Details of the Target

General Information of Target

Target ID LDTP05597
Target Name Neuroblast differentiation-associated protein AHNAK (AHNAK)
Gene Name AHNAK
Gene ID 79026
Synonyms
PM227; Neuroblast differentiation-associated protein AHNAK; Desmoyokin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI
YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE
YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF
KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG
HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGD
HGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPS
ANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDI
DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE
GKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSR
VDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKV
PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISIS
GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVP
KLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDI
SGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTM
PKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN
LPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKV
KGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDV
NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPK
MKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK
GEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDV
DLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP
KFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA
PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHL
KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFK
MPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVE
VHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEG
KLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKM
DVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEG
EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD
IDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEID
ASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDV
DLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAP
KISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP
EMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVH
GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKL
KGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVEL
ECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDI
RGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVD
VEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGE
LKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKA
KGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDL
NLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM
PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKIS
MPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPK
VKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEM
NIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGP
DWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKS
PKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDV
PDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIE
GPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR
GPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI
DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM
KVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLD
VSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVS
LANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDL
NLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFS
GSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV
ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMP
KFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKA
PKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHL
KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFK
MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDIN
IEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVD
IKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV
DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG
DMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKAD
LDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVD
VSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEV
DVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKG
PKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPG
FKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP
DFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK
MPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNI
KAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEG
KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEG
KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV
GIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEG
DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD
IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD
VTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV
DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG
PKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPD
VDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKF
GFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQ
GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSP
KFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLK
GPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP
DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSL
KGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV
GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGS
IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK
VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISG
PEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPD
ISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL
SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW
EESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAE
ASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKL
KFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPE
VELSVSTKKE
Target Bioclass
Other
Subcellular location
Nucleus
Function May be required for neuronal cell differentiation.
Uniprot ID
Q09666
Ensemble ID
ENST00000257247.11
HGNC ID
HGNC:347
ChEMBL ID
CHEMBL4296008

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AGS SNV: p.K1509T; p.L2288R; p.K2619N DBIA    Probe Info 
AN3CA Deletion: p.M3022CfsTer4
SNV: p.G3437C		 DBIA    Probe Info 
C4II SNV: p.K3782E DBIA    Probe Info 
CAL120 SNV: p.K1711I DBIA    Probe Info 
CCK81 SNV: p.A2229V DBIA    Probe Info 
CHL1 SNV: p.D1071N; p.D2552N DBIA    Probe Info 
DAOY SNV: p.L4832R DBIA    Probe Info 
DOTC24510 SNV: p.V112M; p.G3524V DBIA    Probe Info 
DU145 SNV: p.G3162D; p.G3925V; p.G5568R DBIA    Probe Info 
ECC2 SNV: p.L3433V
Substitution: p.D3434N		 DBIA    Probe Info 
HCC1419 SNV: p.D2540H DBIA    Probe Info 
HCC15 SNV: p.G1882Ter DBIA    Probe Info 
HCC1806 SNV: p.Q403H DBIA    Probe Info 
HCC827 SNV: p.S4220L DBIA    Probe Info 
HCT116 SNV: p.P2905H DBIA    Probe Info 
HCT15 SNV: p.H187Y; p.G2745C; p.A5761T DBIA    Probe Info 
HEC1 SNV: p.P4712H DBIA    Probe Info 
HEC1B SNV: p.D2803G; p.P3461L; p.I4361V; p.P4712H IA-alkyne    Probe Info 
HS936T SNV: p.P4852L DBIA    Probe Info 
HT SNV: p.D2552A .
HT115 SNV: p.P1894S; p.A2450S; p.F3610C; p.D4097G DBIA    Probe Info 
HUH28 SNV: p.P5645R DBIA    Probe Info 
IM95 SNV: p.R556G DBIA    Probe Info 
Ishikawa (Heraklio) 02 ER SNV: p.S295P DBIA    Probe Info 
J82 SNV: p.I5196V DBIA    Probe Info 
JHH6 SNV: p.K2896R DBIA    Probe Info 
JURKAT SNV: p.S357T .
K562 SNV: p.A399G .
KELLY SNV: p.G5487D
Substitution: p.S1876K		 .
KPNYN SNV: p.I4233T .
KYSE150 SNV: p.K4659M DBIA    Probe Info 
KYSE30 SNV: p.D1121H; p.D3651Y DBIA    Probe Info 
KYSE510 SNV: p.D5439N DBIA    Probe Info 
L428 SNV: p.G22R DBIA    Probe Info 
LN18 SNV: p.D1028E DBIA    Probe Info 
LNCaP clone FGC SNV: p.L854I; p.G2685R; p.G5359E DBIA    Probe Info 
LS123 SNV: p.P1925T DBIA    Probe Info 
LS180 Insertion: p.Q5040TfsTer4
SNV: p.M1131I;p.A2752T;p.V5461A		 DBIA    Probe Info 
MCC13 SNV: p.P816S DBIA    Probe Info 
MCC26 Substitution: p.P5001F DBIA    Probe Info 
MEWO SNV: p.S5720F
Substitution: p.G1938K		 DBIA    Probe Info 
MFE319 SNV: p.D421N; p.I3134V; p.K4979E DBIA    Probe Info 
MOLT4 SNV: p.G2799E .
MSTO211H SNV: p.P2966L DBIA    Probe Info 
NALM6 SNV: p.D4808E; p.G5594R DBIA    Probe Info 
NCIH1048 Deletion: p.M1515CfsTer18 DBIA    Probe Info 
NCIH1944 SNV: p.P3332L DBIA    Probe Info 
NCIH2052 SNV: p.P2409S DBIA    Probe Info 
NCIH2172 SNV: p.G586C DBIA    Probe Info 
NCIH446 SNV: p.G2027V; p.K2731E .
OAW28 SNV: p.D1340V DBIA    Probe Info 
OZ SNV: p.P700L DBIA    Probe Info 
PC3 SNV: p.K1649R JZ128-DTB    Probe Info 
PC9 SNV: p.D611N .
PEO1 SNV: p.D1377N DBIA    Probe Info 
RT112 SNV: p.D2796Y DBIA    Probe Info 
SHP77 SNV: p.I3322M DBIA    Probe Info 
SISO SNV: p.M3685T DBIA    Probe Info 
SKMEL2 SNV: p.H1459Y .
SKMM2 SNV: p.K263E DBIA    Probe Info 
SNU1196 SNV: p.K1738E DBIA    Probe Info 
SW1573 SNV: p.D4391E DBIA    Probe Info 
TCCSUP SNV: p.E95D DBIA    Probe Info 
TE1 SNV: p.V2755I DBIA    Probe Info 
TE10 Insertion: p.M4595IfsTer3 DBIA    Probe Info 
TE4 SNV: p.D2414E DBIA    Probe Info 
U937 SNV: p.E795V .
UMUC3 SNV: p.S3347Ter .
WM793 SNV: p.L236F DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 39 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
P2
 Probe Info  		3.02  LDD0449  [1]
P3
 Probe Info  		2.59  LDD0450  [1]
P8
 Probe Info  		3.63  LDD0451  [1]
AZ-9
 Probe Info  		2.04  LDD0393  [2]
CY-1
 Probe Info  		100.00  LDD0243  [3]
CY4
 Probe Info  		100.00  LDD0244  [3]
N1
 Probe Info  		100.00  LDD0242  [3]
C-Sul
 Probe Info  		3.31  LDD0066  [4]
ONAyne
 Probe Info  		K1125(1.82); K128(0.66); K134(5.00); K1488(8.80)  LDD0274  [5]
STPyne
 Probe Info  		K1012(6.25); K1049(3.60); K1056(7.70); K1066(4.37)  LDD0277  [5]
BTD
 Probe Info  		C2806(5.96)  LDD1699  [6]
OPA-S-S-alkyne
 Probe Info  		K313(0.25); K5443(0.97); K2993(1.00); K130(1.37)  LDD3494  [7]
Probe 1
 Probe Info  		Y160(9.66); Y5836(14.17)  LDD3495  [8]
JZ128-DTB
 Probe Info  		C2806(0.00); C108(0.00)  LDD0462  [9]
AHL-Pu-1
 Probe Info  		C1900(6.64); C5502(2.28)  LDD0168  [10]
EA-probe
 Probe Info  		N.A.  LDD0440  [11]
DBIA
 Probe Info  		C108(1.06); C2806(1.02); C5502(0.97); C1833(0.95)  LDD0078  [12]
5E-2FA
 Probe Info  		H241(0.00); H301(0.00); H21(0.00); H5618(0.00)  LDD2235  [13]
ATP probe
 Probe Info  		K582(0.00); K584(0.00)  LDD0199  [14]
ATP probe
 Probe Info  		K2765, K4059, K4315, K2242, K748(0.00); K1319, K1851, K1649, K2113(0.00); K4187, K4651(0.00)  LDD0035  [15]
IPM
 Probe Info  		C1900(0.00); C5382(0.00); C2806(0.00); C5502(0.00)  LDD0025  [16]
JW-RF-010
 Probe Info  		C1900, C1967(0.00); C2806(0.00); C5382(0.00); C1833(0.00)  LDD0026  [16]
NAIA_4
 Probe Info  		C567(0.00); C1833(0.00); C1900(0.00); C2162(0.00)  LDD2226  [17]
NAIA_5
 Probe Info  		C2806(0.00); C108(0.00); C1833(0.00); C1900(0.00)  LDD2224  [17]
TFBX
 Probe Info  		C108(0.00); C5502(0.00); C1833(0.00); C2162(0.00)  LDD0027  [16]
WYneN
 Probe Info  		C1967, C1900(0.00); C5502(0.00); C2162(0.00); C1833(0.00)  LDD0021  [18]
WYneO
 Probe Info  		C1833(0.00); C1967, C1900(0.00); C2806(0.00); C5502(0.00)  LDD0022  [18]
ENE
 Probe Info  		N.A.  LDD0006  [18]
IA-alkyne
 Probe Info  		C1833(0.00); C1900(0.00); C2162(0.00)  LDD0149  [19]
VSF
 Probe Info  		C2806(0.00); C1833(0.00); C1900, C1967(0.00)  LDD0007  [18]
Phosphinate-6
 Probe Info  		C567(0.00); C1833(0.00); C5502(0.00); C5382(0.00)  LDD0018  [20]
Acrolein
 Probe Info  		H5835(0.00); H4313(0.00); C1967(0.00); C1833(0.00)  LDD0217  [21]
Crotonaldehyde
 Probe Info  		H5535(0.00); C5502(0.00); C2806(0.00)  LDD0219  [21]
Methacrolein
 Probe Info  		C1833(0.00); C5502(0.00); C2806(0.00); C1967(0.00)  LDD0218  [21]
W1
 Probe Info  		C2806(0.00); C5502(0.00); C1833(0.00); D1419(0.00)  LDD0236  [22]
m-APA
 Probe Info  		C108(0.00); C5502(0.00); C2162(0.00); C1833(0.00)  LDD0404  [23]
HHS-465
 Probe Info  		Y1469(0.00); K805(0.00); Y160(0.00)  LDD2240  [24]
HHS-475
 Probe Info  		Y1469(1.00)  LDD2238  [25]
HHS-482
 Probe Info  		Y1469(1.21); Y715(1.11); Y836(0.77)  LDD2239  [25]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info  		N.A.  LDD0396  [26]
DA-2
 Probe Info  		N.A.  LDD0072  [27]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C2806(0.94); C5502(0.76); C1833(0.38); C1967(0.99)  LDD2142  [6]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C2806(0.78); C1833(0.68); C1967(0.94); C1900(0.94)  LDD2112  [6]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C2806(0.70); C5502(0.56); C1833(0.54); C1967(0.53)  LDD2095  [6]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C5502(1.01); C1833(1.01); C5382(0.85); C2162(1.02)  LDD2130  [6]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C2806(0.99); C5502(0.94); C1833(0.88)  LDD2117  [6]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C5502(1.13); C5382(0.90)  LDD2152  [6]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C5502(1.00); C5382(0.90)  LDD2103  [6]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C2806(0.73); C5502(0.40); C1833(0.54); C1967(0.49)  LDD2132  [6]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C5502(0.60); C1833(0.99); C1967(0.89); C1900(0.89)  LDD2131  [6]
 LDCM0025  4SU-RNA HEK-293T C1900(6.64); C5502(2.28)  LDD0168  [10]
 LDCM0026  4SU-RNA+native RNA HEK-293T C1900(4.43)  LDD0169  [10]
 LDCM0214  AC1 HCT 116 C108(1.15); C5502(1.07)  LDD0531  [12]
 LDCM0215  AC10 HCT 116 C108(1.06); C2806(1.01); C5502(0.84)  LDD0532  [12]
 LDCM0216  AC100 HCT 116 C108(0.97); C5502(1.06)  LDD0533  [12]
 LDCM0217  AC101 HCT 116 C108(0.94); C5502(1.07)  LDD0534  [12]
 LDCM0218  AC102 HCT 116 C108(0.94); C5502(1.04)  LDD0535  [12]
 LDCM0219  AC103 HCT 116 C108(1.25); C5502(1.23)  LDD0536  [12]
 LDCM0220  AC104 HCT 116 C108(1.12); C5502(1.06)  LDD0537  [12]
 LDCM0221  AC105 HCT 116 C108(1.12); C5502(1.18)  LDD0538  [12]
 LDCM0222  AC106 HCT 116 C108(1.20); C5502(1.27)  LDD0539  [12]
 LDCM0223  AC107 HCT 116 C108(1.11); C5502(1.10)  LDD0540  [12]
 LDCM0224  AC108 HCT 116 C108(1.08); C5502(0.97)  LDD0541  [12]
 LDCM0225  AC109 HCT 116 C108(1.07); C5502(0.88)  LDD0542  [12]
 LDCM0226  AC11 HCT 116 C108(1.20); C2806(1.12); C5502(0.95)  LDD0543  [12]
 LDCM0227  AC110 HCT 116 C108(1.12); C5502(0.99)  LDD0544  [12]
 LDCM0228  AC111 HCT 116 C108(1.23); C5502(1.01)  LDD0545  [12]
 LDCM0229  AC112 HCT 116 C108(0.98); C5502(1.15)  LDD0546  [12]
 LDCM0230  AC113 HCT 116 C108(1.03); C1900(0.91); C5502(0.64)  LDD0547  [12]
 LDCM0231  AC114 HCT 116 C108(1.16); C1900(1.23); C5502(0.83)  LDD0548  [12]
 LDCM0232  AC115 HCT 116 C108(1.23); C1900(1.23); C5502(0.83)  LDD0549  [12]
 LDCM0233  AC116 HCT 116 C108(1.49); C1900(1.30); C5502(0.94)  LDD0550  [12]
 LDCM0234  AC117 HCT 116 C108(1.13); C1900(1.03); C5502(1.00)  LDD0551  [12]
 LDCM0235  AC118 HCT 116 C108(1.04); C1900(1.34); C5502(0.79)  LDD0552  [12]
 LDCM0236  AC119 HCT 116 C108(1.31); C1900(1.17); C5502(0.84)  LDD0553  [12]
 LDCM0237  AC12 HCT 116 C108(0.94); C2806(1.09); C5502(0.88)  LDD0554  [12]
 LDCM0238  AC120 HCT 116 C108(1.07); C1900(0.87); C5502(1.03)  LDD0555  [12]
 LDCM0239  AC121 HCT 116 C108(0.92); C1900(1.07); C5502(0.84)  LDD0556  [12]
 LDCM0240  AC122 HCT 116 C108(1.05); C1900(1.04); C5502(0.66)  LDD0557  [12]
 LDCM0241  AC123 HCT 116 C108(0.99); C1900(0.86); C5502(0.77)  LDD0558  [12]
 LDCM0242  AC124 HCT 116 C108(1.14); C1900(0.90); C5502(0.83)  LDD0559  [12]
 LDCM0243  AC125 HCT 116 C108(1.00); C1900(1.24); C5502(0.71)  LDD0560  [12]
 LDCM0244  AC126 HCT 116 C108(1.25); C1900(1.28); C5502(0.83)  LDD0561  [12]
 LDCM0245  AC127 HCT 116 C108(1.17); C1900(1.23); C5502(0.87)  LDD0562  [12]
 LDCM0246  AC128 HCT 116 C108(1.46); C1900(1.49); C5502(0.64)  LDD0563  [12]
 LDCM0247  AC129 HCT 116 C108(0.87); C1900(1.26); C5502(0.73)  LDD0564  [12]
 LDCM0249  AC130 HCT 116 C108(1.50); C1900(1.39); C5502(0.80)  LDD0566  [12]
 LDCM0250  AC131 HCT 116 C108(1.28); C1900(1.36); C5502(0.77)  LDD0567  [12]
 LDCM0251  AC132 HCT 116 C108(0.71); C1900(1.25); C5502(0.92)  LDD0568  [12]
 LDCM0252  AC133 HCT 116 C108(0.77); C1900(1.62); C5502(0.75)  LDD0569  [12]
 LDCM0253  AC134 HCT 116 C108(1.00); C1900(1.68); C5502(1.03)  LDD0570  [12]
 LDCM0254  AC135 HCT 116 C108(1.00); C1900(1.55); C5502(0.84)  LDD0571  [12]
 LDCM0255  AC136 HCT 116 C108(1.04); C1900(1.08); C5502(0.95)  LDD0572  [12]
 LDCM0256  AC137 HCT 116 C108(0.97); C1900(1.10); C5502(0.99)  LDD0573  [12]
 LDCM0257  AC138 HCT 116 C108(0.83); C1900(1.69); C5502(1.19)  LDD0574  [12]
 LDCM0258  AC139 HCT 116 C108(0.79); C1900(1.32); C5502(1.06)  LDD0575  [12]
 LDCM0259  AC14 HCT 116 C108(1.04); C2806(0.87); C5502(0.77)  LDD0576  [12]
 LDCM0260  AC140 HCT 116 C108(1.00); C1900(1.52); C5502(1.39)  LDD0577  [12]
 LDCM0261  AC141 HCT 116 C108(0.91); C1900(1.36); C5502(1.24)  LDD0578  [12]
 LDCM0262  AC142 HCT 116 C108(0.78); C1900(1.12); C5502(0.97)  LDD0579  [12]
 LDCM0263  AC143 HCT 116 C108(1.20); C1900(1.48); C2806(1.04); C5502(1.09)  LDD0580  [12]
 LDCM0264  AC144 HCT 116 C5502(1.00); C2806(1.04); C1900(1.57); C108(1.76)  LDD0581  [12]
 LDCM0265  AC145 HCT 116 C1900(1.00); C2806(1.09); C5502(1.11); C108(1.15)  LDD0582  [12]
 LDCM0266  AC146 HCT 116 C2806(0.96); C5502(0.96); C108(1.14); C1900(1.61)  LDD0583  [12]
 LDCM0267  AC147 HCT 116 C5502(0.97); C2806(1.10); C1900(1.23); C108(1.46)  LDD0584  [12]
 LDCM0268  AC148 HCT 116 C5502(0.95); C2806(1.48); C1900(1.51); C108(1.89)  LDD0585  [12]
 LDCM0269  AC149 HCT 116 C5502(1.17); C2806(1.27); C1900(1.54); C108(1.74)  LDD0586  [12]
 LDCM0270  AC15 HCT 116 C5502(0.75); C2806(0.98); C108(1.12)  LDD0587  [12]
 LDCM0271  AC150 HCT 116 C2806(0.94); C5502(0.96); C1900(0.97); C108(1.10)  LDD0588  [12]
 LDCM0272  AC151 HCT 116 C1900(0.91); C2806(0.95); C5502(0.97); C108(1.20)  LDD0589  [12]
 LDCM0273  AC152 HCT 116 C5502(0.99); C2806(1.01); C1900(1.21); C108(1.77)  LDD0590  [12]
 LDCM0274  AC153 HCT 116 C5502(1.29); C2806(1.56); C108(2.04); C1900(2.78)  LDD0591  [12]
 LDCM0621  AC154 HCT 116 C108(1.16); C1900(1.35); C2806(1.16); C5502(0.93)  LDD2158  [12]
 LDCM0622  AC155 HCT 116 C108(1.76); C1900(1.32); C2806(1.06); C5502(0.97)  LDD2159  [12]
 LDCM0623  AC156 HCT 116 C108(1.35); C1900(1.15); C2806(0.87); C5502(0.97)  LDD2160  [12]
 LDCM0624  AC157 HCT 116 C108(1.04); C1900(1.10); C2806(0.99); C5502(0.99)  LDD2161  [12]
 LDCM0276  AC17 HCT 116 C5502(0.99); C108(1.04)  LDD0593  [12]
 LDCM0277  AC18 HCT 116 C108(1.02); C5502(1.30)  LDD0594  [12]
 LDCM0278  AC19 HCT 116 C5502(1.05); C108(1.48)  LDD0595  [12]
 LDCM0279  AC2 HCT 116 C5502(1.04); C108(1.23)  LDD0596  [12]
 LDCM0280  AC20 HCT 116 C108(1.02); C5502(1.20)  LDD0597  [12]
 LDCM0281  AC21 HCT 116 C5502(1.09); C108(1.16)  LDD0598  [12]
 LDCM0282  AC22 HCT 116 C108(0.92); C5502(0.99)  LDD0599  [12]
 LDCM0283  AC23 HCT 116 C5502(0.92); C108(1.13)  LDD0600  [12]
 LDCM0284  AC24 HCT 116 C5502(0.87); C108(1.11)  LDD0601  [12]
 LDCM0285  AC25 HCT 116 C2806(0.86); C5502(1.01); C108(1.09)  LDD0602  [12]
 LDCM0286  AC26 HCT 116 C2806(1.04); C5502(1.31); C108(1.34)  LDD0603  [12]
 LDCM0287  AC27 HCT 116 C2806(1.15); C5502(1.17); C108(1.49)  LDD0604  [12]
 LDCM0288  AC28 HCT 116 C2806(1.13); C5502(1.37); C108(1.39)  LDD0605  [12]
 LDCM0289  AC29 HCT 116 C108(1.25); C2806(1.27); C5502(1.49)  LDD0606  [12]
 LDCM0290  AC3 HCT 116 C5502(0.95); C108(1.13)  LDD0607  [12]
 LDCM0291  AC30 HCT 116 C2806(1.26); C108(1.36); C5502(1.40)  LDD0608  [12]
 LDCM0292  AC31 HCT 116 C2806(1.12); C108(1.25); C5502(1.29)  LDD0609  [12]
 LDCM0293  AC32 HCT 116 C2806(1.35); C5502(1.55); C108(1.62)  LDD0610  [12]
 LDCM0294  AC33 HCT 116 C2806(1.02); C5502(1.26); C108(1.39)  LDD0611  [12]
 LDCM0295  AC34 HCT 116 C2806(1.06); C5502(1.48); C108(1.73)  LDD0612  [12]
 LDCM0296  AC35 HCT 116 C2806(0.73); C108(0.89); C5502(0.91)  LDD0613  [12]
 LDCM0297  AC36 HCT 116 C5502(0.88); C108(0.93); C2806(0.94)  LDD0614  [12]
 LDCM0298  AC37 HCT 116 C2806(0.66); C108(0.93); C5502(0.99)  LDD0615  [12]
 LDCM0299  AC38 HCT 116 C2806(0.98); C5502(1.02); C108(1.06)  LDD0616  [12]
 LDCM0300  AC39 HCT 116 C2806(0.82); C108(1.01); C5502(1.25)  LDD0617  [12]
 LDCM0301  AC4 HCT 116 C5502(1.07); C108(1.21)  LDD0618  [12]
 LDCM0302  AC40 HCT 116 C2806(0.58); C5502(1.09); C108(1.24)  LDD0619  [12]
 LDCM0303  AC41 HCT 116 C2806(0.91); C5502(1.04); C108(1.08)  LDD0620  [12]
 LDCM0304  AC42 HCT 116 C2806(0.94); C108(1.16); C5502(1.17)  LDD0621  [12]
 LDCM0305  AC43 HCT 116 C5502(1.20); C108(1.24); C2806(1.30)  LDD0622  [12]
 LDCM0306  AC44 HCT 116 C2806(0.71); C5502(1.08); C108(1.08)  LDD0623  [12]
 LDCM0307  AC45 HCT 116 C2806(0.67); C108(1.19); C5502(1.27)  LDD0624  [12]
 LDCM0308  AC46 HCT 116 C5502(1.08); C108(1.18)  LDD0625  [12]
 LDCM0309  AC47 HCT 116 C5502(0.93); C108(1.12)  LDD0626  [12]
 LDCM0310  AC48 HCT 116 C108(1.10); C5502(1.15)  LDD0627  [12]
 LDCM0311  AC49 HCT 116 C108(1.41); C5502(1.63)  LDD0628  [12]
 LDCM0312  AC5 HCT 116 C5502(1.10); C108(1.29)  LDD0629  [12]
 LDCM0313  AC50 HCT 116 C108(1.33); C5502(1.34)  LDD0630  [12]
 LDCM0314  AC51 HCT 116 C5502(0.86); C108(0.96)  LDD0631  [12]
 LDCM0315  AC52 HCT 116 C108(1.05); C5502(1.13)  LDD0632  [12]
 LDCM0316  AC53 HCT 116 C5502(1.30); C108(1.33)  LDD0633  [12]
 LDCM0317  AC54 HCT 116 C108(1.22); C5502(1.36)  LDD0634  [12]
 LDCM0318  AC55 HCT 116 C108(1.38); C5502(1.64)  LDD0635  [12]
 LDCM0319  AC56 HCT 116 C108(1.77); C5502(2.12)  LDD0636  [12]
 LDCM0320  AC57 HCT 116 C5502(0.85); C108(1.57)  LDD0637  [12]
 LDCM0321  AC58 HCT 116 C5502(0.97); C108(1.41)  LDD0638  [12]
 LDCM0322  AC59 HCT 116 C5502(0.81); C108(1.38)  LDD0639  [12]
 LDCM0323  AC6 HCT 116 C2806(1.02); C5502(1.08); C108(1.13)  LDD0640  [12]
 LDCM0324  AC60 HCT 116 C5502(0.86); C108(1.19)  LDD0641  [12]
 LDCM0325  AC61 HCT 116 C5502(0.98); C108(1.14)  LDD0642  [12]
 LDCM0326  AC62 HCT 116 C5502(0.75); C108(1.51)  LDD0643  [12]
 LDCM0327  AC63 HCT 116 C5502(0.70); C108(1.42)  LDD0644  [12]
 LDCM0328  AC64 HCT 116 C5502(0.73); C108(1.32)  LDD0645  [12]
 LDCM0329  AC65 HCT 116 C108(0.88); C5502(1.11)  LDD0646  [12]
 LDCM0330  AC66 HCT 116 C108(0.86); C5502(0.93)  LDD0647  [12]
 LDCM0331  AC67 HCT 116 C5502(0.85); C108(0.97)  LDD0648  [12]
 LDCM0332  AC68 HCT 116 C108(0.92); C5502(1.31)  LDD0649  [12]
 LDCM0333  AC69 HCT 116 C108(1.04); C5502(1.19)  LDD0650  [12]
 LDCM0334  AC7 HCT 116 C5502(0.94); C2806(0.95); C108(0.95)  LDD0651  [12]
 LDCM0335  AC70 HCT 116 C108(1.01); C5502(1.29)  LDD0652  [12]
 LDCM0336  AC71 HCT 116 C108(0.82); C5502(1.01)  LDD0653  [12]
 LDCM0337  AC72 HCT 116 C108(1.22); C5502(1.27)  LDD0654  [12]
 LDCM0338  AC73 HCT 116 C108(1.50); C5502(1.60)  LDD0655  [12]
 LDCM0339  AC74 HCT 116 C108(1.31); C5502(1.44)  LDD0656  [12]
 LDCM0340  AC75 HCT 116 C108(1.66); C5502(1.73)  LDD0657  [12]
 LDCM0341  AC76 HCT 116 C108(1.10); C5502(1.19)  LDD0658  [12]
 LDCM0342  AC77 HCT 116 C108(1.16); C5502(1.38)  LDD0659  [12]
 LDCM0343  AC78 HCT 116 C108(0.96); C5502(1.16)  LDD0660  [12]
 LDCM0344  AC79 HCT 116 C108(1.03); C5502(1.17)  LDD0661  [12]
 LDCM0345  AC8 HCT 116 C5502(1.05); C108(1.06); C2806(1.09)  LDD0662  [12]
 LDCM0346  AC80 HCT 116 C5502(1.10); C108(1.16)  LDD0663  [12]
 LDCM0347  AC81 HCT 116 C108(1.04); C5502(1.14)  LDD0664  [12]
 LDCM0348  AC82 HCT 116 C5502(1.58); C108(1.69)  LDD0665  [12]
 LDCM0349  AC83 HCT 116 C5502(1.29); C108(1.67); C1900(1.90)  LDD0666  [12]
 LDCM0350  AC84 HCT 116 C5502(1.26); C1900(1.40); C108(1.51)  LDD0667  [12]
 LDCM0351  AC85 HCT 116 C1900(1.17); C108(1.23); C5502(1.36)  LDD0668  [12]
 LDCM0352  AC86 HCT 116 C108(1.27); C5502(1.31); C1900(1.61)  LDD0669  [12]
 LDCM0353  AC87 HCT 116 C1900(1.14); C5502(1.20); C108(1.26)  LDD0670  [12]
 LDCM0354  AC88 HCT 116 C1900(1.24); C5502(1.31); C108(1.38)  LDD0671  [12]
 LDCM0355  AC89 HCT 116 C5502(1.25); C1900(1.40); C108(1.52)  LDD0672  [12]
 LDCM0357  AC90 HCT 116 C1900(0.81); C108(1.03); C5502(1.19)  LDD0674  [12]
 LDCM0358  AC91 HCT 116 C5502(1.17); C108(1.73); C1900(1.77)  LDD0675  [12]
 LDCM0359  AC92 HCT 116 C5502(1.24); C108(1.82); C1900(1.99)  LDD0676  [12]
 LDCM0360  AC93 HCT 116 C5502(1.14); C1900(1.22); C108(1.40)  LDD0677  [12]
 LDCM0361  AC94 HCT 116 C1900(0.94); C5502(1.19); C108(1.35)  LDD0678  [12]
 LDCM0362  AC95 HCT 116 C5502(1.25); C1900(1.35); C108(1.36)  LDD0679  [12]
 LDCM0363  AC96 HCT 116 C5502(1.14); C108(1.56); C1900(1.70)  LDD0680  [12]
 LDCM0364  AC97 HCT 116 C5502(1.34); C1900(1.43); C108(1.75)  LDD0681  [12]
 LDCM0365  AC98 HCT 116 C108(1.60); C5502(1.72)  LDD0682  [12]
 LDCM0366  AC99 HCT 116 C108(0.98); C5502(1.09)  LDD0683  [12]
 LDCM0545  Acetamide MDA-MB-231 C2806(0.50)  LDD2138  [6]
 LDCM0520  AKOS000195272 MDA-MB-231 C2806(0.85)  LDD2113  [6]
 LDCM0248  AKOS034007472 HCT 116 C108(1.03); C2806(1.21); C5502(0.83)  LDD0565  [12]
 LDCM0356  AKOS034007680 HCT 116 C5502(0.93); C108(0.98); C2806(1.11)  LDD0673  [12]
 LDCM0275  AKOS034007705 HCT 116 C5502(0.94); C2806(1.04); C108(1.71)  LDD0592  [12]
 LDCM0156  Aniline NCI-H1299 C108(0.00); C5502(0.00); C2162(0.00); C1833(0.00)  LDD0404  [23]
 LDCM0020  ARS-1620 HCC44 C108(1.06); C2806(1.02); C5502(0.97); C1833(0.95)  LDD0078  [12]
 LDCM0498  BS-3668 MDA-MB-231 C2806(0.90); C5502(0.53); C1833(0.86); C2162(1.15)  LDD2091  [6]
 LDCM0630  CCW28-3 231MFP C1900(1.62); C2162(1.53); C2806(1.35); C1833(1.32)  LDD2214  [28]
 LDCM0108  Chloroacetamide HeLa C1833(0.00); C1967(0.00); C5502(0.00); H4308(0.00)  LDD0222  [21]
 LDCM0632  CL-Sc Hep-G2 C1900(20.00); C1833(0.79)  LDD2227  [17]
 LDCM0367  CL1 HCT 116 C5502(1.09); C108(1.12); C2806(1.12)  LDD0684  [12]
 LDCM0368  CL10 HCT 116 C2806(0.97); C5502(1.03); C108(1.40)  LDD0685  [12]
 LDCM0369  CL100 HCT 116 C5502(1.13); C108(1.30)  LDD0686  [12]
 LDCM0370  CL101 HCT 116 C2806(0.60); C5502(0.84); C108(1.26)  LDD0687  [12]
 LDCM0371  CL102 HCT 116 C2806(0.53); C5502(0.77); C108(1.04)  LDD0688  [12]
 LDCM0372  CL103 HCT 116 C5502(0.75); C2806(0.75); C108(0.96)  LDD0689  [12]
 LDCM0373  CL104 HCT 116 C2806(0.82); C5502(0.82); C108(1.13)  LDD0690  [12]
 LDCM0374  CL105 HCT 116 C5502(1.11); C108(1.16)  LDD0691  [12]
 LDCM0375  CL106 HCT 116 C5502(1.19); C108(1.44)  LDD0692  [12]
 LDCM0376  CL107 HCT 116 C108(1.08); C5502(1.33)  LDD0693  [12]
 LDCM0377  CL108 HCT 116 C5502(1.30); C108(1.50)  LDD0694  [12]
 LDCM0378  CL109 HCT 116 C5502(1.12); C108(1.38)  LDD0695  [12]
 LDCM0379  CL11 HCT 116 C5502(0.98); C2806(1.01); C108(1.55)  LDD0696  [12]
 LDCM0380  CL110 HCT 116 C5502(1.24); C108(1.69)  LDD0697  [12]
 LDCM0381  CL111 HCT 116 C5502(1.19); C108(1.60)  LDD0698  [12]
 LDCM0382  CL112 HCT 116 C2806(0.90); C5502(1.07); C108(1.27)  LDD0699  [12]
 LDCM0383  CL113 HCT 116 C2806(1.06); C5502(1.41); C108(1.60)  LDD0700  [12]
 LDCM0384  CL114 HCT 116 C2806(1.06); C108(1.27); C5502(1.35)  LDD0701  [12]
 LDCM0385  CL115 HCT 116 C2806(1.19); C108(1.28); C5502(1.40)  LDD0702  [12]
 LDCM0386  CL116 HCT 116 C2806(0.92); C108(1.14); C5502(1.28)  LDD0703  [12]
 LDCM0387  CL117 HCT 116 C2806(0.90); C108(1.37); C5502(1.94)  LDD0704  [12]
 LDCM0388  CL118 HCT 116 C108(0.96); C2806(0.97); C5502(1.09)  LDD0705  [12]
 LDCM0389  CL119 HCT 116 C2806(1.04); C108(1.08); C5502(1.12)  LDD0706  [12]
 LDCM0390  CL12 HCT 116 C5502(1.02); C2806(1.11); C108(1.57)  LDD0707  [12]
 LDCM0391  CL120 HCT 116 C2806(1.00); C108(1.02); C5502(1.09)  LDD0708  [12]
 LDCM0392  CL121 HCT 116 C5502(1.20); C108(1.91)  LDD0709  [12]
 LDCM0393  CL122 HCT 116 C5502(1.02); C108(1.10)  LDD0710  [12]
 LDCM0394  CL123 HCT 116 C108(1.31); C5502(1.39)  LDD0711  [12]
 LDCM0395  CL124 HCT 116 C108(1.52); C5502(1.59)  LDD0712  [12]
 LDCM0396  CL125 HCT 116 C108(1.00); C5502(1.19)  LDD0713  [12]
 LDCM0397  CL126 HCT 116 C5502(1.11); C108(1.20)  LDD0714  [12]
 LDCM0398  CL127 HCT 116 C5502(1.00); C108(1.02)  LDD0715  [12]
 LDCM0399  CL128 HCT 116 C5502(0.98); C108(1.50)  LDD0716  [12]
 LDCM0400  CL13 HCT 116 C5502(0.90); C2806(1.08); C108(1.39)  LDD0717  [12]
 LDCM0401  CL14 HCT 116 C5502(0.91); C2806(1.08); C108(1.21)  LDD0718  [12]
 LDCM0402  CL15 HCT 116 C5502(0.88); C2806(1.16); C108(1.26)  LDD0719  [12]
 LDCM0403  CL16 HCT 116 C2806(1.05); C108(1.15)  LDD0720  [12]
 LDCM0404  CL17 HCT 116 C108(1.14); C5502(1.22)  LDD0721  [12]
 LDCM0405  CL18 HCT 116 C5502(1.13); C108(1.19)  LDD0722  [12]
 LDCM0406  CL19 HCT 116 C108(1.19); C5502(1.42)  LDD0723  [12]
 LDCM0407  CL2 HCT 116 C2806(0.97); C108(1.10); C5502(1.10)  LDD0724  [12]
 LDCM0408  CL20 HCT 116 C5502(1.22); C108(1.30)  LDD0725  [12]
 LDCM0409  CL21 HCT 116 C5502(1.03); C108(1.54)  LDD0726  [12]
 LDCM0410  CL22 HCT 116 C5502(1.11); C108(1.65)  LDD0727  [12]
 LDCM0411  CL23 HCT 116 C108(1.21); C5502(1.22)  LDD0728  [12]
 LDCM0412  CL24 HCT 116 C5502(1.19); C108(1.28)  LDD0729  [12]
 LDCM0413  CL25 HCT 116 C108(1.28); C5502(0.98)  LDD0730  [12]
 LDCM0414  CL26 HCT 116 C108(1.13); C5502(1.12)  LDD0731  [12]
 LDCM0415  CL27 HCT 116 C108(1.11); C5502(0.95)  LDD0732  [12]
 LDCM0416  CL28 HCT 116 C108(1.33); C5502(1.08)  LDD0733  [12]
 LDCM0417  CL29 HCT 116 C108(1.23); C5502(1.16)  LDD0734  [12]
 LDCM0418  CL3 HCT 116 C108(1.21); C2806(0.92); C5502(1.02)  LDD0735  [12]
 LDCM0419  CL30 HCT 116 C108(1.03); C5502(1.05)  LDD0736  [12]
 LDCM0420  CL31 HCT 116 C108(1.27); C1900(1.11); C2806(0.88); C5502(0.99)  LDD0737  [12]
 LDCM0421  CL32 HCT 116 C108(1.25); C1900(1.21); C2806(0.98); C5502(1.02)  LDD0738  [12]
 LDCM0422  CL33 HCT 116 C108(1.37); C1900(1.16); C2806(1.05); C5502(1.15)  LDD0739  [12]
 LDCM0423  CL34 HCT 116 C108(1.58); C1900(1.19); C2806(1.04); C5502(1.01)  LDD0740  [12]
 LDCM0424  CL35 HCT 116 C108(1.32); C1900(1.18); C2806(1.00); C5502(1.14)  LDD0741  [12]
 LDCM0425  CL36 HCT 116 C108(1.26); C1900(1.03); C2806(0.99); C5502(1.13)  LDD0742  [12]
 LDCM0426  CL37 HCT 116 C108(1.82); C1900(1.25); C2806(0.98); C5502(0.99)  LDD0743  [12]
 LDCM0428  CL39 HCT 116 C108(1.59); C1900(1.03); C2806(1.00); C5502(1.09)  LDD0745  [12]
 LDCM0429  CL4 HCT 116 C108(1.22); C2806(1.12); C5502(0.95)  LDD0746  [12]
 LDCM0430  CL40 HCT 116 C108(1.46); C1900(1.66); C2806(1.03); C5502(1.04)  LDD0747  [12]
 LDCM0431  CL41 HCT 116 C108(1.38); C1900(1.05); C2806(0.98); C5502(1.01)  LDD0748  [12]
 LDCM0432  CL42 HCT 116 C108(2.25); C1900(1.19); C2806(0.98); C5502(1.05)  LDD0749  [12]
 LDCM0433  CL43 HCT 116 C108(1.60); C1900(1.21); C2806(1.00); C5502(0.97)  LDD0750  [12]
 LDCM0434  CL44 HCT 116 C108(1.39); C1900(1.32); C2806(1.09); C5502(1.04)  LDD0751  [12]
 LDCM0435  CL45 HCT 116 C108(1.71); C1900(0.98); C2806(0.97); C5502(0.99)  LDD0752  [12]
 LDCM0436  CL46 HCT 116 C108(0.86); C2806(1.23); C5502(0.88)  LDD0753  [12]
 LDCM0437  CL47 HCT 116 C108(0.85); C2806(1.06); C5502(0.91)  LDD0754  [12]
 LDCM0438  CL48 HCT 116 C108(0.90); C2806(0.97); C5502(0.87)  LDD0755  [12]
 LDCM0439  CL49 HCT 116 C108(0.89); C2806(1.02); C5502(0.92)  LDD0756  [12]
 LDCM0440  CL5 HCT 116 C108(1.15); C2806(0.93); C5502(0.86)  LDD0757  [12]
 LDCM0441  CL50 HCT 116 C108(0.87); C2806(1.05); C5502(0.85)  LDD0758  [12]
 LDCM0442  CL51 HCT 116 C108(0.93); C2806(1.04); C5502(0.87)  LDD0759  [12]
 LDCM0443  CL52 HCT 116 C108(0.99); C2806(1.08); C5502(0.93)  LDD0760  [12]
 LDCM0444  CL53 HCT 116 C108(0.86); C2806(0.99); C5502(0.87)  LDD0761  [12]
 LDCM0445  CL54 HCT 116 C108(0.99); C2806(1.17); C5502(0.82)  LDD0762  [12]
 LDCM0446  CL55 HCT 116 C108(0.83); C2806(0.97); C5502(0.77)  LDD0763  [12]
 LDCM0447  CL56 HCT 116 C108(0.96); C2806(0.96); C5502(1.06)  LDD0764  [12]
 LDCM0448  CL57 HCT 116 C108(1.02); C2806(0.95); C5502(0.80)  LDD0765  [12]
 LDCM0449  CL58 HCT 116 C108(0.95); C2806(1.05); C5502(0.77)  LDD0766  [12]
 LDCM0450  CL59 HCT 116 C108(0.97); C2806(1.00); C5502(0.96)  LDD0767  [12]
 LDCM0451  CL6 HCT 116 C108(1.21); C2806(1.04); C5502(0.97)  LDD0768  [12]
 LDCM0452  CL60 HCT 116 C108(0.99); C2806(1.08); C5502(0.97)  LDD0769  [12]
 LDCM0453  CL61 HCT 116 C108(1.04); C1900(1.22); C2806(1.09); C5502(1.12)  LDD0770  [12]
 LDCM0454  CL62 HCT 116 C108(1.14); C1900(1.32); C2806(1.01); C5502(1.22)  LDD0771  [12]
 LDCM0455  CL63 HCT 116 C108(1.13); C1900(1.11); C2806(0.90); C5502(1.35)  LDD0772  [12]
 LDCM0456  CL64 HCT 116 C108(1.24); C1900(1.32); C2806(0.88); C5502(1.27)  LDD0773  [12]
 LDCM0457  CL65 HCT 116 C108(1.09); C1900(1.24); C2806(0.97); C5502(1.09)  LDD0774  [12]
 LDCM0458  CL66 HCT 116 C108(1.43); C1900(1.35); C2806(0.99); C5502(1.65)  LDD0775  [12]
 LDCM0459  CL67 HCT 116 C108(1.35); C1900(1.15); C2806(1.06); C5502(1.40)  LDD0776  [12]
 LDCM0460  CL68 HCT 116 C108(1.14); C1900(1.27); C2806(0.95); C5502(1.24)  LDD0777  [12]
 LDCM0461  CL69 HCT 116 C108(1.11); C1900(1.44); C2806(0.98); C5502(1.09)  LDD0778  [12]
 LDCM0462  CL7 HCT 116 C108(1.25); C2806(1.03); C5502(0.93)  LDD0779  [12]
 LDCM0463  CL70 HCT 116 C108(1.07); C1900(1.03); C2806(1.02); C5502(1.32)  LDD0780  [12]
 LDCM0464  CL71 HCT 116 C108(1.27); C1900(1.19); C2806(0.98); C5502(1.18)  LDD0781  [12]
 LDCM0465  CL72 HCT 116 C108(1.16); C1900(1.40); C2806(0.90); C5502(1.19)  LDD0782  [12]
 LDCM0466  CL73 HCT 116 C108(1.25); C1900(1.28); C2806(0.96); C5502(1.27)  LDD0783  [12]
 LDCM0467  CL74 HCT 116 C108(1.27); C1900(1.26); C2806(0.98); C5502(1.18)  LDD0784  [12]
 LDCM0469  CL76 HCT 116 C108(1.10); C5502(1.16)  LDD0786  [12]
 LDCM0470  CL77 HCT 116 C108(1.22); C5502(0.92)  LDD0787  [12]
 LDCM0471  CL78 HCT 116 C108(1.16); C5502(0.99)  LDD0788  [12]
 LDCM0472  CL79 HCT 116 C108(1.16); C5502(1.11)  LDD0789  [12]
 LDCM0473  CL8 HCT 116 C108(1.72); C2806(1.00); C5502(1.12)  LDD0790  [12]
 LDCM0474  CL80 HCT 116 C108(1.07); C5502(0.89)  LDD0791  [12]
 LDCM0475  CL81 HCT 116 C108(1.06); C5502(1.25)  LDD0792  [12]
 LDCM0476  CL82 HCT 116 C108(1.35); C5502(1.47)  LDD0793  [12]
 LDCM0477  CL83 HCT 116 C108(1.37); C5502(1.36)  LDD0794  [12]
 LDCM0478  CL84 HCT 116 C108(1.44); C5502(1.62)  LDD0795  [12]
 LDCM0479  CL85 HCT 116 C108(1.17); C5502(1.01)  LDD0796  [12]
 LDCM0480  CL86 HCT 116 C108(0.93); C5502(0.96)  LDD0797  [12]
 LDCM0481  CL87 HCT 116 C108(1.06); C5502(1.08)  LDD0798  [12]
 LDCM0482  CL88 HCT 116 C108(1.16); C5502(1.22)  LDD0799  [12]
 LDCM0483  CL89 HCT 116 C108(1.84); C5502(1.68)  LDD0800  [12]
 LDCM0484  CL9 HCT 116 C108(1.34); C2806(1.20); C5502(1.04)  LDD0801  [12]
 LDCM0485  CL90 HCT 116 C108(1.19); C5502(0.81)  LDD0802  [12]
 LDCM0486  CL91 HCT 116 C108(1.56); C5502(1.21)  LDD0803  [12]
 LDCM0487  CL92 HCT 116 C108(1.48); C5502(1.14)  LDD0804  [12]
 LDCM0488  CL93 HCT 116 C108(1.29); C5502(1.06)  LDD0805  [12]
 LDCM0489  CL94 HCT 116 C108(1.56); C5502(1.10)  LDD0806  [12]
 LDCM0490  CL95 HCT 116 C108(1.66); C5502(1.21)  LDD0807  [12]
 LDCM0491  CL96 HCT 116 C108(1.66); C5502(1.11)  LDD0808  [12]
 LDCM0492  CL97 HCT 116 C108(1.38); C5502(1.14)  LDD0809  [12]
 LDCM0493  CL98 HCT 116 C108(1.55); C5502(1.16)  LDD0810  [12]
 LDCM0494  CL99 HCT 116 C108(1.29); C5502(1.16)  LDD0811  [12]
 LDCM0634  CY-0357 Hep-G2 C2162(1.40); C1900(0.87); C1833(0.70)  LDD2228  [17]
 LDCM0495  E2913 HEK-293T C5502(0.99); C2806(1.06); C1833(1.16); C1900(1.02)  LDD1698  [29]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C2806(0.98); C5502(0.90); C1967(0.89); C1900(0.89)  LDD1702  [6]
 LDCM0175  Ethacrynic acid HeLa N.A.  LDD0440  [11]
 LDCM0572  Fragment10 MDA-MB-231 C108(1.86)  LDD1389  [30]
 LDCM0573  Fragment11 MDA-MB-231 C108(1.92)  LDD1391  [30]
 LDCM0574  Fragment12 MDA-MB-231 C108(1.62)  LDD1393  [30]
 LDCM0575  Fragment13 MDA-MB-231 C108(0.75)  LDD1395  [30]
 LDCM0576  Fragment14 MDA-MB-231 C108(1.40)  LDD1397  [30]
 LDCM0577  Fragment15 MDA-MB-231 C108(1.44)  LDD1399  [30]
 LDCM0579  Fragment20 MDA-MB-231 C108(1.75)  LDD1402  [30]
 LDCM0580  Fragment21 MDA-MB-231 C108(1.10)  LDD1404  [30]
 LDCM0582  Fragment23 MDA-MB-231 C108(1.46)  LDD1408  [30]
 LDCM0584  Fragment25 MDA-MB-231 C108(1.00)  LDD1411  [30]
 LDCM0578  Fragment27 MDA-MB-231 C108(0.99)  LDD1401  [30]
 LDCM0586  Fragment28 MDA-MB-231 C108(1.15)  LDD1415  [30]
 LDCM0587  Fragment29 MDA-MB-231 C108(1.42)  LDD1417  [30]
 LDCM0589  Fragment31 MDA-MB-231 C108(1.39)  LDD1421  [30]
 LDCM0590  Fragment32 MDA-MB-231 C108(1.88)  LDD1423  [30]
 LDCM0468  Fragment33 HCT 116 C108(1.17); C1900(1.34); C2806(1.03); C5502(1.27)  LDD0785  [12]
 LDCM0592  Fragment34 MDA-MB-231 C108(0.75)  LDD1427  [30]
 LDCM0593  Fragment35 MDA-MB-231 C108(0.86)  LDD1429  [30]
 LDCM0594  Fragment36 MDA-MB-231 C108(1.32)  LDD1431  [30]
 LDCM0596  Fragment38 MDA-MB-231 C108(1.16)  LDD1433  [30]
 LDCM0597  Fragment39 MDA-MB-231 C108(2.04)  LDD1435  [30]
 LDCM0566  Fragment4 MDA-MB-231 C108(1.41)  LDD1378  [30]
 LDCM0601  Fragment43 MDA-MB-231 C108(1.48)  LDD1441  [30]
 LDCM0602  Fragment44 MDA-MB-231 C108(0.80)  LDD1443  [30]
 LDCM0604  Fragment46 MDA-MB-231 C108(1.12)  LDD1445  [30]
 LDCM0605  Fragment47 MDA-MB-231 C108(1.03)  LDD1446  [30]
 LDCM0606  Fragment48 MDA-MB-231 C108(1.12)  LDD1447  [30]
 LDCM0608  Fragment50 MDA-MB-231 C108(1.13)  LDD1449  [30]
 LDCM0427  Fragment51 HCT 116 C108(2.42); C1900(2.22); C2806(1.49); C5502(1.21)  LDD0744  [12]
 LDCM0610  Fragment52 MDA-MB-231 C108(0.97)  LDD1452  [30]
 LDCM0612  Fragment54 MDA-MB-231 C108(1.17)  LDD1456  [30]
 LDCM0614  Fragment56 MDA-MB-231 C108(0.97)  LDD1458  [30]
 LDCM0568  Fragment6 MDA-MB-231 C108(1.24)  LDD1382  [30]
 LDCM0569  Fragment7 MDA-MB-231 C108(1.39)  LDD1383  [30]
 LDCM0570  Fragment8 MDA-MB-231 C108(1.99)  LDD1385  [30]
 LDCM0571  Fragment9 MDA-MB-231 C108(1.06)  LDD1387  [30]
 LDCM0107  IAA HeLa H187(0.00); H4313(0.00); H5535(0.00); H4308(0.00)  LDD0221  [21]
 LDCM0179  JZ128 PC-3 C2806(0.00); C108(0.00)  LDD0462  [9]
 LDCM0022  KB02 HCT 116 C5502(1.65)  LDD0080  [12]
 LDCM0023  KB03 HCT 116 C5502(1.16)  LDD0081  [12]
 LDCM0024  KB05 HCT 116 C5502(1.45)  LDD0082  [12]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C2806(1.10); C5502(0.85); C5382(1.01)  LDD2102  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C5502(0.64); C5382(0.58)  LDD2121  [6]
 LDCM0109  NEM HeLa H187(0.00); H5535(0.00); H4308(0.00); H4313(0.00)  LDD0223  [21]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C2806(1.18); C5502(0.69); C1833(1.05); C5382(0.50)  LDD2089  [6]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C5502(1.29); C5382(1.18)  LDD2090  [6]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C2806(1.07); C5502(0.87); C5382(0.81)  LDD2092  [6]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C5382(1.05)  LDD2093  [6]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C5382(1.05)  LDD2094  [6]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C5502(0.72); C5382(0.66)  LDD2096  [6]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C5382(0.84)  LDD2097  [6]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C2806(0.62); C5502(0.81); C5382(0.86)  LDD2098  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C2806(1.36); C5502(1.08); C1833(1.26); C5382(0.89)  LDD2099  [6]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C2806(0.74); C5382(0.95)  LDD2100  [6]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C5382(1.20)  LDD2101  [6]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C2806(0.96); C5382(0.74)  LDD2104  [6]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C5502(1.00); C5382(1.51)  LDD2105  [6]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C5502(0.62); C5382(0.61)  LDD2106  [6]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C2806(1.00); C5502(0.85); C1833(1.17); C5382(0.70)  LDD2107  [6]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C2806(1.23); C1833(0.81); C5382(0.99)  LDD2108  [6]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C2806(1.18); C5502(0.96); C5382(0.92)  LDD2109  [6]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C5502(1.20); C5382(1.74)  LDD2110  [6]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C2806(1.32); C5502(0.91); C5382(0.74)  LDD2111  [6]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C5502(0.52); C1967(0.58); C1900(0.58); C5382(0.59)  LDD2114  [6]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C5502(0.65); C5382(0.56)  LDD2115  [6]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C2806(1.84); C5502(0.85); C5382(1.00)  LDD2116  [6]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C5502(0.80); C5382(0.84)  LDD2118  [6]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C2806(2.63); C5382(2.55)  LDD2119  [6]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C5502(1.00); C5382(0.98)  LDD2120  [6]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C5502(0.84); C5382(0.87)  LDD2122  [6]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C2806(0.91); C5502(0.79); C1833(1.05); C1967(0.92)  LDD2123  [6]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C5502(0.83); C5382(0.92)  LDD2124  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C2806(0.91); C5502(0.82); C1833(0.59); C5382(0.71)  LDD2125  [6]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C5382(0.77)  LDD2126  [6]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C5502(1.06); C5382(0.80)  LDD2127  [6]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C5502(0.83); C5382(0.89)  LDD2128  [6]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C2806(1.55); C5502(0.96); C5382(0.79)  LDD2129  [6]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C2806(1.28); C5502(0.57); C5382(0.65)  LDD2133  [6]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C2806(0.48); C5382(0.60)  LDD2134  [6]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C5502(0.99)  LDD2135  [6]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C2806(0.98); C5502(1.03); C1833(1.19); C5382(0.76)  LDD2136  [6]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C2806(0.88); C5502(0.89); C5382(0.67)  LDD2137  [6]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C2806(2.13); C5382(1.40)  LDD1700  [6]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C2806(0.99); C5502(0.73); C1833(0.99); C5382(0.66)  LDD2140  [6]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C2806(1.08); C5502(0.57); C1833(0.72); C1967(1.10)  LDD2141  [6]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C5502(1.08); C5382(1.03)  LDD2143  [6]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C5502(3.63); C5382(3.78)  LDD2144  [6]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C5502(2.10)  LDD2145  [6]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C2806(0.95); C5502(0.84); C5382(0.71)  LDD2146  [6]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C5502(2.24); C5382(3.22)  LDD2147  [6]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C2806(0.52); C5502(0.41)  LDD2148  [6]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C5502(0.88); C5382(1.01)  LDD2149  [6]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C2806(0.77); C5502(0.47); C1833(0.84); C5382(0.36)  LDD2150  [6]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C5382(1.70)  LDD2153  [6]
 LDCM0021  THZ1 HCT 116 C5502(0.99)  LDD2173  [12]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Polynucleotide 5'-hydroxyl-kinase NOL9 (NOL9) Clp1 family Q5SY16
Epidermal growth factor receptor (EGFR) Tyr protein kinase family P00533
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein S100-A10 (S100A10) S-100 family P60903

References

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Mass spectrometry data entry: PXD028270
6 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
7 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
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10 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
11 Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function. Mol Pharm. 2018 Jun 4;15(6):2413-2422. doi: 10.1021/acs.molpharmaceut.8b00250. Epub 2018 May 15.
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13 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
14 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
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Mass spectrometry data entry: PXD006095 , PXD006096
16 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
17 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
18 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD038010
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Mass spectrometry data entry: PXD044402
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