Details of the Target

General Information of Target

Target ID LDTP00451
Target Name Secretory carrier-associated membrane protein 3 (SCAMP3)
Gene Name SCAMP3
Gene ID 10067
Synonyms
C1orf3; PROPIN1; Secretory carrier-associated membrane protein 3; Secretory carrier membrane protein 3
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAQSRDGGNPFAEPSELDNPFQDPAVIQHRPSRQYATLDVYNPFETREPPPAYEPPAPAP
LPPPSAPSLQPSRKLSPTEPKNYGSYSTQASAAAATAELLKKQEELNRKAEELDRREREL
QHAALGGTATRQNNWPPLPSFCPVQPCFFQDISMEIPQEFQKTVSTMYYLWMCSTLALLL
NFLACLASFCVETNNGAGFGLSILWVLLFTPCSFVCWYRPMYKAFRSDSSFNFFVFFFIF
FVQDVLFVLQAIGIPGWGFSGWISALVVPKGNTAVSVLMLLVALLFTGIAVLGIVMLKRI
HSLYRRTGASFQKAQQEFAAGVFSNPAVRTAAANAAAGAAENAFRAP
Target Bioclass
Transporter and channel
Family
SCAMP family
Subcellular location
Membrane
Function Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Uniprot ID
O14828
Ensemble ID
ENST00000302631.8
HGNC ID
HGNC:10565

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
COLO792 SNV: p.A274V .
NCIH1155 SNV: p.A331T .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 20 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HDSF-alk
 Probe Info  		1.72  LDD0197  [1]
CHEMBL5175495
 Probe Info  		7.75  LDD0196  [2]
CY-1
 Probe Info  		100.00  LDD0243  [3]
CY4
 Probe Info  		100.00  LDD0244  [3]
N1
 Probe Info  		100.00  LDD0242  [3]
YN-1
 Probe Info  		100.00  LDD0444  [4]
YN-4
 Probe Info  		100.00  LDD0445  [4]
ONAyne
 Probe Info  		K102(0.71)  LDD0274  [5]
STPyne
 Probe Info  		K313(9.19); K81(8.33)  LDD0277  [5]
OPA-S-S-alkyne
 Probe Info  		K102(1.06)  LDD3494  [6]
Probe 1
 Probe Info  		Y35(8.62)  LDD3495  [7]
Johansson_61
 Probe Info  		_(20.00)  LDD1490  [8]
HPAP
 Probe Info  		4.02  LDD0062  [9]
Acrolein
 Probe Info  		N.A.  LDD0223  [10]
DBIA
 Probe Info  		C142(1.40); C147(1.40)  LDD1094  [11]
5E-2FA
 Probe Info  		N.A.  LDD2235  [12]
m-APA
 Probe Info  		H29(0.00); H122(0.00)  LDD2231  [12]
NHS
 Probe Info  		N.A.  LDD0010  [13]
1c-yne
 Probe Info  		N.A.  LDD0228  [14]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [10]
PAL-AfBPP Probe
Click To Hide/Show 19 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C027
 Probe Info  		8.51  LDD1733  [15]
C091
 Probe Info  		14.12  LDD1782  [15]
C092
 Probe Info  		25.11  LDD1783  [15]
C094
 Probe Info  		42.22  LDD1785  [15]
C220
 Probe Info  		12.04  LDD1894  [15]
C231
 Probe Info  		12.21  LDD1904  [15]
C310
 Probe Info  		8.00  LDD1977  [15]
FFF probe11
 Probe Info  		14.37  LDD0471  [16]
FFF probe12
 Probe Info  		12.90  LDD0473  [16]
FFF probe13
 Probe Info  		14.01  LDD0475  [16]
FFF probe14
 Probe Info  		12.33  LDD0477  [16]
FFF probe2
 Probe Info  		20.00  LDD0463  [16]
FFF probe3
 Probe Info  		10.44  LDD0464  [16]
JN0003
 Probe Info  		20.00  LDD0469  [16]
STS-2
 Probe Info  		1.00  LDD0139  [17]
VE-P
 Probe Info  		N.A.  LDD0396  [18]
DA-2
 Probe Info  		N.A.  LDD0072  [19]
KIRA6 AfBP
 Probe Info  		N.A.  LDD0378  [20]
OEA-DA
 Probe Info  		3.96  LDD0046  [21]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 PaTu 8988t C142(1.40); C147(1.40)  LDD1094  [11]
 LDCM0226  AC11 PaTu 8988t C142(1.10); C147(1.10)  LDD1105  [11]
 LDCM0230  AC113 PaTu 8988t C142(1.43); C147(1.43)  LDD1109  [11]
 LDCM0231  AC114 PaTu 8988t C142(1.24); C147(1.24)  LDD1110  [11]
 LDCM0232  AC115 PaTu 8988t C142(1.38); C147(1.38)  LDD1111  [11]
 LDCM0233  AC116 PaTu 8988t C142(0.98); C147(0.98)  LDD1112  [11]
 LDCM0234  AC117 PaTu 8988t C142(1.16); C147(1.16)  LDD1113  [11]
 LDCM0235  AC118 PaTu 8988t C142(1.16); C147(1.16)  LDD1114  [11]
 LDCM0236  AC119 PaTu 8988t C142(2.20); C147(2.20)  LDD1115  [11]
 LDCM0237  AC12 PaTu 8988t C142(1.54); C147(1.54)  LDD1116  [11]
 LDCM0238  AC120 PaTu 8988t C142(1.03); C147(1.03)  LDD1117  [11]
 LDCM0239  AC121 PaTu 8988t C142(1.06); C147(1.06)  LDD1118  [11]
 LDCM0240  AC122 PaTu 8988t C142(1.08); C147(1.08)  LDD1119  [11]
 LDCM0241  AC123 PaTu 8988t C142(0.93); C147(0.93)  LDD1120  [11]
 LDCM0242  AC124 PaTu 8988t C142(1.14); C147(1.14)  LDD1121  [11]
 LDCM0243  AC125 PaTu 8988t C142(0.90); C147(0.90)  LDD1122  [11]
 LDCM0244  AC126 PaTu 8988t C142(1.03); C147(1.03)  LDD1123  [11]
 LDCM0245  AC127 PaTu 8988t C142(1.16); C147(1.16)  LDD1124  [11]
 LDCM0246  AC128 PaTu 8988t C142(1.23); C147(1.23)  LDD1125  [11]
 LDCM0247  AC129 PaTu 8988t C142(1.03); C147(1.03)  LDD1126  [11]
 LDCM0249  AC130 PaTu 8988t C142(1.04); C147(1.04)  LDD1128  [11]
 LDCM0250  AC131 PaTu 8988t C142(1.09); C147(1.09)  LDD1129  [11]
 LDCM0251  AC132 PaTu 8988t C142(1.12); C147(1.12)  LDD1130  [11]
 LDCM0252  AC133 PaTu 8988t C142(1.08); C147(1.08)  LDD1131  [11]
 LDCM0253  AC134 PaTu 8988t C142(1.03); C147(1.03)  LDD1132  [11]
 LDCM0254  AC135 PaTu 8988t C142(1.18); C147(1.18)  LDD1133  [11]
 LDCM0255  AC136 PaTu 8988t C142(1.23); C147(1.23)  LDD1134  [11]
 LDCM0256  AC137 PaTu 8988t C142(1.15); C147(1.15)  LDD1135  [11]
 LDCM0257  AC138 PaTu 8988t C142(1.07); C147(1.07)  LDD1136  [11]
 LDCM0258  AC139 PaTu 8988t C142(1.11); C147(1.11)  LDD1137  [11]
 LDCM0259  AC14 PaTu 8988t C142(1.08); C147(1.08)  LDD1138  [11]
 LDCM0260  AC140 PaTu 8988t C142(0.94); C147(0.94)  LDD1139  [11]
 LDCM0261  AC141 PaTu 8988t C142(1.24); C147(1.24)  LDD1140  [11]
 LDCM0262  AC142 PaTu 8988t C142(1.05); C147(1.05)  LDD1141  [11]
 LDCM0270  AC15 PaTu 8988t C142(1.17); C147(1.17)  LDD1149  [11]
 LDCM0276  AC17 PaTu 8988t C142(1.42); C147(1.42)  LDD1155  [11]
 LDCM0277  AC18 PaTu 8988t C142(1.76); C147(1.76)  LDD1156  [11]
 LDCM0278  AC19 PaTu 8988t C142(1.45); C147(1.45)  LDD1157  [11]
 LDCM0280  AC20 PaTu 8988t C142(1.34); C147(1.34)  LDD1159  [11]
 LDCM0281  AC21 PaTu 8988t C142(1.52); C147(1.52)  LDD1160  [11]
 LDCM0282  AC22 PaTu 8988t C142(1.97); C147(1.97)  LDD1161  [11]
 LDCM0283  AC23 PaTu 8988t C142(1.54); C147(1.54)  LDD1162  [11]
 LDCM0284  AC24 PaTu 8988t C142(1.23); C147(1.23)  LDD1163  [11]
 LDCM0285  AC25 PaTu 8988t C142(0.73); C147(0.73)  LDD1164  [11]
 LDCM0286  AC26 PaTu 8988t C142(0.68); C147(0.68)  LDD1165  [11]
 LDCM0287  AC27 PaTu 8988t C142(0.97); C147(0.97)  LDD1166  [11]
 LDCM0288  AC28 PaTu 8988t C142(1.17); C147(1.17)  LDD1167  [11]
 LDCM0289  AC29 PaTu 8988t C142(0.87); C147(0.87)  LDD1168  [11]
 LDCM0291  AC30 PaTu 8988t C142(0.63); C147(0.63)  LDD1170  [11]
 LDCM0292  AC31 PaTu 8988t C142(0.69); C147(0.69)  LDD1171  [11]
 LDCM0293  AC32 PaTu 8988t C142(0.61); C147(0.61)  LDD1172  [11]
 LDCM0294  AC33 PaTu 8988t C142(0.84); C147(0.84)  LDD1173  [11]
 LDCM0295  AC34 PaTu 8988t C142(1.00); C147(1.00)  LDD1174  [11]
 LDCM0296  AC35 PaTu 8988t C142(0.90); C147(0.90)  LDD1175  [11]
 LDCM0297  AC36 PaTu 8988t C142(1.23); C147(1.23)  LDD1176  [11]
 LDCM0298  AC37 PaTu 8988t C142(1.17); C147(1.17)  LDD1177  [11]
 LDCM0299  AC38 PaTu 8988t C142(0.75); C147(0.75)  LDD1178  [11]
 LDCM0300  AC39 PaTu 8988t C142(0.97); C147(0.97)  LDD1179  [11]
 LDCM0302  AC40 PaTu 8988t C142(1.29); C147(1.29)  LDD1181  [11]
 LDCM0303  AC41 PaTu 8988t C142(0.71); C147(0.71)  LDD1182  [11]
 LDCM0304  AC42 PaTu 8988t C142(1.54); C147(1.54)  LDD1183  [11]
 LDCM0305  AC43 PaTu 8988t C142(0.94); C147(0.94)  LDD1184  [11]
 LDCM0306  AC44 PaTu 8988t C142(1.18); C147(1.18)  LDD1185  [11]
 LDCM0307  AC45 PaTu 8988t C142(1.20); C147(1.20)  LDD1186  [11]
 LDCM0308  AC46 PaTu 8988t C142(1.49); C147(1.49)  LDD1187  [11]
 LDCM0309  AC47 PaTu 8988t C142(1.22); C147(1.22)  LDD1188  [11]
 LDCM0310  AC48 PaTu 8988t C142(1.38); C147(1.38)  LDD1189  [11]
 LDCM0311  AC49 PaTu 8988t C142(1.19); C147(1.19)  LDD1190  [11]
 LDCM0313  AC50 PaTu 8988t C142(1.54); C147(1.54)  LDD1192  [11]
 LDCM0314  AC51 PaTu 8988t C142(2.26); C147(2.26)  LDD1193  [11]
 LDCM0315  AC52 PaTu 8988t C142(1.03); C147(1.03)  LDD1194  [11]
 LDCM0316  AC53 PaTu 8988t C142(1.68); C147(1.68)  LDD1195  [11]
 LDCM0317  AC54 PaTu 8988t C142(2.03); C147(2.03)  LDD1196  [11]
 LDCM0318  AC55 PaTu 8988t C142(1.05); C147(1.05)  LDD1197  [11]
 LDCM0319  AC56 PaTu 8988t C142(2.01); C147(2.01)  LDD1198  [11]
 LDCM0320  AC57 PaTu 8988t C142(0.93); C147(0.93)  LDD1199  [11]
 LDCM0321  AC58 PaTu 8988t C142(1.04); C147(1.04)  LDD1200  [11]
 LDCM0322  AC59 PaTu 8988t C142(0.93); C147(0.93)  LDD1201  [11]
 LDCM0323  AC6 PaTu 8988t C142(1.19); C147(1.19)  LDD1202  [11]
 LDCM0324  AC60 PaTu 8988t C142(0.99); C147(0.99)  LDD1203  [11]
 LDCM0325  AC61 PaTu 8988t C142(1.02); C147(1.02)  LDD1204  [11]
 LDCM0326  AC62 PaTu 8988t C142(0.91); C147(0.91)  LDD1205  [11]
 LDCM0327  AC63 PaTu 8988t C142(0.93); C147(0.93)  LDD1206  [11]
 LDCM0328  AC64 PaTu 8988t C142(1.05); C147(1.05)  LDD1207  [11]
 LDCM0329  AC65 PaTu 8988t C142(1.18); C147(1.18)  LDD1208  [11]
 LDCM0330  AC66 PaTu 8988t C142(1.42); C147(1.42)  LDD1209  [11]
 LDCM0331  AC67 PaTu 8988t C142(0.95); C147(0.95)  LDD1210  [11]
 LDCM0332  AC68 PaTu 8988t C142(0.96); C147(0.96)  LDD1211  [11]
 LDCM0333  AC69 PaTu 8988t C142(1.01); C147(1.01)  LDD1212  [11]
 LDCM0334  AC7 PaTu 8988t C142(0.95); C147(0.95)  LDD1213  [11]
 LDCM0335  AC70 PaTu 8988t C142(1.00); C147(1.00)  LDD1214  [11]
 LDCM0336  AC71 PaTu 8988t C142(1.04); C147(1.04)  LDD1215  [11]
 LDCM0337  AC72 PaTu 8988t C142(1.12); C147(1.12)  LDD1216  [11]
 LDCM0338  AC73 PaTu 8988t C142(1.11); C147(1.11)  LDD1217  [11]
 LDCM0339  AC74 PaTu 8988t C142(1.05); C147(1.05)  LDD1218  [11]
 LDCM0340  AC75 PaTu 8988t C142(1.08); C147(1.08)  LDD1219  [11]
 LDCM0341  AC76 PaTu 8988t C142(1.04); C147(1.04)  LDD1220  [11]
 LDCM0342  AC77 PaTu 8988t C142(1.16); C147(1.16)  LDD1221  [11]
 LDCM0343  AC78 PaTu 8988t C142(1.02); C147(1.02)  LDD1222  [11]
 LDCM0344  AC79 PaTu 8988t C142(1.06); C147(1.06)  LDD1223  [11]
 LDCM0345  AC8 PaTu 8988t C142(1.06); C147(1.06)  LDD1224  [11]
 LDCM0346  AC80 PaTu 8988t C142(1.17); C147(1.17)  LDD1225  [11]
 LDCM0347  AC81 PaTu 8988t C142(1.28); C147(1.28)  LDD1226  [11]
 LDCM0348  AC82 PaTu 8988t C142(1.11); C147(1.11)  LDD1227  [11]
 LDCM0248  AKOS034007472 PaTu 8988t C142(1.04); C147(1.04)  LDD1127  [11]
 LDCM0356  AKOS034007680 PaTu 8988t C142(1.61); C147(1.61)  LDD1235  [11]
 LDCM0275  AKOS034007705 PaTu 8988t C142(1.76); C147(1.76)  LDD1154  [11]
 LDCM0370  CL101 PaTu 8988t C142(1.23); C147(1.23)  LDD1249  [11]
 LDCM0371  CL102 PaTu 8988t C142(1.47); C147(1.47)  LDD1250  [11]
 LDCM0372  CL103 PaTu 8988t C142(1.36); C147(1.36)  LDD1251  [11]
 LDCM0373  CL104 PaTu 8988t C142(1.48); C147(1.48)  LDD1252  [11]
 LDCM0374  CL105 PaTu 8988t C142(1.10); C147(1.10)  LDD1253  [11]
 LDCM0375  CL106 PaTu 8988t C142(1.30); C147(1.30)  LDD1254  [11]
 LDCM0376  CL107 PaTu 8988t C142(1.25); C147(1.25)  LDD1255  [11]
 LDCM0377  CL108 PaTu 8988t C142(1.52); C147(1.52)  LDD1256  [11]
 LDCM0378  CL109 PaTu 8988t C142(1.77); C147(1.77)  LDD1257  [11]
 LDCM0380  CL110 PaTu 8988t C142(1.35); C147(1.35)  LDD1259  [11]
 LDCM0381  CL111 PaTu 8988t C142(2.27); C147(2.27)  LDD1260  [11]
 LDCM0382  CL112 PaTu 8988t C142(0.62); C147(0.62)  LDD1261  [11]
 LDCM0383  CL113 PaTu 8988t C142(0.62); C147(0.62)  LDD1262  [11]
 LDCM0384  CL114 PaTu 8988t C142(0.80); C147(0.80)  LDD1263  [11]
 LDCM0385  CL115 PaTu 8988t C142(0.77); C147(0.77)  LDD1264  [11]
 LDCM0386  CL116 PaTu 8988t C142(0.89); C147(0.89)  LDD1265  [11]
 LDCM0387  CL117 PaTu 8988t C142(0.85); C147(0.85)  LDD1266  [11]
 LDCM0388  CL118 PaTu 8988t C142(1.58); C147(1.58)  LDD1267  [11]
 LDCM0389  CL119 PaTu 8988t C142(0.90); C147(0.90)  LDD1268  [11]
 LDCM0391  CL120 PaTu 8988t C142(0.86); C147(0.86)  LDD1270  [11]
 LDCM0392  CL121 PaTu 8988t C142(1.56); C147(1.56)  LDD1271  [11]
 LDCM0393  CL122 PaTu 8988t C142(0.99); C147(0.99)  LDD1272  [11]
 LDCM0394  CL123 PaTu 8988t C142(1.18); C147(1.18)  LDD1273  [11]
 LDCM0395  CL124 PaTu 8988t C142(2.37); C147(2.37)  LDD1274  [11]
 LDCM0396  CL125 PaTu 8988t C142(0.92); C147(0.92)  LDD1275  [11]
 LDCM0397  CL126 PaTu 8988t C142(1.19); C147(1.19)  LDD1276  [11]
 LDCM0398  CL127 PaTu 8988t C142(0.83); C147(0.83)  LDD1277  [11]
 LDCM0399  CL128 PaTu 8988t C142(1.33); C147(1.33)  LDD1278  [11]
 LDCM0403  CL16 PaTu 8988t C142(1.13); C147(1.13)  LDD1282  [11]
 LDCM0404  CL17 PaTu 8988t C142(1.44); C147(1.44)  LDD1283  [11]
 LDCM0405  CL18 PaTu 8988t C142(1.86); C147(1.86)  LDD1284  [11]
 LDCM0406  CL19 PaTu 8988t C142(2.01); C147(2.01)  LDD1285  [11]
 LDCM0408  CL20 PaTu 8988t C142(2.62); C147(2.62)  LDD1287  [11]
 LDCM0409  CL21 PaTu 8988t C142(2.36); C147(2.36)  LDD1288  [11]
 LDCM0410  CL22 PaTu 8988t C142(2.05); C147(2.05)  LDD1289  [11]
 LDCM0411  CL23 PaTu 8988t C142(2.24); C147(2.24)  LDD1290  [11]
 LDCM0412  CL24 PaTu 8988t C142(1.64); C147(1.64)  LDD1291  [11]
 LDCM0413  CL25 PaTu 8988t C142(2.05); C147(2.05)  LDD1292  [11]
 LDCM0414  CL26 PaTu 8988t C142(1.66); C147(1.66)  LDD1293  [11]
 LDCM0415  CL27 PaTu 8988t C142(1.48); C147(1.48)  LDD1294  [11]
 LDCM0416  CL28 PaTu 8988t C142(1.79); C147(1.79)  LDD1295  [11]
 LDCM0417  CL29 PaTu 8988t C142(2.39); C147(2.39)  LDD1296  [11]
 LDCM0419  CL30 PaTu 8988t C142(1.94); C147(1.94)  LDD1298  [11]
 LDCM0420  CL31 PaTu 8988t C142(0.95); C147(0.95)  LDD1299  [11]
 LDCM0421  CL32 PaTu 8988t C142(1.38); C147(1.38)  LDD1300  [11]
 LDCM0422  CL33 PaTu 8988t C142(2.32); C147(2.32)  LDD1301  [11]
 LDCM0423  CL34 PaTu 8988t C142(1.40); C147(1.40)  LDD1302  [11]
 LDCM0424  CL35 PaTu 8988t C142(1.89); C147(1.89)  LDD1303  [11]
 LDCM0425  CL36 PaTu 8988t C142(1.48); C147(1.48)  LDD1304  [11]
 LDCM0426  CL37 PaTu 8988t C142(1.82); C147(1.82)  LDD1305  [11]
 LDCM0428  CL39 PaTu 8988t C142(1.26); C147(1.26)  LDD1307  [11]
 LDCM0430  CL40 PaTu 8988t C142(1.43); C147(1.43)  LDD1309  [11]
 LDCM0431  CL41 PaTu 8988t C142(2.02); C147(2.02)  LDD1310  [11]
 LDCM0432  CL42 PaTu 8988t C142(2.06); C147(2.06)  LDD1311  [11]
 LDCM0433  CL43 PaTu 8988t C142(2.34); C147(2.34)  LDD1312  [11]
 LDCM0434  CL44 PaTu 8988t C142(1.87); C147(1.87)  LDD1313  [11]
 LDCM0435  CL45 PaTu 8988t C142(1.44); C147(1.44)  LDD1314  [11]
 LDCM0436  CL46 PaTu 8988t C142(0.95); C147(0.95)  LDD1315  [11]
 LDCM0437  CL47 PaTu 8988t C142(0.89); C147(0.89)  LDD1316  [11]
 LDCM0438  CL48 PaTu 8988t C142(0.99); C147(0.99)  LDD1317  [11]
 LDCM0439  CL49 PaTu 8988t C142(0.95); C147(0.95)  LDD1318  [11]
 LDCM0441  CL50 PaTu 8988t C142(1.15); C147(1.15)  LDD1320  [11]
 LDCM0442  CL51 PaTu 8988t C142(1.12); C147(1.12)  LDD1321  [11]
 LDCM0443  CL52 PaTu 8988t C142(1.02); C147(1.02)  LDD1322  [11]
 LDCM0444  CL53 PaTu 8988t C142(1.19); C147(1.19)  LDD1323  [11]
 LDCM0445  CL54 PaTu 8988t C142(1.14); C147(1.14)  LDD1324  [11]
 LDCM0446  CL55 PaTu 8988t C142(1.02); C147(1.02)  LDD1325  [11]
 LDCM0447  CL56 PaTu 8988t C142(0.63); C147(0.63)  LDD1326  [11]
 LDCM0448  CL57 PaTu 8988t C142(1.70); C147(1.70)  LDD1327  [11]
 LDCM0449  CL58 PaTu 8988t C142(1.25); C147(1.25)  LDD1328  [11]
 LDCM0450  CL59 PaTu 8988t C142(1.52); C147(1.52)  LDD1329  [11]
 LDCM0452  CL60 PaTu 8988t C142(1.41); C147(1.41)  LDD1331  [11]
 LDCM0453  CL61 PaTu 8988t C142(0.95); C147(0.95)  LDD1332  [11]
 LDCM0454  CL62 PaTu 8988t C142(0.91); C147(0.91)  LDD1333  [11]
 LDCM0455  CL63 PaTu 8988t C142(0.92); C147(0.92)  LDD1334  [11]
 LDCM0456  CL64 PaTu 8988t C142(1.38); C147(1.38)  LDD1335  [11]
 LDCM0457  CL65 PaTu 8988t C142(1.01); C147(1.01)  LDD1336  [11]
 LDCM0458  CL66 PaTu 8988t C142(1.20); C147(1.20)  LDD1337  [11]
 LDCM0459  CL67 PaTu 8988t C142(1.28); C147(1.28)  LDD1338  [11]
 LDCM0460  CL68 PaTu 8988t C142(1.53); C147(1.53)  LDD1339  [11]
 LDCM0461  CL69 PaTu 8988t C142(1.82); C147(1.82)  LDD1340  [11]
 LDCM0463  CL70 PaTu 8988t C142(1.30); C147(1.30)  LDD1342  [11]
 LDCM0464  CL71 PaTu 8988t C142(1.00); C147(1.00)  LDD1343  [11]
 LDCM0465  CL72 PaTu 8988t C142(0.89); C147(0.89)  LDD1344  [11]
 LDCM0466  CL73 PaTu 8988t C142(1.54); C147(1.54)  LDD1345  [11]
 LDCM0467  CL74 PaTu 8988t C142(0.96); C147(0.96)  LDD1346  [11]
 LDCM0469  CL76 PaTu 8988t C142(1.08); C147(1.08)  LDD1348  [11]
 LDCM0470  CL77 PaTu 8988t C142(1.06); C147(1.06)  LDD1349  [11]
 LDCM0471  CL78 PaTu 8988t C142(1.14); C147(1.14)  LDD1350  [11]
 LDCM0472  CL79 PaTu 8988t C142(1.14); C147(1.14)  LDD1351  [11]
 LDCM0474  CL80 PaTu 8988t C142(1.33); C147(1.33)  LDD1353  [11]
 LDCM0475  CL81 PaTu 8988t C142(1.32); C147(1.32)  LDD1354  [11]
 LDCM0476  CL82 PaTu 8988t C142(1.11); C147(1.11)  LDD1355  [11]
 LDCM0477  CL83 PaTu 8988t C142(1.20); C147(1.20)  LDD1356  [11]
 LDCM0478  CL84 PaTu 8988t C142(1.84); C147(1.84)  LDD1357  [11]
 LDCM0479  CL85 PaTu 8988t C142(1.14); C147(1.14)  LDD1358  [11]
 LDCM0480  CL86 PaTu 8988t C142(1.14); C147(1.14)  LDD1359  [11]
 LDCM0481  CL87 PaTu 8988t C142(1.96); C147(1.96)  LDD1360  [11]
 LDCM0482  CL88 PaTu 8988t C142(1.49); C147(1.49)  LDD1361  [11]
 LDCM0483  CL89 PaTu 8988t C142(1.53); C147(1.53)  LDD1362  [11]
 LDCM0485  CL90 PaTu 8988t C142(1.62); C147(1.62)  LDD1364  [11]
 LDCM0468  Fragment33 PaTu 8988t C142(1.27); C147(1.27)  LDD1347  [11]
 LDCM0427  Fragment51 PaTu 8988t C142(1.61); C147(1.61)  LDD1306  [11]
 LDCM0617  Fragment63-S Jurkat _(20.00)  LDD1490  [8]
 LDCM0109  NEM HeLa N.A.  LDD0223  [10]
 LDCM0014  Panhematin HEK-293T 4.02  LDD0062  [9]

References

1 Fatty Acyl Sulfonyl Fluoride as an Activity-Based Probe for Profiling Fatty Acid-Associated Proteins in Living Cells. Chembiochem. 2022 Feb 16;23(4):e202100628. doi: 10.1002/cbic.202100628. Epub 2021 Dec 30.
2 Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.
3 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
4 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
5 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
6 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
7 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
8 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
9 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
10 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
11 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
12 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
13 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
14 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
15 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
16 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
17 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
18 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
19 Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes. J Am Chem Soc. 2012 Feb 15;134(6):3001-14. doi: 10.1021/ja208518u. Epub 2012 Feb 1.
20 Kinase Photoaffinity Labeling Reveals Low Selectivity Profile of the IRE1 Targeting Imidazopyrazine-Based KIRA6 Inhibitor. ACS Chem Biol. 2020 Dec 18;15(12):3106-3111. doi: 10.1021/acschembio.0c00802. Epub 2020 Dec 8.
Mass spectrometry data entry: PXD022628
21 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570