Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0179
Competitor Name
JZ128
Synonyms
SCHEMBL18313108; BDBM464102; US10787436, Compound I-40; PD135285
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 545.6
Lipid-water partition coefficient (xlogp) 4.5
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C32H31N7O2
IUPAC Name
4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[4-(4-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide
Canonical SMILES
CC1=C2C(=CC=C1)NC=C2C3=NC(=NC=C3)NC4=CC(=CC=C4)NC(=O)C5=CC=C(C=C5)NC(=O)C=CCN(C)C
InChI
InChI=1S/C32H31N7O2/c1-21-7-4-10-28-30(21)26(20-34-28)27-16-17-33-32(38-27)37-25-9-5-8-24(19-25)36-31(41)22-12-14-23(15-13-22)35-29(40)11-6-18-39(2)3/h4-17,19-20,34H,18H2,1-3H3,(H,35,40)(H,36,41)(H,33,37,38)/b11-6+
InChIKey
SEEVXFIEBQXBPA-IZZDOVSWSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
JZ128-DTB
 Probe Info  		2 uM Human prostate carcinoma cell lysate (PC-3) [1]

Target(s) List of this Competitor

185 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) LDTP09542 .  LDD0462 
1-phosphatidylinositol 3-phosphate 5-kinase (PIKFYVE) LDTP13873 .  LDD0462 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 .; .  LDD0462 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 .; .  LDD0462 
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1) LDTP05761 .  LDD0462 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 .  LDD0462 
6-phosphogluconolactonase (PGLS) LDTP14535 .  LDD0462 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 .; .; .  LDD0462 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 .  LDD0462 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 .  LDD0462 
Actin, alpha skeletal muscle (ACTA1) LDTP05073 .  LDD0462 
Actin, cytoplasmic 1 (ACTB) LDTP04876 .; .  LDD0462 
Acyl-coenzyme A diphosphatase FITM2 (FITM2) LDTP08943 .  LDD0462 
Adenosine kinase (ADK) LDTP04689 .  LDD0462 
ADP-ribosylation factor 1 (ARF1) LDTP05192 .  LDD0462 
ADP-ribosylation factor 4 (ARF4) LDTP02942 .  LDD0462 
ADP-ribosylation factor-related protein 1 (ARFRP1) LDTP05982 .; .  LDD0462 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 .  LDD0462 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 .  LDD0462 
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) LDTP04253 .; .  LDD0462 
Alpha-enolase (ENO1) LDTP02159 .; .; .  LDD0462 
Antigen peptide transporter 2 (TAP2) LDTP05409 .  LDD0462 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 .  LDD0462 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 .  LDD0462 
Atlastin-3 (ATL3) LDTP07362 .  LDD0462 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 .  LDD0462 
ATP-dependent RNA helicase A (DHX9) LDTP05550 .  LDD0462 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 .; .  LDD0462 
Calpain-1 catalytic subunit (CAPN1) LDTP02204 .  LDD0462 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 .; .  LDD0462 
Cathepsin B (CTSB) LDTP02223 .  LDD0462 
Cell division control protein 42 homolog (CDC42) LDTP04886 .  LDD0462 
Citrate synthase, mitochondrial (CS) LDTP01205 .  LDD0462 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 .  LDD0462 
Cyclin-dependent kinase 12 (CDK12) LDTP12852 .  LDD0462 
Cytidine deaminase (CDA) LDTP03642 .  LDD0462 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 .; .  LDD0462 
Cytochrome c oxidase subunit 1 (MT-CO1) LDTP01772 .  LDD0462 
Cytochrome c oxidase subunit NDUFA4 (NDUFA4) LDTP00293 .  LDD0462 
Cytochrome P450 1B1 (CYP1B1) LDTP06608 .  LDD0462 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 .; .; .  LDD0462 
DCN1-like protein 5 (DCUN1D5) LDTP11199 .  LDD0462 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 .; .  LDD0462 
Dihydroxyacetone phosphate acyltransferase (GNPAT) LDTP00577 .  LDD0462 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 .  LDD0462 
DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C) LDTP12539 .  LDD0462 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 .  LDD0462 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 .; .; . ...  LDD0462 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LDTP13087 .  LDD0462 
Dolichyl-phosphate beta-glucosyltransferase (ALG5) LDTP14214 .  LDD0462 
Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7) LDTP00414 .  LDD0462 
Dynamin-1-like protein (DNM1L) LDTP00273 .  LDD0462 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 .  LDD0462 
E3 ubiquitin-protein ligase RNF149 (RNF149) LDTP09079 .  LDD0462 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 .; .; . ...  LDD0462 
Elongation factor 2 (EEF2) LDTP02672 .; .; . ...  LDD0462 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 .; .  LDD0462 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 .  LDD0462 
Ephrin type-A receptor 2 (EPHA2) LDTP03474 .  LDD0462 
Epithelial discoidin domain-containing receptor 1 (DDR1) LDTP05554 .  LDD0462 
ERO1-like protein alpha (ERO1A) LDTP10386 .; .; .  LDD0462 
Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) LDTP03915 .  LDD0462 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 .; .; .  LDD0462 
Fatty acid synthase (FASN) LDTP04243 .  LDD0462 
Fructosamine-3-kinase (FN3K) LDTP11904 .  LDD0462 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 .; .; .  LDD0462 
Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1) LDTP10264 .  LDD0462 
Glucose-6-phosphatase 3 (G6PC3) LDTP11243 .  LDD0462 
Glucose-6-phosphate isomerase (GPI) LDTP02162 .  LDD0462 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 .  LDD0462 
Glutaryl-CoA dehydrogenase, mitochondrial (GCDH) LDTP09939 .  LDD0462 
Glutathione S-transferase P (GSTP1) LDTP02333 .  LDD0462 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 .; .  LDD0462 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 .  LDD0462 
GTP-binding nuclear protein Ran (RAN) LDTP05007 .  LDD0462 
GTP-binding protein SAR1a (SAR1A) LDTP12470 .  LDD0462 
Heme oxygenase 2 (HMOX2) LDTP03540 .  LDD0462 
Hepatocyte growth factor receptor (MET) LDTP02286 .  LDD0462 
Hexokinase-1 (HK1) LDTP02991 .; .  LDD0462 
Hexokinase-2 (HK2) LDTP04531 .; .  LDD0462 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 .  LDD0462 
Holocytochrome c-type synthase (HCCS) LDTP04581 .  LDD0462 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 .  LDD0462 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 .  LDD0462 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 .  LDD0462 
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) LDTP00885 .  LDD0462 
Ketosamine-3-kinase (FN3KRP) LDTP16025 .  LDD0462 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 .; .; .  LDD0462 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 .  LDD0462 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 .  LDD0462 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 .  LDD0462 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 .  LDD0462 
Lysophospholipid acyltransferase 2 (MBOAT2) LDTP07867 .  LDD0462 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 .  LDD0462 
Macrophage migration inhibitory factor (MIF) LDTP02713 .  LDD0462 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 .; .; . ...  LDD0462 
Matrix metalloproteinase-14 (MMP14) LDTP04352 .  LDD0462 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 .  LDD0462 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 .  LDD0462 
NAD(P)H-hydrate epimerase (NAXE) LDTP09110 .; .  LDD0462 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 .  LDD0462 
Non-receptor tyrosine-protein kinase TNK1 (TNK1) LDTP05884 .  LDD0462 
Nucleoside diphosphate kinase A (NME1) LDTP02796 .; .  LDD0462 
Ornithine aminotransferase, mitochondrial (OAT) LDTP02021 .  LDD0462 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 .  LDD0462 
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF) LDTP03534 .  LDD0462 
Peroxiredoxin-1 (PRDX1) LDTP05503 .  LDD0462 
Peroxiredoxin-2 (PRDX2) LDTP03626 .  LDD0462 
Peroxiredoxin-5, mitochondrial (PRDX5) LDTP03512 .  LDD0462 
Peroxiredoxin-6 (PRDX6) LDTP03510 .; .  LDD0462 
Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 .  LDD0462 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 .  LDD0462 
Phosphoglucomutase-1 (PGM1) LDTP03818 .; .  LDD0462 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 .; .; . ...  LDD0462 
Phospholipid scramblase 1 (PLSCR1) LDTP00558 .  LDD0462 
Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) LDTP06119 .; .  LDD0462 
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein (ASMTL) LDTP01647 .  LDD0462 
Prostaglandin E synthase (PTGES) LDTP00407 .  LDD0462 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 .; .; .  LDD0462 
Protein disulfide-isomerase A6 (PDIA6) LDTP06314 .  LDD0462 
Protein NDRG1 (NDRG1) LDTP09810 .  LDD0462 
Protein phosphatase 1G (PPM1G) LDTP00616 .  LDD0462 
Protein phosphatase methylesterase 1 (PPME1) LDTP14092 .  LDD0462 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 .; .; . ...  LDD0462 
Proto-oncogene tyrosine-protein kinase Src (SRC) LDTP02638 .  LDD0462 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 .; .; .  LDD0462 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 .  LDD0462 
Pyruvate kinase PKM (PKM) LDTP02733 .; .  LDD0462 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 .; .  LDD0462 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 .; .  LDD0462 
Ras-related protein Rab-13 (RAB13) LDTP04401 .  LDD0462 
Ras-related protein Rap-1b (RAP1B) LDTP04910 .  LDD0462 
Ras-related protein Rap-2b (RAP2B) LDTP04911 .  LDD0462 
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) LDTP00751 .; .; .  LDD0462 
Retinaldehyde dehydrogenase 3 (ALDH1A3) LDTP04134 .; .; . ...  LDD0462 
Retinol dehydrogenase 10 (RDH10) LDTP08722 .  LDD0462 
Retinol dehydrogenase 14 (RDH14) LDTP12180 .  LDD0462 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 .  LDD0462 
Rho-related GTP-binding protein RhoF (RHOF) LDTP12178 .  LDD0462 
Rho-related GTP-binding protein RhoG (RHOG) LDTP05195 .  LDD0462 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 .  LDD0462 
RNA cytidine acetyltransferase (NAT10) LDTP11690 .; .  LDD0462 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 .; .; .  LDD0462 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 .; .  LDD0462 
Serine/threonine-protein kinase 24 (STK24) LDTP14240 .  LDD0462 
Serine/threonine-protein kinase N3 (PKN3) LDTP07546 .  LDD0462 
Serine/threonine-protein kinase RIO2 (RIOK2) LDTP11299 .  LDD0462 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 .; .; . ...  LDD0462 
Short-chain dehydrogenase/reductase 3 (DHRS3) LDTP01349 .  LDD0462 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 .; .  LDD0462 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 .  LDD0462 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 .  LDD0462 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 .  LDD0462 
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (SUCLA2) LDTP13077 .  LDD0462 
Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) LDTP04438 .  LDD0462 
Telomerase RNA component interacting RNase (TRIR) LDTP11055 .  LDD0462 
Thioredoxin (TXN) LDTP02502 .  LDD0462 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 .  LDD0462 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 .  LDD0462 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 .; .  LDD0462 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 .; .; . ...  LDD0462 
Transforming protein RhoA (RHOA) LDTP04927 .; .  LDD0462 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 .; .; .  LDD0462 
Translin (TSN) LDTP06427 .  LDD0462 
Triokinase/FMN cyclase (TKFC) LDTP06779 .  LDD0462 
Triosephosphate isomerase (TPI1) LDTP04851 .  LDD0462 
Tripartite motif-containing protein 16 (TRIM16) LDTP01570 .  LDD0462 
tRNA methyltransferase 10 homolog C (TRMT10C) LDTP07937 .  LDD0462 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 .; .; .  LDD0462 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 .  LDD0462 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 .; .  LDD0462 
Tubulin alpha-3C chain (TUBA3C) LDTP02452 .; .; .  LDD0462 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 .  LDD0462 
Tyrosine-protein kinase JAK1 (JAK1) LDTP03230 .  LDD0462 
Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3) LDTP12908 .  LDD0462 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 .  LDD0462 
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1) LDTP04442 .  LDD0462 
Ubiquitin-conjugating enzyme E2 D2 (UBE2D2) LDTP05010 .  LDD0462 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 .; .; .  LDD0462 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 .  LDD0462 
Ubiquitin-like-conjugating enzyme ATG3 (ATG3) LDTP12599 .  LDD0462 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 .  LDD0462 
Valine--tRNA ligase (VARS1) LDTP03366 .; .; . ...  LDD0462 
Vitamin K epoxide reductase complex subunit 1 (VKORC1) LDTP11070 .; .  LDD0462 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 .  LDD0462 
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⏷ Show the Full List of 185 Enzyme
77 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein theta (YWHAQ) LDTP03385 .; .  LDD0462 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 .  LDD0462 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 .; .  LDD0462 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 .; .  LDD0462 
Annexin A11 (ANXA11) LDTP04393 .  LDD0462 
Annexin A2 (ANXA2) LDTP02199 .; .  LDD0462 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 .  LDD0462 
Cadherin-1 (CDH1) LDTP02634 .; .  LDD0462 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 .; .  LDD0462 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 .  LDD0462 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 .; .; .  LDD0462 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 .  LDD0462 
Clathrin heavy chain 1 (CLTC) LDTP05252 .; .; . ...  LDD0462 
Clathrin heavy chain 2 (CLTCL1) LDTP04578 .  LDD0462 
Copine-3 (CPNE3) LDTP01133 .  LDD0462 
Cytochrome c oxidase assembly protein COX20, mitochondrial (COX20) LDTP07053 .  LDD0462 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 .  LDD0462 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 .  LDD0462 
EH domain-containing protein 1 (EHD1) LDTP11934 .  LDD0462 
Exportin-1 (XPO1) LDTP00501 .; .; . ...  LDD0462 
Exportin-2 (CSE1L) LDTP04662 .; .  LDD0462 
Exportin-5 (XPO5) LDTP12142 .; .; .  LDD0462 
Exportin-7 (XPO7) LDTP13335 .; .  LDD0462 
Exportin-T (XPOT) LDTP00810 .; .  LDD0462 
Extended synaptotagmin-1 (ESYT1) LDTP11161 .  LDD0462 
Fatty acid-binding protein 5 (FABP5) LDTP05292 .; .  LDD0462 
Filamin-A (FLNA) LDTP03107 .; .  LDD0462 
Filamin-B (FLNB) LDTP01197 .; .  LDD0462 
Golgi resident protein GCP60 (ACBD3) LDTP11877 .  LDD0462 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 .  LDD0462 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 .  LDD0462 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 .  LDD0462 
Importin subunit alpha-7 (KPNA6) LDTP01031 .  LDD0462 
Importin subunit beta-1 (KPNB1) LDTP06242 .; .; .  LDD0462 
Importin-4 (IPO4) LDTP09515 .; .; . ...  LDD0462 
Importin-5 (IPO5) LDTP00266 .; .; . ...  LDD0462 
Importin-7 (IPO7) LDTP01574 .; .  LDD0462 
Integrin beta-1 (ITGB1) LDTP02122 .  LDD0462 
Kunitz-type protease inhibitor 2 (SPINT2) LDTP00728 .; .  LDD0462 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 .; .; .  LDD0462 
Low-density lipoprotein receptor (LDLR) LDTP01829 .  LDD0462 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 .  LDD0462 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 .  LDD0462 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 .  LDD0462 
MICOS complex subunit MIC26 (APOO) LDTP11250 .  LDD0462 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 .  LDD0462 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 .  LDD0462 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 .; .  LDD0462 
Mitochondrial potassium channel ATP-binding subunit (ABCB8) LDTP12644 .  LDD0462 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 .  LDD0462 
Neutral amino acid transporter B(0) (SLC1A5) LDTP06462 .; .  LDD0462 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 .  LDD0462 
Nucleoporin NDC1 (NDC1) LDTP11213 .  LDD0462 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 .  LDD0462 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 .  LDD0462 
Peroxisomal membrane protein PEX13 (PEX13) LDTP09948 .  LDD0462 
Phospholipid scramblase 3 (PLSCR3) LDTP12548 .; .; .  LDD0462 
Podocalyxin (PODXL) LDTP00321 .  LDD0462 
Programmed cell death protein 6 (PDCD6) LDTP01180 .  LDD0462 
Prohibitin 1 (PHB1) LDTP03717 .  LDD0462 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 .  LDD0462 
Rab5 GDP/GTP exchange factor (RABGEF1) LDTP13369 .  LDD0462 
Sideroflexin-1 (SFXN1) LDTP12090 .  LDD0462 
SNARE-associated protein Snapin (SNAPIN) LDTP01558 .  LDD0462 
Sodium- and chloride-dependent GABA transporter 3 (SLC6A11) LDTP04159 .  LDD0462 
Solute carrier family 12 member 9 (SLC12A9) LDTP11397 .  LDD0462 
Sorting nexin-1 (SNX1) LDTP05938 .  LDD0462 
Stomatin-like protein 2, mitochondrial (STOML2) LDTP13416 .  LDD0462 
Synaptosomal-associated protein 23 (SNAP23) LDTP00198 .  LDD0462 
Talin-1 (TLN1) LDTP14031 .; .  LDD0462 
Translocator protein (TSPO) LDTP03546 .  LDD0462 
Transportin-1 (TNPO1) LDTP09949 .; .; . ...  LDD0462 
Transportin-3 (TNPO3) LDTP14133 .  LDD0462 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 .  LDD0462 
Vezatin (VEZT) LDTP12191 .  LDD0462 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 .; .  LDD0462 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 .  LDD0462 
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⏷ Show the Full List of 77 Transporter and channel
4 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
eIF5-mimic protein 2 (BZW1) LDTP07940 .  LDD0462 
Enhancer of rudimentary homolog (ERH) LDTP05194 .  LDD0462 
Homeobox protein cut-like 1 (CUX1) LDTP03874 .  LDD0462 
Max-like protein X (MLX) LDTP13255 .  LDD0462 
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1 GPCR Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Adhesion G protein-coupled receptor E5 (ADGRE5) LDTP04221 .  LDD0462 
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4 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
HLA class I histocompatibility antigen, A alpha chain (HLA-A) LDTP02040 .  LDD0462 
HLA class I histocompatibility antigen, B alpha chain (HLA-B) LDTP01913 .  LDD0462 
Myelin protein zero-like protein 1 (MPZL1) LDTP01559 .  LDD0462 
Myelin protein zero-like protein 3 (MPZL3) LDTP15152 .  LDD0462 
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1 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CKLF-like MARVEL transmembrane domain-containing protein 7 (CMTM7) LDTP10323 .  LDD0462 
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166 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein sigma (SFN) LDTP03618 .  LDD0462 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 .  LDD0462 
Actin-related protein 3 (ACTR3) LDTP04902 .  LDD0462 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 .  LDD0462 
Alpha-actinin-1 (ACTN1) LDTP02631 .; .; . ...  LDD0462 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 .  LDD0462 
Ankyrin repeat and KH domain-containing protein 1 (ANKHD1) LDTP08573 .  LDD0462 
Annexin A3 (ANXA3) LDTP02620 .  LDD0462 
Annexin A4 (ANXA4) LDTP02354 .  LDD0462 
Annexin A7 (ANXA7) LDTP03030 .  LDD0462 
Apoptosis inhibitor 5 (API5) LDTP11575 .  LDD0462 
BET1 homolog (BET1) LDTP00555 .  LDD0462 
Beta-catenin-like protein 1 (CTNNBL1) LDTP09733 .  LDD0462 
Biorientation of chromosomes in cell division protein 1 (BOD1) LDTP10419 .  LDD0462 
BRCA2 and CDKN1A-interacting protein (BCCIP) LDTP13030 .  LDD0462 
BSD domain-containing protein 1 (BSDC1) LDTP16116 .  LDD0462 
Calcium homeostasis endoplasmic reticulum protein (CHERP) LDTP08570 .  LDD0462 
Calpain small subunit 1 (CAPNS1) LDTP02047 .  LDD0462 
Calpastatin (CAST) LDTP03079 .  LDD0462 
Catenin beta-1 (CTNNB1) LDTP03712 .  LDD0462 
CD99 antigen (CD99) LDTP02715 .  LDD0462 
Cellular retinoic acid-binding protein 2 (CRABP2) LDTP03482 .  LDD0462 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 .  LDD0462 
Ceramide-1-phosphate transfer protein (CPTP) LDTP07159 .  LDD0462 
Coatomer subunit beta (COPB1) LDTP04570 .  LDD0462 
Coatomer subunit gamma-1 (COPG1) LDTP14216 .  LDD0462 
Cofilin-1 (CFL1) LDTP03244 .  LDD0462 
Connector enhancer of kinase suppressor of ras 1 (CNKSR1) LDTP10001 .  LDD0462 
Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 .  LDD0462 
COP9 signalosome complex subunit 1 (GPS1) LDTP05746 .  LDD0462 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 .  LDD0462 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 .; .; .  LDD0462 
DnaJ homolog subfamily C member 9 (DNAJC9) LDTP09721 .  LDD0462 
Dynein axonemal assembly factor 5 (DNAAF5) LDTP08387 .  LDD0462 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 .; .  LDD0462 
Elongation factor 1-beta (EEF1B2) LDTP03283 .  LDD0462 
Elongation factor 1-delta (EEF1D) LDTP03499 .  LDD0462 
Elongation factor 1-gamma (EEF1G) LDTP03367 .; .; .  LDD0462 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 .  LDD0462 
Endoplasmin (HSP90B1) LDTP02734 .; .  LDD0462 
Ephrin-B1 (EFNB1) LDTP05222 .  LDD0462 
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2) LDTP11998 .  LDD0462 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 .  LDD0462 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 .  LDD0462 
Eukaryotic translation initiation factor 3 subunit K (EIF3K) LDTP13143 .  LDD0462 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 .  LDD0462 
Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) LDTP05421 .; .  LDD0462 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 .  LDD0462 
Fascin (FSCN1) LDTP06598 .; .  LDD0462 
FH1/FH2 domain-containing protein 1 (FHOD1) LDTP14195 .  LDD0462 
Galectin-1 (LGALS1) LDTP02341 .; .  LDD0462 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 .  LDD0462 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7) LDTP14469 .  LDD0462 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 .  LDD0462 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 .; .  LDD0462 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 .  LDD0462 
Hippocalcin-like protein 1 (HPCAL1) LDTP03841 .  LDD0462 
Hsp70-binding protein 1 (HSPBP1) LDTP12914 .  LDD0462 
Integrator complex subunit 1 (INTS1) LDTP08785 .  LDD0462 
Integrator complex subunit 15 (INTS15) LDTP18217 .  LDD0462 
Integrator complex subunit 7 (INTS7) LDTP12678 .  LDD0462 
Integrin beta-4 (ITGB4) LDTP02829 .  LDD0462 
Inverted formin-2 (INF2) LDTP06681 .; .  LDD0462 
Keratin, type II cuticular Hb1 (KRT81) LDTP06141 .; .; .  LDD0462 
Keratin, type II cytoskeletal 7 (KRT7) LDTP02305 .  LDD0462 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 .  LDD0462 
Large proline-rich protein BAG6 (BAG6) LDTP04094 .  LDD0462 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 .  LDD0462 
Large ribosomal subunit protein P1 (RPLP1) LDTP02107 .  LDD0462 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 .  LDD0462 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 .  LDD0462 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 .  LDD0462 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 .  LDD0462 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 .; .  LDD0462 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 .  LDD0462 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 .; .  LDD0462 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 .  LDD0462 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 .; .  LDD0462 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 .  LDD0462 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 .; .; . ...  LDD0462 
Lipase maturation factor 2 (LMF2) LDTP15887 .  LDD0462 
Luc7-like protein 3 (LUC7L3) LDTP01534 .  LDD0462 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 .  LDD0462 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 .  LDD0462 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 .  LDD0462 
Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 .  LDD0462 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 .  LDD0462 
MTOR-associated protein MEAK7 (MEAK7) LDTP07550 .  LDD0462 
Myb-binding protein 1A (MYBBP1A) LDTP11079 .; .; . ...  LDD0462 
NADH dehydrogenase 1 alpha subcomplex assembly factor 4 (NDUFAF4) LDTP12953 .  LDD0462 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 .; .  LDD0462 
Neutrophil gelatinase-associated lipocalin (LCN2) LDTP05156 .  LDD0462 
Nuclear migration protein nudC (NUDC) LDTP13817 .  LDD0462 
Nucleolar protein 56 (NOP56) LDTP00313 .; .  LDD0462 
OCIA domain-containing protein 2 (OCIAD2) LDTP17157 .; .  LDD0462 
Oxysterol-binding protein-related protein 3 (OSBPL3) LDTP11930 .  LDD0462 
Pentatricopeptide repeat-containing protein 1, mitochondrial (PTCD1) LDTP01130 .  LDD0462 
Perilipin-3 (PLIN3) LDTP01021 .; .  LDD0462 
Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1IP) LDTP04586 .  LDD0462 
Plastin-2 (LCP1) LDTP02691 .  LDD0462 
Plastin-3 (PLS3) LDTP02692 .  LDD0462 
Plectin (PLEC) LDTP06330 .; .  LDD0462 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 .; .  LDD0462 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 .  LDD0462 
Pre-rRNA-processing protein TSR2 homolog (TSR2) LDTP09989 .  LDD0462 
Proliferating cell nuclear antigen (PCNA) LDTP02596 .; .  LDD0462 
Proline-rich protein 11 (PRR11) LDTP15734 .  LDD0462 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 .; .  LDD0462 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 .  LDD0462 
Protein C10 (C12orf57) LDTP10923 .  LDD0462 
Protein FAM136A (FAM136A) LDTP18132 .  LDD0462 
Protein FAM210B, mitochondrial (FAM210B) LDTP10519 .  LDD0462 
Protein Hook homolog 1 (HOOK1) LDTP13383 .  LDD0462 
Protein odr-4 homolog (ODR4) LDTP17214 .  LDD0462 
Protein phosphatase 1 regulatory subunit 21 (PPP1R21) LDTP07768 .  LDD0462 
Protein S100-A11 (S100A11) LDTP03620 .; .  LDD0462 
Protein S100-A14 (S100A14) LDTP12277 .; .  LDD0462 
Protein SAAL1 (SAAL1) LDTP18152 .  LDD0462 
Protein ZNRD2 (ZNRD2) LDTP00916 .  LDD0462 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 .  LDD0462 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 .  LDD0462 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 .; .  LDD0462 
Reticulon-4 (RTN4) LDTP12412 .  LDD0462 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 .  LDD0462 
Ribonuclease inhibitor (RNH1) LDTP02656 .  LDD0462 
RRP12-like protein (RRP12) LDTP14980 .  LDD0462 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 .  LDD0462 
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3) LDTP06983 .  LDD0462 
Serpin B5 (SERPINB5) LDTP03825 .  LDD0462 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 .; .  LDD0462 
SLAIN motif-containing protein 2 (SLAIN2) LDTP13023 .  LDD0462 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 .  LDD0462 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 .; .; . ...  LDD0462 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 .  LDD0462 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 .  LDD0462 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 .  LDD0462 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 .  LDD0462 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 .  LDD0462 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 .; .  LDD0462 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 .; .; .  LDD0462 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 .  LDD0462 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 .; .  LDD0462 
Splicing factor 3A subunit 1 (SF3A1) LDTP06393 .  LDD0462 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 .  LDD0462 
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) LDTP06280 .  LDD0462 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 .; .; . ...  LDD0462 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 .  LDD0462 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 .  LDD0462 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 .; .  LDD0462 
T-complex protein 1 subunit eta (CCT7) LDTP10990 .; .  LDD0462 
T-complex protein 1 subunit theta (CCT8) LDTP04390 .; .  LDD0462 
Telomere-associated protein RIF1 (RIF1) LDTP07205 .  LDD0462 
Tetraspanin-31 (TSPAN31) LDTP14827 .  LDD0462 
Transgelin-2 (TAGLN2) LDTP03846 .; .; .  LDD0462 
Translationally-controlled tumor protein (TPT1) LDTP02683 .  LDD0462 
Transmembrane protein 248 (TMEM248) LDTP12712 .  LDD0462 
Tubulin beta 8B (TUBB8B) LDTP00119 .; .  LDD0462 
Tubulin beta chain (TUBB) LDTP02205 .; .; .  LDD0462 
Tubulin beta-2A chain (TUBB2A) LDTP05998 .; .; . ...  LDD0462 
Tubulin beta-3 chain (TUBB3) LDTP05904 .; .  LDD0462 
Tubulin beta-4B chain (TUBB4B) LDTP05076 .; .; . ...  LDD0462 
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) LDTP05033 .  LDD0462 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 .  LDD0462 
Vesicle transport protein SFT2C (SFT2D3) LDTP19324 .  LDD0462 
Vinculin (VCL) LDTP02946 .  LDD0462 
Zinc finger protein-like 1 (ZFPL1) LDTP01510 .  LDD0462 
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⏷ Show the Full List of 166 Other

Full Information of The Labelling Profiles of This Competitor

JZ128-DTB
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 2 uM
Quantitative Method iTRAQ
Competitor Name JZ128
Competitor Concentration 5 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Prostate
Disease Model Prostate carcinoma [ICD-11:2C82]
Model Name Human prostate carcinoma cell lysate (PC-3)
Interaction Atlas ID  LDD0462  Download The Altas

References

1 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.