Probe ID	LDPC0153
Probe Name	CY4
Probe Type	ABPP Probe
Structure
	2D MOL
Ro5 Violations (Lipinski): 0	Molecular Weight (mw)		214.289
	Lipid-water partition coefficient (xlogp)		3.27911
	Rotatable Bond Count (rotbonds)		3
	Hydrogen Bond Donor Count (hbonddonor)		0
	Hydrogen Bond Acceptor Count (hbondacc)		2
Chemical Identifiers	Formula C13H10OS Canonical SMILES C#CCOc1ccc(-c2c(C)c2=S)cc1 InChI InChI=1S/C13H10OS/c1-3-8-14-11-6-4-10(5-7-11)12-9(2)13(12)15/h1,4-7H,8H2,2H3 InChIKey HNRXTESRYNBUJY-UHFFFAOYSA-N

255 Enzyme Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID 26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 100.00  LDD0244  26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 100.00  LDD0244  26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 15.65  LDD0244  26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 100.00  LDD0244  26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 100.00  LDD0244  3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 100.00  LDD0244  6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 100.00  LDD0244  Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 100.00  LDD0244  Aconitate hydratase, mitochondrial (ACO2) LDTP10982 100.00  LDD0244  Actin, alpha skeletal muscle (ACTA1) LDTP05073 100.00  LDD0244  Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) LDTP16274 100.00  LDD0244  Adenosylhomocysteinase (AHCY) LDTP03242 15.99  LDD0244  ADP-ribosylation factor 4 (ARF4) LDTP02942 100.00  LDD0244  ADP-sugar pyrophosphatase (NUDT5) LDTP13462 100.00  LDD0244  Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 100.00  LDD0244  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 100.00  LDD0244  Alpha-enolase (ENO1) LDTP02159 2.45  LDD0244  Antigen peptide transporter 1 (TAP1) LDTP05408 100.00  LDD0244  Antigen peptide transporter 2 (TAP2) LDTP05409 100.00  LDD0244  Antiviral innate immune response receptor RIG-I (RIGI) LDTP01675 100.00  LDD0244  Apoptosis-enhancing nuclease (AEN) LDTP09536 K179; K183  LDD0247  Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 100.00  LDD0244  Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 4.69  LDD0244  Atlastin-3 (ATL3) LDTP07362 100.00  LDD0244  ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 100.00  LDD0244  ATP-binding cassette sub-family D member 3 (ABCD3) LDTP03424 100.00  LDD0244  ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 100.00  LDD0244  ATP-binding cassette sub-family G member 1 (ABCG1) LDTP04069 Q64  LDD0247  ATP-citrate synthase (ACLY) LDTP04561 100.00  LDD0244  ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 100.00  LDD0244  ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 13.85  LDD0244  ATP-dependent RNA helicase A (DHX9) LDTP05550 23.44  LDD0244  ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 100.00  LDD0244  ATP-dependent RNA helicase DDX42 (DDX42) LDTP08369 100.00  LDD0244  ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 100.00  LDD0244  Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 4.04  LDD0244  Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 100.00  LDD0244  C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 100.00  LDD0244  CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 100.00  LDD0244  Calcyclin-binding protein (CACYBP) LDTP12163 100.00  LDD0244  Calpain-1 catalytic subunit (CAPN1) LDTP02204 100.00  LDD0244  Calpain-2 catalytic subunit (CAPN2) LDTP02911 100.00  LDD0244  Carbonic anhydrase 6 (CA6) LDTP03215 Y59  LDD0247  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 100.00  LDD0244  Cell division control protein 42 homolog (CDC42) LDTP04886 100.00  LDD0244  Ceramide synthase 2 (CERS2) LDTP10329 100.00  LDD0244  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 100.00  LDD0244  Chromodomain-helicase-DNA-binding protein 8 (CHD8) LDTP12252 C1655  LDD0247  Citrate synthase, mitochondrial (CS) LDTP01205 100.00  LDD0244  COP9 signalosome complex subunit 3 (COPS3) LDTP13675 100.00  LDD0244  CTP synthase 1 (CTPS1) LDTP02922 100.00  LDD0244  Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 100.00  LDD0244  Cyclic GMP-AMP synthase (CGAS) LDTP08974 K21; S23; T18; R28  LDD0247  Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 100.00  LDD0244  Cytochrome b-c1 complex subunit Rieske, mitochondrial (UQCRFS1) LDTP04144 100.00  LDD0244  Cytochrome b5 type B (CYB5B) LDTP00697 100.00  LDD0244  Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 100.00  LDD0244  Cytochrome P450 4X1 (CYP4X1) LDTP15397 K266  LDD0247  Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 100.00  LDD0244  Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 100.00  LDD0244  Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) LDTP04646 100.00  LDD0244  Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 100.00  LDD0244  Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) LDTP00403 M743; M746; Y741  LDD0247  DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 100.00  LDD0244  DNA replication licensing factor MCM2 (MCM2) LDTP04286 N303  LDD0247  DNA replication licensing factor MCM3 (MCM3) LDTP03316 100.00  LDD0244  DNA replication licensing factor MCM5 (MCM5) LDTP03681 100.00  LDD0244  DNA topoisomerase 2-alpha (TOP2A) LDTP02568 100.00  LDD0244  DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 7.99  LDD0244  DNA-directed RNA polymerase II subunit RPB2 (POLR2B) LDTP03564 100.00  LDD0244  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 100.00  LDD0244  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) LDTP09388 100.00  LDD0244  Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 100.00  LDD0244  Dynamin-1-like protein (DNM1L) LDTP00273 100.00  LDD0244  Dynamin-2 (DNM2) LDTP04374 100.00  LDD0244  Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 100.00  LDD0244  Dystrobrevin beta (DTNB) LDTP01094 K133; K143; M135; M139  LDD0247  E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 100.00  LDD0244  E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 100.00  LDD0244  E3 ubiquitin-protein ligase RNF135 (RNF135) LDTP08449 H71; K74; Q69; R73  LDD0247  E3 ubiquitin-protein ligase SH3RF2 (SH3RF2) LDTP09493 Y648  LDD0247  E3 ubiquitin-protein ligase TRIM15 (TRIM15) LDTP11579 R190; R192  LDD0247  E3 ubiquitin-protein ligase TRIM31 (TRIM31) LDTP11573 N68; N73  LDD0247  E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 100.00  LDD0244  E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) LDTP06098 100.00  LDD0244  Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 4.44  LDD0244  Elongation factor 2 (EEF2) LDTP02672 5.57  LDD0244  Elongation factor Tu, mitochondrial (TUFM) LDTP04251 100.00  LDD0244  Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 7.77  LDD0244  Ephrin type-A receptor 2 (EPHA2) LDTP03474 100.00  LDD0244  Epidermal growth factor receptor (EGFR) LDTP01785 100.00  LDD0244  ERO1-like protein alpha (ERO1A) LDTP10386 100.00  LDD0244  Estradiol 17-beta-dehydrogenase 11 (HSD17B11) LDTP09063 100.00  LDD0244  Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 2.90  LDD0244  Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 100.00  LDD0244  Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) LDTP03915 30.69  LDD0244  Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 100.00  LDD0244  Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 100.00  LDD0244  FACT complex subunit SPT16 (SUPT16H) LDTP14109 100.00  LDD0244  Farnesyl pyrophosphate synthase (FDPS) LDTP02721 100.00  LDD0244  Fatty acid synthase (FASN) LDTP04243 100.00  LDD0244  Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 3.39  LDD0244  Fumarate hydratase, mitochondrial (FH) LDTP02235 100.00  LDD0244  Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3) LDTP01411 Q321; Q323; Q325  LDD0247  General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) LDTP03000 Q677; Q683  LDD0247  Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 100.00  LDD0244  Glucose-6-phosphate isomerase (GPI) LDTP02162 100.00  LDD0244  Glutamate dehydrogenase 1, mitochondrial (GLUD1) LDTP01768 100.00  LDD0244  Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 100.00  LDD0244  Glutathione S-transferase Mu 1 (GSTM1) LDTP02350 100.00  LDD0244  Glutathione S-transferase Mu 3 (GSTM3) LDTP03103 100.00  LDD0244  Glutathione S-transferase omega-1 (GSTO1) LDTP05128 100.00  LDD0244  Glutathione S-transferase P (GSTP1) LDTP02333 4.11  LDD0244  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 2.15  LDD0244  Glycine--tRNA ligase (GARS1) LDTP03946 100.00  LDD0244  Glycogen phosphorylase, brain form (PYGB) LDTP02552 100.00  LDD0244  Glycogen phosphorylase, liver form (PYGL) LDTP02161 N24  LDD0247  GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 100.00  LDD0244  GTP-binding nuclear protein Ran (RAN) LDTP05007 3.70  LDD0244  Guanine nucleotide-binding protein-like 3 (GNL3) LDTP11297 100.00  LDD0244  Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 5.68  LDD0244  Heme oxygenase 2 (HMOX2) LDTP03540 100.00  LDD0244  Holocytochrome c-type synthase (HCCS) LDTP04581 100.00  LDD0244  Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 100.00  LDD0244  Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 (NAALADL2) LDTP06936 D193; M194  LDD0247  Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 17.02  LDD0244  Kinesin-like protein KIF2C (KIF2C) LDTP10935 100.00  LDD0244  L-lactate dehydrogenase A chain (LDHA) LDTP01766 2.49  LDD0244  L-lactate dehydrogenase B chain (LDHB) LDTP02179 4.02  LDD0244  Lysine-specific demethylase 2B (KDM2B) LDTP09254 D392; E387; S388  LDD0247  Lysine-specific histone demethylase 1A (KDM1A) LDTP00957 D303  LDD0247  Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 100.00  LDD0244  Lysosomal acid glucosylceramidase (GBA1) LDTP02005 D321; D322  LDD0247  Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 100.00  LDD0244  Methionine aminopeptidase 2 (METAP2) LDTP04375 100.00  LDD0244  Methylmalonyl-CoA mutase, mitochondrial (MMUT) LDTP03150 K457; M452; M455  LDD0247  Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 100.00  LDD0244  Minor histocompatibility antigen H13 (HM13) LDTP09396 100.00  LDD0244  Misshapen-like kinase 1 (MINK1) LDTP08863 S682; S687; T681; N680  LDD0247  Multifunctional protein CAD (CAD) LDTP03401 100.00  LDD0244  Myosin-9 (MYH9) LDTP03764 6.02  LDD0244  N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 100.00  LDD0244  NADH-cytochrome b5 reductase 3 (CYB5R3) LDTP01770 5.68  LDD0244  NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1) LDTP03433 D637; D640; T633; T638  LDD0247  Nardilysin (NRDC) LDTP00886 100.00  LDD0244  NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 D37; E40  LDD0247  Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 100.00  LDD0244  Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 2.32  LDD0244  Nitric oxide synthase 3 (NOS3) LDTP03491 Q435  LDD0247  Nucleolar RNA helicase 2 (DDX21) LDTP12469 2.10  LDD0244  Nucleoside diphosphate kinase A (NME1) LDTP02796 9.43  LDD0244  Nucleoside diphosphate kinase B (NME2) LDTP03169 100.00  LDD0244  Obscurin (OBSCN) LDTP07209 C3327; E3328; Q3330; R3332  LDD0247  Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 4.30  LDD0244  Peptidyl-prolyl cis-trans isomerase B (PPIB) LDTP03216 12.12  LDD0244  Peroxiredoxin-1 (PRDX1) LDTP05503 7.10  LDD0244  Peroxiredoxin-2 (PRDX2) LDTP03626 100.00  LDD0244  Peroxiredoxin-4 (PRDX4) LDTP05773 100.00  LDD0244  Peroxiredoxin-6 (PRDX6) LDTP03510 100.00  LDD0244  Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 100.00  LDD0244  Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 100.00  LDD0244  Phosphoglucomutase-1 (PGM1) LDTP03818 100.00  LDD0244  Phosphoglycerate kinase 1 (PGK1) LDTP01787 2.85  LDD0244  Phosphoglycerate mutase 1 (PGAM1) LDTP02963 4.21  LDD0244  Phosphopentomutase (PGM2) LDTP10326 100.00  LDD0244  Plasma membrane calcium-transporting ATPase 1 (ATP2B1) LDTP03024 100.00  LDD0244  Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 100.00  LDD0244  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 D100; E90; M87; M91  LDD0247  Pre-rRNA-processing protein TSR1 homolog (TSR1) LDTP14888 100.00  LDD0244  Probable ATP-dependent RNA helicase DDX6 (DDX6) LDTP03348 100.00  LDD0244  Probable E3 ubiquitin-protein ligase HECTD4 (HECTD4) LDTP14048 M3567; T3565  LDD0247  Probable global transcription activator SNF2L2 (SMARCA2) LDTP04421 M970  LDD0247  Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 100.00  LDD0244  Prolyl endopeptidase (PREP) LDTP04163 100.00  LDD0244  Proteasome subunit beta type-2 (PSMB2) LDTP04285 100.00  LDD0244  Proteasome subunit beta type-5 (PSMB5) LDTP03419 100.00  LDD0244  Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 100.00  LDD0244  Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 100.00  LDD0244  Protein disulfide-isomerase (P4HB) LDTP02188 100.00  LDD0244  Protein disulfide-isomerase A3 (PDIA3) LDTP03521 3.52  LDD0244  Protein phosphatase 1G (PPM1G) LDTP00616 100.00  LDD0244  Protein phosphatase methylesterase 1 (PPME1) LDTP14092 100.00  LDD0244  Protein PML (PML) LDTP03496 100.00  LDD0244  Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 5.03  LDD0244  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 100.00  LDD0244  Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 100.00  LDD0244  Putative phosphatidylinositol 4-kinase alpha-like protein P2 (PI4KAP2) LDTP16582 C571  LDD0247  Putative tyrosine carboxypeptidase MATCAP2 (MATCAP2) LDTP15492 R354  LDD0247  Putative uncharacterized protein MYH16 (MYH16) LDTP19970 T529; T532; T533  LDD0247  Pyruvate kinase PKM (PKM) LDTP02733 3.30  LDD0244  Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 100.00  LDD0244  Ras-related protein Rab-14 (RAB14) LDTP04901 100.00  LDD0244  Ras-related protein Rab-19 (RAB19) LDTP14338 D15; K19; Y16  LDD0247  Ras-related protein Rab-1A (RAB1A) LDTP05006 100.00  LDD0244  Ras-related protein Rab-5C (RAB5C) LDTP04398 100.00  LDD0244  Ras-related protein Rab-7a (RAB7A) LDTP04399 100.00  LDD0244  Ras-related protein Rab-8A (RAB8A) LDTP04888 100.00  LDD0244  Receptor-interacting serine/threonine-protein kinase 4 (RIPK4) LDTP04782 E528; H524; R529  LDD0247  RecQ-like DNA helicase BLM (BLM) LDTP04600 E781; E785  LDD0247  Retinol dehydrogenase 11 (RDH11) LDTP09364 100.00  LDD0244  Rho-related GTP-binding protein RhoG (RHOG) LDTP05195 100.00  LDD0244  Rhomboid-related protein 3 (RHBDL3) LDTP14734 Q113  LDD0247  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 100.00  LDD0244  S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 100.00  LDD0244  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 90.17  LDD0244  Septin-11 (SEPTIN11) LDTP12667 100.00  LDD0244  Septin-2 (SEPTIN2) LDTP06279 100.00  LDD0244  Septin-7 (SEPTIN7) LDTP06513 100.00  LDD0244  Septin-9 (SEPTIN9) LDTP13272 100.00  LDD0244  Serine-protein kinase ATM (ATM) LDTP05822 N1122  LDD0247  Serine/threonine-protein kinase 10 (STK10) LDTP01420 100.00  LDD0244  Serine/threonine-protein kinase TAO3 (TAOK3) LDTP11829 E825; E827  LDD0247  Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B) LDTP05232 Q55; Q60  LDD0247  Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 100.00  LDD0244  Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PPP2R3B) LDTP14142 C35  LDD0247  Small ribosomal subunit protein uS3 (RPS3) LDTP03223 3.74  LDD0244  Spastin (SPAST) LDTP13137 M483  LDD0247  Spermidine synthase (SRM) LDTP03008 100.00  LDD0244  Sphingomyelin phosphodiesterase 4 (SMPD4) LDTP12776 C68; Q69  LDD0247  Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 2.16  LDD0244  Sterol O-acyltransferase 1 (SOAT1) LDTP03769 100.00  LDD0244  Sulfhydryl oxidase 2 (QSOX2) LDTP07813 100.00  LDD0244  Sulfotransferase 1B1 (SULT1B1) LDTP00842 T85  LDD0247  Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 100.00  LDD0244  Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 111.95  LDD0244  Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 100.00  LDD0244  Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 (TSTD3) LDTP18983 Y32  LDD0247  Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 100.00  LDD0244  Thymidine kinase, cytosolic (TK1) LDTP02022 100.00  LDD0244  Transaldolase (TALDO1) LDTP03847 100.00  LDD0244  Transcription activator BRG1 (SMARCA4) LDTP04422 100.00  LDD0244  Transcription intermediary factor 1-beta (TRIM28) LDTP05808 100.00  LDD0244  Transforming protein RhoA (RHOA) LDTP04927 100.00  LDD0244  Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 4.38  LDD0244  Transketolase (TKT) LDTP03487 4.07  LDD0244  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 100.00  LDD0244  Triosephosphate isomerase (TPI1) LDTP04851 4.35  LDD0244  Tubulin alpha chain-like 3 (TUBAL3) LDTP00100 K408  LDD0247  Tubulin alpha-1B chain (TUBA1B) LDTP05074 2.41  LDD0244  Tumor susceptibility gene 101 protein (TSG101) LDTP10987 R368; R374  LDD0247  Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 100.00  LDD0244  Tyrosine-protein kinase receptor Tie-1 (TIE1) LDTP03766 Y1070  LDD0247  Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) LDTP02935 100.00  LDD0244  U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 100.00  LDD0244  Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 6.90  LDD0244  Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 100.00  LDD0244  V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 100.00  LDD0244  Valine--tRNA ligase (VARS1) LDTP03366 7.50  LDD0244  Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 100.00  LDD0244  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 100.00  LDD0244  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 100.00  LDD0244  Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 100.00  LDD0244  X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 100.00  LDD0244  X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 6.86  LDD0244  [F-actin]-monooxygenase MICAL2 (MICAL2) LDTP01439 100.00  LDD0244  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 255 Enzyme
103 Transporter and channel Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID 14-3-3 protein epsilon (YWHAE) LDTP04969 5.46  LDD0244  14-3-3 protein gamma (YWHAG) LDTP04953 100.00  LDD0244  14-3-3 protein theta (YWHAQ) LDTP03385 100.00  LDD0244  14-3-3 protein zeta/delta (YWHAZ) LDTP05043 5.84  LDD0244  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 100.00  LDD0244  ADP/ATP translocase 2 (SLC25A5) LDTP02087 3.17  LDD0244  Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 100.00  LDD0244  Annexin A1 (ANXA1) LDTP02010 100.00  LDD0244  Annexin A6 (ANXA6) LDTP02247 100.00  LDD0244  AP-2 complex subunit beta (AP2B1) LDTP05038 100.00  LDD0244  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 100.00  LDD0244  ATP-binding cassette sub-family F member 1 (ABCF1) LDTP09149 10.80  LDD0244  B-cell receptor-associated protein 31 (BCAP31) LDTP04426 100.00  LDD0244  Calnexin (CANX) LDTP03405 100.00  LDD0244  Calreticulin (CALR) LDTP03402 100.00  LDD0244  Caveolin-1 (CAV1) LDTP05394 4.85  LDD0244  CD151 antigen (CD151) LDTP04187 100.00  LDD0244  CD63 antigen (CD63) LDTP02320 100.00  LDD0244  Chloride intracellular channel protein 1 (CLIC1) LDTP00244 3.11  LDD0244  Chloride intracellular channel protein 4 (CLIC4) LDTP14222 100.00  LDD0244  Clathrin heavy chain 1 (CLTC) LDTP05252 2.44  LDD0244  Copine-1 (CPNE1) LDTP10989 100.00  LDD0244  Cystatin-B (CSTB) LDTP02009 100.00  LDD0244  Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 100.00  LDD0244  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 100.00  LDD0244  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 100.00  LDD0244  Dysferlin (DYSF) LDTP01355 M1053  LDD0247  EF-hand calcium-binding domain-containing protein 9 (EFCAB9) LDTP16715 Q137; Q139  LDD0247  EH domain-containing protein 1 (EHD1) LDTP11934 100.00  LDD0244  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 100.00  LDD0244  Equilibrative nucleoside transporter 1 (SLC29A1) LDTP10985 100.00  LDD0244  Erlin-1 (ERLIN1) LDTP01234 T171  LDD0247  Exportin-1 (XPO1) LDTP00501 8.54  LDD0244  Exportin-2 (CSE1L) LDTP04662 100.00  LDD0244  Exportin-5 (XPO5) LDTP12142 100.00  LDD0244  Filamin-A (FLNA) LDTP03107 13.66  LDD0244  Filamin-B (FLNB) LDTP01197 100.00  LDD0244  Filamin-C (FLNC) LDTP06103 100.00  LDD0244  Flotillin-1 (FLOT1) LDTP01366 100.00  LDD0244  Gamma-aminobutyric acid receptor subunit rho-1 (GABRR1) LDTP03266 M177  LDD0247  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 100.00  LDD0244  Guanine nucleotide-binding protein subunit alpha-11 (GNA11) LDTP03506 100.00  LDD0244  Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 4.55  LDD0244  Importin subunit beta-1 (KPNB1) LDTP06242 42.48  LDD0244  Importin-4 (IPO4) LDTP09515 100.00  LDD0244  Importin-5 (IPO5) LDTP00266 100.00  LDD0244  Importin-7 (IPO7) LDTP01574 100.00  LDD0244  Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2) LDTP06152 K1110; Y1109; Q1111  LDD0247  Kinesin-1 heavy chain (KIF5B) LDTP03664 100.00  LDD0244  Kinesin-like protein KIF16B (KIF16B) LDTP10534 E691; Q693  LDD0247  Large neutral amino acids transporter small subunit 1 (SLC7A5) LDTP05305 100.00  LDD0244  Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 100.00  LDD0244  Low-density lipoprotein receptor-related protein 2 (LRP2) LDTP05218 D2330  LDD0247  MICOS complex subunit MIC60 (IMMT) LDTP06660 100.00  LDD0244  Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 100.00  LDD0244  Mitochondrial basic amino acids transporter (SLC25A29) LDTP08982 Y39  LDD0247  Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 100.00  LDD0244  Mitochondrial glutamate carrier 1 (SLC25A22) LDTP12078 100.00  LDD0244  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 100.00  LDD0244  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 100.00  LDD0244  Monocarboxylate transporter 4 (SLC16A3) LDTP00635 100.00  LDD0244  Myeloid-associated differentiation marker (MYADM) LDTP10806 100.00  LDD0244  Myoferlin (MYOF) LDTP12916 100.00  LDD0244  Neutral amino acid transporter B(0) (SLC1A5) LDTP06462 100.00  LDD0244  Nuclear pore complex protein Nup155 (NUP155) LDTP01295 100.00  LDD0244  Nuclear pore complex protein Nup205 (NUP205) LDTP09825 100.00  LDD0244  Nuclear pore complex protein Nup88 (NUP88) LDTP10897 100.00  LDD0244  Nuclear pore complex protein Nup93 (NUP93) LDTP08769 100.00  LDD0244  Protein patched homolog 1 (PTCH1) LDTP05956 C1437; D1434  LDD0247  Protein RER1 (RER1) LDTP00590 100.00  LDD0244  Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 6.60  LDD0244  Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 100.00  LDD0244  Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 100.00  LDD0244  Rapamycin-insensitive companion of mTOR (RICTOR) LDTP07626 T1629  LDD0247  Secretory carrier-associated membrane protein 3 (SCAMP3) LDTP00451 100.00  LDD0244  Sideroflexin-1 (SFXN1) LDTP12090 100.00  LDD0244  Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 2.90  LDD0244  Sodium/bile acid cotransporter 5 (SLC10A5) LDTP17204 D140; H138; Q134; R141  LDD0247  Sodium/hydrogen exchanger 9B2 (SLC9B2) LDTP08223 S454; W457  LDD0247  Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 100.00  LDD0244  Solute carrier family 25 member 3 (SLC25A3) LDTP05238 8.24  LDD0244  Solute carrier family 4 member 11 (SLC4A11) LDTP09066 K116; K118  LDD0247  Sorting nexin-17 (SNX17) LDTP06288 K253; K256  LDD0247  Sorting nexin-4 (SNX4) LDTP01531 C172  LDD0247  Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 100.00  LDD0244  SUN domain-containing protein 1 (SUN1) LDTP01454 100.00  LDD0244  Surfeit locus protein 4 (SURF4) LDTP00592 100.00  LDD0244  T-complex protein 1 subunit delta (CCT4) LDTP04391 3.47  LDD0244  Talin-1 (TLN1) LDTP14031 45.01  LDD0244  Talin-2 (TLN2) LDTP14057 D1068; E1075; K1070; S1076  LDD0247  Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 100.00  LDD0244  Transferrin receptor protein 1 (TFRC) LDTP01969 100.00  LDD0244  Transient receptor potential cation channel subfamily M member 1 (TRPM1) LDTP08074 D1370  LDD0247  Transient receptor potential cation channel subfamily V member 4 (TRPV4) LDTP12168 K344; D347; M345; Y346  LDD0247  Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 100.00  LDD0244  Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 100.00  LDD0244  Transmembrane 9 superfamily member 4 (TM9SF4) LDTP09789 100.00  LDD0244  Transmembrane protein 214 (TMEM214) LDTP07477 100.00  LDD0244  Transmembrane protein 245 (TMEM245) LDTP15979 100.00  LDD0244  Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 100.00  LDD0244  Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 100.00  LDD0244  Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 7.02  LDD0244  Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 10.61  LDD0244  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 103 Transporter and channel
18 Transcription factor Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID AT-rich interactive domain-containing protein 1A (ARID1A) LDTP00350 T2150  LDD0247  DNA-binding protein RFX8 (RFX8) LDTP17500 D522  LDD0247  eIF5-mimic protein 2 (BZW1) LDTP07940 D198; D212  LDD0247  FACT complex subunit SSRP1 (SSRP1) LDTP05577 100.00  LDD0244  High mobility group protein B1 (HMGB1) LDTP02343 32.20  LDD0244  Hypoxia-inducible factor 1-alpha (HIF1A) LDTP06601 Y305  LDD0247  Interferon-inducible protein AIM2 (AIM2) LDTP00459 Y92  LDD0247  Metastasis-associated protein MTA2 (MTA2) LDTP01414 100.00  LDD0244  Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 100.00  LDD0244  Protein Wiz (WIZ) LDTP01674 T1337; T1340  LDD0247  Signal transducer and activator of transcription 3 (STAT3) LDTP03903 100.00  LDD0244  Transcription factor p65 (RELA) LDTP05417 100.00  LDD0244  Zinc finger protein 235 (ZNF235) LDTP14845 Q74  LDD0247  Zinc finger protein 263 (ZNF263) LDTP00499 C467; Y462  LDD0247  Zinc finger protein 268 (ZNF268) LDTP06157 Q570; Q575  LDD0247  Zinc finger protein 30 (ZNF30) LDTP14646 H446  LDD0247  Zinc finger protein 479 (ZNF479) LDTP15750 H160; Y162  LDD0247  Zinc finger protein 577 (ZNF577) LDTP15881 T5  LDD0247  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 18 Transcription factor
2 GPCR Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID Adhesion G protein-coupled receptor E5 (ADGRE5) LDTP04221 100.00  LDD0244  Metabotropic glutamate receptor 4 (GRM4) LDTP06218 M869; S870; T868  LDD0247  ------------------------------------------------------------------------------------
3 Immunoglobulin Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 100.00  LDD0244  Immunoglobulin-like and fibronectin type III domain-containing protein 1 (IGFN1) LDTP08283 Y191  LDD0247  Tapasin (TAPBP) LDTP00671 100.00  LDD0244  ------------------------------------------------------------------------------------
1 Cytokine and receptor Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID C-X-C motif chemokine 2 (CXCL2) LDTP03018 M92  LDD0247  ------------------------------------------------------------------------------------
270 Other Labeled by This Probe Target Name Target ID Binding Site(Ratio) Interaction ID 14-3-3 protein eta (YWHAH) LDTP05442 100.00  LDD0244  182 kDa tankyrase-1-binding protein (TNKS1BP1) LDTP11597 100.00  LDD0244  26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 100.00  LDD0244  26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 100.00  LDD0244  A-kinase anchor protein 9 (AKAP9) LDTP11033 D2269; D2275; S2268; S2272  LDD0247  Actin filament-associated protein 1 (AFAP1) LDTP08885 100.00  LDD0244  Actin-related protein 2 (ACTR2) LDTP04903 100.00  LDD0244  Actin-related protein 2/3 complex subunit 1B (ARPC1B) LDTP00550 19.20  LDD0244  Actin-related protein 2/3 complex subunit 2 (ARPC2) LDTP00551 9.60  LDD0244  Actin-related protein 2/3 complex subunit 4 (ARPC4) LDTP04844 100.00  LDD0244  Actin-related protein 3 (ACTR3) LDTP04902 100.00  LDD0244  Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 100.00  LDD0244  Alpha-actinin-1 (ACTN1) LDTP02631 5.38  LDD0244  Alpha-actinin-4 (ACTN4) LDTP00843 2.86  LDD0244  Anillin (ANLN) LDTP12443 100.00  LDD0244  Ankyrin repeat and EF-hand domain-containing protein 1 (ANKEF1) LDTP16097 C19  LDD0247  AP-5 complex subunit zeta-1 (AP5Z1) LDTP00735 C662  LDD0247  Ataxin-10 (ATXN10) LDTP13091 100.00  LDD0244  Bardet-Biedl syndrome 10 protein (BBS10) LDTP09304 T565; T568; N561; N566  LDD0247  Biorientation of chromosomes in cell division protein 1-like 1 (BOD1L1) LDTP09196 D853  LDD0247  Bridge-like lipid transfer protein family member 2 (BLTP2) LDTP06172 Q2122  LDD0247  Bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) LDTP13342 D1723; D1726  LDD0247  C-Maf-inducing protein (CMIP) LDTP08620 T639; T642  LDD0247  CCR4-NOT transcription complex subunit 1 (CNOT1) LDTP00078 100.00  LDD0244  CDGSH iron-sulfur domain-containing protein 3, mitochondrial (CISD3) LDTP02398 100.00  LDD0244  Charged multivesicular body protein 4b (CHMP4B) LDTP11899 D31; T32  LDD0247  Ciliary rootlet coiled-coil protein 2 (CROCC2) LDTP18999 E530; Q528; R532  LDD0247  Clustered mitochondria protein homolog (CLUH) LDTP14486 100.00  LDD0244  Coactosin-like protein (COTL1) LDTP06024 100.00  LDD0244  Coatomer subunit alpha (COPA) LDTP04571 100.00  LDD0244  Coatomer subunit beta (COPB1) LDTP04570 39.64  LDD0244  Coatomer subunit delta (ARCN1) LDTP04181 22.36  LDD0244  Coatomer subunit gamma-1 (COPG1) LDTP14216 100.00  LDD0244  Cofilin-1 (CFL1) LDTP03244 14.29  LDD0244  Coiled-coil domain-containing protein 169 (CCDC169) LDTP16681 E146  LDD0247  Coiled-coil domain-containing protein 24 (CCDC24) LDTP08869 E13; E14  LDD0247  COMM domain-containing protein 3 (COMMD3) LDTP13118 Y104  LDD0247  Condensin complex subunit 1 (NCAPD2) LDTP06281 100.00  LDD0244  Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 M69  LDD0247  Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A) LDTP12883 100.00  LDD0244  Cyclin-J (CCNJ) LDTP17232 Y30  LDD0247  Cytochrome c oxidase copper chaperone (COX17) LDTP06030 100.00  LDD0244  Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 4.87  LDD0244  Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 100.00  LDD0244  Dedicator of cytokinesis protein 8 (DOCK8) LDTP09189 N1887; N1889  LDD0247  Dickkopf-related protein 1 (DKK1) LDTP01457 C220; H223  LDD0247  Divergent protein kinase domain 2A (DIPK2A) LDTP09143 Y421  LDD0247  DnaJ homolog subfamily C member 7 (DNAJC7) LDTP10920 100.00  LDD0244  Dynein axonemal heavy chain 5 (DNAH5) LDTP09482 Q273  LDD0247  Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 100.00  LDD0244  Dynein regulatory complex protein 1 (DRC1) LDTP10580 Q246; Q249  LDD0247  Dynein regulatory complex protein 9 (IQCG) LDTP11689 Q222  LDD0247  Dystonin (DST) LDTP05386 D3722  LDD0247  Early endosome antigen 1 (EEA1) LDTP06310 C1102  LDD0247  ELAV-like protein 1 (ELAVL1) LDTP06450 100.00  LDD0244  Elongation factor 1-delta (EEF1D) LDTP03499 100.00  LDD0244  Elongation factor 1-gamma (EEF1G) LDTP03367 2.07  LDD0244  Enhancer of mRNA-decapping protein 4 (EDC4) LDTP07521 100.00  LDD0244  Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2) LDTP11998 100.00  LDD0244  ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 100.00  LDD0244  Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 100.00  LDD0244  Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 100.00  LDD0244  Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 100.00  LDD0244  Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 17.11  LDD0244  Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 6.15  LDD0244  Eukaryotic translation initiation factor 3 subunit D (EIF3D) LDTP00619 100.00  LDD0244  Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 100.00  LDD0244  Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 100.00  LDD0244  Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 100.00  LDD0244  Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 9.94  LDD0244  Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) LDTP05421 100.00  LDD0244  Eukaryotic translation initiation factor 6 (EIF6) LDTP04743 100.00  LDD0244  Exocyst complex component 1-like (EXOC1L) LDTP20089 D73; D78; K80; Q75  LDD0247  Ezrin (EZR) LDTP02779 12.20  LDD0244  F-actin-capping protein subunit beta (CAPZB) LDTP04127 100.00  LDD0244  F-BAR and double SH3 domains protein 2 (FCHSD2) LDTP01443 Y519  LDD0247  Far upstream element-binding protein 2 (KHSRP) LDTP09938 100.00  LDD0244  Fermitin family homolog 2 (FERMT2) LDTP10076 C127  LDD0247  Filamin A-interacting protein 1-like (FILIP1L) LDTP06857 E596; E599  LDD0247  Filamin-A-interacting protein 1 (FILIP1) LDTP08141 H188  LDD0247  Galectin-8 (LGALS8) LDTP00217 N83  LDD0247  Girdin (CCDC88A) LDTP06804 E1229  LDD0247  Golgi integral membrane protein 4 (GOLIM4) LDTP00281 Q413; Q414  LDD0247  Golgin subfamily A member 4 (GOLGA4) LDTP05872 D335; H337; K334; M338  LDD0247  Granule associated Rac and RHOG effector protein 1 (GARRE1) LDTP14439 Q704  LDD0247  GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 100.00  LDD0244  Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 100.00  LDD0244  Heat shock 70 kDa protein 1B (HSPA1B) LDTP02435 100.00  LDD0244  Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 100.00  LDD0244  Heat shock protein 105 kDa (HSPH1) LDTP09811 100.00  LDD0244  Heat shock protein beta-1 (HSPB1) LDTP02053 100.00  LDD0244  Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 100.00  LDD0244  Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 3.98  LDD0244  Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 6.06  LDD0244  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 100.00  LDD0244  Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 14.51  LDD0244  Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 100.00  LDD0244  Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 2.36  LDD0244  Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 14.44  LDD0244  Heterogeneous nuclear ribonucleoprotein L (HNRNPL) LDTP02750 12.51  LDD0244  Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 100.00  LDD0244  Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 100.00  LDD0244  Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 100.00  LDD0244  Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 6.91  LDD0244  Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 100.00  LDD0244  Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 3.86  LDD0244  Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 100.00  LDD0244  Histone-binding protein RBBP7 (RBBP7) LDTP06562 100.00  LDD0244  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 100.00  LDD0244  Interactor of HORMAD1 protein 1 (IHO1) LDTP08635 Q87; Q91  LDD0247  Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) LDTP00463 100.00  LDD0244  Inverted formin-2 (INF2) LDTP06681 100.00  LDD0244  Kelch-like ECH-associated protein 1 (KEAP1) LDTP06051 100.00  LDD0244  KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) LDTP05525 100.00  LDD0244  Kinesin light chain 2 (KLC2) LDTP11695 100.00  LDD0244  Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 100.00  LDD0244  Large ribosomal subunit protein eL30 (RPL30) LDTP05021 11.25  LDD0244  Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 3.40  LDD0244  Large ribosomal subunit protein eL38 (RPL38) LDTP05051 100.00  LDD0244  Large ribosomal subunit protein eL42 (RPL36A) LDTP05188 2.81  LDD0244  Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 100.00  LDD0244  Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 11.30  LDD0244  Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 2.30  LDD0244  Large ribosomal subunit protein uL11 (RPL12) LDTP03517 4.81  LDD0244  Large ribosomal subunit protein uL14 (RPL23) LDTP05008 3.73  LDD0244  Large ribosomal subunit protein uL16 (RPL10) LDTP03395 4.62  LDD0244  Large ribosomal subunit protein uL18 (RPL5) LDTP04106 5.42  LDD0244  Large ribosomal subunit protein uL22 (RPL17) LDTP02961 6.91  LDD0244  Large ribosomal subunit protein uL23 (RPL23A) LDTP05001 100.00  LDD0244  Large ribosomal subunit protein uL5 (RPL11) LDTP05026 10.01  LDD0244  Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 4.50  LDD0244  Leiomodin-3 (LMOD3) LDTP05608 Q206; Q208  LDD0247  Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 17.70  LDD0244  Leukocyte elastase inhibitor (SERPINB1) LDTP03557 100.00  LDD0244  LIM and SH3 domain protein 1 (LASP1) LDTP06220 100.00  LDD0244  LINE-1 retrotransposable element ORF2 protein LDTP00259 Q646  LDD0247  Matrin-3 (MATR3) LDTP04027 100.00  LDD0244  Meiosis-specific nuclear structural protein 1 (MNS1) LDTP09157 M309  LDD0247  Metallothionein-1X (MT1X) LDTP05159 100.00  LDD0244  MICAL-like protein 1 (MICALL1) LDTP08830 H730; H733  LDD0247  Microtubule-associated protein 4 (MAP4) LDTP03404 100.00  LDD0244  Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B) LDTP14125 R12; R15  LDD0247  Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 100.00  LDD0244  Motile sperm domain-containing protein 2 (MOSPD2) LDTP09255 D124  LDD0247  Muskelin (MKLN1) LDTP13525 Q309  LDD0247  Myb-binding protein 1A (MYBBP1A) LDTP11079 13.24  LDD0244  Myosin light polypeptide 6 (MYL6) LDTP04875 100.00  LDD0244  Myosin regulatory light chain 12A (MYL12A) LDTP02982 100.00  LDD0244  Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 100.00  LDD0244  Neurofilament heavy polypeptide (NEFH) LDTP02600 D106  LDD0247  Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 E696  LDD0247  Nucleolin (NCL) LDTP02990 100.00  LDD0244  Nucleophosmin (NPM1) LDTP02164 3.50  LDD0244  Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) LDTP13795 T897; T909  LDD0247  NudC domain-containing protein 1 (NUDCD1) LDTP10781 100.00  LDD0244  PDZ and LIM domain protein 5 (PDLIM5) LDTP10383 100.00  LDD0244  PDZ and LIM domain protein 7 (PDLIM7) LDTP12461 100.00  LDD0244  Periaxin (PRX) LDTP11393 M1058  LDD0247  Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B) LDTP08408 M205; M206  LDD0247  Pescadillo homolog (PES1) LDTP00306 7.96  LDD0244  PGAP2-interacting protein (CWH43) LDTP18404 K379; K383  LDD0247  Photoreceptor cilium actin regulator (PCARE) LDTP00097 K543; M540  LDD0247  Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 100.00  LDD0244  Plectin (PLEC) LDTP06330 8.83  LDD0244  Poly(rC)-binding protein 1 (PCBP1) LDTP06366 5.41  LDD0244  Polyadenylate-binding protein 1 (PABPC1) LDTP02595 100.00  LDD0244  Polyadenylate-binding protein 4 (PABPC4) LDTP05821 100.00  LDD0244  Polymerase delta-interacting protein 2 (POLDIP2) LDTP13906 100.00  LDD0244  Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 100.00  LDD0244  Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 10.73  LDD0244  Pre-mRNA-splicing factor SYF1 (XAB2) LDTP12269 M1; M4  LDD0247  Prelamin-A/C (LMNA) LDTP01932 23.71  LDD0244  Profilin-1 (PFN1) LDTP02218 4.45  LDD0244  Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 100.00  LDD0244  Prohibitin-2 (PHB2) LDTP10924 100.00  LDD0244  Proline-rich protein 5 (PRR5) LDTP05203 Y106  LDD0247  Protein CIP2A (CIP2A) LDTP09383 100.00  LDD0244  Protein DEK (DEK) LDTP03778 100.00  LDD0244  Protein diaphanous homolog 1 (DIAPH1) LDTP01011 100.00  LDD0244  Protein FAM220A (FAM220A) LDTP17542 Q223  LDD0247  Protein Niban 2 (NIBAN2) LDTP10847 100.00  LDD0244  Protein PALS1 (PALS1) LDTP08840 D80  LDD0247  Protein RCC2 (RCC2) LDTP13020 100.00  LDD0244  Protein SDA1 homolog (SDAD1) LDTP12694 100.00  LDD0244  Protein SPMIP7 (SPMIP7) LDTP18740 N166  LDD0247  Protein strawberry notch homolog 2 (SBNO2) LDTP13864 Y895  LDD0247  Protein transport protein Sec23B (SEC23B) LDTP06391 100.00  LDD0244  Protein unc-13 homolog C (UNC13C) LDTP09042 T46; T50  LDD0247  Protocadherin Fat 1 (FAT1) LDTP06134 E111; K113; R110  LDD0247  Putative cleavage and polyadenylation specificity factor subunit 4-like protein (CPSF4L) LDTP18855 C68  LDD0247  Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 100.00  LDD0244  Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 54.03  LDD0244  Ral guanine nucleotide dissociation stimulator-like 2 (RGL2) LDTP00572 K416; K417  LDD0247  RalBP1-associated Eps domain-containing protein 2 (REPS2) LDTP09205 Q650  LDD0247  Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 19.25  LDD0244  Replication protein A 70 kDa DNA-binding subunit (RPA1) LDTP03397 100.00  LDD0244  Reticulon-3 (RTN3) LDTP01522 100.00  LDD0244  Reticulon-4 (RTN4) LDTP12412 100.00  LDD0244  Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 100.00  LDD0244  Ribosome biogenesis protein BOP1 (BOP1) LDTP06046 100.00  LDD0244  Ribosome maturation protein SBDS (SBDS) LDTP13966 100.00  LDD0244  Ribosome-binding protein 1 (RRBP1) LDTP13044 100.00  LDD0244  RNA-binding protein FXR1 (FXR1) LDTP04395 100.00  LDD0244  Sacsin (SACS) LDTP12906 Q4576; Q4577  LDD0247  Sarcolemmal membrane-associated protein (SLMAP) LDTP06254 D71; T72; Q70  LDD0247  Sequestosome-1 (SQSTM1) LDTP05898 100.00  LDD0244  Serpin H1 (SERPINH1) LDTP04363 100.00  LDD0244  Sialate:O-sulfotransferase 2 (WSCD2) LDTP17086 D150  LDD0247  Sickle tail protein homolog (KIAA1217) LDTP07123 Q665; Q667  LDD0247  Signal-induced proliferation-associated 1-like protein 3 (SIPA1L3) LDTP00940 K1769  LDD0247  Sin3 histone deacetylase corepressor complex component SDS3 (SUDS3) LDTP12028 D281; Q283  LDD0247  Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 100.00  LDD0244  Sister chromatid cohesion protein PDS5 homolog B (PDS5B) LDTP12605 D1010  LDD0247  Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 3.27  LDD0244  Small ribosomal subunit protein eS12 (RPS12) LDTP03321 100.00  LDD0244  Small ribosomal subunit protein eS17 (RPS17) LDTP02302 100.00  LDD0244  Small ribosomal subunit protein eS19 (RPS19) LDTP03864 100.00  LDD0244  Small ribosomal subunit protein eS25 (RPS25) LDTP05013 8.86  LDD0244  Small ribosomal subunit protein eS27 (RPS27) LDTP03987 4.17  LDD0244  Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 2.18  LDD0244  Small ribosomal subunit protein uS10 (RPS20) LDTP04880 100.00  LDD0244  Small ribosomal subunit protein uS11 (RPS14) LDTP04970 5.96  LDD0244  Small ribosomal subunit protein uS12 (RPS23) LDTP04971 2.74  LDD0244  Small ribosomal subunit protein uS17 (RPS11) LDTP04975 2.20  LDD0244  Small ribosomal subunit protein uS2 (RPSA) LDTP02312 100.00  LDD0244  Small ribosomal subunit protein uS5 (RPS2) LDTP02809 3.68  LDD0244  Small ribosomal subunit protein uS7 (RPS5) LDTP04110 100.00  LDD0244  Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 7.82  LDD0244  Small ribosomal subunit protein uS9 (RPS16) LDTP04966 2.83  LDD0244  Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 100.00  LDD0244  Spectrin beta chain, non-erythrocytic 2 (SPTBN2) LDTP00510 D1705; E1707; E1712; W1709  LDD0247  Sperm-associated microtubule inner protein 5 (SPMIP5) LDTP18091 Y49  LDD0247  Splicing factor 3A subunit 1 (SF3A1) LDTP06393 Q180  LDD0247  Splicing factor 3B subunit 1 (SF3B1) LDTP01251 100.00  LDD0244  Src substrate cortactin (CTTN) LDTP06094 100.00  LDD0244  Stalled ribosome sensor GCN1 (GCN1) LDTP09821 100.00  LDD0244  Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 56.00  LDD0244  Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 100.00  LDD0244  Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (SVEP1) LDTP06859 M2075  LDD0247  T-complex protein 1 subunit alpha (TCP1) LDTP02934 5.02  LDD0244  T-complex protein 1 subunit beta (CCT2) LDTP05113 3.76  LDD0244  T-complex protein 1 subunit epsilon (CCT5) LDTP04201 100.00  LDD0244  T-complex protein 1 subunit eta (CCT7) LDTP10990 5.91  LDD0244  T-complex protein 1 subunit gamma (CCT3) LDTP04249 3.48  LDD0244  T-complex protein 1 subunit theta (CCT8) LDTP04390 6.69  LDD0244  T-complex protein 1 subunit zeta (CCT6A) LDTP03888 4.09  LDD0244  TBC1 domain family member 2B (TBC1D2B) LDTP13721 Q423; Q424  LDD0247  Tetratricopeptide repeat protein 31 (TTC31) LDTP19297 C197  LDD0247  Tetratricopeptide repeat protein 5 (TTC5) LDTP08738 Y24  LDD0247  Thrombospondin-1 (THBS1) LDTP02238 100.00  LDD0244  Thyroid receptor-interacting protein 11 (TRIP11) LDTP06431 D466; E734; E735  LDD0247  Tight junction protein ZO-2 (TJP2) LDTP13192 100.00  LDD0244  Transgelin-2 (TAGLN2) LDTP03846 100.00  LDD0244  Tubulin beta chain (TUBB) LDTP02205 3.50  LDD0244  Tubulin beta-4B chain (TUBB4B) LDTP05076 2.06  LDD0244  Tumor protein D54 (TPD52L2) LDTP00759 100.00  LDD0244  Type-1 angiotensin II receptor-associated protein (AGTRAP) LDTP07632 100.00  LDD0244  Ubiquitin-like protein ISG15 (ISG15) LDTP02092 5.15  LDD0244  Uncharacterized protein C11orf98 (C11orf98) LDTP20164 E29  LDD0247  Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 100.00  LDD0244  Vesicle-trafficking protein SEC22b (SEC22B) LDTP01206 100.00  LDD0244  Vimentin (VIM) LDTP02297 3.37  LDD0244  Vinculin (VCL) LDTP02946 100.00  LDD0244  WD repeat-containing protein 1 (WDR1) LDTP01118 13.31  LDD0244  WD repeat-containing protein 73 (WDR73) LDTP07536 E71  LDD0247  Zinc finger CCCH domain-containing protein 11A (ZC3H11A) LDTP01143 100.00  LDD0244  Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 4.53  LDD0244  Zinc finger protein 185 (ZNF185) LDTP00580 100.00  LDD0244  Zinc finger protein 862 (ZNF862) LDTP16803 K762; R763  LDD0247  Zinc finger RNA-binding protein (ZFR) LDTP15762 100.00  LDD0244  ------------------------------------------------------------------------------------ ⏷ Show the Full List of 270 Other

1	Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.