Details of the Target

General Information of Target

Target ID LDTP17797
Target Name Transmembrane protein 104 (TMEM104)
Gene Name TMEM104
Gene ID 54868
Synonyms
Transmembrane protein 104
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGVIGIQLVVTMVMASVMQKIIPHYSLARWLLCNGSLRWYQHPTEEELRILAGKQQKGKT
KKDRKYNGHIESKPLTIPKDIDLHLETKSVTEVDTLALHYFPEYQWLVDFTVAATVVYLV
TEVYYNFMKPTQEMNISLVWCLLVLSFAIKVLFSLTTHYFKVEDGGERSVCVTFGFFFFV
KAMAVLIVTENYLEFGLETGFTNFSDSAMQFLEKQGLESQSPVSKLTFKFFLAIFCSFIG
AFLTFPGLRLAQMHLDALNLATEKITQTLLHINFLAPLFMVLLWVKPITKDYIMNPPLGK
ESIPLMTEATFDTLRLWLIILLCALRLAMMRSHLQAYLNLAQKCVDQMKKEAGRISTVEL
QKMVARVFYYLCVIALQYVAPLVMLLHTTLLLKTLGNHSWGIYPESISTLPVDNSLLSNS
VYSELPSAEGKMKVTVTQITVALSSLKNIFTPLLFRGLLSFLTWWIAACLFSTSLFGLFY
HQYLTVA
Target Bioclass
Transporter and channel
Family
TMEM104 family
Subcellular location
Membrane
Uniprot ID
Q8NE00
Ensemble ID
ENST00000335464.10
HGNC ID
HGNC:25984

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2780 SNV: p.G319D .
MFE319 SNV: p.A268V .
OVCAR8 SNV: p.G144V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C455(2.12)  LDD0171  [1]
IPM
 Probe Info  		C455(0.89)  LDD1701  [2]
DBIA
 Probe Info  		C455(0.87)  LDD0531  [3]
VSF
 Probe Info  		N.A.  LDD0007  [4]
PAL-AfBPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C022
 Probe Info  		13.36  LDD1728  [5]
C026
 Probe Info  		7.84  LDD1732  [5]
C070
 Probe Info  		11.55  LDD1766  [5]
C091
 Probe Info  		10.13  LDD1782  [5]
C166
 Probe Info  		6.68  LDD1846  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA DM93 C455(2.12)  LDD0171  [1]
 LDCM0214  AC1 HCT 116 C455(0.87)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C455(1.09)  LDD0532  [3]
 LDCM0226  AC11 HCT 116 C455(1.20)  LDD0543  [3]
 LDCM0230  AC113 HCT 116 C455(0.97)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C455(0.83)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C455(1.02)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C455(1.20)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C455(0.94)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C455(0.99)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C455(0.99)  LDD0553  [3]
 LDCM0237  AC12 HCT 116 C455(1.07)  LDD0554  [3]
 LDCM0238  AC120 HCT 116 C455(0.92)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C455(0.74)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C455(0.93)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C455(0.74)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C455(0.81)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C455(0.81)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C455(0.86)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C455(0.87)  LDD0562  [3]
 LDCM0259  AC14 HCT 116 C455(0.98)  LDD0576  [3]
 LDCM0270  AC15 HCT 116 C455(0.98)  LDD0587  [3]
 LDCM0276  AC17 HEK-293T C455(1.00)  LDD1515  [6]
 LDCM0277  AC18 HEK-293T C455(1.13)  LDD1516  [6]
 LDCM0278  AC19 HEK-293T C455(0.96)  LDD1517  [6]
 LDCM0279  AC2 HCT 116 C455(0.99)  LDD0596  [3]
 LDCM0280  AC20 HEK-293T C455(1.01)  LDD1519  [6]
 LDCM0281  AC21 HEK-293T C455(1.05)  LDD1520  [6]
 LDCM0282  AC22 HEK-293T C455(1.02)  LDD1521  [6]
 LDCM0283  AC23 HEK-293T C455(1.07)  LDD1522  [6]
 LDCM0284  AC24 HEK-293T C455(0.97)  LDD1523  [6]
 LDCM0285  AC25 HCT 116 C455(1.14)  LDD0602  [3]
 LDCM0286  AC26 HCT 116 C455(1.19)  LDD0603  [3]
 LDCM0287  AC27 HCT 116 C455(1.04)  LDD0604  [3]
 LDCM0288  AC28 HCT 116 C455(1.37)  LDD0605  [3]
 LDCM0289  AC29 HCT 116 C455(1.34)  LDD0606  [3]
 LDCM0290  AC3 HCT 116 C455(0.87)  LDD0607  [3]
 LDCM0291  AC30 HCT 116 C455(1.40)  LDD0608  [3]
 LDCM0292  AC31 HCT 116 C455(1.23)  LDD0609  [3]
 LDCM0293  AC32 HCT 116 C455(1.27)  LDD0610  [3]
 LDCM0294  AC33 HCT 116 C455(1.12)  LDD0611  [3]
 LDCM0295  AC34 HCT 116 C455(1.11)  LDD0612  [3]
 LDCM0296  AC35 HCT 116 C455(0.98)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C455(0.92)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C455(0.96)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C455(0.86)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C455(0.92)  LDD0617  [3]
 LDCM0301  AC4 HCT 116 C455(0.81)  LDD0618  [3]
 LDCM0302  AC40 HCT 116 C455(0.98)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C455(0.99)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C455(0.94)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C455(1.05)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C455(1.04)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C455(1.06)  LDD0624  [3]
 LDCM0308  AC46 HCT 116 C455(1.05)  LDD0625  [3]
 LDCM0309  AC47 HCT 116 C455(1.01)  LDD0626  [3]
 LDCM0310  AC48 HCT 116 C455(0.94)  LDD0627  [3]
 LDCM0311  AC49 HCT 116 C455(1.17)  LDD0628  [3]
 LDCM0312  AC5 HCT 116 C455(0.87)  LDD0629  [3]
 LDCM0313  AC50 HCT 116 C455(1.05)  LDD0630  [3]
 LDCM0314  AC51 HCT 116 C455(0.85)  LDD0631  [3]
 LDCM0315  AC52 HCT 116 C455(0.88)  LDD0632  [3]
 LDCM0316  AC53 HCT 116 C455(1.07)  LDD0633  [3]
 LDCM0317  AC54 HCT 116 C455(1.05)  LDD0634  [3]
 LDCM0318  AC55 HCT 116 C455(1.16)  LDD0635  [3]
 LDCM0319  AC56 HCT 116 C455(1.32)  LDD0636  [3]
 LDCM0320  AC57 HCT 116 C455(1.56)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C455(1.44)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C455(1.60)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C455(1.15)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C455(1.40)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C455(1.53)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C455(1.70)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C455(1.45)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C455(1.68)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C455(2.27)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C455(2.15)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C455(2.54)  LDD0648  [3]
 LDCM0332  AC68 HEK-293T C455(0.80)  LDD0930  [3]
 LDCM0333  AC69 HEK-293T C455(1.10)  LDD0931  [3]
 LDCM0334  AC7 HCT 116 C455(1.17)  LDD0651  [3]
 LDCM0335  AC70 HEK-293T C455(0.88)  LDD0933  [3]
 LDCM0336  AC71 HEK-293T C455(0.94)  LDD0934  [3]
 LDCM0337  AC72 HEK-293T C455(1.18)  LDD0935  [3]
 LDCM0338  AC73 HEK-293T C455(0.89)  LDD0936  [3]
 LDCM0339  AC74 HEK-293T C455(0.75)  LDD0937  [3]
 LDCM0340  AC75 HEK-293T C455(0.72)  LDD0938  [3]
 LDCM0341  AC76 HEK-293T C455(0.77)  LDD0939  [3]
 LDCM0342  AC77 HEK-293T C455(0.89)  LDD0940  [3]
 LDCM0343  AC78 HEK-293T C455(0.79)  LDD0941  [3]
 LDCM0344  AC79 HEK-293T C455(0.82)  LDD0942  [3]
 LDCM0345  AC8 HCT 116 C455(1.20)  LDD0662  [3]
 LDCM0346  AC80 HEK-293T C455(0.62)  LDD0944  [3]
 LDCM0347  AC81 HEK-293T C455(0.72)  LDD0945  [3]
 LDCM0348  AC82 HEK-293T C455(1.00)  LDD0946  [3]
 LDCM0349  AC83 HCT 116 C455(1.21)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C455(1.06)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C455(1.13)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C455(1.38)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C455(1.16)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C455(1.31)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C455(1.30)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C455(1.38)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C455(1.21)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C455(1.28)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C455(1.13)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C455(1.31)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C455(1.25)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C455(1.19)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C455(1.34)  LDD0681  [3]
 LDCM0248  AKOS034007472 HCT 116 C455(1.03)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C455(1.32)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C455(1.04)  LDD0592  [3]
 LDCM0367  CL1 HCT 116 C455(1.03)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C455(1.04)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C455(0.96)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C455(0.95)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C455(1.10)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C455(0.94)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C455(1.01)  LDD0690  [3]
 LDCM0374  CL105 HEK-293T C455(0.92)  LDD1578  [6]
 LDCM0375  CL106 HEK-293T C455(0.99)  LDD1579  [6]
 LDCM0376  CL107 HEK-293T C455(1.03)  LDD1580  [6]
 LDCM0377  CL108 HEK-293T C455(0.98)  LDD1581  [6]
 LDCM0378  CL109 HEK-293T C455(1.02)  LDD1582  [6]
 LDCM0379  CL11 HCT 116 C455(1.01)  LDD0696  [3]
 LDCM0380  CL110 HEK-293T C455(1.08)  LDD1584  [6]
 LDCM0381  CL111 HEK-293T C455(1.11)  LDD1585  [6]
 LDCM0382  CL112 HCT 116 C455(1.15)  LDD0699  [3]
 LDCM0383  CL113 HCT 116 C455(1.36)  LDD0700  [3]
 LDCM0384  CL114 HCT 116 C455(1.39)  LDD0701  [3]
 LDCM0385  CL115 HCT 116 C455(1.14)  LDD0702  [3]
 LDCM0386  CL116 HCT 116 C455(0.98)  LDD0703  [3]
 LDCM0387  CL117 HCT 116 C455(0.92)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C455(1.05)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C455(1.06)  LDD0706  [3]
 LDCM0390  CL12 HCT 116 C455(0.96)  LDD0707  [3]
 LDCM0391  CL120 HCT 116 C455(0.96)  LDD0708  [3]
 LDCM0392  CL121 HCT 116 C455(1.04)  LDD0709  [3]
 LDCM0393  CL122 HCT 116 C455(0.96)  LDD0710  [3]
 LDCM0394  CL123 HCT 116 C455(1.12)  LDD0711  [3]
 LDCM0395  CL124 HCT 116 C455(1.18)  LDD0712  [3]
 LDCM0396  CL125 HCT 116 C455(1.15)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C455(1.17)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C455(1.31)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C455(1.49)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C455(0.97)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C455(1.01)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C455(1.04)  LDD0719  [3]
 LDCM0403  CL16 HCT 116 C455(1.27)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C455(1.12)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C455(1.06)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C455(1.06)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C455(1.06)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C455(1.16)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C455(1.28)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C455(0.95)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C455(1.13)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C455(1.08)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C455(1.19)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C455(0.96)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C455(1.02)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C455(1.23)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C455(1.05)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C455(0.92)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C455(1.35)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C455(1.10)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C455(1.02)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C455(1.12)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C455(1.16)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C455(1.19)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C455(1.06)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C455(1.09)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C455(1.05)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C455(1.22)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C455(1.24)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C455(1.18)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C455(0.98)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C455(1.08)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C455(1.11)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C455(1.24)  LDD0752  [3]
 LDCM0436  CL46 HCT 116 C455(0.99)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C455(0.93)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C455(0.89)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C455(1.02)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C455(1.09)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C455(0.95)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C455(1.04)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C455(0.92)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C455(0.99)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C455(0.96)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C455(0.77)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C455(0.89)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C455(1.02)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C455(0.88)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C455(0.97)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C455(1.33)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C455(0.92)  LDD0769  [3]
 LDCM0453  CL61 HCT 116 C455(1.11)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C455(0.92)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C455(1.06)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C455(1.09)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C455(0.89)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C455(1.21)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C455(0.94)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C455(1.04)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C455(1.05)  LDD0778  [3]
 LDCM0462  CL7 HCT 116 C455(1.35)  LDD0779  [3]
 LDCM0463  CL70 HCT 116 C455(1.05)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C455(0.99)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C455(0.96)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C455(1.10)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C455(1.01)  LDD0784  [3]
 LDCM0469  CL76 HEK-293T C455(1.06)  LDD1672  [6]
 LDCM0470  CL77 HEK-293T C455(1.09)  LDD1673  [6]
 LDCM0471  CL78 HEK-293T C455(1.00)  LDD1674  [6]
 LDCM0472  CL79 HEK-293T C455(0.93)  LDD1675  [6]
 LDCM0473  CL8 HCT 116 C455(1.06)  LDD0790  [3]
 LDCM0474  CL80 HEK-293T C455(1.12)  LDD1677  [6]
 LDCM0475  CL81 HEK-293T C455(1.21)  LDD1678  [6]
 LDCM0476  CL82 HEK-293T C455(1.20)  LDD1679  [6]
 LDCM0477  CL83 HEK-293T C455(1.39)  LDD1680  [6]
 LDCM0478  CL84 HEK-293T C455(1.24)  LDD1681  [6]
 LDCM0479  CL85 HEK-293T C455(1.21)  LDD1682  [6]
 LDCM0480  CL86 HEK-293T C455(1.04)  LDD1683  [6]
 LDCM0481  CL87 HEK-293T C455(1.22)  LDD1684  [6]
 LDCM0482  CL88 HEK-293T C455(1.09)  LDD1685  [6]
 LDCM0483  CL89 HEK-293T C455(1.13)  LDD1686  [6]
 LDCM0484  CL9 HCT 116 C455(1.12)  LDD0801  [3]
 LDCM0485  CL90 HEK-293T C455(1.07)  LDD1688  [6]
 LDCM0486  CL91 HCT 116 C455(0.78)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C455(0.88)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C455(0.98)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C455(1.01)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C455(1.13)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C455(0.90)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C455(0.98)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C455(1.08)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C455(0.93)  LDD0811  [3]
 LDCM0495  E2913 HEK-293T C455(1.03)  LDD1698  [6]
 LDCM0468  Fragment33 HCT 116 C455(1.00)  LDD0785  [3]
 LDCM0427  Fragment51 HCT 116 C455(1.47)  LDD0744  [3]
 LDCM0022  KB02 HEK-293T C455(1.02)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C455(0.99)  LDD1497  [6]
 LDCM0024  KB05 HEK-293T C455(0.93)  LDD1502  [6]

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402