Details of the Target

General Information of Target

Target ID LDTP04586
Target Name Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1IP)
Gene Name PTTG1IP
Gene ID 754
Synonyms
C21orf1; C21orf3; Pituitary tumor-transforming gene 1 protein-interacting protein; Pituitary tumor-transforming gene protein-binding factor; PBF; PTTG-binding factor
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAPGVARGPTPYWRLRLGGAALLLLLIPVAAAQEPPGAACSQNTNKTCEECLKNVSCLWC
NTNKACLDYPVTSVLPPASLCKLSSARWGVCWVNFEALIITMSVVGGTLLLGIAICCCCC
CRRKRSRKPDRSEEKAMREREERRIRQEERRAEMKTRHDEIRKKYGLFKEENPYARFENN
Target Bioclass
Other
Subcellular location
Membrane
Function May facilitate PTTG1 nuclear translocation.
Uniprot ID
P53801
Ensemble ID
ENST00000330938.8
HGNC ID
HGNC:13524

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TH211
 Probe Info  		Y165(20.00)  LDD0260  [1]
STPyne
 Probe Info  		K155(7.20); K164(8.70); K169(7.29); K82(7.16)  LDD0277  [2]
ONAyne
 Probe Info  		K164(10.00)  LDD0275  [2]
JZ128-DTB
 Probe Info  		N.A.  LDD0462  [3]
THZ1-DTB
 Probe Info  		C81(1.03)  LDD0460  [3]
DBIA
 Probe Info  		C66(1.03); C81(1.03); C48(0.89); C51(0.89)  LDD0078  [4]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [5]
Acrolein
 Probe Info  		N.A.  LDD0217  [6]
AOyne
 Probe Info  		7.80  LDD0443  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C66(0.99); C81(0.99)  LDD1093  [4]
 LDCM0215  AC10 HCT 116 C66(1.00); C81(1.00)  LDD0532  [4]
 LDCM0216  AC100 PaTu 8988t C66(1.26); C81(1.26)  LDD1095  [4]
 LDCM0217  AC101 PaTu 8988t C66(1.19); C81(1.19)  LDD1096  [4]
 LDCM0218  AC102 PaTu 8988t C66(0.97); C81(0.97)  LDD1097  [4]
 LDCM0219  AC103 PaTu 8988t C66(1.09); C81(1.09)  LDD1098  [4]
 LDCM0220  AC104 PaTu 8988t C66(1.07); C81(1.07)  LDD1099  [4]
 LDCM0221  AC105 PaTu 8988t C66(1.08); C81(1.08)  LDD1100  [4]
 LDCM0222  AC106 PaTu 8988t C66(1.05); C81(1.05)  LDD1101  [4]
 LDCM0223  AC107 PaTu 8988t C66(1.34); C81(1.34)  LDD1102  [4]
 LDCM0224  AC108 PaTu 8988t C66(1.06); C81(1.06)  LDD1103  [4]
 LDCM0225  AC109 PaTu 8988t C66(0.96); C81(0.96)  LDD1104  [4]
 LDCM0226  AC11 HCT 116 C66(1.15); C81(1.15)  LDD0543  [4]
 LDCM0227  AC110 PaTu 8988t C66(1.28); C81(1.28)  LDD1106  [4]
 LDCM0228  AC111 PaTu 8988t C66(1.12); C81(1.12)  LDD1107  [4]
 LDCM0229  AC112 PaTu 8988t C66(1.29); C81(1.29)  LDD1108  [4]
 LDCM0230  AC113 PaTu 8988t C66(1.02); C81(1.02)  LDD1109  [4]
 LDCM0231  AC114 PaTu 8988t C66(0.73); C81(0.73)  LDD1110  [4]
 LDCM0232  AC115 PaTu 8988t C66(0.80); C81(0.80)  LDD1111  [4]
 LDCM0233  AC116 PaTu 8988t C66(1.08); C81(1.08)  LDD1112  [4]
 LDCM0234  AC117 PaTu 8988t C66(1.00); C81(1.00)  LDD1113  [4]
 LDCM0235  AC118 PaTu 8988t C66(0.99); C81(0.99)  LDD1114  [4]
 LDCM0236  AC119 PaTu 8988t C66(0.77); C81(0.77)  LDD1115  [4]
 LDCM0237  AC12 HCT 116 C66(0.99); C81(0.99)  LDD0554  [4]
 LDCM0238  AC120 PaTu 8988t C66(0.93); C81(0.93)  LDD1117  [4]
 LDCM0239  AC121 PaTu 8988t C66(0.93); C81(0.93)  LDD1118  [4]
 LDCM0240  AC122 PaTu 8988t C66(0.96); C81(0.96)  LDD1119  [4]
 LDCM0241  AC123 PaTu 8988t C66(0.81); C81(0.81)  LDD1120  [4]
 LDCM0242  AC124 PaTu 8988t C66(0.93); C81(0.93)  LDD1121  [4]
 LDCM0243  AC125 PaTu 8988t C66(1.02); C81(1.02)  LDD1122  [4]
 LDCM0244  AC126 PaTu 8988t C66(0.99); C81(0.99)  LDD1123  [4]
 LDCM0245  AC127 PaTu 8988t C66(1.08); C81(1.08)  LDD1124  [4]
 LDCM0246  AC128 PaTu 8988t C66(0.84); C81(0.84)  LDD1125  [4]
 LDCM0247  AC129 PaTu 8988t C66(0.90); C81(0.90)  LDD1126  [4]
 LDCM0249  AC130 PaTu 8988t C66(0.96); C81(0.96)  LDD1128  [4]
 LDCM0250  AC131 PaTu 8988t C66(0.93); C81(0.93)  LDD1129  [4]
 LDCM0251  AC132 PaTu 8988t C66(1.06); C81(1.06)  LDD1130  [4]
 LDCM0252  AC133 PaTu 8988t C66(1.09); C81(1.09)  LDD1131  [4]
 LDCM0253  AC134 PaTu 8988t C66(1.08); C81(1.08)  LDD1132  [4]
 LDCM0254  AC135 PaTu 8988t C66(0.96); C81(0.96)  LDD1133  [4]
 LDCM0255  AC136 PaTu 8988t C66(0.91); C81(0.91)  LDD1134  [4]
 LDCM0256  AC137 PaTu 8988t C66(0.89); C81(0.89)  LDD1135  [4]
 LDCM0257  AC138 PaTu 8988t C66(0.92); C81(0.92)  LDD1136  [4]
 LDCM0258  AC139 PaTu 8988t C66(0.76); C81(0.76)  LDD1137  [4]
 LDCM0259  AC14 HCT 116 C66(0.83); C81(0.83)  LDD0576  [4]
 LDCM0260  AC140 PaTu 8988t C66(0.90); C81(0.90)  LDD1139  [4]
 LDCM0261  AC141 PaTu 8988t C66(1.16); C81(1.16)  LDD1140  [4]
 LDCM0262  AC142 PaTu 8988t C66(0.88); C81(0.88)  LDD1141  [4]
 LDCM0263  AC143 HCT 116 C66(0.78); C81(0.78)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C66(0.91); C81(0.91)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C66(1.05); C81(1.05)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C66(0.83); C81(0.83)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C66(1.19); C81(1.19)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C66(1.18); C81(1.18)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C66(0.86); C81(0.86)  LDD0586  [4]
 LDCM0270  AC15 HCT 116 C66(1.13); C81(1.13)  LDD0587  [4]
 LDCM0271  AC150 HCT 116 C66(0.92); C81(0.92)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C66(1.11); C81(1.11)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C66(1.08); C81(1.08)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C66(1.06); C81(1.06)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C66(1.19); C81(1.19)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C66(0.90); C81(0.90)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C66(0.77); C81(0.77)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C66(0.92); C81(0.92)  LDD2161  [4]
 LDCM0276  AC17 HCT 116 C66(0.73); C81(0.73)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C66(0.84); C81(0.84)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C66(0.49); C81(0.49)  LDD0595  [4]
 LDCM0279  AC2 PaTu 8988t C66(1.08); C81(1.08)  LDD1158  [4]
 LDCM0280  AC20 HCT 116 C66(0.84); C81(0.84)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C66(0.71); C81(0.71)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C66(0.48); C81(0.48)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C66(0.60); C81(0.60)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C66(0.92); C81(0.92)  LDD0601  [4]
 LDCM0285  AC25 PaTu 8988t C66(0.70); C81(0.70)  LDD1164  [4]
 LDCM0286  AC26 PaTu 8988t C66(0.61); C81(0.61)  LDD1165  [4]
 LDCM0287  AC27 PaTu 8988t C66(0.66); C81(0.66)  LDD1166  [4]
 LDCM0288  AC28 PaTu 8988t C66(0.80); C81(0.80)  LDD1167  [4]
 LDCM0289  AC29 PaTu 8988t C66(0.74); C81(0.74)  LDD1168  [4]
 LDCM0290  AC3 PaTu 8988t C66(1.10); C81(1.10)  LDD1169  [4]
 LDCM0291  AC30 PaTu 8988t C66(0.76); C81(0.76)  LDD1170  [4]
 LDCM0292  AC31 PaTu 8988t C66(0.86); C81(0.86)  LDD1171  [4]
 LDCM0293  AC32 PaTu 8988t C66(0.97); C81(0.97)  LDD1172  [4]
 LDCM0294  AC33 PaTu 8988t C66(0.94); C81(0.94)  LDD1173  [4]
 LDCM0295  AC34 PaTu 8988t C66(0.78); C81(0.78)  LDD1174  [4]
 LDCM0296  AC35 PaTu 8988t C66(1.08); C81(1.08)  LDD1175  [4]
 LDCM0297  AC36 PaTu 8988t C66(0.82); C81(0.82)  LDD1176  [4]
 LDCM0298  AC37 PaTu 8988t C66(0.86); C81(0.86)  LDD1177  [4]
 LDCM0299  AC38 PaTu 8988t C66(1.06); C81(1.06)  LDD1178  [4]
 LDCM0300  AC39 PaTu 8988t C66(1.01); C81(1.01)  LDD1179  [4]
 LDCM0301  AC4 PaTu 8988t C66(0.83); C81(0.83)  LDD1180  [4]
 LDCM0302  AC40 PaTu 8988t C66(1.14); C81(1.14)  LDD1181  [4]
 LDCM0303  AC41 PaTu 8988t C66(1.10); C81(1.10)  LDD1182  [4]
 LDCM0304  AC42 PaTu 8988t C66(1.03); C81(1.03)  LDD1183  [4]
 LDCM0305  AC43 PaTu 8988t C66(1.09); C81(1.09)  LDD1184  [4]
 LDCM0306  AC44 PaTu 8988t C66(1.21); C81(1.21)  LDD1185  [4]
 LDCM0307  AC45 PaTu 8988t C66(0.96); C81(0.96)  LDD1186  [4]
 LDCM0308  AC46 PaTu 8988t C66(0.97); C81(0.97)  LDD1187  [4]
 LDCM0309  AC47 PaTu 8988t C66(0.83); C81(0.83)  LDD1188  [4]
 LDCM0310  AC48 PaTu 8988t C66(0.96); C81(0.96)  LDD1189  [4]
 LDCM0311  AC49 PaTu 8988t C66(1.11); C81(1.11)  LDD1190  [4]
 LDCM0312  AC5 PaTu 8988t C66(1.29); C81(1.29)  LDD1191  [4]
 LDCM0313  AC50 PaTu 8988t C66(1.26); C81(1.26)  LDD1192  [4]
 LDCM0314  AC51 PaTu 8988t C66(0.62); C81(0.62)  LDD1193  [4]
 LDCM0315  AC52 PaTu 8988t C66(1.02); C81(1.02)  LDD1194  [4]
 LDCM0316  AC53 PaTu 8988t C66(1.34); C81(1.34)  LDD1195  [4]
 LDCM0317  AC54 PaTu 8988t C66(1.19); C81(1.19)  LDD1196  [4]
 LDCM0318  AC55 PaTu 8988t C66(0.91); C81(0.91)  LDD1197  [4]
 LDCM0319  AC56 PaTu 8988t C66(0.99); C81(0.99)  LDD1198  [4]
 LDCM0320  AC57 HCT 116 C66(0.89); C81(0.89)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C66(1.02); C81(1.02)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C66(1.41); C81(1.41)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C66(1.01); C81(1.01)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C66(1.04); C81(1.04)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C66(1.19); C81(1.19)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C66(1.16); C81(1.16)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C66(0.94); C81(0.94)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C66(1.55); C81(1.55)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C66(0.84); C81(0.84)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C66(0.91); C81(0.91)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C66(0.92); C81(0.92)  LDD0648  [4]
 LDCM0332  AC68 PaTu 8988t C66(0.75); C81(0.75)  LDD1211  [4]
 LDCM0333  AC69 PaTu 8988t C66(0.79); C81(0.79)  LDD1212  [4]
 LDCM0334  AC7 HCT 116 C66(0.84); C81(0.84)  LDD0651  [4]
 LDCM0335  AC70 PaTu 8988t C66(0.77); C81(0.77)  LDD1214  [4]
 LDCM0336  AC71 PaTu 8988t C66(0.80); C81(0.80)  LDD1215  [4]
 LDCM0337  AC72 PaTu 8988t C66(0.74); C81(0.74)  LDD1216  [4]
 LDCM0338  AC73 PaTu 8988t C66(0.74); C81(0.74)  LDD1217  [4]
 LDCM0339  AC74 PaTu 8988t C66(0.75); C81(0.75)  LDD1218  [4]
 LDCM0340  AC75 PaTu 8988t C66(0.81); C81(0.81)  LDD1219  [4]
 LDCM0341  AC76 PaTu 8988t C66(0.95); C81(0.95)  LDD1220  [4]
 LDCM0342  AC77 PaTu 8988t C66(0.71); C81(0.71)  LDD1221  [4]
 LDCM0343  AC78 PaTu 8988t C66(0.65); C81(0.65)  LDD1222  [4]
 LDCM0344  AC79 PaTu 8988t C66(0.69); C81(0.69)  LDD1223  [4]
 LDCM0345  AC8 HCT 116 C66(1.10); C81(1.10)  LDD0662  [4]
 LDCM0346  AC80 PaTu 8988t C66(0.83); C81(0.83)  LDD1225  [4]
 LDCM0347  AC81 PaTu 8988t C66(0.70); C81(0.70)  LDD1226  [4]
 LDCM0348  AC82 PaTu 8988t C66(1.00); C81(1.00)  LDD1227  [4]
 LDCM0349  AC83 PaTu 8988t C66(0.92); C81(0.92)  LDD1228  [4]
 LDCM0350  AC84 PaTu 8988t C66(1.39); C81(1.39)  LDD1229  [4]
 LDCM0351  AC85 PaTu 8988t C66(0.86); C81(0.86)  LDD1230  [4]
 LDCM0352  AC86 PaTu 8988t C66(1.07); C81(1.07)  LDD1231  [4]
 LDCM0353  AC87 PaTu 8988t C66(0.91); C81(0.91)  LDD1232  [4]
 LDCM0354  AC88 PaTu 8988t C66(0.94); C81(0.94)  LDD1233  [4]
 LDCM0355  AC89 PaTu 8988t C66(0.99); C81(0.99)  LDD1234  [4]
 LDCM0357  AC90 PaTu 8988t C66(1.24); C81(1.24)  LDD1236  [4]
 LDCM0358  AC91 PaTu 8988t C66(1.09); C81(1.09)  LDD1237  [4]
 LDCM0359  AC92 PaTu 8988t C66(0.97); C81(0.97)  LDD1238  [4]
 LDCM0360  AC93 PaTu 8988t C66(1.04); C81(1.04)  LDD1239  [4]
 LDCM0361  AC94 PaTu 8988t C66(1.04); C81(1.04)  LDD1240  [4]
 LDCM0362  AC95 PaTu 8988t C66(1.05); C81(1.05)  LDD1241  [4]
 LDCM0363  AC96 PaTu 8988t C66(1.12); C81(1.12)  LDD1242  [4]
 LDCM0364  AC97 PaTu 8988t C66(1.27); C81(1.27)  LDD1243  [4]
 LDCM0365  AC98 PaTu 8988t C66(1.00); C81(1.00)  LDD1244  [4]
 LDCM0366  AC99 PaTu 8988t C66(1.00); C81(1.00)  LDD1245  [4]
 LDCM0248  AKOS034007472 HCT 116 C66(0.88); C81(0.88)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C66(0.91); C81(0.91)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C66(1.04); C81(1.04)  LDD0592  [4]
 LDCM0020  ARS-1620 HCC44 C66(1.03); C81(1.03); C48(0.89); C51(0.89)  LDD0078  [4]
 LDCM0367  CL1 HCT 116 C66(1.13); C81(1.13)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C66(1.15); C81(1.15)  LDD0685  [4]
 LDCM0369  CL100 PaTu 8988t C66(0.94); C81(0.94)  LDD1248  [4]
 LDCM0370  CL101 HCT 116 C66(1.32); C81(1.32)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C66(1.04); C81(1.04)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C66(1.38); C81(1.38)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C66(1.05); C81(1.05)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C66(1.17); C81(1.17)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C66(0.81); C81(0.81)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C66(0.88); C81(0.88)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C66(0.81); C81(0.81)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C66(0.94); C81(0.94)  LDD0695  [4]
 LDCM0379  CL11 HCT 116 C66(1.35); C81(1.35)  LDD0696  [4]
 LDCM0380  CL110 HCT 116 C66(0.82); C81(0.82)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C66(0.86); C81(0.86)  LDD0698  [4]
 LDCM0382  CL112 PaTu 8988t C66(0.94); C81(0.94)  LDD1261  [4]
 LDCM0383  CL113 PaTu 8988t C66(0.93); C81(0.93)  LDD1262  [4]
 LDCM0384  CL114 PaTu 8988t C66(1.08); C81(1.08)  LDD1263  [4]
 LDCM0385  CL115 PaTu 8988t C66(1.61); C81(1.61)  LDD1264  [4]
 LDCM0386  CL116 PaTu 8988t C66(0.71); C81(0.71)  LDD1265  [4]
 LDCM0387  CL117 PaTu 8988t C66(0.99); C81(0.99)  LDD1266  [4]
 LDCM0388  CL118 PaTu 8988t C66(1.20); C81(1.20)  LDD1267  [4]
 LDCM0389  CL119 PaTu 8988t C66(1.28); C81(1.28)  LDD1268  [4]
 LDCM0390  CL12 HCT 116 C66(1.71); C81(1.71)  LDD0707  [4]
 LDCM0391  CL120 PaTu 8988t C66(1.09); C81(1.09)  LDD1270  [4]
 LDCM0392  CL121 PaTu 8988t C66(1.13); C81(1.13)  LDD1271  [4]
 LDCM0393  CL122 PaTu 8988t C66(1.05); C81(1.05)  LDD1272  [4]
 LDCM0394  CL123 PaTu 8988t C66(1.48); C81(1.48)  LDD1273  [4]
 LDCM0395  CL124 PaTu 8988t C66(1.33); C81(1.33)  LDD1274  [4]
 LDCM0396  CL125 HCT 116 C66(1.04); C81(1.04)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C66(1.59); C81(1.59)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C66(1.45); C81(1.45)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C66(1.26); C81(1.26)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C66(1.18); C81(1.18)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C66(1.51); C81(1.51)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C66(1.93); C81(1.93)  LDD0719  [4]
 LDCM0403  CL16 HCT 116 C66(1.33); C81(1.33)  LDD0720  [4]
 LDCM0404  CL17 HCT 116 C66(1.23); C81(1.23)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C66(1.07); C81(1.07)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C66(1.00); C81(1.00)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C66(1.71); C81(1.71)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C66(1.11); C81(1.11)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C66(1.24); C81(1.24)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C66(1.43); C81(1.43)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C66(1.06); C81(1.06)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C66(1.29); C81(1.29)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C66(1.46); C81(1.46)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C66(1.27); C81(1.27)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C66(1.56); C81(1.56)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C66(1.29); C81(1.29)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C66(1.17); C81(1.17)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C66(1.72); C81(1.72)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C66(0.98); C81(0.98)  LDD0736  [4]
 LDCM0420  CL31 HEK-293T C66(0.84)  LDD1018  [4]
 LDCM0421  CL32 HEK-293T C66(0.73)  LDD1019  [4]
 LDCM0422  CL33 HEK-293T C66(0.59)  LDD1020  [4]
 LDCM0423  CL34 HEK-293T C66(0.87)  LDD1021  [4]
 LDCM0424  CL35 HEK-293T C66(0.71)  LDD1022  [4]
 LDCM0425  CL36 HEK-293T C66(0.72)  LDD1023  [4]
 LDCM0426  CL37 HEK-293T C66(0.74)  LDD1024  [4]
 LDCM0428  CL39 HEK-293T C66(0.42)  LDD1026  [4]
 LDCM0429  CL4 HCT 116 C66(2.16); C81(2.16)  LDD0746  [4]
 LDCM0430  CL40 HEK-293T C66(0.58)  LDD1028  [4]
 LDCM0431  CL41 HEK-293T C66(0.40)  LDD1029  [4]
 LDCM0432  CL42 HEK-293T C66(0.46)  LDD1030  [4]
 LDCM0433  CL43 HEK-293T C66(0.47)  LDD1031  [4]
 LDCM0434  CL44 HEK-293T C66(0.68)  LDD1032  [4]
 LDCM0435  CL45 HEK-293T C66(0.45)  LDD1033  [4]
 LDCM0436  CL46 HCT 116 C66(1.05); C81(1.05)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C66(1.10); C81(1.10)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C66(0.95); C81(0.95)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C66(1.12); C81(1.12)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C66(1.13); C81(1.13)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C66(1.00); C81(1.00)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C66(0.93); C81(0.93)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C66(1.01); C81(1.01)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C66(1.07); C81(1.07)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C66(1.25); C81(1.25)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C66(0.92); C81(0.92)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C66(1.25); C81(1.25)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C66(0.68); C81(0.68)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C66(0.95); C81(0.95)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C66(1.22); C81(1.22)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C66(1.54); C81(1.54)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C66(1.33); C81(1.33)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C66(0.96); C81(0.96)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C66(1.05); C81(1.05)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C66(1.09); C81(1.09)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C66(1.34); C81(1.34)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C66(0.96); C81(0.96)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C66(1.28); C81(1.28)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C66(1.15); C81(1.15)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C66(1.39); C81(1.39)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C66(1.44); C81(1.44)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C66(1.41); C81(1.41)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C66(1.07); C81(1.07)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C66(1.25); C81(1.25)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C66(1.05); C81(1.05)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C66(1.13); C81(1.13)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C66(1.20); C81(1.20)  LDD0784  [4]
 LDCM0469  CL76 HEK-293T C66(1.27)  LDD1067  [4]
 LDCM0470  CL77 HEK-293T C66(1.69)  LDD1068  [4]
 LDCM0471  CL78 HEK-293T C66(2.33)  LDD1069  [4]
 LDCM0472  CL79 HEK-293T C66(1.26)  LDD1070  [4]
 LDCM0473  CL8 HCT 116 C66(1.27); C81(1.27)  LDD0790  [4]
 LDCM0474  CL80 HEK-293T C66(1.69)  LDD1072  [4]
 LDCM0475  CL81 HEK-293T C66(1.41)  LDD1073  [4]
 LDCM0476  CL82 HEK-293T C66(1.10)  LDD1074  [4]
 LDCM0477  CL83 HEK-293T C66(1.09)  LDD1075  [4]
 LDCM0478  CL84 HEK-293T C66(1.09)  LDD1076  [4]
 LDCM0479  CL85 HEK-293T C66(1.55)  LDD1077  [4]
 LDCM0480  CL86 HEK-293T C66(2.38)  LDD1078  [4]
 LDCM0481  CL87 HEK-293T C66(1.24)  LDD1079  [4]
 LDCM0482  CL88 HEK-293T C66(0.85)  LDD1080  [4]
 LDCM0483  CL89 HEK-293T C66(1.44)  LDD1081  [4]
 LDCM0484  CL9 HCT 116 C66(1.54); C81(1.54)  LDD0801  [4]
 LDCM0485  CL90 HEK-293T C66(0.90)  LDD1083  [4]
 LDCM0486  CL91 PaTu 8988t C66(0.82); C81(0.82)  LDD1365  [4]
 LDCM0487  CL92 PaTu 8988t C66(1.51); C81(1.51)  LDD1366  [4]
 LDCM0488  CL93 PaTu 8988t C66(1.25); C81(1.25)  LDD1367  [4]
 LDCM0489  CL94 PaTu 8988t C66(0.95); C81(0.95)  LDD1368  [4]
 LDCM0490  CL95 PaTu 8988t C66(1.29); C81(1.29)  LDD1369  [4]
 LDCM0491  CL96 PaTu 8988t C66(1.13); C81(1.13)  LDD1370  [4]
 LDCM0492  CL97 PaTu 8988t C66(1.13); C81(1.13)  LDD1371  [4]
 LDCM0493  CL98 PaTu 8988t C66(1.03); C81(1.03)  LDD1372  [4]
 LDCM0494  CL99 PaTu 8988t C66(1.20); C81(1.20)  LDD1373  [4]
 LDCM0495  E2913 HEK-293T C81(1.00); C60(1.05)  LDD1698  [8]
 LDCM0468  Fragment33 HCT 116 C66(1.54); C81(1.54)  LDD0785  [4]
 LDCM0427  Fragment51 HEK-293T C66(0.50)  LDD1025  [4]
 LDCM0179  JZ128 PC-3 N.A.  LDD0462  [3]
 LDCM0022  KB02 HEK-293T C81(1.04); C60(0.91)  LDD1492  [8]
 LDCM0023  KB03 HEK-293T C81(0.93); C60(0.96)  LDD1497  [8]
 LDCM0024  KB05 HEK-293T C81(0.91); C60(0.98)  LDD1502  [8]
 LDCM0109  NEM HeLa N.A.  LDD0223  [6]
 LDCM0021  THZ1 HeLa S3 C81(1.03)  LDD0460  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Kallikrein-6 (KLK6) Peptidase S1 family Q92876
Prostaglandin G/H synthase 1 (PTGS1) Prostaglandin G/H synthase family P23219
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Alpha-crystallin A chain (CRYAA) Small heat shock protein (HSP20) family P02489
Transmembrane protein 106C (TMEM106C) TMEM106 family Q9BVX2
Renin receptor (ATP6AP2) . O75787
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Amphoterin-induced protein 1 (AMIGO1) AMIGO family Q86WK6
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tumor necrosis factor ligand superfamily member 14 (TNFSF14) Tumor necrosis factor family O43557
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Low-density lipoprotein receptor class A domain-containing protein 1 (LDLRAD1) LDLR family Q5T700
Beta-sarcoglycan (SGCB) Sarcoglycan beta/delta/gamma/zeta family Q16585
C-type lectin domain family 7 member A (CLEC7A) . Q9BXN2

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
6 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402