-A11 (S100A11) C13 1.1
 LDTP04952  Heterogeneous nuclear ribonucleoprotein K (HNRNPK) C145 1.1
 LDTP04201  T-complex protein 1 subunit epsilon (CCT5) C302 1.1
 LDTP04249  T-complex protein 1 subunit gamma (CCT3) C455 1.1
 LDTP08902  CDGSH iron-sulfur domain-containing protein 2 (CISD2) C92 1.1
 LDTP06367  Poly(rC)-binding protein 2 (PCBP2) C109 1.1
 LDTP00119  Tubulin beta 8B (TUBB8B) C127 1.1
 LDTP13479  Protein kinase C and casein kinase substrate in neurons protein 3 (PACSIN3) C42 1.1
 LDTP06598  Fascin (FSCN1) C80 1.1
 LDTP11421  Fanconi anemia group D2 protein (FANCD2) C729 1.1
 LDTP02595  Polyadenylate-binding protein 1 (PABPC1) C128 1.1
 LDTP03367  Elongation factor 1-gamma (EEF1G) C266 1.1
 LDTP05922  Dynactin subunit 2 (DCTN2) C240 1.1
 LDTP02944  Large ribosomal subunit protein uL30 (RPL7) C186 1.1
 LDTP05002  Small ribosomal subunit protein eS6 (RPS6) C12 1.1
 LDTP09821  Stalled ribosome sensor GCN1 (GCN1) C1482 1.1
 LDTP08735  Spartin (SPART) C499 1.1
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) C60 1.1
 LDTP16826  Translation initiation factor eIF2 assembly protein (CDC123) C151 1.1
 LDTP05484  Proteasome activator complex subunit 1 (PSME1) C101 1.1
 LDTP03321  Small ribosomal subunit protein eS12 (RPS12) C92 1.1
 LDTP03620  Protein S100-A11 (S100A11) C91 1.1
 LDTP10990  T-complex protein 1 subunit eta (CCT7) C450 1.1
 LDTP05113  T-complex protein 1 subunit beta (CCT2) C412 1.1
 LDTP04390  T-complex protein 1 subunit theta (CCT8) C148 1.1
 LDTP04997  Small ribosomal subunit protein eS4, X isoform (RPS4X) C181 1.1
 LDTP03888  T-complex protein 1 subunit zeta (CCT6A) C406 1.1
 LDTP03860  Stress-70 protein, mitochondrial (HSPA9) C317 1.1
 LDTP01011  Protein diaphanous homolog 1 (DIAPH1) C796 1.1
 LDTP03517  Large ribosomal subunit protein uL11 (RPL12) C162 1.1
 LDTP10990  T-complex protein 1 subunit eta (CCT7) C345 1.1
 LDTP00778  Band 4.1-like protein 2 (EPB41L2) C232 1.1
 LDTP03030  Annexin A7 (ANXA7) C363 1.1
 LDTP03871  Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) C123 1.1
 LDTP05027  Large ribosomal subunit protein uL2 (RPL8) C114 1.1
 LDTP06083  Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) C4438 1.1
 LDTP06366  Poly(rC)-binding protein 1 (PCBP1) C109 1.1
 LDTP12269  Pre-mRNA-splicing factor SYF1 (XAB2) C587 1.1
 LDTP05360  Large ribosomal subunit protein eL20 (RPL18A) C109 1.1
 LDTP03517  Large ribosomal subunit protein uL11 (RPL12) C141 1.1
 LDTP02354  Annexin A4 (ANXA4) C108 1.1
 LDTP04201  T-complex protein 1 subunit epsilon (CCT5) C440 1.1
 LDTP03364  Polypyrimidine tract-binding protein 1 (PTBP1) C251 1.1
 LDTP04249  T-complex protein 1 subunit gamma (CCT3) C213 1.1
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) C223 1.1
 LDTP03695  Heat shock 70 kDa protein 4 (HSPA4) C380 1.1
 LDTP04355  Rab GDP dissociation inhibitor beta (GDI2) C202 1.1
 LDTP02596  Proliferating cell nuclear antigen (PCNA) C135 1.1
 LDTP03888  T-complex protein 1 subunit zeta (CCT6A) C499 1.1
 LDTP05767  TAR DNA-binding protein 43 (TARDBP) C39 1.1
 LDTP02312  Small ribosomal subunit protein uS2 (RPSA) C148 1.1
 LDTP03846  Transgelin-2 (TAGLN2) C38 1.1
 LDTP03612  Bifunctional purine biosynthesis protein ATIC (ATIC) C241 1.1
 LDTP02934  T-complex protein 1 subunit alpha (TCP1) C385 1.1
 LDTP04390  T-complex protein 1 subunit theta (CCT8) C149 1.1
 LDTP01021  Perilipin-3 (PLIN3) C341 1.1
 LDTP06681  Inverted formin-2 (INF2) C38 1.1
 LDTP03695  Heat shock 70 kDa protein 4 (HSPA4) C290 1.0
 LDTP06366  Poly(rC)-binding protein 1 (PCBP1) C54 1.0
 LDTP03841  Hippocalcin-like protein 1 (HPCAL1) C185 1.0
 LDTP04106  Large ribosomal subunit protein uL18 (RPL5) C144 1.0
 LDTP00119  Tubulin beta 8B (TUBB8B) C354 1.0
 LDTP04964  Small ribosomal subunit protein eS8 (RPS8) C71 1.0
 LDTP02107  Large ribosomal subunit protein P1 (RPLP1) C61 1.0
 LDTP04975  Small ribosomal subunit protein uS17 (RPS11) C131 1.0
 LDTP03728  Large ribosomal subunit protein eL22 (RPL22) C25 1.0
 LDTP11575  Apoptosis inhibitor 5 (API5) C234 1.0
 LDTP02037  Tubulin beta-4A chain (TUBB4A) C211 1.0
 LDTP04952  Heterogeneous nuclear ribonucleoprotein K (HNRNPK) C132 1.0
 LDTP03574  Rab GDP dissociation inhibitor alpha (GDI1) C202 1.0
 LDTP02205  Tubulin beta chain (TUBB) C12 1.0
 LDTP05904  Tubulin beta-3 chain (TUBB3) C201 1.0
 LDTP02109  Large ribosomal subunit protein uL10 (RPLP0) C119 1.0
 LDTP02734  Endoplasmin (HSP90B1) C576 1.0
 LDTP04971  Small ribosomal subunit protein uS12 (RPS23) C90 1.0
 LDTP03618  14-3-3 protein sigma (SFN) C38 1.0
 LDTP04964  Small ribosomal subunit protein eS8 (RPS8) C72 1.0
 LDTP09843  Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) C123 1.0
 LDTP03695  Heat shock 70 kDa protein 4 (HSPA4) C417 1.0
 LDTP04586  Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1IP) C81 1.0
 LDTP02656  Ribonuclease inhibitor (RNH1) C96 1.0
 LDTP05904  Tubulin beta-3 chain (TUBB3) C211 1.0
 LDTP04887  Destrin (DSTN) C163 1.0
 LDTP02365  U2 small nuclear ribonucleoprotein A' (SNRPA1) C89 1.0
 LDTP05770  Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) C306 1.0
 LDTP02312  Small ribosomal subunit protein uS2 (RPSA) C163 1.0
 LDTP01534  Luc7-like protein 3 (LUC7L3) C43 1.0
 LDTP02037  Tubulin beta-4A chain (TUBB4A) C201 1.0
 LDTP03520  Phosphatidylethanolamine-binding protein 1 (PEBP1) C168 1.0
 LDTP02779  Ezrin (EZR) C117 1.0
 LDTP06598  Fascin (FSCN1) C61 1.0
 LDTP00720  Centromere/kinetochore protein zw10 homolog (ZW10) C568 1.0
 LDTP02692  Plastin-3 (PLS3) C104 1.0
 LDTP05008  Large ribosomal subunit protein uL14 (RPL23) C28 1.0
 LDTP00119  Tubulin beta 8B (TUBB8B) C129 1.0
 LDTP02683  Translationally-controlled tumor protein (TPT1) C28 1.0
 LDTP02809  Small ribosomal subunit protein uS5 (RPS2) C222 1.0
 LDTP03997  Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) C484 1.0
 LDTP13817  Nuclear migration protein nudC (NUDC) C188 1.0
 LDTP03997  Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) C1277 1.0
 LDTP14216  Coatomer subunit gamma-1 (COPG1) C129 1.0
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) C180 1.0
 LDTP04110  Small ribosomal subunit protein uS7 (RPS5) C66 1.0
 LDTP05259  Heterogeneous nuclear ribonucleoprotein U (HNRNPU) C389 1.0
 LDTP01251  Splicing factor 3B subunit 1 (SF3B1) C1035 1.0
 LDTP03367  Elongation factor 1-gamma (EEF1G) C210 1.0
 LDTP06376  Splicing factor 3B subunit 3 (SF3B3) C427 1.0
 LDTP05998  Tubulin beta-2A chain (TUBB2A) C129 1.0
 LDTP03554  Sorcin (SRI) C163 1.0
 LDTP00119  Tubulin beta 8B (TUBB8B) C129 1.0
 LDTP03815  Large ribosomal subunit protein uL4 (RPL4) C208 1.0
 LDTP02037  Tubulin beta-4A chain (TUBB4A) C239 1.0
 LDTP03395  Large ribosomal subunit protein uL16 (RPL10) C49 1.0
 LDTP02934  T-complex protein 1 subunit alpha (TCP1) C147 1.0
 LDTP04844  Actin-related protein 2/3 complex subunit 4 (ARPC4) C21 1.0
 LDTP10990  T-complex protein 1 subunit eta (CCT7) C29 1.0
 LDTP03846  Transgelin-2 (TAGLN2) C124 1.0
 LDTP01510  Zinc finger protein-like 1 (ZFPL1) C230 1.0
 LDTP05421  Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) C662 1.0
 LDTP13974  EKC/KEOPS complex subunit TPRKB (TPRKB) C167 0.9
 LDTP05770  Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) C291 0.9
 LDTP03967  Lamina-associated polypeptide 2, isoform alpha (TMPO) C570 0.9

References

1 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.