Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C091  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 172 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01803  Adenosine deaminase (ADA) 99.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 99.7
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 99.7
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 85.6
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 72.0
 LDTP00697  Cytochrome b5 type B (CYB5B) 64.9
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 54.2
 LDTP11127  ADP-dependent glucokinase (ADPGK) 48.5
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 48.5
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 43.4
 LDTP05588  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) 43.1
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 42.5
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 41.4
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 41.1
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 40.8
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 40.5
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 39.9
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 38.6
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 36.5
 LDTP03540  Heme oxygenase 2 (HMOX2) 34.5
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 34.1
 LDTP10329  Ceramide synthase 2 (CERS2) 33.6
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 32.2
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 30.9
 LDTP10038  Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) 30.7
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 30.5
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 30.3
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 30.1
 LDTP06142  Squalene monooxygenase (SQLE) 28.6
 LDTP11957  Protein O-mannose kinase (POMK) 25.6
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 25.5
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 25.3
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 25.1
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 24.9
 LDTP05905  Acid ceramidase (ASAH1) 24.6
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 23.6
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 22.5
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 22.3
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 21.6
 LDTP10020  Ras-related protein Rab-24 (RAB24) 21.6
 LDTP09388  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) 21.4
 LDTP05638  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) 21.1
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 20.8
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 20.5
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 20.5
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 20.1
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 20.0
 LDTP15962  Protein-L-histidine N-pros-methyltransferase (METTL9) 19.8
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 19.8
 LDTP07931  Heme A synthase COX15 (COX15) 19.6
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 19.4
 LDTP09251  Atlastin-2 (ATL2) 19.3
 LDTP14264  Choline/ethanolaminephosphotransferase 1 (CEPT1) 19.3
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 19.2
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 19.2
 LDTP11284  Phosphatidylserine synthase 2 (PTDSS2) 18.9
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 18.8
 LDTP03145  Catechol O-methyltransferase (COMT) 18.6
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 18.5
 LDTP04531  Hexokinase-2 (HK2) 18.1
 LDTP00758  Thioredoxin-like protein 1 (TXNL1) 18.1
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 18.1
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 17.8
 LDTP07292  Metalloreductase STEAP3 (STEAP3) 17.6
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 17.1
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 17.1
 LDTP03394  Ceramide synthase 1 (CERS1) 17.0
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 17.0
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 17.0
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 16.9
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 16.9
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 16.8
 LDTP04581  Holocytochrome c-type synthase (HCCS) 16.6
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 16.4
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 16.3
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 16.2
 LDTP02000  3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) 16.0
 LDTP03419  Proteasome subunit beta type-5 (PSMB5) 15.9
 LDTP10318  Ubiquitin thioesterase OTUB1 (OTUB1) 15.9
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 15.8
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 15.5
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 15.2
 LDTP14278  Sulfide:quinone oxidoreductase, mitochondrial (SQOR) 15.0
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 14.9
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 14.7
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 14.5
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 14.5
 LDTP06617  Ceramide glucosyltransferase (UGCG) 14.4
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 14.4
 LDTP01560  NADH dehydrogenase 1 subunit C2 (NDUFC2) 14.3
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 14.3
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 14.2
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 14.2
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 14.1
 LDTP08532  Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) 14.0
 LDTP09060  Ubiquitin-associated domain-containing protein 2 (UBAC2) 14.0
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 13.6
 LDTP01986  NADH-ubiquinone oxidoreductase chain 5 (MT-ND5) 13.6
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 13.6
 LDTP11728  Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (QRSL1) 13.5
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 13.5
 LDTP02868  Fumarylacetoacetase (FAH) 13.5
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 13.5
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 13.5
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 13.0
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 13.0
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 12.7
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 12.6
 LDTP02679  Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) 12.6
 LDTP00400  Torsin-1B (TOR1B) 12.6
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 12.6
 LDTP01329  Lathosterol oxidase (SC5D) 12.5
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 12.5
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 12.5
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 12.4
 LDTP07591  Neutral cholesterol ester hydrolase 1 (NCEH1) 12.4
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 12.3
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 12.3
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 12.3
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 12.3
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 12.2
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 12.1
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 12.1
 LDTP12180  Retinol dehydrogenase 14 (RDH14) 12.0
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 12.0
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 12.0
 LDTP04032  Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) 12.0
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 12.0
 LDTP09043  Lysine-specific histone demethylase 2 (KDM1B) 11.9
 LDTP08530  Mitofusin-1 (MFN1) 11.9
 LDTP11225  Deoxyhypusine hydroxylase (DOHH) 11.8
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 11.7
 LDTP05228  Calcium-transporting ATPase type 2C member 1 (ATP2C1) 11.6
 LDTP04248  Deoxyhypusine synthase (DHPS) 11.4
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 11.4
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 11.2
 LDTP11867  UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) 11.2
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 11.0
 LDTP00416  CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) 10.9
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) 10.9
 LDTP07813  Sulfhydryl oxidase 2 (QSOX2) 10.9
 LDTP15155  Thiol S-methyltransferase TMT1B (TMT1B) 10.9
 LDTP06657  2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) 10.9
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 10.9
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 10.9
 LDTP02539  Lysosomal acid phosphatase (ACP2) 10.9
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 10.9
 LDTP06427  Translin (TSN) 10.9
 LDTP10432  ATP synthase membrane subunit K, mitochondrial (ATP5MK) 10.7
 LDTP11177  Mitochondrial ribosome-associated GTPase 1 (MTG1) 10.7
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 10.7
 LDTP04689  Adenosine kinase (ADK) 10.6
 LDTP03024  Plasma membrane calcium-transporting ATPase 1 (ATP2B1) 10.6
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 10.6
 LDTP03249  Plasma membrane calcium-transporting ATPase 4 (ATP2B4) 10.6
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 10.5
 LDTP04420  DNA replication ATP-dependent helicase/nuclease DNA2 (DNA2) 10.4
 LDTP05622  Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT2) 10.3
 LDTP00577  Dihydroxyacetone phosphate acyltransferase (GNPAT) 10.3
 LDTP02505  Lysosomal protective protein (CTSA) 10.3
 LDTP06721  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) 10.3
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 10.3
 LDTP00645  Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) 10.3
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 10.3
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 10.1
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 10.1
 LDTP08799  Lysophosphatidylserine lipase ABHD12 (ABHD12) 10.1
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 10.1
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 10.1
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 10.0
 LDTP08232  Glycerol-3-phosphate acyltransferase 4 (GPAT4) 10.0
 LDTP09578  Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (PTPMT1) 10.0
Transporter and channel
Click to Show/Hide to Show 123 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 82.1
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 73.0
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 66.7
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 56.9
 LDTP08881  Transmembrane protein 199 (TMEM199) 55.3
 LDTP16813  Tetraspanin-3 (TSPAN3) 54.9
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 54.2
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 51.6
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 45.9
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 45.6
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 36.0
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 35.8
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 35.3
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 34.5
 LDTP11250  MICOS complex subunit MIC26 (APOO) 33.4
 LDTP05900  Metaxin-1 (MTX1) 32.9
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 32.0
 LDTP10065  Transmembrane protein 230 (TMEM230) 31.1
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 30.9
 LDTP07236  Protein GPR107 (GPR107) 30.3
 LDTP15948  Transmembrane protein 126A (TMEM126A) 29.9
 LDTP08279  Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) 29.4
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 28.1
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 27.1
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 26.0
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 25.8
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 25.6
 LDTP11615  Protein tweety homolog 3 (TTYH3) 25.3
 LDTP02215  Prosaposin (PSAP) 24.8
 LDTP09788  Sorting nexin-19 (SNX19) 23.6
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 23.3
 LDTP11844  Protein spinster homolog 1 (SPNS1) 22.2
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 21.7
 LDTP01804  ATP synthase subunit a (MT-ATP6) 21.6
 LDTP07531  Sideroflexin-4 (SFXN4) 21.3
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 21.1
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 20.5
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 20.4
 LDTP12383  Protein GPR108 (GPR108) 19.7
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 19.0
 LDTP15967  Tetraspanin-10 (TSPAN10) 18.6
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 18.5
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 18.4
 LDTP11406  Transmembrane protein 59 (TMEM59) 18.4
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 18.3
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 18.1
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 18.0
 LDTP06633  Reticulon-1 (RTN1) 17.5
 LDTP11213  Nucleoporin NDC1 (NDC1) 17.3
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 16.9
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 16.8
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 15.9
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 15.8
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 15.7
 LDTP03869  Protein Mpv17 (MPV17) 15.7
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 15.3
 LDTP00405  Etoposide-induced protein 2.4 homolog (EI24) 14.9
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 14.7
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 14.6
 LDTP07667  Transmembrane protein 205 (TMEM205) 14.6
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 14.5
 LDTP08016  Proton-coupled amino acid transporter 1 (SLC36A1) 14.5
 LDTP11826  Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) 14.5
 LDTP00451  Secretory carrier-associated membrane protein 3 (SCAMP3) 14.1
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 14.0
 LDTP01454  SUN domain-containing protein 1 (SUN1) 14.0
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 13.9
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 13.8
 LDTP03952  Reduced folate transporter (SLC19A1) 13.8
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 13.7
 LDTP11041  Calcium uptake protein 1, mitochondrial (MICU1) 13.6
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 13.6
 LDTP10731  Sodium-coupled neutral amino acid symporter 2 (SLC38A2) 13.5
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 13.5
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 13.0
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 12.9
 LDTP00590  Protein RER1 (RER1) 12.8
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 12.8
 LDTP07058  Transmembrane protein 201 (TMEM201) 12.6
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 12.6
 LDTP10073  Protein RFT1 homolog (RFT1) 12.6
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 12.6
 LDTP13833  Integral membrane protein 2B (ITM2B) 12.5
 LDTP09204  Nucleoporin NUP35 (NUP35) 12.5
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 12.4
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 12.1
 LDTP04787  Transmembrane protein 33 (TMEM33) 12.1
 LDTP09288  Vang-like protein 1 (VANGL1) 12.1
 LDTP06855  Anoctamin-6 (ANO6) 12.0
 LDTP10148  Store-operated calcium entry-associated regulatory factor (SARAF) 12.0
 LDTP12451  Integral membrane protein 2C (ITM2C) 12.0
 LDTP12979  Transmembrane protein 14C (TMEM14C) 11.8
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 11.7
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 11.7
 LDTP11634  Derlin-2 (DERL2) 11.6
 LDTP04663  Bax inhibitor 1 (TMBIM6) 11.6
 LDTP10754  Pannexin-1 (PANX1) 11.6
 LDTP09789  Transmembrane 9 superfamily member 4 (TM9SF4) 11.6
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 11.5
 LDTP15838  Translocation protein SEC62 (SEC62) 11.5
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 11.4
 LDTP02894  Gap junction alpha-1 protein (GJA1) 11.4
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 11.4
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 11.4
 LDTP08030  Autophagy-related protein 9A (ATG9A) 11.2
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 11.2
 LDTP00592  Surfeit locus protein 4 (SURF4) 11.2
 LDTP16190  Protein FAM8A1 (FAM8A1) 10.9
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 10.8
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 10.8
 LDTP09028  Mitoguardin 1 (MIGA1) 10.7
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 10.5
 LDTP01060  PRA1 family protein 2 (PRAF2) 10.5
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 10.4
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 10.3
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 10.3
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 10.2
 LDTP03405  Calnexin (CANX) 10.1
 LDTP13953  Endophilin-B1 (SH3GLB1) 10.1
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 10.1
 LDTP17797  Transmembrane protein 104 (TMEM104) 10.1
 LDTP10621  Sideroflexin-2 (SFXN2) 10.1
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 23.3
Immunoglobulin
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 14.2
 LDTP03772  Basigin (BSG) 13.5
Other
Click to Show/Hide to Show 110 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 99.7
 LDTP12412  Reticulon-4 (RTN4) 99.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 95.0
 LDTP14458  Tetraspanin-6 (TSPAN6) 91.8
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 82.1
 LDTP01522  Reticulon-3 (RTN3) 73.0
 LDTP10056  Protein FAM162A (FAM162A) 64.9
 LDTP11143  Centromere protein K (CENPK) 64.4
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 53.1
 LDTP18883  Protein CEBPZOS (CEBPZOS) 47.2
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 44.9
 LDTP16080  Protein FAM114A2 (FAM114A2) 44.0
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 42.2
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 42.2
 LDTP01167  Reticulon-2 (RTN2) 41.1
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 39.1
 LDTP13086  Syntaxin-18 (STX18) 38.1
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 36.8
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 36.3
 LDTP14939  Membralin (TMEM259) 36.0
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 35.8
 LDTP05868  Protein unc-119 homolog A (UNC119) 32.4
 LDTP16006  Optic atrophy 3 protein (OPA3) 30.9
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 29.9
 LDTP09773  Protein FAM3C (FAM3C) 29.9
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 29.0
 LDTP05160  Nucleobindin-2 (NUCB2) 25.1
 LDTP08224  Protein LYRIC (MTDH) 25.1
 LDTP05375  Nucleobindin-1 (NUCB1) 24.9
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 23.6
 LDTP00397  Golgi SNAP receptor complex member 2 (GOSR2) 23.1
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 22.2
 LDTP19963  TraB domain-containing protein (TRABD) 21.4
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 20.4
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 20.0
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 19.4
 LDTP13797  HIG1 domain family member 1A, mitochondrial (HIGD1A) 19.2
 LDTP08796  Protein SYS1 homolog (SYS1) 19.2
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 18.5
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 18.3
 LDTP08000  Dymeclin (DYM) 17.3
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 17.3
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 17.3
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 17.1
 LDTP01494  Protein YIF1A (YIF1A) 17.0
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 16.9
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 16.7
 LDTP09108  Mitoregulin (MTLN) 16.6
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 16.4
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 16.1
 LDTP18569  PRELI domain containing protein 3B (PRELID3B) 16.1
 LDTP11113  Receptor expression-enhancing protein 2 (REEP2) 16.0
 LDTP00986  Syntaxin-10 (STX10) 15.8
 LDTP18272  Transmembrane protein 209 (TMEM209) 15.7
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 15.3
 LDTP15398  Protein FAM177A1 (FAM177A1) 15.2
 LDTP06097  Reticulocalbin-2 (RCN2) 15.1
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 15.1
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 15.0
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 14.9
 LDTP18132  Protein FAM136A (FAM136A) 14.9
 LDTP04356  Emerin (EMD) 14.8
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 14.8
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 14.4
 LDTP13114  C-type mannose receptor 2 (MRC2) 14.3
 LDTP06373  Mitochondrial import receptor subunit TOM20 homolog (TOMM20) 13.9
 LDTP14716  ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) 13.8
 LDTP19472  Protein NCBP2AS2 (NCBP2AS2) 13.8
 LDTP07255  Proteasome adapter and scaffold protein ECM29 (ECPAS) 13.7
 LDTP11239  Protein misato homolog 1 (MSTO1) 13.5
 LDTP15623  Neuferricin (CYB5D2) 13.5
 LDTP05054  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) 13.4
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 13.4
 LDTP06193  Raftlin (RFTN1) 13.3
 LDTP17659  ELMO domain-containing protein 2 (ELMOD2) 13.0
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 12.7
 LDTP12025  UPF0488 protein C8orf33 (C8orf33) 12.7
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 12.6
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 12.6
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 12.5
 LDTP09644  m-AAA protease-interacting protein 1, mitochondrial (MAIP1) 12.4
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 12.3
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 12.2
 LDTP08073  Tetratricopeptide repeat protein 21B (TTC21B) 12.1
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 11.9
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 11.5
 LDTP15284  Pre-mRNA-processing factor 39 (PRPF39) 11.5
 LDTP16285  Transducin beta-like protein 2 (TBL2) 11.5
 LDTP12746  Gem-associated protein 8 (GEMIN8) 11.4
 LDTP13954  Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) 11.3
 LDTP02927  Ganglioside GM2 activator (GM2A) 11.3
 LDTP15253  HEAT repeat-containing protein 3 (HEATR3) 11.2
 LDTP10357  RUS family member 1 (RUSF1) 11.0
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 11.0
 LDTP15887  Lipase maturation factor 2 (LMF2) 10.9
 LDTP02297  Vimentin (VIM) 10.9
 LDTP13779  60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) 10.7
 LDTP06368  Elongin-C (ELOC) 10.7
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) 10.7
 LDTP13863  DnaJ homolog subfamily C member 16 (DNAJC16) 10.6
 LDTP17652  Uncharacterized protein KIAA2013 (KIAA2013) 10.6
 LDTP06210  Golgin subfamily B member 1 (GOLGB1) 10.5
 LDTP08606  Nurim (NRM) 10.3
 LDTP06808  Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) 10.3
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 10.2
 LDTP04979  U6 snRNA-associated Sm-like protein LSm3 (LSM3) 10.2
 LDTP10185  FAS-associated factor 2 (FAF2) 10.1
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 10.1
 LDTP09324  Ganglioside-induced differentiation-associated protein 1 (GDAP1) 10.0
 LDTP07934  Synaptic vesicle glycoprotein 2A (SV2A) 10.0

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587